Hotels in 29541 - Effingham SC

Only hotels in 29541 zip code are listed below. Search for cheap and discount hotel rates in Effingham, SC for your upcoming leisure or conference / group travel. We list the best 29541 hotels and motels so you can review the Effingham hotel list below to find the perfect lodging. Hotels in Florence county and area code 843 are also listed.

29541 Hotels/Accommodations

Super 8 by Wyndham Florence SC I-95 North / Hwy 76 - Florence
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
3783a West Palmetto St., Florence, SC 29501 +1-888-389-4121 ~7.10 miles northwest of 29541
  • Two-star Highway hotel
  • Hotel has 120 rooms
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From$58
Not Good 1.0 /5 Reviews Call BookMore Details
Days Inn Florence - Florence
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
3783 West Palmetto St. I 95, Florence, SC 29501 +1-888-675-2083 ~7.11 miles northwest of 29541
  • Economical Highway hotel
  • Check-in: 2pm
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From$39
Poor 2.5 /5 Reviews Call BookMore Details
Travelodge by Wyndham Florence - Florence
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1084 Oregon Coast Highway, Florence, OR 97439 +1-800-716-8490 ~7.19 miles northwest of 29541
  • Low priced property
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From$99
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
3783a West Palmetto St., Florence, SC 29502 +1-800-805-5223 ~7.19 miles northwest of 29541
  • Economy Highway property
  • Complimentary breakfast is offered
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From$60
Not Good 1.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn & Suites Florence
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
527 Woody Jones Blvd., Sc 554, SC 29501 +1-888-965-1860 ~7.51 miles northwest of 29541
  • 3 star Suburban hotel
  • 3 floors in hotel
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From$80
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Florence I-20
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
501 Woody Jones Blvd., Florence, SC 29501 +1-888-788-5576 ~7.52 miles north of 29541
  • Affordable Convention Center hotel
  • 86 rooms in hotel
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From$99
Average 3.0 /5 Review Score Call BookMore Details
Towneplace Suites by Marriott Florence
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2650 Hospitality Blvd., Florence, SC 29501 +1-888-897-9207 ~7.60 miles north of 29541
  • Midscale Suburban hotel
  • 89 suites in hotel
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Home2 Suites by Hilton Florence, SC in Florence
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
900 Woody Jones Blvd., Florence, SC 29501 +1-888-311-4278 ~7.65 miles northwest of 29541
  • Mid-scale Convention Center hotel
  • Hotel has an eco-friendly policy Read more
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From$89
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Springhill Suites in Florence
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2670 Hospitality Blvd., Florence, SC 29501 +1-888-469-4795 ~7.68 miles northwest of 29541
  • 3-star Convention Center hotel
  • Check-in time: 4:00pm
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From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Accident in Florence
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
Florence Sc Usa, Florence, SC 29464 +1-888-734-9421 ~7.69 miles north of 29541
  • 3-star hotel
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From$307
Average 3.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn Florence - Civic Center : 2690 David Mcleod Blvd.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2690 David Mcleod Blvd., Florence, SC 29501 +1-888-841-5292 ~7.71 miles north of 29541
  • Luxury 5-star Highway hotel
  • Airport shuttle available
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From$61
Average 3.0 /5 Latest Reviews Call BookMore Details
Residence Inn Marriott Florence : 2660 Hospitality Blvd.
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
2660 Hospitality Blvd., Florence, SC 29501 +1-888-455-5160 ~7.73 miles northwest of 29541
  • 3-star Suburban property
  • Gym / Fitness Center Available
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From$94
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hotel Florence, Tapestry Collection by Hilton in Florence
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
126 West Evans St., Florence, SC 29501 +1-888-965-8297 ~7.78 miles north of 29541
  • Three Star Downtown property
  • Fitness + Health Center
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From$114
Very Good 4.0 /5 Reviews Call BookMore Details
Hyatt Place Florence Downtown
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
100 East Evans St., Florence, SC 29501 +1-888-906-6358 ~7.79 miles north of 29541
  • Midscale Downtown hotel
  • 2 meeting rooms in hotel
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From$124
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH : 3440 West Radio Dr.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3440 West Radio Dr., Florence, SC 29501 +1-888-749-6785 ~7.84 miles northwest of 29541
  • Affordable Convention Center hotel
  • Check in time: 3:00 PM
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From$95
Very Good 4.0 /5 Review Score Call BookMore Details
Courtyard by Marriott Florence in Florence
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
2680 Hospitality Blvd., Florence, SC 29501 +1-888-878-9982 ~7.85 miles north of 29541
  • Mid-scale Convention Center property
  • Gym is available on property
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From$99
Average 3.0 /5 Read Reviews Call BookMore Details
Hilton Garden Inn
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
2671 Hospitality Blvd., Florence, SC 29501 +1-888-389-4485 ~7.86 miles north of 29541
  • Affordable Highway property
  • Hotel has 186 rooms
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From$109
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Staybridge Suites
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
150 Westpark Dr., Florence, SC 29501 +1-888-389-4121 ~7.87 miles northwest of 29541
  • 3 star Convention Center property
  • Free comp. breakfast
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From$133
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Homewood Suites by Hilton Florence in Florence
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
3450 West Radio Dr., Florence, SC 29501 +1-888-675-2083 ~7.98 miles northwest of 29541
  • 3-star Convention Center property
  • Check-in: 3:00 pm
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From$80
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Florence Center
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
3000 West Radio Dr., Florence, SC 29501 +1-800-716-8490 ~8.01 miles north of 29541
  • Midscale Convention Center property
  • Check in: 3:00 p.m.
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From$109
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Florence Near Civic Center
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
140 Dunbarton Dr., Florence, SC 29501 +1-800-805-5223 ~8.11 miles northwest of 29541
  • 2-star Convention Center property
  • Check in: 3:00pm
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From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Civic Center - Florence
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
150 Dunbarton Dr., Florence, SC 29501 +1-888-965-1860 ~8.14 miles northwest of 29541
  • 2-star Highway property
  • Hotel has 15 suites
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From$60
Average 3.0 /5 Reviews Call BookMore Details
Rodeway Inn & Suites in Florence
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
181 West Lucas St., Florence, SC 29501 +1-888-788-5576 ~8.30 miles north of 29541
  • Cheap property
  • Free breakfast
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From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IH in Florence
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2101 Florence Harllee Blvd., Florence, SC 29506 +1-888-897-9207 ~9.09 miles north of 29541
  • 3-star Suburban property
  • Free comp. breakfast
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From$94
Very Good 4.0 /5 Review Score Call BookMore Details
Best Western Inn - Florence
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1808 West Lucas St., Florence, SC 29501 +1-888-311-4278 ~9.77 miles north of 29541
  • 2-star Highway property
  • Hotel has an eco-friendly policy Read more
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From$59
Average 3.5 /5 Reviews Call BookMore Details
Baymont Inn & Suites Florence by Wyndham
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1826 West Lucas St., Florence, SC 29501 +1-888-469-4795 ~9.78 miles north of 29541
  • Low Cost Highway hotel
  • 5 suites in property
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From$55
Poor 2.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Florence
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1832 1 / 2 Lucas St., Florence, SC 29501 +1-888-734-9421 ~9.81 miles north of 29541
  • 2-star Highway property
  • Check in: 11:00 AM
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From$60
Average 3.0 /5 Review Score Call BookMore Details
Knights Inn Florence
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1834 West Lucas St., Florence, SC 29501 +1-888-841-5292 ~9.85 miles north of 29541
  • Economy property
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From$50
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Fairview Inn Florence
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1811 West Lucas St., Florence, SC 29501 +1-888-455-5160 ~9.89 miles north of 29541
  • Low priced Highway property
  • 2 floors in hotel
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From$40
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Clarion Inn & Suites
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1819 Building a West Lucas St., Florence, SC 29501 +1-888-965-8297 ~10.00 miles north of 29541
  • Midscale Highway hotel
  • Check-in: 3:00
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From$80
Average 3.0 /5 Reviews Call BookMore Details
Mainstay Suites Florence Sc in Florence
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1819 West Lucas St. Building B, Florence, SC 29501 +1-888-906-6358 ~10.00 miles north of 29541
  • Low Cost Highway hotel
  • Hotel has 15 suites
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Florence, SC in Florence
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
2004 West Lucas St., Florence, SC 29501 +1-888-749-6785 ~10.04 miles north of 29541
  • 2 star Downtown property
  • Check in: 3pm
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From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Park Inn by Radisson Florence Sc
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1729 Mandeville Rd., Florence, SC 27407 +1-888-878-9982 ~10.06 miles north of 29541
  • Mid-scale property
  • Fitness + Health Center
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From$90
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Park Inn by Radisson
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1729 Mandeville Rd., Florence, SC 29501 +1-888-389-4485 ~10.06 miles north of 29541
  • Low-priced Highway hotel
  • Fitness / Gym is on-site
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From$75
Average 3.0 /5 Recent Reviews Call BookMore Details
Country Inn & Suites by Radisson, Florence, SC : 1739 Mandeville Rd.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1739 Mandeville Rd., Florence, SC 29501 +1-888-389-4121 ~10.11 miles north of 29541
  • Midscale Highway property
  • 80 suites in property
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From$79
Very Good 4.0 /5 Reviews Call BookMore Details
Suburban Studios Florence - Darlington
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1914 West Lucas St., Florence, SC 29501 +1-888-675-2083 ~10.15 miles north of 29541
  • Cheap Highway hotel
  • Check in time: 3:00 pm
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From$42
Poor 2.0 /5 Guest Reviews Call BookMore Details
Howard Johnson by Wyndham Florence
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
2038 West Lucas St., Florence, SC 29501 +1-800-716-8490 ~10.16 miles north of 29541
  • 2-star Highway hotel
  • 104 rooms in property
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From$60
Poor 2.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Florence North
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1735 Stokes Rd., Florence, SC 29501 +1-800-805-5223 ~10.17 miles north of 29541
  • Cheap Highway hotel
  • 5 floors in property
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From$104
Very Good 4.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Florence / I 95 North : 2111 West Lucas
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
2111 West Lucas, Florence, SC 29501 +1-888-965-1860 ~10.28 miles north of 29541
  • Economy Highway property
  • 103 rooms in hotel
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From$50
Average 3.5 /5 Read Reviews Call BookMore Details
Comfort Suites Florence I-95 in Florence
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2120 West Lucas St., Florence, SC 29501 +1-888-788-5576 ~10.32 miles north of 29541
  • 3 star Highway property
  • Gym is available on property
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From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
TRU by Hilton Florence I 95 - Florence
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2140 West Lucas St., Florence, SC 29501 +1-888-897-9207 ~10.38 miles north of 29541
  • Affordable hotel
  • 5 floors in hotel
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From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Sleep Inn Florence North
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1833 Florence Park Dr., Florence, SC 29501 +1-888-311-4278 ~10.41 miles north of 29541
  • Low-priced Highway hotel
  • Check-in: 3:00pm
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From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Florence in Florence
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2123 West Lucas St., Florence, SC 29501 +1-888-469-4795 ~10.44 miles north of 29541
  • Mid-scale Highway property
  • Access to gym on-site
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From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Florence : 1912 Enterprise Dr.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1912 Enterprise Dr., Florence, SC 29501 +1-888-734-9421 ~10.50 miles north of 29541
  • Economy Highway hotel
  • 83 rooms in hotel
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From$39
Poor 2.5 /5 Hotel Reviews Call BookMore Details
Florence Express Inn in Florence
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
3024 Tv Rd., Florence, SC 29501 +1-888-841-5292 ~12.89 miles north of 29541
  • Cheap Highway hotel
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From$60
Poor 2.5 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites in Lake City
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
202 North Ron Mcnair Blvd., Lake City, SC 29560 +1-888-455-5160 ~14.34 miles south of 29541
  • 3-star property
  • Check in time: 15:00
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From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Inn at the Crossroads
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
128 West Main St., Lake City, SC 29560 +1-888-965-8297 ~14.68 miles south of 29541
  • 2 star Downtown property
  • Free breakfast available
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From$109
Very Good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Lake City in Lake City
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
170 South Ron Mcnair Blvd., Lake City, SC 29560 +1-888-906-6358 ~14.74 miles south of 29541
  • Two star Downtown hotel
  • Check in: 02.00 PM
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From$60
Average 3.5 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Turbeville : 7835 Myrtle Beach Highway
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
7835 Myrtle Beach Highway, Gable, SC 29051 +1-888-749-6785 ~21.87 miles southwest of 29541
  • 2-star property
  • Check in time: 12:00 PM
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From$60
Poor 2.0 /5 Reviews Call BookMore Details
Best Western Executive Inn
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1534 Highway 38 West, Latta, SC 29565 +1-888-878-9982 ~22.76 miles northeast of 29541
  • Mid-scale Highway hotel
  • Check-in: 3:00 PM
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From$69
Very Good 4.0 /5 Latest Reviews Call BookMore Details
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