Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels/Accommodations

Super 8 by Wyndham Greenville - Greenville

+1-888-389-4121

1700 State Route 127, Greenville, IL 62246 +1-888-389-4121

Cheap Rural hotel
Check in time: 12:00 PM

From$60

Average 3.0 /5 Read Reviews Call BookMore Details

SureStay by Best Western Greenville in Greenville

+1-888-675-2083

1731 South State Route 127, Greenville, IL 62246 +1-888-675-2083

Low priced Highway property
Free breakfast available

From$42

Average 3.0 /5 Review Score Call BookMore Details

Comfort Inn & Suites Greenville I-70

+1-800-716-8490

2265 South State Route 127, Greenville, IL 62246 Website +1-800-716-8490

Cheap Rural property
Hotel has 16 suites

From$53

Very good 4.0 /5 Hotel Reviews Call BookMore Details

Holiday Inn Express & Suites Vandalia Il

+1-800-805-5223

21 Mattes Ave., Vandalia, IL 62471 +1-800-805-5223 ~15.52 miles east of Greenville

Three Star Highway property
Has environment-friendly policy Read more

From$80

Average 3.0 /5 Guest Reviews Call BookMore Details

Ramada by Wyndham Vandalia : 2707 Veterans Ave.

+1-888-965-1860

2707 Veterans Ave., Vandalia, IL 62471 +1-888-965-1860 ~15.77 miles east of Greenville

Cheap property

From$60

Average 3.0 /5 Reviews Call BookMore Details

Americas Best Value Inn Vandalia

+1-888-788-5576

1500 North 6th St., Vandalia, IL 62471 +1-888-788-5576 ~17.45 miles east of Greenville

Low-priced Lake hotel
Check in time: 3.00

From$50

Average 3.0 /5 Latest Reviews Call BookMore Details

Quality Inn & Suites Vandalia near I-70 and Hwy 51

+1-888-897-9207

1920 North Kennedy Blvd., Vandalia, IL 62471 Website +1-888-897-9207 ~17.57 miles east of Greenville

2 star Highway property
Hotel has 8 suites

From$60

Very good 4.0 /5 Recent Reviews Call BookMore Details

Quality Inn & Suites Vandalia near I-70 and Hwy 51 in Vandalia

+1-888-311-4278

1920 Kennedy Blvd., Vandalia, IL 62471 +1-888-311-4278 ~17.59 miles east of Greenville

2-star Rural hotel
Hotel has an eco-friendly policy See policy

From$57

Very good 4.5 /5 Guest Reviews Call BookMore Details

Seasons Inn & Suites Highland in Highland

+1-888-469-4795

20 Central Blvd., Highland, IL 62249 +1-888-469-4795 ~17.74 miles southwest of Greenville

2 star hotel
Gym / Fitness Center Available

From$65

Average 3.0 /5 Review Score Call BookMore Details

Mariner's Village Resort & Inn - Carlyle

+1-888-734-9421

1 Resort Dr., Carlyle, IL 62231 +1-888-734-9421 ~18.34 miles south of Greenville

Economy Lake property
65 rooms in property

From$59

Very good 4.0 /5 Read Reviews Call BookMore Details

Centerstone Inn & Suites in Carlyle

+1-888-841-5292

1371 William Rd., Carlyle, IL 62231 +1-888-841-5292 ~18.46 miles south of Greenville

Inexpensive hotel
2 floors in property

From$60

Average 3.0 /5 Review Score Call BookMore Details

Super 8 by Wyndham Staunton

+1-888-455-5160

1527 Herman Rd., Staunton, IL 62088 +1-888-455-5160 ~21.09 miles west of Greenville

Economy hotel
2 floors in property

From$50

Very good 4.0 /5 Latest Reviews Call BookMore Details

Innkeeper Motel - Hamel

+1-888-965-8297

401 East State St., Hamel, IL 62046 +1-888-965-8297 ~23.07 miles west of Greenville

3-star Lake hotel
Check-in: 2:00 PM

From$80

Average 3.0 /5 Review Score Call BookMore Details

Americas Best Value Inn Litchfield

+1-888-906-6358

224 North Ohren Lane, Litchfield, IL 62056 +1-888-906-6358 ~24.10 miles northwest of Greenville

2 star hotel
Check in: 15:00

From$60

Poor 2.0 /5 Review Score Call BookMore Details

Motel 6 Litchfield, IL in Litchfield

+1-888-749-6785

211 Ohren Ln, Litchfield, IL 62056 +1-888-749-6785 ~24.16 miles northwest of Greenville

Inexpensive Highway hotel

From$60

Average 3.0 /5 Review Score Call BookMore Details

Baymont by Wyndham Litchfield : 1405 West Hudson Dr.

+1-888-878-9982

1405 West Hudson Dr., Litchfield, IL 62056 +1-888-878-9982 ~24.16 miles northwest of Greenville

Low priced Highway property
3 floors in hotel

From$60

Very good 4.0 /5 Guest Reviews Call BookMore Details

Quality Inn Litchfield Route 66

+1-888-389-4485

1010 East Columbian Blvd. North, Litchfield, IL 62056 Website +1-888-389-4485 ~24.37 miles northwest of Greenville

2 star Downtown hotel
Hotel has 15 suites

From$70

Very good 4.5 /5 Hotel Reviews Call BookMore Details

Hampton Inn Litchfield in Litchfield

+1-888-389-4121

11 Thunderbird Cir, Litchfield, IL 62056 +1-888-389-4121 ~24.48 miles northwest of Greenville

Affordable Highway property
Fitness / Gym is on-site

From$80

Average 3.0 /5 Reviews Call BookMore Details

Holiday Inn Express & Suites Litchfield West by IHG : 4 Thunderbird Circle

+1-888-675-2083

4 Thunderbird Circle, Litchfield, IL 62056 +1-888-675-2083 ~24.49 miles northwest of Greenville

Mid-scale Rural property
22 suites in property

From$79

Very good 4.0 /5 Reviews Call BookMore Details

Best Western Plus Centralia Hotel & Suites in Centralia

+1-800-716-8490

8145 Jolliff Bridge Rd., Centralia, IL 62801 +1-800-716-8490 ~28.09 miles southeast of Greenville

3-star hotel
3 conference rooms in property

From$78

Very good 4.0 /5 Read Reviews Call BookMore Details

Americas Best Value Inn

+1-800-805-5223

200 East Noleman, Centralia, IL 62801 +1-800-805-5223 ~29.09 miles southeast of Greenville

2 star property
57 rooms in property

From$60

Very good 4.0 /5 Hotel Reviews Call BookMore Details

Motel 6 Troy Il : 909 Edwardsville Rd.

+1-888-965-1860

909 Edwardsville Rd., Troy, IL 62294 +1-888-965-1860 ~29.31 miles west of Greenville

Cheap hotel
48 rooms in property

From$50

Average 3.0 /5 Read Reviews Call BookMore Details

Quality Inn & Suites Salem near I-57 - Salem

+1-888-788-5576

1800 West Main St., Salem, IL 62881 Website +1-888-788-5576 ~29.38 miles southeast of Greenville

Cheap Rural property
3 floors in hotel

From$69

Very good 4.0 /5 Hotel Reviews Call BookMore Details

Best Western Troy Hotel in Troy

+1-888-897-9207

2020 Formosa Rd., Troy, IL 62294 +1-888-897-9207 ~29.44 miles west of Greenville

Three Star Rural hotel
Fitness / Gym is on-site

From$60

Average 3.5 /5 Hotel Reviews Call BookMore Details

Holiday Inn Express Troy by IHG in Troy

+1-888-311-4278

2011 Formosa Rd., Troy, IL 62294 +1-888-311-4278 ~29.51 miles west of Greenville

3 star Highway property
18 suites in hotel

From$84

Very good 4.5 /5 Read Reviews Call BookMore Details

Red Roof Inn St Louis - Troy, IL

+1-888-469-4795

2030 Formosa Rd., Troy, IL 62294 +1-888-469-4795 ~29.55 miles west of Greenville

Low-priced hotel
Free breakfast available

From$53

Very good 4.0 /5 Reviews Call BookMore Details

Days Inn by Wyndham Salem, Illinois in Salem

+1-888-734-9421

1812 West Main St., Salem, IL 62881 +1-888-734-9421 ~29.55 miles southeast of Greenville

2 star hotel
Hotel has 2 floors

From$47

Very good 4.0 /5 Guest Reviews Call BookMore Details

Super 8 by Wyndham Troy IL/St. Louis Area - Troy

+1-888-841-5292

910 Edwardsville Rd., Troy, IL 62294 +1-888-841-5292 ~29.60 miles west of Greenville

Two star Highway property
Hotel has 61 rooms

From$63

Average 3.0 /5 Review Score Call BookMore Details

Super 8 by Wyndham Salem - Salem

+1-888-455-5160

118 Woods Ln, Salem, IL 62881 +1-888-455-5160 ~29.63 miles southeast of Greenville

Economy Highway property
Check-in time: 3:00pm

From$60

Average 3.0 /5 Hotel Reviews Call BookMore Details

Magnuson Grand Hotel And Conference Center - Raymond

+1-888-965-8297

19067 West Frontage Rd., Raymond, IL 62560 +1-888-965-8297 ~29.70 miles northwest of Greenville

Midscale Rural property
8 meeting rooms in hotel

From$49

Very good 4.0 /5 Reviews Call BookMore Details

Holiday Inn Express & Suites Salem by Ihg : 102 Holiday Lane

+1-888-906-6358

102 Holiday Lane, Salem, IL 62881 +1-888-906-6358 ~29.89 miles southeast of Greenville

Midscale Highway property
Fitness center on property

From$87

Excellent 5.0 /5 Hotel Reviews Call BookMore Details

Holiday Inn Express & Suites Edwardsville by IHG

+1-888-749-6785

1000 Plummer Dr., Edwardsville, IL 62025 +1-888-749-6785 ~31.59 miles west of Greenville

Mid-scale Suburban property
Hotel has 18 suites

From$94

Very good 4.0 /5 Read Reviews Call BookMore Details

Country Hearth Inn & Suites Edwardsville St. Louis : 1013 Plummer Dr.

+1-888-878-9982

1013 Plummer Dr., Edwardsville, IL 62025 +1-888-878-9982 ~31.66 miles west of Greenville

Affordable Rural hotel
Check-in: 15:00

From$67

Very good 4.0 /5 Reviews Call BookMore Details

TownePlace Suites by Marriott St. Louis Edwardsville, IL : 6101 Center Grove Rd.

+1-888-389-4485

6101 Center Grove Rd., Edwardsville, IL 62025 +1-888-389-4485 ~31.67 miles west of Greenville

Three Star Suburban property
5 floors in property

From$90

Very good 4.0 /5 Review Score Call BookMore Details

Best Western Plus MidAmerica Hotel in Mascoutah

+1-888-389-4121

9730 Hayden Dr., Mascoutah, IL 62258 +1-888-389-4121 ~32.05 miles southwest of Greenville

3-star Suburban hotel
3 floors in hotel

From$69

Very good 4.0 /5 Latest Reviews Call BookMore Details

Super 8 by Wyndham Okawville

+1-888-675-2083

812 North Henhouse Rd., Okawville, IL 62271 +1-888-675-2083 ~32.28 miles south of Greenville

Inexpensive Rural property
2 floors in property

From$64

Average 3.0 /5 Read Reviews Call BookMore Details

Super 8 by Wyndham Okawville - Okawville

+1-800-716-8490

812 North Hen House Rd., Okawville, IL 62271 +1-800-716-8490 ~32.28 miles south of Greenville

Economical hotel

From$60

Average 3.0 /5 Latest Reviews Call BookMore Details

Super 8 by Wyndham O'fallon : 1100 Eastgate Dr.

+1-800-805-5223

1100 Eastgate Dr., Ofallon, IL 62269 +1-800-805-5223 ~33.41 miles southwest of Greenville

Two-star Suburban hotel
Hotel has 8 suites

From$40

Average 3.0 /5 Review Score Call BookMore Details

Comfort Inn Edwardsville - St. Louis

+1-888-965-1860

3080 South State Rte 157, Edwardsville, IL 62025 Website +1-888-965-1860 ~33.44 miles west of Greenville

Economical Highway hotel
4 floors in property

From$60

Average 3.0 /5 Reviews Call BookMore Details

Hampton Inn & Suites St. Louis Edwardsville

+1-888-788-5576

5723 Heritage Crossing Dr., Glen Carbon, IL 62034 +1-888-788-5576 ~33.74 miles west of Greenville

Midscale Suburban property
Comp. Breakfast

From$99

Very good 4.0 /5 Read Reviews Call BookMore Details

Best Western U. S. Inn - Nashville

+1-888-897-9207

11640 State Route 127, Nashville, IL 62263 +1-888-897-9207 ~35.22 miles south of Greenville

Affordable Highway property
Complimentary breakfast is offered

From$64

Very good 4.0 /5 Recent Reviews Call BookMore Details

Sleep Inn O Fallon Il in O'fallon

+1-888-311-4278

140 Venita Dr., O'fallon, IL 62269 +1-888-311-4278 ~35.35 miles southwest of Greenville

Mid-scale Suburban hotel
Hotel has 3 floors

From$80

Average 3.0 /5 Latest Reviews Call BookMore Details

Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG

+1-888-469-4795

3396 Green Mt. Crossing Dr., Shiloh, IL 62269 +1-888-469-4795 ~35.49 miles southwest of Greenville

Midscale Highway hotel
Check-in time: 3:00

From$80

Average 3.0 /5 Hotel Reviews Call BookMore Details

Comfort Inn & Suites Ofallon St. Louis Area

+1-888-734-9421

116 Regency Park, O'fallon, IL 62269 +1-888-734-9421 ~35.51 miles southwest of Greenville

Inexpensive Suburban hotel
Complimentary breakfast is offered

From$60

Average 3.0 /5 Review Score Call BookMore Details

Hampton Inn O'fallon Il in O'fallon

+1-888-841-5292

430 Regency Park, O'fallon, IL 62269 +1-888-841-5292 ~35.57 miles southwest of Greenville

Midscale Suburban hotel
4 floors in hotel

From$80

Very good 4.0 /5 Recent Reviews Call BookMore Details

La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis : 136 Regency Park

+1-888-455-5160

136 Regency Park, O'fallon, IL 62269 +1-888-455-5160 ~35.59 miles southwest of Greenville

Cheap Suburban property
Check in time: 3:00 PM

From$60

Average 3.0 /5 Review Score Call BookMore Details

Hilton Garden Inn St. Louis Shiloh / O'fallon Il in O'fallon

+1-888-965-8297

360 Regency Park, O'fallon, IL 62269 +1-888-965-8297 ~35.65 miles southwest of Greenville

3-star Suburban hotel
128 rooms in property

From$80

Average 3.0 /5 Reviews Call BookMore Details

Extended Stay America Select Suites - St. Louis - O' Fallon, IL

+1-888-906-6358

154 Regency Park, O'fallon, IL 62269 +1-888-906-6358 ~35.68 miles southwest of Greenville

Low priced Highway property
Check in time: 3:00 PM

From$39

Average 3.0 /5 Guest Reviews Call BookMore Details

Welcome Suites : 148 Regency Park

+1-888-749-6785

148 Regency Park, O'fallon, IL 62269 +1-888-749-6785 ~35.68 miles southwest of Greenville

Economical Suburban hotel
89 rooms in hotel

From$40

Very good 4.0 /5 Review Score Call BookMore Details

Towneplace Place Suites by Marriott St. Louis O Fallon Illinois in Ofallon

+1-888-878-9982

445 Regency Park Dr., Ofallon, IL 62269 +1-888-878-9982 ~35.68 miles southwest of Greenville

Three Star property
Hotel has 89 suites

From$90

Very good 4.0 /5 Review Score Call BookMore Details

Next: See My Greenville Hotels with Pricing

Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Great Diner!"

Score 4.0 / 5

Vicky's Cafe was awesome!! Very helpful and polite staff! Clean diner with great food!

Amy S., from 24-Aug-2025

"Dressed up Strip area."

Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025

"Quiet Area"

Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024

"Proximity to Carlyle"

Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024

"Greenville has some excellent museums!"

Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023

"Great Aquarium"

Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023

"College Campus"

Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023

"Loved It!"

Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022

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