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Hotels Near Mayo Clinic Florida

Accommodations close to Mayo Clinic are shown in the list below sorted in the order of their distance (closest first). Browse our hotels to find accommodations near Mayo Clinic (Mayo Clinic) for your leisure or corporate trips. Mayo Clinic is located at 4500 San Pablo Rd S. We show the best lodging close to Mayo Clinic so you can review the available Mayo Clinic lodging below and securely book your ideal hotel.

Lodging & Accommodations close to Mayo Clinic

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches : 14390 Mayo Blvd. 14390 Mayo Blvd., Jacksonville, FL 32224
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~0.08 miles southwest of Mayo Clinic
~1 minute walk
  • 3 star Beach hotel
  • Fitness / Gym is on-site
More Photos Image of Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
From$50
Very good 4.0 /5 Latest Reviews Call BookMore Details
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The Inn at Mayo Clinic : 4420 Mary Brigh Dr. 4420 Mary Brigh Dr., Jacksonville, FL 32224
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~0.24 miles north of Mayo Clinic
~4 minute walk
  • 3-star Beach property
  • 78 suites in property
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From$99
Very good 4.0 /5 Reviews Call BookMore Details
Hilton Jacksonville at Mayo Clinic 4745 Transformation Wy, Jacksonville, FL 32224
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~0.45 miles southwest of Mayo Clinic
~8 minute walk
  • 4 star property
  • 21 suites in property
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From$169
Average 3.0 /5 Read Reviews Call BookMore Details
Residence Inn Jacksonville East : 4905 San Pablo Rd. South 4905 San Pablo Rd. South, Jacksonville, FL 32224
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~0.51 miles south of Mayo Clinic
~9 minute walk
  • 3-star property
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From$90
Excellent 5.0 /5 Review Score Call BookMore Details
Enso - Jacksonville 3650 Enso Wy, Jacksonville, FL 32224
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~1.24 miles north of Mayo Clinic
~22 minute walk
  • Luxurious Five Star Beach hotel
  • 4 floors in property
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From$225
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG 4791 Windsor Commons Court Jacksonville Fl 3222, Jacksonville, FL 32224
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~1.71 miles west of Mayo Clinic
  • 3-star Golf Course property
  • Check in time: 3:00 PM
More Photos Photo of Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
From$97
Very good 4.0 /5 Guest Reviews Call BookMore Details
Towneplace Suites & Hampton Inn Beach Blvd. Jacksonville 13741 Beach Blvd. Jacksonville Fl 32224, Jacksonville, FL 32224
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~2.13 miles northwest of Mayo Clinic
  • 3 star hotel
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic in Jacksonville 13733 Beach Blvd., Jacksonville, FL 32224
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~2.13 miles northwest of Mayo Clinic
  • 3 star Suburban hotel
  • Check-in time: 3:00 pm
More Photos Image of Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area 1220 Marsh Landing Pkwy., Jacksonville Beach, FL 32250
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~2.43 miles east of Mayo Clinic
  • 3-star Beach hotel
  • Free breakfast
More Photos Photo of Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
From$99
Very good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express Jacksonville Beach by IHG - Jacksonville Beach 1101 Beach Blvd., Jacksonville Beach, FL 32250
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~2.84 miles northeast of Mayo Clinic
  • Affordable Beach hotel
  • Check-in time: 3:00 pm
More Photos Exterior of Holiday Inn Express Jacksonville Beach by IHG
From$80
Very good 4.0 /5 Read Reviews Call BookMore Details
Four Points by Sheraton Jacksonville Beachfront : 11 1st St. North 11 1st St. North, Jacksonville Beach, FL 32250
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~3.40 miles northeast of Mayo Clinic
  • Mid-scale Beach property
  • 72 suites in hotel
More Photos Image of Four Points by Sheraton Jacksonville Beachfront
From$130
Very good 4.0 /5 Guest Reviews Call BookMore Details
Best Western Oceanfront in Jacksonville Beach 305 1st St. North, Jacksonville Beach, FL 32250
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~3.49 miles northeast of Mayo Clinic
  • 3-star Beach hotel
  • Comp. Breakfast
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From$80
Very good 4.0 /5 Reviews Call BookMore Details
Casa Marina Hotel 691 1st St. North, Jacksonville Beach, FL 32250
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~3.60 miles northeast of Mayo Clinic
  • Midscale Oceanfront property
  • 2 floors in property
More Photos Photo of Casa Marina Hotel
From$110
Average 3.5 /5 Guest Reviews Call BookMore Details
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Margaritaville Jacksonville 715 1st St. North, Jacksonville, FL 32250
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~3.63 miles northeast of Mayo Clinic
  • 4 star property
  • Check-in: 16:00
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From$200
Very good 4.0 /5 Review Score Call BookMore Details
Ponte Vedra Inn & Club 200 Ponte Vedra Blvd., Ponte Vedra Beach, FL 32082
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~3.78 miles east of Mayo Clinic
  • Luxurious 5-star Beach property
  • 315 sleeping rooms in hotel
More Photos Photo of Ponte Vedra Inn & Club
From$179
Very good 4.0 /5 Recent Reviews Call BookMore Details
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Hampton Inn Jacksonville Beach / Oceanfront 1515 1st St. North, Jacksonville Beach, FL 32250
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~3.91 miles northeast of Mayo Clinic
  • 3-star Beach property
  • Check in: 4:00 PM
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From$79
Very good 4.5 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Jacksonville Beach 1616 1st St. North, Jacksonville Beach, FL 32250
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~3.92 miles northeast of Mayo Clinic
  • 3-star Beach property
  • Hotel has 2 meeting rooms
More Photos Photo of Fairfield Inn & Suites by Marriott Jacksonville Beach
From$129
Very good 4.0 /5 Review Score Call BookMore Details
Courtyard by Marriott Jacksonville Beach Oceanfront in Jacksonville Beach 1617 1st St. North, Jacksonville Beach, FL 32250
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~3.93 miles northeast of Mayo Clinic
  • Midscale Beach property
  • 3 meeting rooms in property
More Photos Exterior of Courtyard by Marriott Jacksonville Beach Oceanfront
From$159
Very good 4.5 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Oceanfront Jacksonville Beach 1617 North 1st St., Jacksonville Beach, FL 32250
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~3.94 miles northeast of Mayo Clinic
  • Midscale Beach hotel
  • Fitness + Health Center
More Photos Exterior of Courtyard by Marriott Oceanfront Jacksonville Beach
From$199
Very good 4.5 /5 Guest Reviews Call BookMore Details
Red Roof Inn PLUS+ Neptune Beach - Jacksonville Beach : 1401 Atlantic Blvd. 1401 Atlantic Blvd., Neptune Beach, FL 32266
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~4.50 miles north of Mayo Clinic
  • 3-star Beach property
  • Check in: 03:00 PM
More Photos Exterior of Red Roof Inn PLUS+ Neptune Beach - Jacksonville Beach
From$53
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Jacksonville Town Center - Jacksonville 10573 Brightman Blvd., Jacksonville, FL 32246
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~4.96 miles west of Mayo Clinic
  • Affordable Downtown hotel
  • Hotel has 5 floors
More Photos Photo of Holiday Inn Express & Suites Jacksonville Town Center
From$89
Very good 4.0 /5 Latest Reviews Call BookMore Details
The Lodge and Club at Ponte Vedra Beach : 607 Ponte Vedra Blvd. 607 Ponte Vedra Blvd., Ponte Vedra Beach, FL 32082
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~4.96 miles southeast of Mayo Clinic
  • Luxury Five Star property
  • 66 sleeping rooms in hotel
More Photos Exterior of The Lodge and Club at Ponte Vedra Beach
From$250
Very good 4.0 /5 Review Score Call BookMore Details
One Ocean Resort and Spa 1 Ocean Blvd., Atlantic Beach, FL 32233
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~5.01 miles northeast of Mayo Clinic
  • Expensive Beach property
  • 193 rooms in property
More Photos Image of One Ocean Resort and Spa
From$131
Very good 4.0 /5 Reviews Call BookMore Details
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass - Ponte Vedra Beach 45 Tournament Players Club Blvd., Ponte Vedra Beach, FL 32082
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~5.10 miles southeast of Mayo Clinic
  • 3-star Resort hotel
  • Hotel has 127 rooms
More Photos Exterior of Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
From$129
Very good 4.5 /5 Read Reviews Call BookMore Details
Sawgrass Marriott Golf Resort & Spa - Ponte Vedra Beach 1000 Tournament Players Club Blvd., Ponte Vedra Beach, FL 32082
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~5.15 miles southeast of Mayo Clinic
  • High end Beach hotel
  • Check in time: 04:00 pm
More Photos Exterior of Sawgrass Marriott Golf Resort & Spa
From$129
Very good 4.0 /5 Guest Reviews Call BookMore Details

Next: Show All Available Mayo Clinic Hotels with Pricing

Bar Chart: Upcoming 20 Days of Mayo Clinic Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Pablo Keys, FL discounts available. The chart reflects the cheapest Pablo Keys hotel for each day and each star rating category.

What are the best hotels near Mayo Clinic?

HotelDescriptionLink
1. Courtyard by Marriott Jacksonville at Mayo Clinic Campus The Courtyard by Marriott Jacksonville at Mayo Clinic Campus is a popular 3-Star hotel located approx. 0.1 miles southwest of Mayo Clinic and roughly a 1 minute stroll by foot. Recent hotel guests gave this hotel a verified guest score of 4/5. Get the latest price
2. Inn at Mayo Clinic The Inn at Mayo Clinic is a favored 3-Star hotel located ~0.2 mi. north of Mayo Clinic and approx. a 3 minute walk by foot. With a verified guest score of 4/5, this makes it one of the most desirable hotels nearby Mayo Clinic. Get the latest price
3. Residence Inn Jacksonville East The Residence Inn Jacksonville East is an in demand 3-Star hotel located approx. 0.5 miles south of Mayo Clinic and roughly a 9 minute stroll by foot. With a average guest review rating of 5/5, this makes it one of the most desirable lodging options close to Mayo Clinic. Get the latest price
4. Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG The Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG is a popular 3 star hotel located approx. 1.7 miles west of Mayo Clinic and about a 3 min. drive. With a guest review score of 4 out of 5, this makes it one of the premium properties close to Mayo Clinic. Get the latest price
5. Hampton Inn Jacksonville The Hampton Inn Jacksonville is a popular 3 star hotel located approx. 2.4 miles east of Mayo Clinic and about a 4 min. drive. Recent guests gave this hotel an avg. guest review rating of 4 out of 5. Get the latest price

5 Best Hotels near Mayo Clinic

FAQs about hotels near Mayo Clinic

What are the most favored hotels near Mayo Clinic?

Residence Inn Jacksonville East, Hampton Inn Jacksonville Beach and Courtyard by Marriott Jacksonville Beach Oceanfront are the best rated hotels based on customer reviews in the last 365 days.

What are the most up-scale hotels near Mayo Clinic?

Enso, Ponte Vedra Inn & Club and The Lodge and Club at Ponte Vedra Beach are the top 3 luxury hotels near Mayo Clinic.

What hotels are closest to the area of Mayo Clinic?

Courtyard by Marriott Jacksonville at Mayo Clinic Campus, The Inn at Mayo Clinic, and Hilton Jacksonville at Mayo Clinic are the properties closest to Mayo Clinic.

What are the most popular independent hotels near Mayo Clinic?

The Inn at Mayo Clinic, Margaritaville Jacksonville and Ponte Vedra Inn & Club are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near Mayo Clinic?

Residence Inn Jacksonville East, Courtyard by Marriott Jacksonville Beach Oceanfront and Courtyard by Marriott Oceanfront Jacksonville Beach are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best IHG hotels near Mayo Clinic?

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG, Holiday Inn Express Jacksonville Beach by IHG and Holiday Inn Express & Suites Jacksonville Town Center are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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