Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.


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Cairo Hotels & Accommodations

Image of Eagle InnEagle Inn
+1-800-230-4134Check Rates
2811 East Marshall St., Charleston, MO 63834
  • 3.5/5, Average Review Score
  • Economical property
  • Check-in: 3:00PM
~9.29 Miles from Cairo
Image of Super 8Super 8
+1-800-997-5148Check Rates
310 South Story, Charleston, MO 63834
  • 3.5/5, Average Reviews
  • Inexpensive Highway property
  • Free comp. breakfast
~10.14 Miles from Cairo
Exterior of Quality InnQuality Inn
+1-800-997-5149Check Rates
102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Hotel Reviews
  • 2-star Highway property
  • Free comp. breakfast
~11.82 Miles from Cairo
Photo of Best Western Plus SikestonBest Western Plus Sikeston
+1-800-230-4134Check Rates
120 South Interstate Dr., Sikeston, MO 63801
  • Low priced Highway hotel
  • Hotel has a green policy Read more
~20.97 Miles from Cairo
Exterior of Comfort Inn & SuitesComfort Inn & Suites
+1-800-997-5148Check Rates
109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Review Score
  • 3-star Highway property
  • 17 suites in property
~21.36 Miles from Cairo
Exterior of Super 8Super 8 in Sikeston
+1-800-997-5149Check Rates
2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Read Reviews
  • Low Cost Convention Center property
  • 62 rooms in property
~21.42 Miles from Cairo
Photo of Drury Inn & Suites SikestonDrury Inn & Suites Sikeston in Sikeston
+1-800-230-4134Check Rates
2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Recent Reviews
  • Three Star Highway property
  • 5 floors in hotel
~21.42 Miles from Cairo
Photo of Pear Tree Inn SikestonPear Tree Inn Sikeston in Sikeston
+1-800-997-5148Check Rates
2602 East Malone, Sikeston, MO 63801
  • 3 star Suburban property
  • Gym is available on property
~21.42 Miles from Cairo
Residence Inn - Paducah
+1-800-997-5149Check Rates
3900 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Review Score
  • 3-star Suburban hotel
  • 74 suites in hotel
~25.70 Miles from Cairo
Pear Tree Inn Paducah
+1-800-230-4134Check Rates
5006 Hinkleville Rd., Paducah, KY 42001
  • 4.0/5, Very Good Read Reviews
  • 2 star Suburban property
  • Check-in time: 3:00 PM
~25.80 Miles from Cairo
Baymont Inn & Suites Metropolis Il in Metropolis
+1-800-997-5148Check Rates
203 East Front St., Metropolis, IL 62960
  • 3.0/5, Average Read Reviews
  • 2 star Riverfront property
  • Comp. Breakfast
~26.33 Miles from Cairo
Comfort Suites of Paducah
+1-800-997-5149Check Rates
2880 James Sanders Blvd., Paducah, KY 42001
  • 4.0/5, Very Good Reviews
  • 3 star property
  • Free complimentary breakfast
~27.72 Miles from Cairo
Drury Suites Paducah in Paducah
+1-800-230-4134Check Rates
2930 James Sanders Blvd., Paducah, KY 42001
  • 4.5/5, Very Good Read Reviews
  • Mid-scale Suburban property
  • Hotel has 142 rooms
~27.73 Miles from Cairo
Country Inn & Suites - Paducah
+1-800-997-5148Check Rates
145 Mcbride Lane, Paducah, KY 42001
  • 4.5/5, Very Good Recent Reviews
  • 3 star Highway hotel
  • 3 floors in property
~27.83 Miles from Cairo
La Quinta Inn & Suites
+1-800-997-5149Check Rates
3960 Coleman Crossing Circle, Paducah, KY 42001
  • Affordable Highway property
  • Fitness + Health Center
~27.93 Miles from Cairo
Candlewood Suites - Paducah
+1-800-230-4134Check Rates
3940 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Review Score
  • Low-priced Rural hotel
  • 4 floors in hotel
~27.94 Miles from Cairo
Photo of Comfort Inn PaducahComfort Inn Paducah
+1-800-997-5148Check Rates
5135 Old Cairo Rd., Paducah, KY 42001 Website
  • 4.5/5, Very Good Reviews
  • Economy property
  • Free comp. breakfast
~28.01 Miles from Cairo
Econo Lodge Paducah
+1-800-997-5149Check Rates
5106 Old Cairo Rd., Paducah, KY 42001~28.01 Miles from Cairo
Fairfield Inn & Suites
+1-800-230-4134Check Rates
3950 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Guest Reviews
  • Mid-scale Rural property
  • 32 suites in property
~28.03 Miles from Cairo
Hampton Inn & Suites - Paducah
+1-800-997-5148Check Rates
3901 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Hotel Reviews
  • 3-star Highway property
  • 108 rooms in property
~28.08 Miles from Cairo

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