Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels/Motels & Accommodations

Super 8 by Wyndham Greenville - Greenville
+1-888-389-4121
1700 State Route 127, Greenville, IL 62246 +1-888-389-4121
  • Low priced Rural property
  • Check-in: 12:00 PM
From£43
Average 3.0 /5 Review Score Call BookMore Details
SureStay by Best Western Greenville - Greenville
+1-888-675-2083
1731 South State Route 127, Greenville, IL 62246 +1-888-675-2083
  • Economical Highway hotel
  • Check in time: 04:00
From£30
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Inn & Suites Greenville I-70 - Greenville
+1-800-716-8490
2265 South State Route 127, Greenville, IL 62246 Website +1-800-716-8490
  • Inexpensive Rural hotel
  • Complimentary breakfast is offered
From£38
Very good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Vandalia Il in Vandalia
+1-800-805-5223
21 Mattes Ave., Vandalia, IL 62471 +1-800-805-5223 ~15.54 miles east of Greenville
  • 3-star Highway hotel
  • Hotel has 15 suites
From£58
Average 3.0 /5 Hotel Reviews Call BookMore Details
Ramada by Wyndham Vandalia
+1-888-965-1860
2707 Veterans Ave., Vandalia, IL 62471 +1-888-965-1860 ~15.78 miles east of Greenville
  • Low priced hotel
  • Check in time: 11:00 AM
From£43
Average 3.0 /5 Review Score Call BookMore Details
Americas Best Value Inn Vandalia : 1500 North 6th St.
+1-888-788-5576
1500 North 6th St., Vandalia, IL 62471 +1-888-788-5576 ~17.47 miles east of Greenville
  • Cheap Lake hotel
  • Hotel has 44 rooms
From£36
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 : 1920 North Kennedy Blvd.
+1-888-897-9207
1920 North Kennedy Blvd., Vandalia, IL 62471 Website +1-888-897-9207 ~17.58 miles east of Greenville
  • Economy Highway hotel
  • 2 meeting rooms in property
From£43
Very good 4.0 /5 Review Score Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 : 1920 Kennedy Blvd.
+1-888-311-4278
1920 Kennedy Blvd., Vandalia, IL 62471 +1-888-311-4278 ~17.61 miles east of Greenville
  • 2-star Rural property
  • Hotel has an eco-friendly policy Learn more
From£41
Very good 4.5 /5 Reviews Call BookMore Details
Seasons Inn & Suites : 20 Central Blvd.
+1-888-469-4795
20 Central Blvd., Highland, IL 62249 +1-888-469-4795 ~17.78 miles southwest of Greenville
  • Two-star hotel
  • Hotel has 3 floors
From£47
Average 3.0 /5 Latest Reviews Call BookMore Details
Mariner's Village Resort & Inn in Carlyle
+1-888-734-9421
1 Resort Dr., Carlyle, IL 62231 +1-888-734-9421 ~18.37 miles south of Greenville
  • 2 star Lake property
  • 65 sleeping rooms in hotel
From£43
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Centerstone Inn & Suites : 1371 William Rd.
+1-888-841-5292
1371 William Rd., Carlyle, IL 62231 +1-888-841-5292 ~18.49 miles south of Greenville
  • Two-star hotel
  • Hotel has 2 floors
From£43
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Staunton - Staunton
+1-888-455-5160
1527 Herman Rd., Staunton, IL 62088 +1-888-455-5160 ~21.11 miles west of Greenville
  • Inexpensive property
  • Check in time: 2:00 PM
From£36
Very good 4.0 /5 Guest Reviews Call BookMore Details
Innkeeper Motel
+1-888-965-8297
401 East State St., Hamel, IL 62046 +1-888-965-8297 ~23.11 miles west of Greenville
  • Affordable Lake property
  • Check in: 2:00 PM
From£58
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn Litchfield - Litchfield
+1-888-906-6358
224 North Ohren Lane, Litchfield, IL 62056 +1-888-906-6358 ~24.12 miles northwest of Greenville
  • Inexpensive property
  • 65 rooms in property
From£43
Poor 2.0 /5 Reviews Call BookMore Details
Motel 6 Litchfield, IL : 211 Ohren Ln
+1-888-749-6785
211 Ohren Ln, Litchfield, IL 62056 +1-888-749-6785 ~24.18 miles northwest of Greenville
  • Economy Highway hotel
  • Check in: 11:00 AM
From£43
Average 3.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Litchfield
+1-888-878-9982
1405 West Hudson Dr., Litchfield, IL 62056 +1-888-878-9982 ~24.18 miles northwest of Greenville
  • 2 star Highway property
  • Access to gym on-site
From£43
Very good 4.0 /5 Latest Reviews Call BookMore Details
Quality Inn Litchfield Route 66 - Litchfield
+1-888-389-4485
1010 East Columbian Blvd. North, Litchfield, IL 62056 Website +1-888-389-4485 ~24.39 miles northwest of Greenville
  • Two-star Downtown property
  • Gym is available on property
From£51
Very good 4.5 /5 Read Reviews Call BookMore Details
Hampton Inn Litchfield
+1-888-389-4121
11 Thunderbird Cir, Litchfield, IL 62056 +1-888-389-4121 ~24.50 miles northwest of Greenville
  • Midscale Highway hotel
  • 9 suites in hotel
From£58
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Litchfield West by IHG : 4 Thunderbird Circle
+1-888-675-2083
4 Thunderbird Circle, Litchfield, IL 62056 +1-888-675-2083 ~24.50 miles northwest of Greenville
  • Affordable Rural hotel
  • Check in: 15:00
From£57
Very good 4.0 /5 Latest Reviews Call BookMore Details
Best Western Plus Centralia Hotel & Suites
+1-800-716-8490
8145 Jolliff Bridge Rd., Centralia, IL 62801 +1-800-716-8490 ~28.15 miles southeast of Greenville
  • Three Star property
  • 4 floors in hotel
From£56
Very good 4.0 /5 Guest Reviews Call BookMore Details
Americas Best Value Inn : 200 East Noleman
+1-800-805-5223
200 East Noleman, Centralia, IL 62801 +1-800-805-5223 ~29.16 miles southeast of Greenville
  • 2-star hotel
  • Comp. Breakfast
From£43
Very good 4.0 /5 Latest Reviews Call BookMore Details
Motel 6 Troy Il
+1-888-965-1860
909 Edwardsville Rd., Troy, IL 62294 +1-888-965-1860 ~29.38 miles west of Greenville
  • Two star hotel
  • Check-in time: 15:00
From£36
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Salem near I-57 - Salem
+1-888-788-5576
1800 West Main St., Salem, IL 62881 Website +1-888-788-5576 ~29.46 miles southeast of Greenville
  • 2-star Rural hotel
  • 20 suites in hotel
From£50
Very good 4.0 /5 Latest Reviews Call BookMore Details
Best Western Troy Hotel - Troy
+1-888-897-9207
2020 Formosa Rd., Troy, IL 62294 +1-888-897-9207 ~29.52 miles west of Greenville
  • Affordable Rural hotel
  • 65 rooms in property
From£43
Average 3.5 /5 Guest Reviews Call BookMore Details
Holiday Inn Express Troy by IHG
+1-888-311-4278
2011 Formosa Rd., Troy, IL 62294 +1-888-311-4278 ~29.58 miles west of Greenville
  • Mid-scale Highway property
  • 4 floors in property
From£61
Very good 4.5 /5 Guest Reviews Call BookMore Details
Red Roof Inn St Louis - Troy, IL
+1-888-469-4795
2030 Formosa Rd., Troy, IL 62294 +1-888-469-4795 ~29.62 miles west of Greenville
  • 2 star hotel
  • Free breakfast available
From£38
Very good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Salem, Illinois in Salem
+1-888-734-9421
1812 West Main St., Salem, IL 62881 +1-888-734-9421 ~29.63 miles southeast of Greenville
  • Cheap hotel
  • Check-in time: 3:00pm
From£34
Very good 4.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Troy IL/St. Louis Area - Troy
+1-888-841-5292
910 Edwardsville Rd., Troy, IL 62294 +1-888-841-5292 ~29.67 miles west of Greenville
  • Cheap Highway property
  • Hotel has 61 rooms
From£45
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Salem : 118 Woods Ln
+1-888-455-5160
118 Woods Ln, Salem, IL 62881 +1-888-455-5160 ~29.71 miles southeast of Greenville
  • Low Cost Highway hotel
  • 3 floors in hotel
From£43
Average 3.0 /5 Latest Reviews Call BookMore Details
Magnuson Grand Hotel And Conference Center
+1-888-965-8297
19067 West Frontage Rd., Raymond, IL 62560 +1-888-965-8297 ~29.73 miles northwest of Greenville
  • 3 star Rural hotel
  • 8 meeting rooms in hotel
From£35
Very good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Salem by IHG
+1-888-906-6358
102 Holiday Lane, Salem, IL 62881 +1-888-906-6358 ~29.97 miles southeast of Greenville
  • 3 star Highway property
  • Free comp. breakfast
From£63
Excellent 5.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Edwardsville by IHG - Edwardsville
+1-888-749-6785
1000 Plummer Dr., Edwardsville, IL 62025 +1-888-749-6785 ~31.66 miles west of Greenville
  • Affordable Suburban hotel
  • 18 suites in hotel
From£68
Very good 4.0 /5 Read Reviews Call BookMore Details
Country Hearth Inn & Suites Edwardsville St. Louis : 1013 Plummer Dr.
+1-888-878-9982
1013 Plummer Dr., Edwardsville, IL 62025 +1-888-878-9982 ~31.73 miles west of Greenville
  • Three Star Rural property
  • 13 suites in hotel
From£48
Very good 4.0 /5 Latest Reviews Call BookMore Details
TownePlace Suites by Marriott St. Louis Edwardsville, IL in Edwardsville
+1-888-389-4485
6101 Center Grove Rd., Edwardsville, IL 62025 +1-888-389-4485 ~31.74 miles west of Greenville
  • Mid-scale Suburban hotel
  • Hotel has 18 suites
From£65
Very good 4.0 /5 Guest Reviews Call BookMore Details
Best Western Plus MidAmerica Hotel - Mascoutah
+1-888-389-4121
9730 Hayden Dr., Mascoutah, IL 62258 +1-888-389-4121 ~32.13 miles southwest of Greenville
  • Mid-scale Suburban property
  • Fitness + Health Center
From£50
Very good 4.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Okawville - Okawville
+1-888-675-2083
812 North Henhouse Rd., Okawville, IL 62271 +1-888-675-2083 ~32.34 miles south of Greenville
  • Inexpensive Rural property
  • Check in: 2pm
From£46
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Okawville in Okawville
+1-800-716-8490
812 North Hen House Rd., Okawville, IL 62271 +1-800-716-8490 ~32.34 miles south of Greenville
  • 2-star hotel
From£43
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham O'fallon
+1-800-805-5223
1100 Eastgate Dr., Ofallon, IL 62269 +1-800-805-5223 ~33.50 miles southwest of Greenville
  • Inexpensive Suburban property
  • Fitness center on property
From£29
Average 3.0 /5 Review Score Call BookMore Details
Comfort Inn Edwardsville - St. Louis : 3080 South State Rte 157
+1-888-965-1860
3080 South State Rte 157, Edwardsville, IL 62025 Website +1-888-965-1860 ~33.52 miles west of Greenville
  • Economical Highway property
  • 4 floors in hotel
From£43
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn & Suites St. Louis Edwardsville in Glen Carbon
+1-888-788-5576
5723 Heritage Crossing Dr., Glen Carbon, IL 62034 +1-888-788-5576 ~33.82 miles west of Greenville
  • Three Star Suburban hotel
  • Check-in time: 3pm
From£72
Very good 4.0 /5 Read Reviews Call BookMore Details
Best Western U. S. Inn - Nashville
+1-888-897-9207
11640 State Route 127, Nashville, IL 62263 +1-888-897-9207 ~35.27 miles south of Greenville
  • Affordable Highway property
  • Hotel has 2 floors
From£46
Very good 4.0 /5 Recent Reviews Call BookMore Details
Sleep Inn O Fallon Il - O'fallon
+1-888-311-4278
140 Venita Dr., O'fallon, IL 62269 +1-888-311-4278 ~35.45 miles southwest of Greenville
  • 3-star Suburban property
  • Access to gym on-site
From£58
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG : 3396 Green Mt. Crossing Dr.
+1-888-469-4795
3396 Green Mt. Crossing Dr., Shiloh, IL 62269 +1-888-469-4795 ~35.59 miles southwest of Greenville
  • Mid-scale Highway property
  • 3 floors in property
From£58
Average 3.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn & Suites Ofallon St. Louis Area in O'fallon
+1-888-734-9421
116 Regency Park, O'fallon, IL 62269 +1-888-734-9421 ~35.62 miles southwest of Greenville
  • Cheap Suburban property
  • Check-in: 3:00 PM
From£43
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn O'fallon Il
+1-888-841-5292
430 Regency Park, O'fallon, IL 62269 +1-888-841-5292 ~35.67 miles southwest of Greenville
  • Midscale Suburban hotel
  • Check in: 3:00pm
From£58
Very good 4.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis : 136 Regency Park
+1-888-455-5160
136 Regency Park, O'fallon, IL 62269 +1-888-455-5160 ~35.69 miles southwest of Greenville
  • 2-star Suburban hotel
  • Comp. Breakfast
From£43
Average 3.0 /5 Reviews Call BookMore Details
Hilton Garden Inn St. Louis Shiloh / O'fallon Il in O'fallon
+1-888-965-8297
360 Regency Park, O'fallon, IL 62269 +1-888-965-8297 ~35.75 miles southwest of Greenville
  • 3 star Suburban hotel
  • Gym / Fitness Center Available
From£58
Average 3.0 /5 Reviews Call BookMore Details
Drury Inn St. Louis Collinsville - Collinsville
+1-888-906-6358
602 North Bluff Rd., Collinsville, IL 62234 +1-888-906-6358 ~35.78 miles west of Greenville
  • Three Star Suburban hotel
  • Hotel has 119 rooms
From£65
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America Select Suites - St. Louis - O' Fallon, IL : 154 Regency Park
+1-888-749-6785
154 Regency Park, O'fallon, IL 62269 +1-888-749-6785 ~35.78 miles southwest of Greenville
  • Cheap Highway property
  • 89 sleeping rooms in hotel
From£28
Average 3.0 /5 Latest Reviews Call BookMore Details
Towneplace Place Suites by Marriott St. Louis O Fallon Illinois - Ofallon
+1-888-878-9982
445 Regency Park Dr., Ofallon, IL 62269 +1-888-878-9982 ~35.78 miles southwest of Greenville
  • 3-star property
  • Access to gym on-site
From£65
Very good 4.0 /5 Hotel Reviews Call BookMore Details

Next: See My Greenville Hotels with Pricing

Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Dressed up Strip area."
Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025
"Quiet Area"
Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024
"Proximity to Carlyle"
Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024
"Greenville has some excellent museums!"
Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023
"Great Aquarium"
Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023
"College Campus"
Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023
"Loved It!"
Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022
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