Chillicothe Missouri Accommodations

Only hotels in Chillicothe are listed below. Find discounted hotel accommodations in or close to Chillicothe, MO for your upcoming individual or group travel. We provide the best Chillicothe Missouri hotel/motel rooms. Review the Chillicothe hotel list below to find the perfect lodging. We also have a map of the Chillicothe hotels. Group booking? Search Chillicothe Group Hotel Discounts

Chillicothe is a lovely city located in north-central Missouri. The name "Chillicothe" is Shawnee for "big town" and comes from an old Shawnee Indian town in the vicinity. Incorporated in 1851, it is home to a number of historic buildings and sites. There are many beautiful Victorian-style homes, as well as a wide range of shops and restaurants around. It is also an amazing location for nature lovers, with many green spaces and trails to explore. Chillicothe is a terrific place to visit if you are interested in learning about Missouri's history or if you just want to enjoy a charming small town. Local hotels offer a comfortable resting place whether you are traveling for business or pleasure. More from this guide...

Chillicothe Hotels, Motels & Accommodations

Quality Inn Cameron 1803 Comfort Ln, Cameron, MO 64429 +1-888-389-4121 ~35.60 miles west of Chillicothe
  • Affordable hotel
  • Check-in time: 3:00 PM - 6:00 AM
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Very Good 8.4 /10 Review Score Call BookMore Details
Red Roof Inn Cameron 501 Northland Drive, Cameron, MO 64429 +1-888-675-2083 ~36.44 miles west of Chillicothe
  • Cheap hotel
  • 3 floors in property
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Very Good 8.6 /10 Latest Reviews Call BookMore Details
Quality Inn & Suites Bethany 496 South 39th Street, Bethany, MO 64424 +1-800-716-8490 ~40.72 miles northwest of Chillicothe
  • Mid-scale hotel
  • 3 floors in hotel
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Average 7.6 /10 Recent Reviews Call BookMore Details
Super 8 by Wyndham Bethany MO 811 South 37th St, Bethany, MO 64424 +1-800-805-5223 ~40.70 miles northwest of Chillicothe
  • Two-star hotel
  • Check in: 2:00 PM - anytime
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Very Good 8.0 /10 Read Reviews Call BookMore Details
Super 8 by Wyndham Cameron 1710 North Walnut St, Cameron, MO 64429 +1-888-965-1860 ~36.51 miles west of Chillicothe
  • Economical property
  • Hotel has 2 floors
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Very Good 8.4 /10 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites Chillicothe 220 West Business 36, Chillicothe, MO 64601 +1-888-788-5576
  • Midscale hotel
  • 78 sleeping rooms in hotel
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Excellent 9.6 /10 Recent Reviews Call BookMore Details
SureStay Hotel by Best Western Cameron 2210 US Highway 36, Cameron, MO 64429 +1-888-897-9207 ~35.84 miles west of Chillicothe
  • 3 star property
  • Pets Welcome
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Very Good 8.0 /10 Recent Reviews Call BookMore Details
Days Inn by Wyndham Cameron 601 East Bryan Road, Cameron, MO 64429 +1-888-311-4278 ~36.41 miles west of Chillicothe
  • Two star property
  • Hotel has 2 floors
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Average 7.6 /10 Latest Reviews Call BookMore Details
Motel 6 Cameron MO 1920 North Bob Griffin Road, Cameron, MO 64429 +1-888-469-4795 ~35.40 miles west of Chillicothe
  • 2 star Motel hotel
  • Hotel has 44 rooms
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Average 7.0 /10 Review Score Call BookMore Details
Best Western Brookfield 28622 Highway 11, Brookfield, MO 64628 +1-888-734-9421 ~25.42 miles east of Chillicothe
  • 3 star hotel
  • 31 rooms in property
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Excellent 9.0 /10 Review Score Call BookMore Details
Super 8 by Wyndham Richmond 888 Slumber Lane, Richmond, MO 64085 +1-888-841-5292 ~42.65 miles southwest of Chillicothe
  • 2 star Motel property
  • Pets are Welcome
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Very Good 8.6 /10 Hotel Reviews Call BookMore Details
Hotel Marceline 101 West Ira Street, Marceline, MO 64658 +1-888-455-5160 ~32.72 miles east of Chillicothe
  • Affordable property
  • Check in time: 12:00 PM - anytime
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Very Good 8.6 /10 Latest Reviews Call BookMore Details
Cobblestone Inn & Suites - Trenton 2900 Hoover Drive, Trenton, MO 64683 +1-888-965-8297 ~20.51 miles north of Chillicothe
  • Affordable property
  • Gym is available on property
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Excellent 9.0 /10 Review Score Call BookMore Details
Jamesport Inn 305 West Auberry Grove, Jamesport, MO 64648 +1-888-906-6358 ~18.24 miles northwest of Chillicothe
  • Economical Motel hotel
  • 15 rooms in property
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Very Good 8.0 /10 Guest Reviews Call BookMore Details
Family Budget Inn Bethany 4014 Miller St, Bethany, MO 64424 +1-888-749-6785 ~40.45 miles northwest of Chillicothe
  • Low-priced hotel
  • Pet-friendly
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Very Good 8.0 /10 Latest Reviews Call BookMore Details
Econo Lodge Cameron 220 East Grand Ave, Cameron, MO 64429 +1-888-878-9982 ~36.61 miles west of Chillicothe
  • Cheap hotel
  • Check in time: 2:00 PM - 5:00 AM
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Average 6.0 /10 Review Score Call BookMore Details
Westbridge Inn & Suites Carrollton 1408 Highway 65 N, Carrollton, MO 64633 +1-888-389-4485 ~29.21 miles south of Chillicothe
  • Two star Motel hotel
  • Free breakfast available
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Average 7.8 /10 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Chillicothe 580 Business Old Highway 36 E, Chillicothe, MO 64601 +1-888-389-4121
  • Two star Motel hotel
  • 2 suites in property
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Average 6.6 /10 Hotel Reviews Call BookMore Details
Motel 6 – Chillicothe MO 1020 South Washington St, Chillicothe, MO 64601 +1-888-675-2083
  • Affordable Motel property
  • Hotel has 57 rooms
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Average 6.2 /10 Recent Reviews Call BookMore Details
Comfort Inn & Suites Chillicothe 250 Business 36, Chillicothe, MO 64601 +1-800-716-8490
  • Mid-scale hotel
  • Has environment-friendly policy See policy
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Very Good 8.7 /10 Read Reviews Call BookMore Details
Martin House Motel 731 South Main St, Brookfield, MO 64628 +1-800-805-5223 ~25.72 miles east of Chillicothe
  • Two star Motel property
  • Check in time: 2:00 PM - 9:30 PM
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Average 7.2 /10 Hotel Reviews Call BookMore Details
Super 8 Carrollton 1408 US 65 MO, Carrollton, Missouri 64633 +1-888-965-1860 ~29.26 miles south of Chillicothe
  • Low-priced property
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La Bella Motel 110 North Mason St. CarrolltonMissouri 64633, Carrollton, 64633 +1-888-788-5576 ~30.30 miles south of Chillicothe
  • Low Cost Motel hotel
  • Check in time: 14:00:00
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Lakeview Inn & Cafe 3307 East 10th St. Highway 6 EastTrentonMissouri 64683, Trenton, 64683 +1-888-897-9207 ~19.40 miles north of Chillicothe
  • Cheap hotel
  • Check-in: 16:00:00
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The Best Time to Visit Chillicothe, MO

There is no definitive answer as to when to visit Chillicothe, MO as different people have different preferences, but in general, the best time to visit Chillicothe, MO is in the spring or fall. The weather is usually milder during these seasons, and the scenery is beautiful. If you like outdoor activities, these are ideal periods to come, as there are plenty of hiking and biking trails in the area. The town comes alive and there is always something to do. From festivals to farmers' markets, there is always something going on. If you happened to visit in the summer months, you might want to check out Chilli Bay Water Park. It is a wonderful place to cool off in the summer heat as the temperatures rise to 88 °F. The park has a lazy river, two slides, and a splash pad. An amazing place to relax and float around. And during the winter the snow-covered streets and festive decorations make Chillicothe truly magical as temperatures drop to 17 °F. There are a variety of activities to keep you busy during your stay, from ice skating and sledding to shopping and dining. Whatever time you'll come, you're sure to find something to love about Chillicothe.

Hotel Discounts in Chillicothe, Missouri

Whether you're searching for a hotel, motel, or bed and breakfast, there's a good deal for you in Chillicothe. Local hotels have a variety of discounts for their guests, including discounts for AAA members and seniors, for government employees, and for active military members and their families. There's also a wide range of package deals that include discounts on meals, attractions, and more. Doesn't matter if you're looking for a weekend getaway or an extended stay, there's the perfect room for you at the best price. So check out the local discounts and choose the one that is just right for you. Hotel discounts are available throughout the year, depending on the season. During the winter months, discounts are often available for guests who are willing to bundle up and brave the cold weather. Spring and summer are peak tourist season in Chillicothe, so discounts are typically not available during these times. However, if you're willing to travel during the off-season, you can often find great deals on hotel rooms.

Chillicothe, MO: Sights to See 

There is plenty to do in the historic town of Chillicothe, Missouri. Visit the Grand River Historical Society. It operates a museum that is open to the public and houses a collection of artifacts and documents related to the history of the region. The Society sponsors different educational programs and events throughout the year. You also wouldn't want to miss the Chillicothe Industrial Home for Girls, a national historic district with 10 buildings, 1 site, and 7 structures that used to be an industrial home. The home is an amazing example of Colonial Revival and Streamline Moderne-style architecture. For a wonderful day out, go to the nearby Thompson River, a popular spot for fishing, kayaking, and canoeing. There are a number of scenic hiking and biking trails as well. Finally, check out Simpson Park, one of the city's oldest landmarks and best-known recreation facilities. It has the ambiance of a beautiful, old-style park with trees dating back 200 years. Whether you are planning to explore the city's history or enjoy the outdoors, Chillicothe has something for everyone. The Grand River Historical Society in Chillicothe, Missouri is a great place to learn about the history of the area and to see some amazing historical artifacts. The society has a museum with a wide variety of artifacts on display, as well as a library with a wealth of information about the area. The staff is very knowledgeable and passionate about the history of the area, and they are always happy to answer any questions you may have. The society also offers a variety of events and programs throughout the year, which are always enjoyable and educational. If you are looking for a great place to learn about the history of the area, the Grand River Historical Society is definitely worth a visit.

What did travelers think of the city of Chillicothe?

Below are reviews of the city of Chillicothe, MO from an actual visitor's perspective.

" I love this little town"
Score 4.0 / 5

I was born and raised here! I love this little town.

Brian D., from 27-Aug-2026
"Downtown was very nice"
Score 5.0 / 5

Dirk N., from 09-Dec-2025
"Restaurants close by"
Score 4.0 / 5

A couple restaurants we close by, within walking distance.

Sandra J., from 25-Oct-2025
"Applebee's"
Score 5.0 / 5

We also loved that there was an Applebee's right next door. Real food. Not fast food.

Jacoba W., from 18-Oct-2025
"City"
Score 5.0 / 5

Most of all, we like that it is the city of origin for our family. And we thoroughly enjoy the Downtown murals.

Christie B., from 05-Oct-2025
"Great Stay!"
Score 4.0 / 5

Homey!

Mervin H., from 24-Jun-2025
"Always Enjoyable"
Score 5.0 / 5

We always enjoy coming. Black Water was excellent and the staff at Applebees was very good!

Sharon G., from 10-May-2025
"Friendly"
Score 5.0 / 5

Friendly people

Joyce K., from 30-Mar-2025
"Enjoyable Place"
Score 5.0 / 5

Nice clean town; we enjoyed ourselves. Thank you

Joyce K., from 29-Mar-2025
"Nice Clean Town!"
Score 4.0 / 5

Nice clean town.

Joyce K., from 29-Mar-2025
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