Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles from Lake Marion Resort and Marina and 18 miles from Edisto Memorial Gardens.

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Santee Hotels & Accommodations

Days Inn - Santee
+1-800-230-4134Check Rates
9074 Old Highway Six, Santee, SC 29142
  • Low Cost hotel
Image of Holiday Inn SanteeHoliday Inn Santee
+1-800-997-5148Check Rates
139 Bradford Blvd., Santee, SC 29142
  • 3.0/5, Average Review Score
  • 3-star Highway hotel
  • 84 rooms in property
Image of Comfort Inn & SuitesComfort Inn & Suites in Santee
+1-800-997-5149Check Rates
221 Britain St., Santee, SC 29142
  • 4.0/5, Very Good Reviews
  • Economy Lake property
  • Free complimentary breakfast
Photo of Quality Inn & SuitesQuality Inn & Suites
+1-800-230-4134Check Rates
8929 Old Number Six Highway, Santee, SC 29142
  • 3.0/5, Average Guest Reviews
  • Cheap Highway property
  • 2 meeting rooms in property
Image of Howard Johnson SanteeHoward Johnson Santee
+1-800-997-5148Check Rates
249 Britain St., Santee, SC 29142
  • 3.0/5, Average Latest Reviews
  • Low priced Golf Course property
  • Comp. Breakfast
Exterior of Whitten InnWhitten Inn - Santee
+1-800-997-5149Check Rates
123 Mall St., Santee, SC 29142
  • 2.5/5, Poor Hotel Reviews
  • Economy Highway property
  • 117 rooms in property
Hampton Inn Santee I 95 in Santee
+1-800-230-4134Check Rates
9060 Old #6 Highway, Santee, SC 29142
  • 4.5/5, Very Good Recent Reviews
  • Midscale Highway property
  • Free breakfast available
Photo of Econo Lodge SanteeEcono Lodge Santee in Santee
+1-800-997-5148Check Rates
9112 Old Number 6 Highway, Santee, SC 29142
  • 3.5/5, Average Recent Reviews
  • Low-priced Highway hotel
  • Check-in: 02:00 PM
Rodeway Inn Santee
+1-800-997-5149Check Rates
9117 Old Number 6 Highway, Santee, SC 29142
  • 3.0/5, Average Read Reviews
  • Low priced Highway hotel
  • Free breakfast available
Best Western Plus Santee Inn - Santee
+1-800-230-4134Check Rates
9059 Old Number Six Highway, Santee, SC 29142
  • Affordable property
Travelodge
+1-800-997-5148Check Rates
9091 Old Highway 6, Santee, SC 29142
  • 3.0/5, Average Reviews
  • Cheap Golf Course property
  • Check in time: 1.00
Peachtree Inn
+1-800-997-5149Check Rates
111 Conners Dr., Saint George, SC 29477
  • 4.5/5, Very Good Latest Reviews
  • 3-star Highway property
  • Free breakfast available
~15.51 Miles from Santee
Sunset Inn Manning in Manning
+1-800-230-4134Check Rates
5932 Alex Highway, Manning, SC 29102~16.27 Miles from Santee
Hampton Inn in Manning
+1-800-997-5148Check Rates
2822 Paxville Highway, Manning, SC 29102
  • 4.5/5, Very Good Read Reviews
  • Three Star Highway property
  • 3 floors in property
~19.30 Miles from Santee
Quality Inn : 3031 Paxville Highway
+1-800-997-5149Check Rates
3031 Paxville Highway, Manning, SC 29102~19.32 Miles from Santee
Country Inn & Suites : 731 Citadel Rd.
+1-800-230-4134Check Rates
731 Citadel Rd., Orangeburg, SC 29118
  • 3.5/5, Average Reviews
  • Low priced hotel
  • 81 rooms in hotel
~19.66 Miles from Santee
Fairfield Inn Orangeburg - Orangeburg
+1-800-997-5148Check Rates
663 Citadel, Orangeburg, SC 29118
  • 3.0/5, Average Reviews
  • 3 star property
  • Free breakfast available
~20.28 Miles from Santee
Comfort Inn & Suites
+1-800-997-5149Check Rates
746 Citadel Rd., Orangeburg, SC 29118 Website
  • 4.0/5, Very Good Read Reviews
  • Inexpensive Rural property
  • Free comp. breakfast
~20.37 Miles from Santee
Days Inn
+1-800-230-4134Check Rates
2825 Paxville Highway, Manning, SC 29102~20.47 Miles from Santee
Photo of Southern LodgeSouthern Lodge
+1-800-997-5148Check Rates
3616 St. Matthews Rd., Orangeburg, SC 29118 Website
  • Low priced Highway hotel
  • 43 sleeping rooms in hotel
~20.48 Miles from Santee

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