Hotels in 14221 - Buffalo NY

Only hotels in 14221 zip code are listed below. Search for cheap and discount hotel rates in Buffalo, NY for your upcoming leisure or conference / group travel. We list the best 14221 hotels and motels so you can review the Buffalo hotel list below to find the perfect lodging. Hotels in Erie county and area code 716 are also listed.

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14221 Hotels/Accommodations

La Quinta Inn by Wyndham Buffalo Airport in Williamsville
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
6619 Transit Rd., Williamsville, NY 14221
  • 2 star Airport property
  • Gym is available on property
More Photos Image of La Quinta Inn by Wyndham Buffalo Airport
From$79
Average 3.0 /5 Hotel Reviews Call BookMore Details
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Hawthorn Suites by Wyndham Williamsville Buffalo Airport : 8005 Sheridan Dr.
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
8005 Sheridan Dr., Williamsville, IN 14221
  • Affordable Airport property
  • Check-in: 4:00PM
More Photos Photo of Hawthorn Suites by Wyndham Williamsville Buffalo Airport
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Springhill Suites Buffalo Airport : 6647 Transit Rd.
+1-800-716-8490

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New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
6647 Transit Rd., Buffalo, NY 14221
  • Three Star Suburban hotel
  • Check in time: 3:00PM
More Photos Exterior of Springhill Suites Buffalo Airport
From$79
Very Good 4.0 /5 Read Reviews Call BookMore Details
Fairbridge Inn Express Buffalo Airport Williamsville in Williamsville
+1-800-805-5223

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New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
7200 Transit Rd., Williamsville, NY 14221
  • 2-star Airport property
  • 2 floors in hotel
More Photos Exterior of Fairbridge Inn Express Buffalo Airport Williamsville
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Buffalo-Williamsville : 5455 Main St.
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
5455 Main St., Williamsville, NY 14221
  • 3-star Suburban hotel
  • Fitness + Health Center
More Photos Image of Hampton Inn Buffalo-Williamsville
From$95
Very Good 4.0 /5 Latest Reviews Call BookMore Details
The Mosey Hotel a Tapestry Collection by Hilton : 5195 Main St.
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
5195 Main St., Buffalo, NY 14221
  • High end Suburban property
  • 6 floors in hotel
More Photos Image of The Mosey Hotel a Tapestry Collection by Hilton
From$69
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Tru by Hilton Williamsville Buffalo Airport : 48 Freeman Rd. Building A
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
48 Freeman Rd. Building A, Williamsville, NY 14221
  • 3 star Airport hotel
  • Fitness center on property
More Photos Image of Tru by Hilton Williamsville Buffalo Airport
From$75
Average 3.0 /5 Reviews Call BookMore Details
Motel 6 Buffalo Ny Airport Williamsville
+1-888-311-4278

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New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
52 Freeman Rd., Buffalo, NY 14221
  • Cheap Airport hotel
  • Hotel has 130 rooms
More Photos Exterior of Motel 6 Buffalo Ny Airport Williamsville
From$60
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Best Western Buffalo Inn & Suites
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
50 Freeman Rd., Buffalo, NY 14221
  • 3 star Airport hotel
  • Complimentary breakfast is offered
More Photos Image of Best Western Buffalo Inn & Suites
From$73
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Garden Place Hotel
+1-888-734-9421

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New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
6615 Transit Rd., Williamsville, NY 14221
  • 3 star Airport hotel
  • Check-in time: 3:00 PM
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From$81
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Courtyard by Marriott Buffalo Amherst/University : 4100 Sheridan Dr.
+1-888-841-5292

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New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
4100 Sheridan Dr., Buffalo, NY 14221
  • Affordable Suburban property
  • Check-in time: 3:00pm
More Photos Image of Courtyard by Marriott Buffalo Amherst/University
From$119
Very Good 4.0 /5 Review Score Call BookMore Details
Residence Inn Buffalo Amherst : 100 Maple Rd.
+1-888-455-5160

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100 Maple Rd., Amherst, NY 14221
  • Three Star Suburban property
  • Has environment-friendly policy See policy
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From$79
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Hampton Inn Amherst / Buffalo - Buffalo
+1-888-965-8297

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New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1601 Amherst Manor Dr., Buffalo, NY 14221
  • Three Star Suburban hotel
  • 4 floors in property
More Photos Photo of Hampton Inn Amherst / Buffalo
From$80
Very Good 4.0 /5 Reviews Call BookMore Details
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Buffalo Marriott Niagara
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1340 Millersport Highway, Amherst, NY 14221
  • High end Suburban property
  • Check-in: 4: 00 pm
More Photos Image of Buffalo Marriott Niagara
From$125
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Hyatt Place Buffalo/Amherst - Amherst
+1-888-749-6785

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New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
5020 Main St., Amherst, NY 14226 ~2.50 miles southwest of 14221
  • Three Star Suburban property
  • Hotel has 6 floors
More Photos Exterior of Hyatt Place Buffalo/Amherst
From$95
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Jazzboline : 5010 Main St.
+1-888-878-9982

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New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
5010 Main St., Amherst, NY 14226 ~2.68 miles southwest of 14221
  • Four-star hotel
More Photos hotel room
From$75
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Red Roof Inn Buffalo - Niagara Airport in Bowmansville
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
146 Maple Dr., Bowmansville, NY 14026 ~2.68 miles southeast of 14221
  • Low priced Airport hotel
  • Hotel has 109 rooms
More Photos Photo of Red Roof Inn Buffalo - Niagara Airport
From$82
Very Good 4.0 /5 Reviews Call BookMore Details
Reikart House, Buffalo, a Tribute Portfolio Hotel
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
5000 Main St., Amherst, NY 14226 ~2.70 miles southwest of 14221
  • 4-star Suburban property
  • Complimentary breakfast is offered
More Photos Photo of Reikart House, Buffalo, a Tribute Portfolio Hotel
From$129
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Sleep Inn Buffalo Airport
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
100 Holtz Dr., Cheektowaga, NY 14225 ~3.00 miles south of 14221
  • 2-star Airport property
  • Hotel has an eco-friendly policy Learn more
More Photos Photo of Sleep Inn Buffalo Airport
From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Inn at Buffalo Airport in Cheektowaga
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
4630 Genesee St., Cheektowaga, NY 14225 ~3.13 miles south of 14221
  • 2-star Airport hotel
  • Hotel has 4 floors
More Photos Image of Inn at Buffalo Airport
From$60
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Buffalo Airport Hotel
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
4600 Genesee St., Cheektowaga, NY 14225 ~3.15 miles south of 14221
  • 3-star Airport hotel
  • Check-in time: 4:00 PM
More Photos Image of Buffalo Airport Hotel
From$49
Average 3.0 /5 Review Score Call BookMore Details
Comfort Inn & Suites Buffalo Airport
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
4345 Genesee St., Buffalo, NY 14225 ~3.32 miles south of 14221
  • Affordable Suburban hotel
  • Free complimentary breakfast
More Photos Image of Comfort Inn & Suites Buffalo Airport
From$99
Average 3.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Buffalo Airport - Buffalo
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
4271 Genesee St., Buffalo, NY 14225 ~3.34 miles south of 14221
  • 3-star Airport property
  • Access to gym on-site
More Photos Exterior of Fairfield Inn & Suites by Marriott Buffalo Airport
From$107
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard Buffalo Airport - Cheektowaga
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
4243 Genesee St., Cheektowaga, NY 14225 ~3.40 miles south of 14221
  • Three Star Airport property
  • 5 suites in hotel
More Photos Image of Courtyard Buffalo Airport
From$97
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn University
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1 Flint Rd., Amherst, NY 14226 ~3.42 miles west of 14221
  • Low priced Suburban property
  • Check in: 3pm
More Photos Photo of Comfort Inn University
From$55
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hilton Garden Inn Buffalo Airport - Buffalo
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
4201 Genesee St., Buffalo, NY 14225 ~3.45 miles south of 14221
  • Mid-scale Airport property
  • Airport shuttle available
More Photos Exterior of Hilton Garden Inn Buffalo Airport
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
DoubleTree by Hilton Hotel Buffalo - Amherst - Amherst
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
10 Flint Rd., Amherst, NY 14226 ~3.46 miles west of 14221
  • High-end Suburban hotel
  • 196 rooms in hotel
More Photos Exterior of DoubleTree by Hilton Hotel Buffalo - Amherst
From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Red Roof Inn PLUS+ University at Buffalo - Amherst
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
42 Flint Rd., Amherst, NY 14226 ~3.46 miles west of 14221
  • Cheap Suburban property
  • Hotel has 108 rooms
More Photos Photo of Red Roof Inn PLUS+ University at Buffalo - Amherst
From$52
Poor 2.0 /5 Latest Reviews Call BookMore Details
Towneplace Suites Buffalo Airport
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
4265 Genesee St., Buffalo, NY 14225 ~3.48 miles south of 14221
  • 3 star Airport hotel
  • Check-in: 3:00 PM
More Photos Exterior of Towneplace Suites Buffalo Airport
From$109
Very Good 4.0 /5 Review Score Call BookMore Details
Quality Inn Buffalo Airport in Buffalo
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
4217 Genesee St., Buffalo, NY 14225 Website ~3.49 miles south of 14221
  • Low priced Airport hotel
  • 2 floors in hotel
More Photos Exterior of Quality Inn Buffalo Airport
From$80
Poor 2.0 /5 Review Score Call BookMore Details
Aloft Buffalo Airport
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
4219 Genesee St., Cheektowaga, NY 14225 ~3.54 miles south of 14221
  • 3-star Airport property
  • Check-in: 3:00 PM
More Photos Photo of Aloft Buffalo Airport
From$88
Average 3.0 /5 Hotel Reviews Call BookMore Details
Candlewood Suites Buffalo - Amherst by IHG : 20 Flint Rd.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
20 Flint Rd., Amherst, NY 14226 ~3.54 miles west of 14221
  • 2-star Suburban property
  • Hotel has 76 suites
More Photos Exterior of Candlewood Suites Buffalo - Amherst by IHG
From$60
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Homewood Suites by Hilton Buffalo/Amherst
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1138 Millersport Highway, Amherst, NY 14226 ~3.59 miles west of 14221
  • Three Star Suburban property
  • Hotel has a green policy See policy
More Photos Image of Homewood Suites by Hilton Buffalo/Amherst
From$118
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG - Cheektowaga
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
131 Buell Ave., Cheektowaga, NY 14225 ~3.67 miles south of 14221
  • 3 star Airport hotel
  • 110 sleeping rooms in hotel
More Photos Image of Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
From$79
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Clarence Inn
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
9079 Main St., Clarence, NY 14032 ~3.72 miles east of 14221
  • 3-star Airport property
  • Hotel has 14 rooms
More Photos Image of Clarence Inn
From$48
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Extended Stay of America
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
901 Dick Rd., Cheektowaga, NY 14225 ~3.77 miles south of 14221
  • Mid-scale Airport hotel
  • 2 meeting rooms in hotel
More Photos Exterior of Extended Stay of America
From$80
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 Amherst, NY - Buffalo
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
4400 Maple Rd., Amherst, NY 14226 ~3.93 miles west of 14221
  • 2-star hotel
  • Check-in: 14:00
More Photos Image of Motel 6 Amherst, NY - Buffalo
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Homewood Suites by Hilton Buffalo Airport - Cheektowaga
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
760 Dick Rd., Cheektowaga, NY 14225 ~3.96 miles south of 14221
  • 3-star Airport property
  • 77 sleeping rooms in hotel
More Photos Image of Homewood Suites by Hilton Buffalo Airport
From$104
Very Good 4.5 /5 Read Reviews Call BookMore Details
Staybridge Suites Buffalo Amherst in Amherst
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1290 Sweet Home Rd., Amherst, NY 14228 ~4.02 miles west of 14221
  • Affordable Suburban property
  • 102 sleeping rooms in hotel
More Photos Exterior of Staybridge Suites Buffalo Amherst
From$85
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Buffalo Amherst/University
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
3880 Rensch Rd. Amherst Ny 14228, Amherst, NY 14228 ~4.04 miles west of 14221
  • Midscale Suburban property
  • Hotel has 4 floors
More Photos Photo of Fairfield Inn & Suites by Marriott Buffalo Amherst/University
From$54
Excellent 5.0 /5 Reviews Call BookMore Details
Village Haven Inn & Extended Stay
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
9370 Main St., Clarence, NY 14031 ~4.25 miles east of 14221
  • Economy property
More Photos Photo of Village Haven Inn & Extended Stay
From$60
Average 3.0 /5 Reviews Call BookMore Details
University Manor Inn : 3612 Main St.
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
3612 Main St., Buffalo, NY 14226 ~4.78 miles west of 14221
  • Low-priced Downtown property
  • 2 floors in property
More Photos Photo of University Manor Inn
From$40
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La Quinta Inn & Suites by Wyndham Buffalo Amherst : 145 Innkeepers Lane
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
145 Innkeepers Lane, Buffalo, NY 14228 ~4.96 miles west of 14221
  • Mid-scale Suburban hotel
  • Free comp. breakfast
More Photos Exterior of La Quinta Inn & Suites by Wyndham Buffalo Amherst
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Tonawanda/Buffalo
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1120 Niagarafalls Blvd., Tonawanda, NY 14150 ~4.96 miles west of 14221
  • Inexpensive Suburban hotel
  • 2 floors in property
More Photos Image of Days Inn by Wyndham Tonawanda/Buffalo
From$60
Poor 2.0 /5 Reviews Call BookMore Details
Extended Stay America Suites Buffalo Amherst
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
125 Inn Keepers Ln., Amherst, NY 14228 ~5.02 miles west of 14221
  • Economical property
  • Hotel has 3 floors
More Photos Image of Extended Stay America Suites Buffalo Amherst
From$52
Average 3.0 /5 Hotel Reviews Call BookMore Details
Home2 Suites by Hilton Amherst Buffalo in Amherst
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3820 Ridge Lea Rd., Amherst, NY 14228 ~5.07 miles west of 14221
  • 3-star Suburban hotel
  • 111 sleeping rooms in hotel
More Photos Photo of Home2 Suites by Hilton Amherst Buffalo
From$60
Very Good 4.0 /5 Reviews Call BookMore Details
Sleep Inn Amherst - Buffalo North near University
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
75 Inn Keepers Lane, Amherst, NY 14228 ~5.16 miles west of 14221
  • Economical Suburban hotel
  • 5 floors in hotel
More Photos Exterior of Sleep Inn Amherst - Buffalo North near University
From$75
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Baymont by Wyndham Buffalo in Buffalo
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3475 Union Rd., Buffalo, NY 14225 ~5.17 miles south of 14221
  • Low Cost property
  • Check-in: 4pm
More Photos Image of Baymont by Wyndham Buffalo
From$75
Average 3.0 /5 Hotel Reviews Call BookMore Details
M Hotel Buffalo - Buffalo
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
2040 Walden Ave., Buffalo, NY 14225 ~5.21 miles south of 14221
  • Two-star Airport hotel
  • 8 floors in property
More Photos Exterior of M Hotel Buffalo
From$60
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Amherst Inn & Suites
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1951 Niagara Falls Blvd., Amherst, NY 14228 ~5.22 miles west of 14221
  • Economical Downtown hotel
  • Complimentary breakfast is offered
More Photos Photo of Amherst Inn & Suites
From$60
Average 3.5 /5 Review Score Call BookMore Details

Next: Show All Available 14221 Hotels with Pricing

Graph of Williamsville, NY Hotel Prices for Next 20 Days

Rates shown are nightly rates before taxes and do not necessarily reflect all Williamsville, NY discounts available. The chart reflects the cheapest Williamsville hotel for each day and each star rating category.

FAQs about hotels near 14221

What are the most favored hotels near 14221?

Fairfield Inn & Suites by Marriott Buffalo Amherst, Candlewood Suites Buffalo - Amherst by IHG and Homewood Suites by Hilton Buffalo Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels near 14221?

The Mosey Hotel a Tapestry Collection by Hilton, Buffalo Marriott Niagara and Jazzboline are the top 3 luxury hotels near 14221.

What hotels are closest to the area of 14221?

La Quinta Inn by Wyndham Buffalo Airport, Hawthorn Suites by Wyndham Williamsville Buffalo Airport, and Springhill Suites Buffalo Airport are the properties closest to 14221.

How much does a cheap hotel near 14221 cost per night?

In the last year, a 2 star hotel near 14221 can be as cheap as $74.66 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 14221 cost per night?

In the last year, the average 3 star hotel near 14221 has been $97.89 per night. (based on HotelPlanner prices)

How much does a high-end hotel near 14221 cost?

In the last year, the average 4 star hotel near 14221 has been $140.50 per night. (based on HotelPlanner prices)

What are the best independent hotels near 14221?

Jazzboline, Inn at Buffalo Airport and Clarence Inn are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 14221?

Fairfield Inn & Suites by Marriott Buffalo Amherst, Springhill Suites Buffalo Airport and Courtyard by Marriott Buffalo Amherst are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 14221?

Sleep Inn Buffalo Airport, Comfort Inn University and Sleep Inn Amherst - Buffalo North near University are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 14221?

Candlewood Suites Buffalo - Amherst by IHG, Staybridge Suites Buffalo Amherst and Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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