Santee South Carolina Accommodations

Find the perfect hotel in Santee using our hotel guide provided below. Search for the cheapest discounted hotel and motel rates in or near Santee, SC for your upcoming personal or group trip. Discover the most favored Santee South Carolina hotel/motel rooms. Review the Santee hotel list below to find the perfect lodging. We also have a map of the Santee hotels. Coordinating a group? Get Santee Group Hotel Discounts

The Santee center point is around 2 miles from Lake Marion Resort and Marina and 18 miles from Edisto Memorial Gardens.

Find my perfect hotel Rooms Check-In Check-Out  
Show Calendar Show Calendar Start My Search >
(select the discounts you qualify for)
Star Rating




Hotel Name

Price Range (USD)
to
Amenities







Set My Filter

Santee Hotels, Motels & Accommodations

Days Inn - Santee
+1-800-230-4134Check Rates
9074 Old Highway Six, Santee, SC 29142
  • Cheap hotel
Exterior of Holiday Inn SanteeHoliday Inn Santee : 139 Bradford Blvd.
+1-800-997-5148Check Rates
139 Bradford Blvd., Santee, SC 29142
  • 3.0/5, Average Read Reviews
  • Affordable Highway hotel
  • 84 sleeping rooms in hotel
Image of Comfort Inn & SuitesComfort Inn & Suites : 221 Britain St.
+1-800-997-5149Check Rates
221 Britain St., Santee, SC 29142
Image of Quality Inn & SuitesQuality Inn & Suites in Santee
+1-800-230-4134Check Rates
8929 Old Number Six Highway, Santee, SC 29142
  • 3.0/5, Average Recent Reviews
  • Low priced Highway property
  • 17 suites in hotel
Photo of Howard Johnson SanteeHoward Johnson Santee
+1-800-997-5148Check Rates
249 Britain St., Santee, SC 29142
  • 3.0/5, Average Latest Reviews
  • Low priced Golf Course property
  • 60 rooms in property
Photo of Whitten InnWhitten Inn
+1-800-997-5149Check Rates
123 Mall St., Santee, SC 29142
  • 2.5/5, Poor Read Reviews
  • 2-star Highway hotel
  • 2 floors in property
Hampton Inn Santee I 95 - Santee
+1-800-230-4134Check Rates
9060 Old #6 Highway, Santee, SC 29142
  • 4.5/5, Very Good Review Score
  • 3 star Highway hotel
  • 3 floors in property
Best Western Plus Santee Inn - Santee
+1-800-997-5148Check Rates
9059 Old Number Six Highway, Santee, SC 29142
  • Three Star property
Rodeway Inn Santee : 9117 Old Number 6 Highway
+1-800-997-5149Check Rates
9117 Old Number 6 Highway, Santee, SC 29142
  • 3.0/5, Average Reviews
  • 2 star Highway hotel
  • Free breakfast
Travelodge : 9091 Old Highway 6
+1-800-230-4134Check Rates
9091 Old Highway 6, Santee, SC 29142
  • 2.5/5, Poor Reviews
  • Two star Golf Course property
  • 40 sleeping rooms in hotel
Econo Lodge
+1-800-997-5148Check Rates
9112 Old Number 6 Hww., Santee, SC 29142
  • Economy Highway hotel
  • 37 rooms in hotel
Peachtree Inn : 111 Conners Dr.
+1-800-997-5149Check Rates
111 Conners Dr., Saint George, SC 29477
  • 4.5/5, Very Good Recent Reviews
  • Affordable Highway hotel
  • 39 rooms in property
~15.51 Miles from Santee
Sunset Inn Manning : 5932 Alex Highway
+1-800-230-4134Check Rates
5932 Alex Highway, Manning, SC 29102~16.27 Miles from Santee
Hampton Inn
+1-800-997-5148Check Rates
2822 Paxville Highway, Manning, SC 29102
  • 4.5/5, Very Good Recent Reviews
  • Three Star Highway hotel
  • 73 rooms in hotel
~19.30 Miles from Santee
Quality Inn in Manning
+1-800-997-5149Check Rates
3031 Paxville Highway, Manning, SC 29102~19.32 Miles from Santee
Country Inn & Suites
+1-800-230-4134Check Rates
731 Citadel Rd., Orangeburg, SC 29118~19.66 Miles from Santee
Fairfield Inn Orangeburg
+1-800-997-5148Check Rates
663 Citadel, Orangeburg, SC 29118
  • 3.5/5, Average Read Reviews
  • Mid-scale hotel
  • 60 sleeping rooms in hotel
~20.28 Miles from Santee
Comfort Inn & Suites
+1-800-997-5149Check Rates
746 Citadel Rd., Orangeburg, SC 29118
  • 4.0/5, Very Good Read Reviews
  • Low Cost Rural property
  • Hotel has 14 suites
~20.37 Miles from Santee
Days Inn in Manning
+1-800-230-4134Check Rates
2825 Paxville Highway, Manning, SC 29102~20.47 Miles from Santee
Exterior of Southern LodgeSouthern Lodge in Orangeburg
+1-800-997-5148Check Rates
3616 St. Matthews Rd., Orangeburg, SC 29118 Website
  • Economy Highway hotel
  • Check-in time: 2.00pm
~20.48 Miles from Santee

 [1 - 20 of 50]   


Next: See My Santee Hotels with Pricing >