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Hotels Near Mayo Clinic - Mayo Clinic Florida

Accommodations close to Mayo Clinic are shown in the list below sorted in the order of their distance (closest first). Browse our hotels to find accommodations near Mayo Clinic (Mayo Clinic) for your leisure or corporate trips.Mayo Clinic is located at 4500 San Pablo Rd S. We show the best lodging close to Mayo Clinic so you can review the available Mayo Clinic lodging below and securely book your ideal hotel.

Lodging/Accommodations close to Mayo Clinic

Courtyard by Marriott Jacksonville San Pablo
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 19042231700
14390 Mayo Blvd., Jacksonville, FL 32224 ~0.08 miles southwest of Mayo Clinic / ~1 minutes walking
  • 3 star Beach hotel
  • 146 rooms in hotel
  • Beach nearby
  • Good beach
More PhotosExterior of Courtyard by Marriott Jacksonville San Pablo
From$50
Very Good 4.0 /5Latest Reviews CallBookMore Details
The Inn at Mayo Clinic
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 19049929992
4420 Mary Brigh Dr., Jacksonville, FL 32224 ~0.24 miles north of Mayo Clinic / ~4 minutes walking
  • 3 star Beach property
  • 3 floors in hotel
More Photos Exterior of The Inn at Mayo Clinic
From$145
Very Good 4.0 /5Guest Reviews CallBookMore Details
Holiday Inn Express & Suites Jacksonville Se Med C in Jacksonville
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 19044217000
4791 Windsor Commons Court, Jacksonville, FL 32224 ~1.75 miles west of Mayo Clinic
  • Three Star Golf Course property
  • Hotel has 16 suites
More Photos Photo of Holiday Inn Express & Suites Jacksonville Se Med C
From$79
Very Good 4.5 /5Latest Reviews CallBookMore Details
Hampton Inn & Suites by Hilton : 13733 Beach Blvd.
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 19042230222
13733 Beach Blvd., Jacksonville, FL 32224 ~2.13 miles northwest of Mayo Clinic
  • 3 star Suburban hotel
  • Gym is available on property
More Photos Photo of Hampton Inn & Suites by Hilton
From$83
Very Good 4.5 /5Hotel Reviews CallBookMore Details
Hampton Inn Jacksonville Beach Ponte Vedra
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863 Front Desk: 19042809101
1220 Marsh Landing Pkwy., Jacksonville Beach, FL 32250 ~2.43 miles east of Mayo Clinic
  • Three Star Beach property
  • Fitness + Health Center
  • Most guests thought it was clean
  • Clean rooms
More Photos Exterior of Hampton Inn Jacksonville Beach Ponte Vedra
From$89
Very Good 4.5 /5Guest Reviews CallBookMore Details
Holiday Inn Express Jacksonville Beach : 1101 Beach Blvd.
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863 Front Desk: 19044353000
1101 Beach Blvd., Jacksonville Beach, FL 32250 ~2.84 miles northeast of Mayo Clinic
  • Midscale Beach property
  • 82 rooms in property
More Photos Image of Holiday Inn Express Jacksonville Beach
From$80
Very Good 4.5 /5Reviews CallBookMore Details
Four Points by Sheraton Jacksonville Beachfront
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 19044353535
11 1st St. North, Jacksonville Beach, FL 32250 ~3.40 miles northeast of Mayo Clinic
  • Mid-scale Beach hotel
  • 2 meeting rooms in property
  • Nearby bars and restaurants
  • Everything up to date
More Photos Photo of Four Points by Sheraton Jacksonville Beachfront
From$130
Very Good 4.5 /5Hotel Reviews CallBookMore Details
Best Western Oceanfront - Jacksonville Beach
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 19042494949
305 1st St. North, Jacksonville Beach, FL 32250 ~3.50 miles northeast of Mayo Clinic
  • Three Star Beach property
  • Hotel has an eco-friendly policy See policy
  • Friendly service
  • Vibe is not too good
More Photos Image of Best Western Oceanfront
From$125
Very Good 4.0 /5Reviews CallBookMore Details
Execustay Retreat St. Johns in Jacksonville
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 8667245487
12310 Seacrest Lane, Jacksonville, FL 32224 ~3.51 miles west of Mayo Clinic
  • Midscale property
  • 420 sleeping rooms in hotel
More Photos hotel room
From$90
CallBookMore Details
Casa Marina Hotel & Restaurant - Jacksonville Beach
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 9042700025
691 1st St. North, Jacksonville Beach, FL 32250 ~3.60 miles northeast of Mayo Clinic
  • Three Star Oceanfront hotel
  • Free breakfast
  • Good location
  • Delicious food
More Photos Image of Casa Marina Hotel & Restaurant
From$110
Average 3.5 /5Latest Reviews CallBookMore Details
Surfside Inn
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863
1236 N.1st St., Jacksonville Beach, FL 32250 ~3.77 miles northeast of Mayo Clinic
  • Economy Beach hotel
  • 2 floors in property
More Photos Photo of Surfside Inn
From$69
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Ponte Vedra Beach Resorts : 200 Ponte Vedra Blvd.
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863 Front Desk: 19042851111
200 Ponte Vedra Blvd., Ponte Vedra Beach, FL 32082 ~3.78 miles east of Mayo Clinic
  • Luxurious 5-star Beach hotel
  • Hotel has 50 suites
  • All guests thought the view was good
  • Location is great
More Photos Photo of Ponte Vedra Beach Resorts
From$189
Very Good 4.5 /5Reviews CallBookMore Details
Hampton Inn Oceanfront Jax Beach
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863 Front Desk: 19042412311
1515 1st St. North, Jacksonville Beach, FL 32250 ~3.91 miles northeast of Mayo Clinic
  • 3 star Oceanfront property
  • Hotel has 177 rooms
  • Staff in this place is amazing
  • Management is acceptable
More Photos Image of Hampton Inn Oceanfront Jax Beach
From$119
Very Good 4.5 /5Reviews CallBookMore Details
Fairfield Inn & Suites by Marriott Jacksonville Be
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 19044350300
1616 1st St. North, Jacksonville Beach, FL 32250 ~3.92 miles northeast of Mayo Clinic
  • Three Star Beach hotel
  • 3 floors in hotel
  • Most guests said the bathroom was dirty
  • We loved the location
More Photos Exterior of Fairfield Inn & Suites by Marriott Jacksonville Be
From$99
Very Good 4.0 /5Reviews CallBookMore Details
Courtyard by Marriott Oceanfront Jacksonville Beac in Jacksonville Beach
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863
1617 1st St. North, Jacksonville Beach, FL 32250 ~3.93 miles northeast of Mayo Clinic
  • Midscale Beach property
  • Hotel has 3 meeting rooms
  • Most guests liked the proximity to shopping
  • Furniture needs more attention
More Photos Image of Courtyard by Marriott Oceanfront Jacksonville Beac
From$109
Very Good 4.5 /5Hotel Reviews CallBookMore Details
Red Roof Inn Neptune Beach Mayo Clinic : 1401 Atlantic Blvd.
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 19598883000
1401 Atlantic Blvd., Neptune Beach, FL 32266 ~4.50 miles north of Mayo Clinic
  • Affordable Beach property
  • Gym is available on property
More Photos Exterior of Red Roof Inn Neptune Beach Mayo Clinic
From$42
Very Good 4.0 /5Recent Reviews CallBookMore Details
One Ocean Resort & Spa in Atlantic Beach
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 19048532346
1 Ocean Blvd., Atlantic Beach, FL 32233 ~5.01 miles northeast of Mayo Clinic
  • High-end Beach property
  • Check in: 3:00pm
  • Couldn't open the door
  • Well-appointed interior
More Photos Photo of One Ocean Resort & Spa
From$131
Very Good 4.5 /5Review Score CallBookMore Details
Hilton Garden Inn Jacksonville / Ponte Vedra
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 19042801661
45 Pga Tour Blvd., Ponte Vedra Beach, FL 32082 ~5.10 miles southeast of Mayo Clinic
  • 3 star Resort property
  • The majority of guests thought rooms were spacious
  • Huge tv
More Photos Image of Hilton Garden Inn Jacksonville / Ponte Vedra
From$80
Very Good 4.5 /5Read Reviews CallBookMore Details
Sawgrass Marriott Golf Resort & Spa - Ponte Vedra Beach
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863 Front Desk: 19042857777
1000 Pga Tour Blvd., Ponte Vedra Beach, FL 32082 ~5.15 miles southeast of Mayo Clinic
  • 4 star Beach hotel
  • 36 meeting rooms in property
  • Well maintained, beautiful property
  • Average sized rooms
More Photos Image of Sawgrass Marriott Golf Resort & Spa
From$129
Very Good 4.0 /5Guest Reviews CallBookMore Details
Holiday Inn East I 295 & Baymeadows in Jacksonville
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863 Front Desk: 19048548000
11083 Nurseryfields Dr., Jacksonville, FL 32256 ~5.34 miles southwest of Mayo Clinic
  • 3-star Suburban hotel
  • Hotel has 4 meeting rooms
  • Most guests found the staff to be very friendly
  • Most guests enjoyed the restaurants & bars nearby
More Photos Exterior of Holiday Inn East I 295 & Baymeadows
From$86
Very Good 4.5 /5Latest Reviews CallBookMore Details
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Next: Show All Available Mayo Clinic Hotels with Pricing

Chart of the best hotels near Mayo Clinic

HotelDescriptionLink
1. Courtyard by Marriott Jacksonville San PabloThe Courtyard by Marriott Jacksonville San Pablo is a popular 3-Star hotel located approx. 0.1 miles southwest of Mayo Clinic and roughly a 1 minute stroll by foot. Recent hotel guests gave this hotel a verified guest score of 4/5.Get the latest price
2. Inn at Mayo ClinicThe Inn at Mayo Clinic is a favored 3-Star hotel located ~0.2 mi. north of Mayo Clinic and approx. a 3 minute walk by foot. With a verified guest score of 4/5, this makes it one of the most desirable hotels nearby Mayo Clinic.Get the latest price
3. Holiday Inn Express & Suites Jacksonville Se Med CThe Holiday Inn Express & Suites Jacksonville Se Med C is a well-liked 3-Star hotel located about 1.8 miles west of Mayo Clinic and roughly a 3 minute drive or taxi ride. Recent hotel guests gave this hotel a guest review score of 4.5/5.Get the latest price
4. Hampton Inn & Suites by HiltonThe Hampton Inn & Suites by Hilton is an in demand 3 star hotel located approx. 2.1 miles northwest of Mayo Clinic and approximately a 4 min. car ride. With a aggregate guest review score of 4.5 out of 5, this makes it one of the most desirable accommodations close to Mayo Clinic.Get the latest price
5. Hampton Inn Jacksonville Beach Ponte VedraThe Hampton Inn Jacksonville Beach Ponte Vedra is a leading 3 star hotel located approx. 2.4 miles east of Mayo Clinic and about a 4 min. drive or uber ride. Recent guests gave this hotel a verified guest score of 4.5 out of 5.Get the latest price

5 Best Hotels near Mayo Clinic

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