Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.


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Cairo Hotels/Motels & Accommodations

Exterior of Eagle InnEagle Inn - Charleston
+1-800-230-4134Check Rates
2811 East Marshall St., Charleston, MO 63834~9.29 Miles from Cairo
Image of Super 8Super 8 in Charleston
+1-800-997-5148Check Rates
310 South Story, Charleston, MO 63834
  • 3.0/5, Average Review Score
  • Low priced Highway hotel
  • Check-in: 3:00pm
~10.14 Miles from Cairo
Photo of Quality InnQuality Inn : 102 Drake St.
+1-800-997-5149Check Rates
102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Hotel Reviews
  • Two star Highway property
  • Hotel has 9 suites
~11.82 Miles from Cairo
Photo of Best Western Plus SikestonBest Western Plus Sikeston
+1-800-230-4134Check Rates
120 South Interstate Dr., Sikeston, MO 63801
  • Two-star Highway property
  • Gym is available on property
~20.97 Miles from Cairo
Image of Comfort Inn & SuitesComfort Inn & Suites in Sikeston
+1-800-997-5148Check Rates
109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Latest Reviews
  • Mid-scale Highway property
  • Free complimentary breakfast
~21.36 Miles from Cairo
Image of Drury Inn & Suites SikestonDrury Inn & Suites Sikeston - Sikeston
+1-800-997-5149Check Rates
2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Latest Reviews
  • 3 star Highway property
  • Gym / Fitness Center Available
~21.42 Miles from Cairo
Exterior of Super 8Super 8
+1-800-230-4134Check Rates
2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Read Reviews
  • Low Cost Convention Center hotel
  • 2 floors in property
~21.42 Miles from Cairo
Exterior of Pear Tree Inn SikestonPear Tree Inn Sikeston - Sikeston
+1-800-997-5148Check Rates
2602 East Malone, Sikeston, MO 63801
  • Mid-scale Suburban property
  • 4 floors in property
~21.42 Miles from Cairo
Residence Inn
+1-800-997-5149Check Rates
3900 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Hotel Reviews
  • Three Star Suburban hotel
  • Free complimentary breakfast
~25.70 Miles from Cairo
Pear Tree Inn Paducah
+1-800-230-4134Check Rates
5006 Hinkleville Rd., Paducah, KY 42001
  • 4.0/5, Very Good Hotel Reviews
  • Two-star Suburban property
  • Check in time: 3:00 PM
~25.80 Miles from Cairo
Baymont Inn & Suites Metropolis Il
+1-800-997-5148Check Rates
203 East Front St., Metropolis, IL 62960
  • 3.0/5, Average Review Score
  • Low-priced Riverfront property
  • Gym is available on property
~26.33 Miles from Cairo
Comfort Suites of Paducah in Paducah
+1-800-997-5149Check Rates
2880 James Sanders Blvd., Paducah, KY 42001~27.72 Miles from Cairo
Drury Suites Paducah
+1-800-230-4134Check Rates
2930 James Sanders Blvd., Paducah, KY 42001
  • 4.5/5, Very Good Reviews
  • Midscale Suburban hotel
  • Hotel has 142 rooms
~27.73 Miles from Cairo
Country Inn & Suites
+1-800-997-5148Check Rates
145 Mcbride Lane, Paducah, KY 42001
  • 4.0/5, Very Good Review Score
  • Mid-scale Highway hotel
  • 3 floors in hotel
~27.83 Miles from Cairo
La Quinta Inn & Suites in Paducah
+1-800-997-5149Check Rates
3960 Coleman Crossing Circle, Paducah, KY 42001
  • 3-star Highway property
  • Check-in time: 3;00PM
~27.93 Miles from Cairo
Candlewood Suites in Paducah
+1-800-230-4134Check Rates
3940 Coleman Crossing Circle, Paducah, KY 42001
  • 4.0/5, Very Good Recent Reviews
  • Cheap Rural property
  • 85 rooms in property
~27.94 Miles from Cairo
Exterior of Comfort Inn PaducahComfort Inn Paducah
+1-800-997-5148Check Rates
5135 Old Cairo Rd., Paducah, KY 42001 Website
  • 4.5/5, Very Good Reviews
  • 2-star hotel
  • Fitness + Health Center
~28.01 Miles from Cairo
Econo Lodge Paducah
+1-800-997-5149Check Rates
5106 Old Cairo Rd., Paducah, KY 42001~28.01 Miles from Cairo
Fairfield Inn & Suites
+1-800-230-4134Check Rates
3950 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Latest Reviews
  • Affordable Rural property
  • 32 suites in hotel
~28.03 Miles from Cairo
Hampton Inn & Suites : 3901 Coleman Crossing Circle
+1-800-997-5148Check Rates
3901 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Review Score
  • Midscale Highway hotel
  • 32 suites in property
~28.08 Miles from Cairo

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