Sikeston Missouri Accommodations

Find the perfect hotel in Sikeston using our hotel guide provided below. Search for cheap and discounted hotel and motel rates in or near Sikeston, MO for your business or personal leisure travel. We list the best Sikeston Missouri hotel rooms. Review the Sikeston hotel list below to find the perfect lodging. We also have a map of the Sikeston hotels. Coordinating a group? Get Sikeston Group Hotel Discounts


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Sikeston Hotels, Motels & Accommodations

Photo of Pear Tree Inn Sikeston Pear Tree Inn Sikeston - Sikeston
+1-800-230-4134Check Rates
2602 East Malone, Sikeston, MO 63801
  • Midscale Suburban hotel
  • Comp. Breakfast
Image of Super 8 Super 8 : 2609 East Malone Ave.
+1-800-997-5148Check Rates
2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Read Reviews
  • Low priced Convention Center property
  • Hotel has 2 floors
Image of Drury Inn & Suites Sikeston Drury Inn & Suites Sikeston - Sikeston
+1-800-997-5149Check Rates
2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Hotel Reviews
  • 3-star Highway property
  • Check-in: 3:00 PM
Photo of Comfort Inn & Suites Comfort Inn & Suites in Sikeston
+1-800-230-4134Check Rates
109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Recent Reviews
  • Affordable Highway hotel
  • Hotel has 3 floors
Photo of Best Western Plus Sikeston Best Western Plus Sikeston - Sikeston
+1-800-997-5148Check Rates
120 South Interstate Dr., Sikeston, MO 63801
  • Economy Highway hotel
  • 55 rooms in property
Photo of Quality Inn Quality Inn
+1-800-997-5149Check Rates
102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Reviews
  • Economical Highway property
  • Gym / Fitness Center Available
~12.80 Miles from Sikeston
Image of Super 8 Super 8
+1-800-230-4134Check Rates
310 South Story, Charleston, MO 63834
  • 3.0/5, Average Latest Reviews
  • Low priced Highway hotel
  • 7 suites in hotel
~14.40 Miles from Sikeston
Photo of Eagle Inn Eagle Inn
+1-800-997-5148Check Rates
2811 East Marshall St., Charleston, MO 63834
  • 3.5/5, Average Latest Reviews
  • Low priced hotel
  • Fitness + Health Center
~15.51 Miles from Sikeston
Econo Lodge Dexter - Dexter
+1-800-997-5149Check Rates
913 Outer Rd., Dexter, MO 63841 ~22.25 Miles from Sikeston
Hickory House Inn in Dexter
+1-800-230-4134Check Rates
1802 North Outer Rd., Dexter, MO 63841 ~23.35 Miles from Sikeston
Candlewood Suites Cape Girardeau
+1-800-997-5148Check Rates
485 South Mount Auburn Rd., Cape Girardeau, MO 65703
  • 4.0/5, Very Good Recent Reviews
  • Cheap Highway hotel
  • 85 suites in hotel
~27.56 Miles from Sikeston
Victorian Inn & Suites : 3256 William St.
+1-800-997-5149Check Rates
3256 William St., Cape Girardeau, MO 63703
  • Affordable Golf Course property
  • Check in time: 3:00 pm
~28.38 Miles from Sikeston
Auburn Place Hotel & Suites
+1-800-230-4134Check Rates
3265 Williams St., Cape Girardeau, MO 63702
  • 4.0/5, Very Good Review Score
  • Affordable Highway hotel
  • Free breakfast available
~28.39 Miles from Sikeston
Drury Suites Cape Girardeau : 3303 Campster Dr.
+1-800-997-5148Check Rates
3303 Campster Dr., Cape Girardeau, MO 63701
  • 4.5/5, Very Good Latest Reviews
  • Mid-scale Highway property
  • 79 suites in hotel
~28.41 Miles from Sikeston
Holiday Inn Express Hotel & Suites - Cape Girardeau
+1-800-997-5149Check Rates
3253 William St., Cape Girardeau, MO 63701
  • 4.5/5, Very Good Hotel Reviews
  • 3-star property
  • 7 suites in property
~28.42 Miles from Sikeston
Pear Tree Inn Cape Girardeau
+1-800-230-4134Check Rates
3248 William St., Cape Girardeau, MO 63701
  • Two-star Highway hotel
  • 78 rooms in property
~28.43 Miles from Sikeston
Drury Lodge Cape Girardeau
+1-800-997-5148Check Rates
104 South Vantage Dr., Cape Girardeau, MO 63701
  • Three Star Highway hotel
  • 139 rooms in hotel
~28.63 Miles from Sikeston
Image of Comfort Suites Jackson / Cape Girardeau Comfort Suites Jackson / Cape Girardeau : 2904 Old Orchard Rd.
+1-800-997-5149Check Rates
2904 Old Orchard Rd., Jackson, MO 63755 Website
  • 4.5/5, Very Good Guest Reviews
  • Mid-scale Highway property
  • Check-in time: 3.00 pm
~32.09 Miles from Sikeston
Exterior of Drury Inn & Suites Jackson Missouri Drury Inn & Suites Jackson Missouri : 225 Drury Lane
+1-800-230-4134Check Rates
225 Drury Lane, Jackson, MO 63755
  • 4.5/5, Very Good Reviews
  • Three Star Suburban property
  • Check in time: 3:00 PM
~37.27 Miles from Sikeston
Hampton Inn
+1-800-997-5148Check Rates
5575 Skyhawk Pkwy., Martin, TN 38261
  • Mid-scale Rural hotel
  • 6 suites in property
~40.71 Miles from Sikeston

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