Hotels in 29541 - Effingham SC

Only hotels in 29541 zip code are listed below. Search for cheap and discount hotel rates in Effingham, SC for your upcoming leisure or conference / group travel. We list the best 29541 hotels and motels so you can review the Effingham hotel list below to find the perfect lodging. Hotels in Florence county and area code 843 are also listed.

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29541 Hotels & Accommodations

Super 8 by Wyndham Florence SC I-95 North / Hwy 76 in Florence 3783a West Palmetto St., Florence, SC 29501
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~7.09 miles northwest of 29541
  • Economical Highway hotel
  • Hotel has 2 floors
More Photos Image of Super 8 by Wyndham Florence SC I-95 North / Hwy 76
From$69 total
Not Good 1.0 /5 Read Reviews Call BookMore Details
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Days Inn Florence 3783 West Palmetto St. I 95, Florence, SC 29501
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~7.10 miles northwest of 29541
  • Economical Highway hotel
  • Check in time: 2pm
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From$46 total
Poor 2.5 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76 3783a West Palmetto St., Florence, SC 29502
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~7.18 miles northwest of 29541
  • 2 star Highway property
  • Check-in time: 11:00 AM
More Photos Image of Super 8 by Wyndham Florence SC I-95 North / Hwy 76
From$72 total
Not Good 1.0 /5 Recent Reviews Call BookMore Details
Travelodge by Wyndham Florence 1084 Oregon Coast Highway, Florence, OR 97439
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~7.18 miles northwest of 29541
  • Inexpensive property
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From$118 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites Florence : 527 Woody Jones Blvd. 527 Woody Jones Blvd., Sc 554, SC 29501
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~7.49 miles northwest of 29541
  • 3 star Suburban hotel
  • 89 rooms in hotel
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From$96 total
Very Good 4.5 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites Florence I 20 501 Woody Jones Blvd., Florence, SC 29501
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~7.57 miles north of 29541
  • Affordable Convention Center hotel
  • Fitness / Gym is on-site
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From$96 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Towneplace Suites by Marriott Florence 2650 Hospitality Blvd., Florence, SC 29501
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~7.59 miles north of 29541
  • Mid-scale Suburban hotel
  • Fitness + Health Center
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From$96 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Home2 Suites by Hilton Florence Sc : 900 Woody Jones Blvd. 900 Woody Jones Blvd., Florence, SC 29501
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~7.64 miles northwest of 29541
  • 3-star Convention Center property
  • 83 rooms in property
More Photos Image of Home2 Suites by Hilton Florence Sc
From$106 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Springhill Suites by Marriott Florence 2670 Hospitality Blvd., Florence, SC 29501
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~7.67 miles northwest of 29541
  • Three Star Convention Center hotel
  • 95 suites in property
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From$96 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Accident : Florence Sc Usa Florence Sc Usa, Florence, SC 29464
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~7.67 miles north of 29541
  • Three Star hotel
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From$368 total
Average 3.0 /5 Reviews Call BookMore Details
Red Roof Inn Florence - Civic Center - Florence 2690 David Mcleod Blvd., Florence, SC 29501
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~7.70 miles north of 29541
  • Luxury 5 star Highway property
  • Check in: 1:00PM
More Photos Image of Red Roof Inn Florence - Civic Center
From$73 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Residence Inn Marriott Florence in Florence 2660 Hospitality Blvd., Florence, SC 29501
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~7.72 miles northwest of 29541
  • Midscale Suburban hotel
  • Check in: 4:00 PM
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From$112 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hotel Florence Tapestry Collection by Hilton 126 West Evans St., Florence, SC 29501
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~7.77 miles north of 29541
  • Midscale Downtown hotel
  • 3 floors in property
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From$118 total
Excellent 5.0 /5 Review Score Call BookMore Details
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Affordable Suites Florence 530 Woody Jones Blvd., Florence, SC 29501
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~7.77 miles northwest of 29541
  • Midscale hotel
  • 2 floors in property
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From$108 total
Average 3.0 /5 Reviews Call BookMore Details
Hyatt Place Florence Downtown in Florence 100 East Evans St., Florence, SC 29501
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~7.78 miles north of 29541
  • Mid-scale Downtown hotel
  • 2 conference rooms in property
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From$148 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
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Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH 3440 West Radio Dr., Florence, SC 29501
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~7.83 miles northwest of 29541
  • Three Star Convention Center property
  • Check-in time: 3:00 PM
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From$114 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Florence in Florence 2680 Hospitality Blvd., Florence, SC 29501
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~7.84 miles north of 29541
  • Three Star Convention Center property
  • 3 floors in property
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From$118 total
Average 3.0 /5 Reviews Call BookMore Details
Hilton Garden Inn 2671 Hospitality Blvd., Florence, SC 29501
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~7.85 miles north of 29541
  • 3-star Highway property
  • 15 suites in hotel
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From$130 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Staybridge Suites 150 Westpark Dr., Florence, SC 29501
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~7.86 miles northwest of 29541
  • Midscale Convention Center hotel
  • Hotel has an eco-friendly policy See policy
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From$159 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Homewood Suites by Hilton Florence 3450 West Radio Dr., Florence, SC 29501
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~7.97 miles northwest of 29541
  • Midscale Convention Center hotel
  • Check-in: 3:00 pm
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From$96 total
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Florence Center : 3000 West Radio Dr. 3000 West Radio Dr., Florence, SC 29501
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~8.00 miles north of 29541
  • Affordable Convention Center hotel
  • Hotel has 3 floors
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From$130 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Florence Near Civic Center 140 Dunbarton Dr., Florence, SC 29501
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~8.10 miles northwest of 29541
  • Inexpensive Convention Center hotel
  • Complimentary breakfast is offered
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From$72 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites Florence Civic Center 150 Dunbarton Dr., Florence, SC 29501
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~8.13 miles northwest of 29541
  • 2-star Highway hotel
  • Fitness + Health Center
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From$72 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Rodeway Inn & Suites in Florence 181 West Lucas St., Florence, SC 29501
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~8.28 miles north of 29541
  • Two-star property
  • Check in time: 3:00 PM
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From$72 total
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih - Florence 2101 Florence Harllee Blvd., Florence, SC 29506
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~9.08 miles north of 29541
  • Mid-scale Suburban hotel
  • Hotel has an eco-friendly policy Learn more
More Photos Image of Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih
From$112 total
Very Good 4.0 /5 Reviews Call BookMore Details
Best Western Inn - Florence 1808 West Lucas St., Florence, SC 29501
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~9.75 miles north of 29541
  • Low-priced Highway hotel
  • Hotel has an eco-friendly policy Learn more
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From$70 total
Average 3.5 /5 Read Reviews Call BookMore Details
Baymont Inn & Suites Florence by Wyndham : 1826 West Lucas St. 1826 West Lucas St., Florence, SC 29501
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~9.77 miles north of 29541
  • Two-star Highway property
  • Comp. Breakfast
More Photos Exterior of Baymont Inn & Suites Florence by Wyndham
From$66 total
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Florence 1832 1 / 2 Lucas St., Florence, SC 29501
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~9.79 miles north of 29541
  • Cheap Highway property
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From$72 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Knights Inn Florence 1834 West Lucas St., Florence, SC 29501
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~9.84 miles north of 29541
  • 2-star hotel
  • Hotel has 109 rooms
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From$60 total
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Fairview Inn Florence : 1811 West Lucas St. 1811 West Lucas St., Florence, SC 29501
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~9.88 miles north of 29541
  • Two-star Highway hotel
  • Shuttle to airport available
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From$48 total
Poor 2.0 /5 Review Score Call BookMore Details
Mainstay Suites Florence Sc in Florence 1819 West Lucas St. Building B, Florence, SC 29501
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~9.99 miles north of 29541
  • 2 star Highway property
  • 15 suites in property
More Photos Image of Mainstay Suites Florence Sc
From$72 total
Average 3.0 /5 Review Score Call BookMore Details
Clarion Inn & Suites Florence - Darlington 1819 Building a West Lucas St., Florence, SC 29501
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~9.99 miles north of 29541
  • Midscale Highway property
  • Free breakfast
More Photos Image of Clarion Inn & Suites Florence - Darlington
From$96 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Motel 6 Florence, SC 2004 West Lucas St., Florence, SC 29501
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~10.02 miles north of 29541
  • Low priced Downtown hotel
  • Check in time: 3pm
More Photos Image of Motel 6 Florence, SC
From$72 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Park Inn by Radisson Florence Sc in Florence 1729 Mandeville Rd., Florence, SC 27407
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~10.05 miles north of 29541
  • Mid-scale hotel
  • 60 rooms in property
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From$108 total
Very Good 4.0 /5 Reviews Call BookMore Details
Park Inn by Radisson 1729 Mandeville Rd., Florence, SC 29501
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~10.05 miles north of 29541
  • Low priced Highway property
  • 3 floors in hotel
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From$90 total
Average 3.0 /5 Read Reviews Call BookMore Details
Spark by Hilton Florence North I-95, SC in Florence 1739 Mandeville Rd., Florence, SC 29501
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~10.09 miles north of 29541
  • Mid-scale Highway property
  • Gym / Fitness Center Available
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From$94 total
Very Good 4.0 /5 Reviews Call BookMore Details
Suburban Studios Florence I-95 - Florence 1914 West Lucas St., Florence, SC 29501
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~10.14 miles north of 29541
  • 2-star Highway hotel
  • Check in time: 3:00 pm
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From$50 total
Poor 2.0 /5 Latest Reviews Call BookMore Details
Howard Johnson by Wyndham Florence 2038 West Lucas St., Florence, SC 29501
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~10.15 miles north of 29541
  • Economy Highway hotel
  • Free comp. breakfast
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From$72 total
Poor 2.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Florence North I 95 1735 Stokes Rd., Florence, SC 29501
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~10.16 miles north of 29541
  • 2 star Highway hotel
  • 6 meeting rooms in hotel
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From$124 total
Very Good 4.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Florence/I-95 North 2111 West Lucas, Florence, SC 29501
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~10.27 miles north of 29541
  • Two star Highway property
  • Hotel has 2 floors
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From$60 total
Average 3.5 /5 Hotel Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Florence - Florence 2123 West Lucas St., Florence, SC 29501
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~10.27 miles north of 29541
  • Affordable Highway hotel
  • Check in: 2:00 pm
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From$98 total
Very Good 4.0 /5 Reviews Call BookMore Details
Comfort Suites Florence I 95 : 2120 West Lucas St. 2120 West Lucas St., Florence, SC 29501
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~10.31 miles north of 29541
  • Affordable Highway property
  • Free breakfast
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From$96 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
TRU by Hilton Florence I 95 in Florence 2140 West Lucas St., Florence, SC 29501
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~10.36 miles north of 29541
  • Midscale hotel
  • Fitness + Health Center
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From$96 total
Very Good 4.0 /5 Read Reviews Call BookMore Details
Sleep Inn Florence North : 1833 Florence Park Dr. 1833 Florence Park Dr., Florence, SC 29501
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~10.39 miles north of 29541
  • Economy Highway hotel
  • Hotel has 2 floors
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From$70 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Florence in Florence 1912 Enterprise Dr., Florence, SC 29501
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~10.48 miles north of 29541
  • Low priced Highway property
  • Hotel has 3 floors
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From$46 total
Poor 2.5 /5 Recent Reviews Call BookMore Details
Florence Express Inn 3024 Tv Rd., Florence, SC 29501
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~12.88 miles north of 29541
  • Economy Highway property
  • Check in time: 2:00 PM
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From$72 total
Poor 2.5 /5 Read Reviews Call BookMore Details
Hilton Garden Inn Florence North I 95 : 2111 Florence Harllee Blvd. 2111 Florence Harllee Blvd., Florence, SC 29506
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~13.21 miles north of 29541
  • 3-star property
  • Check in: 3:00PM
More Photos Image of Hilton Garden Inn Florence North I 95
From$96 total
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites - Lake City 202 North Ron Mcnair Blvd., Lake City, SC 29560
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~14.32 miles south of 29541
  • Three Star hotel
  • 56 rooms in property
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From$96 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
The Inn at the Crossroads 128 West Main St., Lake City, SC 29560
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~14.65 miles south of 29541
  • Low priced Downtown hotel
  • Hotel has 6 suites
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From$130 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Lake City : 170 South Ron Mcnair Blvd. 170 South Ron Mcnair Blvd., Lake City, SC 29560
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~14.72 miles south of 29541
  • 2 star Downtown hotel
  • Complimentary breakfast is offered
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From$72 total
Average 3.5 /5 Guest Reviews Call BookMore Details

Next: Show All Available 29541 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 29541 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Florence, SC discounts available. The chart reflects the cheapest Florence hotel for each day and each star rating category.

FAQs about hotels near 29541

What are the top rated hotels near 29541?

Hotel Florence Tapestry Collection by Hilton, Comfort Inn & Suites Florence and Homewood Suites by Hilton Florence are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels near 29541?

Red Roof Inn Florence - Civic Center, Comfort Inn & Suites Florence and Fairfield Inn & Suites Florence I 20 are the top 3 luxury hotels near 29541.

What hotels are closest to the area of 29541?

Super 8 by Wyndham Florence SC I-95 North, Days Inn Florence, and Super 8 by Wyndham Florence SC I-95 North are the properties closest to 29541.

How much does a cheap hotel near 29541 cost per night?

In the last year, a 2 star hotel near 29541 can be as cheap as $72.23 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 29541 cost per night?

In the last year, the average 3 star hotel near 29541 has been $116.70 per night. (based on HotelPlanner prices)

What are the best independent hotels near 29541?

The Inn at the Crossroads, Florence Express Inn and Fairview Inn Florence are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 29541?

Residence Inn Marriott Florence, Courtyard by Marriott Florence and Fairfield Inn & Suites Florence I 20 are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 29541?

Comfort Inn & Suites Florence, Comfort Suites Florence I 95 and Quality Inn & Suites are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 29541?

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH, Staybridge Suites and Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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