Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates


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Charleston Hotels/Motels & Accommodations

Exterior of Super 8Super 8 - Charleston
+1-800-230-4134Check Rates
310 South Story, Charleston, MO 63834
Photo of Quality InnQuality Inn - Charleston
+1-800-997-5148Check Rates
102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Recent Reviews
  • Two star Highway property
  • Gym is available on property
Exterior of Eagle InnEagle Inn
+1-800-997-5149Check Rates
2811 East Marshall St., Charleston, MO 63834
Exterior of Best Western Plus SikestonBest Western Plus Sikeston
+1-800-230-4134Check Rates
120 South Interstate Dr., Sikeston, MO 63801
  • 2 star Highway property
  • Fitness / Gym is on-site
~11.00 Miles from Charleston
Photo of Comfort Inn & SuitesComfort Inn & Suites - Sikeston
+1-800-997-5148Check Rates
109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Guest Reviews
  • Affordable Highway hotel
  • Check in time: 02:00 PM
~11.37 Miles from Charleston
Exterior of Drury Inn & Suites SikestonDrury Inn & Suites Sikeston
+1-800-997-5149Check Rates
2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Review Score
  • Three Star Highway hotel
  • Check-in: 3:00 PM
~11.45 Miles from Charleston
Exterior of Super 8Super 8
+1-800-230-4134Check Rates
2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Read Reviews
  • 2 star Convention Center hotel
  • 62 sleeping rooms in hotel
~11.45 Miles from Charleston
Photo of Pear Tree Inn SikestonPear Tree Inn Sikeston : 2602 East Malone
+1-800-997-5148Check Rates
2602 East Malone, Sikeston, MO 63801
  • Mid-scale Suburban property
  • Check-in: 3:00 PM
~11.45 Miles from Charleston
Candlewood Suites Cape Girardeau in Cape Girardeau
+1-800-997-5149Check Rates
485 South Mount Auburn Rd., Cape Girardeau, MO 65703
  • 4.0/5, Very Good Reviews
  • Cheap Highway hotel
  • Fitness center on property
~28.61 Miles from Charleston
Victorian Inn & Suites in Cape Girardeau
+1-800-230-4134Check Rates
3256 William St., Cape Girardeau, MO 63703
  • Midscale Golf Course property
  • Free breakfast available
~29.40 Miles from Charleston
Auburn Place Hotel & Suites : 3265 Williams St.
+1-800-997-5148Check Rates
3265 Williams St., Cape Girardeau, MO 63702
  • 4.0/5, Very Good Latest Reviews
  • 3 star Highway property
  • Hotel has 133 rooms
~29.41 Miles from Charleston
Holiday Inn Express Hotel & Suites in Cape Girardeau
+1-800-997-5149Check Rates
3253 William St., Cape Girardeau, MO 63701
  • 4.5/5, Very Good Review Score
  • 3 star hotel
  • 3 meeting rooms in property
~29.49 Miles from Charleston
Pear Tree Inn Cape Girardeau : 3248 William St.
+1-800-230-4134Check Rates
3248 William St., Cape Girardeau, MO 63701
  • 2 star Highway property
  • Check in time: 3:00 pm
~29.50 Miles from Charleston
Drury Suites Cape Girardeau : 3303 Campster Dr.
+1-800-997-5148Check Rates
3303 Campster Dr., Cape Girardeau, MO 63701
  • 4.5/5, Very Good Read Reviews
  • Mid-scale Highway hotel
  • 87 rooms in property
~29.60 Miles from Charleston
Drury Lodge Cape Girardeau in Cape Girardeau
+1-800-997-5149Check Rates
104 South Vantage Dr., Cape Girardeau, MO 63701
  • 3-star Highway hotel
  • Fitness center on property
~29.76 Miles from Charleston
Photo of Comfort Suites Jackson / Cape GirardeauComfort Suites Jackson / Cape Girardeau : 2904 Old Orchard Rd.
+1-800-230-4134Check Rates
2904 Old Orchard Rd., Jackson, MO 63755 Website
  • 4.0/5, Very Good Guest Reviews
  • Affordable Highway property
  • Complimentary breakfast is offered
~33.57 Miles from Charleston
Residence Inn - Paducah
+1-800-997-5148Check Rates
3900 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Reviews
  • 3 star Suburban property
  • 74 suites in hotel
~34.97 Miles from Charleston
Pear Tree Inn Paducah - Paducah
+1-800-997-5149Check Rates
5006 Hinkleville Rd., Paducah, KY 42001
  • 4.0/5, Very Good Latest Reviews
  • Cheap Suburban property
  • Check in time: 3:00 PM
~35.47 Miles from Charleston
Econo Lodge Dexter in Dexter
+1-800-230-4134Check Rates
913 Outer Rd., Dexter, MO 63841
  • 3.5/5, Average Hotel Reviews
  • Economical property
  • Complimentary breakfast is offered
~36.06 Miles from Charleston
Baymont Inn & Suites Metropolis Il
+1-800-997-5148Check Rates
203 East Front St., Metropolis, IL 62960
  • 3.0/5, Average Review Score
  • Low-priced Riverfront property
  • 120 rooms in hotel
~36.55 Miles from Charleston

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