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65280 Hotels/Motels & Accommodations

America's Value Inn Mexico 4224 South Clark St., Mexico, MO 65265 ~11.57 miles west of 65280
  • Low Cost Airport property
  • Complimentary breakfast is offered
From$35
Very Good 4.0 /5 Latest Reviews Call BookMore Details
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Days Inn by Wyndham Mexico 2902 South Clark, Mexico, MO 65265 ~11.64 miles west of 65280
  • Low priced Suburban property
  • Check-in: 11:00 AM
From$60
Average 3.0 /5 Reviews Call BookMore Details
Best Western Teal Lake Inn in Mexico 3602 South Clark St., Mexico, MO 65265 ~12.14 miles west of 65280
  • Three Star Suburban property
  • 48 rooms in hotel
From$63
Very Good 4.0 /5 Reviews Call BookMore Details
Country Hearth Inn & Suites Mexico 900 Vance Rd., Mexico, MO 65265 ~12.88 miles west of 65280
  • 3-star Highway property
  • Hotel has 61 rooms
From$44
Average 3.5 /5 Review Score Call BookMore Details
Baymont by Wyndham - Kingdom City 5750 Jade Rd., Kingdom City, MO 65262 ~22.04 miles southwest of 65280
  • 2 star Highway hotel
  • Gym / Fitness Center Available
From$73
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Kingdom City : 3370 Gold Ave. 3370 Gold Ave., Kingdom City, MO 65262 ~22.51 miles southwest of 65280
  • Low Cost Suburban property
  • Check in time: 2:00pm
From$60
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn Kingdom City I-70 in Kingdom City 3207 County Rd. 211, Kingdom City, MO 65262 ~22.52 miles southwest of 65280
  • 3-star Highway hotel
  • Fitness / Gym is on-site
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Kingdom City by IHG 3257 County Rd. 211, Kingdom City, MO 65262 ~22.59 miles southwest of 65280
  • Low-priced hotel
  • Fitness / Gym is on-site
From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Kingdom City : 3391 County Rd. 211 3391 County Rd. 211, Kingdom City, MO 65262 ~22.64 miles southwest of 65280
  • Cheap Highway property
  • Check-in time: 15:00
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Americas Best Value Inn New Florence - New Florence 202 Clark Dr., New Florence, MO 63363 ~23.00 miles southeast of 65280
  • Cheap property
  • Free complimentary breakfast
Knights Inn New Florence - New Florence 403 Booneslick Rd., New Florence, MO 63363 ~23.07 miles southeast of 65280
  • Cheap property
From$60
Average 3.0 /5 Reviews Call BookMore Details
America's Best Inn New Florence 1 Proactive Dr., New Florence, MO 63363 ~23.32 miles southeast of 65280
  • Low-priced property
From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Fulton : 2205 Cardinal Dr. 2205 Cardinal Dr., Fulton, MO 65251 ~26.72 miles southwest of 65280
  • 3-star Rural property
  • Free breakfast available
From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Motel 70 in High Hill 930 Tree Farm Rd., High Hill, MO 65330 ~27.22 miles southeast of 65280
  • Low priced property
  • Check-in time: 1:00 PM
From$30
Very Good 4.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Bowling Green : 1216 East Champ Clark Dr. 1216 East Champ Clark Dr., Bowling Green, MO 63334 ~28.24 miles east of 65280
  • Cheap Rural hotel
  • 5 suites in hotel
From$56
Very Good 4.0 /5 Guest Reviews Call BookMore Details
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Capital O Amerihost Inn and Suites Fulton Hwy 54 MO in Fulton 556 Amerihost Dr., Fulton, MO 65251 ~28.59 miles southwest of 65280
  • Economical Highway property
  • 2 floors in hotel
From$60
Very Good 4.0 /5 Recent Reviews Call BookMore Details
FairBridge Inn Express, Monroe City - Monroe City 3 Gateway Sq. Dr., Monroe City, MO 63456 ~32.27 miles north of 65280
  • Cheap Suburban hotel
  • 47 rooms in property
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Columbia East in Columbia 5700 Freedom Dr., Columbia, MO 65202 ~34.66 miles west of 65280
  • Two star Highway property
  • Free complimentary breakfast
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Columbia East An Ihg Hotel 915 Port Way, Columbia, MO 65201 ~34.83 miles west of 65280
  • Two-star Suburban property
  • Hotel has 25 suites
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hilton Garden Inn Columbia in Columbia 3300 Vandiver Dr., Columbia, MO 65202 ~36.10 miles west of 65280
  • Three Star Suburban property
  • Hotel has an eco-friendly policy See policy
From$93
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Springhill Suites by Marriott Columbia 3415 Clark Lane, Columbia, MO 65202 ~36.19 miles west of 65280
  • Midscale Highway hotel
  • Fitness center on property
From$129
Average 3.0 /5 Latest Reviews Call BookMore Details
Residence Inn by Marriott Columbia - Columbia 1100 Woodland Springs Court, Columbia, MO 65202 ~36.20 miles west of 65280
  • Midscale Suburban property
  • Hotel has 80 rooms
From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Candlewood Suites Columbia East by IHG 1400 Creekwood Pkwy., Columbia, MO 65202 ~36.27 miles west of 65280
  • 2-star Suburban property
  • Fitness center on property
From$55
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Columbia - Columbia 1115 Woodland Springs Court, Columbia, MO 65202 ~36.27 miles west of 65280
  • Three Star Highway hotel
  • Free comp. breakfast
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Columbia : 3410 Clark Lane 3410 Clark Lane, Columbia, MO 65202 ~36.34 miles west of 65280
  • 3-star Highway property
  • Free breakfast
From$99
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Motel 6 Columbia East Mo : 3402 Interstate 70 Dr. Southeast 3402 Interstate 70 Dr. Southeast, Columbia, MO 65201 ~36.34 miles west of 65280
  • Low Cost property
  • 61 rooms in property
From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Columbia Clark Lane in Columbia 3216 Clark Lane, Columbia, MO 65202 ~36.43 miles west of 65280
  • Low priced Highway property
  • Hotel has 73 rooms
Quality Inn & Suites Columbia I-70 - Columbia 801 Keene St., Columbia, MO 65201 ~36.49 miles west of 65280
  • Economy Downtown hotel
  • Has environment-friendly policy Read more
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Staybridge Suites Columbia by IHG : 805 Keene St. 805 Keene St., Columbia, MO 65201 ~36.49 miles west of 65280
  • Affordable Suburban hotel
  • Free complimentary breakfast
From$66
Very Good 4.5 /5 Review Score Call BookMore Details
Howard Johnson Inn Columbia 3100 I 70 Dr. Southeast, Columbia, MO 65201 ~36.52 miles west of 65280
  • Low Cost Highway property
  • Check-in time: 11:00 AM
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Country Inn & Suites by Radisson, Columbia, MO 817 North Keene St., Columbia, MO 65201 ~36.57 miles west of 65280
  • Affordable Highway hotel
  • 85 rooms in property
From$80
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Columbia I 70 - Columbia 801 North Keene St., Columbia, MO 65201 ~36.60 miles west of 65280
  • Mid-scale Downtown property
  • Hotel has a green policy See policy
From$52
Average 3.5 /5 Recent Reviews Call BookMore Details
Best Western Plus Columbia Inn in Columbia 2904 Clark Ln, Columbia, MO 65202 ~36.64 miles west of 65280
  • Cheap Suburban property
  • Hotel has an eco-friendly policy Learn more
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Wingate by Wyndham - Columbia 3101 Wingate Court, Columbia, MO 65201 ~36.67 miles west of 65280
  • Affordable Highway hotel
  • 81 rooms in property
From$89
Very Good 4.0 /5 Reviews Call BookMore Details
Ramada by Wyndham Columbia : 901 Conley Rd. 901 Conley Rd., Columbia, MO 65201 ~36.72 miles west of 65280
  • Two star Highway hotel
  • Access to gym on-site
From$54
Average 3.5 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Hannibal 4141 Market St., Hannibal, MO 63401 ~36.99 miles northeast of 65280
  • Low-priced Convention Center hotel
  • 4 suites in property
From$35
Average 3.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Hannibal : 4070 Market St. 4070 Market St., Hannibal, MO 63401 ~37.03 miles northeast of 65280
  • Economical property
  • 63 sleeping rooms in hotel
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites - Hannibal in Hannibal 4000 Market St., Hannibal, MO 63401 ~37.07 miles northeast of 65280
  • Two-star Highway hotel
  • Hotel has a green policy Read more
From$75
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by I 1402 Cinnamon Hill Lane, Columbia, MO 65201 ~37.49 miles west of 65280
  • Three Star Highway property
  • 69 suites in hotel
From$80
Very Good 4.0 /5 Reviews Call BookMore Details
Budget Host Inn in Columbia 900 Vandiver Dr., Columbia, MO 65202 ~38.03 miles west of 65280
  • Economical Highway property
  • Hotel has a green policy Learn more
From$40
Average 3.0 /5 Latest Reviews Call BookMore Details
Motel 6 Hannibal, MO 123 Huckleberry Heights Dr., Hannibal, MO 63401 ~38.13 miles northeast of 65280
  • Economical hotel
  • Hotel has 2 floors
From$60
Average 3.5 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Columbia Missouri in Columbia 3301 Lemone Industrial Blvd., Columbia, MO 65201 ~38.17 miles southwest of 65280
  • Midscale Highway property
  • Hotel has 4 floors
From$99
Very Good 4.5 /5 Reviews Call BookMore Details
Super 8 by Wyndham Hannibal : 120 Huckleberry Heights Dr. 120 Huckleberry Heights Dr., Hannibal, MO 63401 ~38.18 miles northeast of 65280
  • Low priced Highway property
  • Check-in time: 11:00 AM
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Sleep Inn & Suites Hannibal West : 105 Lakeside Dr. 105 Lakeside Dr., Hannibal, MO 63401 ~38.19 miles north of 65280
  • Low-priced property
  • Free breakfast
From$109
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Towneplace Suites by Marriott Columbia in Columbia 4400 Nocona Pkwy., Columbia, MO 65201 ~38.43 miles southwest of 65280
  • Mid-scale hotel
  • 99 suites in hotel
From$85
Average 3.0 /5 Recent Reviews Call BookMore Details
Baymont by Wyndham Warrenton in Warrenton 425 East Veterans Memorial Pkwy., Warrenton, MO 63383 ~38.43 miles southeast of 65280
  • Economy Rural property
  • Free comp. breakfast
From$60
Average 3.0 /5 Review Score Call BookMore Details
Red Roof Inn Columbia, MO 201 East Texas Ave., Columbia, MO 65202 ~38.46 miles west of 65280
  • 3-star Suburban property
  • Check-in time: 1:00 PM
From$44
Average 3.0 /5 Review Score Call BookMore Details
The Broadway Columbia a Doubletree by Hilton 1111 East Broadway, Columbia, MO 65201 ~38.48 miles west of 65280
  • High end Downtown hotel
  • 6 suites in hotel
From$143
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites Hannibal West 120 Lindsey Dr., Hannibal, MO 63401 ~38.51 miles north of 65280
  • 3 star hotel
  • 17 suites in property
From$67
Very Good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express Warrenton by IHG in Warrenton 1008 North Highway 47, Warrenton, MO 63383 ~38.54 miles southeast of 65280
  • Two star Suburban property
  • Fitness / Gym is on-site
From$105
Very Good 4.0 /5 Hotel Reviews Call BookMore Details

Next: Show All Available 65280 Hotels with Pricing

Graph: Upcoming 20 Days of 65280 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Mexico, MO discounts available. The chart reflects the cheapest Mexico hotel for each day and each star rating category.

FAQs about hotels near 65280

What are the top rated hotels near 65280?

Hampton Inn Columbia, Staybridge Suites Columbia by IHG and Country Inn & Suites by Radisson, Columbia, MO are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 65280?

The Broadway Columbia a Doubletree by Hilton, Best Western Teal Lake Inn and Country Hearth Inn & Suites Mexico are the top 3 luxury hotels near 65280.

What hotels are closest to the area of 65280?

America's Value Inn Mexico, Days Inn by Wyndham Mexico, and Best Western Teal Lake Inn are the properties closest to 65280.

How much does a cheap hotel near 65280 cost per night?

In the last year, a 2 star hotel near 65280 can be as cheap as $63.47 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 65280 cost per night?

In the last year, the average 3 star hotel near 65280 has been $98.83 per night. (based on HotelPlanner prices)

How much does a higher-end hotel near 65280 cost?

In the last year, the average 4 star hotel near 65280 has been $160.00 per night. (based on HotelPlanner prices)

What are the best independent hotels near 65280?

America's Value Inn Mexico, America's Best Inn New Florence and Motel 70 are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 65280?

Courtyard by Marriott Columbia Missouri, Residence Inn by Marriott Columbia and Springhill Suites by Marriott Columbia are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 65280?

Comfort Inn & Suites - Hannibal, Sleep Inn & Suites Hannibal West and Quality Inn & Suites Hannibal West are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best Best Western hotels near 65280?

Best Western Teal Lake Inn and Best Western Plus Columbia Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the most popular IHG hotels near 65280?

Staybridge Suites Columbia by IHG, Holiday Inn Express & Suites Kingdom City by IHG and Candlewood Suites Columbia East by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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