Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.


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Cairo Hotels/Accommodations

Photo of Eagle InnEagle Inn in Charleston
+1-800-230-4134Check Rates
2811 East Marshall St., Charleston, MO 63834
  • 3.5/5, Average Recent Reviews
  • Inexpensive property
  • Check-in time: 3:00PM
~9.29 Miles from Cairo
Photo of Super 8Super 8
+1-800-997-5148Check Rates
310 South Story, Charleston, MO 63834
  • 3.0/5, Average Review Score
  • Cheap Highway property
  • Hotel has 7 suites
~10.14 Miles from Cairo
Image of Quality InnQuality Inn in Charleston
+1-800-997-5149Check Rates
102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Read Reviews
  • Two-star Highway property
  • Hotel has 2 floors
~11.82 Miles from Cairo
Image of Best Western Plus SikestonBest Western Plus Sikeston - Sikeston
+1-800-230-4134Check Rates
120 South Interstate Dr., Sikeston, MO 63801
  • Economical Highway hotel
  • Hotel has 55 rooms
~20.97 Miles from Cairo
Exterior of Comfort Inn & SuitesComfort Inn & Suites in Sikeston
+1-800-997-5148Check Rates
109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Review Score
  • Affordable Highway property
  • Check in time: 02:00 PM
~21.36 Miles from Cairo
Exterior of Drury Inn & Suites SikestonDrury Inn & Suites Sikeston
+1-800-997-5149Check Rates
2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Reviews
  • Three Star Highway hotel
  • Gym / Fitness Center Available
~21.42 Miles from Cairo
Image of Super 8Super 8 in Sikeston
+1-800-230-4134Check Rates
2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Read Reviews
  • Cheap Convention Center property
  • Check-in: 01:00
~21.42 Miles from Cairo
Image of Pear Tree Inn SikestonPear Tree Inn Sikeston - Sikeston
+1-800-997-5148Check Rates
2602 East Malone, Sikeston, MO 63801
  • Mid-scale Suburban property
  • Gym / Fitness Center Available
~21.42 Miles from Cairo
Residence Inn
+1-800-997-5149Check Rates
3900 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Read Reviews
  • Midscale Suburban hotel
  • Check-in: 3:00PM
~25.70 Miles from Cairo
Pear Tree Inn Paducah
+1-800-230-4134Check Rates
5006 Hinkleville Rd., Paducah, KY 42001
  • 4.0/5, Very Good Review Score
  • Economical Suburban property
  • Hotel has 2 floors
~25.80 Miles from Cairo
Baymont Inn & Suites Metropolis Il
+1-800-997-5148Check Rates
203 East Front St., Metropolis, IL 62960
  • 3.5/5, Average Read Reviews
  • Low Cost Riverfront property
  • Hotel has 2 meeting rooms
~26.33 Miles from Cairo
Baymont Inn Paducah
+1-800-997-5149Check Rates
5300 Cairo Rd., Paducah, KY 42001~27.68 Miles from Cairo
Comfort Suites of Paducah in Paducah
+1-800-230-4134Check Rates
2880 James Sanders Blvd., Paducah, KY 42001
  • 4.0/5, Very Good Reviews
  • Affordable hotel
  • 59 sleeping rooms in hotel
~27.72 Miles from Cairo
Drury Suites Paducah : 2930 James Sanders Blvd.
+1-800-997-5148Check Rates
2930 James Sanders Blvd., Paducah, KY 42001
  • 4.5/5, Very Good Reviews
  • Affordable Suburban property
  • Check in time: 3:00 PM
~27.73 Miles from Cairo
Country Inn & Suites - Paducah
+1-800-997-5149Check Rates
145 Mcbride Lane, Paducah, KY 42001
  • 4.5/5, Very Good Recent Reviews
  • Affordable Highway hotel
  • Gym is available on property
~27.83 Miles from Cairo
Thrifty Inn
+1-800-230-4134Check Rates
5004 Hinkleville Rd., Paducah, KY 42001
  • Two star property
  • 4 floors in hotel
~27.85 Miles from Cairo
Candlewood Suites
+1-800-997-5148Check Rates
3940 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Guest Reviews
  • Cheap Rural property
  • Check in time: 3:00pm
~27.94 Miles from Cairo
Photo of Comfort Inn PaducahComfort Inn Paducah
+1-800-997-5149Check Rates
5135 Old Cairo Rd., Paducah, KY 42001 Website~28.01 Miles from Cairo
Econo Lodge Paducah - Paducah
+1-800-230-4134Check Rates
5106 Old Cairo Rd., Paducah, KY 42001~28.01 Miles from Cairo
Fairfield Inn & Suites in Paducah
+1-800-997-5148Check Rates
3950 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Recent Reviews
  • Affordable Rural hotel
  • 82 sleeping rooms in hotel
~28.03 Miles from Cairo

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