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78543 Hotels, Motels & Accommodations

Motel 6 Weslaco, TX
+1-888-389-4121
1024 West Expressway 83, Weslaco, TX 78596 ~8.74 miles south of 78543
  • Inexpensive hotel
  • 3 floors in property
From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
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Super 8 by Wyndham Weslaco
+1-888-675-2083
1702 East Expressway 83, Weslaco, TX 78596 ~8.93 miles south of 78543
  • Economy Highway property
  • 2 floors in property
From$35
Average 3.5 /5 Recent Reviews Call BookMore Details
Victoria Palms Inn & Suites in Donna
+1-800-716-8490
600 Kingston Way, Donna, TX 78537 ~8.94 miles south of 78543
  • 3-star Resort property
  • Hotel has 120 rooms
From$44
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Weslaco
+1-800-805-5223
1004 Fairfield Blvd., Weslaco, TX 78596 ~9.00 miles south of 78543
  • Midscale property
  • Fitness + Health Center
From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Best Western Town Center Inn
+1-888-965-1860
1005 Fairfield Blvd., Weslaco, TX 78596 ~9.02 miles south of 78543
  • Affordable Highway property
  • Comp. Breakfast
From$51
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Express Inn : 3021 East Expressway 83
+1-888-788-5576
3021 East Expressway 83, Weslaco, TX 78596 ~9.34 miles south of 78543
  • 2 star property
  • Free complimentary breakfast
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn & Suites Donna near I-2 in Donna
+1-888-897-9207
495 West Expressway 83, Donna, TX 78537 ~9.48 miles southwest of 78543
  • Low Cost Highway hotel
  • Hotel has 55 rooms
From$65
Very Good 4.0 /5 Review Score Call BookMore Details
La Copa Inn in Alamo
+1-888-311-4278
714 North Tower Rd., Alamo, TX 78516 ~9.62 miles southwest of 78543
  • Low-priced property
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Palm Aire Hotel and Suites : 415 South International Blvd.
+1-888-469-4795
415 South International Blvd., Weslaco, TX 78596 ~9.78 miles south of 78543
  • 3 star Resort hotel
  • Free comp. breakfast
From$45
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Weslaco by IHG - Weslaco
+1-888-734-9421
421 South International Blvd., Weslaco, TX 78596 ~9.84 miles south of 78543
  • 3 star Suburban hotel
  • Comp. Breakfast
From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Weslaco Inn in Weslaco
+1-888-841-5292
2716 East Business 83, Weslaco, TX 78596 ~10.02 miles south of 78543
  • Economical Highway property
  • Check-in: 02:00 pm
From$40
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Texas Inn and Suites City Center at University Dr.
+1-888-455-5160
202 North Highway 281 Exit University Dr., Edinburg, TX 78541 ~10.09 miles west of 78543
  • Cheap Downtown property
  • Check in time: 1:00pm
From$34
Average 3.5 /5 Latest Reviews Call BookMore Details
Texas Inn & Suites Rgv
+1-888-965-8297
1210 East Canton Rd., Edinburg, TX 78539 ~10.79 miles west of 78543
  • Two star Downtown property
  • Hotel has 2 floors
From$60
Average 3.0 /5 Reviews Call BookMore Details
Texas Inn and Suites City Center at University Dr. - Edinburg
+1-888-906-6358
202 North 25th Ave., Edinburg, TX 78539 ~11.09 miles west of 78543
  • Cheap hotel
  • Check-in: 11:00 AM
Quality Inn & Suites at The Outlets Mercedes/Weslaco
+1-888-749-6785
4701 East Expressway 83, Mercedes, TX 78570 ~11.15 miles southeast of 78543
  • 3-star property
  • Check-in time: 3:00 pm
From$52
Very Good 4.0 /5 Reviews Call BookMore Details
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La Quinta Inn & Suites by Wyndham Alamo Mcallen East - Alamo
+1-888-878-9982
909 East Frontage Rd., Alamo, TX 78516 ~11.30 miles southwest of 78543
  • 3-star Highway property
  • 3 suites in hotel
From$69
Very Good 4.0 /5 Reviews Call BookMore Details
Motel 6 Edinburg Tx
+1-888-389-4485
1806 Closner Blvd., Edinburg, TX 78539 ~11.33 miles west of 78543
  • Economy property
  • Check in time: 1:00pm
From$44
Average 3.0 /5 Latest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Mercedes Outlet Mall - Mercedes
+1-888-389-4121
7007 East Expressway 83, Mercedes, TX 78570 ~11.47 miles southeast of 78543
  • 3 star Highway property
  • Complimentary breakfast is offered
From$69
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Best Western Plus Edinburg Inn & Suites in Edinburg
+1-888-675-2083
2708 South Us Highway 281 (Closner Blvd), Edinburg, TX 78539 ~11.62 miles west of 78543
  • Three Star Suburban hotel
  • Hotel has 56 rooms
From$51
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn Edinburg South - Edinburg
+1-800-716-8490
4001 Closner, Edinburg, TX 78539 ~11.96 miles west of 78543
  • Three Star Highway property
  • Check in time: 1:00 pm
From$60
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
MainStay Suites Edinburg South : 4001 South Us Highway 281
+1-800-805-5223
4001 South Us Highway 281, Edinburg, TX 78539 ~11.97 miles west of 78543
  • Cheap Highway property
  • Check in: 3:00 PM
From$60
Very Good 4.0 /5 Reviews Call BookMore Details
Comfort Inn - Edinburg
+1-888-965-1860
4001 South Closner Blvd., Edinburg, TX 78539 ~11.99 miles west of 78543
  • 3-star hotel
  • 3 floors in property
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Edinburg-McAllen Area by IHG
+1-888-788-5576
3801 South Business Highway 281, Edinburg, TX 78539 ~12.07 miles west of 78543
  • Midscale Downtown hotel
  • 18 suites in property
From$77
Very Good 4.0 /5 Review Score Call BookMore Details
TRU by Hilton Edinburg : 407 West Trenton Rd.
+1-888-897-9207
407 West Trenton Rd., Edinburg, TX 78539 ~12.13 miles west of 78543
  • Mid-scale Suburban property
  • Check in: 3:00pm
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Home2 Suites by Hilton Edinburg - Edinburg
+1-888-311-4278
411 West Trenton, Edinburg, TX 78539 ~12.15 miles west of 78543
  • 3-star property
  • 14 sleeping rooms in hotel
From$90
Very Good 4.0 /5 Review Score Call BookMore Details
Towneplace Suites by Marriott Mcallen Edinburg
+1-888-469-4795
502 West Trenton Rd., Edinburg, TX 78539 ~12.27 miles west of 78543
  • Three Star Suburban property
  • 95 rooms in property
From$79
Very Good 4.0 /5 Review Score Call BookMore Details
Rodeway Inn San Juan : 112 West Expressway 83
+1-888-734-9421
112 West Expressway 83, San Juan, TX 78589 ~12.62 miles southwest of 78543
  • 2-star hotel
  • Check in time: 2:00pm
From$38
Average 3.0 /5 Latest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Pharr RGV Medical Center : 4603 North Cage
+1-888-841-5292
4603 North Cage, Pharr, TX 78577 ~12.71 miles west of 78543
  • Midscale Highway hotel
  • 30 suites in hotel
From$65
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Motel 6 Pharr, TX : 4701 North Cage
+1-888-455-5160
4701 North Cage, Pharr, TX 78577 ~12.75 miles west of 78543
  • Low-priced hotel
  • Hotel has 110 rooms
From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Pharr North Mcallen
+1-888-965-8297
4607 North Cage Blvd., Pharr, TX 78577 ~12.83 miles west of 78543
  • Three Star Highway property
  • Check-in: 3:00 pm
From$62
Very Good 4.0 /5 Reviews Call BookMore Details
Red Roof Inn Pharr - McAllen
+1-888-906-6358
4401 North Cage Blvd., Pharr, TX 78577 ~12.92 miles west of 78543
  • Two-star hotel
  • Hotel has 2 floors
From$60
Very Good 4.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Pharr in Pharr
+1-888-749-6785
300 West Nolana Loop, Pharr, TX 78577 ~12.97 miles west of 78543
  • Mid-scale Rural hotel
  • Fitness + Health Center
From$67
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Texas Inn & Suites
+1-888-878-9982
1130 East Expressway 83, Pharr, TX 78577 ~13.18 miles southwest of 78543
  • Two-star Highway property
  • 2 floors in property
From$46
Average 3.5 /5 Reviews Call BookMore Details
Comfort Inn & Suites Pharr - McAllen
+1-888-389-4485
2706 North Cage Blvd., Pharr, TX 78577 ~13.40 miles west of 78543
  • Economical Airport hotel
  • Shuttle to airport available
From$58
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Woodspring Suites Pharr : 1207 West Expressway 83
+1-888-389-4121
1207 West Expressway 83, Pharr, TX 78577 ~14.69 miles west of 78543
  • 2 star Suburban hotel
  • Check-in time: 3:00 p.m.
From$35
Very Good 4.0 /5 Review Score Call BookMore Details
Americas Best Value Inn Pharr - Pharr
+1-888-675-2083
1301 West Expressway 83, Pharr, TX 78577 ~15.06 miles west of 78543
  • 2-star Airport hotel
  • 2 floors in property
From$47
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Pharr by IHG in Pharr
+1-800-716-8490
205 West Nolana Loop, Pharr, TX 78577 ~15.18 miles southwest of 78543
  • Midscale Highway hotel
  • 2 conference rooms in property
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Texas Inn Downtown Mcallen
+1-800-805-5223
1420 East Jackson Ave., Mcallen, TX 78503 ~15.73 miles west of 78543
  • Mid-scale Downtown property
  • 2 floors in property
From$40
Average 3.0 /5 Read Reviews Call BookMore Details
Motel 6 McAllen, TX - East
+1-888-965-1860
801 East Expressway 83, Mcallen, TX 78501 ~16.09 miles west of 78543
  • Cheap hotel
  • Hotel has 3 floors
From$60
Average 3.5 /5 Hotel Reviews Call BookMore Details
Best Western McAllen Medical Center
+1-888-788-5576
300 East Expressway 83, Mcallen, TX 78503 ~16.52 miles west of 78543
  • Affordable property
  • 23 suites in hotel
From$51
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Mcallen : 10 West Expressway 83
+1-888-897-9207
10 West Expressway 83, Mcallen, TX 78503 ~16.66 miles west of 78543
  • Midscale Airport property
  • Hotel has 5 floors
From$58
Very Good 4.0 /5 Review Score Call BookMore Details
Residence Inn by Marriott Mcallen - Mcallen
+1-888-311-4278
220 West Expressway 83 (I 2), Mcallen, TX 78501 ~16.81 miles west of 78543
  • Midscale Airport hotel
  • Shuttle to airport available
From$69
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Pear Tree Inn Mcallen in Mcallen
+1-888-469-4795
Pear Tree Inn Mcallen, Mcallen, TX 78501 ~16.86 miles west of 78543
  • Affordable Suburban hotel
  • 91 sleeping rooms in hotel
From$54
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Casa De Palmas Trademark Collection by Wyndham in Mcallen
+1-888-734-9421
101 North Main St., Mcallen, TX 78501 ~16.87 miles west of 78543
  • 3-star Downtown property
  • 165 sleeping rooms in hotel
From$79
Average 3.0 /5 Reviews Call BookMore Details
DoubleTree Suites by Hilton Hotel McAllen
+1-888-841-5292
1800 South 2nd St., Mcallen, TX 78503 ~16.92 miles west of 78543
  • Four star Downtown property
  • Check-in: 3:00PM
From$84
Very Good 4.0 /5 Recent Reviews Call BookMore Details
La Copa Inn McAllen
+1-888-455-5160
1010 West Houston Ave., Mcallen, TX 78501 ~16.97 miles west of 78543
  • Low Cost hotel
  • Check in: 3:00 PM
Holiday Inn Mcallen – Medical Center Area : 612 West Expressway 83
+1-888-965-8297
612 West Expressway 83, Mcallen, TX 78501 ~16.98 miles west of 78543
  • 3-star Suburban hotel
  • Check-in time: 3:00 PM
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Baymont Inn & Suites by Wyndham
+1-888-906-6358
620 West Expressway 83 Hotel Baymont Inn, Mcallen, TX 78501 ~17.00 miles west of 78543
  • 3 star Highway property
  • Check-in: 3:00 P.M
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Mcallen
+1-888-749-6785
620 West Expy 83, Mcallen, TX 78501 ~17.00 miles west of 78543
  • Affordable Highway property
  • Fitness + Health Center
OYO Hotel McAllen Airport South - Mcallen
+1-888-878-9982
1301 South 9th St., Mcallen, TX 78501 ~17.01 miles west of 78543
  • Midscale Airport property
  • Hotel has a green policy See more

Next: Show All Available 78543 Hotels with Pricing

Graph of Weslaco, TX Hotel Prices for Next 20 Days

Rates shown are nightly rates before taxes and do not necessarily reflect all Weslaco, TX discounts available. The chart reflects the cheapest Weslaco hotel for each day and each star rating category.

FAQs about hotels near 78543

What are the best rated hotels near 78543?

Comfort Inn Edinburg South, Motel 6 Weslaco, TX and Victoria Palms Inn & Suites are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels near 78543?

DoubleTree Suites by Hilton Hotel McAllen, Victoria Palms Inn & Suites and Hampton Inn Weslaco are the top 3 luxury hotels near 78543.

What hotels are closest to the area of 78543?

Motel 6 Weslaco, TX, Super 8 by Wyndham Weslaco, and Victoria Palms Inn & Suites are the properties closest to 78543.

How much does a cheap hotel near 78543 cost per night?

In the last year, a 2 star hotel near 78543 can be as cheap as $55.11 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 78543 cost per night?

In the last year, the average 3 star hotel near 78543 has been $79.95 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 78543?

Victoria Palms Inn & Suites, Palm Aire Hotel and Suites and Weslaco Inn are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 78543?

Towneplace Suites by Marriott Mcallen Edinburg, Residence Inn by Marriott Mcallen and Casa De Palmas Trademark Collection by Wyndham are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 78543?

Comfort Inn Edinburg South, Comfort Inn & Suites Donna near I-2 and Quality Inn & Suites at The Outlets Mercedes are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular Best Western hotels near 78543?

Best Western Town Center Inn, Best Western Plus Edinburg Inn & Suites and Best Western McAllen Medical Center are the best rated Best Western branded hotels (based on user reviews score).

What are the best IHG hotels near 78543?

Holiday Inn Express Hotel & Suites Weslaco by IHG, Holiday Inn Express & Suites Edinburg-McAllen Area by IHG and Holiday Inn Express Hotel & Suites Pharr by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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