Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.


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Cairo Hotels/Motels & Accommodations

Photo of Eagle InnEagle Inn : 2811 East Marshall St.
+1-800-230-4134Check Rates
2811 East Marshall St., Charleston, MO 63834~9.29 Miles from Cairo
Exterior of Super 8Super 8 in Charleston
+1-800-997-5148Check Rates
310 South Story, Charleston, MO 63834~10.14 Miles from Cairo
Image of Quality InnQuality Inn in Charleston
+1-800-997-5149Check Rates
102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Review Score
  • 2 star Highway property
  • 2 floors in hotel
~11.82 Miles from Cairo
Photo of Best Western Plus SikestonBest Western Plus Sikeston : 120 South Interstate Dr.
+1-800-230-4134Check Rates
120 South Interstate Dr., Sikeston, MO 63801
  • 2-star Highway hotel
  • 2 floors in hotel
~20.97 Miles from Cairo
Exterior of Comfort Inn & SuitesComfort Inn & Suites - Sikeston
+1-800-997-5148Check Rates
109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Reviews
  • Affordable Highway property
  • 17 suites in property
~21.36 Miles from Cairo
Photo of Super 8Super 8
+1-800-997-5149Check Rates
2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Recent Reviews
  • Low priced Convention Center property
  • 62 rooms in hotel
~21.42 Miles from Cairo
Image of Drury Inn & Suites SikestonDrury Inn & Suites Sikeston
+1-800-230-4134Check Rates
2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Guest Reviews
  • Affordable Highway hotel
  • 5 floors in hotel
~21.42 Miles from Cairo
Image of Pear Tree Inn SikestonPear Tree Inn Sikeston
+1-800-997-5148Check Rates
2602 East Malone, Sikeston, MO 63801
  • 3 star Suburban hotel
  • 80 rooms in hotel
~21.42 Miles from Cairo
Residence Inn - Paducah
+1-800-997-5149Check Rates
3900 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Latest Reviews
  • Affordable Suburban property
  • Hotel has 74 suites
~25.70 Miles from Cairo
Pear Tree Inn Paducah : 5006 Hinkleville Rd.
+1-800-230-4134Check Rates
5006 Hinkleville Rd., Paducah, KY 42001
  • 4.0/5, Very Good Reviews
  • 2 star Suburban hotel
  • 2 floors in hotel
~25.80 Miles from Cairo
Baymont Inn & Suites Metropolis Il
+1-800-997-5148Check Rates
203 East Front St., Metropolis, IL 62960
  • 3.5/5, Average Read Reviews
  • Low-priced Riverfront hotel
  • Check in time: 3:00PM
~26.33 Miles from Cairo
Baymont Inn Paducah
+1-800-997-5149Check Rates
5300 Cairo Rd., Paducah, KY 42001~27.68 Miles from Cairo
Comfort Suites of Paducah - Paducah
+1-800-230-4134Check Rates
2880 James Sanders Blvd., Paducah, KY 42001~27.72 Miles from Cairo
Drury Suites Paducah
+1-800-997-5148Check Rates
2930 James Sanders Blvd., Paducah, KY 42001
  • 4.5/5, Very Good Read Reviews
  • Three Star Suburban property
  • Hotel has 6 floors
~27.73 Miles from Cairo
Country Inn & Suites : 145 Mcbride Lane
+1-800-997-5149Check Rates
145 Mcbride Lane, Paducah, KY 42001
  • 4.5/5, Very Good Recent Reviews
  • Mid-scale Highway property
  • Fitness + Health Center
~27.83 Miles from Cairo
Thrifty Inn - Paducah
+1-800-230-4134Check Rates
5004 Hinkleville Rd., Paducah, KY 42001
  • Inexpensive hotel
  • 124 rooms in property
~27.85 Miles from Cairo
La Quinta Inn & Suites
+1-800-997-5148Check Rates
3960 Coleman Crossing Circle, Paducah, KY 42001
  • Midscale hotel
~27.93 Miles from Cairo
Candlewood Suites - Paducah
+1-800-997-5149Check Rates
3940 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Review Score
  • Low priced Rural hotel
  • 85 rooms in property
~27.94 Miles from Cairo
Photo of Comfort Inn PaducahComfort Inn Paducah
+1-800-230-4134Check Rates
5135 Old Cairo Rd., Paducah, KY 42001 Website~28.01 Miles from Cairo
Econo Lodge Paducah - Paducah
+1-800-997-5148Check Rates
5106 Old Cairo Rd., Paducah, KY 42001~28.01 Miles from Cairo

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