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Hotels Near Mayo Clinic Florida

Accommodations close to Mayo Clinic are shown in the list below sorted in the order of their distance (closest first). Browse our hotels to find accommodations near Mayo Clinic (Mayo Clinic) for your leisure or corporate trips.Mayo Clinic is located at 4500 San Pablo Rd S. We show the best lodging close to Mayo Clinic so you can review the available Mayo Clinic lodging below and securely book your ideal hotel.

Lodging/Accommodations close by Mayo Clinic

Sonesta Select Jacksonville at Mayo Clinic Campus
+1-888-389-4121
14390 Mayo Blvd., Jacksonville, FL 32224 ~0.08 miles southwest of Mayo Clinic
~1 minute walk
  • Midscale Beach property
  • Gym is available on property
  • Terrific location
  • Paying for the higher room
The Inn at Mayo Clinic : 4420 Mary Brigh Dr.
+1-888-675-2083
4420 Mary Brigh Dr., Jacksonville, FL 32224 ~0.24 miles north of Mayo Clinic
~4 minute walk
  • Three Star Beach property
  • 78 suites in hotel
Residence Inn Jacksonville East
+1-800-716-8490
4905 San Pablo Rd. South, Jacksonville, FL 32224 ~0.51 miles south of Mayo Clinic
~9 minute walk
  • Three Star property
  • Check-in time: 15:00
Holiday Inn Express & Suites Jacksonville Se Med C
+1-800-805-5223
4791 Windsor Commons Court Jacksonville Fl 3222, Jacksonville, FL 32224 ~1.71 miles west of Mayo Clinic
  • 3 star Golf Course property
  • 5 floors in property
  • Reception is all right
  • Unit noisy
From$97
Very Good 4.0 /5Reviews CallBookMore Details
Towneplace Stes East Marriott - Jacksonville
+1-888-965-1860
13741 Beach Blvd., Jacksonville, FL 32224 ~2.09 miles northwest of Mayo Clinic
  • 3 star hotel
  • Gym / Fitness Center Available
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic : 13733 Beach Blvd.
+1-888-788-5576
13733 Beach Blvd., Jacksonville, FL 32224 ~2.13 miles northwest of Mayo Clinic
  • 3-star Suburban hotel
  • Comp. Breakfast
From$83
Very Good 4.5 /5Review Score CallBookMore Details
Hampton Inn Jacksonville Beach / Mayo Clinic East
+1-888-897-9207
1220 Marsh Landing Pkwy., Jacksonville Beach, FL 32250 ~2.43 miles east of Mayo Clinic
  • 3-star Beach hotel
  • Free breakfast available
Holiday Inn Express Jacksonville Beach : 1101 Beach Blvd.
+1-888-311-4278
1101 Beach Blvd., Jacksonville Beach, FL 32250 ~2.84 miles northeast of Mayo Clinic
  • Mid-scale Beach property
  • Check-in: 3:00 pm
From$80
Very Good 4.5 /5Reviews CallBookMore Details
Four Points by Sheraton Jacksonville Beachfront - Jacksonville Beach
+1-888-469-4795
11 1st St. North, Jacksonville Beach, FL 32250 ~3.40 miles northeast of Mayo Clinic
  • 3 star Beach property
  • Check-in time: 3:00 pm
  • Acceptable breakfast prices
  • No pool
From$130
Very Good 4.5 /5Reviews CallBookMore Details
Best Western Oceanfront in Jacksonville Beach
+1-888-734-9421
305 1st St. North, Jacksonville Beach, FL 32250 ~3.50 miles northeast of Mayo Clinic
  • Mid-scale Beach hotel
  • Free breakfast
Casa Marina Hotel & Restaurant - Jacksonville Beach
+1-888-841-5292
691 1st St. North, Jacksonville Beach, FL 32250 ~3.60 miles northeast of Mayo Clinic
  • Midscale Oceanfront hotel
  • 3 meeting rooms in hotel
  • Stylish Hotel
  • Classy place
Margaritaville Jacksonville
+1-888-455-5160
715 1st St. North, Jacksonville, FL 32250 ~3.63 miles northeast of Mayo Clinic
  • Midscale property
  • 172 sleeping rooms in hotel
Ponte Vedra Beach Resorts - Ponte Vedra Beach
+1-888-965-8297
200 Ponte Vedra Blvd., Ponte Vedra Beach, FL 32082 ~3.78 miles east of Mayo Clinic
  • Luxury Five Star Beach hotel
  • 315 rooms in hotel
  • Gym was great
  • Great view
From$179
Very Good 4.5 /5Reviews CallBookMore Details
Hampton Inn Oceanfront Jax Beach
+1-888-906-6358
1515 1st St. North, Jacksonville Beach, FL 32250 ~3.91 miles northeast of Mayo Clinic
  • Midscale Oceanfront property
  • Check in: 3:00 PM
  • Beach nearby
  • Most guests complained about the room service
From$119
Very Good 4.5 /5Reviews CallBookMore Details
Fairfield Inn & Suites by Marriott Jacksonville Be
+1-888-749-6785
1616 1st St. North, Jacksonville Beach, FL 32250 ~3.92 miles northeast of Mayo Clinic
  • Three Star Beach hotel
  • 3 floors in hotel
  • Popular among families
  • Beach nearby
From$129
Very Good 4.0 /5Reviews CallBookMore Details
Courtyard by Marriott Oceanfront Jacksonville Beac
+1-888-878-9982
1617 1st St. North, Jacksonville Beach, FL 32250 ~3.93 miles northeast of Mayo Clinic
  • Affordable Beach property
  • 3 meeting rooms in hotel
  • Average parking
  • Furniture needs more attention
From$159
Very Good 4.5 /5Reviews CallBookMore Details
Red Roof Inn PLUS+ Neptune Beach - Jacksonville Beach - Neptune Beach
+1-888-389-4485
1401 Atlantic Blvd., Neptune Beach, FL 32266 ~4.50 miles north of Mayo Clinic
  • 3 star Beach property
  • Comp. Breakfast
Holiday Inn Express & Suites Jacksonville Town Center - Jacksonville
+1-888-389-4121
10573 Brightman Blvd., Jacksonville, FL 32246 ~4.96 miles west of Mayo Clinic
  • Midscale Downtown hotel
  • Hotel has a green policy Read more
The Lodge and Club at Ponte Vedra Beach - Ponte Vedra Beach
+1-888-675-2083
607 Ponte Vedra Blvd., Ponte Vedra Beach, FL 32082 ~4.96 miles southeast of Mayo Clinic
  • Luxurious Five Star property
  • Fitness center on property
From$250
Very Good 4.5 /5Recent Reviews CallBookMore Details
One Ocean Resort & Spa in Atlantic Beach
+1-800-716-8490
1 Ocean Blvd., Atlantic Beach, FL 32233 ~5.01 miles northeast of Mayo Clinic
  • High-end Beach hotel
  • Fitness + Health Center
  • The majority of guests loved the menu selection
  • The majority of guests had problems with the shower
From$131
Very Good 4.5 /5Hotel Reviews CallBookMore Details
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Next: Show All Available Mayo Clinic Hotels with Pricing

Bar Chart: Upcoming 20 Days of Mayo Clinic Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Pablo Keys, FL discounts available. The chart reflects the cheapest Pablo Keys hotel for each day and each star rating category.

What are the best hotels near Mayo Clinic?

HotelDescriptionLink
1. Sonesta Select Jacksonville at Mayo Clinic CampusThe Sonesta Select Jacksonville at Mayo Clinic Campus is a popular 3-Star hotel located approx. 0.1 miles southwest of Mayo Clinic and roughly a 1 minute stroll by foot. Recent hotel guests gave this hotel a verified guest score of 4/5.Get the latest price
2. Inn at Mayo ClinicThe Inn at Mayo Clinic is a favored 3-Star hotel located ~0.2 mi. north of Mayo Clinic and approx. a 3 minute walk by foot. With a verified guest score of 4/5, this makes it one of the most desirable hotels nearby Mayo Clinic.Get the latest price
3. Holiday Inn Express & Suites Jacksonville Se Med CThe Holiday Inn Express & Suites Jacksonville Se Med C is a popular 3 star hotel located approx. 1.7 miles west of Mayo Clinic and about a 3 min. drive. With a guest review score of 4 out of 5, this makes it one of the finest hotels close to Mayo Clinic.Get the latest price
4. Hampton Inn & Suites Jacksonville - Beach BlvdThe Hampton Inn & Suites Jacksonville - Beach Blvd is an in demand 3 star hotel located approx. 2.1 miles northwest of Mayo Clinic and approximately a 4 min. car ride. With a aggregate guest review score of 4.5 out of 5, this makes it one of the terrific hotels close to Mayo Clinic.Get the latest price
5. Hampton Inn Jacksonville BeachThe Hampton Inn Jacksonville Beach is a popular 3 star hotel located approx. 2.4 miles east of Mayo Clinic and about a 4 min. drive. Recent guests gave this hotel an avg. guest review rating of 4.5 out of 5.Get the latest price

5 Best Hotels near Mayo Clinic

FAQs about hotels near Mayo Clinic

What are the top reviewed hotels near Mayo Clinic?

Hampton Inn & Suites Jacksonville - Beach Blvd, Hampton Inn Jacksonville Beach and Holiday Inn Express Jacksonville Beach are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near Mayo Clinic?

Ponte Vedra Beach Resorts, The Lodge and Club at Ponte Vedra Beach and One Ocean Resort & Spa are the top 3 luxury hotels near Mayo Clinic.

What hotels are closest to the area of Mayo Clinic?

Sonesta Select Jacksonville at Mayo Clinic Campus, The Inn at Mayo Clinic, and Residence Inn Jacksonville East are the properties closest to Mayo Clinic.

What are the most popular independent hotels near Mayo Clinic?

Ponte Vedra Beach Resorts, The Lodge and Club at Ponte Vedra Beach and One Ocean Resort & Spa are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near Mayo Clinic?

Courtyard by Marriott Oceanfront Jacksonville Beac, Fairfield Inn & Suites by Marriott Jacksonville Be and Sawgrass Marriott Golf Resort & Spa are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best IHG hotels near Mayo Clinic?

Holiday Inn Express Jacksonville Beach, Holiday Inn I 295 East Baymeadows and Holiday Inn Express & Suites Jacksonville Se Med C are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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