Hotels in 29541 - Effingham SC

Only hotels in 29541 zip code are listed below. Search for cheap and discount hotel rates in Effingham, SC for your upcoming leisure or conference / group travel. We list the best 29541 hotels and motels so you can review the Effingham hotel list below to find the perfect lodging. Hotels in Florence county and area code 843 are also listed.

Star Rating
Hotel Name
Price Range (USD) to
Amenities
+ More

29541 Hotels/Accommodations

Super 8 by Wyndham Florence SC I-95 North / Hwy 76 3783a West Palmetto St., Florence, SC 29501
Call Us
~7.09 miles northwest of 29541
  • 2-star Highway property
  • 120 rooms in property
More Photos Image of Super 8 by Wyndham Florence SC I-95 North / Hwy 76
From$58
Not Good 1.0 /5 Latest Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 29541" Get Alexa Skill →
Days Inn Florence in Florence 3783 West Palmetto St. I 95, Florence, SC 29501
Call Us
~7.10 miles northwest of 29541
  • Two star Highway hotel
  • Free breakfast available
More Photos Image of Days Inn Florence
From$39
Poor 2.5 /5 Review Score Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76 3783a West Palmetto St., Florence, SC 29502
Call Us
~7.18 miles northwest of 29541
  • 2-star Highway hotel
  • Free complimentary breakfast
More Photos Image of Super 8 by Wyndham Florence SC I-95 North / Hwy 76
From$60
Not Good 1.0 /5 Review Score Call BookMore Details
Travelodge by Wyndham Florence in Florence 1084 Oregon Coast Highway, Florence, OR 97439
Call Us
~7.18 miles northwest of 29541
  • 2-star hotel
More Photos hotel room
From$99
Average 3.0 /5 Review Score Call BookMore Details
Comfort Inn & Suites Florence - Sc 554 527 Woody Jones Blvd., Sc 554, SC 29501
Call Us
~7.49 miles northwest of 29541
  • Mid-scale Suburban hotel
  • Check in time: 4:00 PM
More Photos Photo of Comfort Inn & Suites Florence
From$80
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites Florence I 20 501 Woody Jones Blvd., Florence, SC 29501
Call Us
~7.57 miles north of 29541
  • Mid-scale Convention Center property
  • 86 rooms in hotel
More Photos Exterior of Fairfield Inn & Suites Florence I 20
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Towneplace Suites by Marriott Florence in Florence 2650 Hospitality Blvd., Florence, SC 29501
Call Us
~7.59 miles north of 29541
  • Affordable Suburban hotel
  • Check in: 4:00 PM
More Photos Image of Towneplace Suites by Marriott Florence
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Home2 Suites by Hilton Florence, SC : 900 Woody Jones Blvd. 900 Woody Jones Blvd., Florence, SC 29501
Call Us
~7.64 miles northwest of 29541
  • Mid-scale Convention Center property
  • Hotel has an eco-friendly policy See more
More Photos Photo of Home2 Suites by Hilton Florence, SC
From$89
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Springhill Suites Florence : 2670 Hospitality Blvd. 2670 Hospitality Blvd., Florence, SC 29501
Call Us
~7.67 miles northwest of 29541
  • Midscale Convention Center property
  • Fitness + Health Center
More Photos Photo of Springhill Suites Florence
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Accident : Florence Sc Usa Florence Sc Usa, Florence, SC 29464
Call Us
~7.67 miles north of 29541
  • Mid-scale hotel
More Photos hotel room
From$307
Average 3.0 /5 Guest Reviews Call BookMore Details
Red Roof Inn Florence - Civic Center in Florence 2690 David Mcleod Blvd., Florence, SC 29501
Call Us
~7.70 miles north of 29541
  • Luxury 5-star Highway hotel
  • 112 rooms in property
More Photos Image of Red Roof Inn Florence - Civic Center
From$61
Average 3.0 /5 Reviews Call BookMore Details
Residence Inn Marriott Florence : 2660 Hospitality Blvd. 2660 Hospitality Blvd., Florence, SC 29501
Call Us
~7.72 miles northwest of 29541
  • Affordable Suburban property
  • 94 rooms in property
More Photos Exterior of Residence Inn Marriott Florence
From$94
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hotel Florence in Florence 126 West Evans St., Florence, SC 29501
Call Us
~7.77 miles north of 29541
  • Three Star Downtown hotel
  • Hotel has 5 meeting rooms
More Photos Image of Hotel Florence
From$99
Excellent 5.0 /5 Read Reviews Call BookMore Details
More Homes & Apts at Booking.com

Book online or call +1-800-219-2797

Booking for Homes and Apartments
Go to BookingGo to Booking
Hyatt Place Florence Downtown - Florence 100 East Evans St., Florence, SC 29501
Call Us
~7.78 miles north of 29541
  • 3 star Downtown hotel
  • 2 meeting rooms in hotel
More Photos Exterior of Hyatt Place Florence Downtown
From$124
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH in Florence 3440 West Radio Dr., Florence, SC 29501
Call Us
~7.83 miles northwest of 29541
  • 3-star Convention Center property
  • Check-in: 3:00 PM
More Photos Photo of Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH
From$95
Very Good 4.0 /5 Review Score Call BookMore Details
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 29541" Get Alexa Skill →
Courtyard by Marriott Florence : 2680 Hospitality Blvd. 2680 Hospitality Blvd., Florence, SC 29501
Call Us
~7.84 miles north of 29541
  • Midscale Convention Center property
  • Fitness center on property
More Photos Exterior of Courtyard by Marriott Florence
From$99
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hilton Garden Inn : 2671 Hospitality Blvd. 2671 Hospitality Blvd., Florence, SC 29501
Call Us
~7.85 miles north of 29541
  • Midscale Highway property
  • Fitness / Gym is on-site
More Photos Exterior of Hilton Garden Inn
From$109
Very Good 4.0 /5 Review Score Call BookMore Details
Staybridge Suites 150 Westpark Dr., Florence, SC 29501
Call Us
~7.86 miles northwest of 29541
  • Mid-scale Convention Center hotel
  • 112 rooms in property
More Photos Photo of Staybridge Suites
From$133
Very Good 4.0 /5 Read Reviews Call BookMore Details
Homewood Suites by Hilton Florence in Florence 3450 West Radio Dr., Florence, SC 29501
Call Us
~7.97 miles northwest of 29541
  • Affordable Convention Center property
  • Free comp. breakfast
More Photos Image of Homewood Suites by Hilton Florence
From$80
Very Good 4.5 /5 Reviews Call BookMore Details
Hampton Inn & Suites Florence Center : 3000 West Radio Dr. 3000 West Radio Dr., Florence, SC 29501
Call Us
~8.00 miles north of 29541
  • 3 star Convention Center hotel
  • Free comp. breakfast
More Photos Photo of Hampton Inn & Suites Florence Center
From$109
Very Good 4.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Florence Near Civic Center in Florence 140 Dunbarton Dr., Florence, SC 29501
Call Us
~8.10 miles northwest of 29541
  • Two star Convention Center property
  • Check in time: 3:00pm
More Photos Image of Days Inn by Wyndham Florence Near Civic Center
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites Florence Civic Center : 150 Dunbarton Dr. 150 Dunbarton Dr., Florence, SC 29501
Call Us
~8.13 miles northwest of 29541
  • Cheap Highway hotel
  • Hotel has 15 suites
More Photos Photo of Quality Inn & Suites Florence Civic Center
From$60
Average 3.0 /5 Reviews Call BookMore Details
Rodeway Inn & Suites : 181 West Lucas St. 181 West Lucas St., Florence, SC 29501
Call Us
~8.28 miles north of 29541
  • Inexpensive hotel
More Photos hotel room
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih 2101 Florence Harllee Blvd., Florence, SC 29506
Call Us
~9.08 miles north of 29541
  • Mid-scale Suburban hotel
  • Hotel has an eco-friendly policy Read more
More Photos Photo of Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih
From$94
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Best Western Inn - Florence 1808 West Lucas St., Florence, SC 29501
Call Us
~9.75 miles north of 29541
  • 2 star Highway property
  • 74 sleeping rooms in hotel
More Photos Photo of Best Western Inn
From$59
Average 3.5 /5 Hotel Reviews Call BookMore Details
Baymont Inn & Suites Florence by Wyndham : 1826 West Lucas St. 1826 West Lucas St., Florence, SC 29501
Call Us
~9.77 miles north of 29541
  • Low Cost Highway hotel
  • 2 floors in property
More Photos Exterior of Baymont Inn & Suites Florence by Wyndham
From$55
Poor 2.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Florence 1832 1 / 2 Lucas St., Florence, SC 29501
Call Us
~9.79 miles north of 29541
  • Low-priced Highway hotel
  • Check-in: 11:00 AM
More Photos Exterior of Super 8 by Wyndham Florence
From$60
Average 3.0 /5 Reviews Call BookMore Details
Knights Inn Florence in Florence 1834 West Lucas St., Florence, SC 29501
Call Us
~9.84 miles north of 29541
  • Two star hotel
More Photos Exterior of Knights Inn Florence
From$50
Poor 2.0 /5 Latest Reviews Call BookMore Details
Fairview Inn Florence in Florence 1811 West Lucas St., Florence, SC 29501
Call Us
~9.88 miles north of 29541
  • Cheap Highway property
  • 2 floors in property
More Photos Photo of Fairview Inn Florence
From$40
Poor 2.0 /5 Latest Reviews Call BookMore Details
Mainstay Suites Florence Sc : 1819 West Lucas St. Building B 1819 West Lucas St. Building B, Florence, SC 29501
Call Us
~9.99 miles north of 29541
  • Low-priced Highway property
  • Check-in: 3:00
More Photos Photo of Mainstay Suites Florence Sc
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Clarion Inn & Suites Florence - Darlington : 1819 Building a West Lucas St. 1819 Building a West Lucas St., Florence, SC 29501
Call Us
~9.99 miles north of 29541
  • 3-star Highway property
More Photos Photo of Clarion Inn & Suites Florence - Darlington
From$80
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 Florence, SC 2004 West Lucas St., Florence, SC 29501
Call Us
~10.02 miles north of 29541
  • Economical Downtown hotel
  • Check-in time: 3pm
More Photos Image of Motel 6 Florence, SC
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Park Inn by Radisson Florence Sc : 1729 Mandeville Rd. 1729 Mandeville Rd., Florence, SC 27407
Call Us
~10.05 miles north of 29541
  • 3 star property
  • 60 rooms in hotel
More Photos hotel room
From$90
Very Good 4.0 /5 Review Score Call BookMore Details
Park Inn by Radisson - Florence 1729 Mandeville Rd., Florence, SC 29501
Call Us
~10.05 miles north of 29541
  • Low-priced Highway hotel
  • Check in: 3:00 PM
More Photos Photo of Park Inn by Radisson
From$75
Average 3.0 /5 Review Score Call BookMore Details
Spark by Hilton Florence North I-95, SC - Florence 1739 Mandeville Rd., Florence, SC 29501
Call Us
~10.09 miles north of 29541
  • Mid-scale Highway property
  • 80 rooms in hotel
More Photos Exterior of Spark by Hilton Florence North I-95, SC
From$79
Very Good 4.0 /5 Review Score Call BookMore Details
Suburban Studios Florence I-95 - Florence 1914 West Lucas St., Florence, SC 29501
Call Us
~10.14 miles north of 29541
  • Low priced Highway hotel
  • 24 suites in hotel
More Photos Photo of Suburban Studios Florence I-95
From$42
Poor 2.0 /5 Review Score Call BookMore Details
Howard Johnson by Wyndham Florence in Florence 2038 West Lucas St., Florence, SC 29501
Call Us
~10.15 miles north of 29541
  • Economical Highway property
  • Check in: 3:00PM
More Photos Image of Howard Johnson by Wyndham Florence
From$60
Poor 2.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Florence North I 95 in Florence 1735 Stokes Rd., Florence, SC 29501
Call Us
~10.16 miles north of 29541
  • Low priced Highway property
  • Free breakfast available
More Photos Exterior of Hampton Inn & Suites Florence North I 95
From$104
Very Good 4.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Florence/I-95 North 2111 West Lucas, Florence, SC 29501
Call Us
~10.27 miles north of 29541
  • Inexpensive Highway property
  • 103 rooms in hotel
More Photos Image of Days Inn by Wyndham Florence/I-95 North
From$50
Average 3.5 /5 Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Florence : 2123 West Lucas St. 2123 West Lucas St., Florence, SC 29501
Call Us
~10.27 miles north of 29541
  • Three Star Highway property
  • Check in time: 2:00 pm
More Photos Photo of La Quinta Inn & Suites by Wyndham Florence
From$82
Very Good 4.0 /5 Review Score Call BookMore Details
Comfort Suites Florence I 95 2120 West Lucas St., Florence, SC 29501
Call Us
~10.31 miles north of 29541
  • Midscale Highway hotel
  • Hotel has 77 rooms
More Photos Photo of Comfort Suites Florence I 95
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Tru by Hilton Florence I-95 in Florence 2140 West Lucas St., Florence, SC 29501
Call Us
~10.36 miles north of 29541
  • 3 star hotel
  • 5 floors in hotel
More Photos Exterior of Tru by Hilton Florence I-95
From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Sleep Inn Florence North : 1833 Florence Park Dr. 1833 Florence Park Dr., Florence, SC 29501
Call Us
~10.39 miles north of 29541
  • 2-star Highway hotel
  • Check-in: 3:00pm
More Photos Photo of Sleep Inn Florence North
From$59
Average 3.0 /5 Guest Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Florence : 1912 Enterprise Dr. 1912 Enterprise Dr., Florence, SC 29501
Call Us
~10.48 miles north of 29541
  • Economical Highway hotel
  • 3 floors in property
More Photos Photo of Microtel Inn & Suites by Wyndham Florence
From$39
Poor 2.5 /5 Hotel Reviews Call BookMore Details
Florence Express Inn in Florence 3024 Tv Rd., Florence, SC 29501
Call Us
~12.88 miles north of 29541
  • Two-star Highway property
  • Check in time: 2:00 PM
More Photos Exterior of Florence Express Inn
From$60
Poor 2.5 /5 Latest Reviews Call BookMore Details
Hilton Garden Inn Florence North I 95 in Florence 2111 Florence Harllee Blvd., Florence, SC 29506
Call Us
~13.21 miles north of 29541
  • Midscale hotel
  • 12 suites in property
More Photos Photo of Hilton Garden Inn Florence North I 95
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites in Lake City 202 North Ron Mcnair Blvd., Lake City, SC 29560
Call Us
~14.32 miles south of 29541
  • 3 star hotel
  • 56 rooms in property
More Photos Image of Quality Inn & Suites
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Inn at the Crossroads - Lake City 128 West Main St., Lake City, SC 29560
Call Us
~14.65 miles south of 29541
  • Inexpensive Downtown property
  • Hotel has 6 suites
More Photos Image of Inn at the Crossroads
From$109
Very Good 4.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Lake City 170 South Ron Mcnair Blvd., Lake City, SC 29560
Call Us
~14.72 miles south of 29541
  • 2 star Downtown hotel
  • Check in time: 02.00 PM
More Photos Image of Days Inn by Wyndham Lake City
From$60
Average 3.5 /5 Reviews Call BookMore Details
Days Inn by Wyndham Turbeville : 7835 Myrtle Beach Highway 7835 Myrtle Beach Highway, Gable, SC 29051
Call Us
~21.82 miles southwest of 29541
  • Low priced property
More Photos Exterior of Days Inn by Wyndham Turbeville
From$60
Poor 2.0 /5 Read Reviews Call BookMore Details

Next: Show All Available 29541 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 29541 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Florence, SC discounts available. The chart reflects the cheapest Florence hotel for each day and each star rating category.

FAQs about hotels near 29541

What are the top rated hotels near 29541?

Hotel Florence, Comfort Inn & Suites Florence and Homewood Suites by Hilton Florence are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels near 29541?

Red Roof Inn Florence - Civic Center, Comfort Inn & Suites Florence and Fairfield Inn & Suites Florence I 20 are the top 3 luxury hotels near 29541.

What hotels are closest to the area of 29541?

Super 8 by Wyndham Florence SC I-95 North, Days Inn Florence, and Super 8 by Wyndham Florence SC I-95 North are the properties closest to 29541.

How much does a cheap hotel near 29541 cost per night?

In the last year, a 2 star hotel near 29541 can be as cheap as $67.04 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 29541 cost per night?

In the last year, the average 3 star hotel near 29541 has been $115.40 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 29541?

Hotel Florence, Inn at the Crossroads and Florence Express Inn are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 29541?

Residence Inn Marriott Florence, Courtyard by Marriott Florence and Fairfield Inn & Suites Florence I 20 are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 29541?

Comfort Inn & Suites Florence, Comfort Suites Florence I 95 and Quality Inn & Suites are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 29541?

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH, Staybridge Suites and Holiday Inn Express Hotel & Suites Florence I 95 at Hwy 327 by Ih are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Back to Top