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65280 Hotels, Motels & Accommodations

America's Value Inn Mexico - Mexico 4224 South Clark St., Mexico, MO 65265 ~11.57 miles west of 65280
  • Cheap Airport property
  • Free comp. breakfast
From$35
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
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Days Inn by Wyndham Mexico : 2902 South Clark 2902 South Clark, Mexico, MO 65265 ~11.64 miles west of 65280
  • Economical Suburban hotel
  • Free complimentary breakfast
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Best Western Teal Lake Inn 3602 South Clark St., Mexico, MO 65265 ~12.14 miles west of 65280
  • Affordable Suburban hotel
  • Fitness center on property
From$64
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Country Hearth Inn & Suites Mexico - Mexico 900 Vance Rd., Mexico, MO 65265 ~12.88 miles west of 65280
  • 3-star Highway property
  • Check in time: 3:00 PM
From$44
Average 3.5 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham - Kingdom City 5750 Jade Rd., Kingdom City, MO 65262 ~22.04 miles southwest of 65280
  • Low-priced Highway hotel
  • Has environment-friendly policy Read more
From$73
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Kingdom City in Kingdom City 3370 Gold Ave., Kingdom City, MO 65262 ~22.51 miles southwest of 65280
  • Two-star Suburban property
  • Check-in: 2:00pm
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn Kingdom City I-70 3207 County Rd. 211, Kingdom City, MO 65262 ~22.52 miles southwest of 65280
  • Affordable Highway property
  • Check-in: 3:00 PM
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Kingdom City by IHG - Kingdom City 3257 County Rd. 211, Kingdom City, MO 65262 ~22.59 miles southwest of 65280
  • Two star property
  • Gym / Fitness Center Available
From$60
Very Good 4.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Kingdom City : 3391 County Rd. 211 3391 County Rd. 211, Kingdom City, MO 65262 ~22.64 miles southwest of 65280
  • Low Cost Highway hotel
  • Check in time: 15:00
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Americas Best Value Inn New Florence 202 Clark Dr., New Florence, MO 63363 ~23.00 miles southeast of 65280
  • Cheap hotel
  • 47 sleeping rooms in hotel
Knights Inn New Florence : 403 Booneslick Rd. 403 Booneslick Rd., New Florence, MO 63363 ~23.07 miles southeast of 65280
  • Two-star hotel
From$60
Average 3.0 /5 Reviews Call BookMore Details
America's Best Inn New Florence : 1 Proactive Dr. 1 Proactive Dr., New Florence, MO 63363 ~23.32 miles southeast of 65280
  • Two star property
From$60
Very Good 4.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Fulton 2205 Cardinal Dr., Fulton, MO 65251 ~26.72 miles southwest of 65280
  • 3 star Rural property
  • Hotel has 63 rooms
From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Motel 70 930 Tree Farm Rd., High Hill, MO 65330 ~27.22 miles southeast of 65280
  • Economical hotel
  • 13 rooms in hotel
From$30
Very Good 4.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Bowling Green 1216 East Champ Clark Dr., Bowling Green, MO 63334 ~28.24 miles east of 65280
  • Two star Rural property
  • Comp. Breakfast
From$56
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
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Capital O Amerihost Inn and Suites Fulton Hwy 54 MO in Fulton 556 Amerihost Dr., Fulton, MO 65251 ~28.59 miles southwest of 65280
  • Cheap Highway property
  • Fitness center on property
From$60
Very Good 4.0 /5 Recent Reviews Call BookMore Details
FairBridge Inn Express, Monroe City - Monroe City 3 Gateway Sq. Dr., Monroe City, MO 63456 ~32.27 miles north of 65280
  • Low priced Suburban hotel
  • Hotel has 2 floors
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Columbia East 5700 Freedom Dr., Columbia, MO 65202 ~34.66 miles west of 65280
  • Two-star Highway property
  • Check-in: 2 P.M.
From$60
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Columbia East An Ihg Hotel 915 Port Way, Columbia, MO 65201 ~34.83 miles west of 65280
  • Inexpensive Suburban hotel
  • Airport shuttle provided
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Hilton Garden Inn Columbia in Columbia 3300 Vandiver Dr., Columbia, MO 65202 ~36.10 miles west of 65280
  • Midscale Suburban hotel
  • 12 conference rooms in property
From$93
Very Good 4.0 /5 Read Reviews Call BookMore Details
Springhill Suites by Marriott Columbia : 3415 Clark Lane 3415 Clark Lane, Columbia, MO 65202 ~36.19 miles west of 65280
  • 3 star Highway property
  • Comp. Breakfast
From$129
Average 3.0 /5 Latest Reviews Call BookMore Details
Residence Inn by Marriott Columbia in Columbia 1100 Woodland Springs Court, Columbia, MO 65202 ~36.20 miles west of 65280
  • 3-star Suburban hotel
  • Complimentary breakfast is offered
From$80
Very Good 4.0 /5 Reviews Call BookMore Details
Candlewood Suites Columbia East by IHG : 1400 Creekwood Pkwy. 1400 Creekwood Pkwy., Columbia, MO 65202 ~36.27 miles west of 65280
  • Low priced Suburban property
  • Fitness / Gym is on-site
From$55
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Columbia in Columbia 1115 Woodland Springs Court, Columbia, MO 65202 ~36.27 miles west of 65280
  • Midscale Highway hotel
  • 3 floors in hotel
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Columbia 3410 Clark Lane, Columbia, MO 65202 ~36.34 miles west of 65280
  • Affordable Highway hotel
  • 120 rooms in property
From$99
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Motel 6 Columbia East Mo 3402 Interstate 70 Dr. Southeast, Columbia, MO 65201 ~36.34 miles west of 65280
  • 2 star hotel
  • Check in: 15:00
From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Columbia Clark Lane 3216 Clark Lane, Columbia, MO 65202 ~36.43 miles west of 65280
  • Two-star Highway hotel
  • Hotel has 73 rooms
Quality Inn & Suites Columbia I-70 801 Keene St., Columbia, MO 65201 ~36.49 miles west of 65280
  • Low Cost Downtown hotel
  • Check in time: 3:00 pm
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Staybridge Suites Columbia by IHG 805 Keene St., Columbia, MO 65201 ~36.49 miles west of 65280
  • Three Star Suburban hotel
  • 81 suites in hotel
From$66
Very Good 4.5 /5 Reviews Call BookMore Details
Howard Johnson Inn Columbia - Columbia 3100 I 70 Dr. Southeast, Columbia, MO 65201 ~36.52 miles west of 65280
  • Cheap Highway hotel
  • Check-in time: 11:00 AM
From$60
Average 3.0 /5 Review Score Call BookMore Details
Drury Plaza Hotel Columbia East in Columbia 3100 Interstate 70 Dr. Se, Columbia, MO 65201 ~36.53 miles west of 65280
  • Affordable Suburban property
  • Fitness center on property
From$136
Average 3.0 /5 Recent Reviews Call BookMore Details
Country Inn & Suites by Radisson Columbia Mo : 817 North Keene St. 817 North Keene St., Columbia, MO 65201 ~36.57 miles west of 65280
  • Three Star Highway hotel
  • 85 rooms in hotel
From$80
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites Columbia I 70 in Columbia 801 North Keene St., Columbia, MO 65201 ~36.60 miles west of 65280
  • Affordable Downtown hotel
  • Hotel has an eco-friendly policy Read more
From$52
Average 3.5 /5 Latest Reviews Call BookMore Details
Best Western Plus Columbia Inn 2904 Clark Ln, Columbia, MO 65202 ~36.64 miles west of 65280
  • Low-priced Suburban hotel
  • Gym is available on property
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Wingate by Wyndham - Columbia in Columbia 3101 Wingate Court, Columbia, MO 65201 ~36.67 miles west of 65280
  • Midscale Highway hotel
  • 4 suites in hotel
From$89
Very Good 4.0 /5 Review Score Call BookMore Details
Ramada by Wyndham Columbia - Columbia 901 Conley Rd., Columbia, MO 65201 ~36.72 miles west of 65280
  • Low Cost Highway hotel
  • Free breakfast
From$54
Average 3.5 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Hannibal : 4141 Market St. 4141 Market St., Hannibal, MO 63401 ~36.99 miles northeast of 65280
  • Cheap Convention Center hotel
  • 4 suites in property
From$35
Average 3.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Hannibal in Hannibal 4070 Market St., Hannibal, MO 63401 ~37.03 miles northeast of 65280
  • Low Cost hotel
  • Hotel has 2 floors
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites - Hannibal : 4000 Market St. 4000 Market St., Hannibal, MO 63401 ~37.07 miles northeast of 65280
  • Economical Highway hotel
  • 16 suites in hotel
From$75
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by I in Columbia 1402 Cinnamon Hill Lane, Columbia, MO 65201 ~37.49 miles west of 65280
  • 3-star Highway property
  • 121 rooms in property
From$80
Very Good 4.0 /5 Reviews Call BookMore Details
Budget Host Inn 900 Vandiver Dr., Columbia, MO 65202 ~38.03 miles west of 65280
  • Inexpensive Highway property
  • 2 floors in property
From$40
Average 3.0 /5 Reviews Call BookMore Details
Motel 6 Hannibal, MO : 123 Huckleberry Heights Dr. 123 Huckleberry Heights Dr., Hannibal, MO 63401 ~38.13 miles northeast of 65280
  • Two-star hotel
  • Check in: 14:00
From$60
Average 3.5 /5 Recent Reviews Call BookMore Details
Courtyard by Marriott Columbia Missouri 3301 Lemone Industrial Blvd., Columbia, MO 65201 ~38.17 miles southwest of 65280
  • 3 star Highway hotel
  • 133 rooms in hotel
From$99
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Hannibal : 120 Huckleberry Heights Dr. 120 Huckleberry Heights Dr., Hannibal, MO 63401 ~38.18 miles northeast of 65280
  • Inexpensive Highway property
  • Check-in time: 11:00 AM
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Sleep Inn & Suites Hannibal West in Hannibal 105 Lakeside Dr., Hannibal, MO 63401 ~38.19 miles north of 65280
  • Low-priced hotel
  • 3 floors in hotel
From$109
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Towneplace Suites by Marriott Columbia in Columbia 4400 Nocona Pkwy., Columbia, MO 65201 ~38.43 miles southwest of 65280
  • 3-star property
  • 99 rooms in hotel
From$85
Average 3.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Warrenton 425 East Veterans Memorial Pkwy., Warrenton, MO 63383 ~38.43 miles southeast of 65280
  • Two-star Rural hotel
  • 62 rooms in property
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Red Roof Inn Columbia, MO - Columbia 201 East Texas Ave., Columbia, MO 65202 ~38.46 miles west of 65280
  • 3 star Suburban hotel
  • Check in time: 1:00 PM
From$44
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The Broadway Columbia a Doubletree by Hilton 1111 East Broadway, Columbia, MO 65201 ~38.48 miles west of 65280
  • High-end Downtown property
  • Hotel has 6 floors
From$143
Very Good 4.0 /5 Review Score Call BookMore Details
Quality Inn & Suites Hannibal West : 120 Lindsey Dr. 120 Lindsey Dr., Hannibal, MO 63401 ~38.51 miles north of 65280
  • Three Star property
  • Hotel has 6 meeting rooms
From$67
Very Good 4.0 /5 Read Reviews Call BookMore Details

Next: Show All Available 65280 Hotels with Pricing

Graph: Upcoming 20 Days of 65280 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Mexico, MO discounts available. The chart reflects the cheapest Mexico hotel for each day and each star rating category.

FAQs about hotels near 65280

What are the top rated hotels near 65280?

Hampton Inn Columbia, Staybridge Suites Columbia by IHG and Country Inn & Suites by Radisson Columbia Mo are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 65280?

The Broadway Columbia a Doubletree by Hilton, Best Western Teal Lake Inn and Country Hearth Inn & Suites Mexico are the top 3 luxury hotels near 65280.

What hotels are closest to the area of 65280?

America's Value Inn Mexico, Days Inn by Wyndham Mexico, and Best Western Teal Lake Inn are the properties closest to 65280.

How much does a cheap hotel near 65280 cost per night?

In the last year, a 2 star hotel near 65280 can be as cheap as $63.47 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 65280 cost per night?

In the last year, the average 3 star hotel near 65280 has been $98.83 per night. (based on HotelPlanner prices)

How much does a higher-end hotel near 65280 cost?

In the last year, the average 4 star hotel near 65280 has been $160.00 per night. (based on HotelPlanner prices)

What are the best independent hotels near 65280?

America's Value Inn Mexico, America's Best Inn New Florence and Motel 70 are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 65280?

Courtyard by Marriott Columbia Missouri, Residence Inn by Marriott Columbia and Springhill Suites by Marriott Columbia are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 65280?

Comfort Inn & Suites - Hannibal, Sleep Inn & Suites Hannibal West and Quality Inn & Suites Hannibal West are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best Best Western hotels near 65280?

Best Western Teal Lake Inn and Best Western Plus Columbia Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the most popular IHG hotels near 65280?

Staybridge Suites Columbia by IHG, Holiday Inn Express & Suites Kingdom City by IHG and Candlewood Suites Columbia East by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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