Sikeston Missouri Accommodations

Find the perfect hotel in Sikeston using our hotel guide provided below. Search for cheap and discounted hotel and motel rates in or near Sikeston, MO for your business or personal leisure travel. We list the best Sikeston Missouri hotel rooms. Review the Sikeston hotel list below to find the perfect lodging. We also have a map of the Sikeston hotels. Coordinating a group? Get Sikeston Group Hotel Discounts


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Sikeston Hotels/Motels & Accommodations

Photo of Pear Tree Inn Sikeston Pear Tree Inn Sikeston - Sikeston
+1-800-230-4134Check Rates
2602 East Malone, Sikeston, MO 63801
  • 3 star Suburban property
  • 2 suites in property
Exterior of Drury Inn & Suites Sikeston Drury Inn & Suites Sikeston : 2608 East Malone Ave.
+1-800-997-5148Check Rates
2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Reviews
  • Three Star Highway property
  • Check-in time: 3:00 PM
Image of Super 8 Super 8 : 2609 East Malone Ave.
+1-800-997-5149Check Rates
2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Read Reviews
  • Two star Convention Center hotel
  • 2 floors in hotel
Image of Comfort Inn & Suites Comfort Inn & Suites
+1-800-230-4134Check Rates
109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Read Reviews
  • Midscale Highway property
  • Hotel has 17 suites
Photo of Best Western Plus Sikeston Best Western Plus Sikeston : 120 South Interstate Dr.
+1-800-997-5148Check Rates
120 South Interstate Dr., Sikeston, MO 63801
  • Two-star Highway property
  • Complimentary breakfast is offered
Exterior of Quality Inn Quality Inn : 102 Drake St.
+1-800-997-5149Check Rates
102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Reviews
  • 2 star Highway property
  • Free breakfast
~12.80 Miles from Sikeston
Exterior of Super 8 Super 8 - Charleston
+1-800-230-4134Check Rates
310 South Story, Charleston, MO 63834
  • 3.0/5, Average Latest Reviews
  • Cheap Highway hotel
  • Complimentary breakfast is offered
~14.40 Miles from Sikeston
Image of Eagle Inn Eagle Inn
+1-800-997-5148Check Rates
2811 East Marshall St., Charleston, MO 63834 ~15.51 Miles from Sikeston
Econo Lodge Dexter
+1-800-997-5149Check Rates
913 Outer Rd., Dexter, MO 63841
  • 3.0/5, Average Read Reviews
  • Economy property
  • 2 floors in hotel
~22.25 Miles from Sikeston
Hickory House Inn - Dexter
+1-800-230-4134Check Rates
1802 North Outer Rd., Dexter, MO 63841 ~23.35 Miles from Sikeston
Candlewood Suites Cape Girardeau - Cape Girardeau
+1-800-997-5148Check Rates
485 South Mount Auburn Rd., Cape Girardeau, MO 65703
  • 4.0/5, Very Good Reviews
  • Low priced Highway property
  • Hotel has an eco-friendly policy Learn more
~27.56 Miles from Sikeston
Victorian Inn & Suites - Cape Girardeau
+1-800-997-5149Check Rates
3256 William St., Cape Girardeau, MO 63703
  • Midscale Golf Course property
  • 2 meeting rooms in hotel
~28.38 Miles from Sikeston
Auburn Place Hotel & Suites in Cape Girardeau
+1-800-230-4134Check Rates
3265 Williams St., Cape Girardeau, MO 63702
  • 4.0/5, Very Good Read Reviews
  • 3 star Highway property
  • Check-in time: 0300 pm
~28.39 Miles from Sikeston
Drury Suites Cape Girardeau
+1-800-997-5148Check Rates
3303 Campster Dr., Cape Girardeau, MO 63701
  • 4.5/5, Very Good Read Reviews
  • 3 star Highway property
  • Complimentary breakfast is offered
~28.41 Miles from Sikeston
Holiday Inn Express Hotel & Suites
+1-800-997-5149Check Rates
3253 William St., Cape Girardeau, MO 63701
  • 4.5/5, Very Good Review Score
  • 3-star property
  • Check-in time: 11:00
~28.42 Miles from Sikeston
Pear Tree Inn Cape Girardeau
+1-800-230-4134Check Rates
3248 William St., Cape Girardeau, MO 63701
  • Low-priced Highway hotel
  • Free breakfast
~28.43 Miles from Sikeston
Drury Lodge Cape Girardeau - Cape Girardeau
+1-800-997-5148Check Rates
104 South Vantage Dr., Cape Girardeau, MO 63701
  • 3-star Highway property
  • 139 sleeping rooms in hotel
~28.63 Miles from Sikeston
Exterior of Comfort Suites Jackson / Cape Girardeau Comfort Suites Jackson / Cape Girardeau : 2904 Old Orchard Rd.
+1-800-997-5149Check Rates
2904 Old Orchard Rd., Jackson, MO 63755 Website
  • 4.5/5, Very Good Reviews
  • Mid-scale Highway property
  • Check-in: 3.00 pm
~32.09 Miles from Sikeston
Photo of Drury Inn & Suites Jackson Missouri Drury Inn & Suites Jackson Missouri
+1-800-230-4134Check Rates
225 Drury Lane, Jackson, MO 63755
  • 4.5/5, Very Good Reviews
  • Mid-scale Suburban hotel
  • Free comp. breakfast
~37.27 Miles from Sikeston
Hampton Inn : 5575 Skyhawk Pkwy.
+1-800-997-5148Check Rates
5575 Skyhawk Pkwy., Martin, TN 38261
  • 3 star Rural hotel
  • Free complimentary breakfast
~40.71 Miles from Sikeston

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