Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles from Lake Marion Resort and Marina and 18 miles from Edisto Memorial Gardens.

Find my perfect hotel Rooms Check-In Check-Out  
Show Calendar Show Calendar Start My Search >
(select the discounts you qualify for)
Star Rating




Hotel Name

Price Range (USD)
to
Amenities







Set My Filter

Santee Hotels/Accommodations

Days Inn - Santee
+1-800-230-4134Check Rates
9074 Old Highway Six, Santee, SC 29142
  • 2 star property
Photo of Holiday Inn SanteeHoliday Inn Santee
+1-800-997-5148Check Rates
139 Bradford Blvd., Santee, SC 29142
  • 3.0/5, Average Hotel Reviews
  • 3-star Highway hotel
  • Check in time: 4:00pm
Photo of Comfort Inn & SuitesComfort Inn & Suites : 221 Britain St.
+1-800-997-5149Check Rates
221 Britain St., Santee, SC 29142
Exterior of Quality Inn & SuitesQuality Inn & Suites - Santee
+1-800-230-4134Check Rates
8929 Old Number Six Highway, Santee, SC 29142
  • 3.0/5, Average Hotel Reviews
  • 2-star Highway hotel
  • 153 sleeping rooms in hotel
Photo of Howard Johnson SanteeHoward Johnson Santee : 249 Britain St.
+1-800-997-5148Check Rates
249 Britain St., Santee, SC 29142
  • 3.0/5, Average Read Reviews
  • Cheap Golf Course hotel
  • Comp. Breakfast
Exterior of Whitten InnWhitten Inn : 123 Mall St.
+1-800-997-5149Check Rates
123 Mall St., Santee, SC 29142
  • 2.5/5, Poor Read Reviews
  • 2-star Highway hotel
  • Check-in time: 2:00 pm
Hampton Inn Santee I 95 : 9060 Old #6 Highway
+1-800-230-4134Check Rates
9060 Old #6 Highway, Santee, SC 29142
  • 4.5/5, Very Good Hotel Reviews
  • Mid-scale Highway property
  • Hotel has 81 rooms
Photo of Econo Lodge SanteeEcono Lodge Santee in Santee
+1-800-997-5148Check Rates
9112 Old Number 6 Highway, Santee, SC 29142
Rodeway Inn Santee - Santee
+1-800-997-5149Check Rates
9117 Old Number 6 Highway, Santee, SC 29142
  • 3.0/5, Average Review Score
  • Two-star Highway property
  • Free comp. breakfast
Best Western Plus Santee Inn
+1-800-230-4134Check Rates
9059 Old Number Six Highway, Santee, SC 29142
  • Three Star property
Travelodge : 9091 Old Highway 6
+1-800-997-5148Check Rates
9091 Old Highway 6, Santee, SC 29142
  • 3.0/5, Average Latest Reviews
  • 2 star Golf Course property
  • Check in time: 1.00
Peachtree Inn : 111 Conners Dr.
+1-800-997-5149Check Rates
111 Conners Dr., Saint George, SC 29477
  • 4.5/5, Very Good Reviews
  • Midscale Highway hotel
  • 39 rooms in hotel
~15.51 Miles from Santee
Sunset Inn Manning : 5932 Alex Highway
+1-800-230-4134Check Rates
5932 Alex Highway, Manning, SC 29102~16.27 Miles from Santee
Hampton Inn
+1-800-997-5148Check Rates
2822 Paxville Highway, Manning, SC 29102
  • 4.5/5, Very Good Latest Reviews
  • 3 star Highway property
  • Free comp. breakfast
~19.30 Miles from Santee
Quality Inn
+1-800-997-5149Check Rates
3031 Paxville Highway, Manning, SC 29102~19.32 Miles from Santee
Country Inn & Suites : 731 Citadel Rd.
+1-800-230-4134Check Rates
731 Citadel Rd., Orangeburg, SC 29118~19.66 Miles from Santee
Fairfield Inn Orangeburg : 663 Citadel
+1-800-997-5148Check Rates
663 Citadel, Orangeburg, SC 29118~20.28 Miles from Santee
Comfort Inn & Suites
+1-800-997-5149Check Rates
746 Citadel Rd., Orangeburg, SC 29118 Website
  • 4.0/5, Very Good Recent Reviews
  • 2-star Rural hotel
  • 14 suites in property
~20.37 Miles from Santee
Days Inn : 2825 Paxville Highway
+1-800-230-4134Check Rates
2825 Paxville Highway, Manning, SC 29102
  • 2.5/5, Poor Reviews
  • Low priced hotel
~20.47 Miles from Santee
Southern Lodge - Orangeburg
+1-800-997-5148Check Rates
3616 St. Matthews Rd., Orangeburg, SC 29118
  • Low-priced Highway property
  • Hotel has 43 rooms
~20.48 Miles from Santee

 [1 - 20 of 50]   


Next: See My Santee Hotels with Pricing >