Hotels in 14221 - Buffalo NY

Only hotels in 14221 zip code are listed below. Search for cheap and discount hotel rates in Buffalo, NY for your upcoming leisure or conference / group travel. We list the best 14221 hotels and motels so you can review the Buffalo hotel list below to find the perfect lodging. Hotels in Erie county and area code 716 are also listed.

Star Rating
Hotel Name
Price Range (USD) to
Amenities
+ More

14221 Hotels/Motels & Accommodations

La Quinta Inn by Wyndham Buffalo Airport in Williamsville 6619 Transit Rd., Williamsville, NY 14221
Call Us
  • Economy Airport hotel
  • 2 floors in hotel
More Photos Exterior of La Quinta Inn by Wyndham Buffalo Airport
From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 14221" Get Alexa Skill →
Hawthorn Suites by Wyndham Williamsville Buffalo Airport 8005 Sheridan Dr., Williamsville, IN 14221
Call Us
  • Midscale Airport hotel
  • Airport shuttle provided
More Photos Photo of Hawthorn Suites by Wyndham Williamsville Buffalo Airport
From$80
Average 3.0 /5 Reviews Call BookMore Details
Springhill Suites Buffalo Airport 6647 Transit Rd., Buffalo, NY 14221
Call Us
  • 3-star Suburban property
  • Hotel has 2 suites
More Photos Exterior of Springhill Suites Buffalo Airport
From$79
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Fairbridge Inn Express Buffalo Airport Williamsville 7200 Transit Rd., Williamsville, NY 14221
Call Us
  • Economical Airport hotel
  • Hotel has 2 floors
More Photos Photo of Fairbridge Inn Express Buffalo Airport Williamsville
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Buffalo-Williamsville 5455 Main St., Williamsville, NY 14221
Call Us
  • 3 star Suburban hotel
  • Check in: 3:00 PM
More Photos Exterior of Hampton Inn Buffalo-Williamsville
From$95
Very Good 4.0 /5 Guest Reviews Call BookMore Details
The Mosey Hotel a Tapestry Collection by Hilton : 5195 Main St. 5195 Main St., Buffalo, NY 14221
Call Us
  • High-end Suburban property
  • Hotel has a green policy See policy
More Photos Photo of The Mosey Hotel a Tapestry Collection by Hilton
From$69
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Tru by Hilton Williamsville Buffalo Airport : 48 Freeman Rd. Building A 48 Freeman Rd. Building A, Williamsville, NY 14221
Call Us
  • 3 star Airport hotel
  • Airport shuttle available
More Photos Photo of Tru by Hilton Williamsville Buffalo Airport
From$75
Average 3.0 /5 Read Reviews Call BookMore Details
Motel 6 Buffalo Ny Airport Williamsville : 52 Freeman Rd. 52 Freeman Rd., Buffalo, NY 14221
Call Us
  • 2 star Airport hotel
  • Check-in time: 15:00
More Photos Exterior of Motel 6 Buffalo Ny Airport Williamsville
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Best Western Buffalo Inn & Suites in Buffalo 50 Freeman Rd., Buffalo, NY 14221
Call Us
  • Midscale Airport property
  • 2 floors in hotel
More Photos Image of Best Western Buffalo Inn & Suites
From$72
Average 3.0 /5 Latest Reviews Call BookMore Details
Garden Place Hotel 6615 Transit Rd., Williamsville, NY 14221
Call Us
  • Affordable Airport hotel
  • Check in: 3:00 PM
More Photos Exterior of Garden Place Hotel
From$81
Average 3.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Buffalo Amherst/University 4100 Sheridan Dr., Buffalo, NY 14221
Call Us
  • Midscale Suburban property
  • Fitness center on property
More Photos Exterior of Courtyard by Marriott Buffalo Amherst/University
From$119
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Residence Inn Buffalo Amherst - Amherst 100 Maple Rd., Amherst, NY 14221
Call Us
  • Three Star Suburban hotel
  • Hotel has 112 suites
More Photos Photo of Residence Inn Buffalo Amherst
From$79
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn Amherst / Buffalo - Buffalo 1601 Amherst Manor Dr., Buffalo, NY 14221
Call Us
  • Mid-scale Suburban property
  • Check in: 3PM
More Photos Photo of Hampton Inn Amherst / Buffalo
From$80
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
More Homes & Apts at Booking.com

Book online or call +1-800-219-2797

Booking for Homes and Apartments
Go to BookingGo to Booking
Buffalo Marriott Niagara : 1340 Millersport Highway 1340 Millersport Highway, Amherst, NY 14221
Call Us
  • 4-star Suburban property
  • Hotel has 356 rooms
More Photos Photo of Buffalo Marriott Niagara
From$125
Average 3.0 /5 Review Score Call BookMore Details
Hyatt Place Buffalo/Amherst - Amherst 5020 Main St., Amherst, NY 14226
Call Us
~2.50 miles southwest of 14221
  • 3 star Suburban property
  • Shuttle from airport available
More Photos Exterior of Hyatt Place Buffalo/Amherst
From$95
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 14221" Get Alexa Skill →
Jazzboline - Amherst 5010 Main St., Amherst, NY 14226
Call Us
~2.68 miles southwest of 14221
  • Four star property
More Photos hotel room
From$75
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Red Roof Inn Buffalo - Niagara Airport - Bowmansville 146 Maple Dr., Bowmansville, NY 14026
Call Us
~2.68 miles southeast of 14221
  • Low-priced Airport property
  • Check-in: 12:00 PM
More Photos Image of Red Roof Inn Buffalo - Niagara Airport
From$82
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Reikart House, Buffalo, a Tribute Portfolio Hotel : 5000 Main St. 5000 Main St., Amherst, NY 14226
Call Us
~2.70 miles southwest of 14221
  • Expensive Suburban hotel
  • Comp. Breakfast
More Photos Exterior of Reikart House, Buffalo, a Tribute Portfolio Hotel
From$129
Very Good 4.0 /5 Read Reviews Call BookMore Details
Sleep Inn Buffalo Airport in Cheektowaga 100 Holtz Dr., Cheektowaga, NY 14225
Call Us
~3.00 miles south of 14221
  • Low priced Airport hotel
  • Hotel has an eco-friendly policy Learn more
More Photos Image of Sleep Inn Buffalo Airport
From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Inn at Buffalo Airport : 4630 Genesee St. 4630 Genesee St., Cheektowaga, NY 14225
Call Us
~3.13 miles south of 14221
  • Inexpensive Airport hotel
  • 4 floors in property
More Photos Photo of Inn at Buffalo Airport
From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Buffalo Airport Hotel - Cheektowaga 4600 Genesee St., Cheektowaga, NY 14225
Call Us
~3.15 miles south of 14221
  • Affordable Airport hotel
  • Check in: 4:00 PM
More Photos Photo of Buffalo Airport Hotel
From$49
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites Buffalo Airport in Buffalo 4345 Genesee St., Buffalo, NY 14225
Call Us
~3.32 miles south of 14221
  • Affordable Suburban hotel
  • Shuttle to airport available
More Photos Exterior of Comfort Inn & Suites Buffalo Airport
From$99
Average 3.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Buffalo Airport 4271 Genesee St., Buffalo, NY 14225
Call Us
~3.34 miles south of 14221
  • Three Star Airport hotel
  • Airport shuttle available
More Photos Photo of Fairfield Inn & Suites by Marriott Buffalo Airport
From$107
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard Buffalo Airport 4243 Genesee St., Cheektowaga, NY 14225
Call Us
~3.40 miles south of 14221
  • Affordable Airport property
  • Check in: 3:00 PM
More Photos Exterior of Courtyard Buffalo Airport
From$97
Very Good 4.0 /5 Read Reviews Call BookMore Details
Comfort Inn University : 1 Flint Rd. 1 Flint Rd., Amherst, NY 14226
Call Us
~3.42 miles west of 14221
  • Two star Suburban property
  • Check in time: 3pm
More Photos Exterior of Comfort Inn University
From$55
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn Buffalo Airport 4201 Genesee St., Buffalo, NY 14225
Call Us
~3.45 miles south of 14221
  • 3-star Airport hotel
  • Shuttle from airport available
More Photos Image of Hilton Garden Inn Buffalo Airport
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
DoubleTree by Hilton Hotel Buffalo - Amherst 10 Flint Rd., Amherst, NY 14226
Call Us
~3.46 miles west of 14221
  • High end Suburban hotel
  • Check in: 3:00pm
More Photos Photo of DoubleTree by Hilton Hotel Buffalo - Amherst
From$99
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn PLUS+ University at Buffalo - Amherst - Amherst 42 Flint Rd., Amherst, NY 14226
Call Us
~3.46 miles west of 14221
  • Cheap Suburban property
  • 108 sleeping rooms in hotel
More Photos Exterior of Red Roof Inn PLUS+ University at Buffalo - Amherst
From$52
Poor 2.0 /5 Latest Reviews Call BookMore Details
Towneplace Suites Buffalo Airport : 4265 Genesee St. 4265 Genesee St., Buffalo, NY 14225
Call Us
~3.48 miles south of 14221
  • 3-star Airport hotel
  • Hotel has an eco-friendly policy See more
More Photos Photo of Towneplace Suites Buffalo Airport
From$109
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Buffalo Inn Hospitality - Buffalo 4217 Genesee St., Buffalo, NY 14225
Call Us
~3.49 miles south of 14221
  • Cheap Airport hotel
  • Complimentary breakfast is offered
More Photos Image of Buffalo Inn Hospitality
From$80
Poor 2.0 /5 Review Score Call BookMore Details
Aloft Buffalo Airport - Cheektowaga 4219 Genesee St., Cheektowaga, NY 14225
Call Us
~3.54 miles south of 14221
  • 3 star Airport property
  • Fitness + Health Center
More Photos Exterior of Aloft Buffalo Airport
From$88
Average 3.0 /5 Reviews Call BookMore Details
Candlewood Suites Buffalo - Amherst by IHG in Amherst 20 Flint Rd., Amherst, NY 14226
Call Us
~3.54 miles west of 14221
  • Economy Suburban property
  • Fitness center on property
More Photos Exterior of Candlewood Suites Buffalo - Amherst by IHG
From$60
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Homewood Suites by Hilton Buffalo/Amherst 1138 Millersport Highway, Amherst, NY 14226
Call Us
~3.59 miles west of 14221
  • Mid-scale Suburban property
  • Check-in time: 3:00 PM
More Photos Photo of Homewood Suites by Hilton Buffalo/Amherst
From$118
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG 131 Buell Ave., Cheektowaga, NY 14225
Call Us
~3.67 miles south of 14221
  • 3-star Airport hotel
  • Hotel has 4 floors
More Photos Image of Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
From$79
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Clarence Inn - Clarence 9079 Main St., Clarence, NY 14032
Call Us
~3.72 miles east of 14221
  • 3-star Airport hotel
  • Hotel has 14 rooms
More Photos Image of Clarence Inn
From$48
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Extended Stay of America - Cheektowaga 901 Dick Rd., Cheektowaga, NY 14225
Call Us
~3.77 miles south of 14221
  • 3 star Airport property
  • Gym / Fitness Center Available
More Photos Photo of Extended Stay of America
From$80
Average 3.0 /5 Reviews Call BookMore Details
Motel 6 Amherst, NY - Buffalo in Amherst 4400 Maple Rd., Amherst, NY 14226
Call Us
~3.93 miles west of 14221
  • 2 star property
  • Hotel has 93 rooms
More Photos Image of Motel 6 Amherst, NY - Buffalo
From$60
Average 3.0 /5 Review Score Call BookMore Details
Homewood Suites by Hilton Buffalo Airport in Cheektowaga 760 Dick Rd., Cheektowaga, NY 14225
Call Us
~3.96 miles south of 14221
  • 3-star Airport hotel
  • Gym / Fitness Center Available
More Photos Photo of Homewood Suites by Hilton Buffalo Airport
From$104
Very Good 4.5 /5 Read Reviews Call BookMore Details
Staybridge Suites Buffalo Amherst in Amherst 1290 Sweet Home Rd., Amherst, NY 14228
Call Us
~4.02 miles west of 14221
  • 3 star Suburban hotel
  • Check-in time: 3:00 PM
More Photos Image of Staybridge Suites Buffalo Amherst
From$85
Very Good 4.5 /5 Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Buffalo Amherst/University - Amherst 3880 Rensch Rd. Amherst Ny 14228, Amherst, NY 14228
Call Us
~4.04 miles west of 14221
  • 3-star Suburban property
  • 4 floors in property
More Photos Photo of Fairfield Inn & Suites by Marriott Buffalo Amherst/University
From$54
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Village Haven Inn & Extended Stay 9370 Main St., Clarence, NY 14031
Call Us
~4.25 miles east of 14221
  • Low Cost property
  • 40 sleeping rooms in hotel
More Photos Photo of Village Haven Inn & Extended Stay
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
University Manor Inn : 3612 Main St. 3612 Main St., Buffalo, NY 14226
Call Us
~4.78 miles west of 14221
  • Two-star Downtown hotel
  • Check-in time: 1500
More Photos Exterior of University Manor Inn
From$40
Average 3.0 /5 Recent Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Buffalo Amherst : 145 Innkeepers Lane 145 Innkeepers Lane, Buffalo, NY 14228
Call Us
~4.96 miles west of 14221
  • 3 star Suburban hotel
  • Free complimentary breakfast
More Photos Photo of La Quinta Inn & Suites by Wyndham Buffalo Amherst
From$80
Average 3.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Tonawanda/Buffalo 1120 Niagarafalls Blvd., Tonawanda, NY 14150
Call Us
~4.96 miles west of 14221
  • 2 star Suburban hotel
  • Check in: 3:00 PM
More Photos Exterior of Days Inn by Wyndham Tonawanda/Buffalo
From$60
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Buffalo Amherst 125 Inn Keepers Ln., Amherst, NY 14228
Call Us
~5.02 miles west of 14221
  • Low priced hotel
  • 119 suites in property
More Photos Photo of Extended Stay America Suites Buffalo Amherst
From$52
Average 3.0 /5 Reviews Call BookMore Details
Home2 Suites by Hilton Amherst Buffalo : 3820 Ridge Lea Rd. 3820 Ridge Lea Rd., Amherst, NY 14228
Call Us
~5.07 miles west of 14221
  • Mid-scale Suburban property
  • Gym is available on property
More Photos Photo of Home2 Suites by Hilton Amherst Buffalo
From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Sleep Inn Amherst - Buffalo North near University - Amherst 75 Inn Keepers Lane, Amherst, NY 14228
Call Us
~5.16 miles west of 14221
  • Economical Suburban property
  • 92 sleeping rooms in hotel
More Photos Image of Sleep Inn Amherst - Buffalo North near University
From$75
Very Good 4.0 /5 Read Reviews Call BookMore Details
Baymont by Wyndham Buffalo - Buffalo 3475 Union Rd., Buffalo, NY 14225
Call Us
~5.17 miles south of 14221
  • Two-star hotel
  • 56 rooms in property
More Photos Exterior of Baymont by Wyndham Buffalo
From$75
Average 3.0 /5 Latest Reviews Call BookMore Details
M Hotel Buffalo 2040 Walden Ave., Buffalo, NY 14225
Call Us
~5.21 miles south of 14221
  • Low Cost Airport property
  • 8 floors in hotel
More Photos Photo of M Hotel Buffalo
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Amherst Inn & Suites in Amherst 1951 Niagara Falls Blvd., Amherst, NY 14228
Call Us
~5.22 miles west of 14221
  • Economy Downtown hotel
  • Check in time: 11:00
More Photos Exterior of Amherst Inn & Suites
From$60
Average 3.5 /5 Guest Reviews Call BookMore Details

Next: Show All Available 14221 Hotels with Pricing

Graph of Williamsville, NY Hotel Prices for Next 20 Days

Rates shown are nightly rates before taxes and do not necessarily reflect all Williamsville, NY discounts available. The chart reflects the cheapest Williamsville hotel for each day and each star rating category.

FAQs about hotels near 14221

What are the most favored hotels near 14221?

Fairfield Inn & Suites by Marriott Buffalo Amherst, Candlewood Suites Buffalo - Amherst by IHG and Homewood Suites by Hilton Buffalo Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels near 14221?

The Mosey Hotel a Tapestry Collection by Hilton, Buffalo Marriott Niagara and Jazzboline are the top 3 luxury hotels near 14221.

What hotels are closest to the area of 14221?

La Quinta Inn by Wyndham Buffalo Airport, Hawthorn Suites by Wyndham Williamsville Buffalo Airport, and Springhill Suites Buffalo Airport are the properties closest to 14221.

How much does a cheap hotel near 14221 cost per night?

In the last year, a 2 star hotel near 14221 can be as cheap as $74.66 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 14221 cost per night?

In the last year, the average 3 star hotel near 14221 has been $97.89 per night. (based on HotelPlanner prices)

How much does a high-end hotel near 14221 cost?

In the last year, the average 4 star hotel near 14221 has been $140.50 per night. (based on HotelPlanner prices)

What are the best independent hotels near 14221?

Jazzboline, Inn at Buffalo Airport and Clarence Inn are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 14221?

Fairfield Inn & Suites by Marriott Buffalo Amherst, Springhill Suites Buffalo Airport and Courtyard by Marriott Buffalo Amherst are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 14221?

Sleep Inn Buffalo Airport, Comfort Inn University and Sleep Inn Amherst - Buffalo North near University are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 14221?

Candlewood Suites Buffalo - Amherst by IHG, Staybridge Suites Buffalo Amherst and Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Back to Top