Seneca South Carolina Hotels & Motels

Only hotels in Seneca are listed below. Search for cheap and discounted hotel and motel rates in or near Seneca, SC for your upcoming personal or group trip. We provide the best Seneca, South Carolina motel and hotel rooms. Browse the Seneca area hotels to find the perfect lodging! Please use the provided map of the Seneca hotels. Group booking? Search Seneca Group Hotel Discounts

The Seneca center point is about 6 miles from Memorial Stadium and 6 miles from Clemson Amtrak Station.

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Seneca Hotels/Motels & Accommodations

Exterior of Quality Inn Quality Inn
+1-800-230-4134Check Rates
226 Hi Tech Rd., Seneca, SC 29678
  • 3.5/5, Average Guest Reviews
  • 3-star property
  • Check-in time: 03:00PM
Exterior of Best Western Executive Inn Best Western Executive Inn
+1-800-997-5148Check Rates
511 Us Highway 123 Bypass, Seneca, SC 29678
  • 3.5/5, Average Reviews
  • 3-star Rural property
  • Hotel has 3 floors
Days Inn
+1-800-997-5149Check Rates
11015 N.radio Station Rd., Seneca, SC 29678
Photo of Hampton Inn Hampton Inn in Clemson
+1-800-230-4134Check Rates
851 Tiger Blvd., Clemson, SC 29631
  • 4.5/5, Very Good Latest Reviews
  • Three Star property
  • Check-in: 4:00 pm
~5.99 Miles from Seneca
Courtyard by Marriott Clemson - Clemson
+1-800-997-5148Check Rates
201 Canoy Lane, Clemson, SC 29631
  • 4.5/5, Very Good Reviews
  • 3-star property
  • 110 rooms in property
~6.59 Miles from Seneca
Image of Days Inn Days Inn in Clemson
+1-800-997-5149Check Rates
1387 Tiger Blvd., Clemson, SC 29631
  • 3.5/5, Average Guest Reviews
  • Economical hotel
  • 2 floors in hotel
~6.80 Miles from Seneca
Photo of Hotel Tillman Univ. Area Hotel Tillman Univ. Area - Clemson
+1-800-230-4134Check Rates
1303 Tiger Blvd., Clemson, SC 29631
  • 4.5/5, Very Good Review Score
  • 2-star property
  • Check-in: 3.00PM
~6.80 Miles from Seneca
Image of Holiday Inn Express & Suites Holiday Inn Express & Suites
+1-800-997-5148Check Rates
1381 Tiger Blvd., Clemson, SC 29631
  • 4.5/5, Very Good Recent Reviews
  • Affordable Downtown hotel
  • Fitness center on property
~6.80 Miles from Seneca
University Inn & Conference Center : 1310 Tiger Blvd.
+1-800-997-5149Check Rates
1310 Tiger Blvd., Clemson, SC 29631
  • 2.0/5, Poor Recent Reviews
  • Inexpensive Downtown hotel
  • Gym / Fitness Center Available
~7.08 Miles from Seneca
Photo of Comfort Inn Clemson S.c. (Clemson University Area) Comfort Inn Clemson S.c. (Clemson University Area)
+1-800-230-4134Check Rates
1305 Tiger Blvd., Clemson, SC 29631 Website
  • 4.0/5, Very Good Read Reviews
  • 3 star Downtown hotel
  • Hotel has 18 suites
~7.12 Miles from Seneca
Microtel Inn & Suites : 102 Electric City Blvd.
+1-800-997-5148Check Rates
102 Electric City Blvd., Anderson, SC 29621
  • 4.0/5, Very Good Latest Reviews
  • Low-priced Highway hotel
  • Complimentary breakfast is offered
~15.54 Miles from Seneca
Holiday Inn Express & Suites Anderson & Clemson
+1-800-997-5149Check Rates
107 Interstate Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Recent Reviews
  • Midscale Highway property
  • Free complimentary breakfast
~15.58 Miles from Seneca
Country Inn & Suites
+1-800-230-4134Check Rates
116 Interstate Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Read Reviews
  • Midscale Highway hotel
  • 5 floors in property
~15.61 Miles from Seneca
Baymont Inn & Suites in Anderson
+1-800-997-5148Check Rates
128 Interstate Blvd., Anderson, SC 29621
  • 3.5/5, Average Reviews
  • 3-star Highway property
  • Complimentary breakfast is offered
~15.65 Miles from Seneca
Comfort Suites in Anderson
+1-800-997-5149Check Rates
118 Interstate Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Review Score
  • Low-priced Highway property
  • Check-in time: 3:00pm
~15.73 Miles from Seneca
Hampton Inn Anderson in Anderson
+1-800-230-4134Check Rates
120 Insterstate Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Review Score
  • Affordable Highway property
  • 3 floors in hotel
~15.84 Miles from Seneca
Hilton Garden Inn - Anderson
+1-800-997-5148Check Rates
115 Destination Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Hotel Reviews
  • 3-star Highway property
  • 10 meeting rooms in hotel
~16.03 Miles from Seneca
Anderson Days Inn Clemson
+1-800-997-5149Check Rates
1007 Smiths Mill Rd., Anderson, SC 29625
  • 3.5/5, Average Hotel Reviews
  • Economy Highway property
  • Free comp. breakfast
~16.04 Miles from Seneca
Holiday Inn Anderson - Anderson
+1-800-230-4134Check Rates
3509 Clemson Blvd., Anderson, SC 29621
  • 4.5/5, Very Good Read Reviews
  • 3 star Downtown property
  • Gym is available on property
~18.40 Miles from Seneca
Photo of Home Towne Suites Anderson Home Towne Suites Anderson
+1-800-997-5148Check Rates
151 Civic Center Blvd., Anderson, SC 29625 Website
  • 4.0/5, Very Good Reviews
  • Economical Lake property
  • 78 sleeping rooms in hotel
~18.44 Miles from Seneca

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