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Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles west of Lake Marion Resort and Marina and 18 miles east of Edisto Memorial Gardens.

Santee Hotels/Accommodations

Days Inn 9074 Old Highway Six, Santee, SC 29142
  • Low Cost property
Holiday Inn Santee : 139 Bradford Blvd. 139 Bradford Blvd., Santee, SC 29142
  • Midscale Highway property
  • Gym / Fitness Center Available
Comfort Inn & Suites : 221 Britain St. 221 Britain St., Santee, SC 29142
  • Low-priced Lake property
  • Hotel has 20 suites
  • Room is all right
  • Copious breakfast
Quality Inn & Suites
+1-888-283-3404
8929 Old Number Six Highway, Santee, SC 29142
  • Two-star Highway hotel
  • 153 rooms in hotel
Howard Johnson : 249 Britain St. 249 Britain St., Santee, SC 29142
  • Low priced Golf Course hotel
  • Free breakfast available
Red Roof Inn - Santee 9091 Old No 6 Highway, Santee, SC 29142
  • Low priced Golf Course property
  • Check in: 1.00
Whitten Inn
+1-888-690-5281
123 Mall St., Santee, SC 29142
  • Inexpensive Highway hotel
  • Check in: 2:00 pm
Hampton Inn Santee I 95 9060 Old #6 Highway, Santee, SC 29142
  • Midscale Highway property
  • 81 rooms in hotel
  • Most guests said the reception staff was great
  • All facilities including
Best Western Plus Santee Inn I 95 Exit 98, Santee, SC 29142
  • Midscale hotel
  • Comp. Breakfast
Econo Lodge - Santee 9112 Old Number 6 Highway, Santee, SC 29142
  • Economy Highway hotel
  • Check-in time: 11:00
Rodeway Inn 9117 Old Number 6 Highway, Santee, SC 29142
  • Two star Highway hotel
  • Complimentary breakfast is offered
Days Inn Summerton 400 Buff Blvd., Summerton, SC 29148 ~10.34 miles northeast of Santee
  • Low Cost property
Americas Best Value Inn in Columbia
+1-866-429-5787
401 Buff Blvd., Columbia, SC 29148 ~11.09 miles northeast of Santee
  • Two-star hotel
  • 80 sleeping rooms in hotel
Days Inn Orangeburg South - Orangeburg 3402 Five Chop Rd., Orangeburg, SC 29115 ~14.02 miles west of Santee
  • Low-priced Highway property
  • 95 sleeping rooms in hotel
From$60
Average 3.0 /5Reviews CallBookMore Details
Peachtree Inn 111 Conners Dr., Saint George, SC 29477 ~15.51 miles south of Santee
  • Midscale Highway property
  • 2 floors in property
Knights Inn Manning Sc : 6137 Alex Harvin Highway 6137 Alex Harvin Highway, Manning, SC 29102 ~16.15 miles northeast of Santee
  • Two star property
  • 2 floors in hotel
Sunset Inn Manning in Manning
+1-800-881-1523
5932 Alex Highway, Manning, SC 29102 ~16.27 miles northeast of Santee
  • Low-priced hotel
Hampton Inn - Manning 2822 Paxville Highway, Manning, SC 29102 ~19.30 miles northeast of Santee
  • Affordable Highway hotel
  • Free breakfast
Quality Inn in Manning 3031 Paxville Highway, Manning, SC 29102 ~19.32 miles northeast of Santee
  • Economy Golf Course hotel
  • Hotel has 2 floors
  • Air conditioning did not work
  • Average beds
Fairfield Inn Orangeburg : 663 Citadel Rd. 663 Citadel Rd., Orangeburg, SC 29118 ~20.26 miles west of Santee
  • Mid-scale Highway hotel
  • Hotel has 64 rooms
  • Generally very clean
  • Comfortable
From$103
Very Good 4.0 /5Latest Reviews CallBookMore Details
Country Inn & Suites Orangeburg - Orangeburg 731 Citadel Rd., Orangeburg, SC 29118 ~20.37 miles west of Santee
  • 2-star hotel
  • 4 floors in hotel
Comfort Inn & Suites - Orangeburg 746 Citadel Rd., Orangeburg, SC 29118 ~20.37 miles west of Santee
  • Cheap Rural hotel
  • Hotel has 14 suites
  • Most guests were happy with the price of the breakfast
  • Spacious rooms
Hampton Inn & Suites Orangeburg : 749 Citadel Rd. 749 Citadel Rd., Orangeburg, SC 29118 ~20.42 miles west of Santee
  • Affordable Highway property
  • 32 suites in hotel
From$124
Very Good 4.5 /5Reviews CallBookMore Details
Days Inn
+1-800-881-1523
2825 Paxville Highway, Manning, SC 29102 ~20.47 miles northeast of Santee
  • Economical property
Southern Lodge : 3616 St. Matthews Rd. 3616 St. Matthews Rd., Orangeburg, SC 29118 ~20.48 miles west of Santee
  • Economical Highway hotel
  • Hotel has 43 rooms
  • Remote control not working
  • Most guests thought the tv was sub-standard
From$49
Very Good 4.0 /5Reviews CallBookMore Details
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