Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels/Motels & Accommodations

Super 8 by Wyndham Greenville : 1700 State Route 127 1700 State Route 127, Greenville, IL 62246 Call
  • Cheap Rural hotel
  • Check in time: 12:00 PM
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From£45
Average 3.0 /5 Recent Reviews Call BookMore Details
SureStay by Best Western Greenville : 1731 South State Route 127 1731 South State Route 127, Greenville, IL 62246 Call
  • Low Cost Highway hotel
  • Free comp. breakfast
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From£31
Average 3.0 /5 Reviews Call BookMore Details
Comfort Inn & Suites Greenville I-70 2265 South State Route 127, Greenville, IL 62246 Website Call
  • Inexpensive Rural property
  • 2 meeting rooms in hotel
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From£40
Very good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Vandalia Il in Vandalia 21 Mattes Ave., Vandalia, IL 62471 Call ~15.52 miles east of Greenville
  • Mid-scale Highway hotel
  • Gym / Fitness Center Available
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From£60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Ramada by Wyndham Vandalia : 2707 Veterans Ave. 2707 Veterans Ave., Vandalia, IL 62471 Call ~15.77 miles east of Greenville
  • Two-star property
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From£45
Average 3.0 /5 Review Score Call BookMore Details
Americas Best Value Inn Vandalia - Vandalia 1500 North 6th St., Vandalia, IL 62471 Call ~17.45 miles east of Greenville
  • Economical Lake hotel
  • 44 rooms in hotel
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From£37
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Quality Inn & Suites Vandalia near I-70 and Hwy 51 1920 North Kennedy Blvd., Vandalia, IL 62471 Website Call ~17.57 miles east of Greenville
  • Cheap Highway hotel
  • 8 suites in hotel
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From£45
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 in Vandalia 1920 Kennedy Blvd., Vandalia, IL 62471 Call ~17.59 miles east of Greenville
  • Two star Rural hotel
  • Free breakfast available
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From£43
Very good 4.5 /5 Guest Reviews Call BookMore Details
Seasons Inn & Suites Highland 20 Central Blvd., Highland, IL 62249 Call ~17.74 miles southwest of Greenville
  • Economical property
  • Fitness / Gym is on-site
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From£49
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Mariner's Village Resort & Inn : 1 Resort Dr. 1 Resort Dr., Carlyle, IL 62231 Call ~18.34 miles south of Greenville
  • Low-priced Lake property
  • Check in: 15:00
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From£44
Very good 4.0 /5 Guest Reviews Call BookMore Details
Centerstone Inn & Suites - Carlyle 1371 William Rd., Carlyle, IL 62231 Call ~18.46 miles south of Greenville
  • 2-star property
  • 41 sleeping rooms in hotel
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From£45
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Super 8 by Wyndham Staunton - Staunton 1527 Herman Rd., Staunton, IL 62088 Call ~21.09 miles west of Greenville
  • Inexpensive property
  • Hotel has a green policy See more
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From£37
Very good 4.0 /5 Read Reviews Call BookMore Details
Innkeeper Motel 401 East State St., Hamel, IL 62046 Call ~23.07 miles west of Greenville
  • Midscale Lake hotel
  • Hotel has 24 rooms
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From£60
Average 3.0 /5 Guest Reviews Call BookMore Details
Americas Best Value Inn Litchfield - Litchfield 224 North Ohren Lane, Litchfield, IL 62056 Call ~24.10 miles northwest of Greenville
  • Low Cost hotel
  • Hotel has 2 floors
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From£45
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Litchfield, IL : 211 Ohren Ln 211 Ohren Ln, Litchfield, IL 62056 Call ~24.16 miles northwest of Greenville
  • 2 star Highway property
  • Check in: 11:00 AM
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From£45
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Baymont by Wyndham Litchfield : 1405 West Hudson Dr. 1405 West Hudson Dr., Litchfield, IL 62056 Call ~24.16 miles northwest of Greenville
  • Low Cost Highway property
  • Check in: 3:00 pm
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From£45
Very good 4.0 /5 Latest Reviews Call BookMore Details
Quality Inn Litchfield Route 66 1010 East Columbian Blvd. North, Litchfield, IL 62056 Website Call ~24.37 miles northwest of Greenville
  • 2 star Downtown hotel
  • 60 sleeping rooms in hotel
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From£52
Very good 4.5 /5 Reviews Call BookMore Details
Hampton Inn Litchfield 11 Thunderbird Cir, Litchfield, IL 62056 Call ~24.48 miles northwest of Greenville
  • Midscale Highway property
  • Check in time: 3:00pm
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From£60
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Holiday Inn Express & Suites Litchfield West by IHG in Litchfield 4 Thunderbird Circle, Litchfield, IL 62056 Call ~24.49 miles northwest of Greenville
  • Midscale Rural hotel
  • 79 rooms in hotel
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From£59
Very good 4.0 /5 Latest Reviews Call BookMore Details
Best Western Plus Centralia Hotel & Suites : 8145 Jolliff Bridge Rd. 8145 Jolliff Bridge Rd., Centralia, IL 62801 Call ~28.09 miles southeast of Greenville
  • 3 star property
  • 3 conference rooms in property
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From£58
Very good 4.0 /5 Guest Reviews Call BookMore Details
Americas Best Value Inn in Centralia 200 East Noleman, Centralia, IL 62801 Call ~29.09 miles southeast of Greenville
  • Two star property
  • Check in time: 2:00 PM
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From£45
Very good 4.0 /5 Guest Reviews Call BookMore Details
Motel 6 Troy Il 909 Edwardsville Rd., Troy, IL 62294 Call ~29.31 miles west of Greenville
  • Cheap property
  • Check-in: 15:00
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From£37
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Quality Inn & Suites Salem near I-57 in Salem 1800 West Main St., Salem, IL 62881 Website Call ~29.38 miles southeast of Greenville
  • 2-star Rural property
  • Free breakfast available
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From£52
Very good 4.0 /5 Guest Reviews Call BookMore Details
Best Western Troy Hotel 2020 Formosa Rd., Troy, IL 62294 Call ~29.44 miles west of Greenville
  • 3-star Rural hotel
  • Check in time: 03:00 PM
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From£45
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Holiday Inn Express Troy by IHG 2011 Formosa Rd., Troy, IL 62294 Call ~29.51 miles west of Greenville
  • Mid-scale Highway hotel
  • Hotel has 4 floors
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From£63
Very good 4.5 /5 Recent Reviews Call BookMore Details
Red Roof Inn St Louis - Troy, IL 2030 Formosa Rd., Troy, IL 62294 Call ~29.55 miles west of Greenville
  • 2-star property
  • Hotel has 3 floors
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From£40
Very good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Salem, Illinois - Salem 1812 West Main St., Salem, IL 62881 Call ~29.55 miles southeast of Greenville
  • Low-priced property
  • Gym is available on property
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From£35
Very good 4.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Troy IL/St. Louis Area 910 Edwardsville Rd., Troy, IL 62294 Call ~29.60 miles west of Greenville
  • Two star Highway hotel
  • Complimentary breakfast is offered
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From£47
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Salem : 118 Woods Ln 118 Woods Ln, Salem, IL 62881 Call ~29.63 miles southeast of Greenville
  • Economical Highway property
  • Hotel has a green policy See policy
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From£45
Average 3.0 /5 Recent Reviews Call BookMore Details
Magnuson Grand Hotel And Conference Center : 19067 West Frontage Rd. 19067 West Frontage Rd., Raymond, IL 62560 Call ~29.70 miles northwest of Greenville
  • Mid-scale Rural property
  • Hotel has a green policy See more
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From£37
Very good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Salem by IHG in Salem 102 Holiday Lane, Salem, IL 62881 Call ~29.89 miles southeast of Greenville
  • 3 star Highway property
  • Hotel has 15 suites
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From£65
Excellent 5.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Edwardsville by IHG : 1000 Plummer Dr. 1000 Plummer Dr., Edwardsville, IL 62025 Call ~31.59 miles west of Greenville
  • Affordable Suburban property
  • 2 meeting rooms in property
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From£71
Very good 4.0 /5 Guest Reviews Call BookMore Details
Country Hearth Inn & Suites Edwardsville St. Louis 1013 Plummer Dr., Edwardsville, IL 62025 Call ~31.66 miles west of Greenville
  • Affordable Rural hotel
  • Hotel has 39 rooms
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From£50
Very good 4.0 /5 Review Score Call BookMore Details
TownePlace Suites by Marriott St. Louis Edwardsville, IL 6101 Center Grove Rd., Edwardsville, IL 62025 Call ~31.67 miles west of Greenville
  • Mid-scale Suburban property
  • Gym is available on property
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From£67
Very good 4.0 /5 Read Reviews Call BookMore Details
Best Western Plus MidAmerica Hotel - Mascoutah 9730 Hayden Dr., Mascoutah, IL 62258 Call ~32.05 miles southwest of Greenville
  • Affordable Suburban hotel
  • Has environment-friendly policy See policy
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From£52
Very good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Okawville 812 North Henhouse Rd., Okawville, IL 62271 Call ~32.28 miles south of Greenville
  • Economy Rural property
  • Hotel has 38 rooms
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From£48
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Okawville - Okawville 812 North Hen House Rd., Okawville, IL 62271 Call ~32.28 miles south of Greenville
  • Low-priced property
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From£45
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Super 8 by Wyndham O'fallon 1100 Eastgate Dr., Ofallon, IL 62269 Call ~33.41 miles southwest of Greenville
  • Two star Suburban hotel
  • Hotel has 8 suites
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From£30
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Comfort Inn Edwardsville - St. Louis 3080 South State Rte 157, Edwardsville, IL 62025 Call ~33.44 miles west of Greenville
  • Two star Highway hotel
  • Check in time: 03:00 PM
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From£45
Average 3.0 /5 Review Score Call BookMore Details
Comfort Inn Edwardsville : 3080 Il 157 3080 Il 157, Edwardsville, IL 62025 Call ~33.44 miles west of Greenville
  • Mid-scale Highway hotel
  • Fitness / Gym is on-site
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From£60
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn & Suites St. Louis Edwardsville - Glen Carbon 5723 Heritage Crossing Dr., Glen Carbon, IL 62034 Call ~33.74 miles west of Greenville
  • Three Star Suburban hotel
  • Check in: 3pm
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From£74
Very good 4.0 /5 Latest Reviews Call BookMore Details
Best Western U. S. Inn : 11640 State Route 127 11640 State Route 127, Nashville, IL 62263 Call ~35.22 miles south of Greenville
  • 3 star Highway hotel
  • Hotel has 48 rooms
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From£48
Very good 4.0 /5 Read Reviews Call BookMore Details
Sleep Inn O Fallon Il : 140 Venita Dr. 140 Venita Dr., O'fallon, IL 62269 Call ~35.35 miles southwest of Greenville
  • Mid-scale Suburban hotel
  • Check in: 4:00pm
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From£60
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites O'fallon / Shiloh An Ihg Hotel - Shiloh 3396 Green Mount Crossing, Shiloh, IL 62269 Call ~35.48 miles southwest of Greenville
  • Mid-scale Highway hotel
  • Check in time: 3:00
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From£74
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Inn & Suites Ofallon St. Louis Area : 116 Regency Park 116 Regency Park, O'fallon, IL 62269 Call ~35.51 miles southwest of Greenville
  • Two-star Suburban property
  • Check in: 3:00 PM
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From£45
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn O'fallon Il 430 Regency Park, O'fallon, IL 62269 Call ~35.57 miles southwest of Greenville
  • Mid-scale Suburban property
  • Check in time: 3:00pm
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From£60
Very good 4.0 /5 Guest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis 136 Regency Park, O'fallon, IL 62269 Call ~35.59 miles southwest of Greenville
  • Low Cost Suburban hotel
  • Access to gym on-site
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From£45
Average 3.0 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn St. Louis Shiloh / O'fallon Il 360 Regency Park, O'fallon, IL 62269 Call ~35.65 miles southwest of Greenville
  • 3 star Suburban property
  • Hotel has 4 floors
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From£60
Average 3.0 /5 Review Score Call BookMore Details
Extended Stay America Select Suites - St. Louis - O' Fallon, IL 154 Regency Park, O'fallon, IL 62269 Call ~35.68 miles southwest of Greenville
  • 2 star Highway hotel
  • Hotel has 3 floors
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From£29
Average 3.0 /5 Read Reviews Call BookMore Details
Drury Inn St. Louis Collinsville 602 North Bluff Rd., Collinsville, IL 62234 Call ~35.68 miles west of Greenville
  • Three Star Suburban hotel
  • Has environment-friendly policy Read more
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From£67
Very good 4.0 /5 Read Reviews Call BookMore Details

Next: See My Greenville Hotels with Pricing

Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Quiet town"
Score 4.0 / 5

Quiet town and my Son plays Basketball for Greenville university.

Newton A., from 26-Feb-2026
"Great Diner!"
Score 4.0 / 5

Vicky's Cafe was awesome!! Very helpful and polite staff! Clean diner with great food!

Amy S., from 24-Aug-2025
"Dressed up Strip area."
Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025
"Quiet Area"
Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024
"Proximity to Carlyle"
Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024
"Greenville has some excellent museums!"
Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023
"Great Aquarium"
Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023
"College Campus"
Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023
"Loved It!"
Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022
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