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Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles west of Lake Marion Resort and Marina and 18 miles east of Edisto Memorial Gardens.

Santee Hotels & Accommodations

Days Inn 9074 Old Highway Six, Santee, SC 29142
  • Low-priced property
Holiday Inn Santee 139 Bradford Blvd., Santee, SC 29142
  • 3 star Highway hotel
  • Gym is available on property
Comfort Inn & Suites 221 Britain St., Santee, SC 29142
  • Two-star Lake hotel
  • Gym is available on property
  • Average cleanliness
  • Most guests found the staff to be very friendly
Quality Inn & Suites in Santee
+1-888-283-3404
8929 Old Number Six Highway, Santee, SC 29142
  • Low Cost Highway hotel
  • Complimentary breakfast is offered
Howard Johnson in Santee 249 Britain St., Santee, SC 29142
  • Cheap Golf Course property
  • Comp. Breakfast
Red Roof Inn : 9091 Old No 6 Highway 9091 Old No 6 Highway, Santee, SC 29142
  • 2-star Golf Course hotel
  • 40 sleeping rooms in hotel
Whitten Inn - Santee
+1-888-690-5281
123 Mall St., Santee, SC 29142
  • Low-priced Highway hotel
  • Hotel has 2 floors
Hampton Inn Santee I 95 : 9060 Old #6 Highway 9060 Old #6 Highway, Santee, SC 29142
  • Three Star Highway property
  • Hotel has 3 floors
  • Bathroom could be optimized
  • Clean
From$90
Very Good 4.5 /5Review Score CallBookMore Details
Best Western Plus Santee Inn I 95 Exit 98, Santee, SC 29142
  • 3-star property
  • Hotel has 102 rooms
From$80
Very Good 4.5 /5Reviews CallBookMore Details
Econo Lodge 9112 Old Number 6 Highway, Santee, SC 29142
  • Economy Highway hotel
  • Hotel has 37 rooms
Rodeway Inn in Santee 9117 Old Number 6 Highway, Santee, SC 29142
  • Low Cost Highway hotel
  • Check-in time: 11:00
Days Inn Summerton 400 Buff Blvd., Summerton, SC 29148 ~10.34 miles northeast of Santee
  • Low priced hotel
  • Check in time: 11:00 AM
Americas Best Value Inn in Columbia
+1-866-429-5787
401 Buff Blvd., Columbia, SC 29148 ~11.09 miles northeast of Santee
  • Inexpensive property
  • Check in: 15:00
Days Inn Orangeburg South : 3402 Five Chop Rd. 3402 Five Chop Rd., Orangeburg, SC 29115 ~14.02 miles west of Santee
  • Low-priced Highway hotel
  • Check-in time: 2pm
Peachtree Inn 111 Conners Dr., Saint George, SC 29477 ~15.51 miles south of Santee
  • Affordable Highway hotel
  • Check in time: 3.00
From$49
Very Good 4.0 /5Review Score CallBookMore Details
Knights Inn Manning Sc - Manning 6137 Alex Harvin Highway, Manning, SC 29102 ~16.15 miles northeast of Santee
  • Economical hotel
  • Hotel has 58 rooms
Sunset Inn Manning
+1-800-881-1523
5932 Alex Highway, Manning, SC 29102 ~16.27 miles northeast of Santee
  • Low Cost property
Hampton Inn 2822 Paxville Highway, Manning, SC 29102 ~19.30 miles northeast of Santee
  • Three Star Highway property
  • Check in time: 2:00pm
Quality Inn 3031 Paxville Highway, Manning, SC 29102 ~19.32 miles northeast of Santee
  • Low Cost Golf Course hotel
  • Check-in: 2:00 pm
  • Poor, uncomfortable rooms
  • Fantastic service
Fairfield Inn Orangeburg in Orangeburg 663 Citadel Rd., Orangeburg, SC 29118 ~20.26 miles west of Santee
  • 3-star Highway property
  • Fitness / Gym is on-site
  • Great reception
  • Good continental breakfast
From$101
Very Good 4.0 /5Read Reviews CallBookMore Details
Country Inn & Suites Orangeburg - Orangeburg 731 Citadel Rd., Orangeburg, SC 29118 ~20.37 miles west of Santee
  • Cheap Highway property
  • Check-in: 3:00 pm
Comfort Inn & Suites 746 Citadel Rd., Orangeburg, SC 29118 ~20.37 miles west of Santee
  • Two star Rural property
  • Gym is available on property
  • Fantastic service
  • Most guests said rooms were clean
Hampton Inn & Suites Orangeburg 749 Citadel Rd., Orangeburg, SC 29118 ~20.42 miles west of Santee
  • 3-star Highway hotel
  • 90 rooms in property
From$124
Very Good 4.5 /5Review Score CallBookMore Details
Days Inn
+1-800-881-1523
2825 Paxville Highway, Manning, SC 29102 ~20.47 miles northeast of Santee
  • Economical hotel
Southern Lodge : 3616 St. Matthews Rd. 3616 St. Matthews Rd., Orangeburg, SC 29118 ~20.48 miles west of Santee
  • Inexpensive Highway property
  • 43 rooms in property
  • Poorly cleaned rooms with uncomfortable furniture
  • Most guests thought the tv was sub-standard
From$39
Very Good 4.0 /5Reviews CallBookMore Details
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