Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels/Accommodations

Super 8 by Wyndham Greenville
+1-888-389-4121
1700 State Route 127, Greenville, IL 62246 +1-888-389-4121
  • Cheap Rural property
From£44
Average 3.0 /5 Guest Reviews Call BookMore Details
SureStay by Best Western Greenville - Greenville
+1-888-675-2083
1731 South State Route 127, Greenville, IL 62246 +1-888-675-2083
  • Two-star Highway hotel
  • Free comp. breakfast
From£31
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites Greenville I-70
+1-800-716-8490
2265 South State Route 127, Greenville, IL 62246 Website +1-800-716-8490
  • Low Cost Rural hotel
  • Check-in time: 3:00 PM
From£39
Very good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Vandalia Il
+1-800-805-5223
21 Mattes Ave., Vandalia, IL 62471 +1-800-805-5223 ~15.52 miles east of Greenville
  • Mid-scale Highway property
  • Check-in: 3:00 PM
From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Ramada by Wyndham Vandalia in Vandalia
+1-888-965-1860
2707 Veterans Ave., Vandalia, IL 62471 +1-888-965-1860 ~15.77 miles east of Greenville
  • Two star property
  • Check in time: 11:00 AM
From£44
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn Vandalia - Vandalia
+1-888-788-5576
1500 North 6th St., Vandalia, IL 62471 +1-888-788-5576 ~17.45 miles east of Greenville
  • Low-priced Lake hotel
  • 2 floors in hotel
From£37
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 - Vandalia
+1-888-897-9207
1920 North Kennedy Blvd., Vandalia, IL 62471 Website +1-888-897-9207 ~17.57 miles east of Greenville
  • 2-star Highway property
  • 2 floors in property
From£44
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 in Vandalia
+1-888-311-4278
1920 Kennedy Blvd., Vandalia, IL 62471 +1-888-311-4278 ~17.59 miles east of Greenville
  • Economy Rural hotel
  • Hotel has an eco-friendly policy See more
From£42
Very good 4.5 /5 Recent Reviews Call BookMore Details
Seasons Inn & Suites Highland
+1-888-469-4795
20 Central Blvd., Highland, IL 62249 +1-888-469-4795 ~17.74 miles southwest of Greenville
  • Economy property
  • 60 rooms in property
From£48
Average 3.0 /5 Latest Reviews Call BookMore Details
Mariner's Village Resort & Inn : 1 Resort Dr.
+1-888-734-9421
1 Resort Dr., Carlyle, IL 62231 +1-888-734-9421 ~18.34 miles south of Greenville
  • Low priced Lake property
  • Complimentary breakfast is offered
From£43
Very good 4.0 /5 Guest Reviews Call BookMore Details
Centerstone Inn & Suites : 1371 William Rd.
+1-888-841-5292
1371 William Rd., Carlyle, IL 62231 +1-888-841-5292 ~18.46 miles south of Greenville
  • Economical property
  • Hotel has 41 rooms
From£44
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Staunton
+1-888-455-5160
1527 Herman Rd., Staunton, IL 62088 +1-888-455-5160 ~21.09 miles west of Greenville
  • Inexpensive hotel
  • 2 floors in property
From£37
Very good 4.0 /5 Reviews Call BookMore Details
Innkeeper Motel
+1-888-965-8297
401 East State St., Hamel, IL 62046 +1-888-965-8297 ~23.07 miles west of Greenville
  • 3-star Lake property
  • Hotel has 2 floors
From£59
Average 3.0 /5 Guest Reviews Call BookMore Details
Americas Best Value Inn Litchfield in Litchfield
+1-888-906-6358
224 North Ohren Lane, Litchfield, IL 62056 +1-888-906-6358 ~24.10 miles northwest of Greenville
  • Low priced hotel
  • Free breakfast
Motel 6 Litchfield, IL
+1-888-749-6785
211 Ohren Ln, Litchfield, IL 62056 +1-888-749-6785 ~24.16 miles northwest of Greenville
  • Cheap Highway hotel
  • Check-in: 11:00 AM
From£44
Average 3.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Litchfield in Litchfield
+1-888-878-9982
1405 West Hudson Dr., Litchfield, IL 62056 +1-888-878-9982 ~24.16 miles northwest of Greenville
  • Low Cost Highway hotel
  • Gym / Fitness Center Available
From£44
Very good 4.0 /5 Reviews Call BookMore Details
Quality Inn Litchfield Route 66 : 1010 East Columbian Blvd. North
+1-888-389-4485
1010 East Columbian Blvd. North, Litchfield, IL 62056 Website +1-888-389-4485 ~24.37 miles northwest of Greenville
  • 2-star Downtown property
  • Check-in time: 3:00 PM
From£52
Very good 4.5 /5 Recent Reviews Call BookMore Details
Hampton Inn Litchfield
+1-888-389-4121
11 Thunderbird Cir, Litchfield, IL 62056 +1-888-389-4121 ~24.48 miles northwest of Greenville
  • Three Star Highway hotel
  • Fitness + Health Center
From£59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Litchfield West by IHG
+1-888-675-2083
4 Thunderbird Circle, Litchfield, IL 62056 +1-888-675-2083 ~24.49 miles northwest of Greenville
  • Three Star Rural property
  • 79 rooms in hotel
From£58
Very good 4.0 /5 Latest Reviews Call BookMore Details
Best Western Plus Centralia Hotel & Suites in Centralia
+1-800-716-8490
8145 Jolliff Bridge Rd., Centralia, IL 62801 +1-800-716-8490 ~28.09 miles southeast of Greenville
  • Mid-scale hotel
  • Hotel has 61 rooms
From£58
Very good 4.0 /5 Read Reviews Call BookMore Details
Americas Best Value Inn : 200 East Noleman
+1-800-805-5223
200 East Noleman, Centralia, IL 62801 +1-800-805-5223 ~29.09 miles southeast of Greenville
  • Low-priced property
  • 4 floors in property
From£44
Very good 4.0 /5 Read Reviews Call BookMore Details
Motel 6 Troy Il : 909 Edwardsville Rd.
+1-888-965-1860
909 Edwardsville Rd., Troy, IL 62294 +1-888-965-1860 ~29.31 miles west of Greenville
  • Cheap hotel
  • Check-in time: 15:00
From£37
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Salem near I-57
+1-888-788-5576
1800 West Main St., Salem, IL 62881 Website +1-888-788-5576 ~29.38 miles southeast of Greenville
  • Economy Rural property
  • 65 rooms in property
From£51
Very good 4.0 /5 Reviews Call BookMore Details
Best Western Troy Hotel in Troy
+1-888-897-9207
2020 Formosa Rd., Troy, IL 62294 +1-888-897-9207 ~29.44 miles west of Greenville
  • Three Star Rural hotel
  • Gym is available on property
From£44
Average 3.5 /5 Read Reviews Call BookMore Details
Holiday Inn Express Troy by IHG
+1-888-311-4278
2011 Formosa Rd., Troy, IL 62294 +1-888-311-4278 ~29.51 miles west of Greenville
  • Affordable Highway hotel
  • 2 meeting rooms in property
From£62
Very good 4.5 /5 Guest Reviews Call BookMore Details
Red Roof Inn St Louis - Troy, IL
+1-888-469-4795
2030 Formosa Rd., Troy, IL 62294 +1-888-469-4795 ~29.55 miles west of Greenville
  • Economy hotel
  • Fitness / Gym is on-site
From£39
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Salem, Illinois
+1-888-734-9421
1812 West Main St., Salem, IL 62881 +1-888-734-9421 ~29.55 miles southeast of Greenville
  • Low Cost hotel
  • Hotel has 94 rooms
From£35
Very good 4.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Troy IL/St. Louis Area
+1-888-841-5292
910 Edwardsville Rd., Troy, IL 62294 +1-888-841-5292 ~29.60 miles west of Greenville
  • Two-star Highway hotel
  • Check in: 03:00 PM
From£46
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Salem
+1-888-455-5160
118 Woods Ln, Salem, IL 62881 +1-888-455-5160 ~29.63 miles southeast of Greenville
  • Inexpensive Highway hotel
  • Hotel has a green policy See policy
From£44
Average 3.0 /5 Read Reviews Call BookMore Details
Magnuson Grand Hotel And Conference Center - Raymond
+1-888-965-8297
19067 West Frontage Rd., Raymond, IL 62560 +1-888-965-8297 ~29.70 miles northwest of Greenville
  • Mid-scale Rural property
  • Free breakfast
From£36
Very good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Salem by Ihg in Salem
+1-888-906-6358
102 Holiday Lane, Salem, IL 62881 +1-888-906-6358 ~29.89 miles southeast of Greenville
  • 3-star Highway property
  • 86 sleeping rooms in hotel
From£64
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Edwardsville by IHG : 1000 Plummer Dr.
+1-888-749-6785
1000 Plummer Dr., Edwardsville, IL 62025 +1-888-749-6785 ~31.59 miles west of Greenville
  • 3 star Suburban property
  • Fitness / Gym is on-site
From£70
Very good 4.0 /5 Latest Reviews Call BookMore Details
Country Hearth Inn & Suites Edwardsville St. Louis
+1-888-878-9982
1013 Plummer Dr., Edwardsville, IL 62025 +1-888-878-9982 ~31.66 miles west of Greenville
  • 3-star Rural hotel
  • 39 rooms in hotel
From£49
Very good 4.0 /5 Review Score Call BookMore Details
TownePlace Suites by Marriott St. Louis Edwardsville, IL
+1-888-389-4485
6101 Center Grove Rd., Edwardsville, IL 62025 +1-888-389-4485 ~31.67 miles west of Greenville
  • Mid-scale Suburban hotel
  • Fitness + Health Center
From£67
Very good 4.0 /5 Recent Reviews Call BookMore Details
Best Western Plus MidAmerica Hotel - Mascoutah
+1-888-389-4121
9730 Hayden Dr., Mascoutah, IL 62258 +1-888-389-4121 ~32.05 miles southwest of Greenville
  • Midscale Suburban property
  • Fitness center on property
From£51
Very good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Okawville
+1-888-675-2083
812 North Henhouse Rd., Okawville, IL 62271 +1-888-675-2083 ~32.28 miles south of Greenville
  • Two star Rural property
  • Check-in time: 2pm
From£47
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Okawville
+1-800-716-8490
812 North Hen House Rd., Okawville, IL 62271 +1-800-716-8490 ~32.28 miles south of Greenville
  • Economical property
From£44
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham O'fallon
+1-800-805-5223
1100 Eastgate Dr., Ofallon, IL 62269 +1-800-805-5223 ~33.41 miles southwest of Greenville
  • Economy Suburban hotel
  • Access to gym on-site
From£29
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn Edwardsville - St. Louis : 3080 South State Rte 157
+1-888-965-1860
3080 South State Rte 157, Edwardsville, IL 62025 Website +1-888-965-1860 ~33.44 miles west of Greenville
  • Two star Highway property
  • Free breakfast available
From£44
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites St. Louis Edwardsville : 5723 Heritage Crossing Dr.
+1-888-788-5576
5723 Heritage Crossing Dr., Glen Carbon, IL 62034 +1-888-788-5576 ~33.74 miles west of Greenville
  • Three Star Suburban property
  • Free breakfast
From£73
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Best Western U. S. Inn - Nashville
+1-888-897-9207
11640 State Route 127, Nashville, IL 62263 +1-888-897-9207 ~35.22 miles south of Greenville
  • Midscale Highway hotel
  • 2 floors in property
From£47
Very good 4.0 /5 Read Reviews Call BookMore Details
Sleep Inn O Fallon Il
+1-888-311-4278
140 Venita Dr., O'fallon, IL 62269 +1-888-311-4278 ~35.35 miles southwest of Greenville
  • Mid-scale Suburban hotel
  • Check-in: 4:00pm
From£59
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG
+1-888-469-4795
3396 Green Mt. Crossing Dr., Shiloh, IL 62269 +1-888-469-4795 ~35.49 miles southwest of Greenville
  • 3-star Highway hotel
  • Access to gym on-site
From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites Ofallon St. Louis Area
+1-888-734-9421
116 Regency Park, O'fallon, IL 62269 +1-888-734-9421 ~35.51 miles southwest of Greenville
  • Economy Suburban property
  • Fitness / Gym is on-site
From£44
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn O'fallon Il : 430 Regency Park
+1-888-841-5292
430 Regency Park, O'fallon, IL 62269 +1-888-841-5292 ~35.57 miles southwest of Greenville
  • Midscale Suburban property
  • Check-in time: 3:00pm
From£59
Very good 4.0 /5 Latest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis : 136 Regency Park
+1-888-455-5160
136 Regency Park, O'fallon, IL 62269 +1-888-455-5160 ~35.59 miles southwest of Greenville
  • Low-priced Suburban hotel
  • Free breakfast
From£44
Average 3.0 /5 Read Reviews Call BookMore Details
Hilton Garden Inn St. Louis Shiloh / O'fallon Il
+1-888-965-8297
360 Regency Park, O'fallon, IL 62269 +1-888-965-8297 ~35.65 miles southwest of Greenville
  • Affordable Suburban hotel
  • Check-in: 03:00 PM
From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Extended Stay America Select Suites - St. Louis - O' Fallon, IL
+1-888-906-6358
154 Regency Park, O'fallon, IL 62269 +1-888-906-6358 ~35.68 miles southwest of Greenville
  • Low priced Highway hotel
  • Check in time: 3:00 PM
From£29
Average 3.0 /5 Recent Reviews Call BookMore Details
Welcome Suites : 148 Regency Park
+1-888-749-6785
148 Regency Park, O'fallon, IL 62269 +1-888-749-6785 ~35.68 miles southwest of Greenville
  • 2 star Suburban property
  • 89 sleeping rooms in hotel
From£29
Very good 4.0 /5 Latest Reviews Call BookMore Details
Towneplace Place Suites by Marriott St. Louis O Fallon Illinois - Ofallon
+1-888-878-9982
445 Regency Park Dr., Ofallon, IL 62269 +1-888-878-9982 ~35.68 miles southwest of Greenville
  • 3-star property
  • 89 rooms in property
From£67
Very good 4.0 /5 Reviews Call BookMore Details

Next: See My Greenville Hotels with Pricing

Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Great Diner!"
Score 4.0 / 5

Vicky's Cafe was awesome!! Very helpful and polite staff! Clean diner with great food!

Amy S., from 24-Aug-2025
"Dressed up Strip area."
Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025
"Quiet Area"
Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024
"Proximity to Carlyle"
Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024
"Greenville has some excellent museums!"
Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023
"Great Aquarium"
Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023
"College Campus"
Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023
"Loved It!"
Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022
Back to Top