26+ Best Hotels in Florence

Hotels in Florence SC & Motels in Florence South Carolina

Only hotels in Florence are listed below. Search for the cheapest discounted hotel and motel rates in or near Florence, SC for your personal leisure or group travel. We show the best Florence South Carolina hotel rooms. Review the Florence hotel list below to find the perfect lodging. We also have a map of the Florence hotels. Group booking? Search Florence Group Hotel Discounts or Book a Florence Meeting

The Florence center point is around the area of Florence Museum and 1 mile from Francis Marion Performing Arts Center.

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Florence Hotels, Motels & Accommodations

Image of Comfort SuitesComfort Suites in Florence
+1-800-230-4134Check Rates
2120 West Lucas St., Florence, SC 29501 Website
  • 4.5/5, Very Good Guest Reviews
  • 3-star Highway hotel
  • Check-in: 3:00 PM
Photo of Suburban Extended Stay HotelSuburban Extended Stay Hotel in Florence
+1-800-997-5148Check Rates
1914 West Lucas St., Florence, SC 29501
  • 3.0/5, Average Hotel Reviews
  • 2-star Highway hotel
  • Check in: 3:00 pm
Hotel Florence An Ascend Hotel Collection Member - Florence
+1-800-997-5149Check Rates
136 West Evans St., Florence, SC 29501
  • 5.0/5, Excellent Guest Reviews
  • Three Star Downtown hotel
  • Gym is available on property
Photo of Quality InnQuality Inn
+1-800-230-4134Check Rates
213 Us Highway 15 / 401 Bypass East, Bennettsville, SC 29512
  • 5.0/5, Excellent Hotel Reviews
  • Low-priced Highway property
  • Check-in time: 3:00 pm
~30.97 Miles from Florence
Photo of Residence Inn Florence ScResidence Inn Florence Sc
+1-800-997-5148Check Rates
2660 Hospitality Blvd., Florence, SC 29501
  • 4.5/5, Very Good Recent Reviews
  • Midscale Suburban hotel
  • 4 floors in property
Photo of Springhill Suites MarriottSpringhill Suites Marriott
+1-800-997-5149Check Rates
2670 Hospitality Blvd., Florence, SC 29501
  • 4.5/5, Very Good Hotel Reviews
  • Affordable Convention Center property
  • Free breakfast
Exterior of Hilton Garden InnHilton Garden Inn - Florence
+1-800-230-4134Check Rates
2671 Hospitality Blvd., Florence, SC 29501
  • 4.5/5, Very Good Review Score
  • 3-star Highway property
  • Hotel has 8 floors
Exterior of Hampton Ste Florence Civic CenterHampton Ste Florence Civic Center in Florence
+1-800-997-5148Check Rates
3000 Radio Dr., Florence, SC 29501
  • 4.5/5, Very Good Reviews
  • 2 star Convention Center property
  • Free complimentary breakfast
Hampton Inn & Suites in Florence
+1-800-997-5149Check Rates
1735 Stokes Rd., Florence, SC 29501
  • 4.5/5, Very Good Read Reviews
  • Low Cost Convention Center property
  • 36 suites in hotel
Holiday Inn Express & Suites Florence Civic Center - Florence
+1-800-230-4134Check Rates
3440 West Radio Dr., Florence, SC 29501
  • 4.5/5, Very Good Guest Reviews
  • Midscale Convention Center property
  • 3 floors in property
Best Western Executive Inn
+1-800-997-5148Check Rates
1534 Highway 38 West, Latta, SC 29565
  • 4.5/5, Very Good Read Reviews
  • Affordable Highway hotel
  • Check in time: 3:00 PM
~18.13 Miles from Florence
Quality Inn : 903 South 5th St.
+1-800-997-5149Check Rates
903 South 5th St., Hartsville, SC 29550
  • 4.5/5, Very Good Latest Reviews
  • Two-star Downtown property
  • Free complimentary breakfast
~20.42 Miles from Florence
Florence Courtyard by Marriott
+1-800-230-4134Check Rates
2680 Hospitality Blvd., Florence, SC 29501
  • 4.0/5, Very Good Recent Reviews
  • Affordable Convention Center property
  • 3 suites in property
Baymont Inn & Suites Florence in Florence
+1-800-997-5148Check Rates
1826 West Lucas St., Florence, SC 29501
  • 4.0/5, Very Good Read Reviews
  • Low-priced Highway property
  • Check-in: 3:00pm
Country Inn & Suites
+1-800-997-5149Check Rates
1739 Mandeville Rd., Florence, SC 29501
  • 4.0/5, Very Good Reviews
  • Midscale Highway hotel
  • Fitness + Health Center
Fairfield Inn Hartsville in Hartsville
+1-800-230-4134Check Rates
200 South 4th St., Hartsville, SC 29550
  • 4.0/5, Very Good Reviews
  • Low Cost Rural property
  • 3 floors in property
~21.14 Miles from Florence
Red Roof Inn
+1-800-997-5148Check Rates
2690 David Mcleod Blvd., Florence, SC 29501
  • 3.5/5, Average Latest Reviews
  • Low priced Highway property
  • Hotel has 2 floors
Best Western Florence
+1-800-997-5149Check Rates
1808 West Lucas St., Florence, SC 29501
  • 3.5/5, Average Hotel Reviews
  • Three Star Downtown hotel
  • 2 floors in property
Super 8 : I 95 Exit 164 Behind Citgo
+1-800-230-4134Check Rates
I 95 Exit 164 Behind Citgo, Florence, SC 29501
  • 3.5/5, Average Reviews
  • Economy Highway hotel
  • 2 floors in property
Comfort Inn
+1-800-997-5148Check Rates
1916 West Lucas St., Florence, SC 29501
  • 3.5/5, Average Read Reviews
  • Three Star Highway property
  • Hotel has 2 floors

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