Star Rating
Hotel Name
Price Range (USD) to
Amenities
+ More

45621 Hotels & Accommodations

Quality Inn : 605 East Main St.
+1-888-389-4121
605 East Main St., Jackson, OH 45640 ~5.14 miles south of 45621
  • Three Star property
  • Hotel has 52 rooms
From$90
Average 3.0 /5 Latest Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 45621" Get Alexa Skill →
Red Roof Inn Jackson, OH in Jackson
+1-888-675-2083
1000 Acy Ave., Jackson, OH 45640 ~5.29 miles south of 45621
  • Two star Rural hotel
  • Fitness / Gym is on-site
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Jackson in Jackson
+1-800-716-8490
972 East Main St., Jackson, OH 45640 ~5.30 miles south of 45621
  • Two star Rural hotel
  • 2 floors in property
From$84
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn : 7525 Us 23
+1-800-805-5223
7525 Us 23, Piketon, OH 45661 ~21.75 miles west of 45621
  • 3 star Lake hotel
  • 70 rooms in property
From$80
Very Good 4.0 /5 Reviews Call BookMore Details
Americas Best Value Inn Chillicothe : 1135 East Main St.
+1-888-965-1860
1135 East Main St., Chillicothe, OH 45601 ~23.81 miles northwest of 45621
  • Economical Highway property
  • 43 rooms in property
From$60
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express Chillicothe East, an IHG Hotel
+1-888-788-5576
1003 East Main St., Chillicothe, OH 45601 ~23.89 miles northwest of 45621
  • Affordable Suburban hotel
  • Hotel has 58 rooms
From$87
Very Good 4.0 /5 Read Reviews Call BookMore Details
Christopher Inn and Suites
+1-888-897-9207
30 North Plaza Blvd., Chillicothe, OH 45601 ~25.45 miles northwest of 45621
  • 3 star Highway hotel
  • 60 rooms in property
From$85
Very Good 4.5 /5 Reviews Call BookMore Details
Quality Inn
+1-888-311-4278
20 North Plaza Blvd., Chillicothe, OH 45601 ~25.47 miles northwest of 45621
  • Three Star Highway property
  • Fitness + Health Center
From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn and Suites by Marriott Chillicothe in Chillicothe
+1-888-469-4795
300 North Plaza Blvd., Chillicothe, OH 45601 ~25.49 miles northwest of 45621
  • Three Star property
  • Hotel has 33 suites
From$125
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Chillicothe
+1-888-734-9421
100 North Plaza Blvd., Chillicothe, OH 45601 ~25.62 miles northwest of 45621
  • Three Star Rural property
  • Hotel has 3 floors
From$135
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Best Western Adena Inn
+1-888-841-5292
1250 North Bridge St., Chillicothe, OH 45601 ~25.92 miles northwest of 45621
  • Economical Downtown hotel
  • 2 suites in property
From$92
Very Good 4.0 /5 Reviews Call BookMore Details
Travelodge by Wyndham Gallipolis - Gallipolis
+1-888-455-5160
260 Jackson Pike, Gallipolis, OH 45631 ~27.40 miles southeast of 45621
  • Inexpensive Rural hotel
  • Hotel has 45 rooms
From$53
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites in Portsmouth
+1-888-965-8297
5100 Scioto Trail, Portsmouth, OH 45662 ~29.71 miles southwest of 45621
  • Economy hotel
  • Check in: 3:00 PM
From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn
+1-888-906-6358
8226 Ohio River Rd., Wheelersburg, OH 45694 ~29.77 miles southwest of 45621
  • Two-star hotel
  • 52 rooms in property
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Red Roof Inn Portsmouth - Wheelersburg - Wheelersburg
+1-888-749-6785
8340 Ohio River Rd., Wheelersburg, OH 45694 ~29.98 miles southwest of 45621
  • Low Cost Highway hotel
  • Check in time: 3:00 PM
From$71
Very Good 4.0 /5 Reviews Call BookMore Details
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 45621" Get Alexa Skill →
Super 8 by Wyndham Portsmouth
+1-888-878-9982
4266 Us Route 23 North, Portsmouth, OH 45622 ~29.99 miles southwest of 45621
  • Inexpensive Rural hotel
  • Hotel has 3 floors
From$54
Average 3.0 /5 Reviews Call BookMore Details
Rodeway Inn & Suites : 3762 Us Highway 23
+1-888-389-4485
3762 Us Highway 23, Portsmouth, OH 45662 ~30.33 miles southwest of 45621
  • Low Cost hotel
  • 80 rooms in hotel
Ohio University Inn & Conference Center
+1-888-389-4121
331 Richland Ave., Athens, OH 45701 ~30.56 miles east of 45621
  • 3 star Suburban hotel
  • 4 suites in hotel
From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Logan An Ihg Hotel
+1-888-675-2083
12916 Grey St., Logan, OH 43138 ~30.82 miles north of 45621
  • Midscale Rural property
  • Hotel has 3 floors
From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Sleep Inn Logan Ohio-Hocking Hills - Logan
+1-800-716-8490
12830 Grey St., Logan, OH 43138 ~30.96 miles north of 45621
  • Low priced property
  • Hotel has 39 rooms
From$60
Average 3.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Logan
+1-800-805-5223
12819 Oh 664, Logan, OH 43138 ~31.09 miles north of 45621
  • 3-star Rural property
  • 58 rooms in hotel
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn
+1-888-965-1860
577 State Route 7n, Gallipolis, OH 45631 ~31.17 miles southeast of 45621
  • Midscale property
  • 2 floors in hotel
From$66
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Gallipolis in Gallipolis
+1-888-788-5576
444 State Route 7 South, Gallipolis, OH 45631 ~31.26 miles southeast of 45621
  • 3-star Rural property
  • 3 floors in hotel
From$105
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Super 8 Gallipolis / Pt Pleasant in Gallipolis
+1-888-897-9207
321 Upper River Rd., Gallipolis, OH 45631 ~31.32 miles southeast of 45621
  • Low-priced Highway hotel
  • 3 suites in property
From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Athens : 330 Columbus Rd.
+1-888-311-4278
330 Columbus Rd., Athens, OH 45701 ~31.91 miles northeast of 45621
  • Cheap Rural hotel
  • Fitness + Health Center
Quality Inn : 20 Home St.
+1-888-469-4795
20 Home St., Athens, OH 45701 ~32.20 miles east of 45621
  • Midscale Rural property
  • 98 rooms in hotel
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Athens, an IHG Hotel in Athens
+1-888-734-9421
555 East State St., Athens, OH 45701 ~32.49 miles east of 45621
  • Affordable Downtown property
  • Check in time: 3:00 PM
From$75
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites Athens - Athens
+1-888-841-5292
924 East State St., Athens, OH 45701 ~32.90 miles east of 45621
  • 3-star Rural property
  • Comp. Breakfast
From$169
Very Good 4.0 /5 Reviews Call BookMore Details
Knights Inn Athens in Athens
+1-888-455-5160
997 East State St., Athens, OH 45701 ~33.51 miles east of 45621
  • Two star Rural property
  • Hotel has an eco-friendly policy Learn more
From$60
Poor 2.0 /5 Reviews Call BookMore Details
Holiday Inn Downtown Portsmouth - Portsmouth
+1-888-965-8297
711 2nd St., Portsmouth, OH 45662 ~33.57 miles southwest of 45621
  • 3 star Downtown property
  • 3 meeting rooms in property
From$107
Very Good 4.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Athens - Athens
+1-888-906-6358
2091 East State St., Athens, OH 45701 ~34.55 miles east of 45621
  • Inexpensive hotel
  • Hotel has 2 floors
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites
+1-888-749-6785
24517 Us Highway 23s, Circleville, OH 43113 ~36.60 miles northwest of 45621
  • 2-star Rural property
  • Free comp. breakfast
From$89
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn Circleville
+1-888-878-9982
1520 South Court St., Circleville, OH 45113 ~37.03 miles northwest of 45621
  • Three Star property
  • Gym is available on property
From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express Circleville, an IHG Hotel - Circleville
+1-888-389-4485
23911 Us Rt 23 South, Circleville, OH 43113 ~37.13 miles northwest of 45621
  • 3-star Rural property
  • 3 floors in hotel
From$119
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Rodeway Inn in Circleville
+1-888-389-4121
23897 Us Route 23 South, Circleville, OH 43113 ~37.23 miles northwest of 45621
  • Economy property
  • 70 rooms in hotel
Holiday Inn Express & Suites Ironton, an IHG Hotel - Ironton
+1-888-675-2083
401 South 9th St., Ironton, OH 45638 ~40.03 miles south of 45621
  • 3-star Suburban property
  • Hotel has 15 suites
From$85
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Towneplace Suites by Marriott Ironton - Ironton
+1-800-716-8490
802 Washington St., Ironton, OH 45638 ~40.06 miles south of 45621
  • Four-star Downtown property
  • Hotel has an eco-friendly policy Read more
From$75
Poor 2.0 /5 Reviews Call BookMore Details
Shawnee Lodge & Conference Center in West Portsmouth
+1-800-805-5223
4404b State Route 125, West Portsmouth, OH 45663 ~40.96 miles southwest of 45621
  • 3-star Rural property
  • 6 conference rooms in property
From$59
Average 3.0 /5 Latest Reviews Call BookMore Details
Burr Oak Lodge & Conference Center
+1-888-965-1860
10660 Burr Oak Lodge Rd., Glouster, OH 45732 ~42.21 miles northeast of 45621
  • 4 star property
  • 36 sleeping rooms in hotel
From$69
Very Good 4.0 /5 Reviews Call BookMore Details
Best Western River Cities in Ashland
+1-888-788-5576
31 Russell Plaza Dr., Ashland, KY 41101 ~42.64 miles south of 45621
  • Three Star Downtown hotel
  • 6 suites in property
From$89
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn - Lancaster
+1-888-897-9207
2041 Schorrway Dr., Lancaster, OH 43130 ~42.91 miles north of 45621
  • 3-star Suburban hotel
  • 3 floors in property
From$79
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites : 1861 Riverway Dr.
+1-888-311-4278
1861 Riverway Dr., Lancaster, OH 43130 ~42.97 miles north of 45621
  • 3 star hotel
  • Hotel has 3 floors
From$119
Very Good 4.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Lancaster
+1-888-469-4795
1721 River Valley Circle North, Lancaster, OH 43130 ~43.00 miles north of 45621
  • 2-star hotel
From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Delta Hotels by Marriott Ashland Downtown - Ashland
+1-888-734-9421
1441 Winchester Ave., Ashland, KY 41101 ~43.80 miles south of 45621
  • High end Downtown property
  • 6 suites in hotel
From$75
Average 3.0 /5 Recent Reviews Call BookMore Details

Next: Show All Available 45621 Hotels with Pricing

Graph: Next 20 Days of Jackson Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Jackson, OH discounts available. The chart reflects the cheapest Jackson hotel for each day and each star rating category.

FAQs about hotels near 45621

What are the top reviewed hotels near 45621?

Christopher Inn and Suites, Comfort Inn and Holiday Inn Express Chillicothe East, an IHG Hotel are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 45621?

Towneplace Suites by Marriott Ironton, Burr Oak Lodge & Conference Center and Delta Hotels by Marriott Ashland Downtown are the top 3 luxury hotels near 45621.

What hotels are closest to the area of 45621?

Quality Inn, Red Roof Inn Jackson, OH, and Days Inn by Wyndham Jackson are the properties closest to 45621.

How much does a 3 star hotel near 45621 cost per night?

In the last year, the average 3 star hotel near 45621 has been $95.00 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 45621?

Christopher Inn and Suites, Ohio University Inn & Conference Center and Burr Oak Lodge & Conference Center are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 45621?

Fairfield Inn and Suites by Marriott Chillicothe, Fairfield Inn & Suites Athens and Towneplace Suites by Marriott Ironton are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 45621?

Comfort Inn, Quality Inn and Quality Inn & Suites are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best Best Western hotels near 45621?

Best Western Adena Inn and Best Western River Cities are the best rated Best Western branded hotels (based on user reviews score).

What are the best IHG hotels near 45621?

Holiday Inn Express Chillicothe East, an IHG Hotel, Holiday Inn Express Logan An Ihg Hotel and Holiday Inn Express Hotel & Suites Athens, an IHG Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Back to Top