Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels/Accommodations

Super 8 by Wyndham Greenville 1700 State Route 127, Greenville, IL 62246 Call
  • Low Cost Rural hotel
  • Check-in: 12:00 PM
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From£53 total
Average 3.0 /5 Latest Reviews Call BookMore Details
SureStay by Best Western Greenville : 1731 South State Route 127 1731 South State Route 127, Greenville, IL 62246 Call
  • Cheap Highway hotel
  • 77 rooms in property
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From£36 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn & Suites Greenville I-70 : 2265 South State Route 127 2265 South State Route 127, Greenville, IL 62246 Website Call
  • Economical Rural property
  • Fitness center on property
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From£47 total
Very good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Vandalia Il - Vandalia 21 Mattes Ave., Vandalia, IL 62471 Call ~15.52 miles east of Greenville
  • Affordable Highway property
  • Hotel has 70 rooms
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From£71 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Ramada by Wyndham Vandalia : 2707 Veterans Ave. 2707 Veterans Ave., Vandalia, IL 62471 Call ~15.77 miles east of Greenville
  • Two-star hotel
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From£53 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Americas Best Value Inn Vandalia 1500 North 6th St., Vandalia, IL 62471 Call ~17.45 miles east of Greenville
  • Cheap Lake property
  • Check in: 3.00
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From£44 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 1920 North Kennedy Blvd., Vandalia, IL 62471 Website Call ~17.57 miles east of Greenville
  • Two-star Highway property
  • Free complimentary breakfast
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From£53 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 - Vandalia 1920 Kennedy Blvd., Vandalia, IL 62471 Call ~17.59 miles east of Greenville
  • Cheap Rural hotel
  • Free comp. breakfast
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From£50 total
Very good 4.5 /5 Reviews Call BookMore Details
Seasons Inn & Suites Highland in Highland 20 Central Blvd., Highland, IL 62249 Call ~17.74 miles southwest of Greenville
  • Low-priced property
  • 3 floors in property
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From£57 total
Average 3.0 /5 Read Reviews Call BookMore Details
Mariner's Village Resort & Inn : 1 Resort Dr. 1 Resort Dr., Carlyle, IL 62231 Call ~18.34 miles south of Greenville
  • Low priced Lake hotel
  • Check in time: 15:00
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From£52 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
Centerstone Inn & Suites - Carlyle 1371 William Rd., Carlyle, IL 62231 Call ~18.46 miles south of Greenville
  • 2 star hotel
  • 41 sleeping rooms in hotel
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From£53 total
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Staunton 1527 Herman Rd., Staunton, IL 62088 Call ~21.09 miles west of Greenville
  • Inexpensive hotel
  • Free breakfast available
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From£44 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
Innkeeper Motel : 401 East State St. 401 East State St., Hamel, IL 62046 Call ~23.07 miles west of Greenville
  • 3-star Lake property
  • Hotel has 24 rooms
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From£71 total
Average 3.0 /5 Review Score Call BookMore Details
Americas Best Value Inn Litchfield in Litchfield 224 North Ohren Lane, Litchfield, IL 62056 Call ~24.10 miles northwest of Greenville
  • Low-priced property
  • Check-in time: 15:00
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From£53 total
Poor 2.0 /5 Guest Reviews Call BookMore Details
Motel 6 Litchfield, IL 211 Ohren Ln, Litchfield, IL 62056 Call ~24.16 miles northwest of Greenville
  • Low priced Highway property
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From£53 total
Average 3.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Litchfield : 1405 West Hudson Dr. 1405 West Hudson Dr., Litchfield, IL 62056 Call ~24.16 miles northwest of Greenville
  • Low-priced Highway property
  • 64 rooms in hotel
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From£53 total
Very good 4.0 /5 Latest Reviews Call BookMore Details
Quality Inn Litchfield Route 66 in Litchfield 1010 East Columbian Blvd. North, Litchfield, IL 62056 Website Call ~24.37 miles northwest of Greenville
  • Low priced Downtown property
  • Hotel has 3 floors
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From£62 total
Very good 4.5 /5 Reviews Call BookMore Details
Hampton Inn Litchfield : 11 Thunderbird Cir 11 Thunderbird Cir, Litchfield, IL 62056 Call ~24.48 miles northwest of Greenville
  • Mid-scale Highway hotel
  • 9 suites in property
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From£71 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Litchfield West by IHG 4 Thunderbird Circle, Litchfield, IL 62056 Call ~24.49 miles northwest of Greenville
  • Three Star Rural property
  • Check-in: 15:00
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From£70 total
Very good 4.0 /5 Review Score Call BookMore Details
Best Western Plus Centralia Hotel & Suites 8145 Jolliff Bridge Rd., Centralia, IL 62801 Call ~28.09 miles southeast of Greenville
  • Midscale property
  • Check-in time: 03:00
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From£69 total
Very good 4.0 /5 Latest Reviews Call BookMore Details
Americas Best Value Inn : 200 East Noleman 200 East Noleman, Centralia, IL 62801 Call ~29.09 miles southeast of Greenville
  • Cheap property
  • Check-in time: 2:00 PM
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From£53 total
Very good 4.0 /5 Reviews Call BookMore Details
Motel 6 Troy Il 909 Edwardsville Rd., Troy, IL 62294 Call ~29.31 miles west of Greenville
  • Cheap property
  • Hotel has 48 rooms
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From£44 total
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites Salem near I-57 : 1800 West Main St. 1800 West Main St., Salem, IL 62881 Website Call ~29.38 miles southeast of Greenville
  • Economical Rural property
  • Hotel has 65 rooms
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From£61 total
Very good 4.0 /5 Latest Reviews Call BookMore Details
Best Western Troy Hotel in Troy 2020 Formosa Rd., Troy, IL 62294 Call ~29.44 miles west of Greenville
  • Mid-scale Rural property
  • 10 suites in hotel
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From£53 total
Average 3.5 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Troy by IHG in Troy 2011 Formosa Rd., Troy, IL 62294 Call ~29.51 miles west of Greenville
  • Affordable Highway property
  • Has environment-friendly policy See more
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From£74 total
Very good 4.5 /5 Reviews Call BookMore Details
Red Roof Inn St Louis - Troy, IL in Troy 2030 Formosa Rd., Troy, IL 62294 Call ~29.55 miles west of Greenville
  • Economy property
  • Fitness / Gym is on-site
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From£47 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Salem, Illinois 1812 West Main St., Salem, IL 62881 Call ~29.55 miles southeast of Greenville
  • Low priced hotel
  • 94 rooms in hotel
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From£41 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Troy IL/St. Louis Area : 910 Edwardsville Rd. 910 Edwardsville Rd., Troy, IL 62294 Call ~29.60 miles west of Greenville
  • Inexpensive Highway property
  • 2 floors in property
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From£56 total
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Salem 118 Woods Ln, Salem, IL 62881 Call ~29.63 miles southeast of Greenville
  • Low Cost Highway hotel
  • Has environment-friendly policy See more
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From£53 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Magnuson Grand Hotel And Conference Center : 19067 West Frontage Rd. 19067 West Frontage Rd., Raymond, IL 62560 Call ~29.70 miles northwest of Greenville
  • Mid-scale Rural property
  • Hotel has an eco-friendly policy Read more
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From£43 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Salem by IHG in Salem 102 Holiday Lane, Salem, IL 62881 Call ~29.89 miles southeast of Greenville
  • 3-star Highway hotel
  • 15 suites in property
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From£77 total
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Edwardsville by IHG 1000 Plummer Dr., Edwardsville, IL 62025 Call ~31.59 miles west of Greenville
  • Midscale Suburban hotel
  • 18 suites in hotel
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From£83 total
Very good 4.0 /5 Review Score Call BookMore Details
Country Hearth Inn & Suites Edwardsville St. Louis 1013 Plummer Dr., Edwardsville, IL 62025 Call ~31.66 miles west of Greenville
  • Affordable Rural property
  • 3 floors in property
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From£59 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
TownePlace Suites by Marriott St. Louis Edwardsville, IL - Edwardsville 6101 Center Grove Rd., Edwardsville, IL 62025 Call ~31.67 miles west of Greenville
  • Mid-scale Suburban property
  • Hotel has 91 rooms
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From£80 total
Very good 4.0 /5 Review Score Call BookMore Details
Best Western Plus MidAmerica Hotel : 9730 Hayden Dr. 9730 Hayden Dr., Mascoutah, IL 62258 Call ~32.05 miles southwest of Greenville
  • Affordable Suburban property
  • 85 rooms in property
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From£61 total
Very good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Okawville 812 North Henhouse Rd., Okawville, IL 62271 Call ~32.28 miles south of Greenville
  • Low Cost Rural property
  • 2 suites in hotel
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From£56 total
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Okawville : 812 North Hen House Rd. 812 North Hen House Rd., Okawville, IL 62271 Call ~32.28 miles south of Greenville
  • Two-star property
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From£53 total
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham O'fallon 1100 Eastgate Dr., Ofallon, IL 62269 Call ~33.41 miles southwest of Greenville
  • Inexpensive Suburban property
  • Gym / Fitness Center Available
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From£35 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn Edwardsville - St. Louis - Edwardsville 3080 South State Rte 157, Edwardsville, IL 62025 Call ~33.44 miles west of Greenville
  • Two star Highway hotel
  • 71 sleeping rooms in hotel
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From£53 total
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Inn Edwardsville - Edwardsville 3080 Il 157, Edwardsville, IL 62025 Call ~33.44 miles west of Greenville
  • Affordable Highway property
  • 74 rooms in property
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From£71 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites St. Louis Edwardsville - Glen Carbon 5723 Heritage Crossing Dr., Glen Carbon, IL 62034 Call ~33.74 miles west of Greenville
  • 3-star Suburban hotel
  • 72 sleeping rooms in hotel
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From£88 total
Very good 4.0 /5 Latest Reviews Call BookMore Details
Best Western U. S. Inn in Nashville 11640 State Route 127, Nashville, IL 62263 Call ~35.22 miles south of Greenville
  • Three Star Highway hotel
  • Check-in: 02:00
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From£54 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
Sleep Inn O Fallon Il - O'fallon 140 Venita Dr., O'fallon, IL 62269 Call ~35.35 miles southwest of Greenville
  • Midscale Suburban property
  • Check-in time: 4:00pm
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From£71 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites O'fallon / Shiloh An Ihg Hotel : 3396 Green Mount Crossing 3396 Green Mount Crossing, Shiloh, IL 62269 Call ~35.48 miles southwest of Greenville
  • 3 star Highway hotel
  • 80 rooms in hotel
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From£88 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites Ofallon St. Louis Area - O'fallon 116 Regency Park, O'fallon, IL 62269 Call ~35.51 miles southwest of Greenville
  • Low-priced Suburban property
  • Check-in time: 3:00 PM
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From£53 total
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn O'fallon Il 430 Regency Park, O'fallon, IL 62269 Call ~35.57 miles southwest of Greenville
  • 3 star Suburban hotel
  • 4 floors in hotel
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From£71 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis in O'fallon 136 Regency Park, O'fallon, IL 62269 Call ~35.59 miles southwest of Greenville
  • Two star Suburban hotel
  • Check in time: 3:00 PM
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From£53 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hilton Garden Inn St. Louis Shiloh / O'fallon Il 360 Regency Park, O'fallon, IL 62269 Call ~35.65 miles southwest of Greenville
  • Three Star Suburban hotel
  • Check in: 03:00 PM
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From£71 total
Average 3.0 /5 Review Score Call BookMore Details
Extended Stay America Select Suites - St. Louis - O' Fallon, IL 154 Regency Park, O'fallon, IL 62269 Call ~35.68 miles southwest of Greenville
  • Economical Highway property
  • 89 rooms in property
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From£34 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Welcome Suites 148 Regency Park, O'fallon, IL 62269 Call ~35.68 miles southwest of Greenville
  • Two star Suburban property
  • 89 rooms in hotel
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From£35 total
Very good 4.0 /5 Guest Reviews Call BookMore Details

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Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Pizza slices at Casey's was very good"
Score 5.0 / 5

Akia S., from 12-Jul-2026
"Quiet town"
Score 4.0 / 5

Quiet town and my Son plays Basketball for Greenville university.

Newton A., from 26-Feb-2026
"Great Diner!"
Score 4.0 / 5

Vicky's Cafe was awesome!! Very helpful and polite staff! Clean diner with great food!

Amy S., from 24-Aug-2025
"Dressed up Strip area."
Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025
"Quiet Area"
Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024
"Proximity to Carlyle"
Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024
"Greenville has some excellent museums!"
Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023
"Great Aquarium"
Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023
"College Campus"
Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023
"Loved It!"
Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022
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