Star Rating
Hotel Name
Price Range (USD)to
Amenities

Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles west of Lake Marion Resort and Marina and 18 miles east of Edisto Memorial Gardens.

Santee Hotels, Motels & Accommodations

Days Inn 9074 Old Highway Six, Santee, SC 29142
  • Cheap property
Holiday Inn Santee in Santee 139 Bradford Blvd., Santee, SC 29142
  • Midscale Highway property
  • 4 floors in hotel
Comfort Inn & Suites 221 Britain St., Santee, SC 29142
  • Economy Lake hotel
  • 20 suites in property
  • Average cleanliness
  • Popular among couples
Quality Inn & Suites in Santee
+1-888-283-3404
8929 Old Number Six Highway, Santee, SC 29142
  • Low priced Highway hotel
  • Free breakfast
Red Roof Inn - Santee 9091 Old No 6 Highway, Santee, SC 29142
  • Two-star Golf Course property
  • Check-in time: 1.00
Howard Johnson - Santee 249 Britain St., Santee, SC 29142
  • Cheap Golf Course hotel
  • Free comp. breakfast
Whitten Inn : 123 Mall St.
+1-888-690-5281
123 Mall St., Santee, SC 29142
  • Economy Highway property
  • 117 sleeping rooms in hotel
Hampton Inn Santee I 95
+1-888-690-5247
9060 Old #6 Highway, Santee, SC 29142
  • Mid-scale Highway property
  • Check-in: 3:00 pm
  • Most guests thought rooms were spacious
  • Caring and attentive staff
Best Western Plus Santee Inn : I 95 Exit 98 I 95 Exit 98, Santee, SC 29142
  • Three Star property
  • Free breakfast available
Econo Lodge : 9112 Old Number 6 Highway 9112 Old Number 6 Highway, Santee, SC 29142
  • 2 star Highway hotel
  • Hotel has 37 rooms
Rodeway Inn : 9117 Old Number 6 Highway 9117 Old Number 6 Highway, Santee, SC 29142
  • Low priced Highway property
  • Free comp. breakfast
Days Inn Summerton 400 Buff Blvd., Summerton, SC 29148 ~10.34 miles northeast of Santee
  • Low priced hotel
Days Inn Orangeburg South in Orangeburg 3402 Five Chop Rd., Orangeburg, SC 29115 ~14.02 miles west of Santee
  • Economy Highway hotel
  • Check-in time: 2pm
Peachtree Inn 111 Conners Dr., Saint George, SC 29477 ~15.51 miles south of Santee
  • Three Star Highway hotel
  • 39 rooms in hotel
From$49
Very Good 4.0 /5Read Reviews CallBookMore Details
Sunset Inn Manning
+1-888-690-5247
5932 Alex Highway, Manning, SC 29102 ~16.27 miles northeast of Santee
  • Low-priced hotel
Hampton Inn : 2822 Paxville Highway 2822 Paxville Highway, Manning, SC 29102 ~19.30 miles northeast of Santee
  • Mid-scale Highway property
  • Free comp. breakfast
Quality Inn - Manning 3031 Paxville Highway, Manning, SC 29102 ~19.32 miles northeast of Santee
  • Inexpensive Golf Course property
  • 2 floors in hotel
  • Room cleanliness is acceptable
  • Almost all guests complained about the bathroom
Fairfield Inn Orangeburg : 663 Citadel Rd. 663 Citadel Rd., Orangeburg, SC 29118 ~20.26 miles west of Santee
  • Mid-scale Highway property
  • Fitness + Health Center
  • AC was not working
  • No hot water
From$94
Very Good 4.0 /5Read Reviews CallBookMore Details
Country Inn & Suites Orangeburg 731 Citadel Rd., Orangeburg, SC 29118 ~20.37 miles west of Santee
  • Cheap property
  • Comp. Breakfast
Comfort Inn & Suites - Orangeburg 746 Citadel Rd., Orangeburg, SC 29118 ~20.37 miles west of Santee
  • Low-priced Rural hotel
  • 69 sleeping rooms in hotel
  • Most guests said rooms were clean
  • Great rate
From$90
Very Good 4.0 /5Review Score CallBookMore Details
Hampton Inn & Suites Orangeburg 749 Citadel Rd., Orangeburg, SC 29118 ~20.42 miles west of Santee
  • 3 star Highway property
  • 32 suites in hotel
From$124
Very Good 4.5 /5Read Reviews CallBookMore Details
Days Inn - Manning
+1-888-690-5247
2825 Paxville Highway, Manning, SC 29102 ~20.47 miles northeast of Santee
  • Cheap property
Southern Lodge 3616 St. Matthews Rd., Orangeburg, SC 29118 ~20.48 miles west of Santee
  • Cheap Highway hotel
  • 43 sleeping rooms in hotel
  • Did not provide shampoo
  • World class service
Travelodge Orangeburg : 3620 St. Matthews Rd. 3620 St. Matthews Rd., Orangeburg, SC 29118 ~20.48 miles west of Santee
  • 2-star Highway hotel
Sleep Inn Orangeburg 3689 Saint Matthews Rd., Orangeburg, SC 29118 ~20.49 miles west of Santee
  • Two star Suburban hotel
  • Complimentary breakfast is offered
Next 25 Santee Hotels >  [1 - 25 of 50]    
Next: See My Santee Hotels with Pricing
Back to Top