Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts


Find my perfect hotel Rooms Check-In Check-Out  
Show Calendar Show Calendar Start My Search >
(select the discounts you qualify for)
Star Rating




Hotel Name

Price Range (USD)
to
Amenities







Set My Filter

Santee Hotels/Motels & Accommodations

Days Inn
+1-800-230-4134
$35+

9074 Old Highway Six, Santee, SC 29142
  • 2 star property
Photo of Holiday Inn SanteeHoliday Inn Santee - Santee
+1-800-997-5148
$93+

139 Bradford Blvd., Santee, SC 29142
Photo of Comfort Inn & SuitesComfort Inn & Suites - Santee
+1-800-997-5149
$80+

221 Britain St., Santee, SC 29142
Exterior of Quality Inn & SuitesQuality Inn & Suites - Santee
+1-800-230-4134
$72+

8929 Old Number Six Highway, Santee, SC 29142
  • 3.0/5, Average Recent Reviews
  • Economy Highway property
  • 153 rooms in hotel
Photo of Howard Johnson SanteeHoward Johnson Santee - Santee
+1-800-997-5148
$40+

249 Britain St., Santee, SC 29142
  • 3.0/5, Average Reviews
  • Low-priced Golf Course hotel
  • Free complimentary breakfast
Image of Whitten InnWhitten Inn in Santee
+1-800-997-5149
$54+

123 Mall St., Santee, SC 29142
  • 2.5/5, Poor Guest Reviews
  • Cheap Highway hotel
  • Check in time: 2:00 pm
Hampton Inn Santee I 95
+1-800-230-4134
$89+

9060 Old #6 Highway, Santee, SC 29142
Image of Rodeway Inn SanteeRodeway Inn Santee
+1-800-997-5148
$29+

9117 Old Number 6 Highway, Santee, SC 29142
  • 3.0/5, Average Reviews
  • Inexpensive Highway hotel
  • Free breakfast
Best Western Plus Santee Inn : 9059 Old Number Six Highway
+1-800-997-5149
$88+

9059 Old Number Six Highway, Santee, SC 29142
  • 3-star property
Travelodge
+1-800-230-4134
$75+

9091 Old Highway 6, Santee, SC 29142
  • 3.5/5, Average Reviews
  • Two star Golf Course hotel
  • Hotel has 40 rooms
Econo Lodge in Santee
+1-800-997-5148
$75+

9112 Old Number 6 Hww., Santee, SC 29142
  • Economical Highway property
  • Free breakfast
Peachtree Inn
+1-800-997-5149
$49+

111 Conners Dr., Saint George, SC 29477
  • 4.5/5, Very Good Review Score
  • Midscale Highway hotel
  • 39 sleeping rooms in hotel
~15.51 Miles from Santee
Sunset Inn Manning : 5932 Alex Highway
+1-800-230-4134
$50+

5932 Alex Highway, Manning, SC 29102~16.27 Miles from Santee
Hampton Inn
+1-800-997-5148
$80+

2822 Paxville Highway, Manning, SC 29102
  • 4.5/5, Very Good Hotel Reviews
  • Midscale Highway hotel
  • Fitness + Health Center
~19.30 Miles from Santee
Quality Inn in Manning
+1-800-997-5149
$57+

3031 Paxville Highway, Manning, SC 29102~19.32 Miles from Santee
Country Inn & Suites
+1-800-230-4134
$94+

731 Citadel Rd., Orangeburg, SC 29118~19.66 Miles from Santee
Fairfield Inn Orangeburg - Orangeburg
+1-800-997-5148
$90+

663 Citadel, Orangeburg, SC 29118~20.28 Miles from Santee
Comfort Inn & Suites in Orangeburg
+1-800-997-5149
$89+

746 Citadel Rd., Orangeburg, SC 29118
  • 4.0/5, Very Good Hotel Reviews
  • Cheap Rural property
  • Hotel has 69 rooms
~20.37 Miles from Santee
Days Inn : 2825 Paxville Highway
+1-800-230-4134
$63+

2825 Paxville Highway, Manning, SC 29102~20.47 Miles from Santee
Photo of Southern LodgeSouthern Lodge
+1-800-997-5148
$58+

3616 St. Matthews Rd., Orangeburg, SC 29118 Website
  • Inexpensive Highway property
  • Check in: 2.00pm
~20.48 Miles from Santee

 [1 - 20 of 50]   


Next: See My Santee Hotels with Pricing >