Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles from Lake Marion Resort and Marina and 18 miles from Edisto Memorial Gardens.

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Santee Hotels/Motels & Accommodations

Days Inn in Santee
+1-800-230-4134
$35+

9074 Old Highway Six, Santee, SC 29142
  • Cheap hotel
Image of Holiday Inn SanteeHoliday Inn Santee in Santee
+1-800-997-5148
$93+

139 Bradford Blvd., Santee, SC 29142
  • 3.0/5, Average Reviews
  • 3 star Highway property
  • Hotel has 84 rooms
Image of Comfort Inn & SuitesComfort Inn & Suites - Santee
+1-800-997-5149
$80+

221 Britain St., Santee, SC 29142
  • 4.0/5, Very Good Read Reviews
  • 2 star Lake property
  • Free complimentary breakfast
Image of Quality Inn & SuitesQuality Inn & Suites
+1-800-230-4134
$72+

8929 Old Number Six Highway, Santee, SC 29142
  • 3.0/5, Average Reviews
  • Low Cost Highway hotel
  • Free breakfast available
Exterior of Howard Johnson SanteeHoward Johnson Santee : 249 Britain St.
+1-800-997-5148
$40+

249 Britain St., Santee, SC 29142
  • 3.0/5, Average Latest Reviews
  • Economical Golf Course property
  • Check-in time: 03:00pm
Image of Whitten InnWhitten Inn - Santee
+1-800-997-5149
$54+

123 Mall St., Santee, SC 29142
Hampton Inn Santee I 95 : 9060 Old #6 Highway
+1-800-230-4134
$89+

9060 Old #6 Highway, Santee, SC 29142
  • 4.5/5, Very Good Latest Reviews
  • 3 star Highway hotel
  • Check-in time: 3:00 pm
Image of Rodeway Inn SanteeRodeway Inn Santee : 9117 Old Number 6 Highway
+1-800-997-5148
$29+

9117 Old Number 6 Highway, Santee, SC 29142
  • 3.0/5, Average Read Reviews
  • Two star Highway property
  • Check in: 02:00 PM
Best Western Plus Santee Inn in Santee
+1-800-997-5149
$88+

9059 Old Number Six Highway, Santee, SC 29142
  • Affordable hotel
Travelodge : 9091 Old Highway 6
+1-800-230-4134
$75+

9091 Old Highway 6, Santee, SC 29142
  • 2.5/5, Poor Reviews
  • Low Cost Golf Course hotel
  • Check in time: 1.00
Econo Lodge in Santee
+1-800-997-5148
$75+

9112 Old Number 6 Hww., Santee, SC 29142
  • 2 star Highway property
  • Check in: 02:00 PM
Peachtree Inn
+1-800-997-5149
$49+

111 Conners Dr., Saint George, SC 29477
  • 4.5/5, Very Good Recent Reviews
  • 3 star Highway property
  • Check-in time: 3.00
~15.51 Miles from Santee
Sunset Inn Manning - Manning
+1-800-230-4134
$50+

5932 Alex Highway, Manning, SC 29102~16.27 Miles from Santee
Hampton Inn in Manning
+1-800-997-5148
$80+

2822 Paxville Highway, Manning, SC 29102
  • 4.5/5, Very Good Reviews
  • 3-star Highway property
  • Free breakfast
~19.30 Miles from Santee
Quality Inn
+1-800-997-5149
$57+

3031 Paxville Highway, Manning, SC 29102~19.32 Miles from Santee
Country Inn & Suites
+1-800-230-4134
$94+

731 Citadel Rd., Orangeburg, SC 29118
  • 3.5/5, Average Hotel Reviews
  • Low Cost property
  • Free comp. breakfast
~19.66 Miles from Santee
Fairfield Inn Orangeburg
+1-800-997-5148
$90+

663 Citadel, Orangeburg, SC 29118
  • 3.5/5, Average Guest Reviews
  • Three Star property
  • 3 floors in property
~20.28 Miles from Santee
Comfort Inn & Suites - Orangeburg
+1-800-997-5149
$89+

746 Citadel Rd., Orangeburg, SC 29118
  • 4.0/5, Very Good Review Score
  • 2-star Rural property
  • 69 rooms in property
~20.37 Miles from Santee
Days Inn - Manning
+1-800-230-4134
$63+

2825 Paxville Highway, Manning, SC 29102~20.47 Miles from Santee
Exterior of Southern LodgeSouthern Lodge
+1-800-997-5148
$58+

3616 St. Matthews Rd., Orangeburg, SC 29118 Website
  • Two star Highway property
  • Hotel has 43 rooms
~20.48 Miles from Santee

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