Accommodations close to Mayo Clinic are shown in the list below sorted in the order of their distance (closest first). Browse our hotels to find accommodations near Mayo Clinic (Mayo Clinic) for your leisure or corporate trips.
Mayo Clinic is located at 4500 San Pablo Rd S. We show the best lodging close to Mayo Clinic so you can review the available Mayo Clinic lodging below and securely book your ideal hotel.
How should we direct your call?
Book online or call +1-800-760-7718
Residence Inn Jacksonville East, Courtyard by Marriott Oceanfront Jacksonville Beac and Hilton Garden Inn Jacksonville are the best rated hotels based on customer reviews in the last 365 days.
Ponte Vedra Beach Resorts, The Lodge and Club at Ponte Vedra Beach and Margaritaville Jacksonville are the top 3 luxury hotels near Mayo Clinic.
Courtyard by Marriott Jacksonville at Mayo Clinic Campus, The Inn at Mayo Clinic, and Residence Inn Jacksonville East are the properties closest to Mayo Clinic.
The Inn at Mayo Clinic, Margaritaville Jacksonville and Ponte Vedra Beach Resorts are the best rated independent hotels (not part of a big brand).
Residence Inn Jacksonville East, Courtyard by Marriott Oceanfront Jacksonville Beac and Courtyard by Marriott Jacksonville at Mayo Clinic Campus are the best rated Marriott/Starwood branded hotels (based on customer reviews score).
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area, an IH, Holiday Inn Express Jacksonville Beach An Ihg Hotel and Holiday Inn Express & Suites Jacksonville Town Center are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).