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Santa Isabel Puerto Rico Hotels & Motels

Find accommodations in Santa Isabel with the hotel list provided below. Explore our guide for inexpensive and discount hotel/motel rates in or near Santa Isabel, Puerto Rico for your personal leisure or group travel. Explore the most favored Santa Isabel hotel and motel rooms. Browse the Santa Isabel area hotels to find the perfect lodging! Please use the provided map of the Santa Isabel hotels.

The Santa Isabel center is around 11 miles east of Ponce Mercedita Airport and 14 miles southwest of San Cristobal Canyon.

Santa Isabel Hotels/Motels & Accommodations

Marina de Salinas - Salinas Pr 701 End, Salinas, 00751
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~6.16 miles east of Santa Isabel
  • Midscale property
  • 32 rooms in property
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From$108 total
Poor 2.5 /5 Latest Reviews Call BookMore Details
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Caribe Hotel Ponce in Ponce 103 Turpo Industrial Park, Ponce, 00715 Puerto Rico
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~12.64 miles west of Santa Isabel
  • Low Cost property
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From$72 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Spark by Hilton Ponce - Ponce 103 Turpo Industrial Park, Ponce, 715 Puerto Rico
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~12.64 miles west of Santa Isabel
  • 2-star property
  • Check-in: 12:00 PM
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From$72 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hilton Ponce Golf & Casino Resort - Ponce 1150 Caribe Ave., Ponce, 00716 Puerto Rico
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~14.24 miles west of Santa Isabel
  • High end Oceanfront property
  • 5 floors in property
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From$202 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Aloft Ponce St. 2 Km 228 9, Ponce, 00717
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~14.35 miles west of Santa Isabel
  • Mid-scale hotel
  • Check in: 15:00
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From$108 total
Average 3.0 /5 Reviews Call BookMore Details
Meliá Century Hotel Ponce in Ponce #75 Calle Cristina, Ponce, 00733 Puerto Rico
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~15.09 miles west of Santa Isabel
  • Three Star Downtown property
  • 70 rooms in property
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From$82 total
Average 3.5 /5 Latest Reviews Call BookMore Details
Ponce Plaza Hotel & Casino : Reina St. Reina St., Ponce, 00731 Puerto Rico
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~15.16 miles west of Santa Isabel
  • 3 star Downtown hotel
  • 4 floors in property
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From$142 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Ponce & Tropical Casino by IHG 3315 Ponce by Pass, Ponce, 00728 Puerto Rico
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~18.48 miles west of Santa Isabel
  • Midscale Mountain hotel
  • Hotel has a green policy Learn more
More Photos Exterior of Holiday Inn Ponce & Tropical Casino by IHG
From$170 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Four Points by Sheraton Caguas Real 500 Alhambra En Granada Blvd., Caguas, 00726 Puerto Rico
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~26.26 miles northeast of Santa Isabel
  • Affordable Suburban property
  • Hotel has 34 suites
More Photos Exterior of Four Points by Sheraton Caguas Real
From$130 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Four Points by Sheraton Caguas Real Hotel & Casino : 500 Alhambra En Granada Blvd. 500 Alhambra En Granada Blvd., Caguas, 00725 Puerto Rico
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~26.29 miles northeast of Santa Isabel
  • High end Suburban hotel
  • 7 meeting rooms in property
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From$150 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Hyatt Place Manati in Manati 122 Carretera Pr 2, Manati, 00674 Puerto Rico
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~31.72 miles north of Santa Isabel
  • 3 star Suburban property
  • 5 floors in property
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From$94 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Copamarina Beach Resort & Spa in Guanica Rd. 333 Km 6.5, Guanica, 00653 Puerto Rico
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~32.47 miles west of Santa Isabel
  • Expensive Oceanfront property
  • Hotel has 7 meeting rooms
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From$202 total
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Hyatt Place Bayamon Crta. 167 Avenida Ramon Luis Rivera, Bayamon, 00961 Puerto Rico
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~32.87 miles north of Santa Isabel
  • Affordable Downtown hotel
  • Hotel has an eco-friendly policy Read more
More Photos Image of Hyatt Place Bayamon
From$116 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
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San Miguel Plaza Hotel Calle Las Rosas 2, San Juan, 00961
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~33.22 miles north of Santa Isabel
  • 3 star property
  • 40 sleeping rooms in hotel
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From$108 total
Average 3.0 /5 Read Reviews Call BookMore Details
Parador Maunacaribe - Maunabo 901 Panoramic Rd. Km. 1.9, Maunabo, 00707 Puerto Rico
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~33.61 miles east of Santa Isabel
  • Three Star Beach hotel
More Photos Image of Parador Maunacaribe
From$226 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
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Dorado Beach a Ritz Carlton Reserve - Dorado 100 Dorado Beach Dr., Dorado, 00646 Puerto Rico
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~33.86 miles north of Santa Isabel
  • Luxurious 5 Star Resort property
  • Access to gym on-site
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From$720 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Coral by The Sea Hotel Calle Rosa 2, San Juan, 979 Puerto Rico
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~33.86 miles northeast of Santa Isabel
  • Low priced property
  • 5 floors in hotel
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From$72 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hyatt Vacation Club at Hacienda Del Mar Dorado - Dorado Vega Alta 301 Pr 693, Dorado Vega Alta, 00646 Puerto Rico
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~33.99 miles north of Santa Isabel
  • 4 star Resort property
  • Gym / Fitness Center Available
More Photos Image of Hyatt Vacation Club at Hacienda Del Mar Dorado
From$282 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Embassy Suites by Hilton Dorado Del Mar Beach Resort 201 Dorado Del Mar Blvd., Dorado, 00646 Puerto Rico
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~34.95 miles north of Santa Isabel
  • 3 star Beach hotel
  • 15 conference rooms in property
More Photos Image of Embassy Suites by Hilton Dorado Del Mar Beach Resort
From$109 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Howard Johnson Centro Cardiovascular San Juan : Americo Miranda Americo Miranda, San Juan, 00935 Puerto Rico
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~35.10 miles northeast of Santa Isabel
  • 3-star property
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From$96 total
Poor 2.0 /5 Read Reviews Call BookMore Details
Comfort Inn & Suites Levittown Del Valle Ave. 1829, Levittown, 00949 Puerto Rico Website
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~35.35 miles north of Santa Isabel
  • Midscale Oceanfront property
  • Comp. Breakfast
More Photos Image of Comfort Inn & Suites Levittown
From$80 total
Very Good 4.0 /5 Review Score Call BookMore Details
Courtyard by Marriott San Juan Miramar 801 Ponce De Leon Ave., San Juan, Puerto Rico
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~35.41 miles northeast of Santa Isabel
  • Affordable Downtown property
  • Hotel has 10 suites
More Photos Image of Courtyard by Marriott San Juan Miramar
From$116 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Parador Guánica 1929 Rd. 3116 Km 2.5 Los Veterano Ave., Guanica, 00647 Puerto Rico
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~35.56 miles west of Santa Isabel
  • Inexpensive Suburban property
  • 2 floors in hotel
More Photos Image of Parador Guánica 1929
From$122 total
Very Good 4.0 /5 Review Score Call BookMore Details
Parador Palmas De Lucía 901 Panoramic Rd. & 9911 Rd. Bo, Yabucoa, 00767 Puerto Rico
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~36.34 miles east of Santa Isabel
  • Low Cost Oceanfront hotel
  • Hotel has 3 floors
More Photos Image of Parador Palmas De Lucía
From$72 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hotel Plaza De Armas Old San Juan : San Jose St. 202 San Jose St. 202, San Juan, 00901 Puerto Rico
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~37.71 miles north of Santa Isabel
  • Inexpensive Downtown hotel
  • Check in: 3:00 PM
More Photos Image of Hotel Plaza De Armas Old San Juan
From$84 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Hotel El Convento 100 Cristo St., San Juan, 00901 Puerto Rico
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~37.74 miles north of Santa Isabel
  • Expensive Downtown property
  • Hotel has 5 meeting rooms
More Photos Photo of Hotel El Convento
From$163 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hotel Rumbao a Tribute Portfolio Hotel : 100 Brumbaugh St. 100 Brumbaugh St., San Juan, 00901 Puerto Rico
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~37.80 miles northeast of Santa Isabel
  • High-end Downtown hotel
  • 240 sleeping rooms in hotel
More Photos Image of Hotel Rumbao a Tribute Portfolio Hotel
From$118 total
Very Good 4.0 /5 Reviews Call BookMore Details
Hotel Milano in San Juan 307 Fortaleza St., San Juan, 901 Puerto Rico
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~37.83 miles northeast of Santa Isabel
  • 3 star hotel
  • Check-in time: 15:00
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From$108 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Aloft San Juan : 250 Convention Blvd. 250 Convention Blvd., San Juan, Puerto Rico
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~37.89 miles northeast of Santa Isabel
  • Three Star Downtown hotel
  • Check in: 4:00pm
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From$202 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Sheraton Puerto Rico Hotel & Casino 200 Convention Blvd., San Juan, 00907 Puerto Rico
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~37.93 miles northeast of Santa Isabel
  • Expensive Convention Center property
  • Hotel has 9 meeting rooms
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From$154 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Alma San Juan - San Juan 405 C. De San Francisco, San Juan, 00901 Puerto Rico
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~37.96 miles northeast of Santa Isabel
  • 4 star hotel
  • Hotel has 7 floors
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From$214 total
Average 3.0 /5 Reviews Call BookMore Details
Hotel Plaza De Armas Old San Juan 202 Calle San Jose, San Juan, 901
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~38.05 miles northeast of Santa Isabel
  • 3 star hotel
  • Check-in time: 15:00
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From$108 total
Average 3.0 /5 Read Reviews Call BookMore Details
Hyatt Place San Juan 580 Av. Manuel Fernández Juncos, San Juan, 00907 Puerto Rico
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~38.07 miles northeast of Santa Isabel
  • 3-star Convention Center property
  • Hotel has an eco-friendly policy Read more
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From$96 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hyatt House San Juan 615 Ave. Fernandez Juncos Distrito De Convenciones, San Juan, 00907 Puerto Rico
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~38.09 miles northeast of Santa Isabel
  • Affordable Convention Center hotel
  • Access to gym on-site
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From$156 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Vistas De San Juan #600 Ave. Fernandez Juncos Gc 14, San Juan Puerto Rico, Puerto Rico
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~38.14 miles northeast of Santa Isabel
  • Four-star Convention Center hotel
  • Gym / Fitness Center Available
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From$118 total
Average 3.0 /5 Read Reviews Call BookMore Details
Hotel Miramar - San Juan 606 Ponce De Leon Ave., San Juan, 00907 Puerto Rico
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~38.22 miles northeast of Santa Isabel
  • Three Star Beach hotel
  • Check in: 15:00
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From$108 total
Very Good 4.0 /5 Review Score Call BookMore Details
Juliette Hostel Sanjuan901.com, San Juan, 00901 Puerto Rico
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~38.22 miles northeast of Santa Isabel
  • Cheap Downtown property
  • 2 floors in property
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From$54 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Somos Hotel 1202 Av. Juan Ponce De León, San Juan, 00907 Puerto Rico
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~38.25 miles northeast of Santa Isabel
  • Affordable Downtown property
  • 2 floors in hotel
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From$60 total
Average 3.0 /5 Recent Reviews Call BookMore Details
The Wave Hotel Condado : 76 Condado Ave. 76 Condado Ave., San Juan, 00907 Puerto Rico
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~38.47 miles northeast of Santa Isabel
  • Midscale Downtown property
  • 47 rooms in hotel
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From$108 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
El San Geronimo Hotel 54 Av. Luis Muñoz Rivera, San Juan, 00901 Puerto Rico
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~38.54 miles northeast of Santa Isabel
  • Mid-scale Downtown property
  • 28 rooms in property
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From$96 total
Average 3.0 /5 Read Reviews Call BookMore Details
Hotel Mome - San Juan #54 Luis Muñoz Rivera, San Juan, 00901 Puerto Rico
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~38.54 miles northeast of Santa Isabel
  • Mid-scale Downtown property
  • 28 rooms in property
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From$202 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Casa Del Caribe Inn in Condado, 57 Caribe St. Condado, Condado,, 00907 Puerto Rico
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~38.56 miles northeast of Santa Isabel
  • Inexpensive property
  • Check in: 14:00
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From$72 total
Average 3.5 /5 Hotel Reviews Call BookMore Details
Abitta Boutique Hotel, Ascend Hotel Collection Clemenceau St. #6 Condado, San Juan, 00907 Puerto Rico
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~38.57 miles northeast of Santa Isabel
  • Mid-scale Downtown property
  • 7 floors in hotel
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From$96 total
Average 3.5 /5 Hotel Reviews Call BookMore Details
Ciqala Suites Hotel 752 Av. Manuel Fernandez Juncos, San Juan, 00915 Puerto Rico
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~38.57 miles northeast of Santa Isabel
  • 3 star property
  • Check-in: 16:00
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From$108 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
The Ivy Hotel San Juan 1149 Magdalena Ave. Condado, San Juan, 00907 Puerto Rico
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~38.58 miles northeast of Santa Isabel
  • Three Star property
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From$96 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Coral Princess Hotel : 1159 Avenida Magdalena 1159 Avenida Magdalena, San Juan, 00907 Puerto Rico
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~38.58 miles northeast of Santa Isabel
  • Affordable Suburban hotel
  • 3 floors in property
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From$114 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express San Juan Condado by IHG : 1 Mariano Ramirez Bages St. 1 Mariano Ramirez Bages St., San Juan, 00907 Puerto Rico
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~38.59 miles northeast of Santa Isabel
  • 3 star Beach property
  • 116 sleeping rooms in hotel
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From$106 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Olive Boutique Hotel, A Small Luxury Hotel of the World (Adults O Aguadilla St. #55 Condado, San Juan, 00907 Puerto Rico
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~38.62 miles northeast of Santa Isabel
  • Luxurious 5 Star Downtown property
  • 7 suites in property
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From$166 total
Very Good 4.0 /5 Review Score Call BookMore Details
Caribe Hilton : 1 San Geronimo St. 1 San Geronimo St., San Juan, 00901 Puerto Rico
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~38.62 miles northeast of Santa Isabel
  • Four-star Beach property
  • Hotel has 39 suites
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From$138 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
OLV Fifty Five - Adults Only - San Juan 55 Barranquitas St., San Juan, 00907
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~38.62 miles northeast of Santa Isabel
  • 3 star hotel
  • 22 rooms in hotel
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From$108 total
Very Good 4.0 /5 Reviews Call BookMore Details

Next: See My Santa Isabel Hotels with Pricing

Bar Chart: Upcoming 20 Days of Santa Isabel Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Santa Isabel, Puerto Rico discounts available. The chart reflects the cheapest Santa Isabel hotel for each day and each star rating category.

FAQs about hotels in Santa Isabel

What are the top rated hotels in Santa Isabel?

Copamarina Beach Resort & Spa, Caribe Hotel Ponce and Spark by Hilton Ponce are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels in Santa Isabel?

Dorado Beach a Ritz Carlton Reserve, Olive Boutique Hotel, A Small Luxury Hotel of the World (Adults O and Hilton Ponce Golf & Casino Resort are the top 3 luxury hotels near Santa Isabel city center.

What hotels are closest to the city center of Santa Isabel?

Marina de Salinas, Caribe Hotel Ponce, and Spark by Hilton Ponce are the properties closest to Santa Isabel city center.

What are the most popular independent hotels in Santa Isabel?

Copamarina Beach Resort & Spa, Caribe Hotel Ponce and Ponce Plaza Hotel & Casino are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Santa Isabel?

Dorado Beach a Ritz Carlton Reserve, Courtyard by Marriott San Juan Miramar and Hotel Rumbao a Tribute Portfolio Hotel are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels in Santa Isabel?

Comfort Inn & Suites Levittown and Abitta Boutique Hotel, Ascend Hotel Collection are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels in Santa Isabel?

Holiday Inn Ponce & Tropical Casino by IHG and Holiday Inn Express San Juan Condado by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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