Hotels in 46221 - Indianapolis IN

Only hotels in 46221 zip code are listed below. Search for cheap and discount hotel rates in Indianapolis, IN for your upcoming leisure or conference / group travel. We list the best 46221 hotels and motels so you can review the Indianapolis hotel list below to find the perfect lodging. Hotels in Marion county and area code 317 are also listed.


Find availability nearby Rooms Check-In Check-Out  
Show Calendar Show Calendar Start My Search >
(select the discounts you qualify for)
Star Rating




Hotel Name

Price Range (USD)
to
Amenities







Set My Filter

46221 Hotels/Accommodations

Photo of Country Inn & Suites Indianapolis Airport SouthCountry Inn & Suites Indianapolis Airport South - Indianapolis
+1-800-230-4134Check Rates
5630 Flight School Dr., Indianapolis, IN 46221
  • 4.5/5, Very Good Hotel Reviews
  • 3 star Airport property
  • Hotel has 2 meeting rooms
Photo of Quality Inn & Suites AirportQuality Inn & Suites Airport
+1-800-997-5148Check Rates
2631 South Lynhurst Dr., Indianapolis, IN 46241
  • 2.5/5, Poor Reviews
  • 2 star Airport hotel
  • 4 floors in property
~2.64 Miles from 46221
Exterior of Comfort Suites IndianapolisComfort Suites Indianapolis : 2750 Fortune Circle West
+1-800-997-5149Check Rates
2750 Fortune Circle West, Indianapolis, IN 46241
  • 4.0/5, Very Good Guest Reviews
  • Midscale Airport hotel
  • 70 rooms in property
~2.70 Miles from 46221
La Quinta Inn Indianapolis Airport #534
+1-800-230-4134Check Rates
5316 West Southern Ave., Indianapolis, IN 46241
  • 3.5/5, Average Hotel Reviews
  • Economy Airport property
  • Check-in: 2:00pm
~2.72 Miles from 46221
Exterior of Fairfield Inn by Marriott Indianapolis AirportFairfield Inn by Marriott Indianapolis Airport
+1-800-997-5148Check Rates
5220 West Southern Ave., Indianapolis, IN 46241
  • Low-priced Airport property
  • Gym is available on property
~2.72 Miles from 46221
Photo of Hilton Garden Inn Indianapolis AirportHilton Garden Inn Indianapolis Airport
+1-800-997-5149Check Rates
8910 Hatfield Dr., Indianapolis, IN 46241
  • Affordable Airport hotel
  • 5 floors in hotel
~2.75 Miles from 46221
Image of Jameson Inn IndianapolisJameson Inn Indianapolis - Indianapolis
+1-800-230-4134Check Rates
5860 Fortune Circle West, Indianapolis, IN 46241
  • 2.0/5, Poor Read Reviews
  • Cheap Airport hotel
  • Free complimentary breakfast
~2.75 Miles from 46221
Exterior of Indianapolis Airport RamadaIndianapolis Airport Ramada - Indianapolis
+1-800-997-5148Check Rates
5601 Fortune Circle West, Indianapolis, IN 46241
  • 3.5/5, Average Reviews
  • 3 star Airport hotel
  • Airport shuttle provided
~2.77 Miles from 46221
Residence Inn by Marriott Indianapolis Airport
+1-800-997-5149Check Rates
5224 West Southern Ave., Indianapolis, IN 46241
  • 3-star Airport property
  • Hotel has 95 rooms
~2.77 Miles from 46221
La Quinta Inn Executive Drive - Indianapolis
+1-800-230-4134Check Rates
2650 Executive Dr., Indianapolis, IN 46241
  • 4.0/5, Very Good Latest Reviews
  • 2-star Airport property
  • Shuttle to airport available
~2.80 Miles from 46221
Knights Inn Indianapolis Airport South
+1-800-997-5148Check Rates
4909 Knights Way, Indianapolis, IN 46217
  • 2.0/5, Poor Recent Reviews
  • 2-star Highway hotel
  • Airport shuttle available
~2.82 Miles from 46221
Extended Stay America Deluxe Version Airport : 5350 West Southern Ave.
+1-800-997-5149Check Rates
5350 West Southern Ave., Indianapolis, IN 46241
  • 3.5/5, Average Recent Reviews
  • Mid-scale Beach property
  • Hotel has 121 rooms
~2.84 Miles from 46221
Quality Inn Downtown South
+1-800-230-4134Check Rates
4502 South Harding St., Indianapolis, IN 46217
  • 3.5/5, Average Hotel Reviews
  • Low Cost Downtown hotel
  • Hotel has 65 rooms
~2.85 Miles from 46221
Econo Lodge Indianapolis Airport - Indianapolis
+1-800-997-5148Check Rates
5241 West Bradbury, Indianapolis, IN 46241~2.93 Miles from 46221
Hyatt Place Indianapolis Airport - Indianapolis
+1-800-997-5149Check Rates
5500 West Bradbury Ave., Indianapolis, IN 46241
  • 4.0/5, Very Good Read Reviews
  • 3-star Airport property
  • 3 meeting rooms in property
~2.98 Miles from 46221
Candlewood Suites Indianapolis Airport - Indianapolis
+1-800-230-4134Check Rates
5250 West Bradbury Ave., Indianapolis, IN 46241
  • 4.0/5, Very Good Read Reviews
  • Low Cost Suburban hotel
  • 125 rooms in property
~2.98 Miles from 46221
Crowne Plaza Indianapolis Airport in Indianapolis
+1-800-997-5148Check Rates
2501a South High School Rd., Indianapolis, IN 46241
  • Three Star Suburban property
  • 5 floors in hotel
~3.03 Miles from 46221
Crowne Plaza Indianapolis Airport
+1-800-997-5149Check Rates
2501 South High School Rd., Indianapolis, IN 46241
  • 4.0/5, Very Good Reviews
  • 3-star Airport hotel
  • Check-in time: 3 pm
~3.15 Miles from 46221
Radisson Hotel Indianapolis Airport - Indianapolis
+1-800-230-4134Check Rates
2500 South High School Rd., Indianapolis, IN 46241
  • 3.0/5, Average Reviews
  • 3-star Airport property
  • 258 sleeping rooms in hotel
~3.18 Miles from 46221
Hampton Inn & Suites Indianapolis Airport
+1-800-997-5148Check Rates
9020 Hatfield Dr., Indianapolis, IN 46231
  • 4.5/5, Very Good Hotel Reviews
  • 3 star Airport hotel
  • Gym / Fitness Center Available
~4.34 Miles from 46221
Comfort Inn South
+1-800-997-5149Check Rates
5040 South East St., Indianapolis, IN 46227
  • 3.0/5, Average Read Reviews
  • Inexpensive Highway hotel
  • Gym / Fitness Center Available
~4.83 Miles from 46221
Super 8 Indianapolis South : 450 Bixler Rd.
+1-800-230-4134Check Rates
450 Bixler Rd., Indianapolis, IN 46227
  • 2.5/5, Poor Reviews
  • Two-star Suburban hotel
  • Hotel has 100 rooms
~4.88 Miles from 46221
Holiday Inn Express South
+1-800-997-5148Check Rates
5151 South East St., Indianapolis, IN 46227
  • 4.0/5, Very Good Reviews
  • Mid-scale Highway property
  • Hotel has an eco-friendly policy Learn more
~4.89 Miles from 46221
Holiday Inn Express & Suites Indianapolis W Airpor : 5855 Rockville Rd.
+1-800-997-5149Check Rates
5855 Rockville Rd., Indianapolis, IN 46224
  • Two star Airport property
  • Gym / Fitness Center Available
~5.19 Miles from 46221
Microtel Inn & Suites by Wyndham Indianapolis Airp - Indianapolis
+1-800-230-4134Check Rates
5815 Rockville Rd., Indianapolis, IN 46224
  • 4.0/5, Very Good Review Score
  • 2 star Airport hotel
  • Check in: 03:00pm
~5.32 Miles from 46221
Wingate by Wyndham Airport - Indianapolis
+1-800-997-5148Check Rates
5797 Rockville Rd., Indianapolis, IN 46224
  • 4.0/5, Very Good Recent Reviews
  • Three Star Airport hotel
  • 3 floors in hotel
~5.32 Miles from 46221
Motel 6 - Indianapolis
+1-800-997-5149Check Rates
5845 Rockville Rd., Indianapolis, IN 46224
  • 3.5/5, Average Guest Reviews
  • Economical Airport hotel
  • Comp. Breakfast
~5.32 Miles from 46221
Value Place Indianapolis (Rockville) - Indianapolis
+1-800-230-4134Check Rates
8045 Rockville Rd., Indianapolis, IN 46214
  • 2.5/5, Poor Reviews
  • Economy hotel
  • Hotel has 41 suites
~6.11 Miles from 46221
Homewood Suites Airport Plainfield : 2264 East Perry Rd.
+1-800-997-5148Check Rates
2264 East Perry Rd., Plainfield, IN 46168
  • 4.5/5, Very Good Reviews
  • Mid-scale Airport property
  • Fitness / Gym is on-site
~6.19 Miles from 46221
Staybridge Suites Downtown Indianapolis Convention
+1-800-997-5149Check Rates
535 South West St., Indianapolis, IN 46225
  • 4.0/5, Very Good Latest Reviews
  • Three Star Downtown property
  • 113 rooms in hotel
~6.22 Miles from 46221
Comfort Suites City Centre : 515 South West St.
+1-800-230-4134Check Rates
515 South West St., Indianapolis, IN 46225
  • 3-star Downtown hotel
  • Hotel has 130 rooms
~6.25 Miles from 46221
Holiday Inn Express Indianapolis Downtown Conventi
+1-800-997-5148Check Rates
410 South Missouri St., Indianapolis, IN 46225
  • 4.0/5, Very Good Hotel Reviews
  • Mid-scale Downtown property
  • 6 floors in property
~6.36 Miles from 46221
La Quinta in Plainfield
+1-800-997-5149Check Rates
2251 Manchester Dr., Plainfield, IN 46168
  • 4.5/5, Very Good Recent Reviews
  • Affordable Airport property
  • Hotel has 2 meeting rooms
~6.45 Miles from 46221
Fairfield Inn & Suites Downtown Indianapolis - Indianapolis
+1-800-230-4134Check Rates
501 West Washington St., Indianapolis, IN 46204
  • 4.0/5, Very Good Guest Reviews
  • 3-star Downtown property
  • 8 floors in property
~6.58 Miles from 46221
Comfort Inn
+1-800-997-5148Check Rates
3514 South Keystone Ave., Indianapolis, IN 46227
  • 4.0/5, Very Good Recent Reviews
  • Three Star Downtown property
  • Hotel has 2 floors
~6.58 Miles from 46221
JW Marriott Indianapolis in Indianapolis
+1-800-997-5149Check Rates
10 South West St., Indianapolis, IN 46204
  • Luxury Five Star hotel
~6.59 Miles from 46221
Springhill Suites by Marriott Indianapolis Downtow - Indianapolis
+1-800-230-4134Check Rates
601a West Washington St., Indianapolis, IN 46204
  • 4.5/5, Very Good Latest Reviews
  • Mid-scale Downtown property
  • Free complimentary breakfast
~6.61 Miles from 46221
Crowne Plaza Downtown Indianapolis Union Station : 123 West Louisiana St.
+1-800-997-5148Check Rates
123 West Louisiana St., Indianapolis, IN 46225
  • 3.5/5, Average Recent Reviews
  • Four-star Downtown property
  • 273 rooms in property
~6.62 Miles from 46221
Courtyard by Marriott Indianapolis Downtown
+1-800-997-5149Check Rates
601 West Washington St., Indianapolis, IN 46204
  • 4.5/5, Very Good Review Score
  • Three Star Downtown hotel
  • 297 rooms in property
~6.63 Miles from 46221
Indianapolis Marriott Downtown
+1-800-230-4134Check Rates
350 West Maryland St., Indianapolis, IN 46225
  • Four-star Convention Center property
  • 21 suites in property
~6.65 Miles from 46221
Americas Best Value Inn
+1-800-997-5148Check Rates
3401 South Keystone Ave., Indianapolis, IN 46237
  • 2.5/5, Poor Guest Reviews
  • Economy Highway property
  • Complimentary breakfast is offered
~6.68 Miles from 46221
Omni Severin Hotel
+1-800-997-5149Check Rates
40 West Jackson Place, Indianapolis, IN 46225
  • 4.5/5, Very Good Hotel Reviews
  • High end Downtown property
  • 13 floors in property
~6.70 Miles from 46221
Hampton Inn Indianapolis Sw / Plainfield - Plainfield
+1-800-230-4134Check Rates
2244 East Perry Rd., Plainfield, IN 46168
  • 4.5/5, Very Good Recent Reviews
  • Mid-scale Airport property
  • 5 suites in property
~6.74 Miles from 46221
Le Meridien Indianapolis
+1-800-997-5148Check Rates
123 South Illinois St., Indianapolis, IN 46225~6.75 Miles from 46221
Homewood Suites Indianapolis Downtown
+1-800-997-5149Check Rates
211 South Meridian St., Indianapolis, IN 46225
  • 4.5/5, Very Good Review Score
  • 3 star Downtown property
  • 92 suites in property
~6.76 Miles from 46221
Hyatt Regency Indianapolis - Indianapolis
+1-800-230-4134Check Rates
1 South Capitol Ave., Indianapolis, IN 46204
  • 4.0/5, Very Good Recent Reviews
  • High end Downtown property
  • 30 meeting rooms in property
~6.78 Miles from 46221
The Alexander
+1-800-997-5148Check Rates
333 South Delaware St., Indianapolis, IN 46204
  • 4-star Downtown property
  • Check-in: 12:00 PM
~6.79 Miles from 46221
Embassy Suites Indianapolis Downtown - Indianapolis
+1-800-997-5149Check Rates
110 West Washington St., Indianapolis, IN 46204
  • 3.5/5, Average Latest Reviews
  • Mid-scale Downtown hotel
  • 13 floors in property
~6.87 Miles from 46221
University Place Conference Center & Hotel
+1-800-230-4134Check Rates
850 West Michigan St., Indianapolis, IN 46202
  • 3.5/5, Average Guest Reviews
  • High end Downtown hotel
  • Hotel has 10 floors
~6.87 Miles from 46221
Holiday Inn Express
+1-800-997-5148Check Rates
6296 Cambridge Way, Plainfield, IN 46168
  • 4.5/5, Very Good Hotel Reviews
  • 3-star Airport hotel
  • Free breakfast available
~6.88 Miles from 46221



Next: Show All Available 46221 Hotels with Pricing >