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Seneca South Carolina Hotels & Motels

Only hotels in Seneca are listed below. Search for cheap and discounted hotel and motel rates in or near Seneca, SC for your upcoming personal or group trip. We provide the best Seneca, South Carolina motel and hotel rooms. Browse the Seneca area hotels to find the perfect lodging! Please use the provided map of the Seneca hotels. Group booking? Search Seneca Group Hotel Discounts

The Seneca center point is about 6 miles west of Memorial Stadium and 6 miles west of Clemson Amtrak Station.

Seneca Hotels/Motels & Accommodations

Best Western Executive Inn : 511 Byp Highway 123 511 Byp Highway 123, Seneca, SC 29678
  • Three Star Rural property
  • Check-in time: 02:00
From$80
Very Good 4.0 /5Read Reviews CallBookMore Details
Hampton Inn & Suites 1011 East North 1st St., Seneca, SC 29678
  • Affordable hotel
From$129
Very Good 4.5 /5Recent Reviews CallBookMore Details
Quality Inn : 226 Hi Tech Rd. 226 Hi Tech Rd., Seneca, SC 29678
  • Midscale hotel
  • Fitness center on property
Hampton Inn 851 Tiger Blvd., Clemson, SC 29631 ~5.99 miles east of Seneca
  • Affordable Suburban property
  • Fitness center on property
  • Clean hotel facilities
  • Close to campus
From$109
Very Good 4.5 /5Read Reviews CallBookMore Details
James F Martin Inn at Clemson Univ. 240 Madren Center Dr., Clemson, SC 29634 ~6.41 miles east of Seneca
  • 3-star hotel
Holiday Inn Express & Suites (Clemson / Seneca Sc Area) : 1381 Tiger Blvd. 1381 Tiger Blvd., Clemson, SC 29631 ~6.80 miles east of Seneca
  • 3 star Downtown property
  • Complimentary breakfast is offered
Hotel Tillman Univ. Area : 1303 Tiger Blvd. 1303 Tiger Blvd., Clemson, SC 29631 ~6.80 miles east of Seneca
  • Cheap hotel
  • 57 sleeping rooms in hotel
Days Inn
+1-888-690-5247
1387 Tiger Blvd., Clemson, SC 29631 ~6.80 miles east of Seneca
  • Cheap property
  • Check in time: 03.00PM
  • No smoking room
  • Most guests thought they were poorly maintained
Comfort Inn Clemson S.c. (Clemson University & Seneca Area) in Clemson 1305 Tiger Blvd., Clemson, SC 29631 ~7.12 miles east of Seneca
  • Mid-scale Downtown hotel
  • Hotel has a green policy Learn more
  • The majority of guests criticized the small bathroom
  • Clean stay
From$75
Very Good 4.0 /5Review Score CallBookMore Details
Best Western Plus University Inn & Conference Center 1310 Tiger Blvd., Clemson, SC 29631 ~7.28 miles east of Seneca
  • Economical Downtown hotel
  • 6 conference rooms in property
  • Most guests thought, the hotel was modern
  • Almost all guests found the staff to be very friendly
From$75
Very Good 4.0 /5Review Score CallBookMore Details
Walhalla Motel : 901 East Main St.
+1-888-283-3404
901 East Main St., Walhalla, SC 29691 ~7.87 miles northwest of Seneca
  • Inexpensive Mountain property
  • Hotel has 18 rooms
Courtyard Clemson 201 Canoy Lane, Clemson, SC 29631 ~7.93 miles east of Seneca
  • Midscale hotel
  • Check-in: 3:00pm
From$114
Very Good 4.5 /5Latest Reviews CallBookMore Details
America's Best Inn Clemson : 106 Liberty Dr. 106 Liberty Dr., Clemson, SC 29631 ~8.08 miles east of Seneca
  • Low Cost property
Hampton Inn Anderson in Anderson 120 Insterstate Blvd., Anderson, SC 29621 ~13.07 miles southeast of Seneca
  • Affordable Highway hotel
  • Hotel has 3 floors
  • All guests thought the service was very professional
  • Clean rooms
From$84
Very Good 4.5 /5Reviews CallBookMore Details
Microtel Inn & Suites in Anderson 102 Electric City Blvd., Anderson, SC 29621 ~15.54 miles east of Seneca
  • Inexpensive Highway property
  • 16 suites in property
From$57
Very Good 4.0 /5Reviews CallBookMore Details
Holiday Inn Express & Suites Anderson & Clemson 107 Interstate Blvd., Anderson, SC 29621 ~15.58 miles east of Seneca
  • Midscale Highway hotel
  • 3 floors in property
  • Clean hotel in an excellent location
  • Clean rooms
Country Inn & Suites 116 Interstate Blvd., Anderson, SC 29621 ~15.61 miles east of Seneca
  • Midscale Highway hotel
  • 55 rooms in property
  • Receptionist was very attentive
  • Reception is all right
From$74
Very Good 4.5 /5Read Reviews CallBookMore Details
Baymont Inn & Suites 128 Interstate Blvd., Anderson, SC 29621 ~15.65 miles east of Seneca
  • 3-star Highway property
  • Check in: 03:00pm
  • Most guests said rooms were small
  • Hotel could use some updating
Comfort Suites - Anderson 118 Interstate Blvd., Anderson, SC 29621 ~15.73 miles east of Seneca
  • Low Cost Highway property
  • Check in time: 3:00pm
  • Furniture needs more attention
  • Heating muffins
Rodeway Inn : 4515 Clemson Blvd. 4515 Clemson Blvd., Anderson, SC 29621 ~15.94 miles southeast of Seneca
  • Cheap hotel
  • 50 rooms in hotel
Days Inn Anderson 1007 Smith Mill Rd., Anderson, SC 29625 ~16.04 miles southeast of Seneca
  • Cheap Highway hotel
  • Free breakfast
Hilton Garden Inn Anderson in Anderson 115 Destination Blvd., Anderson, SC 29621 ~16.11 miles southeast of Seneca
  • 3 star Highway property
  • 124 sleeping rooms in hotel
From$101
Very Good 4.5 /5Latest Reviews CallBookMore Details
Americas Best Value Inn : 4020 Clemson Blvd. 4020 Clemson Blvd., Anderson, SC 29621 ~17.45 miles southeast of Seneca
  • Cheap hotel
  • 2 floors in property
Holiday Inn Anderson - Anderson 3509 Clemson Blvd., Anderson, SC 29621 ~18.40 miles southeast of Seneca
  • Midscale Downtown property
  • Check-in time: 3:00 PM
From$90
Very Good 4.5 /5Read Reviews CallBookMore Details
Home Towne Suites Anderson 151 Civic Center Blvd., Anderson, SC 29625 ~18.44 miles southeast of Seneca
  • Inexpensive Lake property
  • Fitness + Health Center
  • Horrible vibe
  • Did not have much interaction
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