Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels & Accommodations

Super 8 by Wyndham Greenville : 1700 State Route 127 1700 State Route 127, Greenville, IL 62246 Call
  • Inexpensive Rural property
  • Free comp. breakfast
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From$60
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SureStay by Best Western Greenville 1731 South State Route 127, Greenville, IL 62246 Call
  • Low priced Highway hotel
  • 2 floors in hotel
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From$42
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Comfort Inn & Suites Greenville I-70 in Greenville 2265 South State Route 127, Greenville, IL 62246 Website Call
  • Cheap Rural hotel
  • Gym is available on property
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From$53
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Vandalia Il - Vandalia 21 Mattes Ave., Vandalia, IL 62471 Call ~15.52 miles east of Greenville
  • Affordable Highway hotel
  • Check-in: 3:00 PM
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From$80
Average 3.0 /5 Review Score Call BookMore Details
Ramada by Wyndham Vandalia 2707 Veterans Ave., Vandalia, IL 62471 Call ~15.77 miles east of Greenville
  • Inexpensive hotel
  • Check in: 11:00 AM
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From$60
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Americas Best Value Inn Vandalia 1500 North 6th St., Vandalia, IL 62471 Call ~17.45 miles east of Greenville
  • Low Cost Lake hotel
  • Check-in time: 3.00
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From$50
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Quality Inn & Suites Vandalia near I-70 and Hwy 51 - Vandalia 1920 North Kennedy Blvd., Vandalia, IL 62471 Website Call ~17.57 miles east of Greenville
  • Cheap Highway hotel
  • Complimentary breakfast is offered
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From$60
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Quality Inn & Suites Vandalia near I-70 and Hwy 51 1920 Kennedy Blvd., Vandalia, IL 62471 Call ~17.59 miles east of Greenville
  • Economical Rural hotel
  • Hotel has 85 rooms
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From$57
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Seasons Inn & Suites Highland : 20 Central Blvd. 20 Central Blvd., Highland, IL 62249 Call ~17.74 miles southwest of Greenville
  • Economical hotel
  • Check-in time: 3:00 PM
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From$65
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Mariner's Village Resort & Inn : 1 Resort Dr. 1 Resort Dr., Carlyle, IL 62231 Call ~18.34 miles south of Greenville
  • Cheap Lake property
  • Hotel has 65 rooms
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From$59
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Centerstone Inn & Suites - Carlyle 1371 William Rd., Carlyle, IL 62231 Call ~18.46 miles south of Greenville
  • Economy property
  • Comp. Breakfast
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From$60
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Super 8 by Wyndham Staunton 1527 Herman Rd., Staunton, IL 62088 Call ~21.09 miles west of Greenville
  • Low-priced hotel
  • 50 rooms in hotel
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From$50
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Innkeeper Motel : 401 East State St. 401 East State St., Hamel, IL 62046 Call ~23.07 miles west of Greenville
  • Three Star Lake hotel
  • Check in: 2:00 PM
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From$80
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Americas Best Value Inn Litchfield - Litchfield 224 North Ohren Lane, Litchfield, IL 62056 Call ~24.10 miles northwest of Greenville
  • Low priced property
  • Check-in: 15:00
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From$60
Poor 2.0 /5 Reviews Call BookMore Details
Motel 6 Litchfield, IL - Litchfield 211 Ohren Ln, Litchfield, IL 62056 Call ~24.16 miles northwest of Greenville
  • Inexpensive Highway property
  • Check in time: 11:00 AM
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From$60
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Baymont by Wyndham Litchfield : 1405 West Hudson Dr. 1405 West Hudson Dr., Litchfield, IL 62056 Call ~24.16 miles northwest of Greenville
  • Low-priced Highway property
  • Hotel has an eco-friendly policy Read more
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From$60
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Quality Inn Litchfield Route 66 1010 East Columbian Blvd. North, Litchfield, IL 62056 Website Call ~24.37 miles northwest of Greenville
  • Cheap Downtown property
  • 3 floors in hotel
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From$70
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Hampton Inn Litchfield 11 Thunderbird Cir, Litchfield, IL 62056 Call ~24.48 miles northwest of Greenville
  • Mid-scale Highway hotel
  • Check-in: 3:00pm
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From$80
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Holiday Inn Express & Suites Litchfield West by IHG : 4 Thunderbird Circle 4 Thunderbird Circle, Litchfield, IL 62056 Call ~24.49 miles northwest of Greenville
  • Three Star Rural hotel
  • Check-in time: 15:00
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From$79
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Best Western Plus Centralia Hotel & Suites 8145 Jolliff Bridge Rd., Centralia, IL 62801 Call ~28.09 miles southeast of Greenville
  • Three Star property
  • Hotel has 4 floors
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From$78
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Americas Best Value Inn 200 East Noleman, Centralia, IL 62801 Call ~29.09 miles southeast of Greenville
  • 2-star property
  • Free breakfast available
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From$60
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Motel 6 Troy Il in Troy 909 Edwardsville Rd., Troy, IL 62294 Call ~29.31 miles west of Greenville
  • Two star hotel
  • Check-in time: 15:00
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From$50
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Quality Inn & Suites Salem near I-57 : 1800 West Main St. 1800 West Main St., Salem, IL 62881 Website Call ~29.38 miles southeast of Greenville
  • Inexpensive Rural hotel
  • 20 suites in property
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From$69
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Best Western Troy Hotel - Troy 2020 Formosa Rd., Troy, IL 62294 Call ~29.44 miles west of Greenville
  • 3-star Rural hotel
  • Check in: 03:00 PM
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From$60
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Holiday Inn Express Troy by IHG 2011 Formosa Rd., Troy, IL 62294 Call ~29.51 miles west of Greenville
  • 3 star Highway hotel
  • Has environment-friendly policy See policy
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From$84
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Red Roof Inn St Louis - Troy, IL 2030 Formosa Rd., Troy, IL 62294 Call ~29.55 miles west of Greenville
  • Low-priced hotel
  • 8 suites in hotel
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From$53
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Salem, Illinois 1812 West Main St., Salem, IL 62881 Call ~29.55 miles southeast of Greenville
  • Two-star hotel
  • 94 rooms in property
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From$47
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Super 8 by Wyndham Troy IL/St. Louis Area 910 Edwardsville Rd., Troy, IL 62294 Call ~29.60 miles west of Greenville
  • Inexpensive Highway hotel
  • 2 floors in property
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From$63
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Super 8 by Wyndham Salem : 118 Woods Ln 118 Woods Ln, Salem, IL 62881 Call ~29.63 miles southeast of Greenville
  • Inexpensive Highway property
  • 3 floors in hotel
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From$60
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Magnuson Grand Hotel And Conference Center 19067 West Frontage Rd., Raymond, IL 62560 Call ~29.70 miles northwest of Greenville
  • 3-star Rural hotel
  • Complimentary breakfast is offered
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From$49
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Salem by IHG - Salem 102 Holiday Lane, Salem, IL 62881 Call ~29.89 miles southeast of Greenville
  • Affordable Highway property
  • Free breakfast
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From$87
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Holiday Inn Express & Suites Edwardsville by IHG : 1000 Plummer Dr. 1000 Plummer Dr., Edwardsville, IL 62025 Call ~31.59 miles west of Greenville
  • Midscale Suburban hotel
  • Complimentary breakfast is offered
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From$94
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Country Hearth Inn & Suites Edwardsville St. Louis in Edwardsville 1013 Plummer Dr., Edwardsville, IL 62025 Call ~31.66 miles west of Greenville
  • Affordable Rural property
  • Free breakfast
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From$67
Very Good 4.0 /5 Reviews Call BookMore Details
TownePlace Suites by Marriott St. Louis Edwardsville, IL in Edwardsville 6101 Center Grove Rd., Edwardsville, IL 62025 Call ~31.67 miles west of Greenville
  • Affordable Suburban hotel
  • Hotel has 91 rooms
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From$90
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Best Western Plus MidAmerica Hotel : 9730 Hayden Dr. 9730 Hayden Dr., Mascoutah, IL 62258 Call ~32.05 miles southwest of Greenville
  • Mid-scale Suburban hotel
  • Free complimentary breakfast
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From$69
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Super 8 by Wyndham Okawville 812 North Henhouse Rd., Okawville, IL 62271 Call ~32.28 miles south of Greenville
  • 2-star Rural property
  • Hotel has 2 floors
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From$64
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Super 8 by Wyndham Okawville in Okawville 812 North Hen House Rd., Okawville, IL 62271 Call ~32.28 miles south of Greenville
  • Economical property
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From$60
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Super 8 by Wyndham O'fallon : 1100 Eastgate Dr. 1100 Eastgate Dr., Ofallon, IL 62269 Call ~33.41 miles southwest of Greenville
  • Two star Suburban hotel
  • Hotel has a green policy Learn more
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From$40
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Comfort Inn Edwardsville - St. Louis - Edwardsville 3080 South State Rte 157, Edwardsville, IL 62025 Call ~33.44 miles west of Greenville
  • Two star Highway hotel
  • Check in time: 03:00 PM
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From$60
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Comfort Inn Edwardsville - Edwardsville 3080 Il 157, Edwardsville, IL 62025 Call ~33.44 miles west of Greenville
  • Midscale Highway property
  • 74 rooms in property
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From$80
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Hampton Inn & Suites St. Louis Edwardsville 5723 Heritage Crossing Dr., Glen Carbon, IL 62034 Call ~33.74 miles west of Greenville
  • Affordable Suburban hotel
  • Free comp. breakfast
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From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Best Western U. S. Inn : 11640 State Route 127 11640 State Route 127, Nashville, IL 62263 Call ~35.22 miles south of Greenville
  • Mid-scale Highway property
  • 48 rooms in hotel
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From$64
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Sleep Inn O Fallon Il 140 Venita Dr., O'fallon, IL 62269 Call ~35.35 miles southwest of Greenville
  • 3-star Suburban hotel
  • Check-in: 4:00pm
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From$80
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Holiday Inn Express & Suites O'fallon / Shiloh An Ihg Hotel : 3396 Green Mount Crossing 3396 Green Mount Crossing, Shiloh, IL 62269 Call ~35.48 miles southwest of Greenville
  • 3 star Highway property
  • Check in time: 3:00
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From$99
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Comfort Inn & Suites Ofallon St. Louis Area 116 Regency Park, O'fallon, IL 62269 Call ~35.51 miles southwest of Greenville
  • Low Cost Suburban hotel
  • 3 floors in property
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From$60
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Hampton Inn O'fallon Il - O'fallon 430 Regency Park, O'fallon, IL 62269 Call ~35.57 miles southwest of Greenville
  • 3 star Suburban property
  • Check in: 3:00pm
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From$80
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La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis 136 Regency Park, O'fallon, IL 62269 Call ~35.59 miles southwest of Greenville
  • Low-priced Suburban property
  • Hotel has 63 rooms
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From$60
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Hilton Garden Inn St. Louis Shiloh / O'fallon Il 360 Regency Park, O'fallon, IL 62269 Call ~35.65 miles southwest of Greenville
  • Three Star Suburban hotel
  • Gym / Fitness Center Available
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From$80
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Extended Stay America Select Suites - St. Louis - O' Fallon, IL 154 Regency Park, O'fallon, IL 62269 Call ~35.68 miles southwest of Greenville
  • Economy Highway property
  • Check in time: 3:00 PM
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From$39
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Drury Inn St. Louis Collinsville : 602 North Bluff Rd. 602 North Bluff Rd., Collinsville, IL 62234 Call ~35.68 miles west of Greenville
  • 3-star Suburban hotel
  • Hotel has 3 meeting rooms
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From$90
Very Good 4.0 /5 Read Reviews Call BookMore Details

Next: See My Greenville Hotels with Pricing

Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Quiet town"
Score 4.0 / 5

Quiet town and my Son plays Basketball for Greenville university.

Newton A., from 26-Feb-2026
"Great Diner!"
Score 4.0 / 5

Vicky's Cafe was awesome!! Very helpful and polite staff! Clean diner with great food!

Amy S., from 24-Aug-2025
"Dressed up Strip area."
Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025
"Quiet Area"
Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024
"Proximity to Carlyle"
Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024
"Greenville has some excellent museums!"
Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023
"Great Aquarium"
Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023
"College Campus"
Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023
"Loved It!"
Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022
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