Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels & Accommodations

Super 8 by Wyndham Greenville in Greenville
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1700 State Route 127, Greenville, IL 62246 +1-888-389-4121
  • Cheap Rural property
  • Complimentary breakfast is offered
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From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
SureStay by Best Western Greenville
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1731 South State Route 127, Greenville, IL 62246 +1-888-675-2083
  • 2 star Highway hotel
  • 77 rooms in property
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From$42
Average 3.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites Greenville I-70 - Greenville
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
2265 South State Route 127, Greenville, IL 62246 Website +1-800-716-8490
  • Low Cost Rural property
  • Check-in time: 3:00 PM
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From$53
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Vandalia Il : 21 Mattes Ave.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
21 Mattes Ave., Vandalia, IL 62471 +1-800-805-5223 ~15.52 miles east of Greenville
  • Midscale Highway hotel
  • Hotel has a green policy See policy
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Ramada by Wyndham Vandalia
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
2707 Veterans Ave., Vandalia, IL 62471 +1-888-965-1860 ~15.77 miles east of Greenville
  • Low-priced hotel
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From$60
Average 3.0 /5 Reviews Call BookMore Details
Americas Best Value Inn Vandalia in Vandalia
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1500 North 6th St., Vandalia, IL 62471 +1-888-788-5576 ~17.45 miles east of Greenville
  • Inexpensive Lake property
  • Check in time: 3.00
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From$50
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 : 1920 North Kennedy Blvd.
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1920 North Kennedy Blvd., Vandalia, IL 62471 Website +1-888-897-9207 ~17.57 miles east of Greenville
  • Cheap Highway hotel
  • Hotel has an eco-friendly policy Learn more
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From$60
Very Good 4.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 in Vandalia
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1920 Kennedy Blvd., Vandalia, IL 62471 +1-888-311-4278 ~17.59 miles east of Greenville
  • Low Cost Rural hotel
  • Hotel has 85 rooms
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From$57
Very Good 4.5 /5 Read Reviews Call BookMore Details
Seasons Inn & Suites in Highland
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
20 Central Blvd., Highland, IL 62249 +1-888-469-4795 ~17.74 miles southwest of Greenville
  • Low Cost property
  • Check-in time: 3:00 PM
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From$65
Average 3.0 /5 Hotel Reviews Call BookMore Details
Mariner's Village Resort & Inn - Carlyle
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1 Resort Dr., Carlyle, IL 62231 +1-888-734-9421 ~18.34 miles south of Greenville
  • Low-priced Lake property
  • Comp. Breakfast
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From$59
Very Good 4.0 /5 Review Score Call BookMore Details
Centerstone Inn & Suites
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1371 William Rd., Carlyle, IL 62231 +1-888-841-5292 ~18.46 miles south of Greenville
  • Low Cost hotel
  • 2 floors in property
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From$60
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Staunton - Staunton
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1527 Herman Rd., Staunton, IL 62088 +1-888-455-5160 ~21.09 miles west of Greenville
  • Cheap property
  • 3 suites in property
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From$50
Very Good 4.0 /5 Read Reviews Call BookMore Details
Innkeeper Motel - Hamel
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
401 East State St., Hamel, IL 62046 +1-888-965-8297 ~23.07 miles west of Greenville
  • Midscale Lake property
  • Check-in time: 2:00 PM
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From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Americas Best Value Inn Litchfield
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
224 North Ohren Lane, Litchfield, IL 62056 +1-888-906-6358 ~24.10 miles northwest of Greenville
  • Two star hotel
  • 65 sleeping rooms in hotel
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From$60
Poor 2.0 /5 Reviews Call BookMore Details
Motel 6 Litchfield, IL
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
211 Ohren Ln, Litchfield, IL 62056 +1-888-749-6785 ~24.16 miles northwest of Greenville
  • 2 star Highway hotel
  • Check-in: 11:00 AM
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From$60
Average 3.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Litchfield
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1405 West Hudson Dr., Litchfield, IL 62056 +1-888-878-9982 ~24.16 miles northwest of Greenville
  • 2 star Highway hotel
  • Hotel has an eco-friendly policy Learn more
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From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Inn Litchfield Route 66 - Litchfield
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1010 East Columbian Blvd. North, Litchfield, IL 62056 Website +1-888-389-4485 ~24.37 miles northwest of Greenville
  • 2 star Downtown property
  • 3 floors in hotel
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From$70
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Hampton Inn Litchfield : 11 Thunderbird Cir
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
11 Thunderbird Cir, Litchfield, IL 62056 +1-888-389-4121 ~24.48 miles northwest of Greenville
  • Three Star Highway hotel
  • 9 suites in hotel
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Litchfield West by IHG
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
4 Thunderbird Circle, Litchfield, IL 62056 +1-888-675-2083 ~24.49 miles northwest of Greenville
  • Midscale Rural hotel
  • Fitness center on property
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From$79
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Best Western Plus Centralia Hotel & Suites
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
8145 Jolliff Bridge Rd., Centralia, IL 62801 +1-800-716-8490 ~28.09 miles southeast of Greenville
  • 3 star hotel
  • 17 suites in hotel
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From$78
Very Good 4.0 /5 Reviews Call BookMore Details
Americas Best Value Inn : 200 East Noleman
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
200 East Noleman, Centralia, IL 62801 +1-800-805-5223 ~29.09 miles southeast of Greenville
  • Low-priced property
  • Check in: 2:00 PM
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From$60
Very Good 4.0 /5 Reviews Call BookMore Details
Motel 6 Troy Il
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
909 Edwardsville Rd., Troy, IL 62294 +1-888-965-1860 ~29.31 miles west of Greenville
  • Two-star hotel
  • 48 rooms in property
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From$50
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Salem near I-57 in Salem
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1800 West Main St., Salem, IL 62881 Website +1-888-788-5576 ~29.38 miles southeast of Greenville
  • Two-star Rural hotel
  • 3 floors in property
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From$69
Very Good 4.0 /5 Read Reviews Call BookMore Details
Best Western Troy Hotel
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2020 Formosa Rd., Troy, IL 62294 +1-888-897-9207 ~29.44 miles west of Greenville
  • Affordable Rural hotel
  • Hotel has 65 rooms
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From$60
Average 3.5 /5 Read Reviews Call BookMore Details
Holiday Inn Express Troy by IHG : 2011 Formosa Rd.
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2011 Formosa Rd., Troy, IL 62294 +1-888-311-4278 ~29.51 miles west of Greenville
  • 3 star Highway property
  • 4 floors in property
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From$84
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Red Roof Inn St Louis - Troy, IL
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2030 Formosa Rd., Troy, IL 62294 +1-888-469-4795 ~29.55 miles west of Greenville
  • Low Cost hotel
  • 72 sleeping rooms in hotel
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From$53
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Salem, Illinois : 1812 West Main St.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1812 West Main St., Salem, IL 62881 +1-888-734-9421 ~29.55 miles southeast of Greenville
  • Inexpensive hotel
  • Fitness center on property
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From$47
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Troy IL/St. Louis Area - Troy
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
910 Edwardsville Rd., Troy, IL 62294 +1-888-841-5292 ~29.60 miles west of Greenville
  • Low priced Highway hotel
  • Free comp. breakfast
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From$63
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Salem
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
118 Woods Ln, Salem, IL 62881 +1-888-455-5160 ~29.63 miles southeast of Greenville
  • Cheap Highway hotel
  • Hotel has a green policy Learn more
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From$60
Average 3.0 /5 Review Score Call BookMore Details
Magnuson Grand Hotel And Conference Center
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
19067 West Frontage Rd., Raymond, IL 62560 +1-888-965-8297 ~29.70 miles northwest of Greenville
  • 3 star Rural hotel
  • 8 meeting rooms in hotel
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From$49
Very Good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Salem by Ihg
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
102 Holiday Lane, Salem, IL 62881 +1-888-906-6358 ~29.89 miles southeast of Greenville
  • Mid-scale Highway property
  • 86 rooms in property
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From$87
Excellent 5.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Edwardsville by IHG - Edwardsville
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1000 Plummer Dr., Edwardsville, IL 62025 +1-888-749-6785 ~31.59 miles west of Greenville
  • Mid-scale Suburban property
  • Fitness center on property
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From$94
Very Good 4.0 /5 Read Reviews Call BookMore Details
Country Hearth Inn & Suites Edwardsville St. Louis : 1013 Plummer Dr.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1013 Plummer Dr., Edwardsville, IL 62025 +1-888-878-9982 ~31.66 miles west of Greenville
  • Affordable Rural property
  • Access to gym on-site
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From$67
Very Good 4.0 /5 Guest Reviews Call BookMore Details
TownePlace Suites by Marriott St. Louis Edwardsville, IL in Edwardsville
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
6101 Center Grove Rd., Edwardsville, IL 62025 +1-888-389-4485 ~31.67 miles west of Greenville
  • 3 star Suburban property
  • 91 rooms in property
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From$90
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Best Western Plus MidAmerica Hotel in Mascoutah
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
9730 Hayden Dr., Mascoutah, IL 62258 +1-888-389-4121 ~32.05 miles southwest of Greenville
  • Three Star Suburban property
  • Gym / Fitness Center Available
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From$69
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Okawville - Okawville
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
812 North Henhouse Rd., Okawville, IL 62271 +1-888-675-2083 ~32.28 miles south of Greenville
  • Low-priced Rural property
  • 2 floors in property
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From$64
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Okawville - Okawville
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
812 North Hen House Rd., Okawville, IL 62271 +1-800-716-8490 ~32.28 miles south of Greenville
  • Low priced property
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From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham O'fallon : 1100 Eastgate Dr.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1100 Eastgate Dr., Ofallon, IL 62269 +1-800-805-5223 ~33.41 miles southwest of Greenville
  • Low priced Suburban property
  • Fitness + Health Center
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From$40
Average 3.0 /5 Reviews Call BookMore Details
Comfort Inn Edwardsville - St. Louis
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3080 South State Rte 157, Edwardsville, IL 62025 Website +1-888-965-1860 ~33.44 miles west of Greenville
  • Cheap Highway property
  • Free comp. breakfast
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From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites St. Louis Edwardsville
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
5723 Heritage Crossing Dr., Glen Carbon, IL 62034 +1-888-788-5576 ~33.74 miles west of Greenville
  • Mid-scale Suburban property
  • Hotel has 72 rooms
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From$99
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Best Western U. S. Inn
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
11640 State Route 127, Nashville, IL 62263 +1-888-897-9207 ~35.22 miles south of Greenville
  • Midscale Highway hotel
  • Complimentary breakfast is offered
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From$64
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Sleep Inn O Fallon Il - O'fallon
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
140 Venita Dr., O'fallon, IL 62269 +1-888-311-4278 ~35.35 miles southwest of Greenville
  • 3 star Suburban property
  • Fitness + Health Center
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
3396 Green Mt. Crossing Dr., Shiloh, IL 62269 +1-888-469-4795 ~35.49 miles southwest of Greenville
  • Mid-scale Highway property
  • 80 rooms in hotel
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From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn & Suites Ofallon St. Louis Area
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
116 Regency Park, O'fallon, IL 62269 +1-888-734-9421 ~35.51 miles southwest of Greenville
  • 2-star Suburban hotel
  • Free comp. breakfast
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From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn O'fallon Il - O'fallon
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
430 Regency Park, O'fallon, IL 62269 +1-888-841-5292 ~35.57 miles southwest of Greenville
  • Midscale Suburban property
  • Hotel has 4 floors
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From$80
Very Good 4.0 /5 Read Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis - O'fallon
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
136 Regency Park, O'fallon, IL 62269 +1-888-455-5160 ~35.59 miles southwest of Greenville
  • Low-priced Suburban property
  • 2 floors in property
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From$60
Average 3.0 /5 Review Score Call BookMore Details
Hilton Garden Inn St. Louis Shiloh / O'fallon Il : 360 Regency Park
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
360 Regency Park, O'fallon, IL 62269 +1-888-965-8297 ~35.65 miles southwest of Greenville
  • Affordable Suburban hotel
  • 3 conference rooms in property
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From$80
Average 3.0 /5 Review Score Call BookMore Details
Extended Stay America Select Suites - St. Louis - O' Fallon, IL
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
154 Regency Park, O'fallon, IL 62269 +1-888-906-6358 ~35.68 miles southwest of Greenville
  • 2-star Highway hotel
  • Check-in time: 3:00 PM
More Photos
From$39
Average 3.0 /5 Reviews Call BookMore Details
Drury Inn St. Louis Collinsville
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
602 North Bluff Rd., Collinsville, IL 62234 +1-888-749-6785 ~35.68 miles west of Greenville
  • 3 star Suburban hotel
  • Hotel has a green policy Learn more
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From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Welcome Suites - O'fallon
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
148 Regency Park, O'fallon, IL 62269 +1-888-878-9982 ~35.68 miles southwest of Greenville
  • Low priced Suburban property
  • 89 rooms in hotel
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From$40
Very Good 4.0 /5 Guest Reviews Call BookMore Details

Next: See My Greenville Hotels with Pricing

Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Great Diner!"
Score 4.0 / 5

Vicky's Cafe was awesome!! Very helpful and polite staff! Clean diner with great food!

Amy S., from 24-Aug-2025
"Dressed up Strip area."
Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025
"Quiet Area"
Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024
"Proximity to Carlyle"
Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024
"Greenville has some excellent museums!"
Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023
"Great Aquarium"
Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023
"College Campus"
Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023
"Loved It!"
Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022
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