Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles from Lake Marion Resort and Marina and 18 miles from Edisto Memorial Gardens.

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Santee Hotels & Accommodations

Days Inn - Santee
+1-800-230-4134Check Rates
9074 Old Highway Six, Santee, SC 29142
  • Inexpensive hotel
Photo of Holiday Inn SanteeHoliday Inn Santee - Santee
+1-800-997-5148Check Rates
139 Bradford Blvd., Santee, SC 29142
  • 3.0/5, Average Hotel Reviews
  • Midscale Highway property
  • Hotel has 84 rooms
Photo of Comfort Inn & SuitesComfort Inn & Suites
+1-800-997-5149Check Rates
221 Britain St., Santee, SC 29142
  • 3.5/5, Average Read Reviews
  • Low Cost Lake hotel
  • Fitness / Gym is on-site
Image of Quality Inn & SuitesQuality Inn & Suites - Santee
+1-800-230-4134Check Rates
8929 Old Number Six Highway, Santee, SC 29142
  • 3.0/5, Average Hotel Reviews
  • Cheap Highway property
  • 2 meeting rooms in property
Exterior of Howard Johnson SanteeHoward Johnson Santee
+1-800-997-5148Check Rates
249 Britain St., Santee, SC 29142
  • 3.0/5, Average Guest Reviews
  • Inexpensive Golf Course hotel
  • 60 rooms in hotel
Exterior of Whitten InnWhitten Inn
+1-800-997-5149Check Rates
123 Mall St., Santee, SC 29142
  • 2.5/5, Poor Latest Reviews
  • Economy Highway hotel
  • 3 conference rooms in property
Hampton Inn Santee I 95
+1-800-230-4134Check Rates
9060 Old #6 Highway, Santee, SC 29142
  • 4.5/5, Very Good Reviews
  • Affordable Highway hotel
  • Free complimentary breakfast
Exterior of Rodeway Inn SanteeRodeway Inn Santee in Santee
+1-800-997-5148Check Rates
9117 Old Number 6 Highway, Santee, SC 29142
  • 3.0/5, Average Latest Reviews
  • Inexpensive Highway property
  • Free breakfast available
Best Western Plus Santee Inn in Santee
+1-800-997-5149Check Rates
9059 Old Number Six Highway, Santee, SC 29142
  • Three Star hotel
Travelodge
+1-800-230-4134Check Rates
9091 Old Highway 6, Santee, SC 29142
  • 2.5/5, Poor Guest Reviews
  • Low-priced Golf Course property
  • 40 rooms in property
Econo Lodge : 9112 Old Number 6 Hww.
+1-800-997-5148Check Rates
9112 Old Number 6 Hww., Santee, SC 29142
  • Low Cost Highway hotel
  • Check-in time: 02:00 PM
Peachtree Inn
+1-800-997-5149Check Rates
111 Conners Dr., Saint George, SC 29477
  • 4.5/5, Very Good Recent Reviews
  • Three Star Highway property
  • Check in time: 3.00
~15.51 Miles from Santee
Sunset Inn Manning
+1-800-230-4134Check Rates
5932 Alex Highway, Manning, SC 29102~16.27 Miles from Santee
Hampton Inn : 2822 Paxville Highway
+1-800-997-5148Check Rates
2822 Paxville Highway, Manning, SC 29102
  • 4.5/5, Very Good Hotel Reviews
  • Affordable Highway hotel
  • 3 floors in property
~19.30 Miles from Santee
Quality Inn : 3031 Paxville Highway
+1-800-997-5149Check Rates
3031 Paxville Highway, Manning, SC 29102~19.32 Miles from Santee
Country Inn & Suites : 731 Citadel Rd.
+1-800-230-4134Check Rates
731 Citadel Rd., Orangeburg, SC 29118~19.66 Miles from Santee
Fairfield Inn Orangeburg : 663 Citadel
+1-800-997-5148Check Rates
663 Citadel, Orangeburg, SC 29118~20.28 Miles from Santee
Comfort Inn & Suites - Orangeburg
+1-800-997-5149Check Rates
746 Citadel Rd., Orangeburg, SC 29118
  • 4.0/5, Very Good Recent Reviews
  • 2 star Rural property
  • Gym is available on property
~20.37 Miles from Santee
Days Inn - Manning
+1-800-230-4134Check Rates
2825 Paxville Highway, Manning, SC 29102~20.47 Miles from Santee
Photo of Southern LodgeSouthern Lodge
+1-800-997-5148Check Rates
3616 St. Matthews Rd., Orangeburg, SC 29118 Website
  • Cheap Highway hotel
~20.48 Miles from Santee

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