Holiday Inn Express & Suites St. Louis South - I-55 by IHG

4250 Midamerica Ln, St. Louis, MO 63129 United States (USA) near Exit 195 on I-55 (~0.2km)
View Map Reservations: 1-800-219-2797
2.5 Star Property
38.484450-90.354130
+1-800-219-2797
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Check availability
  • We have an indoor pool ready for use
  • Free breakfast
  • Fitness / Gym is on-site
  • 99 rooms in hotel
  • Hotel has 4 floors
  • Hotel has 17 suites
  • Check-in time: 3p
  • Has environment-friendly policy
  • Group booking rating of 9.4/10
  • 2 meeting rooms in hotel

Check Current Prices






Standard prices by room type for the next 60 days

Rates shown are nightly rates before taxes and do not necessarily reflect all discounts available. The chart provides the cheapest public rates available by room type.

Room Types

Check Rates1 Bedroom 2 Queen Beds Suite
Non-Smoking
Check Rates1 Bedroom Suite 2 Queen Beds
Non-Smoking
Check Rates1 Bedroom Suite 2 Queen Beds Living Area
Non-Smoking
Check Rates1 King Bed
Non-Smoking
Check Rates1 King Bed Accessible
Non-Smoking
Check Rates1 King Bed Accessible Comm Bath Shower Combo
Non-Smoking
Check Rates1 King Bed Accessible Comm Bath Shower Combo 1 King Bed
Non-Smoking
Check Rates1 King Bed Accessible Mobil Roll in Shower
Non-Smoking
Check Rates1 King Bed Accessible Suite
Non-Smoking
Check Rates1 King Bed Bath Shower Combo
Non-Smoking
Check Rates1 King Bed Bath Shower Combo 1 King Bed
Non-Smoking
Check Rates1 King Bed Mobility Accessible
Non-Smoking
Check Rates1 King Bed Mobility Accessible Roll in Shower
Non-Smoking
Check Rates1 King Bed Suite
Non-Smoking
Check Rates1 King Bed Suite Accessible
Non-Smoking
Check Rates1 King Standard Bath Shower Combo
Non-Smoking
Check Rates1 King Standard Bath Shower Combo 330 Sqft Standard Bath Shower Combo Microwave, Minifridge
Non-Smoking
Check Rates1 King Stndrd Comm Accessible Bath Shower Combo
Non-Smoking
Check Rates1 King Stndrd Comm Accessible Bath Shower Combo 325 Sqft Stndrd Comm Accessible Bath Shower Combo
Non-Smoking
Check Rates1 King Stndrd Mobility Accessible Roll in Shower
Non-Smoking
Check Rates1 King Stndrd Mobility Accessible Roll in Shower 325 Sqft Stndrd Mobility Accessible Roll in Shower
Non-Smoking
Check Rates1 King Suite Extra Living Walk in Shower
Non-Smoking
Check Rates1 King Suite Extra Living Walk in Shower 380 Sqft Suite Extra Living Walk in Shower Microwave
Non-Smoking
Check Rates1 King Suite Mobility Accessible Tub Extra Living
Non-Smoking
Check Rates1 King Suite Mobility Accessible Tub Extra Living 385 Sqft Suite Mobility Accessible Tub Extra Livin
Non-Smoking
Check Rates2 Bed Hearing Accessible
Non-Smoking
Check Rates2 Bed Mobility Accessible Tub
Non-Smoking
Check Rates2 Queen 1 Bedroom Suite Extra Living Area
Non-Smoking
Check Rates2 Queen 1 Bedroom Suite Extra Living Area 380 Sqft Suite Extra Living Area Microwave, Minifridge
Non-Smoking
Check Rates2 Queen Beds
Non-Smoking
Check Rates2 Queen Beds Accessible
Non-Smoking
Check Rates2 Queen Beds Accessible Comm Bath Shower Combo
Non-Smoking
Check Rates2 Queen Beds Accessible Comm Bath Shower Combo 2 Queen Bed
Non-Smoking
Check Rates2 Queen Beds Accessible Mobil Tub
Non-Smoking
Check Rates2 Queen Beds Mobility Accessible
Non-Smoking
Check Rates2 Queen Beds and Accessible Tub
Non-Smoking
Check Rates2 Queen Stndrd Comm Accessible Bath Shower Combo
Non-Smoking
Check Rates2 Queen Stndrd Comm Accessible Bath Shower Combo 325 Sqft Stndrd Comm Accessible Bath Shower Combo M
Non-Smoking
Check Rates2 Queen Stndrd Mobility Accessible Tub
Non-Smoking
Check Rates2 Queen Stndrd Mobility Accessible Tub 380 Sqft Stndrd Mobility Accessible Tub Microwave, Minifridge
Non-Smoking
Check RatesComm Accessible Standard 2 Queen Room with Bath Shower Combo
Non-Smoking
Check RatesComm Standard Room 2 Queen Beds Mobility Accessible
Non-Smoking
Check RatesDeluxe 1 King Bed
Non-Smoking
Check RatesDeluxe King Bed
Non-Smoking
Check RatesDeluxe King Room
Non-Smoking
Check RatesDouble 2 Queen Stndrd Accessible Tub
Non-Smoking
Check RatesKing Hearing Accessible
Non-Smoking
Check RatesKing Mobility Accessible Roll in Shower
Non-Smoking
Check RatesKing Room Disability Accessible
Non-Smoking
Check RatesKing Room Mobility Accessible Roll in Shower
Non-Smoking
Check RatesQueen Queen Accessible
Non-Smoking
Check RatesQueen Queen Accessible Tub
Non-Smoking
Check RatesQueen Room with 2 Queen Beds Disability Accessible
Non-Smoking
Check RatesStandard 2 Queen Beds Accessible
Non-Smoking
Check RatesStandard 2 Queen Beds Bath and Shower Accessible
Non-Smoking
Check RatesStandard Double Suite
Non-Smoking
Check RatesStandard King Bed Accessible
Non-Smoking
Check RatesStandard King Bed Bath and Shower
Non-Smoking
Check RatesStandard King Bed Bath and Shower Accessible
Non-Smoking
Check RatesStandard Room, King or Two Doubles
Non-Smoking
Check RatesStandard Suite
Non-Smoking
Check RatesStndrd Comm Room 2 Queen Beds
Non-Smoking
Check RatesStndrd Comm Room King Bed
Non-Smoking
Check RatesStndrd Room 2 Queen Beds Mobility Accessible
Non-Smoking
Check RatesStndrd Room King Bed Mobility Accessible
Non-Smoking
Check RatesSuite
Non-Smoking
Check RatesSuite 1 Bedroom 2 Queen Extra Living Area
Non-Smoking
Check RatesSuite 1 Bedroom Mobility Accessible Tub
Non-Smoking
Check RatesSuite 1 King Bed Accessible Mobil Tub Extra Living
Non-Smoking
Check RatesSuite 1 King Bed Extra Living Walk in Shower
Non-Smoking
Check RatesSuite Double Bed
Non-Smoking
Check RatesSuite King Bed Living Area
Non-Smoking
Check RatesSuite King Bed Living Area Accessible
Non-Smoking
Check RatesSuite King Bed Mobility Accessible
Non-Smoking

Local Attractions

Busch Stadium, Gateway Arch, Grant's Farm, Magic House, St. Louis Science Center, St. Louis Zoo, Forest Park, RiverCity Casino, and MUCH MORE!

Verified Reviews of Holiday Inn Express & Suites St. Louis South I 55 by IHG

Below are the verified reviews from guests that we have booked recently:
"Very clean very hospitable people that worked there overall great experience"
Overall Score5.0/ 5
I would recommend anybody who wants to go to a very nice clean good hotel with a great breakfast to Holiday Inn express.
(Individual traveler, booked 1 room), from US flag
23-Nov-2025 Verified Review, stayed from Sat Nov 22 to Sun Nov 23 2025 at a $141.99 average nightly rate.
"Great place to stay."
Overall Score5.0/ 5
We arrived late and Hailey was at the front desk. She was so nice and helpful. Very personable. The bed was very comfortable and our room was very clean.
(Individual traveler, booked 1 room), from US flag
30-Sep-2025 Verified Review, stayed from Sat Sep 27 to Sun Sep 28 2025 at a $181.46 average nightly rate.
"Great Experience"
Overall Score5.0/ 5
This was a very clean and quiet hotel. Good breakfast in the morning.
(Individual traveler, booked 1 room), from US flag
15-Sep-2025 Verified Review, stayed from Fri Sep 12 to Sat Sep 13 2025 at a $170.00 average nightly rate.
"Relaxing"
Overall Score5.0/ 5
Friendly staff and clean accommodations.
(Individual traveler, booked 1 room), from US flag
14-Jul-2025 Verified Review, stayed from Fri Jul 11 to Mon Jul 14 2025 at a $152.00 average nightly rate.
"Great staff, clean, quiet."
Overall Score5.0/ 5
We stayed at this Holiday Inn because it was located next door to a medical facility where my husband had appointments. It was a great stay, I woudn't hesitate to stay here again. The staff was extremely helpful, the room was spotless and the hotel was quiet, even tho there were a lot of people staying there. In the evening they put out warm cookies and milk. Would definitely recommend !
(Individual traveler, booked 1 room), from US flag
07-Jul-2025 Verified Review, stayed from Tue Jul 01 to Wed Jul 02 2025 at a $143.99 average nightly rate.
"Front desk personnel very nice and helpful."
Overall Score5.0/ 5
Facility very clean, good parking, nice large room. Loved the cookies in the evening. Very nice breakfast. We always try to book Holiday Inn when we travel because their standards are consistent. We know there services will be very good.
(Individual traveler, booked 1 room), from US flag
12-Jun-2025 Verified Review, stayed from Thu Jun 12 to Fri Jun 13 2025 at a $143.99 average nightly rate.
"Wonderful place to stay."
Overall Score5.0/ 5
Very clean hotel. Staff is great. Can't think of anything bad about this place!
(Individual traveler, booked 1 room), from US flag
14-May-2025 Verified Review, stayed from Tue May 13 to Thu May 15 2025 at a $169.00 average nightly rate.
"Wonderful!"
Overall Score5.0/ 5
Everything about this hotel is great. Clean, nicely furnished rooms, friendly and helpful staff, good breakfast.
(Individual traveler, booked 1 room), from US flag
02-May-2025 Verified Review, stayed from Sun Apr 27 to Wed Apr 30 2025 at a $130.00 average nightly rate.
"Better Than Excellent 7 of of 7."
Overall Score5.0/ 5
The room I got had a bed that too high for me to get into as I am disabled. I called the front desk, to see if the had a step stool. Julie at the front desk said no that it was a safety protocol but they did have Physical Handicap Room availiable with a walk in shower and a lower bed at no extra charge. The room was very large and really nice. The bed was much lower which I could easily get into. The walk in shower was great, no step at all and with the hand rails taking a shower was very easy and safe. Next time I'm in St. Louis, I hope this room is available, it made my stay so much more delightful. Even better, the free breakfast! Oh man I was in heaven. They have a "Pancake Maker" that makes the best pancakes you've ever tasted. They also have a sausage gravy that you must try, it's fantastic! Even better, at 8 pm they serve Free cookies, mouth watering chocolate chip cookies that are out of this world great! The staff was very friendly and bent over backwards to make my stay all that much better. Did I say 7 of 7, I meant 10 of 10!
(Individual traveler, booked 1 room), from US flag
13-Mar-2025 Verified Review, stayed from Tue Mar 11 to Thu Mar 13 2025 at a $177.49 average nightly rate.
"Very Nice Hotel"
Overall Score5.0/ 5
Very nice hotel.
(Individual traveler, booked 1 room), from US flag
13-Mar-2025 Verified Review, stayed from Tue Mar 11 to Thu Mar 13 2025 at a $153.99 average nightly rate.
"Awesome Rooms!"
Overall Score5.0/ 5
Room was clean and very large, breakfast was very good. Would stay there again.
(Individual traveler, booked 1 room), from US flag
10-Feb-2025 Verified Review, stayed from Fri Feb 07 to Sat Feb 08 2025 at a $125.00 average nightly rate.
"Very good, excellent."
Overall Score5.0/ 5
100% Recommended
(Individual traveler, booked 1 room), from US flag
23-Nov-2024 Verified Review, stayed from Wed Nov 20 to Thu Nov 21 2024 at a $125.00 average nightly rate.
"Great room, great breakfast."
Overall Score5.0/ 5
To our surprise, the room we rented was fabulous. Everything was updated. The morning breakfast was first rate. We will definitely stay again.
(Group coordinator, booked 2 rooms), from US flag
24-Sep-2024 Verified Review, stayed from Fri Sep 20 to Sat Sep 21 2024 at a $161.56 average nightly rate.

Property Description

The newest, most modern hotel in the area! The Holiday Inn Express & Suites St. Louis South I-55 is nestled within a growing development near the intersection of Highway 55 & Interstate 270. Located a short 14 miles from downtown St. Louis, in a great, safe location, minutes from dining/shopping/attractions.

Green Sustainability

Yes, ask the front desk about our Greener Stay program

Details / Other Expenses

Check In: 3p
Check Out: 11a
Year of Last Renovation: 2017
Floors: 4
Rooms: 99
Corridors: All Rooms Have Interior Hallways
Non Smoking Rooms: 99
Handicap Rooms:
Suites: 17
Room Windows: Windows Don't Open
Cleaning Frequency: Daily
Meeting Rooms: 2 View Spaces
Meeting Space: 65.2 sq. meters
Banquet Space: Holds 18 people
Dist. to Food/Bars: 0.4 Km
Dist. to 24hr Restaurant: 0.4 Km
Dist. to Nearest Gym: On-site
FEMA Approved: Yes
Pool Info: 8a - 10p
Ownership: Midamerica Hotels Corp
Policies / Expenses
Cancellation:
6p day of arrival
Nightly Parking: $0
Total Taxes: 14.99%
Total Misc Fees: ¥0.00 CNY
(mandatory resort fees/taxes)
State Tax: 7.74%
City Tax: 7.25%
Food and Beverage Tax: 7.74%
Food and Beverage Service Charge: 18.00%
Audio Visual Service Charge: 18.00%
Banquet Gallon of Coffee: 17.95 Per Item
Banquet Soda: 2.00 Per Item
Banquet Bottled Water: 2.00 Per Item

Amenities / Features


  • Air conditioning
  • Alarm clock
  • Baggage storage facilities
  • Bus parking
  • Central location
  • Clothes drying
  • Complimentary breakfast
  • Complimentary newspaper
  • Concierge service
  • Conference facilities
  • Credit card accepted: Mastercard/Visa
  • Credit card accepted: American Express
  • Credit card accepted: Discover
  • Electronic key card
  • Elevator
  • Express Check-Out
  • Facilities for the disabled
  • Fax available
  • Fitness and health center
  • Free local calls
  • Hairdryer available
  • Handicap accessible
  • Central heating
  • Ice Maker
  • Internet - wireless
  • Internet - ethernet
  • Free WiFi Internet
  • Ironing facilities
  • Laundry facilities
  • Laundry valet service
  • Movies in room
  • Microwave in room
  • Non-smoking rooms
  • 24 hours opened
  • Office or business center
  • Private bathroom in room
  • Quiet location
  • Radio in room
  • Refrigerator
  • Safe in rooms
  • Self controlled heating/cooling system
  • Shop
  • Shower
  • Swimming pool - indoor
  • Tea and coffee making facilities
  • Telephone
  • Telephone in all rooms
  • Telephone - Free local calls
  • Television
  • TV - Free Cable
  • Terrace
  • Voicemail

Airport & Shuttle Information

Lambert International Airport, 22 miles, $40 taxi

Airport Shuttle? Sorry, no airport shuttle available.

Breakfast Information

Express Start Breakfast is a full, hot buffet, included in all room rates. Make-your-own pancakes, serve up some eggs, meats, biscuits & gravy, oatmeal, cold cereal, yogurt, and much more!

Pet Friendly?

Service animals complying with ADA Title lll regulations are allowed.

Sorry, pets are not allowed.

Parking Info

Free, self-parking, on our surface lot, with plenty of room for buses, trucks, and trailers.

Internet / WiFI

FREE WiFi, wired & wireless, throughout the building

About Holiday Inn Express

  • Free Express Start Breakfast
  • Have their own 100% Arabica Smart Roast Coffee
  • Free high-speed internet service in every room
  • eHost Online Concierge Service where guests can learn about hotel amenities, major airlines nearby, up-to-date local weather and even car rental services
  • Perfect for the business traveler on the go, Holiday Inn Express offers 24/7 hours & photocopy services

The Holiday Inn Express highlights above are subject to change without notice.

Meeting Rooms and Banquet Rooms at Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Below are the meeting, banquet, conference and event spaces at Holiday Inn Express & Suites St. Louis South - I-55 by IHG.

Feel free to use the Holiday Inn Express & Suites St. Louis South - I-55 by IHG meeting space capacities chart below to help in your event planning. Hotel Planner specializes in St. Louis event planning for sleeping rooms and meeting space for corporate events, weddings, parties, conventions, negotiated rates and trade shows.

Meeting Room Name L x W x H
(Feet)
Size
(sqft.)
Banquet
5'/6'
Banquet Space Layout
Crescent
Crescent Tables Layout
Classroom
Classroom Meeting Layout
Hollow
Square
Hollow Square Table Layout
U-Shape
U Shape Meeting Layout
Boardroom
Boardroom Meeting Space
Convention
8'/10'
Convention Booth Layout
Theater
Theater Layout
Reception
Reception Desk for Meeting
Regist.
Desk
Registration Desk for Meeting
Jefferson Room 27 x 13 x 10 351--/----12----12--/--------
Close This

Jefferson Room

Perfect space for a smaller meeting, interviews, reviews, presentation, etc. Small counter & wet sink, in room. 80" flat panel, wall-mounted TV, with presentation table. Electric at classroom tables, for laptop use.
Room Type:
General Meeting Room
Total Size:
32.6 Sq. Km
Dimensions:
27 x 13 x 10 Ft.
Floor Level:
1
Columns:
0
Windows:
0
Natural Light?:
No
Obstructions?
No
Built In Screens?
No
Built In Stage?
No
Built In A/V?
No
Amenities Available
  • Coffee/Tea Setup
  • Food/Beverage
  • TV/VCR/DVD
  • WIFI Internet
  • White Board
  • Flip Chart
  • Air Conditioning
Half Day Rental:
$175.00 USD
Full Day Rental:
$175.00 USD
Evening Rental:
$175.00 USD
24 Hr. Hold Rental:
$175.00 USD
Photo of Jefferson Room
Mississippi Room 27 x 13 x 10 351--/----------18--/--------
Close This

Mississippi Room

This room sets off of the breakfast area and has large sliding barn doors, which block out sound. There is a small counter and 80" flat panel, wall-mounted TV, for presentation. Great for a board meeting, small training, interviews, reviews, etc.
Room Type:
Boardroom
Total Size:
32.6 Sq. Km
Dimensions:
27 x 13 x 10 Ft.
Floor Level:
1
Columns:
0
Windows:
1
Natural Light?:
Yes
Obstructions?
No
Built In Screens?
No
Built In Stage?
No
Built In A/V?
No
Amenities Available
  • Coffee/Tea Setup
  • Food/Beverage
  • TV/VCR/DVD
  • WIFI Internet
  • White Board
  • Flip Chart
  • Air Conditioning
Half Day Rental:
$150.00 USD
Full Day Rental:
$150.00 USD
Evening Rental:
$150.00 USD
24 Hr. Hold Rental:
$150.00 USD
Photo of Mississippi Room

FAQs about Holiday Inn Express & Suites St. Louis South I 55 by IHG

What time is check in?

Check in time is 3p based on the hotel's local time. Early check in may be available if requested at the front desk on the day of check-in.

What time is check out?

Check out time is 11a based on the hotel's local time. Late check out may be available if requested at the front desk during your stay.

How many rooms does Holiday Inn Express & Suites St. Louis South I 55 by IHG have?

There are 99 rooms in the property.

Is there any meeting space at Holiday Inn Express & Suites St. Louis South I 55 by IHG?

Yes, they have 2 meeting rooms that can support various table layouts.

What kind of breakfast is at Holiday Inn Express & Suites St. Louis South I 55 by IHG?

Express Start Breakfast is a full, hot buffet, included in all room rates. Make-your-own pancakes, serve up some eggs, meats, biscuits & gravy, oatmeal, cold cereal, yogurt, and much more!

What parking is available at Holiday Inn Express & Suites St. Louis South I 55 by IHG?

Free, self-parking, on our surface lot, with plenty of room for buses, trucks, and trailers.

How much does internet cost?

FREE WiFi, wired & wireless, throughout the building

Can I get a AAA rate at Holiday Inn Express & Suites St. Louis South I 55 by IHG?

Sorry, this hotel does not offer AAA hotel discounts at this time.

Can I get a Senior or AARP rate at Holiday Inn Express & Suites St. Louis South I 55 by IHG?

Sorry, this hotel does not offer senior hotel discounts at this time.

Is there a gym at Holiday Inn Express & Suites St. Louis South I 55 by IHG?

Yes, there is a gym/fitness area available on-site at the property.

Is there a pool at Holiday Inn Express & Suites St. Louis South I 55 by IHG?

Yes, there is a pool on-site at the property. 8a - 10p.

Testimonials:

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