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45646 Hotels/Motels & Accommodations

Quality Inn Seaman - Seaman
+1-888-389-4121
55 Stern Dr., Seaman, OH 45679 ~15.81 miles southwest of 45646
  • Cheap hotel
  • Check-in: 14:00
From$79
Very good 4.0 /5 Review Score Call BookMore Details
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Greystone Motel
+1-888-675-2083
8190 Us Highway 50, Hillsboro, OH 45133 ~16.55 miles northwest of 45646
  • Inexpensive Downtown property
  • 36 rooms in property
From$50
Very good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn in Piketon
+1-800-716-8490
7525 Us 23, Piketon, OH 45661 ~17.06 miles east of 45646
  • Three Star Lake hotel
  • Check-in time: 12:00
From$80
Very good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Hillsboro in Hillsboro
+1-800-805-5223
103 Harry Sauner Rd., Hillsboro, OH 45133 ~18.59 miles northwest of 45646
  • Inexpensive hotel
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Shawnee Lodge & Conference Center : 4404b State Route 125
+1-888-965-1860
4404b State Route 125, West Portsmouth, OH 45663 ~23.69 miles south of 45646
  • Mid-scale Rural property
  • 50 sleeping rooms in hotel
From$59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites in Portsmouth
+1-888-788-5576
5100 Scioto Trail, Portsmouth, OH 45662 Website ~26.47 miles southeast of 45646
  • Two-star hotel
  • Check-in time: 3:00 PM
From$60
Very good 4.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Portsmouth
+1-888-897-9207
4266 Us Route 23 North, Portsmouth, OH 45622 ~26.76 miles southeast of 45646
  • Cheap Rural property
  • 4 suites in hotel
From$54
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Chillicothe : 100 North Plaza Blvd.
+1-888-311-4278
100 North Plaza Blvd., Chillicothe, OH 45601 ~27.14 miles northeast of 45646
  • Mid-scale Rural hotel
  • Fitness / Gym is on-site
From$135
Very good 4.0 /5 Latest Reviews Call BookMore Details
Rodeway Inn & Suites : 3762 Us Highway 23
+1-888-469-4795
3762 Us Highway 23, Portsmouth, OH 45662 ~27.16 miles southeast of 45646
  • Low-priced property
  • Free complimentary breakfast
From$36
Poor 2.0 /5 Reviews Call BookMore Details
Quality Inn
+1-888-734-9421
20 North Plaza Blvd., Chillicothe, OH 45601 ~27.17 miles northeast of 45646
  • Midscale Highway property
  • Fitness + Health Center
From$80
Very good 4.0 /5 Read Reviews Call BookMore Details
Fairfield Inn and Suites by Marriott Chillicothe : 300 North Plaza Blvd.
+1-888-841-5292
300 North Plaza Blvd., Chillicothe, OH 45601 ~27.21 miles northeast of 45646
  • Three Star hotel
  • 81 sleeping rooms in hotel
From$125
Very good 4.0 /5 Read Reviews Call BookMore Details
Christopher Inn and Suites
+1-888-455-5160
30 North Plaza Blvd., Chillicothe, OH 45601 ~27.21 miles northeast of 45646
  • 3-star Highway property
  • 2 floors in property
From$85
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Chillicothe East by IHG - Chillicothe
+1-888-965-8297
1003 East Main St., Chillicothe, OH 45601 ~27.52 miles northeast of 45646
  • Midscale Suburban hotel
  • Free breakfast
From$87
Very good 4.0 /5 Guest Reviews Call BookMore Details
Americas Best Value Inn Chillicothe
+1-888-906-6358
1135 East Main St., Chillicothe, OH 45601 ~27.63 miles northeast of 45646
  • Economical Highway property
  • Free comp. breakfast
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Best Western Adena Inn : 1250 North Bridge St.
+1-888-749-6785
1250 North Bridge St., Chillicothe, OH 45601 ~27.65 miles northeast of 45646
  • Two star Downtown hotel
  • Free breakfast available
From$92
Very good 4.0 /5 Hotel Reviews Call BookMore Details
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Holiday Inn Portsmouth Downtown, an IHG Hotel - Portsmouth
+1-888-878-9982
711 2nd St., Portsmouth, OH 45662 ~29.34 miles southeast of 45646
  • Three Star Downtown property
  • Hotel has 88 rooms
From$107
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Countryside Inn & Suites in Mount Orab
+1-888-389-4485
100 Leininger St., Mount Orab, OH 45154 ~31.45 miles west of 45646
  • Three Star Rural property
  • 50 rooms in property
From$85
Very good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Washington Court House by IHG in Washington Court House
+1-888-389-4121
101 Courthouse Pkwy., Washington Court House, OH 43160 ~32.23 miles north of 45646
  • Mid-scale Rural property
  • 75 sleeping rooms in hotel
From$96
Very good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Washington Court House : 1810 Victoria St.
+1-888-675-2083
1810 Victoria St., Washington Court House, OH 43160 ~33.76 miles north of 45646
  • Two star hotel
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn : 8226 Ohio River Rd.
+1-800-716-8490
8226 Ohio River Rd., Wheelersburg, OH 45694 ~34.63 miles southeast of 45646
  • Low Cost hotel
  • Check in: 15:00
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Red Roof Inn Wheelersburg
+1-800-805-5223
8340 Ohio River Rd., Wheelersburg, OH 45694 ~34.79 miles southeast of 45646
  • Two-star Highway hotel
  • Hotel has 53 rooms
From$71
Very good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express Wilmington by IHG in Wilmington
+1-888-965-1860
155 Holiday Dr., Wilmington, OH 45177 ~36.32 miles northwest of 45646
  • Mid-scale Rural property
  • 74 rooms in hotel
From$99
Very good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn & Suites Wilmington
+1-888-788-5576
201 Holiday Dr., Wilmington, OH 45177 ~36.44 miles northwest of 45646
  • 3-star Rural hotel
  • Access to gym on-site
From$72
Very good 4.5 /5 Read Reviews Call BookMore Details
Wilmington Inn Wilmington
+1-888-897-9207
909 Fife Ave., Wilmington, OH 45177 ~36.56 miles northwest of 45646
  • Two star property
  • Check in time: 15:00
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Royalton Inn and Suites Wilmington - Wilmington
+1-888-311-4278
201 Carrie Dr., Wilmington, OH 45177 ~36.56 miles northwest of 45646
  • 2-star hotel
  • Hotel has 2 floors
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn in Jackson
+1-888-469-4795
605 East Main St., Jackson, OH 45640 ~37.70 miles east of 45646
  • Midscale property
  • Check in time: 15:00
From$90
Average 3.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Maysville Kentucky - Maysville
+1-888-734-9421
484 Moody Dr., Maysville, KY 41056 ~37.92 miles southwest of 45646
  • Economy hotel
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Jackson
+1-888-841-5292
972 East Main St., Jackson, OH 45640 ~37.94 miles east of 45646
  • Low Cost Rural hotel
  • 48 rooms in property
From$84
Average 3.0 /5 Recent Reviews Call BookMore Details
Deer Creek Lodge & Conference Center : 22300 State Park Rd. 20
+1-888-455-5160
22300 State Park Rd. 20, Mount Sterling, OH 43143 ~38.55 miles north of 45646
  • Midscale Resort property
  • Check-in time: 3pm
From$99
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Inn Maysville
+1-888-965-8297
1428a Us 68, Maysville, KY 41056 ~39.02 miles southwest of 45646
  • Cheap hotel
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Jackson, OH
+1-888-906-6358
1000 Acy Ave., Jackson, OH 45640 ~39.10 miles east of 45646
  • Economical Rural property
  • Fitness / Gym is on-site
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Maysville Ky
+1-888-749-6785
550 Tucker Dr., Maysville, KY 41056 ~39.46 miles southwest of 45646
  • Cheap Suburban property
From$60
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites : 24517 Us Highway 23s
+1-888-878-9982
24517 Us Highway 23s, Circleville, OH 43113 ~40.34 miles northeast of 45646
  • 2-star Rural hotel
  • Free complimentary breakfast
From$89
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn by Hilton Washington Court House
+1-888-389-4485
11484 Allen Rd., Jeffersonville, OH 43128 ~40.61 miles north of 45646
  • Three Star Highway property
  • Check in time: 3.00
From$75
Very good 4.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Washington Court House
+1-888-389-4121
11431 Allen Rd., Jeffersonville, OH 43128 ~40.63 miles north of 45646
  • 2 star Highway property
  • Hotel has a green policy Learn more
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites Jeffersonville I-71 - Jeffersonville
+1-888-675-2083
11349 Allen Rd. Nw, Jeffersonville, OH 43128 ~40.67 miles north of 45646
  • Three Star Highway property
  • Gym is available on property
From$90
Very good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Circleville An Ihg Hotel
+1-800-716-8490
23911 Us 23, Circleville, OH 43113 ~40.83 miles northeast of 45646
  • Affordable Rural property
  • Free breakfast
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Circleville
+1-800-805-5223
1520 South Court St., Circleville, OH 45113 ~40.84 miles northeast of 45646
  • Mid-scale hotel
  • 87 sleeping rooms in hotel
From$90
Very good 4.0 /5 Review Score Call BookMore Details
Rodeway Inn
+1-888-965-1860
23897 Us Route 23 South, Circleville, OH 43113 ~40.93 miles northeast of 45646
  • Low-priced hotel
  • 70 rooms in property
Rodeway Inn
+1-888-788-5576
9060 West Lancaster Rd., Jeffersonville, OH 43128 ~41.05 miles north of 45646
  • Low Cost property
  • 37 rooms in property
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Wilmington by IHG in Wilmington
+1-888-897-9207
123 Gano Rd., Wilmington, OH 45177 ~41.57 miles northwest of 45646
  • Affordable Convention Center hotel
  • Gym / Fitness Center Available
From$104
Very good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn Washington Court House - Jeffersonville
+1-888-311-4278
10160 Carr Rd., Jeffersonville, OH 43128 ~41.78 miles north of 45646
  • Low Cost Highway property
  • 5 suites in hotel
From$50
Average 3.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Batavia Ohio : 2188 Winemiller Ln
+1-888-469-4795
2188 Winemiller Ln, Batavia, OH 45103 ~44.04 miles west of 45646
  • Two-star Lake hotel
  • Fitness / Gym is on-site
From$94
Average 3.0 /5 Review Score Call BookMore Details

Next: Show All Available 45646 Hotels with Pricing

Graph: Upcoming 20 Days of Piketon Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Piketon, OH discounts available. The chart reflects the cheapest Piketon hotel for each day and each star rating category.

FAQs about hotels near 45646

What are the top reviewed hotels near 45646?

Christopher Inn and Suites, Hampton Inn & Suites Wilmington and Quality Inn Seaman are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels near 45646?

Comfort Inn, Shawnee Lodge & Conference Center and Hampton Inn & Suites Chillicothe are the top 3 luxury hotels near 45646.

What hotels are closest to the area of 45646?

Quality Inn Seaman, Greystone Motel, and Comfort Inn are the properties closest to 45646.

How much does a 3 star hotel near 45646 cost per night?

In the last year, the average 3 star hotel near 45646 has been $98.40 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 45646?

Christopher Inn and Suites, Greystone Motel and Countryside Inn & Suites are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 45646?

Fairfield Inn and Suites by Marriott Chillicothe and Fairfield Inn & Suites Jeffersonville I-71 are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 45646?

Quality Inn Seaman, Comfort Inn and Quality Inn & Suites are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 45646?

Holiday Inn Express Chillicothe East by IHG, Holiday Inn Portsmouth Downtown, an IHG Hotel and Holiday Inn Express Washington Court House by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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