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Hotels Near Mayo Clinic Florida

Accommodations close to Mayo Clinic are shown in the list below sorted in the order of their distance (closest first). Browse our hotels to find accommodations near Mayo Clinic (Mayo Clinic) for your leisure or corporate trips. Mayo Clinic is located at 4500 San Pablo Rd S. We show the best lodging close to Mayo Clinic so you can review the available Mayo Clinic lodging below and securely book your ideal hotel.

Lodging/Accommodations close by Mayo Clinic

Courtyard by Marriott Jacksonville at Mayo Clinic Campus / Beaches
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
14390 Mayo Boulevard, Jacksonville, FL 32224 ~0.19 miles southwest of Mayo Clinic
~3 minute walk
  • Midscale property
  • Hotel has 12 suites
More Photos Photo of Courtyard by Marriott Jacksonville at Mayo Clinic Campus / Beaches
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Very Good 8.4 /10 Review Score Call BookMore Details
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Landcom Hospitality Management
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
4314 Pablo Oaks Court Pablo Oaks Court, Jacksonville, Florida 32224 ~0.40 miles northwest of Mayo Clinic
~7 minute walk
  • Economy hotel
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Hilton Jacksonville at Mayo Clinic
+1-800-716-8490

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New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
4745 Transformation Way, Jacksonville, FL 32224 ~0.46 miles southwest of Mayo Clinic
~8 minute walk
  • property
  • 21 suites in hotel
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Excellent 9.2 /10 Recent Reviews Call BookMore Details
Residence Inn by Marriott Jacksonville - Mayo Clinic Area
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL 32224 ~0.51 miles south of Mayo Clinic
~9 minute walk
  • Three Star hotel
  • Check in: 4:00 PM - 6:00 AM
More Photos Photo of Residence Inn by Marriott Jacksonville - Mayo Clinic Area
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Excellent 9.4 /10 Guest Reviews Call BookMore Details
Home2 Suites by Hilton Jacksonville Mayo Clinic Area Beaches
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3609 San Pablo Parkway, Jacksonville, FL 32224 ~1.30 miles north of Mayo Clinic
~23 minute walk
  • Affordable property
  • 125 sleeping rooms in hotel
More Photos Photo of Home2 Suites by Hilton Jacksonville Mayo Clinic Area Beaches
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Holiday Inn Express & Suites Jacksonville SE- Med Center Area by IHG
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
4791 Windsor Commons Ct, Jacksonville, FL 32224 ~1.72 miles west of Mayo Clinic
  • Affordable hotel
  • Hotel has 5 floors
More Photos Image of Holiday Inn Express & Suites Jacksonville SE- Med Center Area by IHG
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Very Good 8.8 /10 Guest Reviews Call BookMore Details
Wingate by Wyndham Jacksonville
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
4791 WINDSOR COMMONS Court J.t. BULTER BLVD and HODGES, Jacksonville, FL 00 ~1.72 miles west of Mayo Clinic
  • Midscale property
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Relax Revive and Renew You
+1-888-311-4278

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New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
4460 Hodges Boulevard, Jacksonville, 32224 ~1.81 miles west of Mayo Clinic
  • Low-priced hotel
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Delightful Refurbished Apt! Everything you need!
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
4460 Hodges Blvd, Jacksonville, 322245201 ~1.81 miles west of Mayo Clinic
  • Cheap hotel
More Photos Exterior of Delightful Refurbished Apt! Everything you need!
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Relax Revive and Renew in a Great apt
+1-888-734-9421

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New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
4460 Hodges Boulevard, Jacksonville, 32224 ~1.81 miles west of Mayo Clinic
  • 3 star hotel
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Embassy Suites by Hilton Jacksonville at Glen Kernan Park
+1-888-841-5292

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New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
NWQ of J Turner Butler Boulevard, Jacksonville, FL 32224 ~1.96 miles west of Mayo Clinic
  • Expensive property
More Photos Image of Embassy Suites by Hilton Jacksonville at Glen Kernan Park
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TownePlace Suites by Marriott Jacksonville East
+1-888-455-5160

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New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
13741 BEACH BLVD, Jacksonville, FL 32224 ~2.10 miles northwest of Mayo Clinic
  • Three Star hotel
  • Hotel has 93 rooms
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Excellent 9.2 /10 Guest Reviews Call BookMore Details
Hampton Inn & Suites Jacksonville - Beach Blvd / Mayo Clinic
+1-888-965-8297

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New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
13733 Beach Blvd, Jacksonville, FL 32224 ~2.13 miles northwest of Mayo Clinic
  • 3-star property
  • 96 rooms in hotel
More Photos Photo of Hampton Inn & Suites Jacksonville - Beach Blvd / Mayo Clinic
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Excellent 9.0 /10 Review Score Call BookMore Details
More Homes & Apts at Booking.com

Book online or call +1-800-219-2797

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Hampton Inn Jacksonville / Ponte Vedra Beach-Mayo Clinic Area
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1220 Marsh Landing Pkwy, Jacksonville Beach, FL 32250 ~2.42 miles east of Mayo Clinic
  • Affordable hotel
  • Hotel has 5 floors
More Photos Exterior of Hampton Inn Jacksonville / Ponte Vedra Beach-Mayo Clinic Area
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Excellent 9.0 /10 Guest Reviews Call BookMore Details
Beach House With Private Heated Pool Close To Mayo
+1-888-749-6785

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New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
714 15th Ave. South, Jacksonville Beach, ~2.72 miles east of Mayo Clinic
  • Economical hotel
More Photos Exterior of Beach House With Private Heated Pool Close To Mayo
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Sunshine Hideaway - Large Studio - Pet Friendly
+1-888-878-9982

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New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
737 12Th Ave. South, Jacksonville Beach, FL 32250 ~2.74 miles east of Mayo Clinic
  • 3 star hotel
  • Check-in time: 16:00:00
More Photos Photo of Sunshine Hideaway - Large Studio - Pet Friendly
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Beach Getaway
+1-888-389-4485

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New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
630 11th Ave. S, Jacksonville Beach, FL 32250 ~2.82 miles east of Mayo Clinic
  • Luxurious 5 Star property
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Holiday Inn Express Jacksonville Beach by IHG
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1101 Beach Blvd, Jacksonville Beach, FL 32250 ~2.84 miles northeast of Mayo Clinic
  • Midscale hotel
  • Pets are Allowed
More Photos Image of Holiday Inn Express Jacksonville Beach by IHG
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Excellent 9.2 /10 Recent Reviews Call BookMore Details
Seventh Seas half mile to the beach pet friendly Near to the Mayo Clinic - UNF - TPC Sawgrass - Convention Center - Shopping Malls - Under 3 Hours from DISNEY
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
733 7th Ave. South, Jacksonville Beach, 32250 ~2.84 miles east of Mayo Clinic
  • 4 star hotel
  • Check in time: 16:00:00 - 00:00:00
More Photos Image of Seventh Seas half mile to the beach pet friendly Near to the Mayo Clinic - UNF - TPC Sawgrass - Convention Center - Shopping Malls - Under 3 Hours from DISNEY
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Not Good 1.0 /10 Guest Reviews Call BookMore Details
Beachykeen by Vtrips
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
2652 Almonaster St., Jacksonville, 32250 ~2.87 miles east of Mayo Clinic
  • Expensive property
More Photos Photo of Beachykeen by Vtrips
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Beachykeen - Four Bedroom Home
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
2652 Almonaster St., Jacksonville, 32250 ~2.89 miles east of Mayo Clinic
  • Three Star hotel
More Photos Image of Beachykeen - Four Bedroom Home
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Walk to Beach - Fully Renovated Modern Jax Beach Retreat
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
633 Gonzales Avenue, Jacksonville Beach, ~2.90 miles east of Mayo Clinic
  • 2 star hotel
More Photos Exterior of Walk to Beach - Fully Renovated Modern Jax Beach Retreat
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Modern Beach Gem close to Mayo and Beach
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1704 9th Ave. North, Jacksonville Beach, ~2.91 miles northeast of Mayo Clinic
  • Two-star hotel
More Photos Photo of Modern Beach Gem close to Mayo and Beach
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Sunny Day Getaway
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1139 5th Ave. N, Jacksonville, 32250 ~2.93 miles northeast of Mayo Clinic
  • Four star hotel
More Photos Photo of Sunny Day Getaway
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Gem 1
+1-888-311-4278

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New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
434 9th Ave. S, Jacksonville Beach, ~2.97 miles east of Mayo Clinic
  • 2-star property
More Photos Exterior of Gem 1
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Next: Show All Available Mayo Clinic Hotels with Pricing

What are the best hotels near Mayo Clinic?

HotelDescriptionLink
1. Courtyard by Marriott Jacksonville at Mayo Clinic Campus The Courtyard by Marriott Jacksonville at Mayo Clinic Campus is a leading 3 star hotel located approx. 0.2 miles southwest of Mayo Clinic and about a 3 min. stroll by foot. Recent guests gave this hotel a verified guest score of 8.4 out of 5. Get the latest price
2. Hilton Jacksonville at Mayo Clinic The Hilton Jacksonville at Mayo Clinic is a 4.5 star hotel located about 0.5 miles southwest of Mayo Clinic and approximately a 9 min. stroll. Recent travelers gave this hotel a guest review score of 9.2 out of 5. Get the latest price
3. Residence Inn by Marriott Jacksonville - Mayo Clinic Area The Residence Inn by Marriott Jacksonville - Mayo Clinic Area is a popular 3 star hotel located approx. 0.5 miles south of Mayo Clinic and about a 9 min. walk by foot. With a guest review score of 9.4 out of 5, this makes it one of the finest properties close to Mayo Clinic. Get the latest price
4. Holiday Inn Express & Suites Jacksonville SE- Med Center Area by IHG The Holiday Inn Express & Suites Jacksonville SE- Med Center Area by IHG is a favored 2.5-Star hotel located ~1.7 mi. west of Mayo Clinic and roughly a 3 minute drive or uber ride. With a average guest review rating of 8.8/5, this makes it one of the most outstanding hotel options nearby Mayo Clinic. Get the latest price

4 Best Hotels near Mayo Clinic

FAQs about hotels near Mayo Clinic

What are the most favored hotels near Mayo Clinic?

Residence Inn by Marriott Jacksonville - Mayo Clinic Area, Holiday Inn Express Jacksonville Beach by IHG and TownePlace Suites by Marriott Jacksonville East are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels near Mayo Clinic?

Beach Getaway, Hilton Jacksonville at Mayo Clinic and Embassy Suites by Hilton Jacksonville at Glen Kernan Park are the top 3 luxury hotels near Mayo Clinic.

What hotels are closest to the area of Mayo Clinic?

Courtyard by Marriott Jacksonville at Mayo Clinic Campus, Landcom Hospitality Management, and Hilton Jacksonville at Mayo Clinic are the properties closest to Mayo Clinic.

What are the best independent hotels near Mayo Clinic?

Rainey 5577, Spanish Trace 455 and Island South 35 are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near Mayo Clinic?

TownePlace Suites by Marriott Middleburg, Residence Inn by Marriott Jacksonville Downtown and TownePlace Suites Jacksonville Airport are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near Mayo Clinic?

Quality Inn & Suites Jacksonville-Baymeadows, WoodSpring Suites Jacksonville Beach Blvd and Comfort Suites St. Augustine Historic District Area are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best Best Western hotels near Mayo Clinic?

Best Western Historic Bayfront, Best Western Plus First Coast Inn & Suites and Best Western Oceanfront are the best rated Best Western branded hotels (based on user reviews score).

What are the best IHG hotels near Mayo Clinic?

Holiday Inn Express & Suites Kingsland I-95-Naval Base Area by IHG, Holiday Inn Express Jacksonville South Bartram Prk by IHG and Holiday Inn Express St. Augustine - Vilano Beach by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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