Seneca South Carolina Hotels & Motels

Only hotels in Seneca are listed below. Search for cheap and discounted hotel and motel rates in or near Seneca, SC for your upcoming personal or group trip. We provide the best Seneca, South Carolina motel and hotel rooms. Browse the Seneca area hotels to find the perfect lodging! Please use the provided map of the Seneca hotels. Group booking? Search Seneca Group Hotel Discounts

The Seneca center point is about 6 miles from Memorial Stadium and 6 miles from Clemson Amtrak Station.

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Seneca Hotels, Motels & Accommodations

Image of Quality InnQuality Inn in Seneca
+1-800-230-4134Check Rates
226 Hi Tech Rd., Seneca, SC 29678
Image of Best Western Executive InnBest Western Executive Inn
+1-800-997-5148Check Rates
511 Us Highway 123 Bypass, Seneca, SC 29678
  • 3.5/5, Average Latest Reviews
  • Mid-scale Rural hotel
  • 3 floors in property
Days Inn
+1-800-997-5149Check Rates
11015 N.radio Station Rd., Seneca, SC 29678
Photo of Hampton InnHampton Inn
+1-800-230-4134Check Rates
851 Tiger Blvd., Clemson, SC 29631~5.99 Miles from Seneca
Courtyard by Marriott Clemson
+1-800-997-5148Check Rates
201 Canoy Lane, Clemson, SC 29631
  • 4.5/5, Very Good Reviews
  • 3 star property
  • 5 suites in property
~6.59 Miles from Seneca
Photo of Days InnDays Inn - Clemson
+1-800-997-5149Check Rates
1387 Tiger Blvd., Clemson, SC 29631~6.80 Miles from Seneca
Photo of Hotel Tillman Univ. AreaHotel Tillman Univ. Area : 1303 Tiger Blvd.
+1-800-230-4134Check Rates
1303 Tiger Blvd., Clemson, SC 29631
  • 4.5/5, Very Good Reviews
  • 2 star hotel
  • Free breakfast
~6.80 Miles from Seneca
Photo of Holiday Inn Express & SuitesHoliday Inn Express & Suites - Clemson
+1-800-997-5148Check Rates
1381 Tiger Blvd., Clemson, SC 29631~6.80 Miles from Seneca
University Inn & Conference Center
+1-800-997-5149Check Rates
1310 Tiger Blvd., Clemson, SC 29631
  • 2.0/5, Poor Hotel Reviews
  • Economical Downtown hotel
  • 4 floors in hotel
~7.08 Miles from Seneca
Exterior of Comfort Inn Clemson S.c. (Clemson University Area)Comfort Inn Clemson S.c. (Clemson University Area) in Clemson
+1-800-230-4134Check Rates
1305 Tiger Blvd., Clemson, SC 29631 Website
  • 4.0/5, Very Good Latest Reviews
  • Mid-scale Downtown property
  • Hotel has 4 floors
~7.12 Miles from Seneca
Microtel Inn & Suites in Anderson
+1-800-997-5148Check Rates
102 Electric City Blvd., Anderson, SC 29621
  • 4.0/5, Very Good Hotel Reviews
  • Economy Highway hotel
  • Complimentary breakfast is offered
~15.54 Miles from Seneca
Holiday Inn Express & Suites Anderson & Clemson in Anderson
+1-800-997-5149Check Rates
107 Interstate Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Reviews
  • 3 star Highway hotel
  • Check-in: 3:00PM
~15.58 Miles from Seneca
Country Inn & Suites - Anderson
+1-800-230-4134Check Rates
116 Interstate Blvd., Anderson, SC 29621
  • 5.0/5, Excellent Latest Reviews
  • 3 star Highway property
  • Hotel has 55 rooms
~15.61 Miles from Seneca
Baymont Inn & Suites
+1-800-997-5148Check Rates
128 Interstate Blvd., Anderson, SC 29621
  • 3.5/5, Average Guest Reviews
  • 3 star Highway hotel
  • 58 rooms in property
~15.65 Miles from Seneca
Comfort Suites : 118 Interstate Blvd.
+1-800-997-5149Check Rates
118 Interstate Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Guest Reviews
  • 2-star Highway property
  • Check-in: 3:00pm
~15.73 Miles from Seneca
Hampton Inn Anderson in Anderson
+1-800-230-4134Check Rates
120 Insterstate Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Reviews
  • Midscale Highway hotel
  • 3 floors in hotel
~15.84 Miles from Seneca
Hilton Garden Inn in Anderson
+1-800-997-5148Check Rates
115 Destination Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Latest Reviews
  • Mid-scale Highway property
  • 5 floors in property
~16.03 Miles from Seneca
Anderson Days Inn Clemson - Anderson
+1-800-997-5149Check Rates
1007 Smiths Mill Rd., Anderson, SC 29625
  • 3.5/5, Average Hotel Reviews
  • Low Cost Highway hotel
  • 2 floors in hotel
~16.04 Miles from Seneca
Holiday Inn Anderson - Anderson
+1-800-230-4134Check Rates
3509 Clemson Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Read Reviews
  • Mid-scale Downtown property
  • 115 rooms in hotel
~18.40 Miles from Seneca
Photo of Home Towne Suites AndersonHome Towne Suites Anderson : 151 Civic Center Blvd.
+1-800-997-5148Check Rates
151 Civic Center Blvd., Anderson, SC 29625 Website
  • 4.0/5, Very Good Read Reviews
  • Two-star Lake property
  • Hotel has 78 rooms
~18.44 Miles from Seneca

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