Star Rating
Hotel Name
Price Range (USD)to
Amenities

Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles west of Lake Marion Resort and Marina and 18 miles east of Edisto Memorial Gardens.

Santee Hotels, Motels & Accommodations

Days Inn 9074 Old Highway Six, Santee, SC 29142
  • Economy hotel
Holiday Inn Santee 139 Bradford Blvd., Santee, SC 29142
  • Three Star Highway hotel
  • Gym / Fitness Center Available
Comfort Inn & Suites : 221 Britain St. 221 Britain St., Santee, SC 29142
  • 2 star Lake hotel
  • 61 rooms in hotel
  • Copious breakfast
  • Clean room
Quality Inn & Suites
+1-888-690-5247
8929 Old Number Six Highway, Santee, SC 29142
  • Low Cost Highway property
  • Check in: 3:00PM
Howard Johnson - Santee 249 Britain St., Santee, SC 29142
  • Cheap Golf Course property
  • Check in: 03:00pm
Red Roof Inn 9091 Old No 6 Highway, Santee, SC 29142
  • Economical Golf Course property
  • Complimentary breakfast is offered
Whitten Inn
+1-888-283-3404
123 Mall St., Santee, SC 29142
  • Cheap Highway hotel
  • Free comp. breakfast
Hampton Inn Santee I 95 - Santee
+1-800-997-5149
9060 Old #6 Highway, Santee, SC 29142
  • 3 star Highway property
  • Free complimentary breakfast
  • Nice building
  • Tasty breakfast
From$89
Very Good 4.5 /5Review Score Call
Best Western Plus Santee Inn : 9059 Old Number Six Highway 9059 Old Number Six Highway, Santee, SC 29142
  • 3 star hotel
  • Check in: 01:00
Econo Lodge 9112 Old Number 6 Highway, Santee, SC 29142
  • Inexpensive Highway hotel
  • 37 rooms in hotel
Rodeway Inn 9117 Old Number 6 Highway, Santee, SC 29142
  • Low Cost Highway hotel
  • Free breakfast
Days Inn Summerton 400 Buff Blvd., Summerton, SC 29148 ~10.34 miles northeast of Santee
  • Two star property
  • Check-in time: 11:00 AM
Days Inn Orangeburg South : 3402 Five Chop Rd. 3402 Five Chop Rd., Orangeburg, SC 29115 ~14.02 miles west of Santee
  • Low Cost Highway property
  • Check in time: 2pm
Peachtree Inn 111 Conners Dr., Saint George, SC 29477 ~15.51 miles south of Santee
  • Affordable Highway property
  • 39 rooms in property
Sunset Inn Manning
+1-888-283-3404
5932 Alex Highway, Manning, SC 29102 ~16.27 miles northeast of Santee
  • 2-star hotel
Hampton Inn : 2822 Paxville Highway 2822 Paxville Highway, Manning, SC 29102 ~19.30 miles northeast of Santee
  • Affordable Highway hotel
  • 3 floors in hotel
Quality Inn : 3031 Paxville Highway 3031 Paxville Highway, Manning, SC 29102 ~19.32 miles northeast of Santee
  • Economy Golf Course hotel
  • Check in time: 2:00 pm
  • Room cleanliness is acceptable
  • Nearby town
Fairfield Inn Orangeburg 663 Citadel Rd., Orangeburg, SC 29118 ~20.26 miles west of Santee
  • Mid-scale Highway property
  • Comp. Breakfast
  • Friendly staff
  • Hotel staff was amazing
From$109
Very Good 4.0 /5Review Score Call
Country Inn & Suites Orangeburg 731 Citadel Rd., Orangeburg, SC 29118 ~20.37 miles west of Santee
  • 2-star hotel
  • Hotel has 28 suites
From$79
Average 3.5 /5Reviews Call
Comfort Inn & Suites in Orangeburg 746 Citadel Rd., Orangeburg, SC 29118 ~20.37 miles west of Santee
  • 2 star Rural property
  • 14 suites in property
  • Bathroom is ok
  • Excellent rooms with wonderful beds
Hampton Inn & Suites Orangeburg - Orangeburg 749 Citadel Rd., Orangeburg, SC 29118 ~20.42 miles west of Santee
  • Affordable Highway property
  • 32 suites in hotel
From$119
Excellent 5.0 /5Latest Reviews Call
Days Inn in Manning
+1-800-881-1523
2825 Paxville Highway, Manning, SC 29102 ~20.47 miles northeast of Santee
  • Two-star property
Southern Lodge 3616 St. Matthews Rd., Orangeburg, SC 29118 ~20.48 miles west of Santee
  • Economy Highway hotel
  • Check-in time: 2.00pm
  • Fair Hotel
  • Welcome with a smile
Days Inn Orangeburg - Orangeburg
+1-800-997-5149
3691 St. Matthews Rd., Orangeburg, SC 29118 ~20.50 miles west of Santee
  • Low Cost Highway property
Quality Inn & Suites 3671 St. Matthews, Orangeburg, SC 29118 ~20.51 miles west of Santee
  • 2-star Rural hotel
  • Free complimentary breakfast
Next 25 Santee Hotels >  [1 - 25 of 50]    
Next: See My Santee Hotels with Pricing
Back to Top