Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles from Lake Marion Resort and Marina and 18 miles from Edisto Memorial Gardens.

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Santee Hotels & Accommodations

Days Inn in Santee
+1-800-230-4134Check Rates
9074 Old Highway Six, Santee, SC 29142
  • Inexpensive property
Image of Holiday Inn SanteeHoliday Inn Santee
+1-800-997-5148Check Rates
139 Bradford Blvd., Santee, SC 29142
  • 3.0/5, Average Reviews
  • Affordable Highway hotel
  • Check in: 4:00pm
Photo of Comfort Inn & SuitesComfort Inn & Suites in Santee
+1-800-997-5149Check Rates
221 Britain St., Santee, SC 29142
Exterior of Quality Inn & SuitesQuality Inn & Suites - Santee
+1-800-230-4134Check Rates
8929 Old Number Six Highway, Santee, SC 29142
  • 3.0/5, Average Hotel Reviews
  • Two star Highway hotel
  • 17 suites in property
Exterior of Howard Johnson SanteeHoward Johnson Santee
+1-800-997-5148Check Rates
249 Britain St., Santee, SC 29142
  • 3.5/5, Average Guest Reviews
  • 2-star Golf Course property
  • Hotel has 60 rooms
Photo of Whitten InnWhitten Inn in Santee
+1-800-997-5149Check Rates
123 Mall St., Santee, SC 29142
Hampton Inn Santee I 95 - Santee
+1-800-230-4134Check Rates
9060 Old #6 Highway, Santee, SC 29142
  • 4.5/5, Very Good Read Reviews
  • Mid-scale Highway hotel
  • 81 sleeping rooms in hotel
Best Western Plus Santee Inn in Santee
+1-800-997-5148Check Rates
9059 Old Number Six Highway, Santee, SC 29142
  • Midscale hotel
Econo Lodge Santee
+1-800-997-5149Check Rates
9112 Old Number 6 Highway, Santee, SC 29142
  • 3.5/5, Average Reviews
  • Economy Highway hotel
  • Free breakfast available
Rodeway Inn Santee
+1-800-230-4134Check Rates
9117 Old Number 6 Highway, Santee, SC 29142
  • 3.0/5, Average Recent Reviews
  • Low priced Highway hotel
  • Check in time: 02:00 PM
Travelodge in Santee
+1-800-997-5148Check Rates
9091 Old Highway 6, Santee, SC 29142
  • 3.0/5, Average Latest Reviews
  • 2 star Golf Course property
  • Free breakfast available
Peachtree Inn : 111 Conners Dr.
+1-800-997-5149Check Rates
111 Conners Dr., Saint George, SC 29477
  • 4.5/5, Very Good Guest Reviews
  • Three Star Highway property
  • Check-in: 3.00
~15.51 Miles from Santee
Sunset Inn Manning : 5932 Alex Highway
+1-800-230-4134Check Rates
5932 Alex Highway, Manning, SC 29102~16.27 Miles from Santee
Hampton Inn : 2822 Paxville Highway
+1-800-997-5148Check Rates
2822 Paxville Highway, Manning, SC 29102
  • 4.5/5, Very Good Read Reviews
  • Mid-scale Highway property
  • Gym is available on property
~19.30 Miles from Santee
Quality Inn : 3031 Paxville Highway
+1-800-997-5149Check Rates
3031 Paxville Highway, Manning, SC 29102~19.32 Miles from Santee
Country Inn & Suites : 731 Citadel Rd.
+1-800-230-4134Check Rates
731 Citadel Rd., Orangeburg, SC 29118~19.66 Miles from Santee
Fairfield Inn Orangeburg
+1-800-997-5148Check Rates
663 Citadel, Orangeburg, SC 29118~20.28 Miles from Santee
Comfort Inn & Suites : 746 Citadel Rd.
+1-800-997-5149Check Rates
746 Citadel Rd., Orangeburg, SC 29118 Website
  • 4.0/5, Very Good Hotel Reviews
  • Low priced Rural hotel
  • Check in: 3 pm
~20.37 Miles from Santee
Days Inn
+1-800-230-4134Check Rates
2825 Paxville Highway, Manning, SC 29102
  • 2.5/5, Poor Reviews
  • Economical hotel
~20.47 Miles from Santee
Sleep Inn Orangeburg - Orangeburg
+1-800-997-5148Check Rates
3689 Saint Matthews Rd., Orangeburg, SC 29118
  • 3.5/5, Average Guest Reviews
  • Economy Suburban hotel
  • Hotel has 69 rooms
~20.49 Miles from Santee

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