Star Rating
Hotel Name
Price Range (USD) to
Amenities
+ More

Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels/Motels & Accommodations

Super 8 by Wyndham Greenville 1700 State Route 127, Greenville, IL 62246
Call Us
  • Inexpensive Rural hotel
  • Check in time: 12:00 PM
More Photos Exterior of Super 8 by Wyndham Greenville
From$72 total
Average 3.0 /5 Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in Greenville" Get Alexa Skill →
SureStay by Best Western Greenville 1731 South State Route 127, Greenville, IL 62246
Call Us
  • Low Cost Highway hotel
  • Comp. Breakfast
More Photos Exterior of SureStay by Best Western Greenville
From$50 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites Greenville I-70 2265 South State Route 127, Greenville, IL 62246 Website
Call Us
  • 2-star Rural hotel
  • 3 floors in property
More Photos Image of Comfort Inn & Suites Greenville I-70
From$63 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Vandalia Il : 21 Mattes Ave. 21 Mattes Ave., Vandalia, IL 62471
Call Us
~15.52 miles east of Greenville
  • 3 star Highway property
  • Check-in: 3:00 PM
More Photos Photo of Holiday Inn Express & Suites Vandalia Il
From$96 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Ramada by Wyndham Vandalia 2707 Veterans Ave., Vandalia, IL 62471
Call Us
~15.77 miles east of Greenville
  • Low priced hotel
More Photos Photo of Ramada by Wyndham Vandalia
From$72 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn Vandalia 1500 North 6th St., Vandalia, IL 62471
Call Us
~17.45 miles east of Greenville
  • Low Cost Lake hotel
More Photos Exterior of Americas Best Value Inn Vandalia
From$60 total
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 in Vandalia 1920 North Kennedy Blvd., Vandalia, IL 62471 Website
Call Us
~17.57 miles east of Greenville
  • Two star Highway property
  • Free breakfast
More Photos Image of Quality Inn & Suites Vandalia near I-70 and Hwy 51
From$72 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 : 1920 Kennedy Blvd. 1920 Kennedy Blvd., Vandalia, IL 62471
Call Us
~17.59 miles east of Greenville
  • Cheap Rural property
  • 2 floors in hotel
More Photos Image of Quality Inn & Suites Vandalia near I-70 and Hwy 51
From$68 total
Very Good 4.5 /5 Reviews Call BookMore Details
Seasons Inn & Suites Highland : 20 Central Blvd. 20 Central Blvd., Highland, IL 62249
Call Us
~17.74 miles southwest of Greenville
  • Low Cost hotel
  • Fitness center on property
More Photos Photo of Seasons Inn & Suites Highland
From$78 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Mariner's Village Resort & Inn in Carlyle 1 Resort Dr., Carlyle, IL 62231
Call Us
~18.34 miles south of Greenville
  • Two star Lake hotel
  • Free breakfast
More Photos Image of Mariner's Village Resort & Inn
From$70 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Centerstone Inn & Suites : 1371 William Rd. 1371 William Rd., Carlyle, IL 62231
Call Us
~18.46 miles south of Greenville
  • 2 star property
  • Free breakfast available
More Photos Photo of Centerstone Inn & Suites
From$72 total
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Staunton 1527 Herman Rd., Staunton, IL 62088
Call Us
~21.09 miles west of Greenville
  • Two star property
  • Hotel has 3 suites
More Photos Image of Super 8 by Wyndham Staunton
From$60 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Innkeeper Motel 401 East State St., Hamel, IL 62046
Call Us
~23.07 miles west of Greenville
  • Midscale Lake property
  • Check-in: 2:00 PM
More Photos Image of Innkeeper Motel
From$96 total
Average 3.0 /5 Reviews Call BookMore Details
More Homes & Apts at Booking.com

Book online or call +1-800-219-2797

Booking for Homes and Apartments
Go to BookingGo to Booking
Americas Best Value Inn Litchfield 224 North Ohren Lane, Litchfield, IL 62056
Call Us
~24.10 miles northwest of Greenville
  • Low-priced property
  • Free complimentary breakfast
More Photos Exterior of Americas Best Value Inn Litchfield
From$72 total
Poor 2.0 /5 Latest Reviews Call BookMore Details
Motel 6 Litchfield, IL 211 Ohren Ln, Litchfield, IL 62056
Call Us
~24.16 miles northwest of Greenville
  • Cheap Highway property
More Photos Exterior of Motel 6 Litchfield, IL
From$72 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in Greenville" Get Alexa Skill →
Baymont by Wyndham Litchfield - Litchfield 1405 West Hudson Dr., Litchfield, IL 62056
Call Us
~24.16 miles northwest of Greenville
  • 2-star Highway hotel
  • Free complimentary breakfast
More Photos Image of Baymont by Wyndham Litchfield
From$72 total
Very Good 4.0 /5 Review Score Call BookMore Details
Quality Inn Litchfield Route 66 : 1010 East Columbian Blvd. North 1010 East Columbian Blvd. North, Litchfield, IL 62056 Website
Call Us
~24.37 miles northwest of Greenville
  • 2-star Downtown property
  • 15 suites in hotel
More Photos Image of Quality Inn Litchfield Route 66
From$84 total
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Hampton Inn Litchfield 11 Thunderbird Cir, Litchfield, IL 62056
Call Us
~24.48 miles northwest of Greenville
  • Three Star Highway hotel
  • Hotel has 3 floors
More Photos Photo of Hampton Inn Litchfield
From$96 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Litchfield West by IHG 4 Thunderbird Circle, Litchfield, IL 62056
Call Us
~24.49 miles northwest of Greenville
  • Mid-scale Rural hotel
  • Hotel has 22 suites
More Photos Photo of Holiday Inn Express & Suites Litchfield West by IHG
From$94 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Best Western Plus Centralia Hotel & Suites - Centralia 8145 Jolliff Bridge Rd., Centralia, IL 62801
Call Us
~28.09 miles southeast of Greenville
  • 3 star hotel
  • Check in: 03:00
More Photos Photo of Best Western Plus Centralia Hotel & Suites
From$93 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Americas Best Value Inn - Centralia 200 East Noleman, Centralia, IL 62801
Call Us
~29.09 miles southeast of Greenville
  • 2 star hotel
  • 57 rooms in property
More Photos Exterior of Americas Best Value Inn
From$72 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Motel 6 Troy Il 909 Edwardsville Rd., Troy, IL 62294
Call Us
~29.31 miles west of Greenville
  • Two star hotel
  • 2 floors in property
More Photos hotel room
From$60 total
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites Salem near I-57 in Salem 1800 West Main St., Salem, IL 62881 Website
Call Us
~29.38 miles southeast of Greenville
  • Cheap Rural property
  • 65 sleeping rooms in hotel
More Photos Photo of Quality Inn & Suites Salem near I-57
From$82 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Best Western Troy Hotel 2020 Formosa Rd., Troy, IL 62294
Call Us
~29.44 miles west of Greenville
  • 3-star Rural hotel
  • Free breakfast available
More Photos Photo of Best Western Troy Hotel
From$72 total
Average 3.5 /5 Guest Reviews Call BookMore Details
Holiday Inn Express Troy by IHG : 2011 Formosa Rd. 2011 Formosa Rd., Troy, IL 62294
Call Us
~29.51 miles west of Greenville
  • Affordable Highway hotel
  • Hotel has an eco-friendly policy Learn more
More Photos Image of Holiday Inn Express Troy by IHG
From$100 total
Very Good 4.5 /5 Read Reviews Call BookMore Details
Red Roof Inn St Louis - Troy, IL 2030 Formosa Rd., Troy, IL 62294
Call Us
~29.55 miles west of Greenville
  • Low Cost hotel
  • 8 suites in property
More Photos Photo of Red Roof Inn St Louis - Troy, IL
From$63 total
Very Good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Salem, Illinois - Salem 1812 West Main St., Salem, IL 62881
Call Us
~29.55 miles southeast of Greenville
  • Cheap hotel
  • Gym is available on property
More Photos Exterior of Days Inn by Wyndham Salem, Illinois
From$56 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Troy IL/St. Louis Area 910 Edwardsville Rd., Troy, IL 62294
Call Us
~29.60 miles west of Greenville
  • Economical Highway property
  • Comp. Breakfast
More Photos Photo of Super 8 by Wyndham Troy IL/St. Louis Area
From$75 total
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Salem 118 Woods Ln, Salem, IL 62881
Call Us
~29.63 miles southeast of Greenville
  • Low-priced Highway property
  • Free complimentary breakfast
More Photos Photo of Super 8 by Wyndham Salem
From$72 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Magnuson Grand Hotel And Conference Center in Raymond 19067 West Frontage Rd., Raymond, IL 62560
Call Us
~29.70 miles northwest of Greenville
  • Mid-scale Rural hotel
  • Check-in: 3:00 PM
More Photos Photo of Magnuson Grand Hotel And Conference Center
From$58 total
Very Good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Salem by IHG 102 Holiday Lane, Salem, IL 62881
Call Us
~29.89 miles southeast of Greenville
  • Affordable Highway hotel
  • 86 rooms in hotel
More Photos Exterior of Holiday Inn Express & Suites Salem by IHG
From$104 total
Excellent 5.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Edwardsville by IHG 1000 Plummer Dr., Edwardsville, IL 62025
Call Us
~31.59 miles west of Greenville
  • Three Star Suburban hotel
  • 18 suites in hotel
More Photos Image of Holiday Inn Express & Suites Edwardsville by IHG
From$112 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Country Hearth Inn & Suites Edwardsville St. Louis : 1013 Plummer Dr. 1013 Plummer Dr., Edwardsville, IL 62025
Call Us
~31.66 miles west of Greenville
  • Affordable Rural hotel
  • Check-in: 15:00
More Photos Photo of Country Hearth Inn & Suites Edwardsville St. Louis
From$80 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
TownePlace Suites by Marriott St. Louis Edwardsville, IL in Edwardsville 6101 Center Grove Rd., Edwardsville, IL 62025
Call Us
~31.67 miles west of Greenville
  • Affordable Suburban property
  • Fitness / Gym is on-site
More Photos Exterior of TownePlace Suites by Marriott St. Louis Edwardsville, IL
From$108 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Best Western Plus MidAmerica Hotel 9730 Hayden Dr., Mascoutah, IL 62258
Call Us
~32.05 miles southwest of Greenville
  • Mid-scale Suburban hotel
  • 15 suites in property
More Photos Photo of Best Western Plus MidAmerica Hotel
From$82 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Okawville 812 North Henhouse Rd., Okawville, IL 62271
Call Us
~32.28 miles south of Greenville
  • Low-priced Rural property
  • 2 suites in property
More Photos Photo of Super 8 by Wyndham Okawville
From$76 total
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Okawville in Okawville 812 North Hen House Rd., Okawville, IL 62271
Call Us
~32.28 miles south of Greenville
  • 2-star hotel
More Photos Image of Super 8 by Wyndham Okawville
From$72 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham O'fallon 1100 Eastgate Dr., Ofallon, IL 62269
Call Us
~33.41 miles southwest of Greenville
  • Low-priced Suburban property
  • 81 sleeping rooms in hotel
More Photos Image of Super 8 by Wyndham O'fallon
From$48 total
Average 3.0 /5 Reviews Call BookMore Details
Comfort Inn Edwardsville - St. Louis in Edwardsville 3080 South State Rte 157, Edwardsville, IL 62025
Call Us
~33.44 miles west of Greenville
  • 2-star Highway hotel
  • Gym is available on property
More Photos Exterior of Comfort Inn Edwardsville - St. Louis
From$72 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn Edwardsville 3080 Il 157, Edwardsville, IL 62025
Call Us
~33.44 miles west of Greenville
  • Affordable Highway hotel
  • Free comp. breakfast
More Photos Exterior of Comfort Inn Edwardsville
From$96 total
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites St. Louis Edwardsville : 5723 Heritage Crossing Dr. 5723 Heritage Crossing Dr., Glen Carbon, IL 62034
Call Us
~33.74 miles west of Greenville
  • 3 star Suburban hotel
  • Free complimentary breakfast
More Photos Exterior of Hampton Inn & Suites St. Louis Edwardsville
From$118 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Best Western U. S. Inn - Nashville 11640 State Route 127, Nashville, IL 62263
Call Us
~35.22 miles south of Greenville
  • Mid-scale Highway hotel
  • 2 floors in hotel
More Photos Photo of Best Western U. S. Inn
From$76 total
Very Good 4.0 /5 Reviews Call BookMore Details
Sleep Inn O Fallon Il in O'fallon 140 Venita Dr., O'fallon, IL 62269
Call Us
~35.35 miles southwest of Greenville
  • Three Star Suburban property
  • 71 sleeping rooms in hotel
More Photos Image of Sleep Inn O Fallon Il
From$96 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites O'fallon / Shiloh An Ihg Hotel - Shiloh 3396 Green Mount Crossing, Shiloh, IL 62269
Call Us
~35.48 miles southwest of Greenville
  • Affordable Highway hotel
  • Hotel has 80 rooms
More Photos Photo of Holiday Inn Express & Suites O'fallon / Shiloh An Ihg Hotel
From$118 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn & Suites Ofallon St. Louis Area 116 Regency Park, O'fallon, IL 62269
Call Us
~35.51 miles southwest of Greenville
  • Two-star Suburban property
  • Check-in time: 3:00 PM
More Photos Exterior of Comfort Inn & Suites Ofallon St. Louis Area
From$72 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn O'fallon Il - O'fallon 430 Regency Park, O'fallon, IL 62269
Call Us
~35.57 miles southwest of Greenville
  • Midscale Suburban hotel
  • Check in: 3:00pm
More Photos Image of Hampton Inn O'fallon Il
From$96 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis - O'fallon 136 Regency Park, O'fallon, IL 62269
Call Us
~35.59 miles southwest of Greenville
  • Two star Suburban hotel
  • Access to gym on-site
More Photos Exterior of La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis
From$72 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Hilton Garden Inn St. Louis Shiloh / O'fallon Il 360 Regency Park, O'fallon, IL 62269
Call Us
~35.65 miles southwest of Greenville
  • 3-star Suburban property
  • 20 suites in hotel
More Photos Exterior of Hilton Garden Inn St. Louis Shiloh / O'fallon Il
From$96 total
Average 3.0 /5 Review Score Call BookMore Details
Extended Stay America Select Suites - St. Louis - O' Fallon, IL - O'fallon 154 Regency Park, O'fallon, IL 62269
Call Us
~35.68 miles southwest of Greenville
  • Inexpensive Highway property
  • Check in: 3:00 PM
More Photos Photo of Extended Stay America Select Suites - St. Louis - O' Fallon, IL
From$46 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Welcome Suites 148 Regency Park, O'fallon, IL 62269
Call Us
~35.68 miles southwest of Greenville
  • Two-star Suburban hotel
  • Check in: 3:00 PM
More Photos Photo of Welcome Suites
From$48 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details

Next: See My Greenville Hotels with Pricing

Graph: Upcoming 20 Days of Greenville Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Greenville, IL discounts available. The chart reflects the cheapest Greenville hotel for each day and each star rating category.

FAQs about hotels in Greenville

What are the top reviewed hotels in Greenville?

Holiday Inn Express & Suites Salem by IHG, Quality Inn & Suites Vandalia near I-70 and Hwy 51 and Quality Inn Litchfield Route 66 are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Greenville?

Holiday Inn Express & Suites Vandalia Il, Innkeeper Motel and Hampton Inn Litchfield are the top 3 luxury hotels near Greenville city center.

What hotels are closest to the city center of Greenville?

Super 8 by Wyndham Greenville, SureStay by Best Western Greenville, and Comfort Inn & Suites Greenville I-70 are the properties closest to Greenville city center.

What are the best independent hotels in Greenville?

Mariner's Village Resort & Inn, Magnuson Grand Hotel And Conference Center and Welcome Suites are the best rated independent hotels (not part of a big brand).

What are the most popular Choice Hotels branded hotels in Greenville?

Quality Inn & Suites Vandalia near I-70 and Hwy 51, Quality Inn Litchfield Route 66 and Comfort Inn & Suites Greenville I-70 are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular Best Western hotels in Greenville?

Best Western Plus Centralia Hotel & Suites, Best Western Plus MidAmerica Hotel and Best Western U. S. Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the most popular IHG hotels in Greenville?

Holiday Inn Express & Suites Salem by IHG, Holiday Inn Express Troy by IHG and Holiday Inn Express & Suites Litchfield West by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Pizza slices at Casey's was very good"
Score 5.0 / 5

Akia S., from 12-Jul-2026
"Quiet town"
Score 4.0 / 5

Quiet town and my Son plays Basketball for Greenville university.

Newton A., from 26-Feb-2026
"Great Diner!"
Score 4.0 / 5

Vicky's Cafe was awesome!! Very helpful and polite staff! Clean diner with great food!

Amy S., from 24-Aug-2025
"Dressed up Strip area."
Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025
"Quiet Area"
Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024
"Proximity to Carlyle"
Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024
"Greenville has some excellent museums!"
Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023
"Great Aquarium"
Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023
"College Campus"
Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023
"Loved It!"
Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022
The average traveler rating of the city of Greenville, IL shown above is 4.4 out of 5 based on 10 reviews
Back to Top