Greenville Illinois Hotels & Motels

Find hotels in Greenville using the list and search tools below. Find cheap and discounted hotel/motel rates in or nearby Greenville, IL for your upcoming personal or group travel. Discover the most popular Greenville, Illinois hotel and motel rooms. Browse the Greenville area hotels to find the perfect lodging! Please use the provided map of the Greenville hotels.

The Greenville center is around the area of Edward A Utlaut Hospital and 17 miles west of Fayette County Museum.

Greenville Hotels, Motels & Accommodations

Super 8 by Wyndham Greenville in Greenville 1700 State Route 127, Greenville, IL 62246 Call
  • Low Cost Rural property
  • Free complimentary breakfast
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From£44
Average 3.0 /5 Review Score Call BookMore Details
SureStay by Best Western Greenville 1731 South State Route 127, Greenville, IL 62246 Call
  • Economical Highway hotel
  • Check in time: 04:00
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From£31
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites Greenville I-70 - Greenville 2265 South State Route 127, Greenville, IL 62246 Website Call
  • 2-star Rural hotel
  • 16 suites in hotel
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From£39
Very good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Vandalia Il in Vandalia 21 Mattes Ave., Vandalia, IL 62471 Call ~15.52 miles east of Greenville
  • 3-star Highway hotel
  • Check in time: 3:00 PM
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From£59
Average 3.0 /5 Read Reviews Call BookMore Details
Ramada by Wyndham Vandalia 2707 Veterans Ave., Vandalia, IL 62471 Call ~15.77 miles east of Greenville
  • Cheap hotel
  • Check-in: 11:00 AM
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From£44
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Americas Best Value Inn Vandalia : 1500 North 6th St. 1500 North 6th St., Vandalia, IL 62471 Call ~17.45 miles east of Greenville
  • Low priced Lake hotel
  • 2 floors in hotel
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From£37
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Quality Inn & Suites Vandalia near I-70 and Hwy 51 - Vandalia 1920 North Kennedy Blvd., Vandalia, IL 62471 Website Call ~17.57 miles east of Greenville
  • Inexpensive Highway property
  • 8 suites in hotel
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From£44
Very good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Vandalia near I-70 and Hwy 51 1920 Kennedy Blvd., Vandalia, IL 62471 Call ~17.59 miles east of Greenville
  • 2 star Rural property
  • Hotel has an eco-friendly policy Read more
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From£42
Very good 4.5 /5 Review Score Call BookMore Details
Seasons Inn & Suites Highland 20 Central Blvd., Highland, IL 62249 Call ~17.74 miles southwest of Greenville
  • 2 star hotel
  • Fitness + Health Center
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From£48
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Mariner's Village Resort & Inn - Carlyle 1 Resort Dr., Carlyle, IL 62231 Call ~18.34 miles south of Greenville
  • Cheap Lake property
  • Check in: 15:00
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From£44
Very good 4.0 /5 Latest Reviews Call BookMore Details
Centerstone Inn & Suites : 1371 William Rd. 1371 William Rd., Carlyle, IL 62231 Call ~18.46 miles south of Greenville
  • Inexpensive property
  • 2 floors in hotel
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From£44
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Super 8 by Wyndham Staunton 1527 Herman Rd., Staunton, IL 62088 Call ~21.09 miles west of Greenville
  • 2-star hotel
  • 2 floors in property
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From£37
Very good 4.0 /5 Latest Reviews Call BookMore Details
Innkeeper Motel in Hamel 401 East State St., Hamel, IL 62046 Call ~23.07 miles west of Greenville
  • Affordable Lake property
  • Check-in: 2:00 PM
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From£59
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Americas Best Value Inn Litchfield 224 North Ohren Lane, Litchfield, IL 62056 Call ~24.10 miles northwest of Greenville
  • Economy hotel
  • Free complimentary breakfast
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From£44
Poor 2.0 /5 Recent Reviews Call BookMore Details
Motel 6 Litchfield, IL 211 Ohren Ln, Litchfield, IL 62056 Call ~24.16 miles northwest of Greenville
  • Two-star Highway property
  • Check-in time: 11:00 AM
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From£44
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Baymont by Wyndham Litchfield in Litchfield 1405 West Hudson Dr., Litchfield, IL 62056 Call ~24.16 miles northwest of Greenville
  • Economical Highway hotel
  • Complimentary breakfast is offered
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From£44
Very good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn Litchfield Route 66 : 1010 East Columbian Blvd. North 1010 East Columbian Blvd. North, Litchfield, IL 62056 Website Call ~24.37 miles northwest of Greenville
  • Cheap Downtown property
  • Check-in time: 3:00 PM
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From£52
Very good 4.5 /5 Recent Reviews Call BookMore Details
Hampton Inn Litchfield 11 Thunderbird Cir, Litchfield, IL 62056 Call ~24.48 miles northwest of Greenville
  • Midscale Highway property
  • Check-in time: 3:00pm
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From£59
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Holiday Inn Express & Suites Litchfield West by IHG 4 Thunderbird Circle, Litchfield, IL 62056 Call ~24.49 miles northwest of Greenville
  • Three Star Rural hotel
  • Free breakfast
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From£59
Very good 4.0 /5 Review Score Call BookMore Details
Best Western Plus Centralia Hotel & Suites in Centralia 8145 Jolliff Bridge Rd., Centralia, IL 62801 Call ~28.09 miles southeast of Greenville
  • 3-star property
  • Hotel has 4 floors
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From£58
Very good 4.0 /5 Review Score Call BookMore Details
Americas Best Value Inn - Centralia 200 East Noleman, Centralia, IL 62801 Call ~29.09 miles southeast of Greenville
  • Economy property
  • 57 rooms in property
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From£44
Very good 4.0 /5 Latest Reviews Call BookMore Details
Motel 6 Troy Il - Troy 909 Edwardsville Rd., Troy, IL 62294 Call ~29.31 miles west of Greenville
  • Economy property
  • Check-in: 15:00
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From£37
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Quality Inn & Suites Salem near I-57 in Salem 1800 West Main St., Salem, IL 62881 Website Call ~29.38 miles southeast of Greenville
  • Cheap Rural property
  • Complimentary breakfast is offered
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From£51
Very good 4.0 /5 Guest Reviews Call BookMore Details
Best Western Troy Hotel 2020 Formosa Rd., Troy, IL 62294 Call ~29.44 miles west of Greenville
  • Affordable Rural hotel
  • Free breakfast available
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From£44
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Holiday Inn Express Troy by IHG 2011 Formosa Rd., Troy, IL 62294 Call ~29.51 miles west of Greenville
  • 3-star Highway property
  • Hotel has an eco-friendly policy Read more
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From£62
Very good 4.5 /5 Guest Reviews Call BookMore Details
Red Roof Inn St Louis - Troy, IL in Troy 2030 Formosa Rd., Troy, IL 62294 Call ~29.55 miles west of Greenville
  • Low Cost property
  • 3 floors in hotel
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From£39
Very good 4.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Salem, Illinois 1812 West Main St., Salem, IL 62881 Call ~29.55 miles southeast of Greenville
  • Inexpensive property
  • Check-in: 3:00pm
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From£35
Very good 4.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Troy IL/St. Louis Area : 910 Edwardsville Rd. 910 Edwardsville Rd., Troy, IL 62294 Call ~29.60 miles west of Greenville
  • Low priced Highway hotel
  • Comp. Breakfast
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From£47
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Super 8 by Wyndham Salem 118 Woods Ln, Salem, IL 62881 Call ~29.63 miles southeast of Greenville
  • Low-priced Highway property
  • Check in: 3:00pm
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From£44
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Magnuson Grand Hotel And Conference Center 19067 West Frontage Rd., Raymond, IL 62560 Call ~29.70 miles northwest of Greenville
  • Three Star Rural property
  • 2 floors in hotel
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From£36
Very good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Salem by IHG 102 Holiday Lane, Salem, IL 62881 Call ~29.89 miles southeast of Greenville
  • 3-star Highway hotel
  • Hotel has an eco-friendly policy See more
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From£65
Excellent 5.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Edwardsville by IHG : 1000 Plummer Dr. 1000 Plummer Dr., Edwardsville, IL 62025 Call ~31.59 miles west of Greenville
  • Midscale Suburban property
  • Fitness / Gym is on-site
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From£70
Very good 4.0 /5 Review Score Call BookMore Details
Country Hearth Inn & Suites Edwardsville St. Louis in Edwardsville 1013 Plummer Dr., Edwardsville, IL 62025 Call ~31.66 miles west of Greenville
  • Affordable Rural hotel
  • Gym / Fitness Center Available
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From£50
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Towneplace Suites by Marriott St. Louis Edwardsville Il 6101 Center Grove Rd., Edwardsville, IL 62025 Call ~31.67 miles west of Greenville
  • Midscale Suburban property
  • 91 sleeping rooms in hotel
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From£67
Very good 4.0 /5 Guest Reviews Call BookMore Details
Best Western Plus MidAmerica Hotel in Mascoutah 9730 Hayden Dr., Mascoutah, IL 62258 Call ~32.05 miles southwest of Greenville
  • Midscale Suburban hotel
  • Complimentary breakfast is offered
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From£51
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Okawville - Okawville 812 North Henhouse Rd., Okawville, IL 62271 Call ~32.28 miles south of Greenville
  • 2 star Rural property
  • Hotel has 2 suites
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From£47
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Super 8 by Wyndham Okawville 812 North Hen House Rd., Okawville, IL 62271 Call ~32.28 miles south of Greenville
  • Two-star property
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From£44
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham O'fallon 1100 Eastgate Dr., Ofallon, IL 62269 Call ~33.41 miles southwest of Greenville
  • Economy Suburban property
  • Hotel has an eco-friendly policy See more
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From£29
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Comfort Inn Edwardsville - St. Louis in Edwardsville 3080 South State Rte 157, Edwardsville, IL 62025 Website Call ~33.44 miles west of Greenville
  • Cheap Highway property
  • 71 rooms in hotel
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From£44
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Comfort Inn Edwardsville : 3080 Il 157 3080 Il 157, Edwardsville, IL 62025 Call ~33.44 miles west of Greenville
  • Affordable Highway property
  • Free complimentary breakfast
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From£59
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Hampton Inn & Suites St. Louis Edwardsville - Glen Carbon 5723 Heritage Crossing Dr., Glen Carbon, IL 62034 Call ~33.74 miles west of Greenville
  • Three Star Suburban hotel
  • Complimentary breakfast is offered
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From£73
Very good 4.0 /5 Recent Reviews Call BookMore Details
Best Western U. S. Inn 11640 State Route 127, Nashville, IL 62263 Call ~35.22 miles south of Greenville
  • Affordable Highway property
  • 2 floors in property
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From£47
Very good 4.0 /5 Recent Reviews Call BookMore Details
Sleep Inn O Fallon Il 140 Venita Dr., O'fallon, IL 62269 Call ~35.35 miles southwest of Greenville
  • Affordable Suburban property
  • Comp. Breakfast
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From£59
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Holiday Inn Express & Suites O'fallon / Shiloh An Ihg Hotel 3396 Green Mount Crossing, Shiloh, IL 62269 Call ~35.48 miles southwest of Greenville
  • Affordable Highway property
  • 3 floors in property
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From£73
Very good 4.0 /5 Reviews Call BookMore Details
Comfort Inn & Suites Ofallon St. Louis Area in O'fallon 116 Regency Park, O'fallon, IL 62269 Call ~35.51 miles southwest of Greenville
  • Economy Suburban property
  • Check in: 3:00 PM
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From£44
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Hampton Inn O'fallon Il 430 Regency Park, O'fallon, IL 62269 Call ~35.57 miles southwest of Greenville
  • Three Star Suburban property
  • 100 rooms in property
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From£59
Very good 4.0 /5 Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham O'fallon Il St. Louis 136 Regency Park, O'fallon, IL 62269 Call ~35.59 miles southwest of Greenville
  • 2 star Suburban hotel
  • 2 floors in property
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From£44
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Hilton Garden Inn St. Louis Shiloh / O'fallon Il 360 Regency Park, O'fallon, IL 62269 Call ~35.65 miles southwest of Greenville
  • Midscale Suburban property
  • Hotel has 20 suites
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From£59
Average 3.0 /5 Guest Reviews Call BookMore Details
Extended Stay America Select Suites - St. Louis - O' Fallon, IL 154 Regency Park, O'fallon, IL 62269 Call ~35.68 miles southwest of Greenville
  • Inexpensive Highway property
  • 89 rooms in property
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From£29
Average 3.0 /5 Reviews Call BookMore Details
Drury Inn St. Louis Collinsville 602 North Bluff Rd., Collinsville, IL 62234 Call ~35.68 miles west of Greenville
  • 3-star Suburban property
  • 119 rooms in property
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From£67
Very good 4.0 /5 Recent Reviews Call BookMore Details

Next: See My Greenville Hotels with Pricing

Verified reviews of the city of Greenville

Below are reviews of the city of Greenville, IL from an actual visitor's perspective.

"Quiet town"
Score 4.0 / 5

Quiet town and my Son plays Basketball for Greenville university.

Newton A., from 26-Feb-2026
"Great Diner!"
Score 4.0 / 5

Vicky's Cafe was awesome!! Very helpful and polite staff! Clean diner with great food!

Amy S., from 24-Aug-2025
"Dressed up Strip area."
Score 4.0 / 5

They have dressed up the hotel strip area since our last visit.

Phillip D., from 22-Jun-2025
"Quiet Area"
Score 5.0 / 5

Quietness compared to the big city.

Marien C., from 09-Jul-2024
"Proximity to Carlyle"
Score 4.0 / 5

I was visiting family in Carlyle and this is the best location to stay.

Robin S., from 09-Jul-2024
"Greenville has some excellent museums!"
Score 5.0 / 5

Greenville has some excellent museums!

Hh K., from 17-Sep-2023
"Great Aquarium"
Score 4.0 / 5

I went to the aquarium which I thought was great!

Augustino P., from 26-Jun-2023
"College Campus"
Score 4.0 / 5

Visited the college campus.

Kelly M., from 13-Mar-2023
"Loved It!"
Score 5.0 / 5

Loved it all!

Tom W., from 28-Dec-2022
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