Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles from Lake Marion Resort and Marina and 18 miles from Edisto Memorial Gardens.

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Santee Hotels/Accommodations

Days Inn
+1-800-230-4134Check Rates
9074 Old Highway Six, Santee, SC 29142
  • Inexpensive hotel
Image of Holiday Inn SanteeHoliday Inn Santee - Santee
+1-800-997-5148Check Rates
139 Bradford Blvd., Santee, SC 29142
  • 3.0/5, Average Review Score
  • 3 star Highway property
  • Hotel has 4 floors
Exterior of Comfort Inn & SuitesComfort Inn & Suites
+1-800-997-5149Check Rates
221 Britain St., Santee, SC 29142
  • 3.5/5, Average Guest Reviews
  • Low Cost Lake hotel
  • 3 floors in property
Exterior of Quality Inn & SuitesQuality Inn & Suites in Santee
+1-800-230-4134Check Rates
8929 Old Number Six Highway, Santee, SC 29142
  • 3.0/5, Average Review Score
  • Economical Highway hotel
  • 153 rooms in property
Exterior of Howard Johnson SanteeHoward Johnson Santee : 249 Britain St.
+1-800-997-5148Check Rates
249 Britain St., Santee, SC 29142
  • 3.0/5, Average Reviews
  • Economy Golf Course property
  • Check in time: 03:00pm
Exterior of Whitten InnWhitten Inn
+1-800-997-5149Check Rates
123 Mall St., Santee, SC 29142
  • 2.5/5, Poor Read Reviews
  • Economy Highway hotel
  • 2 floors in hotel
Hampton Inn Santee I 95 - Santee
+1-800-230-4134Check Rates
9060 Old #6 Highway, Santee, SC 29142
  • 4.5/5, Very Good Reviews
  • Mid-scale Highway property
  • 3 floors in hotel
Image of Rodeway Inn SanteeRodeway Inn Santee
+1-800-997-5148Check Rates
9117 Old Number 6 Highway, Santee, SC 29142
  • 3.0/5, Average Latest Reviews
  • Cheap Highway hotel
  • Complimentary breakfast is offered
Best Western Plus Santee Inn
+1-800-997-5149Check Rates
9059 Old Number Six Highway, Santee, SC 29142
  • 3-star property
Travelodge : 9091 Old Highway 6
+1-800-230-4134Check Rates
9091 Old Highway 6, Santee, SC 29142
  • 2.5/5, Poor Read Reviews
  • Low-priced Golf Course hotel
  • Free breakfast
Econo Lodge
+1-800-997-5148Check Rates
9112 Old Number 6 Hww., Santee, SC 29142
  • Economy Highway hotel
  • 37 rooms in property
Peachtree Inn
+1-800-997-5149Check Rates
111 Conners Dr., Saint George, SC 29477
  • 4.5/5, Very Good Hotel Reviews
  • Three Star Highway property
  • Complimentary breakfast is offered
~15.51 Miles from Santee
Sunset Inn Manning - Manning
+1-800-230-4134Check Rates
5932 Alex Highway, Manning, SC 29102~16.27 Miles from Santee
Hampton Inn
+1-800-997-5148Check Rates
2822 Paxville Highway, Manning, SC 29102
  • 4.5/5, Very Good Reviews
  • Three Star Highway hotel
  • Hotel has 73 rooms
~19.30 Miles from Santee
Quality Inn - Manning
+1-800-997-5149Check Rates
3031 Paxville Highway, Manning, SC 29102~19.32 Miles from Santee
Country Inn & Suites : 731 Citadel Rd.
+1-800-230-4134Check Rates
731 Citadel Rd., Orangeburg, SC 29118
  • 3.5/5, Average Reviews
  • Low priced hotel
  • 4 floors in hotel
~19.66 Miles from Santee
Fairfield Inn Orangeburg in Orangeburg
+1-800-997-5148Check Rates
663 Citadel, Orangeburg, SC 29118~20.28 Miles from Santee
Comfort Inn & Suites : 746 Citadel Rd.
+1-800-997-5149Check Rates
746 Citadel Rd., Orangeburg, SC 29118 Website
  • 4.0/5, Very Good Hotel Reviews
  • Economical Rural property
  • Check-in: 3 pm
~20.37 Miles from Santee
Days Inn - Manning
+1-800-230-4134Check Rates
2825 Paxville Highway, Manning, SC 29102~20.47 Miles from Santee
Exterior of Southern LodgeSouthern Lodge
+1-800-997-5148Check Rates
3616 St. Matthews Rd., Orangeburg, SC 29118 Website
  • Cheap Highway property
  • 43 rooms in property
~20.48 Miles from Santee

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