Orangeburg South Carolina Accommodations

Find accommodations in Orangeburg with the hotel list provided below. Search for cheap and discounted hotel and motel rates in or close to Orangeburg, SC for your upcoming personal or group trip. We show the best Orangeburg South Carolina hotel rooms. Review the Orangeburg hotel list below to find the perfect lodging. We also have a map of the Orangeburg hotels. Planning a group? Lock in Orangeburg Group Hotel Deals

The Orangeburg center point is approximately 4 miles from Edisto Memorial Gardens and 19 miles from Denmark Amtrak.

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Orangeburg Hotels/Motels & Accommodations

Econo Lodge Inn & Suites : 1415 John C Calhoun Dr.
+1-800-230-4134Check Rates
1415 John C Calhoun Dr., Orangeburg, SC 29115
  • Economy hotel
  • Check in: 2.00pm
Image of Super 8Super 8 - Orangeburg
+1-800-997-5148Check Rates
610 John C Calhoun Dr., Orangeburg, SC 29115
  • 3.5/5, Average Recent Reviews
  • Low-priced Highway property
  • Hotel has 44 rooms
Exterior of Baymont Inn & SuitesBaymont Inn & Suites - Orangeburg
+1-800-997-5149Check Rates
2350 Chestnut St., Orangeburg, SC 29115
  • Economical Rural property
  • Check-in time: 3 pm
Image of Hampton Inn OrangeburgHampton Inn Orangeburg in Orangeburg
+1-800-230-4134Check Rates
3583 St. Matthews Rd., Orangeburg, SC 29118
  • 4.0/5, Very Good Reviews
  • Economical Highway property
  • 2 floors in hotel
Image of Southern LodgeSouthern Lodge
+1-800-997-5148Check Rates
3616 St. Matthews Rd., Orangeburg, SC 29118 Website
  • 2 star Highway hotel
  • Hotel has a green policy Learn more
Howard Johnson : 3608 St. Matthews Rd.
+1-800-997-5149Check Rates
3608 St. Matthews Rd., Orangeburg, SC 29118
Photo of Country Inn & SuitesCountry Inn & Suites
+1-800-230-4134Check Rates
731 Citadel Rd., Orangeburg, SC 29118
Photo of Fairfield Inn OrangeburgFairfield Inn Orangeburg : 663 Citadel
+1-800-997-5148Check Rates
663 Citadel, Orangeburg, SC 29118
Quality Inn & Suites
+1-800-997-5149Check Rates
3671 St. Matthews, Orangeburg, SC 29118
  • 2.0/5, Poor Review Score
  • Inexpensive Rural hotel
  • 91 rooms in hotel
Holiday Inn Express & Suites of Orangeburg - Orangeburg
+1-800-230-4134Check Rates
118 Sleep Inn Rd., Orangeburg, SC 29118
  • 4.0/5, Very Good Read Reviews
  • 3-star Rural hotel
  • 78 rooms in property
Sleep Inn Orangeburg - Orangeburg
+1-800-997-5148Check Rates
3689 Saint Matthews Rd., Orangeburg, SC 29118
Comfort Inn & Suites in Orangeburg
+1-800-997-5149Check Rates
746 Citadel Rd., Orangeburg, SC 29118 Website
  • 4.0/5, Very Good Read Reviews
  • Two-star Rural hotel
  • Hotel has 14 suites
Econo Lodge - Santee
+1-800-230-4134Check Rates
9112 Old Number 6 Hww., Santee, SC 29142
  • Economy Highway hotel
  • Free breakfast available
~20.35 Miles from Orangeburg
Travelodge in Santee
+1-800-997-5148Check Rates
9091 Old Highway 6, Santee, SC 29142
  • 2.5/5, Poor Recent Reviews
  • Inexpensive Golf Course hotel
  • 40 rooms in hotel
~21.22 Miles from Orangeburg
Best Western Plus Santee Inn - Santee
+1-800-997-5149Check Rates
9059 Old Number Six Highway, Santee, SC 29142
  • 3-star property
~21.69 Miles from Orangeburg
Rodeway Inn Santee
+1-800-230-4134Check Rates
9117 Old Number 6 Highway, Santee, SC 29142
  • 3.0/5, Average Hotel Reviews
  • Economical Highway hotel
  • Free breakfast available
~21.69 Miles from Orangeburg
Hampton Inn Santee I 95 in Santee
+1-800-997-5148Check Rates
9060 Old #6 Highway, Santee, SC 29142
  • 4.5/5, Very Good Guest Reviews
  • Midscale Highway property
  • 81 sleeping rooms in hotel
~21.93 Miles from Orangeburg
Days Inn
+1-800-997-5149Check Rates
9074 Old Highway Six, Santee, SC 29142
  • Economical property
~22.14 Miles from Orangeburg
Quality Inn & Suites
+1-800-230-4134Check Rates
8929 Old Number Six Highway, Santee, SC 29142
  • 3.0/5, Average Reviews
  • 2-star Highway hotel
  • 153 rooms in property
~22.18 Miles from Orangeburg
Holiday Inn Santee : 139 Bradford Blvd.
+1-800-997-5148Check Rates
139 Bradford Blvd., Santee, SC 29142
  • 3.0/5, Average Read Reviews
  • 3 star Highway hotel
  • Check in time: 4:00pm
~22.36 Miles from Orangeburg

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