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Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels/Accommodations

DoubleTree by Hilton Collinsville - St. Louis 1000 Eastport Plaza Dr, Collinsville, IL 62234 ~36.10 miles west of Greenville
  • Expensive hotel
  • 236 rooms in hotel
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Very Good 8.2 /10 Guest Reviews Call BookMore Details
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Fairfield Inn & Suites by Marriott OFallon IL 1180 Central Park Drive, O'Fallon, IL 62269 ~35.94 miles southwest of Greenville
  • Affordable property
  • Check in time: 3:00 PM
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Excellent 9.2 /10 Review Score Call BookMore Details
TownePlace Suites by Marriott St. Louis Edwardsville IL 6101 Center Grove Road, Edwardsville, IL 62025 ~31.77 miles west of Greenville
  • Three Star hotel
  • 18 suites in property
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Excellent 9.0 /10 Review Score Call BookMore Details
Hilton Garden Inn St. Louis Shiloh / OFallon IL 360 Regency Park Drive, O'Fallon, IL 62269 ~35.77 miles southwest of Greenville
  • 3-star hotel
  • 20 suites in hotel
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Very Good 8.0 /10 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Edwardsville by IHG 1000 Plummer Drive, Edwardsville, IL 62025 ~31.70 miles west of Greenville
  • Midscale hotel
  • Hotel has 4 floors
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Excellent 9.2 /10 Guest Reviews Call BookMore Details
Hampton Inn OFallon 430 Regency Park, O'Fallon, IL 62269 ~35.65 miles southwest of Greenville
  • Mid-scale hotel
  • Pets are Welcome
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Excellent 9.2 /10 Latest Reviews Call BookMore Details
Fairfield Inn & Suites St. Louis Pontoon Beach / Granite City 5224 Commerce Parkway, Granite City, IL 62040 ~37.34 miles west of Greenville
  • 3 star hotel
  • Fitness / Gym is on-site
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Excellent 9.2 /10 Read Reviews Call BookMore Details
Holiday Inn St. Louis Fairview Heights by IHG 313 Salem Place, Fairview Heights, IL 62208 ~37.06 miles southwest of Greenville
  • Mid-scale property
  • 88 sleeping rooms in hotel
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Very Good 8.6 /10 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites OFallon / Shiloh by IHG 3396 Green Mount Crossing Dr. Shiloh, O'Fallon, IL 62269 ~35.56 miles southwest of Greenville
  • Affordable property
  • Gym / Fitness Center Available
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Very Good 8.4 /10 Reviews Call BookMore Details
Holiday Inn Express Troy by IHG 2011 Formosa Road, Troy, IL 62294 ~29.58 miles west of Greenville
  • Midscale hotel
  • 18 suites in hotel
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Excellent 9.4 /10 Reviews Call BookMore Details
Radisson Hotel Fairview Heights - St. Louis 319 Fountains Pkwy, Fairview Heights, IL 62208 ~36.98 miles southwest of Greenville
  • Mid-scale hotel
  • Check in time: 3:00 PM - anytime
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Average 7.7 /10 Recent Reviews Call BookMore Details
Hampton Inn Collinsville 7 Commerce Drive, Collinsville, IL 62234 ~35.89 miles west of Greenville
  • 3 star hotel
  • 72 rooms in property
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Very Good 8.4 /10 Review Score Call BookMore Details
Hampton Inn & Suites St. Louis-Edwardsville 5723 Heritage Crossing Dr, Glen Carbon, IL 62034 ~33.80 miles west of Greenville
  • Mid-scale hotel
  • Check in: 3:00 PM - anytime
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Average 7.6 /10 Reviews Call BookMore Details
TownePlace Suites by Marriott St. Louis OFallon 445 REGENCY PARK DRIVE, O'Fallon, IL 62269 ~35.76 miles southwest of Greenville
  • 3-star hotel
  • 5 floors in hotel
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Excellent 9.0 /10 Review Score Call BookMore Details
Best Western St. Louis Fairview Heights 150 Ludwig Dr, Fairview Heights, IL 62208 ~37.70 miles southwest of Greenville
  • Three Star property
  • 61 sleeping rooms in hotel
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Poor 5.9 /10 Recent Reviews Call BookMore Details
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Country Hearth Inn & Suites Edwardsville St. Louis 1013 Plummer Drive, Edwardsville, IL 62025 ~31.77 miles west of Greenville
  • Affordable property
  • Gym is available on property
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Very Good 8.6 /10 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham Pontoon Beach 14 Regency Park Dr, Granite City, IL 62040 ~37.40 miles west of Greenville
  • Midscale hotel
  • Hotel has 65 rooms
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Very Good 8.4 /10 Hotel Reviews Call BookMore Details
The Great Rivers an Ascend Collection Hotel 3559 College Avenue, Alton, IL 62002 ~39.14 miles west of Greenville
  • Three Star hotel
  • Airport shuttle provided
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Average 7.8 /10 Read Reviews Call BookMore Details
Fairfield Inn by Marriott St. Louis Collinsville IL 4 Gateway Dr, Collinsville, IL 62234 ~36.03 miles west of Greenville
  • 3-star property
  • Pets Welcome
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Very Good 8.2 /10 Review Score Call BookMore Details
Comfort Suites Fairview Heights - St. Louis 137 Ludwig Dr, Fairview Heights, IL 62208 ~37.65 miles southwest of Greenville
  • 3-star hotel
  • Hotel has 3 floors
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Average 6.2 /10 Read Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis 6 Gateway Dr, Collinsville, IL 62234 ~36.09 miles west of Greenville
  • Mid-scale hotel
  • Hotel has an eco-friendly policy Read more
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Average 7.8 /10 Hotel Reviews Call BookMore Details
Country Inn & Suites by Radisson Fairview Heights, IL 140 Ludwig Drive, Fairview Heights, IL 62208 ~37.66 miles southwest of Greenville
  • Midscale hotel
  • Check-in time: 3:00 PM - 1:00 AM
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Average 7.0 /10 Review Score Call BookMore Details
Best Western Plus Pontoon Beach 4 Regency Pkwy, Granite City, IL 62040 ~37.43 miles west of Greenville
  • Three Star hotel
  • 3 floors in property
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Very Good 8.4 /10 Recent Reviews Call BookMore Details
Comfort Inn Edwardsville - St. Louis 3080 South State Route 157, Edwardsville, IL 62025 ~33.56 miles west of Greenville
  • Three Star property
  • Pets Welcome
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Very Good 8.4 /10 Latest Reviews Call BookMore Details
Candlewood Suites O Fallon by IHG 1332 Park Plaza Dr, O'Fallon, IL 62269 ~35.98 miles southwest of Greenville
  • Three Star property
  • 4 floors in property
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Average 7.8 /10 Guest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham OFallon IL - St. Louis 136 Regency Park, O'Fallon, IL 62269 ~35.67 miles southwest of Greenville
  • Three Star hotel
  • Check-in: 3:00 PM - anytime
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Poor 5.4 /10 Latest Reviews Call BookMore Details
Best Western Plus MidAmerica Hotel 9730 Hayden Drive, Mascoutah, IL 62258 ~32.12 miles southwest of Greenville
  • Affordable hotel
  • 3 floors in property
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Excellent 9.0 /10 Hotel Reviews Call BookMore Details
Innkeeper Motel 401 East State Street, Hamel, IL 62046 ~23.14 miles west of Greenville
  • Two-star Motel property
  • Check in: 2:00 PM
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Average 6.3 /10 Read Reviews Call BookMore Details
Best Western Troy Hotel 2020 Formosa Drive, Troy, IL 62294 ~29.56 miles west of Greenville
  • Mid-scale hotel
  • Fitness + Health Center
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Very Good 8.0 /10 Latest Reviews Call BookMore Details
Spark by Hilton Troy 2020 Formosa Rd, Troy, Illinois 62294 ~29.56 miles west of Greenville
  • Affordable property
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Average 7.2 /10 Recent Reviews Call BookMore Details
Days Inn & Suites by Wyndham Caseyville 2423 Old Country Inn Drive, Caseyville, IL 62232 ~39.77 miles west of Greenville
  • Mid-scale property
  • Pets are OK
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Poor 4.0 /10 Reviews Call BookMore Details
Comfort Inn Collinsville near St. Louis 8 Commerce Dr, Collinsville, IL 62234 ~35.86 miles west of Greenville
  • 3-star hotel
  • Hotel has 80 rooms
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Very Good 8.6 /10 Reviews Call BookMore Details
Extended Stay America Select Suites - St. Louis - O Fallon IL 154 Regency Park, O'Fallon, IL 62269 ~35.74 miles southwest of Greenville
  • Three Star property
  • 89 rooms in hotel
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Average 7.6 /10 Recent Reviews Call BookMore Details
Sleep Inn OFallon near I-64 140 Venita Dr, O'Fallon, IL 62269 ~35.43 miles southwest of Greenville
  • Three Star property
  • Hotel has 71 rooms
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Average 6.8 /10 Review Score Call BookMore Details
Hampton Inn & Suites St. Louis / Alton 1904 Homer M Adams Parkway, Alton, IL 62002 ~40.87 miles west of Greenville
  • Midscale property
  • Free complimentary breakfast
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Excellent 9.0 /10 Hotel Reviews Call BookMore Details
Quality Inn & Suites Caseyville - St. Louis 2180 Patricia Dr, Caseyville, IL 62232 ~39.68 miles west of Greenville
  • Mid-scale hotel
  • Check in time: 3:00 PM - anytime
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Poor 5.8 /10 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Vandalia by IHG 21 Mattes Ave, Vandalia, IL 62471 ~15.58 miles east of Greenville
  • Midscale property
  • Pet-friendly
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Very Good 8.8 /10 Read Reviews Call BookMore Details
Days Inn by Wyndham Pontoon Beach 5105 Highway 111, Granite City, IL 62040 ~37.31 miles west of Greenville
  • Two-star hotel
  • Hotel has 2 floors
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Average 6.2 /10 Reviews Call BookMore Details
Holiday Inn Express & Suites Salem by IHG 102 Holiday Lane, Salem, IL 62881 ~29.96 miles southeast of Greenville
  • Three Star property
  • 15 suites in hotel
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Excellent 9.4 /10 Reviews Call BookMore Details
Holiday Inn Express and Suites Alton St. Louis Area by IHG 2008 HOMER ADAMS PARKWAY, Alton, IL 62002 ~40.74 miles west of Greenville
  • Three Star hotel
  • Check-in: 3:00 PM - midnight
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Excellent 9.0 /10 Recent Reviews Call BookMore Details
Best Western Plus Centralia Hotel & Suites 8145 Jolliff Bridge Rd, Centralia, IL 62801 ~28.10 miles southeast of Greenville
  • 3 star hotel
  • Free breakfast
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Excellent 9.6 /10 Hotel Reviews Call BookMore Details
Quality Inn OFallon - St. Louis - Shiloh 1409 West US 50, O'Fallon, IL 62269 ~36.16 miles southwest of Greenville
  • Mid-scale property
  • Pets/Animals Allowed
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Average 7.4 /10 Review Score Call BookMore Details
Super 8 by Wyndham Fairview Heights-St. Louis 45 Ludwig Dr, Fairview Heights, IL 62208 ~37.32 miles southwest of Greenville
  • Low Cost hotel
  • Check-in: 3:00 PM - 5:00 AM
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Average 6.4 /10 Read Reviews Call BookMore Details
Red Roof Inn St. Louis - Troy IL 2030 Formosa Road, Troy, IL 62294 ~29.56 miles west of Greenville
  • Two star property
  • Hotel has 72 rooms
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Average 7.8 /10 Latest Reviews Call BookMore Details
Best Western Plus Parkway Hotel 1900 Homer Adams Pkwy, Alton, IL 62002 ~40.86 miles west of Greenville
  • 3 star hotel
  • Fitness / Gym is on-site
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Very Good 8.2 /10 Read Reviews Call BookMore Details
Royal Relax Inn 5280 Collinsville Rd, Fairmont City, IL 62201 ~40.67 miles west of Greenville
  • 3 star Motel property
  • Hotel has 43 rooms
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Average 6.0 /10 Latest Reviews Call BookMore Details
Econo Lodge Inn & Suites Granite City - St. Louis 3236 West Chain of Rocks Rd, Granite City, IL 62040 ~39.67 miles west of Greenville
  • Low Cost property
  • Free breakfast available
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Average 6.4 /10 Latest Reviews Call BookMore Details
Comfort Inn Alton near I-255 11 Crossroads Ct, Alton, IL 62002 ~39.22 miles west of Greenville
  • 3 star property
  • Free complimentary breakfast
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Average 7.4 /10 Review Score Call BookMore Details
Red Lion Inn & Suites Pontoon Beach 1240 East Chain of Rocks Rd, Granite City, IL 62040 ~36.92 miles west of Greenville
  • Affordable hotel
  • Hotel has 53 rooms
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Average 7.8 /10 Latest Reviews Call BookMore Details
Days Inn by Wyndham Collinsville / St. Louis 12 Commerce Drive, Collinsville, IL 62234 ~35.87 miles west of Greenville
  • Mid-scale property
  • Pets/Dogs Allowed
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Average 7.4 /10 Latest Reviews Call BookMore Details

Next: See My Greenville Hotels with Pricing

FAQs about hotels in Greenville

What are the most favored hotels in Greenville?

Best Western Plus Centralia Hotel & Suites, Holiday Inn Express Troy by IHG and Holiday Inn Express & Suites Salem by IHG are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels in Greenville?

DoubleTree by Hilton Collinsville - St. Louis, TownePlace Suites by Marriott St. Louis Edwardsville IL and Fairfield Inn & Suites by Marriott OFallon IL are the top 3 luxury hotels near Greenville city center.

What hotels are closest to the city center of Greenville?

Holiday Inn Express & Suites Vandalia by IHG, Innkeeper Motel, and Best Western Plus Centralia Hotel & Suites are the properties closest to Greenville city center.

What are the best independent hotels in Greenville?

Historic Red Rooster Inn, Altamont Motel and Lighthouse Lodge are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels in Greenville?

Fairfield Inn & Suites St. Louis Pontoon Beach, Fairfield Inn & Suites by Marriott OFallon IL and TownePlace Suites by Marriott St. Louis Edwardsville IL are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels in Greenville?

Comfort Inn Collinsville near St. Louis, Quality Inn Litchfield Route 66 and Comfort Inn Edwardsville - St. Louis are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best Best Western hotels in Greenville?

Best Western Plus Centralia Hotel & Suites, Best Western Plus MidAmerica Hotel and Best Western U. S. Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the most popular IHG hotels in Greenville?

Holiday Inn Express & Suites Litchfield West by IHG, Holiday Inn Express Troy by IHG and Holiday Inn Express & Suites Salem by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Pizza slices at Casey's was very good"
Score 5.0 / 5

Akia S., from 12-Jul-2026
"Quiet town"
Score 4.0 / 5

Quiet town and my Son plays Basketball for Greenville university.

Newton A., from 26-Feb-2026
"Great Diner!"
Score 4.0 / 5

Vicky's Cafe was awesome!! Very helpful and polite staff! Clean diner with great food!

Amy S., from 24-Aug-2025
"Dressed up Strip area."
Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025
"Quiet Area"
Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024
"Proximity to Carlyle"
Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024
"Greenville has some excellent museums!"
Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023
"Great Aquarium"
Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023
"College Campus"
Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023
"Loved It!"
Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022
The average traveler rating of the city of Greenville, IL shown above is 4.4 out of 5 based on 10 reviews
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