45621 Hotels & Accommodations

Quality Inn : 605 East Main St.
+1-888-389-4121
605 East Main St., Jackson, OH 45640 +1-888-389-4121 ~5.13 miles south of 45621
  • Mid-scale property
  • Check-in time: 15:00
From$90
Average 3.0 /5 Read Reviews Call BookMore Details
Red Roof Inn Jackson, OH in Jackson
+1-888-675-2083
1000 Acy Ave., Jackson, OH 45640 +1-888-675-2083 ~5.28 miles south of 45621
  • Economical Rural property
  • Fitness / Gym is on-site
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Jackson - Jackson
+1-800-716-8490
972 East Main St., Jackson, OH 45640 +1-800-716-8490 ~5.29 miles south of 45621
  • Inexpensive Rural hotel
  • Free comp. breakfast
From$84
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Inn - Piketon
+1-800-805-5223
7525 Us 23, Piketon, OH 45661 +1-800-805-5223 ~21.71 miles west of 45621
  • Midscale Lake hotel
  • Check in time: 12:00
From$80
Very good 4.0 /5 Recent Reviews Call BookMore Details
Americas Best Value Inn Chillicothe : 1135 East Main St.
+1-888-965-1860
1135 East Main St., Chillicothe, OH 45601 +1-888-965-1860 ~23.79 miles northwest of 45621
  • Low Cost Highway hotel
  • Free comp. breakfast
From$60
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express Chillicothe East by IHG
+1-888-788-5576
1003 East Main St., Chillicothe, OH 45601 +1-888-788-5576 ~23.87 miles northwest of 45621
  • Mid-scale Suburban property
  • Free comp. breakfast
From$87
Very good 4.0 /5 Recent Reviews Call BookMore Details
Christopher Inn and Suites
+1-888-897-9207
30 North Plaza Blvd., Chillicothe, OH 45601 +1-888-897-9207 ~25.44 miles northwest of 45621
  • 3 star Highway property
  • Gym / Fitness Center Available
From$85
Very good 4.5 /5 Recent Reviews Call BookMore Details
Quality Inn
+1-888-311-4278
20 North Plaza Blvd., Chillicothe, OH 45601 +1-888-311-4278 ~25.46 miles northwest of 45621
  • Midscale Highway hotel
  • Check-in time: 12:00
From$80
Very good 4.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn and Suites by Marriott Chillicothe - Chillicothe
+1-888-469-4795
300 North Plaza Blvd., Chillicothe, OH 45601 +1-888-469-4795 ~25.48 miles northwest of 45621
  • Mid-scale property
  • 4 floors in property
From$125
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Chillicothe - Chillicothe
+1-888-734-9421
100 North Plaza Blvd., Chillicothe, OH 45601 +1-888-734-9421 ~25.61 miles northwest of 45621
  • Mid-scale Rural hotel
  • 3 floors in property
From$135
Very good 4.0 /5 Latest Reviews Call BookMore Details
Best Western Adena Inn
+1-888-841-5292
1250 North Bridge St., Chillicothe, OH 45601 +1-888-841-5292 ~25.90 miles northwest of 45621
  • Economy Downtown property
  • 2 floors in property
From$92
Very good 4.0 /5 Read Reviews Call BookMore Details
Travelodge by Wyndham Gallipolis - Gallipolis
+1-888-455-5160
260 Jackson Pike, Gallipolis, OH 45631 +1-888-455-5160 ~27.33 miles southeast of 45621
  • Cheap Rural hotel
  • 2 floors in hotel
From$53
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites
+1-888-965-8297
5100 Scioto Trail, Portsmouth, OH 45662 +1-888-965-8297 ~29.63 miles southwest of 45621
  • Low priced hotel
  • 2 floors in hotel
From$60
Very good 4.0 /5 Read Reviews Call BookMore Details
Quality Inn - Wheelersburg
+1-888-906-6358
8226 Ohio River Rd., Wheelersburg, OH 45694 +1-888-906-6358 ~29.72 miles southwest of 45621
  • Two star property
  • 2 floors in property
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Red Roof Inn Wheelersburg : 8340 Ohio River Rd.
+1-888-749-6785
8340 Ohio River Rd., Wheelersburg, OH 45694 +1-888-749-6785 ~29.92 miles southwest of 45621
  • Low Cost Highway property
  • Free comp. breakfast
From$71
Very good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Portsmouth
+1-888-878-9982
4266 Us Route 23 North, Portsmouth, OH 45622 +1-888-878-9982 ~29.92 miles southwest of 45621
  • Low-priced Rural property
  • 3 floors in property
From$54
Average 3.0 /5 Hotel Reviews Call BookMore Details
Rodeway Inn & Suites - Portsmouth
+1-888-389-4485
3762 Us Highway 23, Portsmouth, OH 45662 +1-888-389-4485 ~30.25 miles southwest of 45621
  • Economical hotel
  • Comp. Breakfast
From$36
Poor 2.0 /5 Reviews Call BookMore Details
Ohio University Inn & Conference Center - Athens
+1-888-389-4121
331 Richland Ave., Athens, OH 45701 +1-888-389-4121 ~30.55 miles east of 45621
  • Midscale Suburban property
  • Check-in: 3:00 PM
From$99
Very good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express Logan An Ihg Hotel
+1-888-675-2083
12916 Grey St., Logan, OH 43138 +1-888-675-2083 ~30.78 miles north of 45621
  • 3 star Rural hotel
  • Gym / Fitness Center Available
From$99
Very good 4.0 /5 Read Reviews Call BookMore Details
Sleep Inn Logan Ohio-Hocking Hills - Logan
+1-800-716-8490
12830 Grey St., Logan, OH 43138 +1-800-716-8490 ~30.92 miles north of 45621
  • Low priced property
  • Hotel has 39 rooms
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Logan - Logan
+1-800-805-5223
12819 Oh 664, Logan, OH 43138 +1-800-805-5223 ~31.05 miles north of 45621
  • 3-star Rural hotel
  • 2 floors in hotel
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn - Gallipolis
+1-888-965-1860
577 State Route 7n, Gallipolis, OH 45631 +1-888-965-1860 ~31.08 miles southeast of 45621
  • 3-star property
  • 3 suites in hotel
From$66
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Gallipolis
+1-888-788-5576
444 State Route 7 South, Gallipolis, OH 45631 +1-888-788-5576 ~31.17 miles southeast of 45621
  • Midscale Rural property
  • Check-in: 3:00 PM
From$105
Very good 4.0 /5 Reviews Call BookMore Details
Super 8 Gallipolis / Pt Pleasant
+1-888-897-9207
321 Upper River Rd., Gallipolis, OH 45631 +1-888-897-9207 ~31.23 miles southeast of 45621
  • Economy Highway hotel
  • 85 rooms in property
From$59
Average 3.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Athens
+1-888-311-4278
330 Columbus Rd., Athens, OH 45701 +1-888-311-4278 ~31.91 miles northeast of 45621
  • Economy Rural hotel
  • Check-in time: 3pm
Quality Inn
+1-888-469-4795
20 Home St., Athens, OH 45701 +1-888-469-4795 ~32.20 miles east of 45621
  • Midscale Rural property
  • 9 suites in hotel
From$80
Very good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express Hotel & Suites Athens, an IHG Hotel
+1-888-734-9421
555 East State St., Athens, OH 45701 +1-888-734-9421 ~32.48 miles east of 45621
  • Three Star Downtown hotel
  • Hotel has a green policy See more
From$75
Very good 4.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites Athens
+1-888-841-5292
924 East State St., Athens, OH 45701 +1-888-841-5292 ~32.89 miles east of 45621
  • 3-star Rural property
  • Check-in time: 3:00pm
From$169
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Portsmouth Downtown, an IHG Hotel : 711 2nd St.
+1-888-455-5160
711 2nd St., Portsmouth, OH 45662 +1-888-455-5160 ~33.49 miles southwest of 45621
  • Mid-scale Downtown hotel
  • 3 meeting rooms in property
From$107
Very good 4.0 /5 Latest Reviews Call BookMore Details
Knights Inn Athens
+1-888-965-8297
997 East State St., Athens, OH 45701 +1-888-965-8297 ~33.51 miles east of 45621
  • Cheap Rural hotel
  • Comp. Breakfast
Super 8 by Wyndham Athens : 2091 East State St.
+1-888-906-6358
2091 East State St., Athens, OH 45701 +1-888-906-6358 ~34.54 miles east of 45621
  • Two-star property
  • 2 floors in property
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites
+1-888-749-6785
24517 Us Highway 23s, Circleville, OH 43113 +1-888-749-6785 ~36.58 miles northwest of 45621
  • Economy Rural hotel
  • Check-in time: 3:00 pm
From$89
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn Circleville
+1-888-878-9982
1520 South Court St., Circleville, OH 45113 +1-888-878-9982 ~37.00 miles northwest of 45621
  • Mid-scale property
  • Gym is available on property
From$90
Very good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Circleville An Ihg Hotel
+1-888-389-4485
23911 Us 23, Circleville, OH 43113 +1-888-389-4485 ~37.16 miles northwest of 45621
  • 3 star Rural property
  • 2 conference rooms in property
From$80
Average 3.0 /5 Review Score Call BookMore Details
Rodeway Inn in Circleville
+1-888-389-4121
23897 Us Route 23 South, Circleville, OH 43113 +1-888-389-4121 ~37.20 miles northwest of 45621
  • Cheap hotel
  • 70 sleeping rooms in hotel
From$60
Poor 2.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Ironton An Ihg Hotel
+1-888-675-2083
401 South 9th St., Ironton, OH 45638 +1-888-675-2083 ~39.98 miles south of 45621
  • 3-star Suburban property
  • 15 suites in property
From$85
Very good 4.0 /5 Recent Reviews Call BookMore Details
Towneplace Suites by Marriott Ironton
+1-800-716-8490
802 Washington St., Ironton, OH 45638 +1-800-716-8490 ~40.00 miles south of 45621
  • 4 star Downtown hotel
  • Hotel has 109 suites
Shawnee Lodge & Conference Center
+1-800-805-5223
4404b State Route 125, West Portsmouth, OH 45663 +1-800-805-5223 ~40.84 miles southwest of 45621
  • Affordable Rural hotel
  • 3 floors in property
From$59
Average 3.0 /5 Read Reviews Call BookMore Details
Burr Oak Lodge & Conference Center
+1-888-965-1860
10660 Burr Oak Lodge Rd., Glouster, OH 45732 +1-888-965-1860 ~42.22 miles northeast of 45621
  • High-end property
  • 22 suites in hotel
From$69
Very good 4.0 /5 Latest Reviews Call BookMore Details
Best Western River Cities - Ashland
+1-888-788-5576
31 Russell Plaza Dr., Ashland, KY 41101 +1-888-788-5576 ~42.57 miles south of 45621
  • Affordable Downtown hotel
  • 58 rooms in hotel
From$89
Very good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Lancaster - Lancaster
+1-888-897-9207
2041 Schorrway Dr., Lancaster, OH 43130 +1-888-897-9207 ~42.85 miles north of 45621
  • 3 star Suburban hotel
  • 78 rooms in hotel
From$79
Very good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites in Lancaster
+1-888-311-4278
1861 Riverway Dr., Lancaster, OH 43130 +1-888-311-4278 ~42.90 miles north of 45621
  • 3 star property
  • Hotel has 63 rooms
From$119
Very good 4.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Lancaster - Lancaster
+1-888-469-4795
1721 River Valley Circle North, Lancaster, OH 43130 +1-888-469-4795 ~42.94 miles north of 45621
  • Economical property
From$60
Very good 4.0 /5 Latest Reviews Call BookMore Details
Delta Hotels by Marriott Ashland Downtown : 1441 Winchester Ave.
+1-888-734-9421
1441 Winchester Ave., Ashland, KY 41101 +1-888-734-9421 ~43.74 miles south of 45621
  • Four-star Downtown hotel
  • Hotel has 3 meeting rooms
From$75
Average 3.0 /5 Latest Reviews Call BookMore Details
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