Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts


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Santee Hotels & Accommodations

Days Inn
+1-800-230-4134
$35+

9074 Old Highway Six, Santee, SC 29142
  • Two-star property
Photo of Holiday Inn SanteeHoliday Inn Santee
+1-800-997-5148
$93+

139 Bradford Blvd., Santee, SC 29142
Image of Comfort Inn & SuitesComfort Inn & Suites
+1-800-997-5149
$129+

221 Britain St., Santee, SC 29142
  • 3.5/5, Average Recent Reviews
  • Economical Lake hotel
  • Gym is available on property
Image of Quality Inn & SuitesQuality Inn & Suites
+1-800-230-4134
$72+

8929 Old Number Six Highway, Santee, SC 29142
  • 3.0/5, Average Read Reviews
  • Two star Highway property
  • Check-in time: 3:00PM
Exterior of Howard Johnson SanteeHoward Johnson Santee : 249 Britain St.
+1-800-997-5148
$40+

249 Britain St., Santee, SC 29142
  • 3.0/5, Average Guest Reviews
  • Low-priced Golf Course property
  • Comp. Breakfast
Exterior of Whitten InnWhitten Inn : 123 Mall St.
+1-800-997-5149
$54+

123 Mall St., Santee, SC 29142
  • 2.5/5, Poor Read Reviews
  • Low-priced Highway property
  • Free comp. breakfast
Hampton Inn Santee I 95 in Santee
+1-800-230-4134
$89+

9060 Old #6 Highway, Santee, SC 29142
  • 4.5/5, Very Good Read Reviews
  • Midscale Highway hotel
  • 7 suites in hotel
Best Western Plus Santee Inn
+1-800-997-5148
$88+

9059 Old Number Six Highway, Santee, SC 29142
  • 3 star property
Rodeway Inn Santee in Santee
+1-800-997-5149
$29+

9117 Old Number 6 Highway, Santee, SC 29142
  • 3.0/5, Average Read Reviews
  • Two star Highway hotel
  • Check-in: 02:00 PM
Travelodge in Santee
+1-800-230-4134
$75+

9091 Old Highway 6, Santee, SC 29142
  • 3.5/5, Average Hotel Reviews
  • Two star Golf Course hotel
  • Check-in time: 1.00
Econo Lodge
+1-800-997-5148
$75+

9112 Old Number 6 Hww., Santee, SC 29142
  • Two-star Highway hotel
  • Free breakfast
Peachtree Inn
+1-800-997-5149
$49+

111 Conners Dr., Saint George, SC 29477
  • 4.5/5, Very Good Reviews
  • Midscale Highway hotel
  • 39 sleeping rooms in hotel
~15.51 Miles from Santee
Sunset Inn Manning
+1-800-230-4134
$50+

5932 Alex Highway, Manning, SC 29102~16.27 Miles from Santee
Hampton Inn : 2822 Paxville Highway
+1-800-997-5148
$80+

2822 Paxville Highway, Manning, SC 29102
  • 4.5/5, Very Good Read Reviews
  • Affordable Highway property
  • 73 rooms in hotel
~19.30 Miles from Santee
Quality Inn in Manning
+1-800-997-5149
$57+

3031 Paxville Highway, Manning, SC 29102~19.32 Miles from Santee
Country Inn & Suites - Orangeburg
+1-800-230-4134
$94+

731 Citadel Rd., Orangeburg, SC 29118
  • 3.5/5, Average Read Reviews
  • Low Cost property
  • 81 rooms in property
~19.66 Miles from Santee
Fairfield Inn Orangeburg : 663 Citadel
+1-800-997-5148
$90+

663 Citadel, Orangeburg, SC 29118
  • 3.5/5, Average Reviews
  • 3-star hotel
  • 60 sleeping rooms in hotel
~20.28 Miles from Santee
Comfort Inn & Suites
+1-800-997-5149
$89+

746 Citadel Rd., Orangeburg, SC 29118
  • 4.0/5, Very Good Recent Reviews
  • Low Cost Rural property
  • Hotel has 14 suites
~20.37 Miles from Santee
Days Inn - Manning
+1-800-230-4134
$63+

2825 Paxville Highway, Manning, SC 29102~20.47 Miles from Santee
Exterior of Southern LodgeSouthern Lodge - Orangeburg
+1-800-997-5148
$58+

3616 St. Matthews Rd., Orangeburg, SC 29118 Website
  • Economy Highway hotel
  • Check-in: 2.00pm
~20.48 Miles from Santee

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