Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.


Find my perfect hotel Rooms Check-In Check-Out  
Show Calendar Show Calendar Start My Search >
(select the discounts you qualify for)
Star Rating




Hotel Name

Price Range (USD)
to
Amenities







Set My Filter

Cairo Hotels/Motels & Accommodations

Photo of Eagle InnEagle Inn in Charleston
+1-800-230-4134Check Rates
2811 East Marshall St., Charleston, MO 63834
  • 3.5/5, Average Reviews
  • 2-star hotel
  • Hotel has 19 rooms
~9.29 Miles from Cairo
Photo of Super 8Super 8
+1-800-997-5148Check Rates
310 South Story, Charleston, MO 63834
  • 3.5/5, Average Read Reviews
  • Inexpensive Highway property
  • Free comp. breakfast
~10.14 Miles from Cairo
Image of Quality InnQuality Inn in Charleston
+1-800-997-5149Check Rates
102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Hotel Reviews
  • Economical Highway property
  • 40 rooms in hotel
~11.82 Miles from Cairo
Exterior of Best Western Plus SikestonBest Western Plus Sikeston : 120 South Interstate Dr.
+1-800-230-4134Check Rates
120 South Interstate Dr., Sikeston, MO 63801
  • 2-star Highway hotel
  • Free comp. breakfast
~20.97 Miles from Cairo
Photo of Comfort Inn & SuitesComfort Inn & Suites - Sikeston
+1-800-997-5148Check Rates
109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Reviews
  • 3-star Highway property
  • Gym / Fitness Center Available
~21.36 Miles from Cairo
Image of Drury Inn & Suites SikestonDrury Inn & Suites Sikeston : 2608 East Malone Ave.
+1-800-997-5149Check Rates
2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very good Guest Reviews
  • Three Star Highway hotel
  • 14 suites in hotel
~21.42 Miles from Cairo
Photo of Super 8Super 8 - Sikeston
+1-800-230-4134Check Rates
2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Latest Reviews
  • 2 star Convention Center property
  • Check in: 01:00
~21.42 Miles from Cairo
Photo of Pear Tree Inn SikestonPear Tree Inn Sikeston
+1-800-997-5148Check Rates
2602 East Malone, Sikeston, MO 63801
  • Mid-scale Suburban hotel
  • 4 floors in property
~21.42 Miles from Cairo
Residence Inn in Paducah
+1-800-997-5149Check Rates
3900 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very good Recent Reviews
  • Affordable Suburban hotel
  • Fitness / Gym is on-site
~25.70 Miles from Cairo
Pear Tree Inn Paducah
+1-800-230-4134Check Rates
5006 Hinkleville Rd., Paducah, KY 42001
  • 4.0/5, Very good Reviews
  • Economical Suburban property
  • Check in time: 3:00 PM
~25.80 Miles from Cairo
Baymont Inn & Suites Metropolis Il
+1-800-997-5148Check Rates
203 East Front St., Metropolis, IL 62960
  • 3.0/5, Average Latest Reviews
  • Low priced Riverfront hotel
  • Free breakfast
~26.33 Miles from Cairo
Comfort Suites of Paducah : 2880 James Sanders Blvd.
+1-800-997-5149Check Rates
2880 James Sanders Blvd., Paducah, KY 42001~27.72 Miles from Cairo
Drury Suites Paducah
+1-800-230-4134Check Rates
2930 James Sanders Blvd., Paducah, KY 42001
  • 4.5/5, Very good Hotel Reviews
  • Three Star Suburban property
  • Hotel has 142 rooms
~27.73 Miles from Cairo
Country Inn & Suites : 145 Mcbride Lane
+1-800-997-5148Check Rates
145 Mcbride Lane, Paducah, KY 42001
  • 4.0/5, Very good Guest Reviews
  • Affordable Highway hotel
  • Gym / Fitness Center Available
~27.83 Miles from Cairo
La Quinta Inn & Suites
+1-800-997-5149Check Rates
3960 Coleman Crossing Circle, Paducah, KY 42001
  • Mid-scale Highway property
  • Fitness center on property
~27.93 Miles from Cairo
Candlewood Suites - Paducah
+1-800-230-4134Check Rates
3940 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very good Read Reviews
  • Economy Rural property
  • 85 sleeping rooms in hotel
~27.94 Miles from Cairo
Image of Comfort Inn PaducahComfort Inn Paducah in Paducah
+1-800-997-5148Check Rates
5135 Old Cairo Rd., Paducah, KY 42001 Website~28.01 Miles from Cairo
Econo Lodge Paducah in Paducah
+1-800-997-5149Check Rates
5106 Old Cairo Rd., Paducah, KY 42001~28.01 Miles from Cairo
Fairfield Inn & Suites - Paducah
+1-800-230-4134Check Rates
3950 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very good Reviews
  • Affordable Rural hotel
  • 4 floors in property
~28.03 Miles from Cairo
Hampton Inn & Suites : 3901 Coleman Crossing Circle
+1-800-997-5148Check Rates
3901 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very good Reviews
  • Midscale Highway property
  • Free breakfast
~28.08 Miles from Cairo

 [1 - 20 of 40]   


Next: See My Cairo Hotels with Pricing >