Star Rating
Hotel Name
Price Range (USD) to
Amenities
+ More

78543 Hotels, Motels & Accommodations

Motel 6 Weslaco, TX - Weslaco
+1-888-389-4121
1024 West Expressway 83, Weslaco, TX 78596 ~8.75 miles south of 78543
  • Economy property
  • 3 floors in property
From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 78543" Get Alexa Skill →
Super 8 by Wyndham Weslaco
+1-888-675-2083
1702 East Expressway 83, Weslaco, TX 78596 ~8.95 miles south of 78543
  • Cheap Highway hotel
  • Free complimentary breakfast
From$35
Average 3.5 /5 Hotel Reviews Call BookMore Details
Victoria Palms Inn & Suites in Donna
+1-800-716-8490
602 North Victoria Rd., Donna, TX 78537 ~8.95 miles south of 78543
  • Mid-scale Resort hotel
  • 120 rooms in hotel
From$44
Very Good 4.0 /5 Review Score Call BookMore Details
Hampton Inn Weslaco
+1-800-805-5223
1004 Fairfield Blvd., Weslaco, TX 78596 ~9.01 miles south of 78543
  • Mid-scale property
  • Fitness center on property
From$90
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Best Western Town Center Inn
+1-888-965-1860
1005 Fairfield Blvd., Weslaco, TX 78596 ~9.04 miles south of 78543
  • Mid-scale Highway hotel
  • 62 sleeping rooms in hotel
From$52
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Express Inn : 3021 East Expressway 83
+1-888-788-5576
3021 East Expressway 83, Weslaco, TX 78596 ~9.36 miles south of 78543
  • Low-priced property
  • Free complimentary breakfast
From$60
Average 3.0 /5 Reviews Call BookMore Details
Comfort Inn & Suites Donna near I-2
+1-888-897-9207
495 West Expressway 83, Donna, TX 78537 ~9.49 miles southwest of 78543
  • Inexpensive Highway property
  • Hotel has 55 rooms
From$65
Very Good 4.0 /5 Reviews Call BookMore Details
La Copa Inn - Alamo
+1-888-311-4278
714 North Tower Rd., Alamo, TX 78516 ~9.64 miles southwest of 78543
  • Economical hotel
  • Check in time: 2:00
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Palm Aire Hotel and Suites in Weslaco
+1-888-469-4795
415 South International Blvd., Weslaco, TX 78596 ~9.80 miles south of 78543
  • Midscale Resort property
  • 193 rooms in property
From$45
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Weslaco, an IHG Hotel
+1-888-734-9421
421 South International Blvd., Weslaco, TX 78596 ~9.86 miles south of 78543
  • Affordable Suburban hotel
  • Free complimentary breakfast
From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Weslaco Inn
+1-888-841-5292
2716 East Business 83, Weslaco, TX 78596 ~10.03 miles south of 78543
  • Low Cost Highway property
  • Hotel has 2 floors
From$40
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Texas Inn and Suites City Center at University Dr.
+1-888-455-5160
202 North Highway 281 Exit University Dr., Edinburg, TX 78541 ~10.11 miles west of 78543
  • Low-priced Downtown hotel
  • 2 floors in hotel
From$34
Average 3.5 /5 Review Score Call BookMore Details
Texas Inn : 1210 East Canton Rd.
+1-888-965-8297
1210 East Canton Rd., Edinburg, TX 78539 ~10.72 miles west of 78543
  • Low priced Downtown hotel
  • Fitness + Health Center
From$38
Average 3.0 /5 Guest Reviews Call BookMore Details
Texas Inn and Suites City Center at University Dr. - Edinburg
+1-888-906-6358
202 North 25th Ave., Edinburg, TX 78539 ~11.11 miles west of 78543
  • Cheap hotel
From$35
Poor 2.0 /5 Reviews Call BookMore Details
Quality Inn & Suites at The Outlets Mercedes/Weslaco
+1-888-749-6785
4701 East Expressway 83, Mercedes, TX 78570 ~11.17 miles southeast of 78543
  • Mid-scale hotel
  • Check-in time: 3:00 pm
From$52
Very Good 4.0 /5 Read Reviews Call BookMore Details
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 78543" Get Alexa Skill →
La Quinta Inn & Suites by Wyndham Alamo Mcallen East in Alamo
+1-888-878-9982
909 East Frontage Rd., Alamo, TX 78516 ~11.32 miles southwest of 78543
  • Mid-scale Highway hotel
  • Hotel has 61 rooms
From$69
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Edinburg Tx : 1806 Closner Blvd.
+1-888-389-4485
1806 Closner Blvd., Edinburg, TX 78539 ~11.35 miles west of 78543
  • Inexpensive hotel
  • 49 rooms in property
From$44
Average 3.0 /5 Guest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Mercedes
+1-888-389-4121
7007 East Expressway 83, Mercedes, TX 78570 ~11.49 miles southeast of 78543
  • Midscale Highway property
  • Fitness center on property
From$69
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Best Western Plus Edinburg Inn & Suites in Edinburg
+1-888-675-2083
2708 South Us Highway 281 (Closner Blvd), Edinburg, TX 78539 ~11.64 miles west of 78543
  • 3-star Suburban hotel
  • Hotel has 2 floors
From$52
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Comfort Inn Edinburg South
+1-800-716-8490
4001 Closner, Edinburg, TX 78539 ~11.98 miles west of 78543
  • 3-star Highway hotel
  • Hotel has 55 rooms
From$60
Very Good 4.5 /5 Guest Reviews Call BookMore Details
TRU by Hilton Edinburg
+1-800-805-5223
407 West Trenton Rd., Edinburg, TX 78539 ~11.99 miles west of 78543
  • Three Star property
  • Access to gym on-site
From$90
Average 3.0 /5 Guest Reviews Call BookMore Details
Mainstay Suites Edinburg
+1-888-965-1860
4001 South Us Highway 281, Edinburg, TX 78539 ~11.99 miles west of 78543
  • Low priced Highway hotel
  • 3 floors in hotel
From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Edinburg-McAllen Area, an IHG Hotel : 3801 South Business Highway 281
+1-888-788-5576
3801 South Business Highway 281, Edinburg, TX 78539 ~12.09 miles west of 78543
  • 3 star Downtown property
  • 2 conference rooms in property
From$77
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Home2 Suites by Hilton Edinburg
+1-888-897-9207
411 West Trenton, Edinburg, TX 78539 ~12.17 miles west of 78543
  • Three Star property
  • Hotel has 14 rooms
From$90
Very Good 4.0 /5 Review Score Call BookMore Details
Towneplace Suites by Marriott Mcallen Edinburg
+1-888-311-4278
502 West Trenton Rd., Edinburg, TX 78539 ~12.29 miles west of 78543
  • Mid-scale Suburban hotel
  • Hotel has 95 rooms
From$79
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Rodeway Inn - San Juan
+1-888-469-4795
112 West Expressway 83, San Juan, TX 78589 ~12.64 miles southwest of 78543
  • 2 star hotel
  • 82 rooms in property
From$38
Average 3.0 /5 Recent Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Pharr RGV Medical Center : 4603 North Cage
+1-888-734-9421
4603 North Cage, Pharr, TX 78577 ~12.73 miles west of 78543
  • Midscale Highway hotel
  • Check in time: 03:00pm
From$65
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Pharr, TX : 4701 North Cage
+1-888-841-5292
4701 North Cage, Pharr, TX 78577 ~12.77 miles west of 78543
  • 2-star property
  • 110 rooms in hotel
From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Pharr North Mcallen : 4607 North Cage Blvd.
+1-888-455-5160
4607 North Cage Blvd., Pharr, TX 78577 ~12.85 miles west of 78543
  • 3-star Highway hotel
  • Hotel has 13 suites
From$62
Very Good 4.0 /5 Review Score Call BookMore Details
Red Roof Inn Pharr - McAllen
+1-888-965-8297
4401 North Cage Blvd., Pharr, TX 78577 ~12.94 miles west of 78543
  • Two star hotel
  • 2 floors in property
From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Pharr : 300 West Nolana Loop
+1-888-906-6358
300 West Nolana Loop, Pharr, TX 78577 ~12.99 miles west of 78543
  • Affordable Rural hotel
  • 96 sleeping rooms in hotel
From$67
Very Good 4.0 /5 Review Score Call BookMore Details
Texas Inn & Suites in Pharr
+1-888-749-6785
1130 East Expressway 83, Pharr, TX 78577 ~13.20 miles southwest of 78543
  • Economy Highway property
  • 2 floors in hotel
From$46
Average 3.5 /5 Read Reviews Call BookMore Details
Comfort Inn & Suites - Pharr
+1-888-878-9982
2706 North Cage Blvd., Pharr, TX 78577 ~13.43 miles west of 78543
  • Cheap Airport property
  • Complimentary breakfast is offered
From$58
Very Good 4.0 /5 Read Reviews Call BookMore Details
Woodspring Suites Pharr - Pharr
+1-888-389-4485
1207 West Expressway 83, Pharr, TX 78577 ~14.71 miles west of 78543
  • Economy Suburban hotel
  • Hotel has 4 floors
From$35
Very Good 4.0 /5 Reviews Call BookMore Details
Americas Best Value Inn Pharr - Pharr
+1-888-389-4121
1301 West Expressway 83, Pharr, TX 78577 ~15.09 miles west of 78543
  • Inexpensive Airport hotel
  • 58 rooms in property
From$47
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Pharr, an IHG Hotel in Pharr
+1-888-675-2083
205 West Nolana Loop, Pharr, TX 78577 ~15.21 miles southwest of 78543
  • Affordable Highway property
  • 88 rooms in hotel
From$80
Very Good 4.0 /5 Read Reviews Call BookMore Details
Texas Inn Downtown Mcallen in Mcallen
+1-800-716-8490
1420 East Jackson Ave., Mcallen, TX 78503 ~15.76 miles west of 78543
  • Three Star Downtown hotel
  • Free breakfast available
From$40
Average 3.0 /5 Latest Reviews Call BookMore Details
Motel 6 McAllen, TX - East
+1-800-805-5223
801 East Expressway 83, Mcallen, TX 78501 ~16.12 miles west of 78543
  • Two-star property
  • 99 rooms in property
From$60
Average 3.5 /5 Recent Reviews Call BookMore Details
Best Western McAllen Medical Center - Mcallen
+1-888-965-1860
300 East Expressway 83, Mcallen, TX 78503 ~16.55 miles west of 78543
  • 3 star hotel
  • Hotel has 92 rooms
From$62
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Mcallen : 10 West Expressway 83
+1-888-788-5576
10 West Expressway 83, Mcallen, TX 78503 ~16.69 miles west of 78543
  • 3 star Airport property
  • 5 floors in property
From$58
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Residence Inn by Marriott Mcallen
+1-888-897-9207
220 West Expressway 83 (I 2), Mcallen, TX 78501 ~16.84 miles west of 78543
  • Midscale Airport property
  • 3 floors in property
From$69
Very Good 4.0 /5 Read Reviews Call BookMore Details
Pear Tree Inn Mcallen in Mcallen
+1-888-311-4278
Pear Tree Inn Mcallen, Mcallen, TX 78501 ~16.89 miles west of 78543
  • Three Star Suburban property
  • Complimentary breakfast is offered
From$54
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Casa De Palmas Trademark Collection by Wyndham in Mcallen
+1-888-469-4795
101 North Main St., Mcallen, TX 78501 ~16.90 miles west of 78543
  • 3 star Downtown property
  • 165 sleeping rooms in hotel
From$79
Average 3.0 /5 Hotel Reviews Call BookMore Details
Drury Inn & Suites Mcallen in Mcallen
+1-888-734-9421
300 West Expressway 83, Mcallen, TX 78501 ~16.90 miles west of 78543
  • Mid-scale Convention Center property
  • Free breakfast
From$94
Very Good 4.5 /5 Recent Reviews Call BookMore Details
DoubleTree Suites by Hilton Hotel McAllen : 1800 South 2nd St.
+1-888-841-5292
1800 South 2nd St., Mcallen, TX 78503 ~16.95 miles west of 78543
  • High-end Downtown hotel
  • Hotel has 5 meeting rooms
From$84
Very Good 4.0 /5 Latest Reviews Call BookMore Details
La Copa Inn McAllen in Mcallen
+1-888-455-5160
1010 West Houston Ave., Mcallen, TX 78501 ~17.00 miles west of 78543
  • 2-star hotel
  • Check-in: 3:00 PM
From$37
Poor 2.0 /5 Reviews Call BookMore Details
Holiday Inn Mcallen – Medical Center Area : 612 West Expressway 83
+1-888-965-8297
612 West Expressway 83, Mcallen, TX 78501 ~17.01 miles west of 78543
  • Mid-scale Suburban property
  • Comp. Breakfast
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Baymont Inn & Suites by Wyndham
+1-888-906-6358
620 West Expressway 83 Hotel Baymont Inn, Mcallen, TX 78501 ~17.03 miles west of 78543
  • 3 star Highway hotel
  • Check-in time: 3:00 P.M
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Mcallen
+1-888-749-6785
620 West Expy 83, Mcallen, TX 78501 ~17.03 miles west of 78543
  • Affordable Highway hotel
  • Free complimentary breakfast
OYO Hotel McAllen Airport South
+1-888-878-9982
1301 South 9th St., Mcallen, TX 78501 ~17.04 miles west of 78543
  • Mid-scale Airport property
  • Check-in: 3:00 pm

Next: Show All Available 78543 Hotels with Pricing

Graph of Weslaco, TX Hotel Prices for Next 20 Days

Rates shown are nightly rates before taxes and do not necessarily reflect all Weslaco, TX discounts available. The chart reflects the cheapest Weslaco hotel for each day and each star rating category.

FAQs about hotels near 78543

What are the best rated hotels near 78543?

Comfort Inn Edinburg South, Drury Inn & Suites Mcallen and Motel 6 Weslaco, TX are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels near 78543?

DoubleTree Suites by Hilton Hotel McAllen, Victoria Palms Inn & Suites and Hampton Inn Weslaco are the top 3 luxury hotels near 78543.

What hotels are closest to the area of 78543?

Motel 6 Weslaco, TX, Super 8 by Wyndham Weslaco, and Victoria Palms Inn & Suites are the properties closest to 78543.

How much does a cheap hotel near 78543 cost per night?

In the last year, a 2 star hotel near 78543 can be as cheap as $56.76 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 78543 cost per night?

In the last year, the average 3 star hotel near 78543 has been $88.68 per night. (based on HotelPlanner prices)

How much does a luxury hotel near 78543 cost?

In the last year, the average 4 star hotel near 78543 has been $134.50 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 78543?

Victoria Palms Inn & Suites, Palm Aire Hotel and Suites and Weslaco Inn are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 78543?

Towneplace Suites by Marriott Mcallen Edinburg, Residence Inn by Marriott Mcallen and Casa De Palmas Trademark Collection by Wyndham are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 78543?

Comfort Inn Edinburg South, Comfort Inn & Suites Donna near I-2 and Quality Inn & Suites at The Outlets Mercedes are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular Best Western hotels near 78543?

Best Western Town Center Inn, Best Western Plus Edinburg Inn & Suites and Best Western McAllen Medical Center are the best rated Best Western branded hotels (based on user reviews score).

What are the best IHG hotels near 78543?

Holiday Inn Express Hotel & Suites Weslaco, an IHG Hotel, Holiday Inn Express & Suites Edinburg-McAllen Area, an IHG Hotel and Holiday Inn Express Hotel & Suites Pharr, an IHG Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Back to Top