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49221 Hotels/Accommodations

Super 8 : 1091 West Us 223
+1-888-389-4121
1091 West Us 223, Adrian, MI 49221
  • Economy Downtown property
From$39
Average 3.0 /5 Guest Reviews Call BookMore Details
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Travelodge by Wyndham Adrian - Adrian
+1-888-675-2083
1575 West Maumee St., Adrian, MI 49221
  • 2-star Suburban property
  • Check-in: 2 pm
From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Carlton Lodge Adrian in Adrian
+1-800-716-8490
1629 West Maumee St., Adrian, MI 49221
  • Affordable Rural hotel
  • Hotel has 14 suites
From$64
Average 3.5 /5 Guest Reviews Call BookMore Details
Comfort Inn & Suites
+1-800-805-5223
425 Industrial Dr., Adrian, MI 49221
  • 3-star hotel
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Amp Suites Adrian
+1-888-965-1860
1335 South Main St., Adrian, MI 49221
  • Affordable hotel
  • Check-in: 15:00
From$90
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Adrian - Adrian
+1-888-788-5576
1091 Us Highway 223, Adrian, MI 49221
  • Low Cost Downtown hotel
  • Free breakfast available
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Adrian, an IHG Hotel : 1077 East Us Highway 223
+1-888-897-9207
1077 East Us Highway 223, Adrian, MI 49221
  • 3-star Rural property
  • 60 rooms in property
From$129
Very Good 4.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Brooklyn in Brooklyn
+1-888-311-4278
419 South Main / M50, Brooklyn, MI 49230 ~16.07 miles northwest of 49221
  • Economical hotel
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites
+1-888-469-4795
401 Powell Dr., Dundee, MI 48131 ~20.18 miles east of 49221
  • 3-star Rural hotel
  • Fitness / Gym is on-site
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Country Inn & Suites by Radisson, Dundee, MI
+1-888-734-9421
665 Tecumseh, Dundee, MI 48131 ~20.24 miles east of 49221
  • Three Star Rural hotel
  • 69 rooms in property
From$81
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Dundee in Dundee
+1-888-841-5292
102 Whitetail Dr., Dundee, MI 48131 ~20.34 miles east of 49221
  • 3 star Highway property
  • Hotel has 40 suites
From$82
Very Good 4.0 /5 Reviews Call BookMore Details
Quality Inn : 111 Waterstradt Commerce Dr.
+1-888-455-5160
111 Waterstradt Commerce Dr., Dundee, MI 48131 ~20.35 miles east of 49221
  • Low priced Rural hotel
  • 58 rooms in hotel
From$49
Average 3.0 /5 Reviews Call BookMore Details
American Inn and Suites Dundee
+1-888-965-8297
130 Outer Dr., Dundee, MI 48131 ~20.52 miles east of 49221
  • Mid-scale Highway hotel
  • 61 sleeping rooms in hotel
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Wauseon : 8319 Oh 108
+1-888-906-6358
8319 Oh 108, Wauseon, OH 43567 ~22.24 miles south of 49221
  • Low Cost Rural hotel
  • Check-in time: 3:00 pm
From$48
Average 3.5 /5 Latest Reviews Call BookMore Details
M Star Hotel Wauseon : 8225 State Rd. 108
+1-888-749-6785
8225 State Rd. 108, Wauseon, OH 43567 ~22.29 miles south of 49221
  • Affordable hotel
  • 35 sleeping rooms in hotel
From$90
Poor 2.0 /5 Reviews Call BookMore Details
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Rodeway Inn
+1-888-878-9982
8224 State Route 108, Wauseon, OH 43567 ~22.30 miles south of 49221
  • Two-star Highway property
  • Check-in: 1:30Pm
From$45
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Wauseon, an IHG Hotel
+1-888-389-4485
8135 State Route 108, Wauseon, OH 43567 ~22.41 miles south of 49221
  • Affordable property
  • 15 suites in property
From$100
Average 3.0 /5 Reviews Call BookMore Details
Wingate by Wyndham Sylvania / Toledo
+1-888-389-4121
5480 South Main St., Sylvania, OH 43560 ~22.94 miles southeast of 49221
  • Affordable Suburban hotel
  • Access to gym on-site
From$88
Very Good 4.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Milan - Milan
+1-888-675-2083
1230 Dexter St., Milan, MI 48160 ~23.81 miles northeast of 49221
  • Cheap Suburban hotel
  • 63 rooms in property
From$55
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Saline
+1-800-716-8490
1250 East Michigan Ave., Saline, MI 48176 ~24.20 miles northeast of 49221
  • Three Star Highway property
  • 3 floors in property
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Baymont Swanton / Toledoairport in Swanrton
+1-800-805-5223
10753 Airport Highway, Swanrton, OH 43558 ~25.44 miles southeast of 49221
  • Low priced property
  • Check in time: 11:00 AM
From$59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn Chelsea in Chelsea
+1-888-965-1860
1645 Commerce Park Dr., Chelsea, MI 48118 ~27.06 miles north of 49221
  • Mid-scale Highway property
  • 3 floors in hotel
From$83
Average 3.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Chelsea - Chelsea
+1-888-788-5576
1540 Commerce Park Dr., Chelsea, MI 48118 ~27.14 miles north of 49221
  • Midscale Highway property
  • 3 floors in property
From$69
Average 3.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn Toledo - University
+1-888-897-9207
3530 Executive Pkwy., Toledo, OH 43606 ~27.50 miles southeast of 49221
  • Inexpensive Downtown property
  • 117 sleeping rooms in hotel
From$46
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn Toledo in Toledo
+1-888-311-4278
3560 Secor Rd., Toledo, OH 43606 ~27.58 miles southeast of 49221
  • Economy property
  • Complimentary breakfast is offered
Residence Inn Toledo Marriott - Toledo
+1-888-469-4795
3554 Secor Rd., Toledo, OH 43606 ~27.59 miles southeast of 49221
  • 3 star hotel
  • 110 suites in hotel
From$90
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard Toledo West - Toledo
+1-888-734-9421
3536 Secor Rd., Toledo, OH 43606 ~27.59 miles southeast of 49221
  • Affordable Suburban property
  • 118 sleeping rooms in hotel
From$99
Average 3.0 /5 Review Score Call BookMore Details
Econo Lodge Airport - Holland
+1-888-841-5292
1201 East Mall Dr., Holland, OH 43528 ~27.61 miles southeast of 49221
  • Economy Suburban hotel
  • Complimentary breakfast is offered
Holiday Inn Express & Suites Toledo West, an IHG Hotel - Toledo
+1-888-455-5160
3440 Secor Rd., Toledo, OH 43606 ~27.65 miles southeast of 49221
  • Three Star Suburban hotel
  • Hotel has an eco-friendly policy Read more
From$109
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Toledo/Westgate : 3434 Secor Rd.
+1-888-965-8297
3434 Secor Rd., Toledo, OH 43606 ~27.68 miles southeast of 49221
  • Affordable Suburban hotel
  • 111 rooms in property
From$119
Very Good 4.0 /5 Reviews Call BookMore Details
Red Roof Inn Toledo - Holland - Holland
+1-888-906-6358
1214 Corporate Dr., Holland, OH 43528 ~27.80 miles southeast of 49221
  • Two-star Suburban property
  • 2 floors in property
Quality Inn Toledo Airport
+1-888-749-6785
1401 East Mall Dr., Holland, OH 43528 ~27.87 miles southeast of 49221
  • Two-star Airport property
  • Free complimentary breakfast
From$49
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 Ann Arbor - Ann Arbor
+1-888-878-9982
3764 South State St., Ann Arbor, MI 48108 ~27.88 miles northeast of 49221
  • Two star hotel
  • Check-in: 15:00
From$46
Average 3.0 /5 Latest Reviews Call BookMore Details
Toledo Holland Courtyard Marriott
+1-888-389-4485
1435 East Mall Dr., Holland, OH 43528 ~27.90 miles southeast of 49221
  • Mid-scale Suburban hotel
  • Hotel has 149 rooms
From$89
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Staybridge Suites Ann Arbor- Univ of Michigan, an IHG Hotel
+1-888-389-4121
3850 Research Park Dr., Ann Arbor, MI 48108 ~27.90 miles northeast of 49221
  • Three Star Highway property
  • Fitness / Gym is on-site
From$119
Very Good 4.0 /5 Reviews Call BookMore Details
Towneplace Suites by Marriott Ann Arbor in Ann Arbor
+1-888-675-2083
1301 Briarwood Circle Dr., Ann Arbor, MI 48108 ~27.95 miles northeast of 49221
  • Economical Golf Course hotel
  • Free breakfast
From$150
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Exp Stes University Sou
+1-800-716-8490
3853 Research Park Dr., Ann Arbor, MI 48108 ~27.99 miles northeast of 49221
  • Affordable property
  • 94 rooms in hotel
From$90
Very Good 4.0 /5 Review Score Call BookMore Details
Hilton Garden Inn Ann Arbor
+1-800-805-5223
1401 Briarwood Circle, Ann Arbor, MI 48108 ~28.00 miles northeast of 49221
  • Midscale Highway hotel
  • Check-in: 3:00pm
From$119
Very Good 4.0 /5 Read Reviews Call BookMore Details
Sonesta Simply Suites Detroit Ann Arbor in Ann Arbor
+1-888-965-1860
701 Waymarket Way, Ann Arbor, MI 48103 ~28.03 miles northeast of 49221
  • Midscale Suburban hotel
  • Check in: 3:00 PM
From$66
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Extended Stay America Suites Toledo Holland
+1-888-788-5576
6155 Trust Dr., Holland, OH 43528 ~28.06 miles southeast of 49221
  • 3 star Suburban property
  • 3 floors in hotel
From$53
Average 3.0 /5 Read Reviews Call BookMore Details
Hawthorn Suites by Wyndham Holland/Toledo Area : 6101 Trust Dr.
+1-888-897-9207
6101 Trust Dr., Holland, OH 43528 ~28.10 miles southeast of 49221
  • Affordable Airport hotel
  • Fitness / Gym is on-site
From$45
Very Good 4.0 /5 Review Score Call BookMore Details
Even Hotels Ann Arbor, an IHG Hotel : 600 Briarwood Circle
+1-888-311-4278
600 Briarwood Circle, Ann Arbor, MI 48108 ~28.14 miles northeast of 49221
  • Affordable Suburban property
  • 6 meeting rooms in property
From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Knights Inn Maumee
+1-888-469-4795
1520 South Holland Sylvania Rd., Maumee, OH 43537 ~28.26 miles southeast of 49221
  • Mid-scale Highway hotel
  • Complimentary breakfast is offered
From$32
Average 3.0 /5 Review Score Call BookMore Details
The Kensington Hotel
+1-888-734-9421
3500 South State St., Ann Arbor, MI 48108 ~28.27 miles northeast of 49221
  • Three Star Suburban property
  • 10 meeting rooms in property
From$104
Very Good 4.0 /5 Read Reviews Call BookMore Details
Knights Inn Maumee : 1520s Holland Sylvania Rd.
+1-888-841-5292
1520s Holland Sylvania Rd., Maumee, OH 43537 ~28.27 miles southeast of 49221
  • Inexpensive Highway property
  • Check-in time: 14:00am
From$42
Average 3.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Ann Arbor - University of Michigan South in Ann Arbor
+1-888-455-5160
3505 South State St., Ann Arbor, MI 48108 ~28.33 miles northeast of 49221
  • Low Cost Downtown hotel
  • Free complimentary breakfast
From$29
Average 3.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites University South
+1-888-965-8297
3501 South State, Ann Arbor, MI 48108 ~28.33 miles northeast of 49221
  • 2-star Suburban hotel
  • 16 suites in property
From$67
Average 3.0 /5 Latest Reviews Call BookMore Details
Sonesta Es Suites Ann Arbor
+1-888-906-6358
800 Victors Way, Ann Arbor, MI 48108 ~28.37 miles northeast of 49221
  • 3 star Highway hotel
  • 2 floors in property
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hyatt Place Ann Arbor : 3223 South State St.
+1-888-749-6785
3223 South State St., Ann Arbor, MI 48108 ~28.42 miles northeast of 49221
  • Midscale Downtown hotel
  • Fitness center on property
From$99
Average 3.0 /5 Guest Reviews Call BookMore Details
Sheraton Ann Arbor Hotel - Ann Arbor
+1-888-878-9982
3200 Boardwalk, Ann Arbor, MI 48108 ~28.43 miles northeast of 49221
  • Mid-scale Suburban property
  • 6 floors in hotel
From$109
Very Good 4.0 /5 Latest Reviews Call BookMore Details

Next: Show All Available 49221 Hotels with Pricing

Graph: Next 20 Days of Adrian Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Adrian, MI discounts available. The chart reflects the cheapest Adrian hotel for each day and each star rating category.

FAQs about hotels near 49221

What are the most favored hotels near 49221?

Travelodge by Wyndham Adrian, Holiday Inn Express Adrian, an IHG Hotel and Hampton Inn & Suites are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 49221?

Carlton Lodge Adrian, Comfort Inn & Suites and Hampton Inn & Amp Suites Adrian are the top 3 luxury hotels near 49221.

What hotels are closest to the area of 49221?

Super 8, Travelodge by Wyndham Adrian, and Carlton Lodge Adrian are the properties closest to 49221.

How much does a cheap hotel near 49221 cost per night?

In the last year, a 2 star hotel near 49221 can be as cheap as $54.93 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 49221 cost per night?

In the last year, the average 3 star hotel near 49221 has been $112.99 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 49221?

Dundee, Even Hotels Ann Arbor, an IHG Hotel and The Kensington Hotel are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 49221?

Residence Inn Toledo Marriott, Toledo Holland Courtyard Marriott and Towneplace Suites by Marriott Ann Arbor are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 49221?

Quality Inn, Rodeway Inn and Comfort Inn Chelsea are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 49221?

Holiday Inn Express Adrian, an IHG Hotel, Holiday Inn Express & Suites Toledo West, an IHG Hotel and Staybridge Suites Ann Arbor- Univ of Michigan, an IHG Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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