HOTELS in Cairo (Illinois)

Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.


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Cairo Hotels/Accommodations

Image of Eagle Inn Eagle Inn
+1-800-230-4134Check Rates
2811 East Marshall St., Charleston, MO 63834
  • 3.5/5, Average Guest Reviews
  • Economical property
  • 19 rooms in hotel
~9.29 Miles from Cairo
Exterior of Super 8 Super 8 : 310 South Story
+1-800-997-5148Check Rates
310 South Story, Charleston, MO 63834
  • 3.0/5, Average Review Score
  • 2-star Highway hotel
  • Check-in time: 3:00pm
~10.14 Miles from Cairo
Photo of Quality Inn Quality Inn
+1-800-997-5149Check Rates
102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Hotel Reviews
  • Two-star Highway hotel
  • Hotel has 40 rooms
~11.82 Miles from Cairo
Photo of Best Western Plus Sikeston Best Western Plus Sikeston
+1-800-230-4134Check Rates
120 South Interstate Dr., Sikeston, MO 63801
  • Two star Highway hotel
  • Fitness + Health Center
~20.97 Miles from Cairo
Exterior of Comfort Inn & Suites Comfort Inn & Suites
+1-800-997-5148Check Rates
109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Hotel Reviews
  • Three Star Highway property
  • 64 rooms in property
~21.36 Miles from Cairo
Image of Super 8 Super 8 in Sikeston
+1-800-997-5149Check Rates
2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Guest Reviews
  • Cheap Convention Center hotel
  • 62 rooms in property
~21.42 Miles from Cairo
Photo of Drury Inn & Suites Sikeston Drury Inn & Suites Sikeston - Sikeston
+1-800-230-4134Check Rates
2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Hotel Reviews
  • 3-star Highway hotel
  • 154 sleeping rooms in hotel
~21.42 Miles from Cairo
Photo of Pear Tree Inn Sikeston Pear Tree Inn Sikeston in Sikeston
+1-800-997-5148Check Rates
2602 East Malone, Sikeston, MO 63801
  • Affordable Suburban property
  • 80 rooms in hotel
~21.42 Miles from Cairo
Residence Inn in Paducah
+1-800-997-5149Check Rates
3900 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Reviews
  • Midscale Suburban property
  • Check-in time: 3:00PM
~25.70 Miles from Cairo
Pear Tree Inn Paducah
+1-800-230-4134Check Rates
5006 Hinkleville Rd., Paducah, KY 42001
  • 4.0/5, Very Good Review Score
  • Economical Suburban hotel
  • Free breakfast
~25.80 Miles from Cairo
Baymont Inn & Suites Metropolis Il
+1-800-997-5148Check Rates
203 East Front St., Metropolis, IL 62960
  • 3.5/5, Average Reviews
  • Two-star Riverfront hotel
  • 2 floors in property
~26.33 Miles from Cairo
Baymont Inn Paducah
+1-800-997-5149Check Rates
5300 Cairo Rd., Paducah, KY 42001
  • 3.0/5, Average Reviews
  • Mid-scale hotel
~27.68 Miles from Cairo
Comfort Suites of Paducah in Paducah
+1-800-230-4134Check Rates
2880 James Sanders Blvd., Paducah, KY 42001
  • 4.0/5, Very Good Latest Reviews
  • Affordable hotel
  • Hotel has 59 suites
~27.72 Miles from Cairo
Drury Suites Paducah
+1-800-997-5148Check Rates
2930 James Sanders Blvd., Paducah, KY 42001
  • 4.5/5, Very Good Recent Reviews
  • 3 star Suburban property
  • Gym is available on property
~27.73 Miles from Cairo
Country Inn & Suites - Paducah
+1-800-997-5149Check Rates
145 Mcbride Lane, Paducah, KY 42001
  • 4.5/5, Very Good Latest Reviews
  • 3-star Highway hotel
  • Fitness / Gym is on-site
~27.83 Miles from Cairo
Thrifty Inn : 5004 Hinkleville Rd.
+1-800-230-4134Check Rates
5004 Hinkleville Rd., Paducah, KY 42001
  • Two star property
  • 124 rooms in property
~27.85 Miles from Cairo
Candlewood Suites in Paducah
+1-800-997-5148Check Rates
3940 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Recent Reviews
  • Cheap Rural hotel
  • 85 sleeping rooms in hotel
~27.94 Miles from Cairo
Image of Comfort Inn Paducah Comfort Inn Paducah
+1-800-997-5149Check Rates
5135 Old Cairo Rd., Paducah, KY 42001 Website
  • 4.0/5, Very Good Latest Reviews
  • Economy property
  • Gym is available on property
~28.01 Miles from Cairo
Econo Lodge Paducah
+1-800-230-4134Check Rates
5106 Old Cairo Rd., Paducah, KY 42001 ~28.01 Miles from Cairo
Fairfield Inn & Suites
+1-800-997-5148Check Rates
3950 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Guest Reviews
  • 3 star Rural hotel
  • Hotel has 4 floors
~28.03 Miles from Cairo

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