HOTELS in Santee

Hotels in Santee SC & Motels in Santee South Carolina

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles from Lake Marion Resort and Marina and 18 miles from Edisto Memorial Gardens.

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Santee Hotels/Motels & Accommodations

Days Inn - Santee
+1-800-230-4134Check Rates
9074 Old Highway Six, Santee, SC 29142
  • Low-priced property
Exterior of Holiday Inn SanteeHoliday Inn Santee in Santee
+1-800-997-5148Check Rates
139 Bradford Blvd., Santee, SC 29142
  • 3.0/5, Average Reviews
  • Three Star Highway property
  • 84 rooms in property
Image of Comfort Inn & SuitesComfort Inn & Suites
+1-800-997-5149Check Rates
221 Britain St., Santee, SC 29142
  • 4.0/5, Very Good Review Score
  • Low priced Lake property
  • Hotel has 3 floors
Image of Quality Inn & SuitesQuality Inn & Suites
+1-800-230-4134Check Rates
8929 Old Number Six Highway, Santee, SC 29142
  • 3.0/5, Average Read Reviews
  • 2 star Highway property
  • Hotel has 153 rooms
Photo of Howard Johnson SanteeHoward Johnson Santee
+1-800-997-5148Check Rates
249 Britain St., Santee, SC 29142
  • 3.5/5, Average Latest Reviews
  • Cheap Golf Course hotel
  • Free comp. breakfast
Image of Whitten InnWhitten Inn in Santee
+1-800-997-5149Check Rates
123 Mall St., Santee, SC 29142
  • 2.5/5, Poor Hotel Reviews
  • Cheap Highway hotel
  • 3 meeting rooms in property
Hampton Inn Santee I 95 : 9060 Old #6 Highway
+1-800-230-4134Check Rates
9060 Old #6 Highway, Santee, SC 29142
  • 4.5/5, Very Good Review Score
  • Three Star Highway property
  • Free comp. breakfast
Photo of Econo Lodge SanteeEcono Lodge Santee
+1-800-997-5148Check Rates
9112 Old Number 6 Highway, Santee, SC 29142
  • 3.5/5, Average Read Reviews
  • Economy Highway property
  • Hotel has 37 rooms
Rodeway Inn Santee
+1-800-997-5149Check Rates
9117 Old Number 6 Highway, Santee, SC 29142
Best Western Plus Santee Inn : 9059 Old Number Six Highway
+1-800-230-4134Check Rates
9059 Old Number Six Highway, Santee, SC 29142
  • Three Star hotel
Travelodge in Santee
+1-800-997-5148Check Rates
9091 Old Highway 6, Santee, SC 29142
  • 3.0/5, Average Hotel Reviews
  • Two-star Golf Course property
  • Check-in: 1.00
Peachtree Inn
+1-800-997-5149Check Rates
111 Conners Dr., Saint George, SC 29477
  • 4.5/5, Very Good Read Reviews
  • Affordable Highway hotel
  • Check in time: 3.00
~15.51 Miles from Santee
Sunset Inn Manning in Manning
+1-800-230-4134Check Rates
5932 Alex Highway, Manning, SC 29102~16.27 Miles from Santee
Hampton Inn
+1-800-997-5148Check Rates
2822 Paxville Highway, Manning, SC 29102
  • 4.5/5, Very Good Guest Reviews
  • 3-star Highway hotel
  • Complimentary breakfast is offered
~19.30 Miles from Santee
Quality Inn : 3031 Paxville Highway
+1-800-997-5149Check Rates
3031 Paxville Highway, Manning, SC 29102~19.32 Miles from Santee
Country Inn & Suites in Orangeburg
+1-800-230-4134Check Rates
731 Citadel Rd., Orangeburg, SC 29118
  • 3.5/5, Average Read Reviews
  • Low Cost property
  • Free breakfast available
~19.66 Miles from Santee
Fairfield Inn Orangeburg
+1-800-997-5148Check Rates
663 Citadel, Orangeburg, SC 29118
  • 3.5/5, Average Hotel Reviews
  • 3-star property
  • Free complimentary breakfast
~20.28 Miles from Santee
Comfort Inn & Suites - Orangeburg
+1-800-997-5149Check Rates
746 Citadel Rd., Orangeburg, SC 29118 Website
  • 4.0/5, Very Good Review Score
  • Low-priced Rural hotel
  • 14 suites in property
~20.37 Miles from Santee
Days Inn - Manning
+1-800-230-4134Check Rates
2825 Paxville Highway, Manning, SC 29102~20.47 Miles from Santee
Sleep Inn Orangeburg
+1-800-997-5148Check Rates
3689 Saint Matthews Rd., Orangeburg, SC 29118
  • 3.5/5, Average Read Reviews
  • Two-star Suburban hotel
  • Free breakfast available
~20.49 Miles from Santee

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