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Seneca South Carolina Hotels & Motels

Only hotels in Seneca are listed below. Search for cheap and discounted hotel and motel rates in or near Seneca, SC for your upcoming personal or group trip. We provide the best Seneca, South Carolina motel and hotel rooms. Browse the Seneca area hotels to find the perfect lodging! Please use the provided map of the Seneca hotels. Group booking? Search Seneca Group Hotel Discounts

The Seneca center point is about 6 miles west of Memorial Stadium and 6 miles west of Clemson Amtrak Station.

Known for its friendly atmosphere and small-town charm, Seneca, South Carolina, is just 10 miles west of Clemson. Whether you're visiting for work or fun, you'll appreciate the city's welcoming vibe, historic district, and beautiful setting. Get to know the City of Smiles and find out where to stay in Seneca. More from this guide...

Seneca Hotels/Accommodations

Best Western Executive Inn in Seneca
+1-888-690-5247
511 Bypass Highway 123, Seneca, SC 29678-0845
  • 3-star Rural hotel
  • 3 floors in hotel
Hampton Inn & Suites in Seneca
+1-888-305-3366
1011 East North 1st St., Seneca, SC 29678
  • Three Star hotel
From$129
Very Good 4.5 /5Hotel Reviews CallBookMore Details
Quality Inn - Seneca
+1-800-881-1523
226 Hi Tech Rd., Seneca, SC 29678
  • Three Star property
  • 62 sleeping rooms in hotel
TRU by Hilton Seneca Clemson in Seneca
+1-888-283-3404
13050 Clemson Blvd., Seneca, SC 29678
  • Mid-scale Lake hotel
  • Hotel has 98 rooms
Hampton Inn : 851 Tiger Blvd.
+1-866-221-8581
851 Tiger Blvd., Clemson, SC 29631 ~5.99 miles east of Seneca
  • 3-star Suburban hotel
  • Access to gym on-site
  • Easy check in
  • Close to resteraunts
From$104
Very Good 4.5 /5Latest Reviews CallBookMore Details
James F Martin Inn at Clemson Univ.
+1-866-429-5787
240 Madren Center Dr., Clemson, SC 29634 ~6.41 miles east of Seneca
  • Three Star hotel
  • Check in: 15:00
Holiday Inn Express & Suites (Clemson University & Seneca Area) - Clemson
+1-888-690-5281
1381 Tiger Blvd., Clemson, SC 29631 ~6.80 miles east of Seneca
  • 3 star Downtown property
  • Hotel has an eco-friendly policy See policy
From$109
Very Good 4.5 /5Hotel Reviews CallBookMore Details
Hotel Tillman Univ. Area
+1-888-690-5247
1303 Tiger Blvd., Clemson, SC 29631 ~6.80 miles east of Seneca
  • Inexpensive hotel
  • 3 floors in hotel
Days Inn - Clemson
+1-888-305-3366
1387 Tiger Blvd., Clemson, SC 29631 ~6.80 miles east of Seneca
  • Cheap property
  • 46 sleeping rooms in hotel
  • Quick checkin
  • For 87%, the rooms looked old
Comfort Inn Clemson S.c. (Clemson University & Seneca Area) : 1305 Tiger Blvd.
+1-800-881-1523
1305 Tiger Blvd., Clemson, SC 29631 Website ~7.12 miles east of Seneca
  • Midscale Downtown hotel
  • Complimentary breakfast is offered
  • Housekeeping was great, according to 100%
  • Almost all guests said the reception staff was ok
Best Western Plus University Inn & Conference Center - Clemson
+1-888-283-3404
1310 Tiger Blvd., Clemson, SC 29631-1114 ~7.28 miles east of Seneca
  • Two-star Downtown property
  • Check in time: 04:00
  • Average sized rooms
  • Staff apologized
Rodeway Inn - Walhalla
+1-866-221-8581
901 East Main St., Walhalla, SC 29691 ~7.87 miles northwest of Seneca
  • Cheap Mountain property
  • Check-in: 02:00 PM
Courtyard Clemson in Clemson
+1-866-429-5787
201 Canoy Lane, Clemson, SC 29631 Website ~7.93 miles east of Seneca
  • Affordable property
  • Check-in: 3:00pm
From$114
Very Good 4.5 /5Review Score CallBookMore Details
America's Best Inn Clemson in Clemson
+1-888-690-5281
106 Liberty Dr., Clemson, SC 29631 ~8.08 miles east of Seneca
  • Two-star property
Hampton Inn Anderson
+1-888-690-5247
120 Insterstate Blvd., Anderson, SC 29621 ~13.07 miles southeast of Seneca
  • Affordable Highway property
  • 72 rooms in hotel
  • Fair price
  • Clean
Microtel Inn & Suites
+1-888-305-3366
102 Electric City Blvd., Anderson, SC 29621 ~15.54 miles east of Seneca
  • 2-star Highway property
  • 4 floors in property
From$58
Very Good 4.0 /5Read Reviews CallBookMore Details
Country Inn & Suites - Anderson
+1-800-881-1523
116 Interstate Blvd., Anderson, SC 29621 ~15.61 miles east of Seneca
  • Mid-scale Highway hotel
  • Check in: 3:00 pm
  • Good accessibility by car
  • Great desserts & fruits
From$65
Very Good 4.5 /5Reviews CallBookMore Details
Fairfield Inn & Suites by Marriott Anderson Clemson
+1-888-283-3404
117 Interstate Blvd., Anderson, SC 29621 ~15.61 miles east of Seneca
  • Three Star property
  • Check-in: 16:00
Holiday Inn Express & Suites - Anderson
+1-866-221-8581
107 Interstate Blvd., Anderson, SC 29621 ~15.64 miles east of Seneca
  • Inexpensive Highway hotel
  • Hotel has 75 rooms
Comfort Suites
+1-866-429-5787
118 Interstate Blvd., Anderson, SC 29621 ~15.73 miles east of Seneca
  • Low priced Highway hotel
  • 4 floors in hotel
  • High comfort
  • Room is all right
From$64
Very Good 4.0 /5Review Score CallBookMore Details
Rodeway Inn : 4515 Clemson Blvd.
+1-888-690-5281
4515 Clemson Blvd., Anderson, SC 29621 ~15.94 miles southeast of Seneca
  • Two-star hotel
  • 50 sleeping rooms in hotel
Baymont by Wyndham Anderson Clemson
+1-888-690-5247
128 Interstate Blvd., Anderson, SC 29621 ~15.97 miles east of Seneca
  • 2-star Highway hotel
  • Gym / Fitness Center Available
Days Inn Anderson in Anderson
+1-888-305-3366
1007 Smith Mill Rd., Anderson, SC 29625 ~16.04 miles southeast of Seneca
  • Low priced Highway hotel
  • Check in: 11:00 AM
From$50
Average 3.0 /5Reviews CallBookMore Details
Days Inn by Wyndham Anderson
+1-800-881-1523
1007 George Smith Mill Rd., Anderson, SC 29625 ~16.04 miles southeast of Seneca
  • Economy hotel
Hilton Garden Inn Anderson in Anderson
+1-888-283-3404
115 Destination Blvd., Anderson, SC 29621 ~16.11 miles southeast of Seneca
  • Affordable Highway hotel
  • Fitness / Gym is on-site
From$107
Very Good 4.5 /5Read Reviews CallBookMore Details
Next 25 Seneca Hotels >  [1 - 25 of 50]    
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Graph: Upcoming 20 Days of Seneca Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Seneca, SC discounts available. The chart reflects the cheapest Seneca hotel for each day and each star rating category.

When should you visit Seneca, SC?

To experience the city at its liveliest, don't miss Seneca Fest. This annual event takes place at the end of May and features a full lineup of musical performances, action-packed wrestling matches, and family-friendly activities.

To plan your trip around the area's best weather, consider visiting during the spring or fall when high temperatures usually top out in the low 80s or high 70s. Summers can get very hot in Seneca, with highs in the 90s, and winters can get chilly, with lows around 30. Although August tends to be the wettest month of the year, winter is rainy season in Seneca. If you visit during the winter, bundle up and wear a waterproof jacket to stay warm and dry.

Winter is low season in Seneca, and you're most likely to find great discounts on hotels in January or February. For low rates on accommodations during high season, start planning in advance, and look for group rates.

Below is a chart of the current pricing seasonality of hotels and motels in Seneca, SC:

seasonality of hotel rates in Seneca

Averate Rates by Star Rating

Below we've posted 3 graphs displaying average nightly cost patterns by star rating class in Seneca, SC. Analyze these charts to evaluate the best time to make a reservation in Seneca for your upcoming travels.

Where are the top luxury hotel options in Seneca, SC?

Want to treat your group to an upscale stay in the Seneca area? Check out the best high-end hotels.

Located in the heart of Seneca, the Hampton Inn & Suites is ideal for both business and leisure travelers. When you stay here, you can keep it simple with a standard room or upgrade to a suite with a sofa bed, microwave, and mini-fridge. You'll appreciate the hotel's contemporary decor, the convenient location near U.S. 123, and complimentary coffee 24/7. Start your day with freshly baked waffles and hearty oatmeal at the Hampton Inn's free breakfast buffet, or take an On the Run breakfast bag to go.

When you want to ensure that you have access to a full range of features, book your stay at the Holiday Inn Express & Suites (Clemson / Seneca Area). This downtown Clemson hotel has a gym to help you stay in shape, an indoor pool that's perfect for families, and a free breakfast buffet that your entire group will appreciate. With eggs, bacon, cinnamon rolls, and freshly brewed coffee, this is a buffet that won't disappoint. Planning an event in the Seneca area? Book the 1,300-square-foot meeting space, which holds up to 80 people.

With its convenient location near Interstate 85, Country Inn & Suites in Anderson is ideal for an upscale stay minutes from the Seneca area's best attractions and outdoor recreation. Both standard rooms and suites come with mini-fridges, microwaves, coffee makers, and flat-screen TVs with premium channels. Go for a swim in the indoor pool, get some reading material from the hotel's lending library, and treat yourself to fresh cookies in the lobby. Don't miss the free breakfast, which includes biscuits and gravy, French toast, waffles, and much more.

What are the budget-friendly hotels worth booking in Seneca, South Carolina?

3 Star Average Prices: $102.17

Visiting Seneca on a budget? Book one of the area's top-rated affordable accommodations.

When you stay at the Days Inn in Clemson, you'll be minutes from Seneca and U.S. Highway 123. This budget-friendly hotel offers easy access to local attractions as well as rooms with free Wi-Fi, coffee makers, and microwaves. Use the business center to catch up on emails, use the free Wi-Fi to plan out your day, and start your morning with the hotel's free Daybreak Breakfast. If you're traveling with a furry family member, you'll appreciate the Days Inn's pet-friendly policy.

Located a short drive east of Seneca, Microtel Inn & Suites offers quick access to Interstate 85 and bustling Anderson. Whether you choose a standard room or a suite, you can look forward to a clean, spacious room equipped with a flat-screen TV and complimentary Wi-Fi. Upgrade to a suite for extras like a mini-fridge, a microwave, and a coffee maker. Take a dip in the outdoor saltwater pool, help yourself to free coffee around the clock, and wake up to the hotel's free breakfast spread.

Nestled in Walhalla, just west of Seneca, the Walhalla Motel offers 18 affordably priced rooms with the basics. Kick back and catch up on your favorite movies on HBO or use the wireless internet access to stay in touch with family and friends. In-room microwaves and mini-fridges let you keep snacks and drinks on hand so you can keep your dining costs low during your trip. When you're ready to head out and explore the surrounding area, you'll find dining and shopping just a half mile away.

3 Star Hotel Prices in Seneca

2 Star Average Prices: $75.99

2 Star Hotel Prices in Seneca

What hotels in Seneca, SC offer the best discounts?

Looking for the best deals and discounts on Seneca hotels? Browse some of the best group rates in the area.

Senior travelers and AARP members can get discounts at the Best Western Executive Inn in Seneca. This centrally located hotel has both suites and standard rooms, and you'll appreciate the outdoor pool and the complimentary breakfast served each morning.

AAA members can get low rates at the Baymont Inn & Suites in Anderson. This mid-range hotel has a long list of extras, including free breakfast, a fitness center, an outdoor pool, and a meeting room available for reservation.

Government employees and members of the military can save at the Rodeway Inn in nearby Anderson. This budget-friendly hotel has 50 affordable rooms with basics like mini-fridges, microwaves, and coffee makers, and the hotel offers easy access to Interstate 85.

Where are the hotels with the most value in Seneca, South Carolina

It's easy to balance price with amenities when you book one of the best value options in Seneca. Take a look at the area's best mid-range hotels.

When you want to stay in the heart of Seneca, the Quality Inn offers plenty of value in a convenient location. This mid-range hotel has over 60 well-equipped guest rooms, along with a fitness center, an outdoor pool, and free Wi-Fi. You'll love the signature Q Beds, and after a great night's sleep, you'll be ready to dig into the complimentary breakfast spread. This Quality Inn welcomes up to two pets per room, making it easy to travel with your furry family members.

Nestled in nearby Clemson, the Best Western Plus University Inn & Conference Center is a smart choice for both leisure and business travelers. Settle into your modern guest room, grab a bite to eat at the full-service restaurant, and catch up on work in the business center. This Best Western also has six available conference rooms and an average group discount of over 20 percent, making this mid-range hotel excellent for groups visiting the Seneca area.

Also located in Clemson, Comfort Inn Clemson SC (Clemson University & Seneca Area) features three meeting rooms and an average group discount of over 15 percent. This mid-range hotel has guest rooms equipped with microwaves, coffee makers, and mini-fridges as well as an outdoor pool that's ideal for cooling off on a hot summer day. In the morning, don't miss the free breakfast bar, which includes biscuits and gravy, fresh waffles, pastries, and coffee.

What can't-miss attractions should you see in Seneca, SC?

With its equal doses of historical charm and natural beauty, Seneca has a little something for every visitor. Take a stroll through the Seneca Historic District to enjoy this South Carolina gem's small-town appeal and marvel at the many homes and churches that date back to the 19th century.

Located in the heart of the Seneca Historic District, the Lunney House Museum is an essential stop for history buffs. A stunning example of the architecture that defined the New South in the early 20th century, this home features impressive details like a sparkling chandelier, an intricately carved oak mantel, a 19th-century grand piano, and art glass windows. Take a self-guided tour of the house museum or check the museum's calendar for special events.

To gain a more comprehensive picture of Seneca's history, you'll also want to visit the Bertha Lee Strickland Cultural Museum. This fascinating museum explores the history of African-American culture and Oconee County residents through a variety of permanent and temporary exhibitions.

If you're traveling with kids in tow, you'll also want to visit the World of Energy at Oconee Nuclear. This interactive museum is a fun place for kids of all ages to learn about electricity, energy, and local nature and wildlife.

Next, experience Seneca's natural beauty firsthand with a visit to South Cove County Park. Located on the shores of Lake Keowee, this park is perfect for swimming, sunbathing, boating, and fishing. You can also take advantage of the tennis courts, picnic areas, and playgrounds all year round. If you didn't bring your own boat, you'll find canoe, kayak, and pontoon boat rentals at Lake Keowee Marina and many other local spots.

Why wait to book your trip? Find the ideal place to stay and start designing your Seneca itinerary.

FAQs about hotels in Seneca

What are the best rated hotels in Seneca?

Hampton Inn & Suites, TRU by Hilton Seneca Clemson and Hampton Inn are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Seneca?

Best Western Executive Inn, Hampton Inn & Suites and Quality Inn are the top 3 luxury hotels near Seneca city center.

What hotels are closest to the city center of Seneca?

Best Western Executive Inn, Hampton Inn & Suites, and Quality Inn are the properties closest to Seneca city center.

How much does a cheap hotel in Seneca cost per night?

In the last year, a 2 star hotel in Seneca can be as cheap as $75.99 per night. (based on HotelPlanner prices)

How much does a 3 star hotel in Seneca cost per night?

In the last year, the average 3 star hotel in Seneca has been $102.17 per night. (based on HotelPlanner prices)

What are the most popular independent hotels in Seneca?

Lake Hartwell Inn & Suites, Hotel Tillman Univ. Area and Kingwood Resort are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Seneca?

Courtyard Clemson and Fairfield Inn & Suites by Marriott Anderson Clemson are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels in Seneca?

Comfort Inn Clemson S.c. (Clemson University & Seneca Area), Comfort Suites and Quality Inn are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular Best Western hotels in Seneca?

Best Western Executive Inn, Best Western Plus University Inn & Conference Center and Best Western Plus Greenville South are the best rated Best Western branded hotels (based on user reviews score).

What are the most popular IHG hotels in Seneca?

Holiday Inn Express & Suites (Clemson University & Seneca Area), Holiday Inn Anderson and Holiday Inn Express & Suites are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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