Star Rating
Hotel Name
Price Range (USD)to
Amenities

Hotels Near Mayo Clinic - Mayo Clinic Florida

Accommodations close to Mayo Clinic are shown in the list below sorted in the order of their distance (closest first). Browse our hotels to find accommodations near Mayo Clinic (Mayo Clinic) for your leisure or corporate trips.Mayo Clinic is located at 4500 San Pablo Rd S. We show the best lodging close to Mayo Clinic so you can review the available Mayo Clinic lodging below and securely book your ideal hotel.

Lodging & Accommodations close by Mayo Clinic

Courtyard by Marriott Jacksonville San Pablo
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863
14390 Mayo Blvd., Jacksonville, FL 32224 ~0.08 miles southwest of Mayo Clinic
~1 minute walk
  • 3 star Beach hotel
  • 3 floors in property
  • Clean hotel facilities
  • Most guests said the breakfast was too expensive
More PhotosImage of Courtyard by Marriott Jacksonville San Pablo
From$50
Very Good 4.0 /5Recent Reviews CallBookMore Details
The Inn at Mayo Clinic : 4420 Mary Brigh Dr.
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863
4420 Mary Brigh Dr., Jacksonville, FL 32224 ~0.24 miles north of Mayo Clinic
~4 minute walk
  • Affordable Beach hotel
  • Check in time: 3:00 PM
More Photos Exterior of The Inn at Mayo Clinic
From$99
Very Good 4.0 /5Hotel Reviews CallBookMore Details
Holiday Inn Express & Suites Jacksonville Se Med C
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863
4791 Windsor Commons Court Jacksonville Fl 3222, Jacksonville, FL 32224 ~1.71 miles west of Mayo Clinic
  • 3-star Golf Course hotel
  • Fitness center on property
  • Good selection at breakfast
  • Close to restaurants
More Photos Photo of Holiday Inn Express & Suites Jacksonville Se Med C
From$97
Very Good 4.0 /5Guest Reviews CallBookMore Details
Hampton Inn & Suites by Hilton - Jacksonville
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863
13733 Beach Blvd., Jacksonville, FL 32224 ~2.13 miles northwest of Mayo Clinic
  • Midscale Suburban hotel
  • 19 suites in property
More Photos Exterior of Hampton Inn & Suites by Hilton
From$83
Very Good 4.5 /5Reviews CallBookMore Details
Hampton Inn Jacksonville Beach / Mayo Clinic East
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863
1220 Marsh Landing Pkwy., Jacksonville Beach, FL 32250 ~2.43 miles east of Mayo Clinic
  • 3 star Beach hotel
  • 5 floors in hotel
More Photos Image of Hampton Inn Jacksonville Beach / Mayo Clinic East
From$99
Very Good 4.5 /5Recent Reviews CallBookMore Details
Holiday Inn Express Jacksonville Beach : 1101 Beach Blvd.
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863
1101 Beach Blvd., Jacksonville Beach, FL 32250 ~2.84 miles northeast of Mayo Clinic
  • 3-star Beach property
  • 3 floors in hotel
More Photos Exterior of Holiday Inn Express Jacksonville Beach
From$80
Very Good 4.5 /5Recent Reviews CallBookMore Details
Four Points by Sheraton Jacksonville Beachfront
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863
11 1st St. North, Jacksonville Beach, FL 32250 ~3.40 miles northeast of Mayo Clinic
  • Affordable Beach property
  • 2 conference rooms in property
  • Most guests enjoyed the friendly atmosphere
  • Free continental breakfast
More Photos Image of Four Points by Sheraton Jacksonville Beachfront
From$130
Very Good 4.5 /5Review Score CallBookMore Details
Best Western Oceanfront - Jacksonville Beach
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863
305 1st St. North, Jacksonville Beach, FL 32250-6908 ~3.50 miles northeast of Mayo Clinic
  • 3-star Beach property
  • 51 sleeping rooms in hotel
More Photos Image of Best Western Oceanfront
From$80
Very Good 4.0 /5Read Reviews CallBookMore Details
Execustay Retreat St. Johns : 12310 Seacrest Lane
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863
12310 Seacrest Lane, Jacksonville, FL 32224 ~3.51 miles west of Mayo Clinic
  • Affordable property
  • Check-in: 16:00
More Photos hotel room
From$90
CallBookMore Details
Casa Marina Hotel & Restaurant
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863
691 1st St. North, Jacksonville Beach, FL 32250 ~3.60 miles northeast of Mayo Clinic
  • Mid-scale Oceanfront property
  • 3 meeting rooms in hotel
  • Great food
  • Popular among couples
More Photos Image of Casa Marina Hotel & Restaurant
From$110
Average 3.5 /5Hotel Reviews CallBookMore Details
Surfside Inn
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863
1236 N.1st St., Jacksonville Beach, FL 32250 ~3.77 miles northeast of Mayo Clinic
  • Low Cost Beach property
  • Hotel has 32 rooms
More Photos Exterior of Surfside Inn
From$69
CallBookMore Details
Ponte Vedra Beach Resorts in Ponte Vedra Beach
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863
200 Ponte Vedra Blvd., Ponte Vedra Beach, FL 32082 ~3.78 miles east of Mayo Clinic
  • Luxury Five Star Beach property
  • 2 floors in hotel
  • Almost all guests found the grounds to be nice
  • All guests thought rooms were spacious
More Photos Exterior of Ponte Vedra Beach Resorts
From$179
Very Good 4.5 /5Hotel Reviews CallBookMore Details
Hampton Inn Oceanfront Jax Beach
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863
1515 1st St. North, Jacksonville Beach, FL 32250 ~3.91 miles northeast of Mayo Clinic
  • 3 star Oceanfront hotel
  • 2 conference rooms in property
  • Internet is poor
  • Delicious complimentary breakfast
More Photos Image of Hampton Inn Oceanfront Jax Beach
From$119
Very Good 4.5 /5Latest Reviews CallBookMore Details
Fairfield Inn & Suites by Marriott Jacksonville Be in Jacksonville Beach
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863
1616 1st St. North, Jacksonville Beach, FL 32250 ~3.92 miles northeast of Mayo Clinic
  • Affordable Beach property
  • Check in time: 03.00 PM
  • Fantastic customer service
  • Clean
More Photos Exterior of Fairfield Inn & Suites by Marriott Jacksonville Be
From$129
Very Good 4.0 /5Reviews CallBookMore Details
Courtyard by Marriott Oceanfront Jacksonville Beac : 1617 1st St. North
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863
1617 1st St. North, Jacksonville Beach, FL 32250 ~3.93 miles northeast of Mayo Clinic
  • 3 star Beach property
  • 7 floors in hotel
  • Great pool area
  • Great shower
More Photos Photo of Courtyard by Marriott Oceanfront Jacksonville Beac
From$159
Very Good 4.5 /5Review Score CallBookMore Details
Red Roof Inn Neptune Beach Mayo Clinic
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863
1401 Atlantic Blvd., Neptune Beach, FL 32266 ~4.50 miles north of Mayo Clinic
  • 3-star Beach hotel
  • 2 floors in property
More Photos Exterior of Red Roof Inn Neptune Beach Mayo Clinic
From$53
Average 3.0 /5Read Reviews CallBookMore Details
Holiday Inn Express & Suites Jacksonville Town Center
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863
10573 Brightman Blvd., Jacksonville, FL 32246 ~4.96 miles west of Mayo Clinic
  • Affordable property
  • Fitness + Health Center
More Photos Photo of Holiday Inn Express & Suites Jacksonville Town Center
From$80
CallBookMore Details
The Lodge & Club at Ponte Vedra Beach - Ponte Vedra Beach
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863
607 Ponte Vedra Blvd., Ponte Vedra Beach, FL 32082 ~4.96 miles southeast of Mayo Clinic
  • Luxurious 5 Star hotel
  • Check in time: 16:00
More Photos Image of The Lodge & Club at Ponte Vedra Beach
From$250
Very Good 4.5 /5Latest Reviews CallBookMore Details
One Ocean Resort & Spa - Atlantic Beach
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863
1 Ocean Blvd., Atlantic Beach, FL 32233 ~5.01 miles northeast of Mayo Clinic
  • Four-star Beach hotel
  • 193 rooms in property
  • Beautiful clean hotel on the beach
  • Smallest shower room
More Photos Photo of One Ocean Resort & Spa
From$131
Very Good 4.5 /5Latest Reviews CallBookMore Details
Hilton Garden Inn Jacksonville / Ponte Vedra
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863
45 Pga Tour Blvd., Ponte Vedra Beach, FL 32082 ~5.10 miles southeast of Mayo Clinic
  • 3 star Resort hotel
  • Check-in time: 03:00 PM
  • Room was nice and clean
  • Delicious food
More Photos Exterior of Hilton Garden Inn Jacksonville / Ponte Vedra
From$80
Very Good 4.5 /5Recent Reviews CallBookMore Details
 [1 - 20 of 25]    
Next: Show All Available Mayo Clinic Hotels with Pricing

Bar Chart: Upcoming 20 Days of Mayo Clinic Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Pablo Keys, FL discounts available. The chart reflects the cheapest Pablo Keys hotel for each day and each star rating category.

What are the best hotels near Mayo Clinic?

HotelDescriptionLink
1. Courtyard by Marriott Jacksonville San PabloThe Courtyard by Marriott Jacksonville San Pablo is a popular 3-Star hotel located approx. 0.1 miles southwest of Mayo Clinic and roughly a 1 minute stroll by foot. Recent hotel guests gave this hotel a verified guest score of 4/5.Get the latest price
2. Inn at Mayo ClinicThe Inn at Mayo Clinic is a favored 3-Star hotel located ~0.2 mi. north of Mayo Clinic and approx. a 3 minute walk by foot. With a verified guest score of 4/5, this makes it one of the most desirable hotels nearby Mayo Clinic.Get the latest price
3. Holiday Inn Express & Suites Jacksonville Se Med CThe Holiday Inn Express & Suites Jacksonville Se Med C is a popular 3 star hotel located approx. 1.7 miles west of Mayo Clinic and about a 3 min. drive. Recent guests gave this hotel an avg. guest review rating of 4 out of 5.Get the latest price
4. Hampton Inn & Suites by HiltonThe Hampton Inn & Suites by Hilton is an in demand 3 star hotel located approx. 2.1 miles northwest of Mayo Clinic and approximately a 4 min. car ride. With a aggregate guest review score of 4.5 out of 5, this makes it one of the most desirable accommodations close to Mayo Clinic.Get the latest price
5. Hampton Inn Jacksonville BeachThe Hampton Inn Jacksonville Beach is a popular 3 star hotel located approx. 2.4 miles east of Mayo Clinic and about a 4 min. drive. Recent guests gave this hotel an avg. guest review rating of 4.5 out of 5.Get the latest price

5 Best Hotels near Mayo Clinic

FAQs about hotels near Mayo Clinic

What are the top reviewed hotels near Mayo Clinic?

Hampton Inn & Suites by Hilton, Hampton Inn Jacksonville Beach and Holiday Inn Express Jacksonville Beach are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near Mayo Clinic?

Ponte Vedra Beach Resorts, The Lodge & Club at Ponte Vedra Beach and One Ocean Resort & Spa are the top 3 luxury hotels near Mayo Clinic.

What hotels are closest to the area of Mayo Clinic?

Courtyard by Marriott Jacksonville San Pablo, The Inn at Mayo Clinic, and Holiday Inn Express & Suites Jacksonville Se Med C are the properties closest to Mayo Clinic.

What are the most popular independent hotels near Mayo Clinic?

Ponte Vedra Beach Resorts, The Lodge & Club at Ponte Vedra Beach and One Ocean Resort & Spa are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near Mayo Clinic?

Courtyard by Marriott Oceanfront Jacksonville Beac, Courtyard by Marriott Jacksonville San Pablo and Fairfield Inn & Suites by Marriott Jacksonville Be are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best IHG hotels near Mayo Clinic?

Holiday Inn Express Jacksonville Beach, Holiday Inn I 295 East Baymeadows and Holiday Inn Express & Suites Jacksonville Se Med C are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Back to Top