Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels/Accommodations

Super 8 by Wyndham Greenville - Greenville 1700 State Route 127, Greenville, IL 62246 Call
  • Low-priced Rural property
  • Check-in time: 12:00 PM
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From£43
Average 3.0 /5 Recent Reviews Call BookMore Details
SureStay by Best Western Greenville 1731 South State Route 127, Greenville, IL 62246 Call
  • Two star Highway property
  • 2 floors in hotel
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From£30
Average 3.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn & Suites Greenville I-70 2265 South State Route 127, Greenville, IL 62246 Website Call
  • Cheap Rural property
  • Free comp. breakfast
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From£38
Very good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Vandalia Il in Vandalia 21 Mattes Ave., Vandalia, IL 62471 Call ~15.52 miles east of Greenville
  • 3-star Highway property
  • Hotel has a green policy Learn more
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From£58
Average 3.0 /5 Recent Reviews Call BookMore Details
Ramada by Wyndham Vandalia in Vandalia 2707 Veterans Ave., Vandalia, IL 62471 Call ~15.77 miles east of Greenville
  • Economical property
  • Check in: 11:00 AM
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From£43
Average 3.0 /5 Recent Reviews Call BookMore Details
Americas Best Value Inn Vandalia in Vandalia 1500 North 6th St., Vandalia, IL 62471 Call ~17.45 miles east of Greenville
  • Low-priced Lake property
  • Check-in: 3.00
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From£36
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 in Vandalia 1920 North Kennedy Blvd., Vandalia, IL 62471 Website Call ~17.57 miles east of Greenville
  • Two-star Highway hotel
  • 8 suites in property
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From£43
Very good 4.0 /5 Review Score Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 1920 Kennedy Blvd., Vandalia, IL 62471 Call ~17.59 miles east of Greenville
  • 2-star Rural property
  • Free comp. breakfast
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From£41
Very good 4.5 /5 Read Reviews Call BookMore Details
Seasons Inn & Suites Highland in Highland 20 Central Blvd., Highland, IL 62249 Call ~17.74 miles southwest of Greenville
  • 2-star property
  • Complimentary breakfast is offered
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From£47
Average 3.0 /5 Read Reviews Call BookMore Details
Mariner's Village Resort & Inn 1 Resort Dr., Carlyle, IL 62231 Call ~18.34 miles south of Greenville
  • 2 star Lake property
  • Hotel has 65 rooms
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From£43
Very good 4.0 /5 Latest Reviews Call BookMore Details
Centerstone Inn & Suites in Carlyle 1371 William Rd., Carlyle, IL 62231 Call ~18.46 miles south of Greenville
  • Low-priced property
  • 41 rooms in hotel
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From£43
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Staunton 1527 Herman Rd., Staunton, IL 62088 Call ~21.09 miles west of Greenville
  • Economical property
  • Free breakfast available
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From£36
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Innkeeper Motel in Hamel 401 East State St., Hamel, IL 62046 Call ~23.07 miles west of Greenville
  • 3-star Lake hotel
  • 2 floors in property
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From£58
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn Litchfield 224 North Ohren Lane, Litchfield, IL 62056 Call ~24.10 miles northwest of Greenville
  • Two-star property
  • Check-in: 15:00
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From£43
Poor 2.0 /5 Reviews Call BookMore Details
Motel 6 Litchfield, IL - Litchfield 211 Ohren Ln, Litchfield, IL 62056 Call ~24.16 miles northwest of Greenville
  • Economy Highway hotel
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From£43
Average 3.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Litchfield in Litchfield 1405 West Hudson Dr., Litchfield, IL 62056 Call ~24.16 miles northwest of Greenville
  • Cheap Highway hotel
  • Comp. Breakfast
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From£43
Very good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn Litchfield Route 66 - Litchfield 1010 East Columbian Blvd. North, Litchfield, IL 62056 Website Call ~24.37 miles northwest of Greenville
  • Two-star Downtown hotel
  • Access to gym on-site
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From£51
Very good 4.5 /5 Read Reviews Call BookMore Details
Hampton Inn Litchfield - Litchfield 11 Thunderbird Cir, Litchfield, IL 62056 Call ~24.48 miles northwest of Greenville
  • Mid-scale Highway hotel
  • Gym / Fitness Center Available
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From£58
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Litchfield West by IHG : 4 Thunderbird Circle 4 Thunderbird Circle, Litchfield, IL 62056 Call ~24.49 miles northwest of Greenville
  • Mid-scale Rural property
  • 4 floors in property
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From£57
Very good 4.0 /5 Review Score Call BookMore Details
Best Western Plus Centralia Hotel & Suites - Centralia 8145 Jolliff Bridge Rd., Centralia, IL 62801 Call ~28.09 miles southeast of Greenville
  • Three Star property
  • 17 suites in hotel
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From£57
Very good 4.0 /5 Review Score Call BookMore Details
Americas Best Value Inn 200 East Noleman, Centralia, IL 62801 Call ~29.09 miles southeast of Greenville
  • 2-star hotel
  • 57 sleeping rooms in hotel
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From£43
Very good 4.0 /5 Review Score Call BookMore Details
Motel 6 Troy Il : 909 Edwardsville Rd. 909 Edwardsville Rd., Troy, IL 62294 Call ~29.31 miles west of Greenville
  • Two star property
  • Hotel has 2 floors
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From£36
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites Salem near I-57 : 1800 West Main St. 1800 West Main St., Salem, IL 62881 Website Call ~29.38 miles southeast of Greenville
  • Cheap Rural property
  • Hotel has 3 floors
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From£50
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Best Western Troy Hotel : 2020 Formosa Rd. 2020 Formosa Rd., Troy, IL 62294 Call ~29.44 miles west of Greenville
  • 3 star Rural hotel
  • 65 rooms in hotel
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From£43
Average 3.5 /5 Read Reviews Call BookMore Details
Holiday Inn Express Troy by IHG - Troy 2011 Formosa Rd., Troy, IL 62294 Call ~29.51 miles west of Greenville
  • Affordable Highway hotel
  • Hotel has an eco-friendly policy Read more
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From£61
Very good 4.5 /5 Latest Reviews Call BookMore Details
Red Roof Inn St Louis - Troy, IL 2030 Formosa Rd., Troy, IL 62294 Call ~29.55 miles west of Greenville
  • Inexpensive hotel
  • Comp. Breakfast
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From£38
Very good 4.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Salem, Illinois - Salem 1812 West Main St., Salem, IL 62881 Call ~29.55 miles southeast of Greenville
  • Two star hotel
  • 94 rooms in hotel
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From£34
Very good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Troy IL/St. Louis Area 910 Edwardsville Rd., Troy, IL 62294 Call ~29.60 miles west of Greenville
  • Cheap Highway property
  • 2 floors in hotel
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From£46
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Salem : 118 Woods Ln 118 Woods Ln, Salem, IL 62881 Call ~29.63 miles southeast of Greenville
  • 2 star Highway hotel
  • 3 floors in hotel
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From£43
Average 3.0 /5 Reviews Call BookMore Details
Magnuson Grand Hotel And Conference Center in Raymond 19067 West Frontage Rd., Raymond, IL 62560 Call ~29.70 miles northwest of Greenville
  • Mid-scale Rural hotel
  • 8 meeting rooms in property
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From£35
Very good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Salem by IHG 102 Holiday Lane, Salem, IL 62881 Call ~29.89 miles southeast of Greenville
  • 3-star Highway property
  • 15 suites in property
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From£63
Excellent 5.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Edwardsville by IHG 1000 Plummer Dr., Edwardsville, IL 62025 Call ~31.59 miles west of Greenville
  • Mid-scale Suburban property
  • Hotel has 2 meeting rooms
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From£68
Very good 4.0 /5 Review Score Call BookMore Details
Country Hearth Inn & Suites Edwardsville St. Louis in Edwardsville 1013 Plummer Dr., Edwardsville, IL 62025 Call ~31.66 miles west of Greenville
  • Affordable Rural property
  • Gym is available on property
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From£49
Very good 4.0 /5 Reviews Call BookMore Details
TownePlace Suites by Marriott St. Louis Edwardsville, IL in Edwardsville 6101 Center Grove Rd., Edwardsville, IL 62025 Call ~31.67 miles west of Greenville
  • 3 star Suburban property
  • 91 rooms in hotel
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From£65
Very good 4.0 /5 Read Reviews Call BookMore Details
Best Western Plus MidAmerica Hotel 9730 Hayden Dr., Mascoutah, IL 62258 Call ~32.05 miles southwest of Greenville
  • Three Star Suburban hotel
  • Has environment-friendly policy See more
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From£50
Very good 4.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Okawville in Okawville 812 North Henhouse Rd., Okawville, IL 62271 Call ~32.28 miles south of Greenville
  • Two star Rural property
  • 2 suites in hotel
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From£46
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Okawville 812 North Hen House Rd., Okawville, IL 62271 Call ~32.28 miles south of Greenville
  • Cheap property
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From£43
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham O'fallon 1100 Eastgate Dr., Ofallon, IL 62269 Call ~33.41 miles southwest of Greenville
  • 2 star Suburban hotel
  • Hotel has an eco-friendly policy See more
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From£29
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn Edwardsville - St. Louis - Edwardsville 3080 South State Rte 157, Edwardsville, IL 62025 Website Call ~33.44 miles west of Greenville
  • Low-priced Highway property
  • Hotel has 4 suites
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From£43
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites St. Louis Edwardsville - Glen Carbon 5723 Heritage Crossing Dr., Glen Carbon, IL 62034 Call ~33.74 miles west of Greenville
  • 3 star Suburban hotel
  • Fitness / Gym is on-site
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From£72
Very good 4.0 /5 Read Reviews Call BookMore Details
Best Western U. S. Inn 11640 State Route 127, Nashville, IL 62263 Call ~35.22 miles south of Greenville
  • Mid-scale Highway hotel
  • Hotel has 48 rooms
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From£45
Very good 4.0 /5 Recent Reviews Call BookMore Details
Sleep Inn O Fallon Il 140 Venita Dr., O'fallon, IL 62269 Call ~35.35 miles southwest of Greenville
  • Affordable Suburban property
  • Free breakfast available
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From£58
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites O'fallon / Shiloh by IHG 3396 Green Mt. Crossing Dr., Shiloh, IL 62269 Call ~35.49 miles southwest of Greenville
  • 3-star Highway property
  • Fitness + Health Center
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From£58
Average 3.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn & Suites Ofallon St. Louis Area 116 Regency Park, O'fallon, IL 62269 Call ~35.51 miles southwest of Greenville
  • Economical Suburban property
  • 2 meeting rooms in hotel
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From£43
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn O'fallon Il - O'fallon 430 Regency Park, O'fallon, IL 62269 Call ~35.57 miles southwest of Greenville
  • Three Star Suburban hotel
  • Hotel has 4 floors
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From£58
Very good 4.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis in O'fallon 136 Regency Park, O'fallon, IL 62269 Call ~35.59 miles southwest of Greenville
  • 2 star Suburban hotel
  • Free breakfast available
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From£43
Average 3.0 /5 Reviews Call BookMore Details
Hilton Garden Inn St. Louis Shiloh / O'fallon Il in O'fallon 360 Regency Park, O'fallon, IL 62269 Call ~35.65 miles southwest of Greenville
  • Affordable Suburban property
  • Check-in: 03:00 PM
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From£58
Average 3.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Select Suites - St. Louis - O' Fallon, IL 154 Regency Park, O'fallon, IL 62269 Call ~35.68 miles southwest of Greenville
  • Inexpensive Highway property
  • 89 rooms in property
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From£28
Average 3.0 /5 Hotel Reviews Call BookMore Details
Welcome Suites in O'fallon 148 Regency Park, O'fallon, IL 62269 Call ~35.68 miles southwest of Greenville
  • Two star Suburban property
  • Fitness / Gym is on-site
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From£29
Very good 4.0 /5 Review Score Call BookMore Details
Towneplace Place Suites by Marriott St. Louis O Fallon Illinois - Ofallon 445 Regency Park Dr., Ofallon, IL 62269 Call ~35.68 miles southwest of Greenville
  • 3-star hotel
  • Hotel has 89 suites
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From£65
Very good 4.0 /5 Review Score Call BookMore Details

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Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Great Diner!"
Score 4.0 / 5

Vicky's Cafe was awesome!! Very helpful and polite staff! Clean diner with great food!

Amy S., from 24-Aug-2025
"Dressed up Strip area."
Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025
"Quiet Area"
Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024
"Proximity to Carlyle"
Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024
"Greenville has some excellent museums!"
Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023
"Great Aquarium"
Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023
"College Campus"
Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023
"Loved It!"
Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022
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