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65280 Hotels & Accommodations

America's Value Inn Mexico : 4224 South Clark St. 4224 South Clark St., Mexico, MO 65265 ~11.57 miles west of 65280
  • Two star Airport property
  • Check in time: 2:00 pm
From$35
Very good 4.0 /5 Reviews Call BookMore Details
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Days Inn by Wyndham Mexico 2902 South Clark, Mexico, MO 65265 ~11.64 miles west of 65280
  • 2-star Suburban hotel
  • Gym / Fitness Center Available
From$60
Average 3.0 /5 Reviews Call BookMore Details
Best Western Teal Lake Inn 3602 South Clark St., Mexico, MO 65265 ~12.14 miles west of 65280
  • Midscale Suburban property
  • Fitness + Health Center
From$64
Very good 4.0 /5 Reviews Call BookMore Details
Country Hearth Inn & Suites Mexico 900 Vance Rd., Mexico, MO 65265 ~12.88 miles west of 65280
  • Affordable Highway property
  • Gym / Fitness Center Available
From$44
Average 3.5 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham 5750 Jade Rd., Kingdom City, MO 65262 ~22.04 miles southwest of 65280
  • Low-priced Highway hotel
  • 54 rooms in hotel
From$73
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Kingdom City in Kingdom City 3370 Gold Ave., Kingdom City, MO 65262 ~22.51 miles southwest of 65280
  • Economical Suburban property
  • Free breakfast
From$60
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn Kingdom City I-70 - Kingdom City 3207 County Rd. 211, Kingdom City, MO 65262 ~22.52 miles southwest of 65280
  • Three Star Highway property
  • 2 suites in property
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Kingdom City by IHG 3257 County Rd. 211, Kingdom City, MO 65262 ~22.59 miles southwest of 65280
  • Two-star property
  • Check-in time: 15:00
From$60
Very good 4.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Kingdom City 3391 County Rd. 211, Kingdom City, MO 65262 ~22.64 miles southwest of 65280
  • Economy Highway hotel
  • Check in: 15:00
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Americas Best Value Inn New Florence 202 Clark Dr., New Florence, MO 63363 ~23.00 miles southeast of 65280
  • Inexpensive property
  • Hotel has 47 rooms
From$46
Poor 2.0 /5 Reviews Call BookMore Details
Knights Inn New Florence : 403 Booneslick Rd. 403 Booneslick Rd., New Florence, MO 63363 ~23.07 miles southeast of 65280
  • Two star hotel
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
America's Best Inn New Florence 1 Proactive Dr., New Florence, MO 63363 ~23.32 miles southeast of 65280
  • Cheap hotel
From$60
Very good 4.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Fulton - Fulton 2205 Cardinal Dr., Fulton, MO 65251 ~26.72 miles southwest of 65280
  • Three Star Rural hotel
  • Check in: 3:00 PM
From$60
Very good 4.0 /5 Guest Reviews Call BookMore Details
Motel 70 930 Tree Farm Rd., High Hill, MO 65330 ~27.22 miles southeast of 65280
  • Inexpensive hotel
  • Check in time: 1:00 PM
From$30
Very good 4.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Bowling Green - Bowling Green 1216 East Champ Clark Dr., Bowling Green, MO 63334 ~28.24 miles east of 65280
  • Two star Rural property
  • Comp. Breakfast
From$56
Very good 4.0 /5 Review Score Call BookMore Details
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Capital O Amerihost Inn and Suites Fulton Hwy 54 MO 556 Amerihost Dr., Fulton, MO 65251 ~28.59 miles southwest of 65280
  • 2 star Highway property
  • Hotel has 62 rooms
From$60
Very good 4.0 /5 Reviews Call BookMore Details
FairBridge Inn Express, Monroe City in Monroe City 3 Gateway Sq. Dr., Monroe City, MO 63456 ~32.27 miles north of 65280
  • Two star Suburban hotel
  • Check-in time: 3:00 pm
From$60
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Columbia East 5700 Freedom Dr., Columbia, MO 65202 ~34.66 miles west of 65280
  • Low-priced Highway hotel
  • Check in: 2 P.M.
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Columbia East An Ihg Hotel in Columbia 915 Port Way, Columbia, MO 65201 ~34.83 miles west of 65280
  • Two-star Suburban hotel
  • Fitness + Health Center
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hilton Garden Inn Columbia 3300 Vandiver Dr., Columbia, MO 65202 ~36.10 miles west of 65280
  • Three Star Suburban property
  • Check-in time: 3:00PM
From$93
Very good 4.0 /5 Latest Reviews Call BookMore Details
Springhill Suites by Marriott Columbia - Columbia 3415 Clark Lane, Columbia, MO 65202 ~36.19 miles west of 65280
  • Three Star Highway property
  • Hotel has 82 rooms
From$129
Average 3.0 /5 Read Reviews Call BookMore Details
Residence Inn by Marriott Columbia 1100 Woodland Springs Court, Columbia, MO 65202 ~36.20 miles west of 65280
  • Three Star Suburban property
  • 4 floors in hotel
From$80
Very good 4.0 /5 Latest Reviews Call BookMore Details
Candlewood Suites Columbia East by IHG 1400 Creekwood Pkwy., Columbia, MO 65202 ~36.27 miles west of 65280
  • Low Cost Suburban hotel
  • Check-in: 3:00pm
From$55
Very good 4.0 /5 Review Score Call BookMore Details
Fairfield Inn & Suites by Marriott Columbia 1115 Woodland Springs Court, Columbia, MO 65202 ~36.27 miles west of 65280
  • Affordable Highway property
  • Access to gym on-site
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Columbia : 3410 Clark Lane 3410 Clark Lane, Columbia, MO 65202 ~36.34 miles west of 65280
  • Midscale Highway hotel
  • 120 rooms in property
From$99
Very good 4.5 /5 Recent Reviews Call BookMore Details
Motel 6 Columbia East Mo 3402 Interstate 70 Dr. Southeast, Columbia, MO 65201 ~36.34 miles west of 65280
  • Two star hotel
  • 3 floors in property
From$60
Very good 4.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Columbia Clark Lane in Columbia 3216 Clark Lane, Columbia, MO 65202 ~36.43 miles west of 65280
  • Cheap Highway hotel
  • Check-in: 11:00 AM
Quality Inn & Suites Columbia I-70 801 Keene St., Columbia, MO 65201 ~36.49 miles west of 65280
  • Economy Downtown property
  • 60 sleeping rooms in hotel
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Staybridge Suites Columbia by IHG - Columbia 805 Keene St., Columbia, MO 65201 ~36.49 miles west of 65280
  • Midscale Suburban property
  • 4 floors in hotel
From$66
Very good 4.5 /5 Latest Reviews Call BookMore Details
Howard Johnson Inn Columbia 3100 I 70 Dr. Southeast, Columbia, MO 65201 ~36.52 miles west of 65280
  • 2 star Highway hotel
  • Check-in time: 11:00 AM
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Drury Plaza Hotel Columbia East : 3100 Interstate 70 Dr. Se 3100 Interstate 70 Dr. Se, Columbia, MO 65201 ~36.53 miles west of 65280
  • Midscale Suburban hotel
  • Gym is available on property
From$136
Average 3.0 /5 Review Score Call BookMore Details
Country Inn & Suites by Radisson, Columbia, MO 817 North Keene St., Columbia, MO 65201 ~36.57 miles west of 65280
  • Midscale Highway hotel
  • Check in time: 03:00 PM
From$80
Very good 4.5 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites Columbia I 70 in Columbia 801 North Keene St., Columbia, MO 65201 ~36.60 miles west of 65280
  • Midscale Downtown hotel
  • Fitness + Health Center
From$52
Average 3.5 /5 Guest Reviews Call BookMore Details
Best Western Plus Columbia Inn 2904 Clark Ln, Columbia, MO 65202 ~36.64 miles west of 65280
  • Economical Suburban hotel
  • Free breakfast available
From$80
Very good 4.0 /5 Review Score Call BookMore Details
Wingate by Wyndham - Columbia - Columbia 3101 Wingate Court, Columbia, MO 65201 ~36.67 miles west of 65280
  • Midscale Highway hotel
  • 3 floors in hotel
From$89
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Ramada by Wyndham Columbia 901 Conley Rd., Columbia, MO 65201 ~36.72 miles west of 65280
  • 2 star Highway property
  • Fitness + Health Center
From$54
Average 3.5 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Hannibal - Hannibal 4141 Market St., Hannibal, MO 63401 ~36.99 miles northeast of 65280
  • Two star Convention Center hotel
  • 5 meeting rooms in property
From$35
Average 3.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Hannibal 4070 Market St., Hannibal, MO 63401 ~37.03 miles northeast of 65280
  • Economy hotel
  • 2 floors in property
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn & Suites - Hannibal 4000 Market St., Hannibal, MO 63401 ~37.07 miles northeast of 65280
  • Two-star Highway hotel
  • Check-in: 3:00 PM
From$75
Very good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by I - Columbia 1402 Cinnamon Hill Lane, Columbia, MO 65201 ~37.49 miles west of 65280
  • 3 star Highway hotel
  • 121 rooms in property
From$80
Very good 4.0 /5 Guest Reviews Call BookMore Details
Budget Host Inn 900 Vandiver Dr., Columbia, MO 65202 ~38.03 miles west of 65280
  • Low Cost Highway property
  • 156 sleeping rooms in hotel
From$40
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 Hannibal, MO - Hannibal 123 Huckleberry Heights Dr., Hannibal, MO 63401 ~38.13 miles northeast of 65280
  • Two-star hotel
  • 2 floors in hotel
From$60
Average 3.5 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Columbia Missouri : 3301 Lemone Industrial Blvd. 3301 Lemone Industrial Blvd., Columbia, MO 65201 ~38.17 miles southwest of 65280
  • Affordable Highway hotel
  • Hotel has 4 floors
From$99
Very good 4.5 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Hannibal - Hannibal 120 Huckleberry Heights Dr., Hannibal, MO 63401 ~38.18 miles northeast of 65280
  • Low priced Highway hotel
  • 2 floors in hotel
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Sleep Inn & Suites Hannibal West 105 Lakeside Dr., Hannibal, MO 63401 ~38.19 miles north of 65280
  • Inexpensive hotel
  • 10 suites in property
From$109
Very good 4.0 /5 Read Reviews Call BookMore Details
Towneplace Suites by Marriott Columbia : 4400 Nocona Pkwy. 4400 Nocona Pkwy., Columbia, MO 65201 ~38.43 miles southwest of 65280
  • Affordable hotel
  • Hotel has 99 rooms
From$85
Average 3.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Warrenton 425 East Veterans Memorial Pkwy., Warrenton, MO 63383 ~38.43 miles southeast of 65280
  • Cheap Rural hotel
  • Complimentary breakfast is offered
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn Columbia, MO in Columbia 201 East Texas Ave., Columbia, MO 65202 ~38.46 miles west of 65280
  • Midscale Suburban property
  • Check in time: 1:00 PM
From$44
Average 3.0 /5 Latest Reviews Call BookMore Details
The Broadway Columbia a Doubletree by Hilton in Columbia 1111 East Broadway, Columbia, MO 65201 ~38.48 miles west of 65280
  • High-end Downtown property
  • Gym is available on property
From$143
Very good 4.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Hannibal West 120 Lindsey Dr., Hannibal, MO 63401 ~38.51 miles north of 65280
  • 3 star hotel
  • Hotel has 17 suites
From$67
Very good 4.0 /5 Latest Reviews Call BookMore Details

Next: Show All Available 65280 Hotels with Pricing

Graph: Upcoming 20 Days of 65280 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Mexico, MO discounts available. The chart reflects the cheapest Mexico hotel for each day and each star rating category.

FAQs about hotels near 65280

What are the top rated hotels near 65280?

Hampton Inn Columbia, Staybridge Suites Columbia by IHG and Country Inn & Suites by Radisson, Columbia, MO are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 65280?

The Broadway Columbia a Doubletree by Hilton, Best Western Teal Lake Inn and Country Hearth Inn & Suites Mexico are the top 3 luxury hotels near 65280.

What hotels are closest to the area of 65280?

America's Value Inn Mexico, Days Inn by Wyndham Mexico, and Best Western Teal Lake Inn are the properties closest to 65280.

How much does a cheap hotel near 65280 cost per night?

In the last year, a 2 star hotel near 65280 can be as cheap as $63.47 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 65280 cost per night?

In the last year, the average 3 star hotel near 65280 has been $98.83 per night. (based on HotelPlanner prices)

How much does a higher-end hotel near 65280 cost?

In the last year, the average 4 star hotel near 65280 has been $160.00 per night. (based on HotelPlanner prices)

What are the best independent hotels near 65280?

America's Value Inn Mexico, America's Best Inn New Florence and Motel 70 are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 65280?

Courtyard by Marriott Columbia Missouri, Residence Inn by Marriott Columbia and Springhill Suites by Marriott Columbia are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 65280?

Comfort Inn & Suites - Hannibal, Sleep Inn & Suites Hannibal West and Quality Inn & Suites Hannibal West are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best Best Western hotels near 65280?

Best Western Teal Lake Inn and Best Western Plus Columbia Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the most popular IHG hotels near 65280?

Staybridge Suites Columbia by IHG, Holiday Inn Express & Suites Kingdom City by IHG and Candlewood Suites Columbia East by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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