Accommodations close to Mayo Clinic are shown in the list below sorted in the order of their distance (closest first). Browse our hotels to find accommodations near Mayo Clinic (Mayo Clinic) for your leisure or corporate trips.
Mayo Clinic is located at 4500 San Pablo Rd S. We show the best lodging close to Mayo Clinic so you can review the available Mayo Clinic lodging below and securely book your ideal hotel.
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Hampton Inn & Suites by Hilton, Hampton Inn Jacksonville Beach and Holiday Inn Express Jacksonville Beach are the best rated hotels based on customer reviews in the last 365 days.
Ponte Vedra Beach Resorts, The Lodge & Club at Ponte Vedra Beach and One Ocean Resort & Spa are the top 3 luxury hotels near Mayo Clinic.
Courtyard by Marriott Jacksonville San Pablo, The Inn at Mayo Clinic, and Holiday Inn Express & Suites Jacksonville Se Med C are the properties closest to Mayo Clinic.
Ponte Vedra Beach Resorts, The Lodge & Club at Ponte Vedra Beach and One Ocean Resort & Spa are the best rated independent hotels (not part of a big brand).
Courtyard by Marriott Oceanfront Jacksonville Beac, Courtyard by Marriott Jacksonville San Pablo and Fairfield Inn & Suites by Marriott Jacksonville Be are the best rated Marriott/Starwood branded hotels (based on customer reviews score).
Holiday Inn Express Jacksonville Beach, Holiday Inn I 295 East Baymeadows and Holiday Inn Express & Suites Jacksonville Se Med C are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).