Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.


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Cairo Hotels & Accommodations

Exterior of Eagle InnEagle Inn
+1-800-230-4134Check Rates
2811 East Marshall St., Charleston, MO 63834
  • 3.5/5, Average Reviews
  • 2 star property
  • Fitness / Gym is on-site
~9.29 Miles from Cairo
Image of Super 8Super 8 in Charleston
+1-800-997-5148Check Rates
310 South Story, Charleston, MO 63834
  • 3.5/5, Average Latest Reviews
  • 2-star Highway property
  • Free breakfast available
~10.14 Miles from Cairo
Photo of Quality InnQuality Inn - Charleston
+1-800-997-5149Check Rates
102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Reviews
  • Inexpensive Highway hotel
  • 9 suites in hotel
~11.82 Miles from Cairo
Exterior of Best Western Plus SikestonBest Western Plus Sikeston
+1-800-230-4134Check Rates
120 South Interstate Dr., Sikeston, MO 63801
  • Two-star Highway hotel
  • Fitness center on property
~20.97 Miles from Cairo
Exterior of Comfort Inn & SuitesComfort Inn & Suites
+1-800-997-5148Check Rates
109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Hotel Reviews
  • 3 star Highway property
  • Comp. Breakfast
~21.36 Miles from Cairo
Exterior of Drury Inn & Suites SikestonDrury Inn & Suites Sikeston
+1-800-997-5149Check Rates
2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Hotel Reviews
  • Three Star Highway property
  • 154 rooms in hotel
~21.42 Miles from Cairo
Exterior of Super 8Super 8 - Sikeston
+1-800-230-4134Check Rates
2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Recent Reviews
  • Two-star Convention Center hotel
  • Check-in time: 01:00
~21.42 Miles from Cairo
Image of Pear Tree Inn SikestonPear Tree Inn Sikeston
+1-800-997-5148Check Rates
2602 East Malone, Sikeston, MO 63801
  • 3 star Suburban hotel
  • 2 suites in hotel
~21.42 Miles from Cairo
Residence Inn
+1-800-997-5149Check Rates
3900 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Reviews
  • Three Star Suburban hotel
  • Free breakfast
~25.70 Miles from Cairo
Pear Tree Inn Paducah in Paducah
+1-800-230-4134Check Rates
5006 Hinkleville Rd., Paducah, KY 42001
  • 4.0/5, Very Good Recent Reviews
  • Low-priced Suburban hotel
  • Hotel has 2 floors
~25.80 Miles from Cairo
Baymont Inn & Suites Metropolis Il : 203 East Front St.
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203 East Front St., Metropolis, IL 62960
  • 3.0/5, Average Recent Reviews
  • Low priced Riverfront property
  • Free breakfast
~26.33 Miles from Cairo
Comfort Suites of Paducah
+1-800-997-5149Check Rates
2880 James Sanders Blvd., Paducah, KY 42001
  • 4.0/5, Very Good Latest Reviews
  • Affordable hotel
  • Fitness center on property
~27.72 Miles from Cairo
Drury Suites Paducah
+1-800-230-4134Check Rates
2930 James Sanders Blvd., Paducah, KY 42001
  • 4.5/5, Very Good Reviews
  • Three Star Suburban hotel
  • Hotel has 6 floors
~27.73 Miles from Cairo
Country Inn & Suites - Paducah
+1-800-997-5148Check Rates
145 Mcbride Lane, Paducah, KY 42001
  • 4.5/5, Very Good Reviews
  • Mid-scale Highway property
  • 3 floors in property
~27.83 Miles from Cairo
La Quinta Inn & Suites
+1-800-997-5149Check Rates
3960 Coleman Crossing Circle, Paducah, KY 42001
  • Three Star Highway hotel
  • 77 rooms in property
~27.93 Miles from Cairo
Candlewood Suites in Paducah
+1-800-230-4134Check Rates
3940 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Latest Reviews
  • Economical Rural property
  • 4 floors in property
~27.94 Miles from Cairo
Photo of Comfort Inn PaducahComfort Inn Paducah
+1-800-997-5148Check Rates
5135 Old Cairo Rd., Paducah, KY 42001 Website
  • 4.5/5, Very Good Read Reviews
  • Low Cost hotel
  • 64 suites in hotel
~28.01 Miles from Cairo
Econo Lodge Paducah : 5106 Old Cairo Rd.
+1-800-997-5149Check Rates
5106 Old Cairo Rd., Paducah, KY 42001~28.01 Miles from Cairo
Fairfield Inn & Suites
+1-800-230-4134Check Rates
3950 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Recent Reviews
  • Mid-scale Rural property
  • Hotel has 82 rooms
~28.03 Miles from Cairo
Hampton Inn & Suites in Paducah
+1-800-997-5148Check Rates
3901 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Review Score
  • Mid-scale Highway property
  • 4 floors in property
~28.08 Miles from Cairo

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