Holiday Inn Express & Suites Buffalo Downtown Medical Center An I

601 Main St., Buffalo, NY 14203 United States (USA) near Exit 7 on I-190 (~0.8mi)
View Map Reservations: 1-800-219-2797
2.5 Star Property
42.890205-78.872650
+1-800-219-2797
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Very Good
4.0/5

Based on 672 guest reviews

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  • Free comp. breakfast
  • Access to gym on-site
  • 146 sleeping rooms in hotel
  • 7 floors in property
  • 146 suites in property
  • Check in: 3:00pm
  • Groups/Meetings rating of 10.0/10

Check Current Prices






Standard prices by room type for the next 60 days

Rates shown are nightly rates before taxes and do not necessarily reflect all discounts available. The chart provides the cheapest public rates available by room type.

Room Types

Check Rates1 Bedroom 1 King Bed Suite
Non-Smoking
Check Rates1 Bedroom 1 Queen Bed Accessible Bathtub
Non-Smoking
Check Rates1 Bedroom King Suite
Non-Smoking
Check Rates1 Bedroom Queen Bed Accessible
Non-Smoking
Check Rates1 Bedroom Queen Room with Mobility Accessible Tub
Non-Smoking
Check Rates1 Bedroom Queen Suite with Roll in Shower Mobility Accessible
Non-Smoking
Check Rates1 Bedroom Suite
Non-Smoking
Check Rates1 Bedroom Suite Accessible
Non-Smoking
Check Rates1 Bedroom Suite King Bed
Non-Smoking
Check Rates1 Bedroom Suite Queen Bed Accessible
Non-Smoking
Check Rates1 King Bed 1 Bedroom Suite - Free Breakfast
Non-Smoking
Check Rates1 King Bed Suite
Non-Smoking
Check Rates1 King Bed and 1 Double Sofa Bed
Non-Smoking
Check Rates1 Queen 1 Bedroom Suite Accessible Roll Shower Free Breakfast
Non-Smoking
Check Rates1 Queen Bed Suite Accessible Roll in Shower
Non-Smoking
Check Rates1queen 1 Bedroom Suite Accessible Tub - Free Breakfast
Non-Smoking
Check RatesFree Breakfast
Non-Smoking
Check RatesQueen Suite with Roll in Shower Disability Accessible
Non-Smoking
Check RatesStandard Room, King or Two Doubles
Non-Smoking
Check RatesSuite 1 Bedroom
Non-Smoking
Check RatesSuite 1 Bedroom 1 King Bed
Non-Smoking
Check RatesSuite 1 Bedroom Mobility Accessible Bathtub
Non-Smoking
Check RatesSuite 1 Bedroom Mobility Accessible Bathtub 1 Queen Bed
Non-Smoking
Check RatesSuite 1 Bedroom Mobility Accessible Roll in Shower
Non-Smoking
Check RatesSuite 1 Bedroom Mobility Accessible Roll in Shower 1 Queen Bed
Non-Smoking
Check RatesSuite Accessible
Non-Smoking
Check RatesSuite Mobility Accessible Roll Shower
Non-Smoking
Check RatesSuite Mobility Accessible Tub
Non-Smoking
Check RatesSuite Queen Bed Accessible
Non-Smoking

Local Attractions

Sheas Performing Arts Center, First Niagara Center, Coca Cola Park(Buffalo Bisons), Naval Park, Buffalo Bandits, Buffalo Sabres, Buffalo Convention Center, Buffalo Zoo, Science Museum, University of Buffalo, Buffalo State College, Albright-Knox Art Gallery, Galleria Mall, Buffalo Bills, Niagara Falls.

Verified Reviews of Holiday Inn Express & Suites Buffalo Downtown Medical Center by I

Below are the verified reviews from guests that we have booked recently:
"Will Definitely Stay Again!"
Overall Score5.0/ 5
Staff was so kind and helpful, will definitely stay there on return trips.
(Individual traveler, booked 1 room), from US flag
11-Jun-2025 Verified Review, stayed from Tue Jun 10 to Wed Jun 11 2025 at a $187.57 average nightly rate.
"Didn't go event got canceled I forgot to cancel hotel."
Overall Score4.0/ 5
Forgot to cancel my room. As our event got canceled my bad expensive thing to forget.
(Individual traveler, booked 1 room), from US flag
01-Mar-2025 Verified Review, stayed from Wed Feb 26 to Thu Feb 27 2025 at a $401.98 average nightly rate.
"Great location, good price, safe, nice suites."
Overall Score3.0/ 5
I love the set up of suite rooms. Great location. Good price. Safe.
(Individual traveler, booked 1 room), from US flag
29-Jun-2024 Verified Review, stayed from Wed Jun 26 to Thu Jun 27 2024 at a $175.29 average nightly rate.
"Front desk have never been ruder!"
Overall Score1.0/ 5
We have stayed here 20 times in the last few years and this time was worse than ever!
(Individual traveler, booked 1 room), from US flag
17-Jun-2024 Verified Review, stayed from Sun Jun 16 to Mon Jun 17 2024 at a $160.99 average nightly rate.
"The room was clean, comfortable. The staff was friendly. "
Overall Score5.0/ 5
The room was clean, comfortable. The staff was friendly. every staff member was so kind and helpful.
(Individual traveler, booked 1 room), from US flag
18-May-2024 Verified Review, stayed from Thu May 16 to Fri May 17 2024 at a $194.99 average nightly rate.
4.0 out of 5. Based on 672 guest reviews

Property Description

The Comfort Suites® Downtown is a 100% non smoking all suite hotel located in the heart of downtown Buffalo's business, theatre and entertainment districts. This hotel just completed a full renovation of entire property including guestrooms and public spaces.Within walking distance from the Buffalo Niagara Convention Center, Shea's Performing Arts Center, and the HSBC Arena, which hosts many concerts and sporting events and is home to the NHL's Buffalo Sabres. All 146 guestrooms are 2 room king suites with livingroom area and bedroom. Each and every room has a king bed, workdesk, pullout couch, two 37" HDTV's with DVD player, micro/refrig unit, coffee maker, hairdryer, iron & ironing board and complimentary wireless internet.Hotel amenities include TGI Friday's restauarant on site, a brand new state of the art fitness center with nautilus and cardio equipment, business center with 2 computers and breakfast room with complimentary hot deluke breakfast each morning. Breakfast items include juice, meat, eggs, yogurt, cereals, breads, fruit and waffle station.Hotel also offers free parking just 1 block away, complimentary shuttle service with notice, valet laundry service, free newspaper, and free wireless internet throughout hotel.

Details / Other Expenses

Check In: 3:00pm
Check Out: 11:00am
Year of Last Renovation: 2018
Floors: 7
Rooms: 146
Corridors: All Rooms Have Interior Hallways
Non Smoking Rooms: 0
Handicap Rooms:
Suites: 146
Room Windows: Windows Don't Open
Cleaning Frequency: Daily
Meeting Rooms: 0
Dist. to Food/Bars: On-site
Dist. to 24hr Restaurant: 0.5 Mi
Dist. to Nearest Gym: On-site
Lounge/Bar Hours: 11am-1am
Ownership: Deirdre Dieter
Policies / Expenses
Cancellation:
Individual cancel policy 24 hours in advanceGroup cancel policy 2 weeks
Nightly Parking: $10
Total Taxes: 13.75%
Total Misc Fees: $0.00 USD
(mandatory resort fees/taxes)
State Tax: 8.75%
Occupancy Tax: 5.00%
Porterage Fee: 4.00 Per Person

Amenities / Features


  • Air conditioning
  • Alarm clock
  • ATM
  • Baggage storage facilities
  • Car rental
  • Central location
  • Complimentary breakfast
  • Complimentary newspaper
  • Credit card accepted: Mastercard/Visa
  • Credit card accepted: American Express
  • Credit card accepted: Discover
  • Credit card accepted: Diners Club
  • Electronic key card
  • Elevator
  • Express Check-Out
  • Facilities for the disabled
  • Fax available
  • Fitness and health center
  • Free local calls
  • Golf course on hotel grounds
  • Grocery service
  • Hairdryer available
  • Handicap accessible
  • Central heating
  • Ice Maker
  • Internet - wireless
  • Free WiFi Internet
  • Laundry facilities
  • Laundry valet service
  • Microwave in room
  • Non-smoking rooms
  • 24 hours opened
  • Office or business center
  • Private bathroom in room
  • Radio in room
  • Refrigerator
  • Restaurant
  • Self controlled heating/cooling system
  • Shop
  • Shower
  • Tea and coffee making facilities
  • Telephone in all rooms
  • Telephone - Free local calls
  • Television
  • TV - Free Cable
  • Voicemail

Airport & Shuttle Information

Buffalo International Airport 9 miles away.

Local Shuttle Info: none

Breakfast Information

Complimentary EXPRESS START™ BREAKFAST®The real breakfast of champions? The kind that’s complimentary and waiting for you every morning. We’ve got a whole buffet full of offerings ready to help kick start your day.

Pet Friendly?

Service animals complying with ADA Title lll regulations are allowed.

Sorry, pets are not allowed.

Parking Info

Off Site parking $15 per day

Internet / WiFI

Complimentary WiFi

About Holiday Inn Express

  • Free Express Start Breakfast
  • Have their own 100% Arabica Smart Roast Coffee
  • Free high-speed internet service in every room
  • eHost Online Concierge Service where guests can learn about hotel amenities, major airlines nearby, up-to-date local weather and even car rental services
  • Perfect for the business traveler on the go, Holiday Inn Express offers 24/7 hours & photocopy services

The Holiday Inn Express highlights above are subject to change without notice.

Suggested AI Generated Itinerary

    Day 1

  • Breakfast: Lake Effect Diner - A retro-style diner known for its hearty breakfast options. Located 1.2 miles from the hotel.
  • Lunch: Ted's Hot Dogs - A Buffalo institution serving up delicious hot dogs and burgers. Located 2.3 miles from the hotel.
  • Dinner: Pearl Street Grill & Brewery - A popular local brewery and restaurant offering a variety of delicious dishes. Located 0.5 miles from the hotel.
  • Activity: Explore Buffalo City Hall - Take a guided tour of the stunning Art Deco-style City Hall building and enjoy panoramic views of the city from the observation deck. Located 0.3 miles from the hotel.

    • Day 2

  • Breakfast: Five Points Bakery - A cozy bakery known for its artisan bread and pastries. Located 2.5 miles from the hotel.
  • Lunch: Charlie the Butcher's Kitchen - Enjoy a classic Buffalo beef on weck sandwich at this local favorite. Located 3.7 miles from the hotel.
  • Dinner: Anchor Bar - The birthplace of Buffalo wings, this iconic restaurant offers a variety of wing flavors and other tasty dishes. Located 1.8 miles from the hotel.
  • Activity: Visit the Buffalo Zoo - Explore the diverse animal exhibits and learn about conservation efforts at this popular zoo. Located 4.2 miles from the hotel.

    • Day 3

  • Breakfast: Betty's - A charming brunch spot known for its creative menu and cozy atmosphere. Located 0.8 miles from the hotel.
  • Lunch: Duff's Famous Wings - Another legendary spot for Buffalo wings, known for their spicy and flavorful sauces. Located 5.6 miles from the hotel.
  • Dinner: Seabar - A trendy seafood restaurant offering a fusion of Asian and American flavors. Located 1.9 miles from the hotel.
  • Activity: Explore the Buffalo and Erie County Botanical Gardens - Wander through the beautiful gardens and greenhouses, showcasing a variety of plant species. Located 3.9 miles from the hotel.

Previously known as:
Comfort Suites Downtown, Holiday Inn Express & Suites Buffalo Downtown, Holiday Inn Express & Suites, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR, an I

Group vs. Individual Rates at Holiday Inn Express & Suites Buffalo Downtown Medical Center An I

Rate fluctuations of Holiday Inn Express & Suites Buffalo Downtown Medical Center An I

This chart illustrates trends of sleeping room prices for both group/meeting rates and the best online individual traveler prices our rate checker could find at the time the group/meeting offer was placed. The most competitive group/meeting rate displayed is 12.1% in the month of January 2023 and the highest average individual rate is $236 in the month of July 2023. This chart will show past seasonality and also project future months. If you are flexible with dates, you may want to consider staying at Holiday Inn Express & Suites Buffalo Downtown Medical Center An I in a month when rates are lower.

FAQs about Holiday Inn Express & Suites Buffalo Downtown Medical Center by I

What time is check in?

Check in time is 3:00pm based on the hotel's local time. Early check in may be available if requested at the front desk on the day of check-in.

What time is check out?

Check out time is 11:00am based on the hotel's local time. Late check out may be available if requested at the front desk during your stay.

How many rooms does Holiday Inn Express & Suites Buffalo Downtown Medical Center by I have?

There are 146 sleeping rooms in the hotel.

What kind of breakfast is at Holiday Inn Express & Suites Buffalo Downtown Medical Center by I?

Complimentary EXPRESS START™ BREAKFAST®The real breakfast of champions? The kind that’s complimentary and waiting for you every morning. We’ve got a whole buffet full of offerings ready to help kick start your day.

What parking is available at Holiday Inn Express & Suites Buffalo Downtown Medical Center by I?

Off Site parking $15 per day

How much does internet cost?

Complimentary WiFi

Can I get a AAA rate at Holiday Inn Express & Suites Buffalo Downtown Medical Center by I?

Sorry, this hotel does not offer AAA hotel discounts at this time.

Can I get a Senior or AARP rate at Holiday Inn Express & Suites Buffalo Downtown Medical Center by I?

Sorry, this hotel does not offer senior hotel discounts at this time.

Is there a gym at Holiday Inn Express & Suites Buffalo Downtown Medical Center by I?

Yes, there is a gym/fitness area available on-site at the property.

Testimonials:

Testimonials icon
"The quick return of bids was a plus. Allowing conference planners to contact the hotel directly is another plus. This website really is a great tool!" V.E. - Atlanta, GA

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