Hartsville South Carolina Hotels & Motels

Find accommodations in Hartsville with the hotel list provided below. Find cheap and/or discounted hotel rates in or near Hartsville, SC for your upcoming personal or group travel. We show the best Hartsville, South Carolina motel and hotel rooms. Browse the Hartsville area hotels to find the perfect lodging! Please use the provided map of the Hartsville hotels. Planning a group? Lock in Hartsville Group Hotel Rates

The Hartsville center is about the area of Coker College and 10 miles west of Darlington Raceway NASCAR.

Hartsville Hotels/Motels & Accommodations

The Mantissa Executive Suites & Spa
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
130 East Carolina Ave., Hartsville, SC 29550 +1-888-389-4121
  • Midscale Downtown property
  • Gym / Fitness Center Available
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From$160
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Hartsville - Hartsville
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
203 East Carolina Ave., Hartsville, SC 29550 +1-888-675-2083
  • 3-star Downtown hotel
  • 4 floors in property
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From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn by Marriott Hartsville in Hartsville
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
200 South 4th St., Hartsville, SC 29550 +1-800-716-8490
  • Cheap Rural property
  • Free complimentary breakfast
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From$79
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Inn in Hartsville
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
903 South 5th St., Hartsville, SC 29550 +1-800-805-5223
  • 2-star Downtown property
  • Check in time: 3:00
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From$75
Very Good 4.0 /5 Reviews Call BookMore Details
Landmark Inn : 1301 South 4th St.
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1301 South 4th St., Hartsville, SC 29550 +1-888-965-1860
  • Midscale Rural property
  • 2 floors in property
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From$53
Average 3.0 /5 Reviews Call BookMore Details
Americas Best Value Inn Bishopville
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
27 Charlenes Lane, Bishopville, SC 29010 +1-888-788-5576 ~15.33 miles southwest of Hartsville
  • 2-star Highway property
  • Check-in: 11:00AM
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From$60
Average 3.5 /5 Read Reviews Call BookMore Details
Red Roof Inn Bishopville
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1135 Sumter Highway, Bishopville, SC 29010 +1-888-897-9207 ~15.54 miles southwest of Hartsville
  • Low priced property
  • 48 rooms in hotel
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From$39
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Florence : 1912 Enterprise Dr.
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1912 Enterprise Dr., Florence, SC 29501 +1-888-311-4278 ~18.05 miles southeast of Hartsville
  • Two star Highway hotel
  • Hotel has 3 floors
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From$39
Poor 2.5 /5 Read Reviews Call BookMore Details
Tru by Hilton Florence I-95 : 2140 West Lucas St.
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2140 West Lucas St., Florence, SC 29501 +1-888-469-4795 ~18.11 miles southeast of Hartsville
  • 3-star hotel
  • Hotel has 98 rooms
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From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Sleep Inn Florence : 1833 Florence Park Dr.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1833 Florence Park Dr., Florence, SC 29501 +1-888-734-9421 ~18.13 miles southeast of Hartsville
  • Economy Highway property
  • Check in time: 3:00pm
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From$59
Average 3.0 /5 Reviews Call BookMore Details
Comfort Suites Florence I-95 : 2120 West Lucas St.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2120 West Lucas St., Florence, SC 29501 +1-888-841-5292 ~18.16 miles southeast of Hartsville
  • Three Star Highway hotel
  • Hotel has a green policy See policy
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From$80
Very Good 4.0 /5 Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Florence
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
2123 West Lucas St., Florence, SC 29501 +1-888-455-5160 ~18.28 miles southeast of Hartsville
  • Affordable Highway hotel
  • Free breakfast available
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From$82
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Florence North
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1735 Stokes Rd., Florence, SC 29501 +1-888-965-8297 ~18.28 miles southeast of Hartsville
  • Low Cost Highway property
  • Free breakfast available
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From$104
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Florence/I-95 North : 2111 West Lucas
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
2111 West Lucas, Florence, SC 29501 +1-888-906-6358 ~18.29 miles southeast of Hartsville
  • Low-priced Highway hotel
  • Complimentary breakfast is offered
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From$50
Average 3.5 /5 Guest Reviews Call BookMore Details
Howard Johnson by Wyndham Florence
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
2038 West Lucas St., Florence, SC 29501 +1-888-749-6785 ~18.33 miles southeast of Hartsville
  • Economy Highway hotel
  • Complimentary breakfast is offered
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From$60
Poor 2.0 /5 Guest Reviews Call BookMore Details
Homewood Suites by Hilton Florence in Florence
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
3450 West Radio Dr., Florence, SC 29501 +1-888-878-9982 ~18.36 miles southeast of Hartsville
  • Midscale Convention Center property
  • Complimentary breakfast is offered
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From$80
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Civic Center
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
150 Dunbarton Dr., Florence, SC 29501 +1-888-389-4485 ~18.36 miles southeast of Hartsville
  • Low Cost Highway hotel
  • 80 sleeping rooms in hotel
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From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Park Inn by Radisson in Florence
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1729 Mandeville Rd., Florence, SC 29501 +1-888-389-4121 ~18.38 miles southeast of Hartsville
  • Economy Highway hotel
  • 60 rooms in hotel
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From$75
Average 3.0 /5 Hotel Reviews Call BookMore Details
Park Inn by Radisson Florence Sc in Florence
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1729 Mandeville Rd., Florence, SC 27407 +1-888-675-2083 ~18.38 miles southeast of Hartsville
  • Mid-scale property
  • 60 rooms in property
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From$90
Very Good 4.0 /5 Review Score Call BookMore Details
Country Inn & Suites by Radisson Florence Sc : 1739 Mandeville Rd.
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1739 Mandeville Rd., Florence, SC 29501 +1-800-716-8490 ~18.39 miles southeast of Hartsville
  • 3 star Highway hotel
  • Free comp. breakfast
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From$79
Very Good 4.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Florence Near Civic Center in Florence
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
140 Dunbarton Dr., Florence, SC 29501 +1-800-805-5223 ~18.40 miles southeast of Hartsville
  • Two-star Convention Center hotel
  • Access to gym on-site
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From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Suburban Studios in Florence
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1914 West Lucas St., Florence, SC 29501 +1-888-965-1860 ~18.44 miles southeast of Hartsville
  • Low Cost Highway hotel
  • 24 suites in property
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From$42
Poor 2.0 /5 Reviews Call BookMore Details
Staybridge Suites - Florence
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
150 Westpark Dr., Florence, SC 29501 +1-888-788-5576 ~18.47 miles southeast of Hartsville
  • 3-star Convention Center hotel
  • 112 rooms in hotel
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From$133
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Motel 6 Florence, SC
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2004 West Lucas St., Florence, SC 29501 +1-888-897-9207 ~18.48 miles southeast of Hartsville
  • Low-priced Downtown property
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From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr, an I
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
3440 West Radio Dr., Florence, SC 29501 +1-888-311-4278 ~18.54 miles southeast of Hartsville
  • Midscale Convention Center hotel
  • Hotel has 23 suites
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From$95
Very Good 4.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Florence Center in Florence
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
3000 West Radio Dr., Florence, SC 29501 +1-888-469-4795 ~18.54 miles southeast of Hartsville
  • 3 star Convention Center hotel
  • Hotel has 82 rooms
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From$109
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hilton Garden Inn
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
2671 Hospitality Blvd., Florence, SC 29501 +1-888-734-9421 ~18.68 miles southeast of Hartsville
  • Affordable Highway hotel
  • Check in time: 3:00 pm
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From$109
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Springhill Suites by Marriott Florence
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2670 Hospitality Blvd., Florence, SC 29501 +1-888-841-5292 ~18.69 miles southeast of Hartsville
  • Mid-scale Convention Center property
  • Gym / Fitness Center Available
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From$89
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Knights Inn Florence
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1834 West Lucas St., Florence, SC 29501 +1-888-455-5160 ~18.70 miles southeast of Hartsville
  • Low-priced property
  • 109 rooms in property
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From$50
Poor 2.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Florence
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2680 Hospitality Blvd., Florence, SC 29501 +1-888-965-8297 ~18.70 miles southeast of Hartsville
  • Midscale Convention Center property
  • 90 sleeping rooms in hotel
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From$99
Average 3.0 /5 Hotel Reviews Call BookMore Details
Home2 Suites by Hilton Florence, SC
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
900 Woody Jones Blvd., Florence, SC 29501 +1-888-906-6358 ~18.74 miles southeast of Hartsville
  • Mid-scale Convention Center hotel
  • Hotel has 5 suites
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From$89
Very Good 4.0 /5 Review Score Call BookMore Details
Clarion Inn & Suites : 1819 Building a West Lucas St.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1819 Building a West Lucas St., Florence, SC 29501 +1-888-749-6785 ~18.74 miles southeast of Hartsville
  • Mid-scale Highway property
  • Check-in time: 3:00
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From$80
Average 3.0 /5 Review Score Call BookMore Details
Mainstay Suites Florence Sc
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1819 West Lucas St. Building B, Florence, SC 29501 +1-888-878-9982 ~18.74 miles southeast of Hartsville
  • Two-star Highway property
  • Hotel has 15 suites
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Florence
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1832 1 / 2 Lucas St., Florence, SC 29501 +1-888-389-4485 ~18.75 miles southeast of Hartsville
  • Economical Highway hotel
  • Check in: 11:00 AM
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From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Residence Inn Marriott Florence : 2660 Hospitality Blvd.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
2660 Hospitality Blvd., Florence, SC 29501 +1-888-389-4121 ~18.77 miles southeast of Hartsville
  • Three Star Suburban hotel
  • Hotel has 4 floors
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From$94
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Baymont Inn & Suites Florence by Wyndham : 1826 West Lucas St.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1826 West Lucas St., Florence, SC 29501 +1-888-675-2083 ~18.80 miles southeast of Hartsville
  • Two-star Highway property
  • Check-in: 3:00pm
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From$55
Poor 2.0 /5 Recent Reviews Call BookMore Details
Fairview Inn Florence in Florence
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1811 West Lucas St., Florence, SC 29501 +1-800-716-8490 ~18.85 miles southeast of Hartsville
  • Low Cost Highway hotel
  • 60 rooms in hotel
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From$40
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Best Western Inn in Florence
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1808 West Lucas St., Florence, SC 29501 +1-800-805-5223 ~18.88 miles southeast of Hartsville
  • Three Star Downtown property
  • 74 rooms in hotel
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From$89
Average 3.0 /5 Hotel Reviews Call BookMore Details
Towneplace Suites by Marriott Florence - Florence
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
2650 Hospitality Blvd., Florence, SC 29501 +1-888-965-1860 ~18.89 miles southeast of Hartsville
  • Mid-scale Suburban hotel
  • 4 floors in property
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From$94
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Red Roof Inn Florence - Civic Center
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2690 David Mcleod Blvd., Florence, SC 29501 +1-888-788-5576 ~18.93 miles southeast of Hartsville
  • Luxurious 5 Star Highway property
  • Shuttle from airport available
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From$61
Average 3.0 /5 Reviews Call BookMore Details
Travelodge by Wyndham Florence
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
3783a West Palmetto St., Florence, SC 29502 +1-888-897-9207 ~18.95 miles southeast of Hartsville
  • Low priced Highway hotel
  • Comp. Breakfast
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From$60
Not Good 1.0 /5 Guest Reviews Call BookMore Details
Travelodge by Wyndham Florence : 1084 Oregon Coast Highway
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1084 Oregon Coast Highway, Florence, OR 97439 +1-888-311-4278 ~18.95 miles southeast of Hartsville
  • Economical property
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From$99
Average 3.0 /5 Review Score Call BookMore Details
Comfort Inn & Suites Florence
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
527 Woody Jones Blvd., Sc 554, SC 29501 +1-888-469-4795 ~18.99 miles southeast of Hartsville
  • Midscale Suburban property
  • Check-in: 4:00 PM
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From$80
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Florence I-20
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
501 Woody Jones Blvd., Florence, SC 29501 +1-888-734-9421 ~19.02 miles southeast of Hartsville
  • Midscale Convention Center property
  • Hotel has 3 floors
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From$99
Average 3.0 /5 Hotel Reviews Call BookMore Details
Days Inn Florence
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
3783 West Palmetto St. I 95, Florence, SC 29501 +1-888-841-5292 ~19.04 miles southeast of Hartsville
  • Two-star Highway hotel
  • Check in time: 2pm
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From$39
Poor 2.5 /5 Hotel Reviews Call BookMore Details
Travelodge by Wyndham Florence
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3783a West Palmetto St., Florence, SC 29501 +1-888-455-5160 ~19.04 miles southeast of Hartsville
  • Cheap Highway property
  • 120 rooms in hotel
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From$58
Not Good 1.0 /5 Latest Reviews Call BookMore Details
Florence Express Inn
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
3024 Tv Rd., Florence, SC 29501 +1-888-965-8297 ~20.96 miles east of Hartsville
  • Economy Highway hotel
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From$60
Poor 2.5 /5 Reviews Call BookMore Details
Rodeway Inn & Suites
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
181 West Lucas St., Florence, SC 29501 +1-888-906-6358 ~20.99 miles southeast of Hartsville
  • Low Cost property
  • Comp. Breakfast
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hotel Florence Tapestry Collection by Hilton
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
126 West Evans St., Florence, SC 29501 +1-888-749-6785 ~21.37 miles southeast of Hartsville
  • 3-star Downtown property
  • Check-in: 4:00pm
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From$114
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hyatt Place Florence Downtown : 100 East Evans St.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
100 East Evans St., Florence, SC 29501 +1-888-878-9982 ~21.42 miles southeast of Hartsville
  • 4 star property
  • 101 sleeping rooms in hotel
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From$160
Very Good 4.0 /5 Guest Reviews Call BookMore Details

Next: See My Hartsville Hotels with Pricing

Recent traveler guest reviews of Hartsville, SC

Below are reviews of the city of Hartsville, SC from an actual visitor's perspective.

"Very Nice"
Score 5.0 / 5

Very nice!

Donald K., from 23-Mar-2024
"Proximity to Downtown & Coker University"
Score 5.0 / 5

Downtown area and Coker University.

Ernest S., from 13-Feb-2024
"Nice, quiet, clean."
Score 5.0 / 5

Nice, quiet, clean.

Lucinda W., from 29-Oct-2023
"Clean & Awesome Hotel"
Score 4.0 / 5

The hotel staff was awesome at the desk. It was very clean there. The places we visited were really nice. Shoney's was clean with great food and great help.

Portia R., from 29-Aug-2023
"Helpful Staff "
Score 5.0 / 5

Nearby rooftop bar. Front desk agent, WHITNEY, was very friendly, helpful and professional! THANKS!!

Eddie D., from 03-Aug-2022
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