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Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles west of Lake Marion Resort and Marina and 18 miles east of Edisto Memorial Gardens.

The town of Santee, South Carolina, may be small, but it's big on Southern charm. More than 100,000 visitors come to Santee each year for some of the best fishing and golfing around. Easily accessed by Interstate 95, Santee is centrally located between two major cities. The state capital, Columbia, is one hour north, and the port city of Charleston is one hour south. More from this guide...

Santee Hotels/Motels & Accommodations

Holiday Inn Santee : 139 Bradford Blvd.
+1-888-690-5247
139 Bradford Blvd., Santee, SC 29142
  • 3-star Highway property
  • Fitness / Gym is on-site
Comfort Inn & Suites in Santee
+1-888-305-3366
221 Britain St., Santee, SC 29142
  • 2 star Lake property
  • Complimentary breakfast is offered
From$79
Average 3.5 /5Reviews CallBookMore Details
Red Roof Inn : 9091 Old No 6 Highway
+1-800-881-1523
9091 Old No 6 Highway, Santee, SC 29142
  • Low Cost Golf Course hotel
  • 40 rooms in hotel
Quality Inn & Suites
+1-888-283-3404
8929 Bass Dr., Santee, SC 29142
  • Low priced Golf Course hotel
  • 3 conference rooms in property
Knights Inn Santee : 249 Britain St.
+1-866-221-8581
249 Britain St., Santee, SC 29142
  • Low Cost Highway hotel
  • Hotel has 2 floors
Clarion Inn Santee I 95 - Santee
+1-866-429-5787
123 Mall St., Santee, SC 29142
  • 2 star Highway property
  • 2 floors in hotel
  • Dirty carpet
  • Hotel could use some updating
Hampton Inn Santee I 95 : 9060 Old #6 Highway
+1-888-690-5281
9060 Old #6 Highway, Santee, SC 29142
  • Three Star Highway property
  • Free comp. breakfast
  • Most guests thought it was clean
  • Most guests thought the service was very professional
Fairfield Inn & Suites by Marriott : 9074 Old Highway Number Six Highway
+1-888-690-5247
9074 Old Highway Number Six Highway, Santee, SC 29142
  • 3 star Highway hotel
  • Hotel has 91 rooms
Best Western Plus Santee Inn in Santee
+1-888-305-3366
I 95 Exit 98, Santee, SC 29142
  • Mid-scale hotel
  • Free complimentary breakfast
Econo Lodge in Santee
+1-800-881-1523
9112 Old Number 6 Highway, Santee, SC 29142
  • Cheap Highway hotel
  • Check in time: 11:00
  • Broken toilet paper
  • Generally quite dirty
Rodeway Inn
+1-888-283-3404
9117 Old Number 6 Highway, Santee, SC 29142
  • Low priced Highway property
  • Check in time: 11:00
Super 8 by Wyndham Santee
+1-866-221-8581
9125 Old Highway 6, Santee, SC 29142
  • Cheap Highway property
  • 41 sleeping rooms in hotel
Days Inn Summerton : 400 Buff Blvd.
+1-866-429-5787
400 Buff Blvd., Summerton, SC 29148 ~10.34 miles northeast of Santee
  • Cheap hotel
Americas Best Value Inn
+1-888-690-5281
401 Buff Blvd., Columbia, SC 29148 ~11.09 miles northeast of Santee
  • Two-star hotel
  • Check-in time: 15:00
Days Inn Orangeburg South : 3402 Five Chop Rd.
+1-888-690-5247
3402 Five Chop Rd., Orangeburg, SC 29115 ~14.02 miles west of Santee
  • Low-priced Highway hotel
  • Check-in: 2pm
From$60
Average 3.0 /5Reviews CallBookMore Details
Peachtree Inn
+1-888-305-3366
111 Conners Dr., Saint George, SC 29477 ~15.51 miles south of Santee
  • 3-star Highway hotel
  • Hotel has 39 rooms
From$49
Very Good 4.0 /5Reviews CallBookMore Details
Knights Inn Manning Sc : 6137 Alex Harvin Highway
+1-800-881-1523
6137 Alex Harvin Highway, Manning, SC 29102 ~16.15 miles northeast of Santee
  • 2 star property
  • 58 sleeping rooms in hotel
Sunset Inn Manning
+1-888-283-3404
5932 Alex Highway, Manning, SC 29102 ~16.27 miles northeast of Santee
  • Low priced property
From$50
Not Good 1.5 /5Reviews CallBookMore Details
Hampton Inn
+1-866-221-8581
2822 Paxville Highway, Manning, SC 29102 ~19.30 miles northeast of Santee
  • Mid-scale Highway property
  • 3 floors in hotel
Quality Inn
+1-866-429-5787
3031 Paxville Highway, Manning, SC 29102 ~19.32 miles northeast of Santee
  • Low-priced Golf Course property
  • 2 floors in property
  • Almost all guests complained about the bathroom
  • Bathroom could be optimized
Fairfield Inn Orangeburg
+1-888-690-5281
663 Citadel Rd., Orangeburg, SC 29118 Website ~20.26 miles west of Santee
  • Three Star Highway property
  • Gym is available on property
  • Good accessibility by car
  • Older building
Country Inns & Suites Orangeburg
+1-888-690-5247
731 Citadel Rd., Orangeburg, SC 29118 ~20.37 miles west of Santee
  • 3-star Highway hotel
  • 28 suites in property
From$103
Very Good 4.0 /5Hotel Reviews CallBookMore Details
Baymont by Wyndham Manning
+1-888-305-3366
2284 Raccoon Rd., Manning, SC 29102 ~20.37 miles northeast of Santee
  • Inexpensive Rural property
  • Check-in time: 2:00 pm
From$60
Very Good 4.0 /5Reviews CallBookMore Details
Comfort Inn & Suites - Orangeburg
+1-800-881-1523
746 Citadel Rd., Orangeburg, SC 29118 ~20.37 miles west of Santee
  • 2-star Rural hotel
  • Complimentary breakfast is offered
  • Decent breakfast
  • Clean hotel
TRU by Hilton Orangeburg Sc
+1-888-283-3404
739 Citadel Rd., Orangeburg, SC 29118 ~20.40 miles west of Santee
  • Three Star property
  • Access to gym on-site
From$90
Very Good 4.5 /5Review Score CallBookMore Details
Next 25 Santee Hotels >  [1 - 25 of 50]    
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Bar Chart: Upcoming 20 Days of Santee Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Santee, SC discounts available. The chart reflects the cheapest Santee hotel for each day and each star rating category.

Santee is in Orangeburg County, on the southern shore of South Carolina's largest freshwater lake, Lake Marion. When driving south on Interstate 95, visitors must cross a modern bridge over the lake to enter Santee. The historic bridge that runs alongside the new bridge is used as a fishing pier today. Covering more than 110,000 acres, Lake Marion is often referred to as South Carolina's inland sea. Known for trophy-quality game fish and beautiful scenery, the lake and neighboring Santee State Park offer boating, hiking, camping, birding, and biking.

You'll find a glorious trifecta of golf minutes from Santee's town center: Lake Marion Golf Course, Santee National Golf Club, and Santee Cooper Country Club courses. You'll discover four more courses within 20 minutes and about another 10 greens within a 45-minute drive. Dozens of affordable hotels exist in Santee, which make this small town South Carolina's value golf destination.

When should you visit Santee, SC?

The weather in Santee is humid most of the year. Some months are more pleasant than others. For the hottest weather, visit during July and August, when most days are in the high 80s and low 90s Fahrenheit. Since wind may affect your golf game, it's good to know that the wind in Santee is generally calm. The area experiences light breezes in April, plus moderate breezes in February and early March.

As for precipitation, the rainiest month is July, and the driest months are May, October, and November. The best time to visit for the least wind, rain, and humidity is usually late March through mid-May and October through November. During these months, the weather is moderate, with daily highs between 60 and 80 degrees.

Despite being the hottest and rainiest time of year, July is the busiest month for tourism in Santee, followed by March and June. Hotel prices are more expensive during these times of high demand. Try to book around these months to achieve the best hotel rates for your stay.

Below is a chart of the current pricing seasonality of hotels and motels in Santee, SC:

seasonality of hotel rates in Santee

Averate Rates by Star Rating

Below are 3 charts displaying average nightly cost trends by star rating class in Santee, SC. Analyze these charts to calculate the cheapest seasons to stay in Santee for your upcoming travels.

What are the luxury hotels in Santee, SC?

If you want to know about luxury hotels in Santee, South Carolina, then consider staying a few nights in downtown Charleston. Ranked the No. 1 hotel in Charleston and the No. 2 hotel in the United States, The Spectator Hotel exudes refinement and five-star luxury. The ambiance is a mix of Old Southern glamour and Jazz Age charisma.

All-inclusive amenities include 24-hour valet parking and concierge service, a hotel cocktail bar, in-room gourmet continental breakfast, pristine spa-like bathrooms, and Wi-Fi. Personable butlers are the charming face of the hotel and provide luxuries such as complimentary packing and unpacking, pressing services, coffee service, and more. Discounts for older adults are available.

What are the budget-friendly hotels in Santee, SC?

3 Star Average Prices: $119.73

The newly renovated Comfort Inn & Suites is one of the most budget-friendly hotels in Santee, South Carolina, that has special AAA member rates and rates for older adult travelers. With easy access to attractions and town amenities, Comfort Inn offers an excellent home base for your stay. Rooms feature premium bedding, flat-screen TVs, free Wi-Fi, microwaves, and refrigerators. Start the morning with a free hot breakfast or a workout in the fitness center. The average group discount at Comfort Inn reflects a certain percentage off the open booking rate, with the lowest rates offered during August and November.

Guests on a budget often stay at the Days Inn by Wyndham Orangeburg South, about 15 miles west of Santee. By staying outside the town, you'll find hotel rates become more affordable, and you're still within easy driving distance to all the area has to offer. The Days Inn offers a free breakfast with healthy options, in-room coffee and tea, and Wi-Fi. Government and military discounts are also offered to guests who qualify for them.

3 Star Hotel Prices in Santee

2 Star Average Prices: $73.50

2 Star Hotel Prices in Santee

What are the best hotels with discounts in Santee, SC?

The Holiday Inn is one of the best hotels with discounts in Santee, South Carolina. Discounts for members of the military, government, and older adults are all available at this hotel known for being clean and friendly. Group discounts are offered as well, although you'll want to book outside of June and September for deeper discounts. Receive further discounts at Holiday Inn if you're traveling with young ones. Kids ages 18 and younger stay for free, and up to four kids ages 11 and younger eat for free at the hotel restaurant.

Kem's Cafe is the on-site eatery at the Holiday Inn and serves breakfast and dinner daily. As for other amenities, you'll find a heated indoor pool, 24-hour business center, cocktail lounge, fitness center, free Wi-Fi, and guest laundry facilities. Free coffee is always served hot and fresh in the lobby. Rooms are equipped with mini-refrigerators, microwaves, coffee makers, hair dryers, and irons. Relax in a comfortable double, queen, or king bed while watching a flat-screen TV with free cable programming.

The Quality Inn & Suites is another great choice for the best hotel with discounts in Santee, South Carolina. Located in the same area of town, this hotel is also near shops, restaurants, and Interstate 95. The discounts available at Quality Inn & Suites are for members of AAA, members of the military or government, and older adults. A free hot and fresh breakfast is served every morning. In the evening, you can enjoy a drink or a delicious meal at the on-site restaurant, Ziggy's Bar and Grill. An outdoor pool is open during the warmer months.

The Quality Inn & Suites is friendly to business travelers and offers amenities such as free Wi-Fi, weekday newspapers, and meeting rooms. A coffee shop for grab-and-go items is in the lobby, and for unwinding after work, you'll find a putting green outside. Guest rooms feature comfortable, premium mattresses and linens, plus a generous helping of fluffy pillows and soft, plush blankets. The usual in-room amenities such as a microwave and refrigerator are available at this hotel.

What are the best hotel value options in Santee, SC?

Discover one of the best value options you'll find in Santee, South Carolina, situated outside of the Lake Marion Golf Course. The Best Western Plus Santee Inn offers cozy, ground-level rooms with free parking. You'll find upgraded bath amenities, an in-room mini-fridge, and a spacious work desk in your room at this comfortable and well-appointed inn. A deluxe continental breakfast is served for free each morning, with other sit-down meals available at the on-site restaurant throughout the day.

At the Best Western Plus Santee Inn, you'll also be able to relax outdoors by the well-kept heated pool or on the patio decorated with flowers and greenery. A fitness room, laundry room, and business center are all here for guest convenience. Discounts are available at this location if you are a member of AAA, the military, or the government. Older adult travelers can request a special rate, too. You'll appreciate that this hotel offers mobility features such as accessible doors, doorways, a bathroom, room controls, and clear floor space.

The Hampton Inn is another hotel that offers the most features at the best price. Friendly staff, clean rooms, and comfortable beds await guests. A free hot breakfast, daily newspapers, and Wi-Fi are only the start to the amenities offered. Are you in a hurry in the morning? Ask for an "On the Run" breakfast bag during the week. Groups can receive a discount when booking their accommodations at the Hampton Inn. If traveling together in the spring, group rates are highest in April. Book during the months of March or May for the best value.

Are there any good local eats in Santee, SC?

Explore some tasty dining options in Santee, South Carolina, with restaurants close to many hotels and attractions. A local favorite, Captain's Quarters is the place to go for some of the area's best steak and seafood. Another local gem is Clark's Inn & Restaurant. A gathering place for almost 75 years, Clark's serves Southern cuisine and spirits in a pub-like atmosphere with fireside dining.

Of course, a visit to the South wouldn't be complete without eating some great barbecue. The Lone Star Barbecue & Mercantile is a family-owned barbecue buffet featuring a special meal each night. Maurice's Gourmet BBQ serves up good Southern barbecue with traditional yellow sauce. Last, but not least, is Sweatman's BBQ, a charming old farmhouse that's home to a family-owned restaurant serving all-you-can-eat barbecue.

With many budget-friendly hotels in Santee, South Carolina, you'll be sure to find a hotel that best fits your needs. Many accommodations are located in town and close to all the amenities you need. You can't go wrong with any of the top places that have been highlighted above. Be sure to check out some of Santee's local eateries to experience the flavor of this small town with big charm.

FAQs about hotels in Santee

What are the most favored hotels in Santee?

Fairfield Inn & Suites by Marriott, Hampton Inn Santee I 95 and Best Western Plus Santee Inn are the best rated hotels based on customer reviews in the last 365 days.

What are the 4-5 star hotels in Santee?

Holiday Inn Santee, Hampton Inn Santee I 95 and Fairfield Inn & Suites by Marriott are the top 3 luxury hotels near Santee city center.

What hotels are closest to the city center of Santee?

Holiday Inn Santee, Comfort Inn & Suites, and Red Roof Inn are the properties closest to Santee city center.

How much does a cheap hotel in Santee cost per night?

In the last year, a 2 star hotel in Santee can be as cheap as $73.50 per night. (based on HotelPlanner prices)

How much does a 3 star hotel in Santee cost per night?

In the last year, the average 3 star hotel in Santee has been $119.73 per night. (based on HotelPlanner prices)

What are the best independent hotels in Santee?

Peachtree Inn, Country Inns & Suites Orangeburg and Southern Lodge are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels in Santee?

Fairfield Inn & Suites by Marriott and Fairfield Inn Orangeburg are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Santee?

Comfort Inn & Suites, Quality Inn and Comfort Inn & Suites are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best Best Western hotels in Santee?

Best Western Plus Santee Inn and SureStay Hotel by Best Western Manning are the best rated Best Western branded hotels (based on user reviews score).

What are the best IHG hotels in Santee?

Holiday Inn Santee and Holiday Inn Express & Suites of Orangeburg are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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