Hotels in 29506 - Florence SC

Only hotels in 29506 zip code are listed below. Search for cheap and discount hotel rates in Florence, SC for your upcoming leisure or conference / group travel. We list the best 29506 hotels and motels so you can review the Florence hotel list below to find the perfect lodging. Hotels in Florence county and area code 843 are also listed.


Find availability nearby Rooms Check-In Check-Out  
Show Calendar Show Calendar Start My Search >
(select the discounts you qualify for)
Star Rating




Hotel Name

Price Range (USD)
to
Amenities







Set My Filter

29506 Hotels/Accommodations

Exterior of Holiday Inn Express Hotel & SuitesHoliday Inn Express Hotel & Suites in Florence
+1-800-230-4134Check Rates
2101 Florence Harllee Blvd., Florence, SC 29506
  • 4.0/5, Very Good Guest Reviews
  • 3-star Suburban property
  • Check-in time: 4:00 PM
Exterior of Comfort InnComfort Inn
+1-800-997-5148Check Rates
2693 East Highway 76, Marion, SC 29574
  • 2.5/5, Poor Reviews
  • 3 star Highway hotel
  • Check-in: 3:00 PM
~1.00 Miles from 29506
Hotel Florence An Ascend Hotel Collection Member in Florence
+1-800-997-5149Check Rates
136 West Evans St., Florence, SC 29501
  • 5.0/5, Excellent Guest Reviews
  • 3 star Downtown hotel
  • Check-in: 4:00pm
~2.39 Miles from 29506
Photo of America's Best Value Inn FlorenceAmerica's Best Value Inn Florence
+1-800-230-4134Check Rates
3024 Tv Rd., Florence, SC 29501~3.54 Miles from 29506
Exterior of Travel InnTravel Inn - Florence
+1-800-997-5148Check Rates
1811 West Lucas St., Florence, SC 29501
  • Inexpensive Highway hotel
  • Gym / Fitness Center Available
~4.04 Miles from 29506
Exterior of RamadaRamada : 1819 West Lucas St.
+1-800-997-5149Check Rates
1819 West Lucas St., Florence, SC 29501
  • 3.0/5, Average Read Reviews
  • Low Cost Highway property
  • Hotel has 190 rooms
~4.04 Miles from 29506
Photo of Best Western FlorenceBest Western Florence : 1808 West Lucas St.
+1-800-230-4134Check Rates
1808 West Lucas St., Florence, SC 29501
  • 3.5/5, Average Latest Reviews
  • Three Star Downtown property
  • 2 floors in property
~4.06 Miles from 29506
Super 8
+1-800-997-5148Check Rates
I 95 Exit 164 Behind Citgo, Florence, SC 29501
  • 3.5/5, Average Hotel Reviews
  • Cheap Highway property
  • 2 floors in hotel
~4.09 Miles from 29506
Comfort Inn
+1-800-997-5149Check Rates
1916 West Lucas St., Florence, SC 29501
  • 3.5/5, Average Hotel Reviews
  • Midscale Highway property
  • Hotel has 2 floors
~4.19 Miles from 29506
Baymont Inn & Suites Florence
+1-800-230-4134Check Rates
1826 West Lucas St., Florence, SC 29501
  • 4.0/5, Very Good Review Score
  • Economy Highway property
  • Check-in time: 3:00pm
~4.22 Miles from 29506
Econo Lodge : 1920 West Lucas St.
+1-800-997-5148Check Rates
1920 West Lucas St., Florence, SC 29501
  • 3.5/5, Average Latest Reviews
  • Low Cost Highway property
  • Check-in time: 2:.00PM
~4.26 Miles from 29506
Exterior of Suburban Extended Stay HotelSuburban Extended Stay Hotel : 1914 West Lucas St.
+1-800-997-5149Check Rates
1914 West Lucas St., Florence, SC 29501~4.43 Miles from 29506
Country Inn & Suites : 1739 Mandeville Rd.
+1-800-230-4134Check Rates
1739 Mandeville Rd., Florence, SC 29501
  • 4.0/5, Very Good Recent Reviews
  • Mid-scale Highway property
  • Check in: 3:00 pm
~4.51 Miles from 29506
Howard Johnson in Florence
+1-800-997-5148Check Rates
2038 West Lucas St., Florence, SC 29501
  • 2.5/5, Poor Review Score
  • 2 star Highway property
  • Hotel has 170 rooms
~4.52 Miles from 29506
Days Inn Florence : 2111 West Lucas St. / I 95
+1-800-997-5149Check Rates
2111 West Lucas St. / I 95, Florence, SC 29501~4.58 Miles from 29506
Image of Comfort SuitesComfort Suites : 2120 West Lucas St.
+1-800-230-4134Check Rates
2120 West Lucas St., Florence, SC 29501
  • 4.5/5, Very Good Read Reviews
  • 3 star Highway property
  • 77 rooms in hotel
~4.58 Miles from 29506
La Quinta Inn & Suites
+1-800-997-5148Check Rates
2123 West Lucas St., Florence, SC 29501
  • 3.5/5, Average Recent Reviews
  • Mid-scale Highway hotel
  • 4 suites in property
~4.58 Miles from 29506
Hampton Inn & Suites
+1-800-997-5149Check Rates
1735 Stokes Rd., Florence, SC 29501
  • 4.5/5, Very Good Hotel Reviews
  • Cheap Convention Center property
  • Gym is available on property
~4.61 Miles from 29506
Sleep Inn : 1833 Florence Park Dr.
+1-800-230-4134Check Rates
1833 Florence Park Dr., Florence, SC 29501
  • 3.5/5, Average Hotel Reviews
  • Two star Highway property
  • Check in time: 3:00pm
~4.72 Miles from 29506
Microtel Inn & Suites by Wyndham Florence
+1-800-997-5148Check Rates
1912 Enterprise Dr., Florence, SC 29502
  • 2 star Highway property
  • Check-in: 1:00pm
~4.79 Miles from 29506
Red Roof Inn in Florence
+1-800-997-5149Check Rates
2690 David Mcleod Blvd., Florence, SC 29501
  • 3.5/5, Average Latest Reviews
  • Low-priced Highway property
  • 112 rooms in hotel
~5.99 Miles from 29506
Fairfield Inn by Marriott in Florence
+1-800-230-4134Check Rates
140 Dunbarton Dr., Florence, SC 29501
  • 3.0/5, Average Guest Reviews
  • Midscale Convention Center hotel
  • Check in: 3:00pm
~6.02 Miles from 29506
Quality Inn & Suites
+1-800-997-5148Check Rates
150 Dunbarton Dr., Florence, SC 29501
  • 4.0/5, Very Good Review Score
  • 2-star Highway hotel
  • Gym / Fitness Center Available
~6.04 Miles from 29506
Hilton Garden Inn - Florence
+1-800-997-5149Check Rates
2671 Hospitality Blvd., Florence, SC 29501
  • 4.5/5, Very Good Read Reviews
  • Midscale Highway property
  • 186 rooms in property
~6.27 Miles from 29506
Residence Inn Florence Sc
+1-800-230-4134Check Rates
2660 Hospitality Blvd., Florence, SC 29501
  • 4.5/5, Very Good Guest Reviews
  • Affordable Suburban property
  • Free comp. breakfast
~6.30 Miles from 29506
Hampton Ste Florence Civic Center - Florence
+1-800-997-5148Check Rates
3000 Radio Dr., Florence, SC 29501
  • 4.5/5, Very Good Latest Reviews
  • Inexpensive Convention Center property
  • Hotel has 18 suites
~6.31 Miles from 29506
Springhill Suites Marriott in Florence
+1-800-997-5149Check Rates
2670 Hospitality Blvd., Florence, SC 29501
  • 4.5/5, Very Good Read Reviews
  • Mid-scale Convention Center hotel
  • Hotel has 4 floors
~6.32 Miles from 29506
Florence Courtyard by Marriott in Florence
+1-800-230-4134Check Rates
2680 Hospitality Blvd., Florence, SC 29501
  • 4.5/5, Very Good Hotel Reviews
  • Three Star Convention Center property
  • 3 floors in hotel
~6.33 Miles from 29506
Home2 Suites by Hilton
+1-800-997-5148Check Rates
900 Woody Jones Blvd., Florence, SC 29501
  • Midscale Convention Center property
  • Hotel has an eco-friendly policy See policy
~6.62 Miles from 29506
Holiday Inn Express & Suites Florence Civic Center
+1-800-997-5149Check Rates
3440 West Radio Dr., Florence, SC 29501
  • 4.5/5, Very Good Latest Reviews
  • 3-star Convention Center property
  • Check in: 3:00 PM
~6.74 Miles from 29506
Travelodge Florence - Florence
+1-800-230-4134Check Rates
3783a West Palmetto St., Florence, SC 29502
  • 2.5/5, Poor Read Reviews
  • 2-star Highway property
  • Check-in time: 2pm
~8.78 Miles from 29506
Florence Inn & Suites
+1-800-997-5148Check Rates
3821 Bancroft Rd., Florence, SC 29501
  • Cheap Highway property
  • Check in: 14.00
~8.90 Miles from 29506
Treetop Inn
+1-800-997-5149Check Rates
3932 West Palmetto St., Florence, SC 29501
  • Economy Highway property
  • 2 floors in hotel
~9.19 Miles from 29506
Ramada Inn Florence Sc : 3311 Meadors Rd.
+1-800-230-4134Check Rates
3311 Meadors Rd., Florence, SC 29501
  • 3.0/5, Average Hotel Reviews
  • Two star Highway hotel
  • 120 rooms in property
~9.35 Miles from 29506
Best Western Executive Inn - Latta
+1-800-997-5148Check Rates
1534 Highway 38 West, Latta, SC 29565
  • 4.5/5, Very Good Recent Reviews
  • 3-star Highway property
  • Check-in time: 3:00 PM
~14.71 Miles from 29506
Budget Inn
+1-800-997-5149Check Rates
2200 Cale Yarborough Highway, Timmonsville, SC 29161
  • Inexpensive hotel
  • Hotel has 2 floors
~16.09 Miles from 29506
Landmark Inn : 1301 South 4th St.
+1-800-230-4134Check Rates
1301 South 4th St., Hartsville, SC 29550
  • Mid-scale Rural property
  • Check in: 3:00pm
~21.39 Miles from 29506
Quality Inn - Hartsville
+1-800-997-5148Check Rates
903 South 5th St., Hartsville, SC 29550
  • 4.0/5, Very Good Hotel Reviews
  • Low-priced Downtown hotel
  • Hotel has 2 floors
~21.96 Miles from 29506
Fairfield Inn Hartsville in Hartsville
+1-800-997-5149Check Rates
200 South 4th St., Hartsville, SC 29550~22.56 Miles from 29506
The Inn at the Crossroads
+1-800-230-4134Check Rates
128 West Main St., Lake City, SC 29560
  • Mid-scale Downtown property
  • 3 floors in hotel
~23.27 Miles from 29506
Days Inn
+1-800-997-5148Check Rates
170 South Ron Mcnair Blvd., Lake City, SC 29560
  • 3.5/5, Average Review Score
  • Economical Downtown property
  • 30 rooms in property
~23.35 Miles from 29506
Quality Inn
+1-800-997-5149Check Rates
817 Radford Blvd., Dillon, SC 29536
  • 3.5/5, Average Reviews
  • Inexpensive property
~25.77 Miles from 29506
Days Inn Dillon : 823 Radford Blvd.
+1-800-230-4134Check Rates
823 Radford Blvd., Dillon, SC 29536
  • 2.5/5, Poor Read Reviews
  • Two star Suburban property
  • Check in time: 03:00 PM
~25.79 Miles from 29506
Red Roof Inn
+1-800-997-5148Check Rates
810 Radford Blvd., Dillon, SC 29536
  • 3.0/5, Average Reviews
  • Economy hotel
~25.81 Miles from 29506
Super 8 in Dillon
+1-800-997-5149Check Rates
1203 Radford Blvd., Dillon, SC 29536~25.90 Miles from 29506
Imperial Motel
+1-800-230-4134Check Rates
1306 N.main St., Mullins, SC 29574
  • Economy Rural hotel
  • Check-in time: 2:00pm
~26.78 Miles from 29506
Americas Best Value Inn in Bishopville
+1-800-997-5148Check Rates
27 Charlenes Lane, Bishopville, SC 29010
  • 3.5/5, Average Latest Reviews
  • Economical Highway hotel
  • Free complimentary breakfast
~27.83 Miles from 29506
Quality Inn in Bennettsville
+1-800-997-5149Check Rates
213 Us Highway 15 / 401 Bypass East, Bennettsville, SC 29512
  • 5.0/5, Excellent Latest Reviews
  • Two-star Highway property
  • 50 rooms in property
~29.01 Miles from 29506
Days Inn
+1-800-230-4134Check Rates
820 Market St., Cheraw, SC 29520~34.60 Miles from 29506
Quality Inn - Cheraw
+1-800-997-5148Check Rates
885 Chesterfield Highway, Cheraw, SC 29520
  • 2 star Golf Course property
  • Hotel has 2 floors
~35.47 Miles from 29506



Next: Show All Available 29506 Hotels with Pricing >