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Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels/Accommodations

Super 8 by Wyndham Greenville - Greenville 1700 State Route 127, Greenville, IL 62246
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  • Economy Rural property
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From$60
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SureStay by Best Western Greenville - Greenville 1731 South State Route 127, Greenville, IL 62246
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  • Inexpensive Highway hotel
  • Hotel has 77 rooms
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From$42
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Comfort Inn & Suites Greenville I-70 2265 South State Route 127, Greenville, IL 62246 Website
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  • Low-priced Rural hotel
  • Hotel has 2 meeting rooms
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From$53
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Holiday Inn Express & Suites Vandalia Il : 21 Mattes Ave. 21 Mattes Ave., Vandalia, IL 62471
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~15.52 miles east of Greenville
  • Midscale Highway hotel
  • Fitness / Gym is on-site
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From$80
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Ramada by Wyndham Vandalia : 2707 Veterans Ave. 2707 Veterans Ave., Vandalia, IL 62471
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~15.77 miles east of Greenville
  • Low Cost property
  • Check in: 11:00 AM
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From$60
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Americas Best Value Inn Vandalia : 1500 North 6th St. 1500 North 6th St., Vandalia, IL 62471
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~17.45 miles east of Greenville
  • Economy Lake hotel
  • Hotel has 44 rooms
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From$50
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Quality Inn & Suites Vandalia near I-70 and Hwy 51 : 1920 North Kennedy Blvd. 1920 North Kennedy Blvd., Vandalia, IL 62471 Website
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~17.57 miles east of Greenville
  • Economy Highway property
  • Free breakfast available
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From$60
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Quality Inn & Suites Vandalia near I-70 and Hwy 51 1920 Kennedy Blvd., Vandalia, IL 62471
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~17.59 miles east of Greenville
  • Cheap Rural hotel
  • 85 sleeping rooms in hotel
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From$57
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Seasons Inn & Suites Highland in Highland 20 Central Blvd., Highland, IL 62249
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~17.74 miles southwest of Greenville
  • Two star property
  • Free breakfast
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From$65
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Mariner's Village Resort & Inn 1 Resort Dr., Carlyle, IL 62231
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~18.34 miles south of Greenville
  • Economical Lake property
  • Complimentary breakfast is offered
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From$59
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Centerstone Inn & Suites : 1371 William Rd. 1371 William Rd., Carlyle, IL 62231
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~18.46 miles south of Greenville
  • Two star hotel
  • Hotel has 41 rooms
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From$60
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Super 8 by Wyndham Staunton : 1527 Herman Rd. 1527 Herman Rd., Staunton, IL 62088
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~21.09 miles west of Greenville
  • Cheap property
  • 50 sleeping rooms in hotel
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From$50
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Innkeeper Motel in Hamel 401 East State St., Hamel, IL 62046
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~23.07 miles west of Greenville
  • 3 star Lake hotel
  • Hotel has 2 floors
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From$80
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Americas Best Value Inn Litchfield 224 North Ohren Lane, Litchfield, IL 62056
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~24.10 miles northwest of Greenville
  • Inexpensive property
  • Hotel has 2 floors
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From$60
Poor 2.0 /5 Review Score Call BookMore Details
Motel 6 Litchfield, IL in Litchfield 211 Ohren Ln, Litchfield, IL 62056
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~24.16 miles northwest of Greenville
  • Cheap Highway property
  • Check in time: 11:00 AM
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From$60
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Baymont by Wyndham Litchfield 1405 West Hudson Dr., Litchfield, IL 62056
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~24.16 miles northwest of Greenville
  • Inexpensive Highway property
  • 3 floors in property
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From$60
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Quality Inn Litchfield Route 66 in Litchfield 1010 East Columbian Blvd. North, Litchfield, IL 62056 Website
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~24.37 miles northwest of Greenville
  • Two-star Downtown property
  • Fitness + Health Center
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From$70
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Hampton Inn Litchfield 11 Thunderbird Cir, Litchfield, IL 62056
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~24.48 miles northwest of Greenville
  • Three Star Highway property
  • Gym is available on property
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From$80
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Holiday Inn Express & Suites Litchfield West by IHG - Litchfield 4 Thunderbird Circle, Litchfield, IL 62056
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~24.49 miles northwest of Greenville
  • Affordable Rural hotel
  • Hotel has 4 floors
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From$79
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Best Western Plus Centralia Hotel & Suites : 8145 Jolliff Bridge Rd. 8145 Jolliff Bridge Rd., Centralia, IL 62801
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~28.09 miles southeast of Greenville
  • 3 star property
  • 3 meeting rooms in property
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From$78
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Americas Best Value Inn : 200 East Noleman 200 East Noleman, Centralia, IL 62801
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~29.09 miles southeast of Greenville
  • Economical property
  • 57 rooms in property
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From$60
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Motel 6 Troy Il - Troy 909 Edwardsville Rd., Troy, IL 62294
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~29.31 miles west of Greenville
  • Low-priced hotel
  • Check in time: 15:00
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From$50
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Quality Inn & Suites Salem near I-57 in Salem 1800 West Main St., Salem, IL 62881 Website
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~29.38 miles southeast of Greenville
  • Two star Rural property
  • 65 rooms in property
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From$69
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Best Western Troy Hotel in Troy 2020 Formosa Rd., Troy, IL 62294
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~29.44 miles west of Greenville
  • 3 star Rural hotel
  • 65 rooms in hotel
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From$60
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Holiday Inn Express Troy by IHG in Troy 2011 Formosa Rd., Troy, IL 62294
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~29.51 miles west of Greenville
  • 3 star Highway property
  • Gym / Fitness Center Available
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From$84
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Red Roof Inn St Louis - Troy, IL 2030 Formosa Rd., Troy, IL 62294
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~29.55 miles west of Greenville
  • Economical property
  • 3 floors in hotel
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From$53
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Days Inn by Wyndham Salem, Illinois : 1812 West Main St. 1812 West Main St., Salem, IL 62881
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~29.55 miles southeast of Greenville
  • Economy property
  • 2 floors in hotel
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From$47
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Super 8 by Wyndham Troy IL/St. Louis Area - Troy 910 Edwardsville Rd., Troy, IL 62294
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~29.60 miles west of Greenville
  • Inexpensive Highway hotel
  • Check-in time: 03:00 PM
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From$63
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Super 8 by Wyndham Salem 118 Woods Ln, Salem, IL 62881
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~29.63 miles southeast of Greenville
  • Economy Highway hotel
  • Hotel has 58 rooms
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From$60
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Magnuson Grand Hotel And Conference Center 19067 West Frontage Rd., Raymond, IL 62560
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~29.70 miles northwest of Greenville
  • 3-star Rural hotel
  • Gym is available on property
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From$49
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Salem by IHG 102 Holiday Lane, Salem, IL 62881
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~29.89 miles southeast of Greenville
  • 3 star Highway hotel
  • Hotel has a green policy See policy
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From$87
Excellent 5.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Edwardsville by IHG in Edwardsville 1000 Plummer Dr., Edwardsville, IL 62025
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~31.59 miles west of Greenville
  • 3-star Suburban property
  • Free comp. breakfast
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From$94
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Country Hearth Inn & Suites Edwardsville St. Louis 1013 Plummer Dr., Edwardsville, IL 62025
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~31.66 miles west of Greenville
  • 3-star Rural property
  • 3 floors in hotel
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From$67
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Towneplace Suites by Marriott St. Louis Edwardsville Il 6101 Center Grove Rd., Edwardsville, IL 62025
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~31.67 miles west of Greenville
  • 3-star Suburban property
  • Hotel has 91 rooms
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From$90
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Best Western Plus MidAmerica Hotel - Mascoutah 9730 Hayden Dr., Mascoutah, IL 62258
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~32.05 miles southwest of Greenville
  • 3-star Suburban property
  • Has environment-friendly policy Read more
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From$69
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Super 8 by Wyndham Okawville 812 North Henhouse Rd., Okawville, IL 62271
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~32.28 miles south of Greenville
  • Cheap Rural hotel
  • 2 floors in hotel
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From$64
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Okawville in Okawville 812 North Hen House Rd., Okawville, IL 62271
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~32.28 miles south of Greenville
  • Economical property
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From$60
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Super 8 by Wyndham O'fallon : 1100 Eastgate Dr. 1100 Eastgate Dr., Ofallon, IL 62269
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~33.41 miles southwest of Greenville
  • Low priced Suburban property
  • 2 floors in hotel
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From$40
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Comfort Inn Edwardsville - St. Louis : 3080 South State Rte 157 3080 South State Rte 157, Edwardsville, IL 62025 Website
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~33.44 miles west of Greenville
  • 2 star Highway property
  • Hotel has 4 suites
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From$60
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Comfort Inn Edwardsville 3080 Il 157, Edwardsville, IL 62025
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~33.44 miles west of Greenville
  • Midscale Highway hotel
  • 74 rooms in hotel
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From$80
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Hampton Inn & Suites St. Louis Edwardsville 5723 Heritage Crossing Dr., Glen Carbon, IL 62034
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~33.74 miles west of Greenville
  • 3 star Suburban property
  • Comp. Breakfast
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From$99
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Best Western U. S. Inn 11640 State Route 127, Nashville, IL 62263
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~35.22 miles south of Greenville
  • Affordable Highway property
  • Comp. Breakfast
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From$64
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Sleep Inn O Fallon Il 140 Venita Dr., O'fallon, IL 62269
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~35.35 miles southwest of Greenville
  • 3 star Suburban hotel
  • 71 sleeping rooms in hotel
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From$80
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Holiday Inn Express & Suites O'fallon / Shiloh An Ihg Hotel - Shiloh 3396 Green Mount Crossing, Shiloh, IL 62269
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~35.48 miles southwest of Greenville
  • Affordable Highway property
  • Free comp. breakfast
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From$99
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Comfort Inn & Suites Ofallon St. Louis Area - O'fallon 116 Regency Park, O'fallon, IL 62269
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~35.51 miles southwest of Greenville
  • 2 star Suburban property
  • 66 sleeping rooms in hotel
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From$60
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Hampton Inn O'fallon Il - O'fallon 430 Regency Park, O'fallon, IL 62269
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~35.57 miles southwest of Greenville
  • Mid-scale Suburban property
  • Hotel has 100 rooms
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From$80
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La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis - O'fallon 136 Regency Park, O'fallon, IL 62269
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~35.59 miles southwest of Greenville
  • Inexpensive Suburban hotel
  • Hotel has 2 floors
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From$60
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Hilton Garden Inn St. Louis Shiloh / O'fallon Il in O'fallon 360 Regency Park, O'fallon, IL 62269
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~35.65 miles southwest of Greenville
  • Mid-scale Suburban property
  • Fitness / Gym is on-site
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From$80
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Extended Stay America Select Suites - St. Louis - O' Fallon, IL 154 Regency Park, O'fallon, IL 62269
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~35.68 miles southwest of Greenville
  • Cheap Highway hotel
  • 89 rooms in property
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From$39
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Drury Inn St. Louis Collinsville 602 North Bluff Rd., Collinsville, IL 62234
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~35.68 miles west of Greenville
  • 3-star Suburban property
  • Hotel has an eco-friendly policy See more
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From$90
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Next: See My Greenville Hotels with Pricing

Graph: Upcoming 20 Days of Greenville Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Greenville, IL discounts available. The chart reflects the cheapest Greenville hotel for each day and each star rating category.

FAQs about hotels in Greenville

What are the top reviewed hotels in Greenville?

Holiday Inn Express & Suites Salem by IHG, Quality Inn & Suites Vandalia near I-70 and Hwy 51 and Quality Inn Litchfield Route 66 are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Greenville?

Holiday Inn Express & Suites Vandalia Il, Innkeeper Motel and Hampton Inn Litchfield are the top 3 luxury hotels near Greenville city center.

What hotels are closest to the city center of Greenville?

Super 8 by Wyndham Greenville, SureStay by Best Western Greenville, and Comfort Inn & Suites Greenville I-70 are the properties closest to Greenville city center.

What are the best independent hotels in Greenville?

Mariner's Village Resort & Inn, Magnuson Grand Hotel And Conference Center and Centerstone Inn & Suites are the best rated independent hotels (not part of a big brand).

What are the most popular Choice Hotels branded hotels in Greenville?

Quality Inn & Suites Vandalia near I-70 and Hwy 51, Quality Inn Litchfield Route 66 and Comfort Inn & Suites Greenville I-70 are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular Best Western hotels in Greenville?

Best Western Plus Centralia Hotel & Suites, Best Western Plus MidAmerica Hotel and Best Western U. S. Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the most popular IHG hotels in Greenville?

Holiday Inn Express & Suites Salem by IHG, Holiday Inn Express Troy by IHG and Holiday Inn Express & Suites Litchfield West by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Quiet town"
Score 4.0 / 5

Quiet town and my Son plays Basketball for Greenville university.

Newton A., from 26-Feb-2026
"Great Diner!"
Score 4.0 / 5

Vicky's Cafe was awesome!! Very helpful and polite staff! Clean diner with great food!

Amy S., from 24-Aug-2025
"Dressed up Strip area."
Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025
"Quiet Area"
Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024
"Proximity to Carlyle"
Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024
"Greenville has some excellent museums!"
Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023
"Great Aquarium"
Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023
"College Campus"
Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023
"Loved It!"
Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022
The average traveler rating of the city of Greenville, IL shown above is 4.3 out of 5 based on 9 reviews
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