Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.


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Cairo Hotels/Motels & Accommodations

Image of Eagle InnEagle Inn
+1-800-230-4134Check Rates
2811 East Marshall St., Charleston, MO 63834
  • 3.5/5, Average Reviews
  • Cheap property
  • Gym is available on property
~9.29 Miles from Cairo
Exterior of Super 8Super 8 : 310 South Story
+1-800-997-5148Check Rates
310 South Story, Charleston, MO 63834
  • 3.5/5, Average Guest Reviews
  • Cheap Highway property
  • Free breakfast available
~10.14 Miles from Cairo
Image of Quality InnQuality Inn
+1-800-997-5149Check Rates
102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Latest Reviews
  • 2-star Highway property
  • Fitness / Gym is on-site
~11.82 Miles from Cairo
Photo of Best Western Plus SikestonBest Western Plus Sikeston in Sikeston
+1-800-230-4134Check Rates
120 South Interstate Dr., Sikeston, MO 63801
  • Low priced Highway property
  • Check-in time: 11:00AM
~20.97 Miles from Cairo
Image of Comfort Inn & SuitesComfort Inn & Suites
+1-800-997-5148Check Rates
109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Hotel Reviews
  • Midscale Highway property
  • Comp. Breakfast
~21.36 Miles from Cairo
Exterior of Drury Inn & Suites SikestonDrury Inn & Suites Sikeston - Sikeston
+1-800-997-5149Check Rates
2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Review Score
  • Mid-scale Highway hotel
  • Hotel has 4 meeting rooms
~21.42 Miles from Cairo
Photo of Super 8Super 8 in Sikeston
+1-800-230-4134Check Rates
2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Review Score
  • Economical Convention Center property
  • Check in: 01:00
~21.42 Miles from Cairo
Image of Pear Tree Inn SikestonPear Tree Inn Sikeston : 2602 East Malone
+1-800-997-5148Check Rates
2602 East Malone, Sikeston, MO 63801
  • 3-star Suburban property
  • 80 rooms in property
~21.42 Miles from Cairo
Residence Inn : 3900 Coleman Crossing Circle
+1-800-997-5149Check Rates
3900 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Latest Reviews
  • Midscale Suburban hotel
  • Hotel has 74 rooms
~25.70 Miles from Cairo
Pear Tree Inn Paducah
+1-800-230-4134Check Rates
5006 Hinkleville Rd., Paducah, KY 42001
  • 4.0/5, Very Good Read Reviews
  • Cheap Suburban property
  • 60 rooms in property
~25.80 Miles from Cairo
Baymont Inn & Suites Metropolis Il : 203 East Front St.
+1-800-997-5148Check Rates
203 East Front St., Metropolis, IL 62960
  • 3.5/5, Average Read Reviews
  • Economy Riverfront hotel
  • Hotel has 2 floors
~26.33 Miles from Cairo
Baymont Inn Paducah in Paducah
+1-800-997-5149Check Rates
5300 Cairo Rd., Paducah, KY 42001~27.68 Miles from Cairo
Comfort Suites of Paducah
+1-800-230-4134Check Rates
2880 James Sanders Blvd., Paducah, KY 42001~27.72 Miles from Cairo
Drury Suites Paducah
+1-800-997-5148Check Rates
2930 James Sanders Blvd., Paducah, KY 42001
  • 4.5/5, Very Good Reviews
  • 3 star Suburban property
  • 2 meeting rooms in hotel
~27.73 Miles from Cairo
Country Inn & Suites in Paducah
+1-800-997-5149Check Rates
145 Mcbride Lane, Paducah, KY 42001
  • 4.5/5, Very Good Read Reviews
  • Midscale Highway property
  • Comp. Breakfast
~27.83 Miles from Cairo
Thrifty Inn - Paducah
+1-800-230-4134Check Rates
5004 Hinkleville Rd., Paducah, KY 42001
  • Economical property
  • Hotel has 124 rooms
~27.85 Miles from Cairo
La Quinta Inn & Suites in Paducah
+1-800-997-5148Check Rates
3960 Coleman Crossing Circle, Paducah, KY 42001
  • Midscale Highway property
  • Hotel has an eco-friendly policy Learn more
~27.93 Miles from Cairo
Candlewood Suites - Paducah
+1-800-997-5149Check Rates
3940 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Recent Reviews
  • Two star Rural property
  • Check-in: 3:00pm
~27.94 Miles from Cairo
Photo of Comfort Inn PaducahComfort Inn Paducah in Paducah
+1-800-230-4134Check Rates
5135 Old Cairo Rd., Paducah, KY 42001 Website~28.01 Miles from Cairo
Econo Lodge Paducah
+1-800-997-5148Check Rates
5106 Old Cairo Rd., Paducah, KY 42001
  • 3.0/5, Average Reviews
  • Cheap property
~28.01 Miles from Cairo

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