Hotels in 14221 - Buffalo NY

Only hotels in 14221 zip code are listed below. Search for cheap and discount hotel rates in Buffalo, NY for your upcoming leisure or conference / group travel. We list the best 14221 hotels and motels so you can review the Buffalo hotel list below to find the perfect lodging. Hotels in Erie county and area code 716 are also listed.

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14221 Hotels/Motels & Accommodations

La Quinta Inn by Wyndham Buffalo Airport : 6619 Transit Rd. 6619 Transit Rd., Williamsville, NY 14221
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  • 2-star Airport hotel
  • Check in: 03:00 PM
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From$94 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
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Hawthorn Suites by Wyndham Williamsville Buffalo Airport - Williamsville 8005 Sheridan Dr., Williamsville, IN 14221
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  • 3-star Airport hotel
  • Check in time: 4:00PM
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From$96 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Springhill Suites Buffalo Airport 6647 Transit Rd., Buffalo, NY 14221
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  • Mid-scale Suburban property
  • Airport shuttle provided
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From$94 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Fairbridge Inn Express Buffalo Airport Williamsville 7200 Transit Rd., Williamsville, NY 14221
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  • Cheap Airport hotel
  • Hotel has 2 floors
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From$72 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Buffalo-Williamsville - Williamsville 5455 Main St., Williamsville, NY 14221
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  • Affordable Suburban hotel
  • 4 floors in hotel
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From$114 total
Very good 4.0 /5 Reviews Call BookMore Details
The Mosey Hotel a Tapestry Collection by Hilton - Buffalo 5195 Main St., Buffalo, NY 14221
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  • Four star Suburban hotel
  • 120 rooms in property
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From$82 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
Tru by Hilton Williamsville Buffalo Airport - Williamsville 48 Freeman Rd. Building A, Williamsville, NY 14221
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  • Mid-scale Airport hotel
  • 79 sleeping rooms in hotel
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From$90 total
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 Buffalo Ny Airport Williamsville in Buffalo 52 Freeman Rd., Buffalo, NY 14221
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  • Two-star Airport property
  • Hotel has 130 rooms
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From$72 total
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Best Western Buffalo Inn & Suites 50 Freeman Rd., Buffalo, NY 14221
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  • 3-star Airport property
  • 71 sleeping rooms in hotel
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From$86 total
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Garden Place Hotel 6615 Transit Rd., Williamsville, NY 14221
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  • 3-star Airport property
  • 3 floors in hotel
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From$97 total
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Courtyard Marriott : 4100 Sheridan Dr. 4100 Sheridan Dr., Buffalo, NY 14221
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  • Three Star Suburban property
  • 4 floors in hotel
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From$96 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Residence Inn Buffalo Amherst in Amherst 100 Maple Rd., Amherst, NY 14221
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  • 3 star Suburban hotel
  • Hotel has 112 rooms
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From$94 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Amherst / Buffalo : 1601 Amherst Manor Dr. 1601 Amherst Manor Dr., Buffalo, NY 14221
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  • 3 star Suburban hotel
  • Airport shuttle available
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From$96 total
Very good 4.0 /5 Read Reviews Call BookMore Details
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Buffalo Marriott Niagara : 1340 Millersport Highway 1340 Millersport Highway, Amherst, NY 14221
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  • High-end Suburban property
  • Hotel has 10 floors
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From$150 total
Average 3.0 /5 Read Reviews Call BookMore Details
Hyatt Place Buffalo/Amherst : 5020 Main St. 5020 Main St., Amherst, NY 14226
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~2.50 miles southwest of 14221
  • Mid-scale Suburban property
  • 3 suites in hotel
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From$114 total
Very good 4.0 /5 Hotel Reviews Call BookMore Details
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Jazzboline in Amherst 5010 Main St., Amherst, NY 14226
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~2.68 miles southwest of 14221
  • Expensive property
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From$90 total
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Red Roof Inn Buffalo - Niagara Airport in Bowmansville 146 Maple Dr., Bowmansville, NY 14026
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~2.68 miles southeast of 14221
  • Cheap Airport hotel
  • Check in time: 12:00 PM
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From$98 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
Reikart House, Buffalo, a Tribute Portfolio Hotel 5000 Main St., Amherst, NY 14226
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~2.70 miles southwest of 14221
  • High end Suburban property
  • 5 meeting rooms in property
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From$154 total
Very good 4.0 /5 Reviews Call BookMore Details
Sleep Inn & Suites Buffalo Airport 100 Holtz Dr., Cheektowaga, NY 14225
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~3.00 miles south of 14221
  • Inexpensive Airport property
  • Fitness + Health Center
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From$72 total
Very good 4.0 /5 Reviews Call BookMore Details
Inn at Buffalo Airport 4630 Genesee St., Cheektowaga, NY 14225
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~3.13 miles south of 14221
  • Cheap Airport hotel
  • Shuttle from airport available
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From$72 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Buffalo Airport Hotel 4600 Genesee St., Cheektowaga, NY 14225
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~3.15 miles south of 14221
  • 3-star Airport property
  • Hotel has 12 meeting rooms
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From$58 total
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Inn & Suites Buffalo Airport : 4345 Genesee St. 4345 Genesee St., Buffalo, NY 14225
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~3.32 miles south of 14221
  • Affordable Suburban property
  • 129 rooms in hotel
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From$118 total
Average 3.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Buffalo Airport - Buffalo 4271 Genesee St., Buffalo, NY 14225
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~3.34 miles south of 14221
  • Mid-scale Airport property
  • Airport shuttle provided
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From$128 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Courtyard Buffalo Airport - Cheektowaga 4243 Genesee St., Cheektowaga, NY 14225
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~3.40 miles south of 14221
  • Three Star Airport hotel
  • 2 meeting rooms in property
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From$116 total
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Inn University in Amherst 1 Flint Rd., Amherst, NY 14226
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~3.42 miles west of 14221
  • Two-star Suburban property
  • Gym / Fitness Center Available
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From$66 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hilton Garden Inn Buffalo Airport : 4201 Genesee St. 4201 Genesee St., Buffalo, NY 14225
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~3.45 miles south of 14221
  • 3 star Airport hotel
  • 5 conference rooms in property
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From$118 total
Very good 4.0 /5 Hotel Reviews Call BookMore Details
DoubleTree by Hilton Hotel Buffalo - Amherst 10 Flint Rd., Amherst, NY 14226
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~3.46 miles west of 14221
  • Four star Suburban hotel
  • Airport shuttle provided
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From$118 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Red Roof Inn PLUS+ University at Buffalo - Amherst in Amherst 42 Flint Rd., Amherst, NY 14226
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~3.46 miles west of 14221
  • Two-star Suburban hotel
  • 2 floors in hotel
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From$62 total
Poor 2.0 /5 Recent Reviews Call BookMore Details
Towneplace Suites Buffalo Airport 4265 Genesee St., Buffalo, NY 14225
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~3.48 miles south of 14221
  • Three Star Airport hotel
  • Hotel has an eco-friendly policy Read more
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From$130 total
Very good 4.0 /5 Review Score Call BookMore Details
Quality Inn Buffalo Airport - Buffalo 4217 Genesee St., Buffalo, NY 14225
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~3.49 miles south of 14221
  • Inexpensive Airport property
  • Shuttle to airport available
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From$96 total
Poor 2.0 /5 Reviews Call BookMore Details
Aloft by Marriott Buffalo Airport - Cheektowaga 4219 Genesee St., Cheektowaga, NY 14225
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~3.54 miles south of 14221
  • 3-star Airport hotel
  • 153 rooms in hotel
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From$105 total
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Candlewood Suites Buffalo - Amherst by IHG : 20 Flint Rd. 20 Flint Rd., Amherst, NY 14226
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~3.54 miles west of 14221
  • Low Cost Suburban property
  • Check-in time: 3:00pm
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From$72 total
Very good 4.5 /5 Guest Reviews Call BookMore Details
Homewood Suites by Hilton Buffalo/Amherst - Amherst 1138 Millersport Highway, Amherst, NY 14226
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~3.59 miles west of 14221
  • Affordable Suburban hotel
  • Hotel has 5 floors
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From$141 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG 131 Buell Ave., Cheektowaga, NY 14225
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~3.67 miles south of 14221
  • Midscale Airport hotel
  • Check in time: 3:00pm
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From$94 total
Very good 4.0 /5 Latest Reviews Call BookMore Details
Clarence Inn : 9079 Main St. 9079 Main St., Clarence, NY 14032
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~3.72 miles east of 14221
  • Three Star Airport hotel
  • 14 rooms in hotel
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From$57 total
Very good 4.0 /5 Review Score Call BookMore Details
Extended Stay of America 901 Dick Rd., Cheektowaga, NY 14225
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~3.77 miles south of 14221
  • Midscale Airport hotel
  • Access to gym on-site
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From$96 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Motel 6 Amherst, NY - Buffalo - Amherst 4400 Maple Rd., Amherst, NY 14226
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~3.93 miles west of 14221
  • 2 star property
  • 2 floors in hotel
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From$72 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Homewood Suites by Hilton Buffalo Airport 760 Dick Rd., Cheektowaga, NY 14225
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~3.96 miles south of 14221
  • Mid-scale Airport hotel
  • Hotel has an eco-friendly policy Learn more
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From$124 total
Very good 4.5 /5 Latest Reviews Call BookMore Details
Staybridge Suites Buffalo Amherst 1290 Sweet Home Rd., Amherst, NY 14228
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~4.02 miles west of 14221
  • Midscale Suburban property
  • 6 floors in property
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From$102 total
Very good 4.5 /5 Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Buffalo Amherst/University 3880 Rensch Rd. Amherst Ny 14228, Amherst, NY 14228
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~4.04 miles west of 14221
  • 3 star Suburban property
  • 4 floors in hotel
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From$64 total
Excellent 5.0 /5 Latest Reviews Call BookMore Details
Village Haven Inn & Extended Stay : 9370 Main St. 9370 Main St., Clarence, NY 14031
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~4.25 miles east of 14221
  • Low-priced property
  • 40 sleeping rooms in hotel
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From$72 total
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University Manor Inn : 3612 Main St. 3612 Main St., Buffalo, NY 14226
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~4.78 miles west of 14221
  • Low-priced Downtown property
  • 40 rooms in property
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From$48 total
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La Quinta Inn & Suites by Wyndham Buffalo Amherst 145 Innkeepers Lane, Buffalo, NY 14228
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~4.96 miles west of 14221
  • Affordable Suburban hotel
  • Free breakfast available
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From$96 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Tonawanda/Buffalo : 1120 Niagarafalls Blvd. 1120 Niagarafalls Blvd., Tonawanda, NY 14150
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~4.96 miles west of 14221
  • 2-star Suburban property
  • Hotel has 2 floors
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From$72 total
Poor 2.0 /5 Recent Reviews Call BookMore Details
Studio 6 Corporate Extended Stay Buffalo Amherst NY - Amherst 125 Inn Keepers Ln., Amherst, NY 14228
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~5.02 miles west of 14221
  • 2-star hotel
  • Free breakfast available
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From$62 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Home2 Suites by Hilton Amherst Buffalo in Amherst 3820 Ridge Lea Rd., Amherst, NY 14228
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~5.07 miles west of 14221
  • 3-star Suburban hotel
  • Check-in: 3:00 pm
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From$72 total
Very good 4.0 /5 Review Score Call BookMore Details
Sleep Inn Amherst - Buffalo North near University 75 Inn Keepers Lane, Amherst, NY 14228
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~5.16 miles west of 14221
  • Low priced Suburban property
  • Check in: 3:00 PM
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From$90 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Buffalo - Buffalo 3475 Union Rd., Buffalo, NY 14225
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~5.17 miles south of 14221
  • Economy Airport hotel
  • Hotel has an eco-friendly policy See policy
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From$90 total
Average 3.0 /5 Latest Reviews Call BookMore Details
M Hotel Buffalo - Buffalo 2040 Walden Ave., Buffalo, NY 14225
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~5.21 miles south of 14221
  • Low-priced Airport property
  • Check in: 4:00 PM
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From$72 total
Average 3.0 /5 Review Score Call BookMore Details
Amherst Inn & Suites - Amherst 1951 Niagara Falls Blvd., Amherst, NY 14228
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~5.22 miles west of 14221
  • 2-star Downtown hotel
  • Free breakfast available
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From$72 total
Average 3.5 /5 Guest Reviews Call BookMore Details

Next: Show All Available 14221 Hotels with Pricing

Graph of Williamsville, NY Hotel Prices for Next 20 Days

Rates shown are nightly rates before taxes and do not necessarily reflect all Williamsville, NY discounts available. The chart reflects the cheapest Williamsville hotel for each day and each star rating category.

FAQs about hotels near 14221

What are the most favored hotels near 14221?

Fairfield Inn & Suites by Marriott Buffalo Amherst, Candlewood Suites Buffalo - Amherst by IHG and Homewood Suites by Hilton Buffalo Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels near 14221?

The Mosey Hotel a Tapestry Collection by Hilton, Buffalo Marriott Niagara and Jazzboline are the top 3 luxury hotels near 14221.

What hotels are closest to the area of 14221?

La Quinta Inn by Wyndham Buffalo Airport, Hawthorn Suites by Wyndham Williamsville Buffalo Airport, and Springhill Suites Buffalo Airport are the properties closest to 14221.

How much does a cheap hotel near 14221 cost per night?

In the last year, a 2 star hotel near 14221 can be as cheap as $74.66 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 14221 cost per night?

In the last year, the average 3 star hotel near 14221 has been $97.89 per night. (based on HotelPlanner prices)

How much does a high-end hotel near 14221 cost?

In the last year, the average 4 star hotel near 14221 has been $140.50 per night. (based on HotelPlanner prices)

What are the best independent hotels near 14221?

Jazzboline, Inn at Buffalo Airport and Clarence Inn are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 14221?

Fairfield Inn & Suites by Marriott Buffalo Amherst, Springhill Suites Buffalo Airport and Reikart House, Buffalo, a Tribute Portfolio Hotel are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 14221?

Sleep Inn & Suites Buffalo Airport, Comfort Inn University and Sleep Inn Amherst - Buffalo North near University are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 14221?

Candlewood Suites Buffalo - Amherst by IHG, Staybridge Suites Buffalo Amherst and Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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