Seneca South Carolina Hotels & Motels

Only hotels in Seneca are listed below. Search for cheap and discounted hotel and motel rates in or near Seneca, SC for your upcoming personal or group trip. We provide the best Seneca, South Carolina motel and hotel rooms. Browse the Seneca area hotels to find the perfect lodging! Please use the provided map of the Seneca hotels. Group booking? Search Seneca Group Hotel Discounts

The Seneca center point is about 6 miles from Memorial Stadium and 6 miles from Clemson Amtrak Station.

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Seneca Hotels/Motels & Accommodations

Image of Quality InnQuality Inn
+1-800-230-4134Check Rates
226 Hi Tech Rd., Seneca, SC 29678
  • 3.5/5, Average Latest Reviews
  • Mid-scale hotel
  • Gym / Fitness Center Available
Exterior of Best Western Executive InnBest Western Executive Inn
+1-800-997-5148Check Rates
511 Us Highway 123 Bypass, Seneca, SC 29678
  • 3.5/5, Average Review Score
  • 3-star Rural hotel
  • Check-in time: 14:00
Days Inn : 11015 N.radio Station Rd.
+1-800-997-5149Check Rates
11015 N.radio Station Rd., Seneca, SC 29678
Photo of Hampton InnHampton Inn
+1-800-230-4134Check Rates
851 Tiger Blvd., Clemson, SC 29631~5.99 Miles from Seneca
Courtyard by Marriott Clemson : 201 Canoy Lane
+1-800-997-5148Check Rates
201 Canoy Lane, Clemson, SC 29631
  • 4.5/5, Very Good Recent Reviews
  • Three Star property
  • 2 meeting rooms in property
~6.59 Miles from Seneca
Photo of Days InnDays Inn : 1387 Tiger Blvd.
+1-800-997-5149Check Rates
1387 Tiger Blvd., Clemson, SC 29631~6.80 Miles from Seneca
Image of Hotel Tillman Univ. AreaHotel Tillman Univ. Area
+1-800-230-4134Check Rates
1303 Tiger Blvd., Clemson, SC 29631~6.80 Miles from Seneca
Image of Holiday Inn Express & SuitesHoliday Inn Express & Suites
+1-800-997-5148Check Rates
1381 Tiger Blvd., Clemson, SC 29631
  • 4.5/5, Very Good Hotel Reviews
  • 3-star Downtown hotel
  • Check in: 03:00
~6.80 Miles from Seneca
University Inn & Conference Center - Clemson
+1-800-997-5149Check Rates
1310 Tiger Blvd., Clemson, SC 29631
  • 2.0/5, Poor Hotel Reviews
  • Two star Downtown property
  • Check in: 3 pm
~7.08 Miles from Seneca
Image of Comfort Inn Clemson S.c. (Clemson University Area)Comfort Inn Clemson S.c. (Clemson University Area)
+1-800-230-4134Check Rates
1305 Tiger Blvd., Clemson, SC 29631 Website
  • 4.0/5, Very Good Reviews
  • Affordable Downtown property
  • 18 suites in hotel
~7.12 Miles from Seneca
Microtel Inn & Suites
+1-800-997-5148Check Rates
102 Electric City Blvd., Anderson, SC 29621
  • 4.0/5, Very Good Review Score
  • Low priced Highway property
  • Gym / Fitness Center Available
~15.54 Miles from Seneca
Holiday Inn Express & Suites Anderson & Clemson : 107 Interstate Blvd.
+1-800-997-5149Check Rates
107 Interstate Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Reviews
  • 3-star Highway property
  • Hotel has 75 rooms
~15.58 Miles from Seneca
Country Inn & Suites : 116 Interstate Blvd.
+1-800-230-4134Check Rates
116 Interstate Blvd., Anderson, SC 29621
  • 5.0/5, Excellent Read Reviews
  • Midscale Highway hotel
  • 5 floors in property
~15.61 Miles from Seneca
Baymont Inn & Suites in Anderson
+1-800-997-5148Check Rates
128 Interstate Blvd., Anderson, SC 29621
  • 3.5/5, Average Read Reviews
  • Midscale Highway hotel
  • Check in: 03:00pm
~15.65 Miles from Seneca
Comfort Suites
+1-800-997-5149Check Rates
118 Interstate Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Latest Reviews
  • Two-star Highway hotel
  • Hotel has 4 floors
~15.73 Miles from Seneca
Hampton Inn Anderson in Anderson
+1-800-230-4134Check Rates
120 Insterstate Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Guest Reviews
  • 3 star Highway hotel
  • 3 floors in property
~15.84 Miles from Seneca
Hilton Garden Inn
+1-800-997-5148Check Rates
115 Destination Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Latest Reviews
  • Mid-scale Highway hotel
  • 10 meeting rooms in property
~16.03 Miles from Seneca
Anderson Days Inn Clemson
+1-800-997-5149Check Rates
1007 Smiths Mill Rd., Anderson, SC 29625
  • 3.5/5, Average Reviews
  • Cheap Highway property
  • Free breakfast available
~16.04 Miles from Seneca
Holiday Inn Anderson in Anderson
+1-800-230-4134Check Rates
3509 Clemson Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Latest Reviews
  • Mid-scale Downtown hotel
  • Check-in: 3:00 PM
~18.40 Miles from Seneca
Home Towne Suites Anderson
+1-800-997-5148Check Rates
151 Civic Center Blvd., Anderson, SC 29625
  • 4.5/5, Very Good Guest Reviews
  • Economical Lake hotel
  • 78 sleeping rooms in hotel
~18.44 Miles from Seneca

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