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Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels/Motels & Accommodations

Super 8 by Wyndham Greenville - Greenville
+1-888-389-4121
1700 State Route 127, Greenville, IL 62246
  • Inexpensive Rural hotel
  • Check in time: 12:00 PM
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
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SureStay by Best Western Greenville : 1731 South State Route 127
+1-888-675-2083
1731 South State Route 127, Greenville, IL 62246
  • Two-star Highway hotel
  • Free complimentary breakfast
From$42
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Inn & Suites Greenville I-70 - Greenville
+1-800-716-8490
2265 South State Route 127, Greenville, IL 62246 Website
  • Low priced Rural property
  • 2 meeting rooms in hotel
From$53
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Vandalia Il : 21 Mattes Ave.
+1-800-805-5223
21 Mattes Ave., Vandalia, IL 62471 ~15.52 miles east of Greenville
  • Midscale Highway property
  • Check in time: 3:00 PM
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Ramada by Wyndham Vandalia
+1-888-965-1860
2707 Veterans Ave., Vandalia, IL 62471 ~15.77 miles east of Greenville
  • Cheap property
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn Vandalia
+1-888-788-5576
1500 North 6th St., Vandalia, IL 62471 ~17.45 miles east of Greenville
  • Two-star Lake property
  • 2 floors in hotel
From$50
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 : 1920 North Kennedy Blvd.
+1-888-897-9207
1920 North Kennedy Blvd., Vandalia, IL 62471 Website ~17.57 miles east of Greenville
  • Two-star Highway hotel
  • Free breakfast available
From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51
+1-888-311-4278
1920 Kennedy Blvd., Vandalia, IL 62471 ~17.59 miles east of Greenville
  • 2-star Rural property
  • Check-in time: 2:00 p.m.
From$57
Very Good 4.5 /5 Read Reviews Call BookMore Details
Seasons Inn & Suites Highland
+1-888-469-4795
20 Central Blvd., Highland, IL 62249 ~17.74 miles southwest of Greenville
  • 2-star hotel
  • Free breakfast available
From$65
Average 3.0 /5 Guest Reviews Call BookMore Details
Mariner's Village Resort & Inn in Carlyle
+1-888-734-9421
1 Resort Dr., Carlyle, IL 62231 ~18.34 miles south of Greenville
  • Low-priced Lake hotel
  • Comp. Breakfast
From$59
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Centerstone Inn & Suites : 1371 William Rd.
+1-888-841-5292
1371 William Rd., Carlyle, IL 62231 ~18.46 miles south of Greenville
  • 2 star hotel
  • Check in time: 3:00 PM
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Staunton
+1-888-455-5160
1527 Herman Rd., Staunton, IL 62088 ~21.09 miles west of Greenville
  • 2 star hotel
  • Hotel has an eco-friendly policy Learn more
From$50
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Innkeeper Motel
+1-888-965-8297
401 East State St., Hamel, IL 62046 ~23.07 miles west of Greenville
  • Affordable Lake property
  • Check-in time: 2:00 PM
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Americas Best Value Inn Litchfield : 224 North Ohren Lane
+1-888-906-6358
224 North Ohren Lane, Litchfield, IL 62056 ~24.10 miles northwest of Greenville
  • Two-star hotel
  • Free breakfast available
Motel 6 Litchfield, IL - Litchfield
+1-888-749-6785
211 Ohren Ln, Litchfield, IL 62056 ~24.16 miles northwest of Greenville
  • Cheap Highway property
  • Check in: 11:00 AM
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
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Baymont by Wyndham Litchfield - Litchfield
+1-888-878-9982
1405 West Hudson Dr., Litchfield, IL 62056 ~24.16 miles northwest of Greenville
  • Low-priced Highway property
  • 5 suites in property
From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Inn Litchfield Route 66 : 1010 East Columbian Blvd. North
+1-888-389-4485
1010 East Columbian Blvd. North, Litchfield, IL 62056 Website ~24.37 miles northwest of Greenville
  • 2 star Downtown property
  • Check in time: 3:00 PM
From$70
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Hampton Inn Litchfield : 11 Thunderbird Cir
+1-888-389-4121
11 Thunderbird Cir, Litchfield, IL 62056 ~24.48 miles northwest of Greenville
  • Midscale Highway hotel
  • Check in time: 3:00pm
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Litchfield West by IHG : 4 Thunderbird Circle
+1-888-675-2083
4 Thunderbird Circle, Litchfield, IL 62056 ~24.49 miles northwest of Greenville
  • 3 star Rural hotel
  • Fitness center on property
From$79
Very Good 4.0 /5 Read Reviews Call BookMore Details
Best Western Plus Centralia Hotel & Suites
+1-800-716-8490
8145 Jolliff Bridge Rd., Centralia, IL 62801 ~28.09 miles southeast of Greenville
  • Three Star hotel
  • 17 suites in hotel
From$78
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Americas Best Value Inn
+1-800-805-5223
200 East Noleman, Centralia, IL 62801 ~29.09 miles southeast of Greenville
  • Cheap hotel
  • Free breakfast
From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Motel 6 Troy Il in Troy
+1-888-965-1860
909 Edwardsville Rd., Troy, IL 62294 ~29.31 miles west of Greenville
  • Economical hotel
  • Check-in time: 15:00
From$50
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites Salem near I-57 in Salem
+1-888-788-5576
1800 West Main St., Salem, IL 62881 Website ~29.38 miles southeast of Greenville
  • 2 star Rural hotel
  • 20 suites in property
From$69
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Best Western Troy Hotel
+1-888-897-9207
2020 Formosa Rd., Troy, IL 62294 ~29.44 miles west of Greenville
  • Midscale Rural hotel
  • Hotel has 10 suites
From$60
Average 3.5 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Troy by IHG : 2011 Formosa Rd.
+1-888-311-4278
2011 Formosa Rd., Troy, IL 62294 ~29.51 miles west of Greenville
  • 3-star Highway hotel
  • 4 floors in hotel
From$84
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Red Roof Inn St Louis - Troy, IL
+1-888-469-4795
2030 Formosa Rd., Troy, IL 62294 ~29.55 miles west of Greenville
  • Low-priced property
  • 8 suites in hotel
From$53
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Salem, Illinois : 1812 West Main St.
+1-888-734-9421
1812 West Main St., Salem, IL 62881 ~29.55 miles southeast of Greenville
  • Low Cost hotel
  • Gym / Fitness Center Available
From$47
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Troy IL/St. Louis Area : 910 Edwardsville Rd.
+1-888-841-5292
910 Edwardsville Rd., Troy, IL 62294 ~29.60 miles west of Greenville
  • Low priced Highway hotel
  • 61 rooms in property
From$63
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Salem
+1-888-455-5160
118 Woods Ln, Salem, IL 62881 ~29.63 miles southeast of Greenville
  • Low Cost Highway property
  • 3 floors in property
From$60
Average 3.0 /5 Review Score Call BookMore Details
Magnuson Grand Hotel And Conference Center in Raymond
+1-888-965-8297
19067 West Frontage Rd., Raymond, IL 62560 ~29.70 miles northwest of Greenville
  • Three Star Rural property
  • 97 sleeping rooms in hotel
From$49
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Salem by Ihg - Salem
+1-888-906-6358
102 Holiday Lane, Salem, IL 62881 ~29.89 miles southeast of Greenville
  • Three Star Highway property
  • Access to gym on-site
From$87
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Edwardsville by IHG
+1-888-749-6785
1000 Plummer Dr., Edwardsville, IL 62025 ~31.59 miles west of Greenville
  • Affordable Suburban property
  • Access to gym on-site
From$94
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Country Hearth Inn & Suites Edwardsville St. Louis
+1-888-878-9982
1013 Plummer Dr., Edwardsville, IL 62025 ~31.66 miles west of Greenville
  • 3 star Rural property
  • Hotel has 3 floors
From$67
Very Good 4.0 /5 Latest Reviews Call BookMore Details
TownePlace Suites by Marriott St. Louis Edwardsville, IL
+1-888-389-4485
6101 Center Grove Rd., Edwardsville, IL 62025 ~31.67 miles west of Greenville
  • 3 star Suburban hotel
  • Hotel has 91 rooms
From$90
Very Good 4.0 /5 Read Reviews Call BookMore Details
Best Western Plus MidAmerica Hotel - Mascoutah
+1-888-389-4121
9730 Hayden Dr., Mascoutah, IL 62258 ~32.05 miles southwest of Greenville
  • Three Star Suburban hotel
  • Check-in: 3:00PM
From$69
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Okawville : 812 North Henhouse Rd.
+1-888-675-2083
812 North Henhouse Rd., Okawville, IL 62271 ~32.28 miles south of Greenville
  • Cheap Rural property
  • Check in time: 2pm
From$64
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Okawville in Okawville
+1-800-716-8490
812 North Hen House Rd., Okawville, IL 62271 ~32.28 miles south of Greenville
  • Cheap property
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham O'fallon in Ofallon
+1-800-805-5223
1100 Eastgate Dr., Ofallon, IL 62269 ~33.41 miles southwest of Greenville
  • Inexpensive Suburban property
  • Hotel has 2 floors
From$40
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn Edwardsville - St. Louis : 3080 South State Rte 157
+1-888-965-1860
3080 South State Rte 157, Edwardsville, IL 62025 Website ~33.44 miles west of Greenville
  • Economy Highway hotel
  • Hotel has 4 floors
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn & Suites St. Louis Edwardsville in Glen Carbon
+1-888-788-5576
5723 Heritage Crossing Dr., Glen Carbon, IL 62034 ~33.74 miles west of Greenville
  • 3-star Suburban property
  • Hotel has 72 rooms
From$99
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Best Western U. S. Inn in Nashville
+1-888-897-9207
11640 State Route 127, Nashville, IL 62263 ~35.22 miles south of Greenville
  • Midscale Highway property
  • 2 floors in hotel
From$62
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Sleep Inn O Fallon Il in O'fallon
+1-888-311-4278
140 Venita Dr., O'fallon, IL 62269 ~35.35 miles southwest of Greenville
  • 3-star Suburban property
  • Hotel has 3 floors
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG - Shiloh
+1-888-469-4795
3396 Green Mt. Crossing Dr., Shiloh, IL 62269 ~35.49 miles southwest of Greenville
  • Midscale Highway property
  • 80 rooms in property
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Inn & Suites Ofallon St. Louis Area in O'fallon
+1-888-734-9421
116 Regency Park, O'fallon, IL 62269 ~35.51 miles southwest of Greenville
  • Economical Suburban hotel
  • 66 rooms in property
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn O'fallon Il in O'fallon
+1-888-841-5292
430 Regency Park, O'fallon, IL 62269 ~35.57 miles southwest of Greenville
  • 3 star Suburban property
  • Hotel has 4 floors
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis in O'fallon
+1-888-455-5160
136 Regency Park, O'fallon, IL 62269 ~35.59 miles southwest of Greenville
  • Economy Suburban property
  • 2 floors in hotel
From$60
Average 3.0 /5 Reviews Call BookMore Details
Hilton Garden Inn St. Louis Shiloh / O'fallon Il
+1-888-965-8297
360 Regency Park, O'fallon, IL 62269 ~35.65 miles southwest of Greenville
  • Midscale Suburban hotel
  • Gym / Fitness Center Available
From$80
Average 3.0 /5 Reviews Call BookMore Details
Extended Stay America Select Suites - St. Louis - O' Fallon, IL in O'fallon
+1-888-906-6358
154 Regency Park, O'fallon, IL 62269 ~35.68 miles southwest of Greenville
  • Low-priced Highway property
  • Hotel has 3 floors
From$39
Average 3.0 /5 Review Score Call BookMore Details
Welcome Suites - O'fallon
+1-888-749-6785
148 Regency Park, O'fallon, IL 62269 ~35.68 miles southwest of Greenville
  • Two-star Suburban hotel
  • 89 sleeping rooms in hotel
From$40
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Towneplace Place Suites by Marriott St. Louis O Fallon Illinois
+1-888-878-9982
445 Regency Park Dr., Ofallon, IL 62269 ~35.68 miles southwest of Greenville
  • 3 star property
  • Hotel has 5 floors
From$90
Very Good 4.0 /5 Read Reviews Call BookMore Details

Next: See My Greenville Hotels with Pricing

Graph: Upcoming 20 Days of Greenville Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Greenville, IL discounts available. The chart reflects the cheapest Greenville hotel for each day and each star rating category.

FAQs about hotels in Greenville

What are the top reviewed hotels in Greenville?

Holiday Inn Express & Suites Salem by Ihg, Quality Inn & Suites Vandalia near I-70 and Hwy 51 and Quality Inn Litchfield Route 66 are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Greenville?

Holiday Inn Express & Suites Vandalia Il, Innkeeper Motel and Hampton Inn Litchfield are the top 3 luxury hotels near Greenville city center.

What hotels are closest to the city center of Greenville?

Super 8 by Wyndham Greenville, SureStay by Best Western Greenville, and Comfort Inn & Suites Greenville I-70 are the properties closest to Greenville city center.

What are the best independent hotels in Greenville?

Mariner's Village Resort & Inn, Magnuson Grand Hotel And Conference Center and Welcome Suites are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Greenville?

TownePlace Suites by Marriott St. Louis Edwardsville, IL and Towneplace Place Suites by Marriott St. Louis O Fallon Illinois are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Greenville?

Quality Inn & Suites Vandalia near I-70 and Hwy 51, Quality Inn Litchfield Route 66 and Comfort Inn & Suites Greenville I-70 are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular Best Western hotels in Greenville?

Best Western Plus Centralia Hotel & Suites, Best Western Plus MidAmerica Hotel and Best Western U. S. Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the most popular IHG hotels in Greenville?

Holiday Inn Express & Suites Salem by Ihg, Holiday Inn Express Troy by IHG and Holiday Inn Express & Suites Litchfield West by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Great Diner!"
Score 4.0 / 5

Vicky's Cafe was awesome!! Very helpful and polite staff! Clean diner with great food!

Amy S., from 24-Aug-2025
"Dressed up Strip area."
Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025
"Quiet Area"
Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024
"Proximity to Carlyle"
Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024
"Greenville has some excellent museums!"
Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023
"Great Aquarium"
Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023
"College Campus"
Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023
"Loved It!"
Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022
The average traveler rating of the city of Greenville, IL shown above is 4.4 out of 5 based on 8 reviews
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