HOTELS in Santee (South Carolina)

Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles from Lake Marion Resort and Marina and 18 miles from Edisto Memorial Gardens.

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Santee Hotels, Motels & Accommodations

Days Inn - Santee
+1-800-230-4134Check Rates
9074 Old Highway Six, Santee, SC 29142
  • Low Cost property
Photo of Holiday Inn SanteeHoliday Inn Santee : 139 Bradford Blvd.
+1-800-997-5148Check Rates
139 Bradford Blvd., Santee, SC 29142
  • 3.0/5, Average Recent Reviews
  • Three Star Highway property
  • 84 sleeping rooms in hotel
Exterior of Comfort Inn & SuitesComfort Inn & Suites - Santee
+1-800-997-5149Check Rates
221 Britain St., Santee, SC 29142
Exterior of Quality Inn & SuitesQuality Inn & Suites
+1-800-230-4134Check Rates
8929 Old Number Six Highway, Santee, SC 29142
Photo of Howard Johnson SanteeHoward Johnson Santee - Santee
+1-800-997-5148Check Rates
249 Britain St., Santee, SC 29142
  • 3.5/5, Average Hotel Reviews
  • Low-priced Golf Course property
  • Check in: 03:00pm
Exterior of Whitten InnWhitten Inn - Santee
+1-800-997-5149Check Rates
123 Mall St., Santee, SC 29142
Hampton Inn Santee I 95
+1-800-230-4134Check Rates
9060 Old #6 Highway, Santee, SC 29142
  • 4.5/5, Very Good Review Score
  • Three Star Highway property
  • Comp. Breakfast
Image of Rodeway Inn SanteeRodeway Inn Santee in Santee
+1-800-997-5148Check Rates
9117 Old Number 6 Highway, Santee, SC 29142
  • 3.0/5, Average Read Reviews
  • Cheap Highway hotel
  • Comp. Breakfast
Econo Lodge Santee
+1-800-997-5149Check Rates
9112 Old Number 6 Highway, Santee, SC 29142
  • 3.5/5, Average Guest Reviews
  • Two star Highway hotel
  • Check-in: 02:00 PM
Best Western Plus Santee Inn : 9059 Old Number Six Highway
+1-800-230-4134Check Rates
9059 Old Number Six Highway, Santee, SC 29142
  • Midscale property
Travelodge : 9091 Old Highway 6
+1-800-997-5148Check Rates
9091 Old Highway 6, Santee, SC 29142
  • 3.0/5, Average Recent Reviews
  • Two-star Golf Course property
  • Free complimentary breakfast
Peachtree Inn - Saint George
+1-800-997-5149Check Rates
111 Conners Dr., Saint George, SC 29477
  • 4.5/5, Very Good Reviews
  • Three Star Highway property
  • Free breakfast
~15.51 Miles from Santee
Sunset Inn Manning - Manning
+1-800-230-4134Check Rates
5932 Alex Highway, Manning, SC 29102~16.27 Miles from Santee
Hampton Inn in Manning
+1-800-997-5148Check Rates
2822 Paxville Highway, Manning, SC 29102
  • 4.5/5, Very Good Recent Reviews
  • Mid-scale Highway hotel
  • 73 sleeping rooms in hotel
~19.30 Miles from Santee
Quality Inn
+1-800-997-5149Check Rates
3031 Paxville Highway, Manning, SC 29102~19.32 Miles from Santee
Country Inn & Suites : 731 Citadel Rd.
+1-800-230-4134Check Rates
731 Citadel Rd., Orangeburg, SC 29118
  • 3.5/5, Average Reviews
  • Cheap property
  • Hotel has 81 rooms
~19.66 Miles from Santee
Fairfield Inn Orangeburg
+1-800-997-5148Check Rates
663 Citadel, Orangeburg, SC 29118~20.28 Miles from Santee
Comfort Inn & Suites
+1-800-997-5149Check Rates
746 Citadel Rd., Orangeburg, SC 29118 Website
  • 4.0/5, Very Good Reviews
  • Economical Rural hotel
  • 3 floors in property
~20.37 Miles from Santee
Days Inn : 2825 Paxville Highway
+1-800-230-4134Check Rates
2825 Paxville Highway, Manning, SC 29102~20.47 Miles from Santee
Sleep Inn Orangeburg
+1-800-997-5148Check Rates
3689 Saint Matthews Rd., Orangeburg, SC 29118
  • 3.5/5, Average Review Score
  • Two star Suburban property
  • Check in time: 2:00 PM
~20.49 Miles from Santee

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