Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels/Motels & Accommodations

Super 8 by Wyndham Greenville : 1700 State Route 127 1700 State Route 127, Greenville, IL 62246 Call
  • Two-star Rural hotel
  • Free comp. breakfast
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From$72 total
Average 3.0 /5 Recent Reviews Call BookMore Details
SureStay by Best Western Greenville 1731 South State Route 127, Greenville, IL 62246 Call
  • 2 star Highway property
  • Check in time: 04:00
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From$49 total
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Inn & Suites Greenville I-70 2265 South State Route 127, Greenville, IL 62246 Website Call
  • Inexpensive Rural property
  • Fitness + Health Center
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From$63 total
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Vandalia Il 21 Mattes Ave., Vandalia, IL 62471 Call ~15.52 miles east of Greenville
  • Three Star Highway hotel
  • Hotel has a green policy Learn more
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From$96 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Ramada by Wyndham Vandalia 2707 Veterans Ave., Vandalia, IL 62471 Call ~15.77 miles east of Greenville
  • Economical property
  • Check-in: 11:00 AM
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From$72 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn Vandalia : 1500 North 6th St. 1500 North 6th St., Vandalia, IL 62471 Call ~17.45 miles east of Greenville
  • Two star Lake hotel
  • 2 floors in hotel
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From$60 total
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 1920 North Kennedy Blvd., Vandalia, IL 62471 Website Call ~17.57 miles east of Greenville
  • Two-star Highway property
  • Check-in: 2:00 AM
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From$72 total
Very Good 4.0 /5 Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 : 1920 Kennedy Blvd. 1920 Kennedy Blvd., Vandalia, IL 62471 Call ~17.59 miles east of Greenville
  • Cheap Rural hotel
  • Hotel has an eco-friendly policy See policy
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From$68 total
Very Good 4.5 /5 Read Reviews Call BookMore Details
Seasons Inn & Suites Highland 20 Central Blvd., Highland, IL 62249 Call ~17.74 miles southwest of Greenville
  • Economy hotel
  • Free complimentary breakfast
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From$78 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Mariner's Village Resort & Inn - Carlyle 1 Resort Dr., Carlyle, IL 62231 Call ~18.34 miles south of Greenville
  • 2 star Lake property
  • Check in: 15:00
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From$70 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Centerstone Inn & Suites 1371 William Rd., Carlyle, IL 62231 Call ~18.46 miles south of Greenville
  • 2 star hotel
  • 2 floors in hotel
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From$72 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Staunton : 1527 Herman Rd. 1527 Herman Rd., Staunton, IL 62088 Call ~21.09 miles west of Greenville
  • Economy hotel
  • 2 floors in hotel
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From$60 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Innkeeper Motel - Hamel 401 East State St., Hamel, IL 62046 Call ~23.07 miles west of Greenville
  • Affordable Lake property
  • Check in time: 2:00 PM
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From$96 total
Average 3.0 /5 Read Reviews Call BookMore Details
Americas Best Value Inn Litchfield - Litchfield 224 North Ohren Lane, Litchfield, IL 62056 Call ~24.10 miles northwest of Greenville
  • Two-star property
  • Free breakfast available
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From$72 total
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Litchfield, IL in Litchfield 211 Ohren Ln, Litchfield, IL 62056 Call ~24.16 miles northwest of Greenville
  • Cheap Highway hotel
  • Check in: 11:00 AM
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From$72 total
Average 3.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Litchfield 1405 West Hudson Dr., Litchfield, IL 62056 Call ~24.16 miles northwest of Greenville
  • Inexpensive Highway hotel
  • Hotel has 3 floors
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From$72 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Quality Inn Litchfield Route 66 - Litchfield 1010 East Columbian Blvd. North, Litchfield, IL 62056 Website Call ~24.37 miles northwest of Greenville
  • Economy Downtown property
  • Hotel has 3 floors
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From$84 total
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Hampton Inn Litchfield in Litchfield 11 Thunderbird Cir, Litchfield, IL 62056 Call ~24.48 miles northwest of Greenville
  • Midscale Highway hotel
  • Hotel has 3 floors
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From$96 total
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Litchfield West by IHG - Litchfield 4 Thunderbird Circle, Litchfield, IL 62056 Call ~24.49 miles northwest of Greenville
  • 3 star Rural property
  • Hotel has 4 floors
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From$94 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Best Western Plus Centralia Hotel & Suites in Centralia 8145 Jolliff Bridge Rd., Centralia, IL 62801 Call ~28.09 miles southeast of Greenville
  • Three Star property
  • Complimentary breakfast is offered
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From$93 total
Very Good 4.0 /5 Reviews Call BookMore Details
Americas Best Value Inn 200 East Noleman, Centralia, IL 62801 Call ~29.09 miles southeast of Greenville
  • Low priced property
  • 4 floors in property
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From$72 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Motel 6 Troy Il - Troy 909 Edwardsville Rd., Troy, IL 62294 Call ~29.31 miles west of Greenville
  • Inexpensive property
  • Hotel has 2 floors
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From$60 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites Salem near I-57 1800 West Main St., Salem, IL 62881 Website Call ~29.38 miles southeast of Greenville
  • Low Cost Rural property
  • 20 suites in property
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From$82 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Best Western Troy Hotel 2020 Formosa Rd., Troy, IL 62294 Call ~29.44 miles west of Greenville
  • Mid-scale Rural property
  • 65 sleeping rooms in hotel
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From$72 total
Average 3.5 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Troy by IHG - Troy 2011 Formosa Rd., Troy, IL 62294 Call ~29.51 miles west of Greenville
  • 3-star Highway hotel
  • 2 conference rooms in property
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From$100 total
Very Good 4.5 /5 Reviews Call BookMore Details
Red Roof Inn St Louis - Troy, IL in Troy 2030 Formosa Rd., Troy, IL 62294 Call ~29.55 miles west of Greenville
  • 2 star hotel
  • Fitness / Gym is on-site
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From$63 total
Very Good 4.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Salem, Illinois - Salem 1812 West Main St., Salem, IL 62881 Call ~29.55 miles southeast of Greenville
  • Inexpensive hotel
  • Check in time: 3:00pm
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From$56 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Troy IL/St. Louis Area : 910 Edwardsville Rd. 910 Edwardsville Rd., Troy, IL 62294 Call ~29.60 miles west of Greenville
  • Economy Highway property
  • Check in time: 03:00 PM
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From$75 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Salem 118 Woods Ln, Salem, IL 62881 Call ~29.63 miles southeast of Greenville
  • 2-star Highway property
  • Check-in: 3:00pm
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From$72 total
Average 3.0 /5 Review Score Call BookMore Details
Magnuson Grand Hotel And Conference Center - Raymond 19067 West Frontage Rd., Raymond, IL 62560 Call ~29.70 miles northwest of Greenville
  • 3 star Rural hotel
  • Hotel has an eco-friendly policy See policy
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From$58 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Salem by IHG in Salem 102 Holiday Lane, Salem, IL 62881 Call ~29.89 miles southeast of Greenville
  • Midscale Highway hotel
  • 86 rooms in hotel
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From$104 total
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Edwardsville by IHG in Edwardsville 1000 Plummer Dr., Edwardsville, IL 62025 Call ~31.59 miles west of Greenville
  • Mid-scale Suburban hotel
  • Check-in time: 3:00 PM
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From$112 total
Very Good 4.0 /5 Review Score Call BookMore Details
Country Hearth Inn & Suites Edwardsville St. Louis in Edwardsville 1013 Plummer Dr., Edwardsville, IL 62025 Call ~31.66 miles west of Greenville
  • Midscale Rural property
  • Hotel has 39 rooms
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From$80 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
TownePlace Suites by Marriott St. Louis Edwardsville, IL 6101 Center Grove Rd., Edwardsville, IL 62025 Call ~31.67 miles west of Greenville
  • 3-star Suburban property
  • Gym is available on property
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From$108 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Best Western Plus MidAmerica Hotel 9730 Hayden Dr., Mascoutah, IL 62258 Call ~32.05 miles southwest of Greenville
  • Midscale Suburban property
  • Access to gym on-site
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From$82 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Okawville : 812 North Henhouse Rd. 812 North Henhouse Rd., Okawville, IL 62271 Call ~32.28 miles south of Greenville
  • Cheap Rural property
  • Check-in time: 2pm
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From$76 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Okawville 812 North Hen House Rd., Okawville, IL 62271 Call ~32.28 miles south of Greenville
  • Cheap hotel
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From$72 total
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham O'fallon 1100 Eastgate Dr., Ofallon, IL 62269 Call ~33.41 miles southwest of Greenville
  • Economy Suburban hotel
  • Free breakfast
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From$48 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn Edwardsville - St. Louis 3080 South State Rte 157, Edwardsville, IL 62025 Call ~33.44 miles west of Greenville
  • Cheap Highway hotel
  • Gym / Fitness Center Available
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From$72 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Comfort Inn Edwardsville - Edwardsville 3080 Il 157, Edwardsville, IL 62025 Call ~33.44 miles west of Greenville
  • Three Star Highway hotel
  • Fitness center on property
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From$96 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites St. Louis Edwardsville 5723 Heritage Crossing Dr., Glen Carbon, IL 62034 Call ~33.74 miles west of Greenville
  • 3-star Suburban property
  • Comp. Breakfast
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From$118 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Best Western U. S. Inn 11640 State Route 127, Nashville, IL 62263 Call ~35.22 miles south of Greenville
  • 3 star Highway property
  • 48 rooms in property
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From$73 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Sleep Inn O Fallon Il - O'fallon 140 Venita Dr., O'fallon, IL 62269 Call ~35.35 miles southwest of Greenville
  • Midscale Suburban hotel
  • Free breakfast available
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From$96 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites O'fallon / Shiloh An Ihg Hotel 3396 Green Mount Crossing, Shiloh, IL 62269 Call ~35.48 miles southwest of Greenville
  • 3-star Highway property
  • Comp. Breakfast
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From$118 total
Very Good 4.0 /5 Review Score Call BookMore Details
Comfort Inn & Suites Ofallon St. Louis Area in O'fallon 116 Regency Park, O'fallon, IL 62269 Call ~35.51 miles southwest of Greenville
  • Low priced Suburban property
  • 19 suites in hotel
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From$72 total
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn O'fallon Il - O'fallon 430 Regency Park, O'fallon, IL 62269 Call ~35.57 miles southwest of Greenville
  • 3 star Suburban hotel
  • Hotel has 4 floors
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From$96 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis - O'fallon 136 Regency Park, O'fallon, IL 62269 Call ~35.59 miles southwest of Greenville
  • 2 star Suburban property
  • 2 floors in property
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From$72 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hilton Garden Inn St. Louis Shiloh / O'fallon Il - O'fallon 360 Regency Park, O'fallon, IL 62269 Call ~35.65 miles southwest of Greenville
  • 3-star Suburban property
  • 20 suites in hotel
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From$96 total
Average 3.0 /5 Read Reviews Call BookMore Details
Extended Stay America Select Suites - St. Louis - O' Fallon, IL 154 Regency Park, O'fallon, IL 62269 Call ~35.68 miles southwest of Greenville
  • Economy Highway hotel
  • 89 rooms in property
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From$46 total
Average 3.0 /5 Read Reviews Call BookMore Details
Welcome Suites in O'fallon 148 Regency Park, O'fallon, IL 62269 Call ~35.68 miles southwest of Greenville
  • Inexpensive Suburban hotel
  • 6 suites in hotel
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From$48 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details

Next: See My Greenville Hotels with Pricing

Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Pizza slices at Casey's was very good"
Score 5.0 / 5

Akia S., from 12-Jul-2026
"Quiet town"
Score 4.0 / 5

Quiet town and my Son plays Basketball for Greenville university.

Newton A., from 26-Feb-2026
"Great Diner!"
Score 4.0 / 5

Vicky's Cafe was awesome!! Very helpful and polite staff! Clean diner with great food!

Amy S., from 24-Aug-2025
"Dressed up Strip area."
Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025
"Quiet Area"
Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024
"Proximity to Carlyle"
Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024
"Greenville has some excellent museums!"
Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023
"Great Aquarium"
Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023
"College Campus"
Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023
"Loved It!"
Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022
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