Seneca South Carolina Hotels & Motels

Only hotels in Seneca are listed below. Search for cheap and discounted hotel and motel rates in or near Seneca, SC for your upcoming personal or group trip. We provide the best Seneca, South Carolina motel and hotel rooms. Browse the Seneca area hotels to find the perfect lodging! Please use the provided map of the Seneca hotels. Group booking? Search Seneca Group Hotel Discounts

The Seneca center point is about 6 miles from Memorial Stadium and 6 miles from Clemson Amtrak Station.

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Seneca Hotels, Motels & Accommodations

Image of Quality InnQuality Inn
+1-800-230-4134Check Rates
226 Hi Tech Rd., Seneca, SC 29678
Image of Best Western Executive InnBest Western Executive Inn in Seneca
+1-800-997-5148Check Rates
511 Us Highway 123 Bypass, Seneca, SC 29678
  • 3.5/5, Average Hotel Reviews
  • Mid-scale Rural property
  • 58 sleeping rooms in hotel
Days Inn
+1-800-997-5149Check Rates
11015 N.radio Station Rd., Seneca, SC 29678
Photo of Hampton InnHampton Inn in Clemson
+1-800-230-4134Check Rates
851 Tiger Blvd., Clemson, SC 29631
  • 4.5/5, Very Good Read Reviews
  • Midscale property
  • Check in: 4:00 pm
~5.99 Miles from Seneca
Courtyard by Marriott Clemson in Clemson
+1-800-997-5148Check Rates
201 Canoy Lane, Clemson, SC 29631
  • 4.5/5, Very Good Read Reviews
  • Midscale hotel
  • Check in time: 3:00pm
~6.59 Miles from Seneca
Image of Days InnDays Inn
+1-800-997-5149Check Rates
1387 Tiger Blvd., Clemson, SC 29631~6.80 Miles from Seneca
Photo of Holiday Inn Express & SuitesHoliday Inn Express & Suites in Clemson
+1-800-230-4134Check Rates
1381 Tiger Blvd., Clemson, SC 29631
  • 4.5/5, Very Good Reviews
  • 3 star Downtown hotel
  • 93 sleeping rooms in hotel
~6.80 Miles from Seneca
Image of Hotel Tillman Univ. AreaHotel Tillman Univ. Area - Clemson
+1-800-997-5148Check Rates
1303 Tiger Blvd., Clemson, SC 29631~6.80 Miles from Seneca
University Inn & Conference Center
+1-800-997-5149Check Rates
1310 Tiger Blvd., Clemson, SC 29631
  • 2.0/5, Poor Recent Reviews
  • Cheap Downtown hotel
  • 8 meeting rooms in hotel
~7.08 Miles from Seneca
Exterior of Comfort Inn Clemson S.c. (Clemson University Area)Comfort Inn Clemson S.c. (Clemson University Area) - Clemson
+1-800-230-4134Check Rates
1305 Tiger Blvd., Clemson, SC 29631 Website
  • 4.0/5, Very Good Latest Reviews
  • Three Star Downtown property
  • Free comp. breakfast
~7.12 Miles from Seneca
Microtel Inn & Suites - Anderson
+1-800-997-5148Check Rates
102 Electric City Blvd., Anderson, SC 29621
  • 4.0/5, Very Good Recent Reviews
  • Low Cost Highway property
  • Comp. Breakfast
~15.54 Miles from Seneca
Holiday Inn Express & Suites Anderson & Clemson
+1-800-997-5149Check Rates
107 Interstate Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Review Score
  • Mid-scale Highway hotel
  • 75 rooms in hotel
~15.58 Miles from Seneca
Country Inn & Suites
+1-800-230-4134Check Rates
116 Interstate Blvd., Anderson, SC 29621
  • 5.0/5, Excellent Latest Reviews
  • Midscale Highway property
  • Hotel has 17 suites
~15.61 Miles from Seneca
Baymont Inn & Suites
+1-800-997-5148Check Rates
128 Interstate Blvd., Anderson, SC 29621
  • 3.5/5, Average Latest Reviews
  • Mid-scale Highway property
  • Hotel has 2 floors
~15.65 Miles from Seneca
Comfort Suites
+1-800-997-5149Check Rates
118 Interstate Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Review Score
  • Low Cost Highway hotel
  • Check-in: 3:00pm
~15.73 Miles from Seneca
Hampton Inn Anderson - Anderson
+1-800-230-4134Check Rates
120 Insterstate Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Reviews
  • 3 star Highway hotel
  • 72 sleeping rooms in hotel
~15.84 Miles from Seneca
Hilton Garden Inn - Anderson
+1-800-997-5148Check Rates
115 Destination Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Guest Reviews
  • Affordable Highway hotel
  • Hotel has 10 meeting rooms
~16.03 Miles from Seneca
Anderson Days Inn Clemson in Anderson
+1-800-997-5149Check Rates
1007 Smiths Mill Rd., Anderson, SC 29625
  • 3.5/5, Average Review Score
  • 2 star Highway property
  • Check-in time: 3:00p
~16.04 Miles from Seneca
Holiday Inn Anderson : 3509 Clemson Blvd.
+1-800-230-4134Check Rates
3509 Clemson Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Review Score
  • 3 star Downtown property
  • 2 meeting rooms in property
~18.40 Miles from Seneca
Home Towne Suites Anderson in Anderson
+1-800-997-5148Check Rates
151 Civic Center Blvd., Anderson, SC 29625
  • 4.5/5, Very Good Guest Reviews
  • Economical Lake hotel
  • Check-in time: 3:00pm
~18.44 Miles from Seneca

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