Star Rating
Hotel Name
Price Range (USD) to
Amenities
+ More

78543 Hotels, Motels & Accommodations

Motel 6 Weslaco, TX 1024 West Expressway 83, Weslaco, TX 78596 ~8.74 miles south of 78543
  • Economical hotel
  • Check in: 15:00
From$60
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 78543" Get Alexa Skill →
Super 8 by Wyndham Weslaco in Weslaco 1702 East Expressway 83, Weslaco, TX 78596 ~8.93 miles south of 78543
  • Inexpensive Highway property
  • Hotel has 4 suites
From$35
Average 3.5 /5 Hotel Reviews Call BookMore Details
Victoria Palms Inn & Suites 600 Kingston Way, Donna, TX 78537 ~8.94 miles south of 78543
  • Mid-scale Resort hotel
  • Hotel has an eco-friendly policy See policy
From$44
Very Good 4.0 /5 Reviews Call BookMore Details
Hampton Inn Weslaco in Weslaco 1004 Fairfield Blvd., Weslaco, TX 78596 ~9.00 miles south of 78543
  • Three Star hotel
  • Check in: 15:00
From$90
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Best Western Town Center Inn in Weslaco 1005 Fairfield Blvd., Weslaco, TX 78596 ~9.02 miles south of 78543
  • Three Star Highway hotel
  • Hotel has 3 floors
From$52
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Express Inn 3021 East Expressway 83, Weslaco, TX 78596 ~9.34 miles south of 78543
  • Low Cost hotel
  • Free comp. breakfast
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn & Suites Donna near I-2 495 West Expressway 83, Donna, TX 78537 ~9.48 miles southwest of 78543
  • Economical Highway hotel
  • Comp. Breakfast
From$65
Very Good 4.0 /5 Reviews Call BookMore Details
La Copa Inn : 714 North Tower Rd. 714 North Tower Rd., Alamo, TX 78516 ~9.62 miles southwest of 78543
  • 2-star property
  • Check in: 2:00
From$60
Average 3.0 /5 Reviews Call BookMore Details
Palm Aire Hotel and Suites - Weslaco 415 South International Blvd., Weslaco, TX 78596 ~9.78 miles south of 78543
  • Mid-scale Resort property
  • 5 conference rooms in property
From$45
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express Hotel & Suites Weslaco by IHG 421 South International Blvd., Weslaco, TX 78596 ~9.84 miles south of 78543
  • Midscale Suburban hotel
  • 3 floors in hotel
From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Weslaco Inn by Capital O Near Mercedes 2716 East Business 83, Weslaco, TX 78596 ~10.02 miles south of 78543
  • Economical Highway hotel
  • Hotel has 2 floors
From$40
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Texas Inn and Suites City Center at University Dr. 202 North Highway 281 Exit University Dr., Edinburg, TX 78541 ~10.09 miles west of 78543
  • Cheap Downtown property
  • 51 rooms in hotel
From$34
Average 3.5 /5 Read Reviews Call BookMore Details
Texas Inn & Suites Rgv 1210 East Canton Rd., Edinburg, TX 78539 ~10.79 miles west of 78543
  • Cheap Downtown hotel
  • Check-in time: 1:00PM
From$60
Average 3.0 /5 Reviews Call BookMore Details
Texas Inn and Suites City Center at University Dr. in Edinburg 202 North 25th Ave., Edinburg, TX 78539 ~11.09 miles west of 78543
  • Two star property
  • Check in time: 11:00 AM
Quality Inn & Suites at The Outlets Mercedes/Weslaco - Mercedes 4701 East Expressway 83, Mercedes, TX 78570 ~11.15 miles southeast of 78543
  • 3-star property
  • Check-in: 3:00 pm
From$52
Very Good 4.0 /5 Reviews Call BookMore Details
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 78543" Get Alexa Skill →
La Quinta Inn & Suites by Wyndham Alamo Mcallen East : 909 East Frontage Rd. 909 East Frontage Rd., Alamo, TX 78516 ~11.30 miles southwest of 78543
  • 3-star Highway property
  • Gym / Fitness Center Available
From$69
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Edinburg Tx - Edinburg 1806 Closner Blvd., Edinburg, TX 78539 ~11.33 miles west of 78543
  • Low priced property
  • 49 sleeping rooms in hotel
From$44
Average 3.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham Mercedes Outlet Mall - Mercedes 7007 East Expressway 83, Mercedes, TX 78570 ~11.47 miles southeast of 78543
  • Midscale Highway property
  • Check in time: 2:00pm
From$69
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Best Western Plus Edinburg Inn & Suites in Edinburg 2708 South Us Highway 281 (Closner Blvd), Edinburg, TX 78539 ~11.62 miles west of 78543
  • 3 star Suburban property
  • 56 rooms in hotel
From$52
Very Good 4.0 /5 Read Reviews Call BookMore Details
Comfort Inn Edinburg South 4001 Closner, Edinburg, TX 78539 ~11.96 miles west of 78543
  • Affordable Highway property
  • Hotel has 2 meeting rooms
From$60
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
MainStay Suites Edinburg South : 4001 South Us Highway 281 4001 South Us Highway 281, Edinburg, TX 78539 ~11.97 miles west of 78543
  • Inexpensive Highway hotel
  • 48 sleeping rooms in hotel
From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Inn 4001 South Closner Blvd., Edinburg, TX 78539 ~11.99 miles west of 78543
  • Mid-scale property
  • 3 floors in property
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Edinburg-McAllen Area by IHG - Edinburg 3801 South Business Highway 281, Edinburg, TX 78539 ~12.07 miles west of 78543
  • 3 star Downtown hotel
  • 18 suites in property
From$77
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
TRU by Hilton Edinburg 407 West Trenton Rd., Edinburg, TX 78539 ~12.13 miles west of 78543
  • 3 star Suburban property
  • Check in: 3:00pm
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Home2 Suites by Hilton Edinburg 411 West Trenton, Edinburg, TX 78539 ~12.15 miles west of 78543
  • 3 star property
  • 14 sleeping rooms in hotel
From$90
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Towneplace Suites by Marriott Mcallen Edinburg : 502 West Trenton Rd. 502 West Trenton Rd., Edinburg, TX 78539 ~12.27 miles west of 78543
  • Midscale Suburban hotel
  • 4 floors in property
From$79
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Rodeway Inn San Juan 112 West Expressway 83, San Juan, TX 78589 ~12.62 miles southwest of 78543
  • Economical hotel
  • 82 sleeping rooms in hotel
From$38
Average 3.0 /5 Hotel Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Pharr RGV Medical Center 4603 North Cage, Pharr, TX 78577 ~12.71 miles west of 78543
  • Mid-scale Highway property
  • Complimentary breakfast is offered
From$65
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Motel 6 Pharr, TX : 4701 North Cage 4701 North Cage, Pharr, TX 78577 ~12.75 miles west of 78543
  • Two-star property
  • 110 rooms in hotel
From$60
Very Good 4.0 /5 Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Pharr North Mcallen : 4607 North Cage Blvd. 4607 North Cage Blvd., Pharr, TX 78577 ~12.83 miles west of 78543
  • 3 star Highway property
  • 67 rooms in property
From$62
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn Pharr - McAllen : 4401 North Cage Blvd. 4401 North Cage Blvd., Pharr, TX 78577 ~12.92 miles west of 78543
  • Low priced hotel
  • Check-in time: 15:00
From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Pharr : 300 West Nolana Loop 300 West Nolana Loop, Pharr, TX 78577 ~12.97 miles west of 78543
  • Affordable Rural property
  • Fitness center on property
From$67
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Texas Inn & Suites - Pharr 1130 East Expressway 83, Pharr, TX 78577 ~13.18 miles southwest of 78543
  • Low Cost Highway property
  • Free comp. breakfast
From$46
Average 3.5 /5 Reviews Call BookMore Details
Comfort Inn & Suites Pharr - McAllen - Pharr 2706 North Cage Blvd., Pharr, TX 78577 ~13.40 miles west of 78543
  • Two star Airport property
  • 71 rooms in property
From$58
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Woodspring Suites Pharr - Pharr 1207 West Expressway 83, Pharr, TX 78577 ~14.69 miles west of 78543
  • 2-star Suburban hotel
  • 4 floors in hotel
From$35
Very Good 4.0 /5 Reviews Call BookMore Details
Americas Best Value Inn Pharr - Pharr 1301 West Expressway 83, Pharr, TX 78577 ~15.06 miles west of 78543
  • 2-star Airport hotel
  • 58 rooms in property
From$47
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express Hotel & Suites Pharr by IHG in Pharr 205 West Nolana Loop, Pharr, TX 78577 ~15.18 miles southwest of 78543
  • Midscale Highway property
  • Free breakfast available
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Texas Inn Downtown Mcallen - Mcallen 1420 East Jackson Ave., Mcallen, TX 78503 ~15.73 miles west of 78543
  • Mid-scale Downtown property
  • Hotel has 40 rooms
From$40
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 McAllen, TX - East 801 East Expressway 83, Mcallen, TX 78501 ~16.09 miles west of 78543
  • Cheap property
  • Hotel has 3 floors
From$60
Average 3.5 /5 Latest Reviews Call BookMore Details
Best Western McAllen Medical Center 300 East Expressway 83, Mcallen, TX 78503 ~16.52 miles west of 78543
  • Midscale property
  • Free breakfast available
From$52
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Mcallen 10 West Expressway 83, Mcallen, TX 78503 ~16.66 miles west of 78543
  • Three Star Airport property
  • Check in: 3pm
From$58
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Residence Inn by Marriott Mcallen 220 West Expressway 83 (I 2), Mcallen, TX 78501 ~16.81 miles west of 78543
  • Midscale Airport hotel
  • 3 floors in property
From$69
Very Good 4.0 /5 Reviews Call BookMore Details
Pear Tree Inn Mcallen in Mcallen Pear Tree Inn Mcallen, Mcallen, TX 78501 ~16.86 miles west of 78543
  • 3 star Suburban hotel
  • 91 sleeping rooms in hotel
From$54
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Casa De Palmas Trademark Collection by Wyndham 101 North Main St., Mcallen, TX 78501 ~16.87 miles west of 78543
  • Midscale Downtown hotel
  • 10 meeting rooms in hotel
From$79
Average 3.0 /5 Hotel Reviews Call BookMore Details
Drury Inn & Suites Mcallen in Mcallen 300 West Expressway 83, Mcallen, TX 78501 ~16.87 miles west of 78543
  • Midscale Convention Center hotel
  • 6 floors in hotel
From$94
Very Good 4.5 /5 Reviews Call BookMore Details
DoubleTree Suites by Hilton Hotel McAllen 1800 South 2nd St., Mcallen, TX 78503 ~16.92 miles west of 78543
  • 4 star Downtown hotel
  • Gym is available on property
From$84
Very Good 4.0 /5 Read Reviews Call BookMore Details
La Copa Inn McAllen : 1010 West Houston Ave. 1010 West Houston Ave., Mcallen, TX 78501 ~16.97 miles west of 78543
  • Low-priced property
Holiday Inn Mcallen – Medical Center Area : 612 West Expressway 83 612 West Expressway 83, Mcallen, TX 78501 ~16.98 miles west of 78543
  • Mid-scale Suburban hotel
  • 89 rooms in property
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Baymont Inn & Suites by Wyndham 620 West Expressway 83 Hotel Baymont Inn, Mcallen, TX 78501 ~17.00 miles west of 78543
  • 3-star Highway hotel
  • Hotel has 3 floors
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Baymont by Wyndham Mcallen 620 West Expy 83, Mcallen, TX 78501 ~17.00 miles west of 78543
  • Midscale Highway property
  • Complimentary breakfast is offered

Next: Show All Available 78543 Hotels with Pricing

Graph of Weslaco, TX Hotel Prices for Next 20 Days

Rates shown are nightly rates before taxes and do not necessarily reflect all Weslaco, TX discounts available. The chart reflects the cheapest Weslaco hotel for each day and each star rating category.

FAQs about hotels near 78543

What are the best rated hotels near 78543?

Comfort Inn Edinburg South, Drury Inn & Suites Mcallen and Motel 6 Weslaco, TX are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels near 78543?

DoubleTree Suites by Hilton Hotel McAllen, Victoria Palms Inn & Suites and Hampton Inn Weslaco are the top 3 luxury hotels near 78543.

What hotels are closest to the area of 78543?

Motel 6 Weslaco, TX, Super 8 by Wyndham Weslaco, and Victoria Palms Inn & Suites are the properties closest to 78543.

How much does a cheap hotel near 78543 cost per night?

In the last year, a 2 star hotel near 78543 can be as cheap as $57.63 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 78543 cost per night?

In the last year, the average 3 star hotel near 78543 has been $83.82 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 78543?

Victoria Palms Inn & Suites, Palm Aire Hotel and Suites and Weslaco Inn by Capital O Near Mercedes are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 78543?

Towneplace Suites by Marriott Mcallen Edinburg, Residence Inn by Marriott Mcallen and Casa De Palmas Trademark Collection by Wyndham are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 78543?

Comfort Inn Edinburg South, Comfort Inn & Suites Donna near I-2 and Quality Inn & Suites at The Outlets Mercedes are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular Best Western hotels near 78543?

Best Western Town Center Inn, Best Western Plus Edinburg Inn & Suites and Best Western McAllen Medical Center are the best rated Best Western branded hotels (based on user reviews score).

What are the best IHG hotels near 78543?

Holiday Inn Express Hotel & Suites Weslaco by IHG, Holiday Inn Express & Suites Edinburg-McAllen Area by IHG and Holiday Inn Express Hotel & Suites Pharr by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Back to Top