Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles from Lake Marion Resort and Marina and 18 miles from Edisto Memorial Gardens.

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Santee Hotels/Accommodations

Days Inn
+1-800-230-4134Check Rates
9074 Old Highway Six, Santee, SC 29142
  • Low priced property
Image of Holiday Inn SanteeHoliday Inn Santee
+1-800-997-5148Check Rates
139 Bradford Blvd., Santee, SC 29142
  • 3.0/5, Average Latest Reviews
  • 3 star Highway property
  • 84 sleeping rooms in hotel
Exterior of Comfort Inn & SuitesComfort Inn & Suites - Santee
+1-800-997-5149Check Rates
221 Britain St., Santee, SC 29142
  • 4.0/5, Very Good Latest Reviews
  • Two-star Lake property
  • Check-in: 3:00 PM
Image of Quality Inn & SuitesQuality Inn & Suites
+1-800-230-4134Check Rates
8929 Old Number Six Highway, Santee, SC 29142
Image of Howard Johnson SanteeHoward Johnson Santee in Santee
+1-800-997-5148Check Rates
249 Britain St., Santee, SC 29142
  • 3.0/5, Average Review Score
  • Two star Golf Course hotel
  • 60 rooms in hotel
Image of Whitten InnWhitten Inn
+1-800-997-5149Check Rates
123 Mall St., Santee, SC 29142
  • 2.5/5, Poor Latest Reviews
  • 2 star Highway property
  • Check-in time: 2:00 pm
Hampton Inn Santee I 95
+1-800-230-4134Check Rates
9060 Old #6 Highway, Santee, SC 29142
  • 4.5/5, Very Good Guest Reviews
  • Three Star Highway property
  • 7 suites in property
Best Western Plus Santee Inn - Santee
+1-800-997-5148Check Rates
9059 Old Number Six Highway, Santee, SC 29142
  • 3-star hotel
Rodeway Inn Santee
+1-800-997-5149Check Rates
9117 Old Number 6 Highway, Santee, SC 29142
  • 3.0/5, Average Read Reviews
  • Economical Highway hotel
  • Check in time: 02:00 PM
Travelodge - Santee
+1-800-230-4134Check Rates
9091 Old Highway 6, Santee, SC 29142
  • 3.0/5, Average Review Score
  • Economical Golf Course hotel
  • 40 rooms in property
Econo Lodge
+1-800-997-5148Check Rates
9112 Old Number 6 Hww., Santee, SC 29142
  • Inexpensive Highway hotel
Peachtree Inn
+1-800-997-5149Check Rates
111 Conners Dr., Saint George, SC 29477
  • 4.5/5, Very Good Hotel Reviews
  • 3 star Highway hotel
  • 39 rooms in property
~15.51 Miles from Santee
Sunset Inn Manning - Manning
+1-800-230-4134Check Rates
5932 Alex Highway, Manning, SC 29102
  • 1.5/5, Terrible Reviews
  • Economical hotel
~16.27 Miles from Santee
Hampton Inn
+1-800-997-5148Check Rates
2822 Paxville Highway, Manning, SC 29102
  • 4.5/5, Very Good Read Reviews
  • Affordable Highway property
  • 73 rooms in hotel
~19.30 Miles from Santee
Quality Inn : 3031 Paxville Highway
+1-800-997-5149Check Rates
3031 Paxville Highway, Manning, SC 29102~19.32 Miles from Santee
Country Inn & Suites - Orangeburg
+1-800-230-4134Check Rates
731 Citadel Rd., Orangeburg, SC 29118~19.66 Miles from Santee
Fairfield Inn Orangeburg - Orangeburg
+1-800-997-5148Check Rates
663 Citadel, Orangeburg, SC 29118
  • 3.0/5, Average Read Reviews
  • 3 star hotel
  • Check in time: 3:00 PM
~20.28 Miles from Santee
Comfort Inn & Suites in Orangeburg
+1-800-997-5149Check Rates
746 Citadel Rd., Orangeburg, SC 29118 Website
  • 4.0/5, Very Good Read Reviews
  • Cheap Rural property
  • 3 floors in property
~20.37 Miles from Santee
Days Inn
+1-800-230-4134Check Rates
2825 Paxville Highway, Manning, SC 29102~20.47 Miles from Santee
Exterior of Southern LodgeSouthern Lodge - Orangeburg
+1-800-997-5148Check Rates
3616 St. Matthews Rd., Orangeburg, SC 29118 Website
  • 2-star Highway hotel
  • Check-in: 2.00pm
~20.48 Miles from Santee

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