HOTELS in Santee (South Carolina)

Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles from Lake Marion Resort and Marina and 18 miles from Edisto Memorial Gardens.

Find my perfect hotel Rooms Check-In Check-Out  
Click to see Calendar Click to see Calendar Start My Search >
(select the discounts you qualify for)
Star Rating




Hotel Name

Price Range (USD)
to
Amenities







Set My Filter

Santee Hotels & Accommodations

Days Inn
+1-800-230-4134Check Rates
9074 Old Highway Six, Santee, SC 29142
  • 2 star property
Photo of Holiday Inn Santee Holiday Inn Santee : 139 Bradford Blvd.
+1-800-997-5148Check Rates
139 Bradford Blvd., Santee, SC 29142
  • 3.0/5, Average Guest Reviews
  • Three Star Highway property
  • Gym / Fitness Center Available
Image of Comfort Inn & Suites Comfort Inn & Suites in Santee
+1-800-997-5149Check Rates
221 Britain St., Santee, SC 29142
  • 4.0/5, Very Good Reviews
  • Economical Lake property
  • Fitness + Health Center
Exterior of Quality Inn & Suites Quality Inn & Suites - Santee
+1-800-230-4134Check Rates
8929 Old Number Six Highway, Santee, SC 29142
  • 3.0/5, Average Reviews
  • Low priced Highway hotel
  • 153 rooms in property
Image of Howard Johnson Santee Howard Johnson Santee in Santee
+1-800-997-5148Check Rates
249 Britain St., Santee, SC 29142
  • 3.5/5, Average Latest Reviews
  • 2 star Golf Course hotel
  • 2 floors in hotel
Photo of Whitten Inn Whitten Inn in Santee
+1-800-997-5149Check Rates
123 Mall St., Santee, SC 29142
  • 2.5/5, Poor Reviews
  • Two-star Highway property
  • 3 conference rooms in property
Hampton Inn Santee I 95 : 9060 Old #6 Highway
+1-800-230-4134Check Rates
9060 Old #6 Highway, Santee, SC 29142
  • 4.5/5, Very Good Review Score
  • Affordable Highway hotel
  • Hotel has 3 floors
Exterior of Rodeway Inn Santee Rodeway Inn Santee
+1-800-997-5148Check Rates
9117 Old Number 6 Highway, Santee, SC 29142
  • 3.0/5, Average Recent Reviews
  • Low Cost Highway property
  • Check in time: 02:00 PM
Econo Lodge Santee
+1-800-997-5149Check Rates
9112 Old Number 6 Highway, Santee, SC 29142
  • 3.5/5, Average Read Reviews
  • Cheap Highway hotel
  • Free complimentary breakfast
Best Western Plus Santee Inn - Santee
+1-800-230-4134Check Rates
9059 Old Number Six Highway, Santee, SC 29142
  • Affordable hotel
Travelodge
+1-800-997-5148Check Rates
9091 Old Highway 6, Santee, SC 29142
  • 3.0/5, Average Reviews
  • Two-star Golf Course property
  • Check in: 1.00
Peachtree Inn
+1-800-997-5149Check Rates
111 Conners Dr., Saint George, SC 29477
  • 4.5/5, Very Good Review Score
  • Affordable Highway hotel
  • Check in time: 3.00
~15.51 Miles from Santee
Sunset Inn Manning : 5932 Alex Highway
+1-800-230-4134Check Rates
5932 Alex Highway, Manning, SC 29102 ~16.27 Miles from Santee
Hampton Inn
+1-800-997-5148Check Rates
2822 Paxville Highway, Manning, SC 29102
  • 4.5/5, Very Good Read Reviews
  • Three Star Highway hotel
  • Hotel has 73 rooms
~19.30 Miles from Santee
Quality Inn
+1-800-997-5149Check Rates
3031 Paxville Highway, Manning, SC 29102 ~19.32 Miles from Santee
Country Inn & Suites - Orangeburg
+1-800-230-4134Check Rates
731 Citadel Rd., Orangeburg, SC 29118
  • 3.5/5, Average Reviews
  • Low Cost property
  • Free complimentary breakfast
~19.66 Miles from Santee
Fairfield Inn Orangeburg in Orangeburg
+1-800-997-5148Check Rates
663 Citadel, Orangeburg, SC 29118
  • 3.5/5, Average Reviews
  • 3 star property
  • Free breakfast available
~20.28 Miles from Santee
Comfort Inn & Suites : 746 Citadel Rd.
+1-800-997-5149Check Rates
746 Citadel Rd., Orangeburg, SC 29118 Website
  • 4.0/5, Very Good Hotel Reviews
  • Cheap Rural hotel
  • Gym / Fitness Center Available
~20.37 Miles from Santee
Days Inn
+1-800-230-4134Check Rates
2825 Paxville Highway, Manning, SC 29102 ~20.47 Miles from Santee
Sleep Inn Orangeburg in Orangeburg
+1-800-997-5148Check Rates
3689 Saint Matthews Rd., Orangeburg, SC 29118
  • 3.5/5, Average Review Score
  • Economy Suburban property
  • 4 floors in hotel
~20.49 Miles from Santee

 [1 - 20 of 50]   


Next: See My Santee Hotels with Pricing >




Back to TOP