Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates


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Charleston Hotels, Motels & Accommodations

Image of Super 8 Super 8
+1-800-230-4134Check Rates
310 South Story, Charleston, MO 63834
  • 3.5/5, Average Guest Reviews
  • Inexpensive Highway property
  • Free breakfast
Exterior of Quality Inn Quality Inn - Charleston
+1-800-997-5148Check Rates
102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Read Reviews
  • 2-star Highway property
  • Check-in: 3:00PM
Photo of Eagle Inn Eagle Inn
+1-800-997-5149Check Rates
2811 East Marshall St., Charleston, MO 63834
  • 3.5/5, Average Guest Reviews
  • Inexpensive hotel
  • 19 rooms in property
Photo of Best Western Plus Sikeston Best Western Plus Sikeston
+1-800-230-4134Check Rates
120 South Interstate Dr., Sikeston, MO 63801
  • 2 star Highway property
  • 55 rooms in hotel
~11.00 Miles from Charleston
Image of Comfort Inn & Suites Comfort Inn & Suites : 109 Matthews Lane
+1-800-997-5148Check Rates
109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Read Reviews
  • 3 star Highway hotel
  • Fitness + Health Center
~11.37 Miles from Charleston
Exterior of Super 8 Super 8
+1-800-997-5149Check Rates
2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Guest Reviews
  • Economy Convention Center property
  • 2 floors in hotel
~11.45 Miles from Charleston
Image of Drury Inn & Suites Sikeston Drury Inn & Suites Sikeston in Sikeston
+1-800-230-4134Check Rates
2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Latest Reviews
  • 3-star Highway property
  • Free complimentary breakfast
~11.45 Miles from Charleston
Photo of Pear Tree Inn Sikeston Pear Tree Inn Sikeston
+1-800-997-5148Check Rates
2602 East Malone, Sikeston, MO 63801
  • Midscale Suburban hotel
  • Hotel has 2 suites
~11.45 Miles from Charleston
Candlewood Suites Cape Girardeau - Cape Girardeau
+1-800-997-5149Check Rates
485 South Mount Auburn Rd., Cape Girardeau, MO 65703
  • 4.0/5, Very Good Read Reviews
  • Cheap Highway hotel
  • Hotel has 85 suites
~28.61 Miles from Charleston
Victorian Inn & Suites
+1-800-230-4134Check Rates
3256 William St., Cape Girardeau, MO 63703
  • 3 star Golf Course hotel
  • Check-in: 3:00 pm
~29.40 Miles from Charleston
Auburn Place Hotel & Suites - Cape Girardeau
+1-800-997-5148Check Rates
3265 Williams St., Cape Girardeau, MO 63702
  • 4.0/5, Very Good Recent Reviews
  • Mid-scale Highway hotel
  • 133 rooms in property
~29.41 Miles from Charleston
Holiday Inn Express Hotel & Suites
+1-800-997-5149Check Rates
3253 William St., Cape Girardeau, MO 63701
  • 4.5/5, Very Good Review Score
  • Three Star hotel
  • 10 floors in property
~29.49 Miles from Charleston
Pear Tree Inn Cape Girardeau in Cape Girardeau
+1-800-230-4134Check Rates
3248 William St., Cape Girardeau, MO 63701
  • Economy Highway property
  • 78 sleeping rooms in hotel
~29.50 Miles from Charleston
Drury Suites Cape Girardeau - Cape Girardeau
+1-800-997-5148Check Rates
3303 Campster Dr., Cape Girardeau, MO 63701
  • 4.5/5, Very Good Hotel Reviews
  • Mid-scale Highway property
  • 79 suites in property
~29.60 Miles from Charleston
Drury Lodge Cape Girardeau : 104 South Vantage Dr.
+1-800-997-5149Check Rates
104 South Vantage Dr., Cape Girardeau, MO 63701
  • 3-star Highway property
  • 8 meeting rooms in property
~29.76 Miles from Charleston
Photo of Comfort Suites Jackson / Cape Girardeau Comfort Suites Jackson / Cape Girardeau - Jackson
+1-800-230-4134Check Rates
2904 Old Orchard Rd., Jackson, MO 63755 Website
  • 4.0/5, Very Good Reviews
  • Midscale Highway property
  • 3 floors in property
~33.57 Miles from Charleston
Residence Inn : 3900 Coleman Crossing Circle
+1-800-997-5148Check Rates
3900 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Reviews
  • 3-star Suburban property
  • 74 rooms in property
~34.97 Miles from Charleston
Pear Tree Inn Paducah in Paducah
+1-800-997-5149Check Rates
5006 Hinkleville Rd., Paducah, KY 42001
  • 4.0/5, Very Good Review Score
  • 2-star Suburban hotel
  • Check in time: 3:00 PM
~35.47 Miles from Charleston
Econo Lodge Dexter : 913 Outer Rd.
+1-800-230-4134Check Rates
913 Outer Rd., Dexter, MO 63841 ~36.06 Miles from Charleston
Baymont Inn & Suites Metropolis Il : 203 East Front St.
+1-800-997-5148Check Rates
203 East Front St., Metropolis, IL 62960
  • 3.0/5, Average Guest Reviews
  • Low Cost Riverfront property
  • Check in: 3:00PM
~36.55 Miles from Charleston

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