Hotels in 78221 - San Antonio TX

Only hotels in 78221 zip code are listed below. Search for cheap and discount hotel rates in San Antonio, TX for your upcoming leisure or conference / group travel. We list the best 78221 hotels and motels so you can review the San Antonio hotel list below to find the perfect lodging. Hotels in Bexar county and area code 210 are also listed.

78221 Hotels & Accommodations

Holiday Inn Express & Suites San Antonio South : 11400 SE Loop 410 Acc Rd.
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
11400 SE Loop 410 Acc Rd., San Antonio, TX 78221 +1-888-389-4121
  • Three Star Suburban hotel
  • Fitness / Gym is on-site
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From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Best Western Plus Palo Alto Inn & Suites - San Antonio
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
12507 SW Loop 410, San Antonio, TX 78224 +1-888-675-2083 ~4.15 miles northwest of 78221
  • Affordable hotel
  • Hotel has 4 floors
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From$59
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham San Antonio at Palo Alto - San Antonio
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
9403 Poteet Jourdanton Freeway, San Antonio, TX 78224 +1-800-716-8490 ~4.59 miles northwest of 78221
  • Cheap Downtown property
  • Free comp. breakfast
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From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Woodspring Suites San Antonio South : 7958 Interstate 35 Access Rd.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
7958 Interstate 35 Access Rd., San Antonio, TX 78224 +1-800-805-5223 ~5.59 miles north of 78221
  • Low-priced Highway property
  • Hotel has 4 floors
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From$43
Average 3.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham San Antonio South Park
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
7202 South Pan Am Expressway, San Antonio, TX 78224 +1-888-965-1860 ~5.96 miles north of 78221
  • Affordable Highway property
  • Hotel has 2 floors
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From$80
Poor 2.0 /5 Read Reviews Call BookMore Details
Motel 6 San Antonio, TX - South
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
7950 South Panam Expy, San Antonio, TX 78224 +1-888-788-5576 ~6.31 miles north of 78221
  • Cheap property
  • 75 sleeping rooms in hotel
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From$60
Poor 2.5 /5 Review Score Call BookMore Details
Embassy Suites by Hilton San Antonio Brooks Hotel & Spa
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
7610 South New Braunfels, San Antonio, TX 78235 +1-888-897-9207 ~6.81 miles northeast of 78221
  • 3-star Suburban property
  • 7 meeting rooms in property
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From$102
Very Good 4.0 /5 Read Reviews Call BookMore Details
Best Western Plus Elmendorf Hotel in Elmendorf
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
20015 Eagle Ford Way, Elmendorf, TX 78112 +1-888-311-4278 ~6.95 miles east of 78221
  • Affordable Highway property
  • 63 sleeping rooms in hotel
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From$80
Very Good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites San Antonio Brooks Cb
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
8222 City Base Landing, San Antonio, TX 78235 +1-888-469-4795 ~7.27 miles northeast of 78221
  • Midscale Suburban property
  • Access to gym on-site
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From$52
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites San Antonio City Base Landing
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
8202 City Base Landing, San Antonio, TX 78235 +1-888-734-9421 ~7.39 miles northeast of 78221
  • Midscale Suburban property
  • Check in time: 3:00pm
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From$68
Very Good 4.0 /5 Guest Reviews Call BookMore Details
La Quinta Inn by Wyndham San Antonio Brooks City Base
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
3180 Goliad Rd., San Antonio, TX 78223 +1-888-841-5292 ~7.55 miles northeast of 78221
  • Low priced Suburban hotel
  • Airport shuttle available
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From$62
Average 3.0 /5 Guest Reviews Call BookMore Details
Econo Lodge Downtown South
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
606 Division Ave., San Antonio, TX 78214 +1-888-455-5160 ~7.59 miles north of 78221
  • Low-priced property
  • Check in time: 12:00
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From$60
Poor 2.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites San Antonio Brooks City Base - San Antonio
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
3234 Goliad Rd., San Antonio, TX 78223 +1-888-965-8297 ~7.61 miles northeast of 78221
  • Mid-scale Suburban hotel
  • Hotel has 17 suites
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From$61
Very Good 4.0 /5 Review Score Call BookMore Details
Motel 6 San Antonio, TX - Downtown - Alamo Dome - San Antonio
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
748 Hot Wells Blvd., San Antonio, TX 78223 +1-888-906-6358 ~7.76 miles northeast of 78221
  • Two star Downtown property
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From$30
Poor 2.5 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham San Antonio/Alamodome Area
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
723 Hot Wells, San Antonio, TX 78223 +1-888-749-6785 ~7.78 miles northeast of 78221
  • Low priced Downtown hotel
  • Free comp. breakfast
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From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Quality Suites San Antonio in San Antonio
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
3602 SE Military Dr., San Antonio, TX 78223 +1-888-878-9982 ~7.89 miles northeast of 78221
  • Three Star Suburban property
  • Has environment-friendly policy Learn more
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From$49
Average 3.0 /5 Hotel Reviews Call BookMore Details
Econo Lodge Inn & Suites
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
120 Rustleaf Dr., San Antonio, TX 78242 +1-888-389-4485 ~8.76 miles northwest of 78221
  • Inexpensive property
  • Check-in time: 11:00 AM
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From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Econo Lodge Inn & Suites Near Lackland AFB
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
Rustleaf & SW Military Dr., San Antonio, TX 78242 +1-888-389-4121 ~8.78 miles northwest of 78221
  • Low priced hotel
  • 32 rooms in property
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From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Stay Nixon : 423 Blue Star
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
423 Blue Star, San Antonio, TX 78204 +1-888-675-2083 ~9.45 miles north of 78221
  • 4-star Downtown hotel
  • 41 rooms in hotel
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From$99
Average 3.0 /5 Reviews Call BookMore Details
Sonder Southtown Suites
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
111 Probandt St., San Antonio, TX 78204 +1-800-716-8490 ~9.57 miles north of 78221
  • Expensive Downtown property
  • Fitness center on property
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From$75
Average 3.0 /5 Hotel Reviews Call BookMore Details
The Inn at Market Square - San Antonio
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1500 I 35 South Exit 154b Laredo St., San Antonio, TX 78204 +1-800-805-5223 ~9.74 miles north of 78221
  • Cheap Downtown hotel
  • 90 rooms in hotel
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From$35
Poor 2.0 /5 Latest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Braunig Lake - Elmendorf
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
13800 Ih 37 South, Elmendorf, TX 78112 +1-888-965-1860 ~9.89 miles east of 78221
  • Cheap Lake property
  • 62 sleeping rooms in hotel
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From$59
Very Good 4.0 /5 Read Reviews Call BookMore Details
Econo Lodge Inn & Suites Downtown San Antonio Riverwalk Area - San Antonio
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1122 South Laredo St., San Antonio, TX 78204 +1-888-788-5576 ~10.06 miles north of 78221
  • Two-star Downtown property
  • Check-in time: 3:00 pm
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From$30
Not Good 1.5 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham San Antonio/Riverwalk Area - San Antonio
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
302 Roland Ave., San Antonio, TX 78210 +1-888-897-9207 ~10.08 miles north of 78221
  • Inexpensive Downtown property
  • Hotel has 28 suites
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Candlewood Suites San Antonio Downtown An Ihg Hotel in San Antonio
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1024 South Laredo St., San Antonio, TX 78204 +1-888-311-4278 ~10.08 miles north of 78221
  • Low Cost Downtown hotel
  • 96 suites in hotel
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From$72
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn Downtown - near Market Square
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1025 South Frio St., San Antonio, TX 78207 +1-888-469-4795 ~10.12 miles north of 78221
  • Cheap Downtown hotel
  • 31 suites in property
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From$60
Very Good 4.0 /5 Reviews Call BookMore Details
Best Western Alamo Suites - San Antonio
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1002 South Laredo St., San Antonio, TX 78204 +1-888-734-9421 ~10.15 miles north of 78221
  • 3-star Downtown property
  • Hotel has 3 floors
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From$75
Very Good 4.0 /5 Review Score Call BookMore Details
Best Western Plus Roland Inn & Suites - San Antonio
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
333 Roland Ave., San Antonio, TX 78210 +1-888-841-5292 ~10.20 miles north of 78221
  • Affordable property
  • Free complimentary breakfast
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From$59
Very Good 4.0 /5 Recent Reviews Call BookMore Details
River Inn Motel
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
909 South Frio St., San Antonio, TX 78207 +1-888-455-5160 ~10.20 miles north of 78221
  • 2-star Downtown hotel
  • Check in time: 3:00PM
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From$60
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites San Antonio Dtwn Market Area in San Antonio
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
102 El Paso St., San Antonio, TX 78204 +1-888-965-8297 ~10.27 miles north of 78221
  • Low priced Downtown hotel
  • Fitness + Health Center
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From$65
Very Good 4.0 /5 Review Score Call BookMore Details
Residence Inn by Marriott San Antonio Downtown Market Square - San Antonio
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
628 South Santa Rosa Ave., San Antonio, TX 78204 +1-888-906-6358 ~10.39 miles north of 78221
  • Mid-scale Downtown hotel
  • 110 rooms in hotel
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From$109
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Sonder La Villita
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
633 South St. Mary's St., San Antonio, TX 78205 +1-888-749-6785 ~10.41 miles north of 78221
  • 4 star Downtown hotel
  • Check-in: 4:00 PM
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From$75
Average 3.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott San Antonio Market Square - San Antonio
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
620 South Santa Rosa Ave., San Antonio, TX 78204 +1-888-878-9982 ~10.41 miles north of 78221
  • 3 star Downtown property
  • Has environment-friendly policy Read more
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From$80
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Plaza San Antonio Hotel & Spa, Autograph Collection : 555 South Alamo St.
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
555 South Alamo St., San Antonio, TX 78205 +1-888-389-4485 ~10.44 miles north of 78221
  • High end Downtown hotel
  • Fitness / Gym is on-site
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From$121
Very Good 4.0 /5 Guest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham San Antonio Downtown : 100 West Cesar Chavez Blvd.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
100 West Cesar Chavez Blvd., San Antonio, TX 78204 +1-888-389-4121 ~10.44 miles north of 78221
  • 3-star Downtown hotel
  • Hotel has 4 meeting rooms
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From$89
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hyatt Place San Antonio Riverwalk
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
601 South St. Mary's St., San Antonio, TX 78205 +1-888-675-2083 ~10.46 miles north of 78221
  • 3 star Downtown property
  • Complimentary breakfast is offered
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From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites San Antonio-Downtown/Market Square
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
411 South Flores St., San Antonio, TX 78204 +1-800-716-8490 ~10.47 miles north of 78221
  • Three Star Downtown hotel
  • 108 sleeping rooms in hotel
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From$120
Average 3.0 /5 Latest Reviews Call BookMore Details
Inn on the Riverwalk : 129 Woodward Place
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
129 Woodward Place, San Antonio, TX 78204 +1-800-805-5223 ~10.48 miles north of 78221
  • Affordable Downtown hotel
  • Hotel has 3 floors
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From$119
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott San Antonio Downtown/Market Square
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
600 South Santa Rosa Ave., San Antonio, TX 78204 +1-888-965-1860 ~10.48 miles north of 78221
  • Affordable Downtown property
  • 3 floors in hotel
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From$119
Very Good 4.0 /5 Reviews Call BookMore Details
Holiday Inn San Antonio - Dwtn - Market Sq, an IHG Hotel
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
318 West César East Chávez Blvd., San Antonio, TX 78204 +1-888-788-5576 ~10.49 miles north of 78221
  • Affordable property
  • Check in: 4:00pm
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Springhill Suites by Marriott San Antonio Downtown / Riverwalk Ar : 524 South St. Mary's St.
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
524 South St. Mary's St., San Antonio, TX 78205 +1-888-897-9207 ~10.50 miles north of 78221
  • Affordable Convention Center property
  • 116 suites in hotel
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From$80
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Downtown Market Square
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
318 West Durango Blvd., San Antonio, TX 78204 +1-888-311-4278 ~10.51 miles north of 78221
  • Three Star Downtown property
  • 313 rooms in hotel
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From$74
Average 3.5 /5 Recent Reviews Call BookMore Details
Holiday Inn San Antonio - Dwtn - Market Sq, an IHG Hotel
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
318 West Cesar East Chavez Blvd., San Antonio, TX 78204 +1-888-469-4795 ~10.52 miles north of 78221
  • Mid-scale Downtown hotel
  • 8 conference rooms in property
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From$56
Very Good 4.0 /5 Review Score Call BookMore Details
Club Wyndham La Cascada : 226 Dwyer Ave.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
226 Dwyer Ave., San Antonio, TX 78204 +1-888-734-9421 ~10.54 miles north of 78221
  • High end Downtown property
  • Check-in time: 4
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From$85
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
The Fairmount Hotel
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
401 South Alamo, San Antonio, TX 78205 +1-888-841-5292 ~10.56 miles north of 78221
  • 4 star Downtown property
  • Hotel has 2 meeting rooms
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From$149
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Doubletree by Hilton San Antonio Downtown - San Antonio
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
502 West César East Chávez Blvd., San Antonio, TX 78207 +1-888-455-5160 ~10.57 miles north of 78221
  • Three Star Downtown property
  • Hotel has 13 meeting rooms
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From$75
Average 3.0 /5 Read Reviews Call BookMore Details
O´Brien Historic Hotel in San Antonio
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
116 Navarrro St., San Antonio, TX 78205 +1-888-965-8297 ~10.59 miles north of 78221
  • 3 star Downtown hotel
  • Free breakfast
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From$77
Very Good 4.0 /5 Review Score Call BookMore Details
Embassy Suites San Antonio Brooks
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
502 West Cesar East Chavez, San Antonio, TX 78207 +1-888-906-6358 ~10.60 miles north of 78221
  • 3-star Downtown hotel
  • Fitness + Health Center
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From$89
Average 3.5 /5 Latest Reviews Call BookMore Details
Stay Express Inn & Suites
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
100 Valley Hi Dr., San Antonio, TX 78227 +1-888-749-6785 ~10.63 miles northwest of 78221
  • Cheap Suburban property
  • 62 sleeping rooms in hotel
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From$37
Poor 2.0 /5 Reviews Call BookMore Details
Staybridge Suites San Antonio Downtown Conv Ctr, an IHG Hotel : 123 Hoefgen Ave.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
123 Hoefgen Ave., San Antonio, TX 78205 +1-888-878-9982 ~10.66 miles north of 78221
  • Three Star Downtown hotel
  • 138 suites in property
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From$105
Very Good 4.0 /5 Read Reviews Call BookMore Details
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