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Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles west of Lake Marion Resort and Marina and 18 miles east of Edisto Memorial Gardens.

Santee Hotels/Accommodations

Days Inn in Santee 9074 Old Highway Six, Santee, SC 29142
  • Low-priced hotel
Holiday Inn Santee : 139 Bradford Blvd. 139 Bradford Blvd., Santee, SC 29142
  • Mid-scale Highway hotel
  • 84 sleeping rooms in hotel
Comfort Inn & Suites 221 Britain St., Santee, SC 29142
  • Cheap Lake property
  • 20 suites in hotel
Red Roof Inn : 9091 Old No 6 Highway 9091 Old No 6 Highway, Santee, SC 29142
  • Economical Golf Course property
  • Check-in time: 1.00
Quality Inn & Suites : 8929 Bass Dr.
+1-866-221-8581
8929 Bass Dr., Santee, SC 29142
  • Two-star Golf Course property
  • Check in time: 3:00PM
Knights Inn Santee : 249 Britain St. 249 Britain St., Santee, SC 29142
  • Cheap Highway hotel
  • 2 suites in property
Clarion Inn in Santee
+1-888-690-5281
123 Mall St., Santee, SC 29142
  • Mid-scale Highway hotel
  • Fitness + Health Center
  • Conventional furniture
  • Hair dryer didn't work
Hampton Inn Santee I 95 in Santee 9060 Old #6 Highway, Santee, SC 29142
  • 3-star Highway property
  • 81 sleeping rooms in hotel
  • Excellent pool
  • Great reception
From$91
Very Good 4.5 /5Read Reviews CallBookMore Details
Super 8 by Wyndham Santee 9125 Old Highway 6, Santee, SC 29142
  • 2 star property
From$60
Average 3.5 /5Reviews CallBookMore Details
Best Western Plus Santee Inn I 95 Exit 98, Santee, SC 29142
  • 2-star hotel
  • 102 rooms in hotel
Econo Lodge
+1-888-283-3404
9112 Old Number 6 Highway, Santee, SC 29142
  • 2-star Highway property
  • Check in: 11:00
  • Furniture needs more attention
  • Pillows were old
Rodeway Inn 9117 Old Number 6 Highway, Santee, SC 29142
  • 2-star Highway property
  • Check-in: 11:00
Days Inn Summerton : 400 Buff Blvd. 400 Buff Blvd., Summerton, SC 29148 ~10.34 miles northeast of Santee
  • 2-star property
  • Check-in time: 11:00 AM
Americas Best Value Inn
+1-888-690-5281
401 Buff Blvd., Columbia, SC 29148 ~11.09 miles northeast of Santee
  • 2-star hotel
Days Inn Orangeburg South - Orangeburg 3402 Five Chop Rd., Orangeburg, SC 29115 ~14.02 miles west of Santee
  • Low priced Highway hotel
  • 95 rooms in property
From$60
Average 3.0 /5Reviews CallBookMore Details
Peachtree Inn : 111 Conners Dr. 111 Conners Dr., Saint George, SC 29477 ~15.51 miles south of Santee
  • Three Star Highway property
  • 2 floors in hotel
Knights Inn Manning Sc 6137 Alex Harvin Highway, Manning, SC 29102 ~16.15 miles northeast of Santee
  • Two-star hotel
  • Hotel has 58 rooms
Sunset Inn Manning
+1-888-283-3404
5932 Alex Highway, Manning, SC 29102 ~16.27 miles northeast of Santee
  • 2-star hotel
Hampton Inn 2822 Paxville Highway, Manning, SC 29102 ~19.30 miles northeast of Santee
  • 3 star Highway hotel
  • Access to gym on-site
Quality Inn 3031 Paxville Highway, Manning, SC 29102 ~19.32 miles northeast of Santee
  • Economy Golf Course hotel
  • Hotel has 60 rooms
  • Not very comfortable
  • Rooms are not good
Fairfield Inn Orangeburg 663 Citadel Rd., Orangeburg, SC 29118 Website ~20.26 miles west of Santee
  • Midscale Highway property
  • Free breakfast available
  • Older building
  • Rooms are ok
Country Inns & Suites Orangeburg - Orangeburg 731 Citadel Rd., Orangeburg, SC 29118 ~20.37 miles west of Santee
  • Midscale Highway hotel
  • Hotel has an eco-friendly policy See more
From$103
Very Good 4.0 /5Hotel Reviews CallBookMore Details
Comfort Inn & Suites 746 Citadel Rd., Orangeburg, SC 29118 ~20.37 miles west of Santee
  • Low priced Rural hotel
  • Hotel has 3 floors
  • Most guests were happy with the price of the breakfast
  • Fair breakfast prices
Hampton Inn & Suites Orangeburg : 749 Citadel Rd. 749 Citadel Rd., Orangeburg, SC 29118 ~20.42 miles west of Santee
  • Three Star Highway hotel
  • 90 rooms in property
From$119
Very Good 4.5 /5Latest Reviews CallBookMore Details
Days Inn
+1-888-283-3404
2825 Paxville Highway, Manning, SC 29102 ~20.47 miles northeast of Santee
  • Cheap property
  • 2 floors in property
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