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Lake City South Carolina Accommodations

Find the perfect hotel in Lake City using our hotel guide provided below. Find discounted hotel accommodations in or close to Lake City, SC for your personal leisure or group travel. Discover the most favored Lake City South Carolina hotel/motel rooms. Review the Lake City hotel list below to find the perfect lodging. We also have a map of the Lake City hotels. Coordinating a group? Get Lake City Group Hotel Rates

The Lake City center is approximately 12 miles northeast of Williamsburg County Airport and 14 miles north of Kingstree Amtrak Station.

Lake City Hotels/Accommodations

Inn at the Crossroads
+1-888-389-4121
128 West Main St., Lake City, SC 29560
  • Low-priced Downtown property
  • 6 suites in hotel
From$109
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
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Days Inn by Wyndham Lake City in Lake City
+1-888-675-2083
170 South Ron Mcnair Blvd., Lake City, SC 29560
  • 2 star Downtown hotel
  • Check in: 02.00 PM
From$60
Average 3.5 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites
+1-800-716-8490
202 North Ron Mcnair Blvd., Lake City, SC 29560
  • Midscale hotel
  • Check in time: 15:00
From$80
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Inn
+1-800-805-5223
1610 North Longstreet St., Kingstree, SC 29556 ~13.47 miles south of Lake City
  • Three Star Highway hotel
  • 46 sleeping rooms in hotel
From$80
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Turbeville
+1-888-965-1860
7835 Myrtle Beach Highway, Gable, SC 29051 ~20.05 miles west of Lake City
  • Two-star property
  • Check-in: 12:00 PM
Travelodge by Wyndham Florence : 3783a West Palmetto St.
+1-888-788-5576
3783a West Palmetto St., Florence, SC 29501 ~21.41 miles north of Lake City
  • Low Cost Highway property
  • Hotel has 120 rooms
From$58
Not Good 1.0 /5 Hotel Reviews Call BookMore Details
Days Inn Florence : 3783 West Palmetto St. I 95
+1-888-897-9207
3783 West Palmetto St. I 95, Florence, SC 29501 ~21.42 miles north of Lake City
  • Cheap Highway property
  • 120 rooms in hotel
Travelodge by Wyndham Florence : 1084 Oregon Coast Highway
+1-888-311-4278
1084 Oregon Coast Highway, Florence, OR 97439 ~21.49 miles north of Lake City
  • Cheap property
From$99
Average 3.0 /5 Reviews Call BookMore Details
Travelodge by Wyndham Florence : 3783a West Palmetto St.
+1-888-469-4795
3783a West Palmetto St., Florence, SC 29502 ~21.49 miles north of Lake City
  • Low Cost Highway property
  • Complimentary breakfast is offered
From$60
Not Good 1.0 /5 Guest Reviews Call BookMore Details
Comfort Inn & Suites Florence
+1-888-734-9421
527 Woody Jones Blvd., Sc 554, SC 29501 ~22.63 miles north of Lake City
  • 3-star Suburban property
  • Free breakfast
From$80
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Florence I-20
+1-888-841-5292
501 Woody Jones Blvd., Florence, SC 29501 ~22.66 miles north of Lake City
  • 3-star Convention Center hotel
  • 3 floors in property
From$99
Average 3.0 /5 Recent Reviews Call BookMore Details
Home2 Suites by Hilton Florence, SC : 900 Woody Jones Blvd.
+1-888-455-5160
900 Woody Jones Blvd., Florence, SC 29501 ~22.71 miles north of Lake City
  • Mid-scale Convention Center property
  • Comp. Breakfast
From$89
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Towneplace Suites by Marriott Florence in Florence
+1-888-965-8297
2650 Hospitality Blvd., Florence, SC 29501 ~22.79 miles north of Lake City
  • Mid-scale Suburban hotel
  • Fitness center on property
From$94
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Accident
+1-888-906-6358
Florence Sc Usa, Florence, SC 29464 ~22.83 miles north of Lake City
  • Midscale property
From$307
Average 3.0 /5 Read Reviews Call BookMore Details
Residence Inn Marriott Florence : 2660 Hospitality Blvd.
+1-888-749-6785
2660 Hospitality Blvd., Florence, SC 29501 ~22.85 miles north of Lake City
  • Mid-scale Suburban hotel
  • Check in time: 4:00 PM
From$94
Very Good 4.0 /5 Latest Reviews Call BookMore Details
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Staybridge Suites
+1-888-878-9982
150 Westpark Dr., Florence, SC 29501 ~22.87 miles north of Lake City
  • Three Star Convention Center hotel
  • Free breakfast available
From$133
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Ex Hotel & Suites Florence I-95 & I-20 Civic Ctr, an - Florence
+1-888-389-4485
3440 West Radio Dr., Florence, SC 29501 ~22.87 miles north of Lake City
  • Three Star Convention Center property
  • 23 suites in hotel
From$95
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Red Roof Inn Florence - Civic Center
+1-888-389-4121
2690 David Mcleod Blvd., Florence, SC 29501 ~22.89 miles north of Lake City
  • Luxurious 5-star Highway property
  • Check-in time: 1:00PM
From$61
Average 3.0 /5 Guest Reviews Call BookMore Details
Hyatt Place Florence Downtown
+1-888-675-2083
100 East Evans St., Florence, SC 29501 ~22.95 miles north of Lake City
  • Four star property
  • 101 rooms in hotel
From$160
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hyatt Place Florence Downtown
+1-800-716-8490
100 East Evans St., Florence, SC 29505 ~22.96 miles north of Lake City
  • Affordable Downtown property
  • Check in time: 3:00
From$124
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hotel Florence Tapestry Collection by Hilton
+1-800-805-5223
126 West Evans St., Florence, SC 29501 ~22.97 miles north of Lake City
  • Affordable Downtown property
  • Check in: 4:00pm
From$114
Very Good 4.0 /5 Reviews Call BookMore Details
Homewood Suites by Hilton Florence
+1-888-965-1860
3450 West Radio Dr., Florence, SC 29501 ~22.98 miles north of Lake City
  • Mid-scale Convention Center hotel
  • 22 suites in property
From$80
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Florence
+1-888-788-5576
2680 Hospitality Blvd., Florence, SC 29501 ~22.99 miles north of Lake City
  • 3 star Convention Center property
  • 90 rooms in property
From$99
Average 3.0 /5 Review Score Call BookMore Details
Springhill Suites by Marriott Florence : 2670 Hospitality Blvd.
+1-888-897-9207
2670 Hospitality Blvd., Florence, SC 29501 ~22.99 miles north of Lake City
  • Affordable Convention Center property
  • Hotel has 95 suites
From$89
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn
+1-888-311-4278
2671 Hospitality Blvd., Florence, SC 29501 ~23.00 miles north of Lake City
  • 3-star Highway hotel
  • 15 suites in hotel
From$109
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Florence Center : 3000 West Radio Dr.
+1-888-469-4795
3000 West Radio Dr., Florence, SC 29501 ~23.14 miles north of Lake City
  • Mid-scale Convention Center hotel
  • 21 suites in property
From$109
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Florence Near Civic Center in Florence
+1-888-734-9421
140 Dunbarton Dr., Florence, SC 29501 ~23.21 miles north of Lake City
  • Low priced Convention Center property
  • Check in: 3:00pm
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Rodeway Inn & Suites - Florence
+1-888-841-5292
181 West Lucas St., Florence, SC 29501 ~23.50 miles north of Lake City
  • Inexpensive property
  • Fitness center on property
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 An I : 2101 Florence Harllee Blvd.
+1-888-455-5160
2101 Florence Harllee Blvd., Florence, SC 29506 ~23.79 miles north of Lake City
  • 3 star Suburban property
  • Fitness / Gym is on-site
From$94
Very Good 4.0 /5 Review Score Call BookMore Details
Quality Inn And Suites Civic : 150 Dunbarton Dr.
+1-888-965-8297
150 Dunbarton Dr., Florence, SC 29501 Website ~23.88 miles north of Lake City
  • Two-star Highway property
  • 2 meeting rooms in hotel
From$79
Average 3.0 /5 Recent Reviews Call BookMore Details
Best Western Inn
+1-888-906-6358
1808 West Lucas St., Florence, SC 29501 ~25.09 miles north of Lake City
  • Three Star Downtown property
  • Free comp. breakfast
From$89
Average 3.0 /5 Recent Reviews Call BookMore Details
Baymont Inn & Suites Florence by Wyndham
+1-888-749-6785
1826 West Lucas St., Florence, SC 29501 ~25.11 miles north of Lake City
  • 2-star Highway property
  • 112 sleeping rooms in hotel
From$55
Poor 2.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Florence
+1-888-878-9982
1832 1 / 2 Lucas St., Florence, SC 29501 ~25.13 miles north of Lake City
  • Cheap Highway hotel
  • Check in: 11:00 AM
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Knights Inn Florence
+1-888-389-4485
1834 West Lucas St., Florence, SC 29501 ~25.17 miles north of Lake City
  • 2-star property
  • 109 sleeping rooms in hotel
From$50
Poor 2.0 /5 Reviews Call BookMore Details
Fairview Inn Florence
+1-888-389-4121
1811 West Lucas St., Florence, SC 29501 ~25.21 miles north of Lake City
  • Low-priced Highway hotel
  • 60 rooms in hotel
Mainstay Suites Florence Sc
+1-888-675-2083
1819 West Lucas St. Building B, Florence, SC 29501 ~25.33 miles north of Lake City
  • Economy Highway hotel
  • Hotel has 15 suites
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Clarion Inn & Suites - Florence
+1-800-716-8490
1819 Building a West Lucas St., Florence, SC 29501 ~25.33 miles north of Lake City
  • 3 star Highway hotel
  • Check-in time: 3:00
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 Florence, SC - Florence
+1-800-805-5223
2004 West Lucas St., Florence, SC 29501 ~25.36 miles north of Lake City
  • Cheap Downtown hotel
From$60
Average 3.0 /5 Review Score Call BookMore Details
Park Inn by Radisson Florence Sc in Florence
+1-888-965-1860
1729 Mandeville Rd., Florence, SC 27407 ~25.39 miles north of Lake City
  • Mid-scale hotel
  • Check in: 15:00
From$90
Very Good 4.0 /5 Read Reviews Call BookMore Details
Park Inn by Radisson in Florence
+1-888-788-5576
1729 Mandeville Rd., Florence, SC 29501 ~25.39 miles north of Lake City
  • Low Cost Highway property
  • Gym is available on property
From$75
Average 3.0 /5 Hotel Reviews Call BookMore Details
Country Inn & Suites by Radisson Florence Sc - Florence
+1-888-897-9207
1739 Mandeville Rd., Florence, SC 29501 ~25.43 miles north of Lake City
  • Affordable Highway property
  • 80 rooms in hotel
From$79
Very Good 4.0 /5 Read Reviews Call BookMore Details
Suburban Studios
+1-888-311-4278
1914 West Lucas St., Florence, SC 29501 ~25.48 miles north of Lake City
  • Low priced Highway property
  • Check-in time: 3:00 pm
Howard Johnson by Wyndham Florence in Florence
+1-888-469-4795
2038 West Lucas St., Florence, SC 29501 ~25.49 miles north of Lake City
  • Low-priced Highway hotel
  • 104 rooms in property
Hampton Inn & Suites Florence North
+1-888-734-9421
1735 Stokes Rd., Florence, SC 29501 ~25.50 miles north of Lake City
  • Low-priced Highway property
  • Free complimentary breakfast
From$104
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Florence/I-95 North - Florence
+1-888-841-5292
2111 West Lucas, Florence, SC 29501 ~25.61 miles north of Lake City
  • Inexpensive Highway property
  • 2 floors in hotel
From$50
Average 3.5 /5 Guest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Florence
+1-888-455-5160
2123 West Lucas St., Florence, SC 29501 ~25.61 miles north of Lake City
  • Three Star Highway property
  • Comp. Breakfast
From$82
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Suites Florence I-95 in Florence
+1-888-965-8297
2120 West Lucas St., Florence, SC 29501 ~25.65 miles north of Lake City
  • Midscale Highway property
  • Has environment-friendly policy See policy
From$80
Very Good 4.0 /5 Read Reviews Call BookMore Details
Tru by Hilton Florence I-95 - Florence
+1-888-906-6358
2140 West Lucas St., Florence, SC 29501 ~25.70 miles north of Lake City
  • 3-star hotel
  • Check-in time: 3:00pm
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Sleep Inn Florence - Florence
+1-888-749-6785
1833 Florence Park Dr., Florence, SC 29501 ~25.74 miles north of Lake City
  • Low Cost Highway hotel
  • Free breakfast available
From$59
Average 3.0 /5 Review Score Call BookMore Details
Microtel Inn & Suites by Wyndham Florence : 1912 Enterprise Dr.
+1-888-878-9982
1912 Enterprise Dr., Florence, SC 29501 ~25.82 miles north of Lake City
  • Economical property
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details

Next: See My Lake City Hotels with Pricing

Graph: Next 20 Days of Lake City Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Lake City, SC discounts available. The chart reflects the cheapest Lake City hotel for each day and each star rating category.

FAQs about hotels in Lake City

What are the most favored hotels in Lake City?

Comfort Inn & Suites Florence, Homewood Suites by Hilton Florence and Inn at the Crossroads are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels in Lake City?

Red Roof Inn Florence - Civic Center, Hyatt Place Florence Downtown and Quality Inn & Suites are the top 3 luxury hotels near Lake City city center.

What hotels are closest to the city center of Lake City?

Inn at the Crossroads, Days Inn by Wyndham Lake City, and Quality Inn & Suites are the properties closest to Lake City city center.

How much does a cheap hotel in Lake City cost per night?

In the last year, a 2 star hotel in Lake City can be as cheap as $47.48 per night. (based on HotelPlanner prices)

How much does a 3 star hotel in Lake City cost per night?

In the last year, the average 3 star hotel in Lake City has been $64.50 per night. (based on HotelPlanner prices)

What are the best independent hotels in Lake City?

Inn at the Crossroads, Fairview Inn Florence and Suburban Studios are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Lake City?

Towneplace Suites by Marriott Florence, Residence Inn Marriott Florence and Springhill Suites by Marriott Florence are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels in Lake City?

Comfort Inn & Suites Florence, Quality Inn & Suites and Quality Inn are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Lake City?

Staybridge Suites, Holiday Inn Ex Hotel & Suites Florence I-95 & I-20 Civic Ctr, an and Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 An I are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Recent traveler reviews of Lake City, SC

Below are reviews of the city of Lake City, SC from an actual visitor's perspective.

"Convenient Location"
Score 4.0 / 5

Everywhere was convenient to hotel.

Ishmal S., from 12-Jul-2023
"Great, Emerging City"
Score 4.0 / 5

The town has grown since the last time I visited. The shops were within walking distance. Every place we visited was very nice.

Cheryl H., from 10-Nov-2014
The average traveler rating of the city of Lake City, SC shown above is 4.0 out of 5 based on 2 reviews
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