Sikeston Missouri Accommodations

Find the perfect hotel in Sikeston using our hotel guide provided below. Search for cheap and discounted hotel and motel rates in or near Sikeston, MO for your business or personal leisure travel. We list the best Sikeston Missouri hotel rooms. Review the Sikeston hotel list below to find the perfect lodging. We also have a map of the Sikeston hotels. Coordinating a group? Get Sikeston Group Hotel Discounts


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Sikeston Hotels/Motels & Accommodations

Exterior of Pear Tree Inn SikestonPear Tree Inn Sikeston
+1-800-230-4134Check Rates
2602 East Malone, Sikeston, MO 63801
  • Mid-scale Suburban hotel
  • 80 rooms in hotel
Exterior of Super 8Super 8 - Sikeston
+1-800-997-5148Check Rates
2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Recent Reviews
  • Low-priced Convention Center hotel
  • 62 rooms in hotel
Image of Drury Inn & Suites SikestonDrury Inn & Suites Sikeston in Sikeston
+1-800-997-5149Check Rates
2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Review Score
  • Three Star Highway property
  • 14 suites in hotel
Exterior of Comfort Inn & SuitesComfort Inn & Suites
+1-800-230-4134Check Rates
109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Recent Reviews
  • Midscale Highway hotel
  • 17 suites in property
Exterior of Best Western Plus SikestonBest Western Plus Sikeston - Sikeston
+1-800-997-5148Check Rates
120 South Interstate Dr., Sikeston, MO 63801
  • Economical Highway hotel
  • Check-in time: 11:00AM
Exterior of Quality InnQuality Inn
+1-800-997-5149Check Rates
102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Hotel Reviews
  • Economical Highway hotel
  • 9 suites in property
~12.80 Miles from Sikeston
Photo of Super 8Super 8
+1-800-230-4134Check Rates
310 South Story, Charleston, MO 63834
  • 3.0/5, Average Review Score
  • Cheap Highway hotel
  • 7 suites in hotel
~14.40 Miles from Sikeston
Image of Eagle InnEagle Inn - Charleston
+1-800-997-5148Check Rates
2811 East Marshall St., Charleston, MO 63834
  • 3.5/5, Average Read Reviews
  • Economy hotel
  • Access to gym on-site
~15.51 Miles from Sikeston
Econo Lodge Dexter : 913 Outer Rd.
+1-800-997-5149Check Rates
913 Outer Rd., Dexter, MO 63841~22.25 Miles from Sikeston
Hickory House Inn
+1-800-230-4134Check Rates
1802 North Outer Rd., Dexter, MO 63841~23.35 Miles from Sikeston
Candlewood Suites Cape Girardeau
+1-800-997-5148Check Rates
485 South Mount Auburn Rd., Cape Girardeau, MO 65703
  • 4.0/5, Very Good Recent Reviews
  • 2 star Highway hotel
  • 4 floors in property
~27.56 Miles from Sikeston
Victorian Inn & Suites - Cape Girardeau
+1-800-997-5149Check Rates
3256 William St., Cape Girardeau, MO 63703
  • 3-star Golf Course property
  • Check-in: 3:00 pm
~28.38 Miles from Sikeston
Auburn Place Hotel & Suites : 3265 Williams St.
+1-800-230-4134Check Rates
3265 Williams St., Cape Girardeau, MO 63702
  • 4.0/5, Very Good Hotel Reviews
  • Three Star Highway property
  • Hotel has 2 floors
~28.39 Miles from Sikeston
Drury Suites Cape Girardeau in Cape Girardeau
+1-800-997-5148Check Rates
3303 Campster Dr., Cape Girardeau, MO 63701
  • 4.5/5, Very Good Latest Reviews
  • Mid-scale Highway hotel
  • 79 suites in hotel
~28.41 Miles from Sikeston
Holiday Inn Express Hotel & Suites in Cape Girardeau
+1-800-997-5149Check Rates
3253 William St., Cape Girardeau, MO 63701
  • 4.5/5, Very Good Recent Reviews
  • Three Star property
  • 7 suites in property
~28.42 Miles from Sikeston
Pear Tree Inn Cape Girardeau
+1-800-230-4134Check Rates
3248 William St., Cape Girardeau, MO 63701
  • Cheap Highway property
  • 78 rooms in hotel
~28.43 Miles from Sikeston
Drury Lodge Cape Girardeau
+1-800-997-5148Check Rates
104 South Vantage Dr., Cape Girardeau, MO 63701
  • Three Star Highway property
  • Hotel has 139 rooms
~28.63 Miles from Sikeston
Image of Comfort Suites Jackson / Cape GirardeauComfort Suites Jackson / Cape Girardeau : 2904 Old Orchard Rd.
+1-800-997-5149Check Rates
2904 Old Orchard Rd., Jackson, MO 63755 Website
  • 4.0/5, Very Good Read Reviews
  • 3-star Highway hotel
  • Comp. Breakfast
~32.09 Miles from Sikeston
Exterior of Drury Inn & Suites Jackson MissouriDrury Inn & Suites Jackson Missouri
+1-800-230-4134Check Rates
225 Drury Lane, Jackson, MO 63755
  • 4.5/5, Very Good Review Score
  • 3 star Suburban hotel
  • Check in: 3:00 PM
~37.27 Miles from Sikeston
Hampton Inn Union City : 2201 West Reelfoot Ave.
+1-800-997-5148Check Rates
2201 West Reelfoot Ave., Union City, TN 38261
  • 4.0/5, Very Good Reviews
  • Midscale Rural hotel
  • Fitness + Health Center
~43.50 Miles from Sikeston

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