Residence Inn Jacksonville Mayo Clinic Area

4905 San Pablo Rd. South, Jacksonville, FL 32224 United States (USA)
View Map Reservations: 1-800-219-2797
3 Star Property
30.255069-81.4364632
+1-800-219-2797
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  • Groups & Meetings rating of 7.5/10

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Standard prices by room type for the next 60 days

Rates shown are nightly rates before taxes and do not necessarily reflect all discounts available. The chart provides the cheapest public rates available by room type.

Verified Reviews of Residence Inn Jacksonville Mayo Clinic Area

Below are the verified reviews from guests that we have booked recently:
"Beautiful and great location"
Overall Score5.0/ 5
The room was very nice and it was also clean. We were delighted with this Residence Inn. The location is also great and the grounds are beautiful.
(Individual traveler, booked 1 room), from US flag
15-Feb-2026 Verified Review, stayed from Thu Feb 12 to Fri Feb 13 2026 at a $222.99 average nightly rate.
"Clean great people convenient"
Overall Score5.0/ 5
We will be repeat customers.
(Individual traveler, booked 1 room), from US flag
12-Oct-2025 Verified Review, stayed from Sun Oct 12 to Mon Oct 13 2025 at a $229.99 average nightly rate.
"Perfect and beautiful."
Overall Score5.0/ 5
We had an excellent stay at this hotel while going to Mayo. They simply are the best. Everyone from the front desk personnel to the meal servers and the housekeepers were perfect and provided excellent quality services. We would go back to this facility in the future if needed.
(Individual traveler, booked 1 room), from US flag
01-Jul-2025 Verified Review, stayed from Sun Jun 29 to Tue Jul 01 2025 at a $190.50 average nightly rate.
"Our room was very clean."
Overall Score5.0/ 5
Our room was very clean and the staff and front desk was very accommodating and friendly….
(Individual traveler, booked 1 room), from US flag
17-Jun-2025 Verified Review, stayed from Tue Jun 17 to Wed Jun 18 2025 at a $216.99 average nightly rate.
"Comfortable Stay!"
Overall Score4.0/ 5
This was a nice place to stay, even with our dog. Everyone was very cordial.
(Individual traveler, booked 1 room), from US flag
17-May-2025 Verified Review, stayed from Wed May 14 to Fri May 16 2025 at a $234.99 average nightly rate.
"Superb!"
Overall Score5.0/ 5
Superb! The lady that checked me in was a star! Everything was excellent!
(Individual traveler, booked 1 room), from JM flag
02-Apr-2025 Verified Review, stayed from Mon Mar 31 to Thu Apr 03 2025 at a $270.99 average nightly rate.
"Very clean but over priced."
Overall Score4.0/ 5
The room was very clean and comfortable but not worth almost $300. Yes it is near Mayo Clinic so they “got you” there. They provide a shuttle to the hospital it not before 7 am. The highlight of the hotel is Mark in the bar/restaurant area. He is amazing.
(Individual traveler, booked 1 room), from US flag
04-Mar-2025 Verified Review, stayed from Mon Mar 03 to Tue Mar 04 2025 at a $237.99 average nightly rate.
4.0 out of 5. Based on 6 guest reviews

Details / Other Expenses

Ownership: San Pablo RI LLC
Policies / Expenses

Pet Friendly?

Service animals complying with ADA Title lll regulations are allowed.

Sorry, pets are not allowed.

About Residence Inn by Marriott

  • Extended stay hotel offering large 1- and 2- bedroom suites and studio suites
  • Full kitchens with refrigerators, microwaves, stoves, and coffee makers
  • Free hot breakfast and free Wi-Fi everywhere
  • Complimentary evening socials offering food and drinks for guests
  • Fitness center with modern equipment and TVs
  • Great outdoor space with barbeque and fire pits
  • Private meeting spaces perfect for events and family gatherings
  • Free grocery delivery service available
  • Dry cleaning and on-site laundry services
  • Pet friendly

The Residence Inn by Marriott highlights above are subject to change without notice.

FAQs about Residence Inn Jacksonville Mayo Clinic Area

What time is check out?

Check in time is 4 PM based on the hotel's local time. Early check in may be available if requested at the front desk on the day of check-in.

What time is check out?

Check in time is 12 noon based on the hotel's local time. Early check in may be available if requested at the front desk on the day of check-in.

Testimonials:

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"Great site and made planning feel a little more controllable since is it my first time looking into planning group retreats. Thanks for being there." M.W. - Tampa, FL

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