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45621 Hotels/Motels & Accommodations

Quality Inn
+1-888-389-4121
605 East Main St., Jackson, OH 45640 ~5.14 miles south of 45621
  • Affordable property
  • 2 floors in hotel
From$90
Average 3.0 /5 Hotel Reviews Call BookMore Details
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Red Roof Inn Jackson, OH - Jackson
+1-888-675-2083
1000 Acy Ave., Jackson, OH 45640 ~5.29 miles south of 45621
  • Two star Rural hotel
  • Gym / Fitness Center Available
From$60
Average 3.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Jackson
+1-800-716-8490
972 East Main St., Jackson, OH 45640 ~5.30 miles south of 45621
  • 2 star Rural property
  • 48 rooms in hotel
From$84
Average 3.0 /5 Reviews Call BookMore Details
Comfort Inn : 7525 Us 23
+1-800-805-5223
7525 Us 23, Piketon, OH 45661 ~21.75 miles west of 45621
  • Affordable Lake hotel
  • Check in: 12:00
From$80
Very good 4.0 /5 Guest Reviews Call BookMore Details
Americas Best Value Inn Chillicothe : 1135 East Main St.
+1-888-965-1860
1135 East Main St., Chillicothe, OH 45601 ~23.81 miles northwest of 45621
  • 2-star Highway hotel
  • Check in time: 3:00 pm
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Chillicothe East by IHG
+1-888-788-5576
1003 East Main St., Chillicothe, OH 45601 ~23.89 miles northwest of 45621
  • 3 star Suburban hotel
  • Fitness / Gym is on-site
From$87
Very good 4.0 /5 Guest Reviews Call BookMore Details
Christopher Inn and Suites
+1-888-897-9207
30 North Plaza Blvd., Chillicothe, OH 45601 ~25.45 miles northwest of 45621
  • 3-star Highway property
  • Check in time: 3:00pm
From$85
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Quality Inn
+1-888-311-4278
20 North Plaza Blvd., Chillicothe, OH 45601 ~25.47 miles northwest of 45621
  • Affordable Highway hotel
  • Check-in time: 12:00
From$80
Very good 4.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn and Suites by Marriott Chillicothe : 300 North Plaza Blvd.
+1-888-469-4795
300 North Plaza Blvd., Chillicothe, OH 45601 ~25.49 miles northwest of 45621
  • Three Star hotel
  • 33 suites in property
From$125
Very good 4.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Chillicothe - Chillicothe
+1-888-734-9421
100 North Plaza Blvd., Chillicothe, OH 45601 ~25.62 miles northwest of 45621
  • Three Star Rural hotel
  • 71 rooms in property
From$135
Very good 4.0 /5 Latest Reviews Call BookMore Details
Best Western Adena Inn
+1-888-841-5292
1250 North Bridge St., Chillicothe, OH 45601 ~25.92 miles northwest of 45621
  • Two star Downtown hotel
  • Check-in: 03:00
From$92
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Travelodge by Wyndham Gallipolis
+1-888-455-5160
260 Jackson Pike, Gallipolis, OH 45631 ~27.40 miles southeast of 45621
  • Economy Rural property
  • Check in time: 3:00 PM
From$53
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites : 5100 Scioto Trail
+1-888-965-8297
5100 Scioto Trail, Portsmouth, OH 45662 ~29.71 miles southwest of 45621
  • Low priced property
  • Check-in time: 3:00 PM
From$60
Very good 4.0 /5 Latest Reviews Call BookMore Details
Quality Inn
+1-888-906-6358
8226 Ohio River Rd., Wheelersburg, OH 45694 ~29.77 miles southwest of 45621
  • Inexpensive hotel
  • Check in time: 15:00
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Red Roof Inn Portsmouth - Wheelersburg in Wheelersburg
+1-888-749-6785
8340 Ohio River Rd., Wheelersburg, OH 45694 ~29.98 miles southwest of 45621
  • Low Cost Highway property
  • 53 rooms in property
From$71
Very good 4.0 /5 Read Reviews Call BookMore Details
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Super 8 by Wyndham Portsmouth - Portsmouth
+1-888-878-9982
4266 Us Route 23 North, Portsmouth, OH 45622 ~29.99 miles southwest of 45621
  • Low priced Rural hotel
  • 51 rooms in property
From$54
Average 3.0 /5 Read Reviews Call BookMore Details
Rodeway Inn & Suites : 3762 Us Highway 23
+1-888-389-4485
3762 Us Highway 23, Portsmouth, OH 45662 ~30.33 miles southwest of 45621
  • Low priced hotel
  • Fitness / Gym is on-site
Ohio University Inn & Conference Center : 331 Richland Ave.
+1-888-389-4121
331 Richland Ave., Athens, OH 45701 ~30.56 miles east of 45621
  • Mid-scale Suburban hotel
  • Hotel has an eco-friendly policy See more
From$99
Very good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Logan An Ihg Hotel : 12916 Grey St.
+1-888-675-2083
12916 Grey St., Logan, OH 43138 ~30.82 miles north of 45621
  • 3 star Rural hotel
  • 15 suites in property
From$99
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Sleep Inn Logan Ohio-Hocking Hills
+1-800-716-8490
12830 Grey St., Logan, OH 43138 ~30.96 miles north of 45621
  • Economical property
  • Fitness center on property
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Logan : 12819 Oh 664
+1-800-805-5223
12819 Oh 664, Logan, OH 43138 ~31.09 miles north of 45621
  • Midscale Rural property
  • 58 sleeping rooms in hotel
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn
+1-888-965-1860
577 State Route 7n, Gallipolis, OH 45631 ~31.17 miles southeast of 45621
  • Midscale hotel
  • Hotel has 3 suites
From$66
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn Gallipolis
+1-888-788-5576
444 State Route 7 South, Gallipolis, OH 45631 ~31.26 miles southeast of 45621
  • 3-star Rural hotel
  • Gym / Fitness Center Available
From$105
Very good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 Gallipolis / Pt Pleasant - Gallipolis
+1-888-897-9207
321 Upper River Rd., Gallipolis, OH 45631 ~31.32 miles southeast of 45621
  • Cheap Highway hotel
  • 3 floors in hotel
From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Athens
+1-888-311-4278
330 Columbus Rd., Athens, OH 45701 ~31.91 miles northeast of 45621
  • Inexpensive Rural property
  • Check-in: 3pm
Quality Inn - Athens
+1-888-469-4795
20 Home St., Athens, OH 45701 ~32.20 miles east of 45621
  • Three Star Rural property
  • Hotel has 9 suites
From$80
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Athens, an IHG Hotel : 555 East State St.
+1-888-734-9421
555 East State St., Athens, OH 45701 ~32.49 miles east of 45621
  • Midscale Downtown property
  • Complimentary breakfast is offered
From$75
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites Athens
+1-888-841-5292
924 East State St., Athens, OH 45701 ~32.90 miles east of 45621
  • 3-star Rural hotel
  • Gym is available on property
From$169
Very good 4.0 /5 Review Score Call BookMore Details
Knights Inn Athens
+1-888-455-5160
997 East State St., Athens, OH 45701 ~33.51 miles east of 45621
  • Two-star Rural hotel
  • Check-in time: 3:00 PM
Holiday Inn Portsmouth Downtown, an IHG Hotel : 711 2nd St.
+1-888-965-8297
711 2nd St., Portsmouth, OH 45662 ~33.57 miles southwest of 45621
  • Midscale Downtown hotel
  • Check in: 3:00pm
From$107
Very good 4.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Athens - Athens
+1-888-906-6358
2091 East State St., Athens, OH 45701 ~34.55 miles east of 45621
  • Inexpensive property
  • Hotel has 2 floors
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites
+1-888-749-6785
24517 Us Highway 23s, Circleville, OH 43113 ~36.60 miles northwest of 45621
  • Two star Rural property
  • Check in: 3:00 pm
From$89
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Circleville
+1-888-878-9982
1520 South Court St., Circleville, OH 45113 ~37.03 miles northwest of 45621
  • Midscale property
  • Check in time: 15:00
From$90
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Circleville An Ihg Hotel - Circleville
+1-888-389-4485
23911 Us 23, Circleville, OH 43113 ~37.19 miles northwest of 45621
  • 3-star Rural property
  • Has environment-friendly policy See policy
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Rodeway Inn
+1-888-389-4121
23897 Us Route 23 South, Circleville, OH 43113 ~37.23 miles northwest of 45621
  • Inexpensive property
  • Check-in time: 03:00pm
From$60
Poor 2.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Ironton An Ihg Hotel
+1-888-675-2083
401 South 9th St., Ironton, OH 45638 ~40.03 miles south of 45621
  • Midscale Suburban hotel
  • 15 suites in hotel
From$85
Very good 4.0 /5 Guest Reviews Call BookMore Details
Towneplace Suites by Marriott Ironton
+1-800-716-8490
802 Washington St., Ironton, OH 45638 ~40.06 miles south of 45621
  • Four-star Downtown property
  • 5 floors in hotel
From$75
Poor 2.0 /5 Reviews Call BookMore Details
Shawnee Lodge & Conference Center : 4404b State Route 125
+1-800-805-5223
4404b State Route 125, West Portsmouth, OH 45663 ~40.96 miles southwest of 45621
  • 3 star Rural property
  • 3 floors in hotel
From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
Burr Oak Lodge & Conference Center in Glouster
+1-888-965-1860
10660 Burr Oak Lodge Rd., Glouster, OH 45732 ~42.21 miles northeast of 45621
  • Expensive hotel
  • Check in: 15:30
From$69
Very good 4.0 /5 Recent Reviews Call BookMore Details
Best Western River Cities
+1-888-788-5576
31 Russell Plaza Dr., Ashland, KY 41101 ~42.64 miles south of 45621
  • 3-star Downtown property
  • 58 sleeping rooms in hotel
From$89
Very good 4.0 /5 Reviews Call BookMore Details
Hampton Inn Lancaster in Lancaster
+1-888-897-9207
2041 Schorrway Dr., Lancaster, OH 43130 ~42.91 miles north of 45621
  • 3 star Suburban hotel
  • 78 sleeping rooms in hotel
From$79
Very good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites : 1861 Riverway Dr.
+1-888-311-4278
1861 Riverway Dr., Lancaster, OH 43130 ~42.97 miles north of 45621
  • Three Star property
  • Hotel has 63 rooms
From$119
Very good 4.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Lancaster in Lancaster
+1-888-469-4795
1721 River Valley Circle North, Lancaster, OH 43130 ~43.00 miles north of 45621
  • Economical property
  • Check-in: 12:00 PM
From$60
Very good 4.0 /5 Reviews Call BookMore Details
Delta Hotels by Marriott Ashland Downtown
+1-888-734-9421
1441 Winchester Ave., Ashland, KY 41101 ~43.80 miles south of 45621
  • High end Downtown hotel
  • Gym is available on property
From$75
Average 3.0 /5 Reviews Call BookMore Details

Next: Show All Available 45621 Hotels with Pricing

Graph: Next 20 Days of Jackson Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Jackson, OH discounts available. The chart reflects the cheapest Jackson hotel for each day and each star rating category.

FAQs about hotels near 45621

What are the top reviewed hotels near 45621?

Christopher Inn and Suites, Comfort Inn and Holiday Inn Express Chillicothe East by IHG are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 45621?

Towneplace Suites by Marriott Ironton, Burr Oak Lodge & Conference Center and Delta Hotels by Marriott Ashland Downtown are the top 3 luxury hotels near 45621.

What hotels are closest to the area of 45621?

Quality Inn, Red Roof Inn Jackson, OH, and Days Inn by Wyndham Jackson are the properties closest to 45621.

How much does a 3 star hotel near 45621 cost per night?

In the last year, the average 3 star hotel near 45621 has been $95.00 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 45621?

Christopher Inn and Suites, Ohio University Inn & Conference Center and Burr Oak Lodge & Conference Center are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 45621?

Fairfield Inn and Suites by Marriott Chillicothe, Fairfield Inn & Suites Athens and Towneplace Suites by Marriott Ironton are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 45621?

Comfort Inn, Quality Inn and Quality Inn & Suites are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best Best Western hotels near 45621?

Best Western Adena Inn and Best Western River Cities are the best rated Best Western branded hotels (based on user reviews score).

What are the best IHG hotels near 45621?

Holiday Inn Express Chillicothe East by IHG, Holiday Inn Express Logan An Ihg Hotel and Holiday Inn Express Hotel & Suites Athens, an IHG Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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