Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels/Accommodations

Super 8 by Wyndham Greenville 1700 State Route 127, Greenville, IL 62246 Call
  • Low-priced Rural property
  • Free breakfast
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From$60
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SureStay by Best Western Greenville 1731 South State Route 127, Greenville, IL 62246 Call
  • Cheap Highway property
  • 2 floors in hotel
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From$41
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Comfort Inn & Suites Greenville I-70 2265 South State Route 127, Greenville, IL 62246 Website Call
  • Economy Rural hotel
  • Check-in time: 3:00 PM
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From$53
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Vandalia Il 21 Mattes Ave., Vandalia, IL 62471 Call ~15.52 miles east of Greenville
  • 3-star Highway property
  • 70 sleeping rooms in hotel
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Ramada by Wyndham Vandalia in Vandalia 2707 Veterans Ave., Vandalia, IL 62471 Call ~15.77 miles east of Greenville
  • Two-star property
  • Check-in time: 11:00 AM
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From$60
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Americas Best Value Inn Vandalia 1500 North 6th St., Vandalia, IL 62471 Call ~17.45 miles east of Greenville
  • Cheap Lake hotel
  • Check in: 3.00
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From$50
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Quality Inn & Suites Vandalia near I-70 and Hwy 51 1920 North Kennedy Blvd., Vandalia, IL 62471 Website Call ~17.57 miles east of Greenville
  • Cheap Highway hotel
  • Hotel has an eco-friendly policy See policy
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From$60
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 1920 Kennedy Blvd., Vandalia, IL 62471 Call ~17.59 miles east of Greenville
  • Low priced Rural hotel
  • Check in time: 2:00 p.m.
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From$57
Very Good 4.5 /5 Review Score Call BookMore Details
Seasons Inn & Suites Highland in Highland 20 Central Blvd., Highland, IL 62249 Call ~17.74 miles southwest of Greenville
  • Low Cost hotel
  • Check in time: 3:00 PM
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From$65
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Mariner's Village Resort & Inn 1 Resort Dr., Carlyle, IL 62231 Call ~18.34 miles south of Greenville
  • Economical Lake hotel
  • Hotel has 65 rooms
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From$59
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Centerstone Inn & Suites in Carlyle 1371 William Rd., Carlyle, IL 62231 Call ~18.46 miles south of Greenville
  • Cheap hotel
  • Hotel has 41 rooms
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From$60
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Super 8 by Wyndham Staunton 1527 Herman Rd., Staunton, IL 62088 Call ~21.09 miles west of Greenville
  • Cheap hotel
  • Hotel has 50 rooms
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From$50
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Innkeeper Motel : 401 East State St. 401 East State St., Hamel, IL 62046 Call ~23.07 miles west of Greenville
  • 3-star Lake hotel
  • Check in: 2:00 PM
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From$80
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Americas Best Value Inn Litchfield 224 North Ohren Lane, Litchfield, IL 62056 Call ~24.10 miles northwest of Greenville
  • Cheap property
  • Free complimentary breakfast
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From$60
Poor 2.0 /5 Recent Reviews Call BookMore Details
Motel 6 Litchfield, IL 211 Ohren Ln, Litchfield, IL 62056 Call ~24.16 miles northwest of Greenville
  • Economy Highway property
  • Check in: 11:00 AM
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From$60
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Baymont by Wyndham Litchfield 1405 West Hudson Dr., Litchfield, IL 62056 Call ~24.16 miles northwest of Greenville
  • Two-star Highway property
  • Hotel has 5 suites
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From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Quality Inn Litchfield Route 66 1010 East Columbian Blvd. North, Litchfield, IL 62056 Website Call ~24.37 miles northwest of Greenville
  • Two star Downtown hotel
  • 60 rooms in property
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From$70
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Hampton Inn Litchfield 11 Thunderbird Cir, Litchfield, IL 62056 Call ~24.48 miles northwest of Greenville
  • Affordable Highway hotel
  • 9 suites in hotel
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From$80
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Holiday Inn Express & Suites Litchfield West by IHG - Litchfield 4 Thunderbird Circle, Litchfield, IL 62056 Call ~24.49 miles northwest of Greenville
  • Three Star Rural hotel
  • 4 floors in hotel
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From$79
Very Good 4.0 /5 Review Score Call BookMore Details
Best Western Plus Centralia Hotel & Suites : 8145 Jolliff Bridge Rd. 8145 Jolliff Bridge Rd., Centralia, IL 62801 Call ~28.09 miles southeast of Greenville
  • Three Star hotel
  • Free breakfast
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From$78
Very Good 4.0 /5 Review Score Call BookMore Details
Americas Best Value Inn 200 East Noleman, Centralia, IL 62801 Call ~29.09 miles southeast of Greenville
  • Economy property
  • Check in: 2:00 PM
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From$60
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Motel 6 Troy Il in Troy 909 Edwardsville Rd., Troy, IL 62294 Call ~29.31 miles west of Greenville
  • Low priced property
  • Check-in: 15:00
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From$50
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Quality Inn & Suites Salem near I-57 : 1800 West Main St. 1800 West Main St., Salem, IL 62881 Website Call ~29.38 miles southeast of Greenville
  • Two star Rural property
  • 65 rooms in property
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From$69
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Best Western Troy Hotel 2020 Formosa Rd., Troy, IL 62294 Call ~29.44 miles west of Greenville
  • 3 star Rural property
  • Comp. Breakfast
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From$60
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Holiday Inn Express Troy by IHG 2011 Formosa Rd., Troy, IL 62294 Call ~29.51 miles west of Greenville
  • Three Star Highway property
  • Check in time: 3:00 PM
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From$84
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Red Roof Inn St Louis - Troy, IL : 2030 Formosa Rd. 2030 Formosa Rd., Troy, IL 62294 Call ~29.55 miles west of Greenville
  • Two star hotel
  • Check in time: 3:00pm
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From$53
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Days Inn by Wyndham Salem, Illinois 1812 West Main St., Salem, IL 62881 Call ~29.55 miles southeast of Greenville
  • Cheap property
  • 94 rooms in property
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From$47
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Super 8 by Wyndham Troy IL/St. Louis Area : 910 Edwardsville Rd. 910 Edwardsville Rd., Troy, IL 62294 Call ~29.60 miles west of Greenville
  • Cheap Highway hotel
  • 2 floors in property
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From$63
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Super 8 by Wyndham Salem in Salem 118 Woods Ln, Salem, IL 62881 Call ~29.63 miles southeast of Greenville
  • Inexpensive Highway hotel
  • Hotel has 3 floors
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From$60
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Magnuson Grand Hotel And Conference Center - Raymond 19067 West Frontage Rd., Raymond, IL 62560 Call ~29.70 miles northwest of Greenville
  • 3 star Rural hotel
  • Free comp. breakfast
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From$49
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Salem by IHG : 102 Holiday Lane 102 Holiday Lane, Salem, IL 62881 Call ~29.89 miles southeast of Greenville
  • 3-star Highway property
  • Comp. Breakfast
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From$87
Excellent 5.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Edwardsville by IHG : 1000 Plummer Dr. 1000 Plummer Dr., Edwardsville, IL 62025 Call ~31.59 miles west of Greenville
  • Affordable Suburban property
  • 18 suites in hotel
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From$94
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Country Hearth Inn & Suites Edwardsville St. Louis - Edwardsville 1013 Plummer Dr., Edwardsville, IL 62025 Call ~31.66 miles west of Greenville
  • Affordable Rural hotel
  • Fitness center on property
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From$67
Very Good 4.0 /5 Guest Reviews Call BookMore Details
TownePlace Suites by Marriott St. Louis Edwardsville, IL : 6101 Center Grove Rd. 6101 Center Grove Rd., Edwardsville, IL 62025 Call ~31.67 miles west of Greenville
  • 3-star Suburban property
  • Hotel has 91 rooms
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From$90
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Best Western Plus MidAmerica Hotel : 9730 Hayden Dr. 9730 Hayden Dr., Mascoutah, IL 62258 Call ~32.05 miles southwest of Greenville
  • 3 star Suburban property
  • 15 suites in hotel
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From$69
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Super 8 by Wyndham Okawville 812 North Henhouse Rd., Okawville, IL 62271 Call ~32.28 miles south of Greenville
  • Two-star Rural property
  • Hotel has 2 floors
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From$64
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Super 8 by Wyndham Okawville - Okawville 812 North Hen House Rd., Okawville, IL 62271 Call ~32.28 miles south of Greenville
  • Economical property
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From$60
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Super 8 by Wyndham O'fallon in Ofallon 1100 Eastgate Dr., Ofallon, IL 62269 Call ~33.41 miles southwest of Greenville
  • Economy Suburban hotel
  • Fitness center on property
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From$40
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Comfort Inn Edwardsville - St. Louis in Edwardsville 3080 South State Rte 157, Edwardsville, IL 62025 Website Call ~33.44 miles west of Greenville
  • 2-star Highway hotel
  • Check-in: 03:00 PM
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From$60
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Hampton Inn & Suites St. Louis Edwardsville : 5723 Heritage Crossing Dr. 5723 Heritage Crossing Dr., Glen Carbon, IL 62034 Call ~33.74 miles west of Greenville
  • Mid-scale Suburban hotel
  • Fitness center on property
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From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Best Western U. S. Inn : 11640 State Route 127 11640 State Route 127, Nashville, IL 62263 Call ~35.22 miles south of Greenville
  • 3-star Highway hotel
  • 2 floors in property
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From$62
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Sleep Inn O Fallon Il 140 Venita Dr., O'fallon, IL 62269 Call ~35.35 miles southwest of Greenville
  • Mid-scale Suburban hotel
  • 3 floors in property
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From$80
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Holiday Inn Express & Suites O'fallon / Shiloh by IHG in Shiloh 3396 Green Mt. Crossing Dr., Shiloh, IL 62269 Call ~35.49 miles southwest of Greenville
  • Three Star Highway hotel
  • Access to gym on-site
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From$80
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Comfort Inn & Suites Ofallon St. Louis Area : 116 Regency Park 116 Regency Park, O'fallon, IL 62269 Call ~35.51 miles southwest of Greenville
  • Two star Suburban hotel
  • Comp. Breakfast
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From$60
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Hampton Inn O'fallon Il 430 Regency Park, O'fallon, IL 62269 Call ~35.57 miles southwest of Greenville
  • Three Star Suburban property
  • Hotel has 100 rooms
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From$80
Very Good 4.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis in O'fallon 136 Regency Park, O'fallon, IL 62269 Call ~35.59 miles southwest of Greenville
  • Inexpensive Suburban property
  • Check in time: 3:00 PM
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From$60
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Hilton Garden Inn St. Louis Shiloh / O'fallon Il 360 Regency Park, O'fallon, IL 62269 Call ~35.65 miles southwest of Greenville
  • Three Star Suburban property
  • Check-in time: 03:00 PM
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From$80
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Extended Stay America Select Suites - St. Louis - O' Fallon, IL in O'fallon 154 Regency Park, O'fallon, IL 62269 Call ~35.68 miles southwest of Greenville
  • Two-star Highway hotel
  • 89 sleeping rooms in hotel
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From$39
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Welcome Suites 148 Regency Park, O'fallon, IL 62269 Call ~35.68 miles southwest of Greenville
  • 2-star Suburban property
  • Fitness center on property
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From$40
Very Good 4.0 /5 Reviews Call BookMore Details
Towneplace Place Suites by Marriott St. Louis O Fallon Illinois 445 Regency Park Dr., Ofallon, IL 62269 Call ~35.68 miles southwest of Greenville
  • 3 star hotel
  • 89 suites in property
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From$90
Very Good 4.0 /5 Latest Reviews Call BookMore Details

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Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Great Diner!"
Score 4.0 / 5

Vicky's Cafe was awesome!! Very helpful and polite staff! Clean diner with great food!

Amy S., from 24-Aug-2025
"Dressed up Strip area."
Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025
"Quiet Area"
Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024
"Proximity to Carlyle"
Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024
"Greenville has some excellent museums!"
Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023
"Great Aquarium"
Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023
"College Campus"
Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023
"Loved It!"
Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022
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