62280 Hotels & Accommodations

Best Western Chester Hotel
+1-888-389-4121
2150 State St., Chester, IL 62233 +1-888-389-4121 ~12.06 miles northwest of 62280
  • 3 star Rural hotel
  • Check in: 1:00 PM
From$69
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale : 128 East Walnut St.
+1-888-675-2083
128 East Walnut St., Murphysboro, IL 62966 +1-888-675-2083 ~16.09 miles east of 62280
  • Inexpensive hotel
  • Check-in: 14:00
Super 8 by Wyndham Perryville
+1-800-716-8490
1119 Vincent Dr., Perryville, MO 63775 +1-800-716-8490 ~17.08 miles southwest of 62280
  • Two-star Highway property
  • 2 conference rooms in property
From$59
Very Good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Perryville
+1-800-805-5223
1500 Liberty St., Perryville, MO 63775 +1-800-805-5223 ~17.22 miles west of 62280
  • Two star Highway hotel
  • Check in: 3:00 PM
From$60
Average 3.5 /5 Latest Reviews Call BookMore Details
University Inn of Carbondale in Carbondale
+1-888-965-1860
2400 West Main St., Carbondale, IL 62901 +1-888-965-1860 ~21.46 miles east of 62280
  • Midscale property
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Sparta, an IHG Hotel
+1-888-788-5576
1301 North Market St., Sparta, IL 62286 +1-888-788-5576 ~21.82 miles north of 62280
  • Three Star Rural hotel
  • Hotel has a green policy See policy
From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Arrowrock Inn
+1-888-897-9207
17030 New Bremen Rd., Ste Genevieve, MO 63670 +1-888-897-9207 ~22.88 miles west of 62280
  • Cheap Rural hotel
  • Free breakfast available
From$49
Very Good 4.0 /5 Reviews Call BookMore Details
Home2 Suites by Hilton Carbondale
+1-888-311-4278
200 West Elm St., Carbondale, IL 62901 +1-888-311-4278 ~23.26 miles east of 62280
  • Midscale Downtown hotel
  • Fitness center on property
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
Americas Best Value Inn & Suites Pinckneyville - Pinckneyville
+1-888-469-4795
5700 State Route 154, Pinckneyville, IL 62274 +1-888-469-4795 ~23.40 miles northeast of 62280
  • Cheap property
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Train Inn
+1-888-734-9421
406 East Stoker St., Carbondale, IL 62901 +1-888-734-9421 ~23.72 miles east of 62280
  • 3-star Suburban property
  • Has environment-friendly policy See more
From$50
Very Good 4.0 /5 Read Reviews Call BookMore Details
Carbondale Value Inn & Suites in Carbondale
+1-888-841-5292
700 East Main St., Carbondale, IL 62901 +1-888-841-5292 ~23.73 miles east of 62280
  • Low Cost Downtown hotel
  • Hotel has 2 floors
From$54
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Du Quoin : 1010 S.jefferson Ave.
+1-888-455-5160
1010 S.jefferson Ave., Du Quoin, IL 62832 +1-888-455-5160 ~23.98 miles east of 62280
  • Low Cost hotel
  • Check-in: 3p
From$54
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Carbondale in Carbondale
+1-888-965-8297
1180 East Main St., Carbondale, IL 62901 +1-888-965-8297 ~24.28 miles east of 62280
  • Cheap hotel
  • Hotel has 63 rooms
From$58
Average 3.0 /5 Review Score Call BookMore Details
Best Western Saluki Inn
+1-888-906-6358
801 North Giant City Rd., Carbondale, IL 62902 +1-888-906-6358 ~24.73 miles east of 62280
  • 3-star Downtown hotel
  • 2 suites in hotel
From$79
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn Carbondale University Area in Carbondale
+1-888-749-6785
1415 East Main St., Carbondale, IL 62901 +1-888-749-6785 ~24.74 miles east of 62280
  • Mid-scale Suburban property
  • Complimentary breakfast is offered
Hampton Inn Carbondale - Carbondale
+1-888-878-9982
2175 Reed Station Pkwy., Carbondale, IL 62901 +1-888-878-9982 ~25.54 miles east of 62280
  • 3-star Rural hotel
  • Free comp. breakfast
From$80
Average 3.0 /5 Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Sainte Genevieve in Sainte Genevieve
+1-888-389-4485
21958 Highway 32, Sainte Genevieve, MO 63670 +1-888-389-4485 ~25.61 miles west of 62280
  • Low-priced Highway property
  • Hotel has 48 rooms
From$75
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Carbondale-Conference Center, an IHG Hotel : 2300 Reed Station Pkwy.
+1-888-389-4121
2300 Reed Station Pkwy., Carbondale, IL 62901 +1-888-389-4121 ~25.73 miles east of 62280
  • Mid-scale Rural hotel
  • Hotel has 6 meeting rooms
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
Comfort Inn & Suites Carbondale University Area : 2400 Reed Station Pkwy.
+1-888-675-2083
2400 Reed Station Pkwy., Carbondale, IL 62901 +1-888-675-2083 ~25.83 miles east of 62280
  • Three Star Suburban hotel
  • Hotel has 73 rooms
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Drury Inn & Suites Jackson Missouri : 225 Drury Lane
+1-800-716-8490
225 Drury Lane, Jackson, MO 63755 +1-800-716-8490 ~27.79 miles south of 62280
  • Three Star Suburban property
  • 130 rooms in hotel
From$79
Very Good 4.5 /5 Reviews Call BookMore Details
Comfort Suites Jackson-Cape Girardeau : 2904 Old Orchard Rd.
+1-800-805-5223
2904 Old Orchard Rd., Jackson, MO 63755 +1-800-805-5223 ~32.83 miles south of 62280
  • 3 star Highway hotel
  • Fitness + Health Center
From$65
Average 3.0 /5 Recent Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau : 3003 South Old Orchard Rd.
+1-888-965-1860
3003 South Old Orchard Rd., Jackson, MO 63755 +1-888-965-1860 ~33.02 miles south of 62280
  • Three Star Highway property
  • Gym / Fitness Center Available
From$85
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hotel 7 Inn Anna : 100 Richview Dr.
+1-888-788-5576
100 Richview Dr., Anna, IL 62906 +1-888-788-5576 ~33.15 miles southeast of 62280
  • Low priced property
From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Motel 6 Marion Il - Marion
+1-888-897-9207
8101 Express Dr., Marion, IL 62959 +1-888-897-9207 ~33.88 miles east of 62280
  • Economical Airport hotel
  • Check-in time: 3:00pm
From$65
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn in Cape Girardeau
+1-888-311-4278
2011 North Kingshighway St., Cape Girardeau, MO 63701 +1-888-311-4278 ~34.19 miles south of 62280
  • Economy property
  • Hotel has 2 floors
From$60
Very Good 4.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Marion in Marion
+1-888-469-4795
2608 West Main, Marion, IL 62959 +1-888-469-4795 ~35.76 miles east of 62280
  • Affordable Highway hotel
  • Hotel has an eco-friendly policy Read more
From$54
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Inn & Suites Marion I 57 : 2403 Black Diamond Dr.
+1-888-734-9421
2403 Black Diamond Dr., Marion, IL 62959 +1-888-734-9421 ~36.15 miles east of 62280
  • Three Star Golf Course hotel
  • Hotel has 11 suites
From$119
Average 3.0 /5 Latest Reviews Call BookMore Details
Drury Inn Marion : 2706 West Deyoung
+1-888-841-5292
2706 West Deyoung, Marion, IL 62959 +1-888-841-5292 ~36.17 miles east of 62280
  • Midscale Suburban hotel
  • Hotel has a green policy Read more
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Marion
+1-888-455-5160
2710 West Deyoung St., Marion, IL 62959 +1-888-455-5160 ~36.18 miles east of 62280
  • Mid-scale Rural hotel
  • 3 suites in property
From$91
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Country Inn & Suites by Radisson, Marion, IL
+1-888-965-8297
1306 Halfway Rd., Marion, IL 62959 +1-888-965-8297 ~36.30 miles east of 62280
  • 3 star Airport property
  • Comp. Breakfast
From$80
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau in Cape Girardeau
+1-888-906-6358
3351 Percy Dr., Cape Girardeau, MO 63701 +1-888-906-6358 ~36.30 miles south of 62280
  • Mid-scale hotel
  • Check in: 3pm
From$59
Average 3.0 /5 Latest Reviews Call BookMore Details
Drury Lodge : 104 South Vantage Dr.
+1-888-749-6785
104 South Vantage Dr., Cape Girardeau, MO 63701 +1-888-749-6785 ~36.32 miles south of 62280
  • 3 star Highway hotel
  • Access to gym on-site
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Marion in Marion
+1-888-878-9982
1400 Champion Dr., Marion, IL 62959 +1-888-878-9982 ~36.34 miles east of 62280
  • Mid-scale Highway property
  • Free breakfast
From$94
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express Hotel & Suites Marion Northeast An Ihg Hotel
+1-888-389-4485
2609 Blue Heron Dr., Marion, IL 62959 +1-888-389-4485 ~36.41 miles east of 62280
  • Affordable property
  • 4 floors in hotel
From$82
Very Good 4.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Marion
+1-888-389-4121
2601 Vernell Rd., Marion, IL 62959 +1-888-389-4121 ~36.50 miles east of 62280
  • Economical Rural property
  • Check in time: 2:00pm
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center in Cape Girardeau
+1-888-675-2083
3248 William St., Cape Girardeau, MO 63701 +1-888-675-2083 ~36.54 miles south of 62280
  • Low Cost Highway hotel
  • Has environment-friendly policy Learn more
From$66
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Drury Suites Cape Girardeau : 3303 Campster Dr.
+1-800-716-8490
3303 Campster Dr., Cape Girardeau, MO 63701 +1-800-716-8490 ~36.54 miles south of 62280
  • Three Star Highway hotel
  • Hotel has an eco-friendly policy See more
From$85
Very Good 4.5 /5 Review Score Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown in Cape Girardeau
+1-800-805-5223
400 Broadway St., Cape Girardeau, MO 63701 +1-800-805-5223 ~36.58 miles south of 62280
  • 3 star Downtown property
  • Access to gym on-site
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Auburn Place Hotel & Suites
+1-888-965-1860
3265 Williams St., Cape Girardeau, MO 63702 +1-888-965-1860 ~36.59 miles south of 62280
  • 3 star Highway hotel
  • 133 sleeping rooms in hotel
From$58
Very Good 4.5 /5 Review Score Call BookMore Details
Victorian Inn & Suites : 3256 William St.
+1-888-788-5576
3256 William St., Cape Girardeau, MO 63703 +1-888-788-5576 ~36.60 miles south of 62280
  • 3-star Golf Course property
  • 5 suites in property
From$79
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn And Suites
+1-888-897-9207
2600 West Main, Marion, IL 62959 +1-888-897-9207 ~36.63 miles east of 62280
  • Cheap Highway hotel
  • Hotel has 2 floors
From$49
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 in Cape Girardeau
+1-888-311-4278
3253 William St., Cape Girardeau, MO 63701 +1-888-311-4278 ~36.64 miles south of 62280
  • Affordable property
  • Gym / Fitness Center Available
From$80
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West
+1-888-469-4795
103 Cape West Pkwy., Cape Girardeau, MO 63701 +1-888-469-4795 ~36.66 miles south of 62280
  • Inexpensive hotel
  • 81 rooms in property
From$59
Average 3.0 /5 Reviews Call BookMore Details
Best Western Marion Hotel in Marion
+1-888-734-9421
400 Comfort Dr., Marion, IL 62959 +1-888-734-9421 ~36.73 miles east of 62280
  • Three Star Highway property
  • 3 floors in hotel
From$67
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East : 207 South Mount Auburn Rd.
+1-888-841-5292
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 +1-888-841-5292 ~36.73 miles south of 62280
  • Three Star Highway property
  • Complimentary breakfast is offered
From$80
Excellent 5.0 /5 Review Score Call BookMore Details
Americas Best Value Inn West Frankfort
+1-888-455-5160
1001 Factory Outlet Blvd., West Frankfort, IL 62896 +1-888-455-5160 ~36.83 miles east of 62280
  • 2-star hotel
  • Free complimentary breakfast
From$46
Average 3.5 /5 Recent Reviews Call BookMore Details
Americas Best Value Inn Marion, IL : 1802 Bittle Place
+1-888-965-8297
1802 Bittle Place, Marion, IL 62959 +1-888-965-8297 ~37.24 miles east of 62280
  • Cheap hotel
  • 2 floors in property
From$60
Very Good 4.0 /5 Read Reviews Call BookMore Details
Econo Lodge - Marion
+1-888-906-6358
1806 Bittle Place, Marion, IL 62959 +1-888-906-6358 ~37.25 miles east of 62280
  • Cheap Lake hotel
  • Access to gym on-site
From$54
Average 3.0 /5 Latest Reviews Call BookMore Details
Candlewood Suites Cape Girardeau, an IHG Hotel : 485 South Mount Auburn Rd.
+1-888-749-6785
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 +1-888-749-6785 ~37.43 miles south of 62280
  • Two star Highway hotel
  • Hotel has 4 floors
From$69
Very Good 4.0 /5 Reviews Call BookMore Details
Country Garden & Suites
+1-888-878-9982
711 West Main St., Benton, IL 62812 +1-888-878-9982 ~39.29 miles east of 62280
  • Cheap property
  • Hotel has 43 rooms
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