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Hotels Near Mayo Clinic Florida

Accommodations close to Mayo Clinic are shown in the list below sorted in the order of their distance (closest first). Browse our hotels to find accommodations near Mayo Clinic (Mayo Clinic) for your leisure or corporate trips. Mayo Clinic is located at 4500 San Pablo Rd S. We show the best lodging close to Mayo Clinic so you can review the available Mayo Clinic lodging below and securely book your ideal hotel.

Lodging & Accommodations close to Mayo Clinic

Courtyard by Marriott Jacksonville San Pablo in Jacksonville
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
14390 Mayo Blvd., Jacksonville, FL 32224 ~0.08 miles southwest of Mayo Clinic
~1 minute walk
  • Affordable Beach hotel
  • 3 floors in property
  • Most guests thought they were poorly maintained
  • Paying for the higher room
More Photos Photo of Courtyard by Marriott Jacksonville San Pablo
From$50
Very Good 4.0 /5 Guest Reviews Call BookMore Details
The Inn at Mayo Clinic : 4420 Mary Brigh Dr.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
4420 Mary Brigh Dr., Jacksonville, FL 32224 ~0.24 miles north of Mayo Clinic
~4 minute walk
  • Midscale Beach property
  • 3 floors in property
More Photos Photo of The Inn at Mayo Clinic
From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Jacksonville Se Med C
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
4791 Windsor Commons Court Jacksonville Fl 3222, Jacksonville, FL 32224 ~1.71 miles west of Mayo Clinic
  • Affordable Golf Course hotel
  • Hotel has 4 meeting rooms
  • The majority of guests found the staff to be very friendly
  • Almost all guests said the reception staff was ok
More Photos Exterior of Holiday Inn Express & Suites Jacksonville Se Med C
From$97
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Towneplace Stes East Marriott
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
13741 Beach Blvd., Jacksonville, FL 32224 ~2.09 miles northwest of Mayo Clinic
  • 3 star property
  • Fitness + Health Center
More Photos hotel room
From$90
Call BookMore Details
Hampton Inn & Suites by Hilton
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
13733 Beach Blvd., Jacksonville, FL 32224 ~2.13 miles northwest of Mayo Clinic
  • Mid-scale Suburban property
  • Fitness / Gym is on-site
More Photos Photo of Hampton Inn & Suites by Hilton
From$83
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Hampton Inn Jacksonville Beach / Mayo Clinic East : 1220 Marsh Landing Pkwy.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1220 Marsh Landing Pkwy., Jacksonville Beach, FL 32250 ~2.43 miles east of Mayo Clinic
  • 3 star Beach hotel
  • Check-in: 3:00 PM
More Photos Photo of Hampton Inn Jacksonville Beach / Mayo Clinic East
From$99
Very Good 4.5 /5 Read Reviews Call BookMore Details
Holiday Inn Express Jacksonville Beach
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1101 Beach Blvd., Jacksonville Beach, FL 32250 ~2.84 miles northeast of Mayo Clinic
  • Affordable Beach property
  • Free comp. breakfast
More Photos Exterior of Holiday Inn Express Jacksonville Beach
From$80
Very Good 4.5 /5 Review Score Call BookMore Details
Four Points by Sheraton Jacksonville Beachfront : 11 1st St. North
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
11 1st St. North, Jacksonville Beach, FL 32250 ~3.40 miles northeast of Mayo Clinic
  • 3 star Beach property
  • Check in: 3:00 pm
  • Quiet ocean front room
  • Friendly service
More Photos Image of Four Points by Sheraton Jacksonville Beachfront
From$130
Very Good 4.5 /5 Review Score Call BookMore Details
Best Western Oceanfront : 305 1st St. North
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
305 1st St. North, Jacksonville Beach, FL 32250-6908 ~3.50 miles northeast of Mayo Clinic
  • Midscale Beach hotel
  • Hotel has 3 floors
More Photos Photo of Best Western Oceanfront
From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Execustay Retreat St. Johns - Jacksonville
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
12310 Seacrest Lane, Jacksonville, FL 32224 ~3.51 miles west of Mayo Clinic
  • Mid-scale property
  • Check in: 16:00
More Photos hotel room
From$90
Call BookMore Details
Casa Marina Hotel & Restaurant - Jacksonville Beach
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
691 1st St. North, Jacksonville Beach, FL 32250 ~3.60 miles northeast of Mayo Clinic
  • Midscale Oceanfront property
  • Hotel has 16 suites
  • Modern Hotel
  • The majority of guests were satisfied with the menu
More Photos Exterior of Casa Marina Hotel & Restaurant
From$110
Average 3.5 /5 Latest Reviews Call BookMore Details
Ponte Vedra Beach Resorts - Ponte Vedra Beach
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
200 Ponte Vedra Blvd., Ponte Vedra Beach, FL 32082 ~3.78 miles east of Mayo Clinic
  • Luxury 5-star Beach hotel
  • 315 rooms in property
  • All guests thought rooms were spacious
  • Almost all guests found the grounds to be nice
More Photos Image of Ponte Vedra Beach Resorts
From$179
Very Good 4.5 /5 Read Reviews Call BookMore Details
Hampton Inn Oceanfront Jax Beach
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1515 1st St. North, Jacksonville Beach, FL 32250 ~3.91 miles northeast of Mayo Clinic
  • 3-star Oceanfront property
  • Free breakfast available
  • Most guests found problems with the furniture
  • Good bar
More Photos Image of Hampton Inn Oceanfront Jax Beach
From$119
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Jacksonville Be in Jacksonville Beach
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1616 1st St. North, Jacksonville Beach, FL 32250 ~3.92 miles northeast of Mayo Clinic
  • 3-star Beach hotel
  • 76 sleeping rooms in hotel
  • Most guests said rooms were small
  • Great burgers
More Photos Exterior of Fairfield Inn & Suites by Marriott Jacksonville Be
From$129
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Oceanfront Jacksonville Beac
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1617 1st St. North, Jacksonville Beach, FL 32250 ~3.93 miles northeast of Mayo Clinic
  • Affordable Beach hotel
  • Check in: 03:00 PM
  • Rooms need regular maintenance
  • Most guests appreciated the closeness to the beach
More Photos Exterior of Courtyard by Marriott Oceanfront Jacksonville Beac
From$159
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Red Roof Inn Neptune Beach Mayo Clinic
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1401 Atlantic Blvd., Neptune Beach, FL 32266 ~4.50 miles north of Mayo Clinic
  • Affordable Beach property
  • Free complimentary breakfast
More Photos Image of Red Roof Inn Neptune Beach Mayo Clinic
From$53
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Jacksonville Town Center in Jacksonville
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
10573 Brightman Blvd., Jacksonville, FL 32246 ~4.96 miles west of Mayo Clinic
  • Midscale Downtown hotel
  • 5 floors in property
More Photos Photo of Holiday Inn Express & Suites Jacksonville Town Center
From$89
Call BookMore Details
The Lodge & Club at Ponte Vedra Beach - Ponte Vedra Beach
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
607 Ponte Vedra Blvd., Ponte Vedra Beach, FL 32082 ~4.96 miles southeast of Mayo Clinic
  • Luxurious Five Star property
  • Fitness center on property
More Photos Image of The Lodge & Club at Ponte Vedra Beach
From$250
Very Good 4.5 /5 Latest Reviews Call BookMore Details
One Ocean Resort & Spa
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1 Ocean Blvd., Atlantic Beach, FL 32233 ~5.01 miles northeast of Mayo Clinic
  • High end Beach property
  • Fitness / Gym is on-site
  • All guests said it was a stylish hotel
  • World class service
More Photos Photo of One Ocean Resort & Spa
From$131
Very Good 4.5 /5 Reviews Call BookMore Details
Hilton Garden Inn Jacksonville / Ponte Vedra
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
45 Pga Tour Blvd., Ponte Vedra Beach, FL 32082 ~5.10 miles southeast of Mayo Clinic
  • Midscale Resort hotel
  • Check-in: 03:00 PM
  • All guests thought the service was very professional
  • World class service
More Photos Image of Hilton Garden Inn Jacksonville / Ponte Vedra
From$80
Very Good 4.5 /5 Latest Reviews Call BookMore Details
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Next: Show All Available Mayo Clinic Hotels with Pricing

Bar Chart: Upcoming 20 Days of Mayo Clinic Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Pablo Keys, FL discounts available. The chart reflects the cheapest Pablo Keys hotel for each day and each star rating category.

What are the best hotels near Mayo Clinic?

HotelDescriptionLink
1. Courtyard by Marriott Jacksonville San Pablo The Courtyard by Marriott Jacksonville San Pablo is a popular 3-Star hotel located approx. 0.1 miles southwest of Mayo Clinic and roughly a 1 minute stroll by foot. Recent hotel guests gave this hotel a verified guest score of 4/5. Get the latest price
2. Inn at Mayo Clinic The Inn at Mayo Clinic is a favored 3-Star hotel located ~0.2 mi. north of Mayo Clinic and approx. a 3 minute walk by foot. With a verified guest score of 4/5, this makes it one of the most desirable hotels nearby Mayo Clinic. Get the latest price
3. Holiday Inn Express & Suites Jacksonville Se Med C The Holiday Inn Express & Suites Jacksonville Se Med C is a popular 3 star hotel located approx. 1.7 miles west of Mayo Clinic and about a 3 min. drive. Recent guests gave this hotel an avg. guest review rating of 4 out of 5. Get the latest price
4. Hampton Inn & Suites by Hilton The Hampton Inn & Suites by Hilton is an in demand 3 star hotel located approx. 2.1 miles northwest of Mayo Clinic and approximately a 4 min. car ride. Recent travelers gave this hotel an aggregate guest review score of 4.5 out of 5. Get the latest price
5. Hampton Inn Jacksonville Beach The Hampton Inn Jacksonville Beach is a popular 3 star hotel located approx. 2.4 miles east of Mayo Clinic and about a 4 min. drive. With a guest review score of 4.5 out of 5, this makes it one of the premium properties close to Mayo Clinic. Get the latest price

5 Best Hotels near Mayo Clinic

FAQs about hotels near Mayo Clinic

What are the top reviewed hotels near Mayo Clinic?

Hampton Inn & Suites by Hilton, Hampton Inn Jacksonville Beach and Holiday Inn Express Jacksonville Beach are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near Mayo Clinic?

Ponte Vedra Beach Resorts, The Lodge & Club at Ponte Vedra Beach and One Ocean Resort & Spa are the top 3 luxury hotels near Mayo Clinic.

What hotels are closest to the area of Mayo Clinic?

Courtyard by Marriott Jacksonville San Pablo, The Inn at Mayo Clinic, and Holiday Inn Express & Suites Jacksonville Se Med C are the properties closest to Mayo Clinic.

What are the most popular independent hotels near Mayo Clinic?

Ponte Vedra Beach Resorts, The Lodge & Club at Ponte Vedra Beach and One Ocean Resort & Spa are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near Mayo Clinic?

Courtyard by Marriott Oceanfront Jacksonville Beac, Courtyard by Marriott Jacksonville San Pablo and Fairfield Inn & Suites by Marriott Jacksonville Be are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best IHG hotels near Mayo Clinic?

Holiday Inn Express Jacksonville Beach, Holiday Inn I 295 East Baymeadows and Holiday Inn Express & Suites Jacksonville Se Med C are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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