Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates


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Charleston Hotels, Motels & Accommodations

Photo of Super 8Super 8 in Charleston
+1-800-230-4134Check Rates
310 South Story, Charleston, MO 63834
  • 3.0/5, Average Hotel Reviews
  • Economy Highway hotel
  • Free breakfast available
Photo of Quality InnQuality Inn : 102 Drake St.
+1-800-997-5148Check Rates
102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Guest Reviews
  • Inexpensive Highway hotel
  • 9 suites in property
Photo of Eagle InnEagle Inn
+1-800-997-5149Check Rates
2811 East Marshall St., Charleston, MO 63834
  • 3.5/5, Average Guest Reviews
  • Two-star property
  • Access to gym on-site
Photo of Best Western Plus SikestonBest Western Plus Sikeston
+1-800-230-4134Check Rates
120 South Interstate Dr., Sikeston, MO 63801
  • Two star Highway hotel
  • Hotel has 2 floors
~11.00 Miles from Charleston
Exterior of Comfort Inn & SuitesComfort Inn & Suites
+1-800-997-5148Check Rates
109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Reviews
  • 3 star Highway hotel
  • Hotel has 17 suites
~11.37 Miles from Charleston
Photo of Drury Inn & Suites SikestonDrury Inn & Suites Sikeston in Sikeston
+1-800-997-5149Check Rates
2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Review Score
  • Midscale Highway property
  • Hotel has 14 suites
~11.45 Miles from Charleston
Image of Super 8Super 8
+1-800-230-4134Check Rates
2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Read Reviews
  • Low Cost Convention Center property
  • Hotel has 2 floors
~11.45 Miles from Charleston
Image of Pear Tree Inn SikestonPear Tree Inn Sikeston
+1-800-997-5148Check Rates
2602 East Malone, Sikeston, MO 63801
  • Mid-scale Suburban property
  • Fitness / Gym is on-site
~11.45 Miles from Charleston
Candlewood Suites Cape Girardeau - Cape Girardeau
+1-800-997-5149Check Rates
485 South Mount Auburn Rd., Cape Girardeau, MO 65703
  • 4.0/5, Very Good Guest Reviews
  • Low-priced Highway hotel
  • 85 suites in hotel
~28.61 Miles from Charleston
Victorian Inn & Suites - Cape Girardeau
+1-800-230-4134Check Rates
3256 William St., Cape Girardeau, MO 63703
  • 3-star Golf Course hotel
  • Comp. Breakfast
~29.40 Miles from Charleston
Auburn Place Hotel & Suites
+1-800-997-5148Check Rates
3265 Williams St., Cape Girardeau, MO 63702
  • 4.0/5, Very Good Guest Reviews
  • 3-star Highway property
  • Check-in: 0300 pm
~29.41 Miles from Charleston
Holiday Inn Express Hotel & Suites
+1-800-997-5149Check Rates
3253 William St., Cape Girardeau, MO 63701
  • 4.5/5, Very Good Guest Reviews
  • Mid-scale hotel
  • 3 meeting rooms in property
~29.49 Miles from Charleston
Pear Tree Inn Cape Girardeau
+1-800-230-4134Check Rates
3248 William St., Cape Girardeau, MO 63701
  • Two star Highway hotel
  • Check in: 3:00 pm
~29.50 Miles from Charleston
Drury Suites Cape Girardeau
+1-800-997-5148Check Rates
3303 Campster Dr., Cape Girardeau, MO 63701
  • 4.5/5, Very Good Hotel Reviews
  • 3-star Highway property
  • Free breakfast available
~29.60 Miles from Charleston
Drury Lodge Cape Girardeau
+1-800-997-5149Check Rates
104 South Vantage Dr., Cape Girardeau, MO 63701
  • 3 star Highway property
  • Access to gym on-site
~29.76 Miles from Charleston
Photo of Comfort Suites Jackson / Cape GirardeauComfort Suites Jackson / Cape Girardeau
+1-800-230-4134Check Rates
2904 Old Orchard Rd., Jackson, MO 63755 Website
  • 4.0/5, Very Good Recent Reviews
  • Midscale Highway property
  • Gym is available on property
~33.57 Miles from Charleston
Residence Inn
+1-800-997-5148Check Rates
3900 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Review Score
  • Mid-scale Suburban property
  • Gym is available on property
~34.97 Miles from Charleston
Pear Tree Inn Paducah
+1-800-997-5149Check Rates
5006 Hinkleville Rd., Paducah, KY 42001
  • 4.0/5, Very Good Review Score
  • Low-priced Suburban hotel
  • 2 floors in property
~35.47 Miles from Charleston
Econo Lodge Dexter - Dexter
+1-800-230-4134Check Rates
913 Outer Rd., Dexter, MO 63841~36.06 Miles from Charleston
Baymont Inn & Suites Metropolis Il in Metropolis
+1-800-997-5148Check Rates
203 East Front St., Metropolis, IL 62960
  • 3.5/5, Average Hotel Reviews
  • Economy Riverfront property
  • 120 rooms in property
~36.55 Miles from Charleston

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