Hotels in 78221 - San Antonio TX

Only hotels in 78221 zip code are listed below. Search for cheap and discount hotel rates in San Antonio, TX for your upcoming leisure or conference / group travel. We list the best 78221 hotels and motels so you can review the San Antonio hotel list below to find the perfect lodging. Hotels in Bexar county and area code 210 are also listed.


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78221 Hotels & Accommodations

Image of Holiday Inn Express Sa SouthHoliday Inn Express Sa South in San Antonio
+1-800-230-4134
$70+

1225 Chaveneaux Rd., San Antonio, TX 78221
  • Mid-scale hotel
  • Hotel has 3 floors
Exterior of Value Place San Antonio Tx (South)Value Place San Antonio Tx (South)
+1-800-997-5148
$31+

7958 South Ih 35, San Antonio, TX 78224
  • Economical Highway hotel
  • 4 floors in hotel
~5.58 Miles from 78221
Image of La Quinta Inn South Park #0510La Quinta Inn South Park #0510 - San Antonio
+1-800-997-5149
$59+

7202 South Pan Am Expressway, San Antonio, TX 78224~5.93 Miles from 78221
Photo of Holiday Inn Express & Suites San Antonio Se MilitaHoliday Inn Express & Suites San Antonio Se Milita
+1-800-230-4134
$75+

8222 City Base Lndg, San Antonio, TX 78235
  • Three Star Highway hotel
  • Fitness + Health Center
~7.27 Miles from 78221
Photo of La Quinta InnLa Quinta Inn
+1-800-997-5148
$109+

3180 Goliad Rd., San Antonio, TX 78223
  • 3.5/5, Average Review Score
  • 2-star Suburban property
  • Hotel has 115 rooms
~7.55 Miles from 78221
Holiday Inn Express South : 606 Division Ave.
+1-800-997-5149
$75+

606 Division Ave., San Antonio, TX 78214~7.59 Miles from 78221
Photo of Elmendorf LodgeElmendorf Lodge in San Antonio
+1-800-230-4134
$19+

4900 Via La Circula, San Antonio, TX 78223
  • 3 star Rural hotel
  • Check in: 3:00 pm
~7.74 Miles from 78221
Image of Motel 6Motel 6
+1-800-997-5148
$30+

748 Hot Wells Blvd., San Antonio, TX 78223
  • Economy Downtown hotel
  • 3 floors in hotel
~7.76 Miles from 78221
Super 8 San Antonio Near Alamodome : 723 Hotwells Blvd.
+1-800-997-5149
$54+

723 Hotwells Blvd., San Antonio, TX 78223
  • Inexpensive Downtown hotel
  • Free comp. breakfast
~7.78 Miles from 78221
Roosevelt Inn Motel : 2122 Roosevelt Ave.
+1-800-230-4134
$55+

2122 Roosevelt Ave., San Antonio, TX 78210
  • Cheap Highway property
  • 62 sleeping rooms in hotel
~8.01 Miles from 78221
Matador Motel - San Antonio
+1-800-997-5148
$30+

3800 South Zarzamora, San Antonio, TX 78225
  • 4.5/5, Very Good Reviews
  • Cheap Suburban property
  • 26 rooms in hotel
~8.20 Miles from 78221
Days Inn Downtown Riverwalk Area
+1-800-997-5149
$34+

1500 I 35 South Exit 154b Laredo St., San Antonio, TX 78204
  • 1.5/5, Terrible Read Reviews
  • Inexpensive Downtown hotel
  • Free complimentary breakfast
~9.79 Miles from 78221
Ramada Limited in San Antonio
+1-800-230-4134
$30+

1122 South Laredo St., San Antonio, TX 78204
  • 1.5/5, Terrible Recent Reviews
  • Cheap Downtown property
  • Fitness center on property
~10.06 Miles from 78221
Gardenia Inn in San Antonio
+1-800-997-5148
$70+

307 Beauregard St., San Antonio, TX 78204~10.11 Miles from 78221
Candlewood Suites
+1-800-997-5149
$64+

1024 South Laredo St., San Antonio, TX 78204
  • 4.0/5, Very Good Guest Reviews
  • Economy Downtown hotel
  • 96 suites in hotel
~10.11 Miles from 78221
Super 8
+1-800-230-4134
$59+

302 Roland Ave., San Antonio, TX 78210
  • 4.0/5, Very Good Read Reviews
  • Low priced Downtown hotel
  • Free breakfast
~10.13 Miles from 78221
Manguson Hotel : 1025 South Frio St.
+1-800-997-5148
$35+

1025 South Frio St., San Antonio, TX 78207
  • 1.5/5, Terrible Review Score
  • Cheap Downtown property
  • Hotel has 3 floors
~10.14 Miles from 78221
Best Western Alamo Suites
+1-800-997-5149
$75+

1002 South Laredo St., San Antonio, TX 78204
  • 4.0/5, Very Good Hotel Reviews
  • Midscale Downtown hotel
  • Free comp. breakfast
~10.14 Miles from 78221
Holiday Inn Express Market Area San Antonio - San Antonio
+1-800-230-4134
$69+

102 El Paso St., San Antonio, TX 78204
  • Three Star Downtown hotel
  • 78 sleeping rooms in hotel
~10.27 Miles from 78221
Fairfield Inn & Suites Downtown Market Square
+1-800-997-5148
$71+

620 South Santa Rosa, San Antonio, TX 78204
  • 4.0/5, Very Good Guest Reviews
  • Low priced Downtown hotel
  • 2 meeting rooms in property
~10.40 Miles from 78221
Residence Inn by Marriott Downtown Market Square
+1-800-997-5149
$79+

628 South Santa Rosa, San Antonio, TX 78204
  • 4.0/5, Very Good Hotel Reviews
  • Three Star Downtown property
  • Hotel has 3 floors
~10.42 Miles from 78221
Marriott Plaza San Antonio - San Antonio
+1-800-230-4134
$115+

555 South Alamo, San Antonio, TX 78205
  • 4.0/5, Very Good Latest Reviews
  • Four-star Downtown property
  • 15 meeting rooms in hotel
~10.44 Miles from 78221
Courtyard Downtown Market Square : 600 South Santa Rosa
+1-800-997-5148
$129+

600 South Santa Rosa, San Antonio, TX 78204
  • 4.0/5, Very Good Hotel Reviews
  • Mid-scale Downtown property
  • Check-in time: 3:00PM
~10.44 Miles from 78221
La Quinta Inn & Suites Downtown : 100 West Durango St.
+1-800-997-5149
$93+

100 West Durango St., San Antonio, TX 78204
  • 4.0/5, Very Good Reviews
  • 3 star Downtown property
  • 11 suites in hotel
~10.45 Miles from 78221
Hyatt Place San Antonio Riverwalk
+1-800-230-4134
$119+

601 South St. Mary's St., San Antonio, TX 78205
  • Affordable Downtown hotel
  • 3 meeting rooms in property
~10.45 Miles from 78221
Hampton Inn & Suites Downtown / Market Square
+1-800-997-5148
$104+

411 South Flores St., San Antonio, TX 78205
  • Mid-scale Downtown property
  • Free comp. breakfast
~10.48 Miles from 78221
Inn on the Riverwalk - San Antonio
+1-800-997-5149
$79+

129 Woodward Place, San Antonio, TX 78204
  • 4.0/5, Very Good Recent Reviews
  • Affordable Downtown hotel
  • 3 suites in property
~10.49 Miles from 78221
Springhill Suites by Marriott San Antonio Downtown
+1-800-230-4134
$94+

524 South St. Mary's St., San Antonio, TX 78205
  • Mid-scale Downtown hotel
  • Check in: 3:00pm
~10.50 Miles from 78221
Holiday Inn San Antonio Downtown Market Square in San Antonio
+1-800-997-5148
$75+

318 West Cesar Chavez Blvd., San Antonio, TX 78204
  • 3.5/5, Average Recent Reviews
  • Affordable Downtown hotel
  • Fitness center on property
~10.51 Miles from 78221
Holiday Inn San Antonio Downtown Market Square
+1-800-997-5149
$55+

318 West Durango Blvd., San Antonio, TX 78204
  • Midscale Downtown property
  • 2 suites in property
~10.51 Miles from 78221
La Cascada
+1-800-230-4134
$60+

226 Dwyer Ave., San Antonio, TX 78204
  • Three Star Downtown hotel
  • 10 floors in property
~10.54 Miles from 78221
The Fairmount Hotel
+1-800-997-5148
$149+

401 South Alamo, San Antonio, TX 78205
  • 3.5/5, Average Hotel Reviews
  • Mid-scale Downtown property
  • Hotel has 2 meeting rooms
~10.56 Miles from 78221
Doubletree by Hilton San Antonio Downtown
+1-800-997-5149
$89+

502 West Cesar East Chavez Blvd., San Antonio, TX 78207
  • 3.5/5, Average Hotel Reviews
  • 3-star Downtown property
  • Check in: 3 pm
~10.59 Miles from 78221
O'brien Hotel An Ascend Collection Hotel : 116 Navarro St.
+1-800-230-4134
$69+

116 Navarro St., San Antonio, TX 78205
  • 4.0/5, Very Good Guest Reviews
  • Affordable Downtown hotel
  • Access to gym on-site
~10.60 Miles from 78221
Stay Express Inn & Suites
+1-800-997-5148
$29+

100 Valley Hi Dr., San Antonio, TX 78227
  • 2.0/5, Poor Guest Reviews
  • Cheap Suburban property
  • Check-in: 1:00 PM
~10.63 Miles from 78221
Staybridge Suites Downtown Convention Center : 123 Hoefgen Ave.
+1-800-997-5149
$95+

123 Hoefgen Ave., San Antonio, TX 78205
  • 3-star Downtown property
  • Fitness center on property
~10.66 Miles from 78221
Riverwalk Plaza Hotel & Suites - San Antonio
+1-800-230-4134
$78+

100 Villita St., San Antonio, TX 78205
  • 3.5/5, Average Guest Reviews
  • Mid-scale Downtown hotel
  • Fitness center on property
~10.67 Miles from 78221
Hilton Palacio Del Rio : 200 South Alamo St.
+1-800-997-5148
$139+

200 South Alamo St., San Antonio, TX 78205
  • 4.0/5, Very Good Read Reviews
  • Four-star Downtown property
  • 31 conference rooms in property
~10.68 Miles from 78221
La Hacienda Inn Alamodome / Riverwalk in San Antonio
+1-800-997-5149
$45+

1524 East Commerce St., San Antonio, TX 78205
  • Cheap Convention Center hotel
  • 19 sleeping rooms in hotel
~10.70 Miles from 78221
Grand Hyatt San Antonio - San Antonio
+1-800-230-4134
$129+

600 East Market St., San Antonio, TX 78205
  • 4.0/5, Very Good Recent Reviews
  • High-end Downtown hotel
  • 24 floors in hotel
~10.70 Miles from 78221
Cityview Inn & Suites Sunset Station
+1-800-997-5148
$70+

1306 East Commerce, San Antonio, TX 78205
  • 4.0/5, Very Good Latest Reviews
  • Low Cost Downtown property
  • 4 suites in property
~10.72 Miles from 78221
Hotel Contessa Riverwalk Luxury Suites
+1-800-997-5149
$336+

306 West Market St., San Antonio, TX 78205
  • 4.5/5, Very Good Reviews
  • High end Downtown hotel
  • Check in time: 4:00 PM
~10.72 Miles from 78221
La Quinta Market Square in San Antonio
+1-800-230-4134
$84+

900 Dolorosa, San Antonio, TX 78207~10.73 Miles from 78221
Homewood Suites by Hilton Riverwalk
+1-800-997-5148
$159+

432 West Market St., San Antonio, TX 78205
  • 4.0/5, Very Good Review Score
  • 3-star Downtown hotel
  • Comp. Breakfast
~10.73 Miles from 78221
Best Western Plus Sunset Suites Riverwalk : 1103 East Commerce
+1-800-997-5149
$65+

1103 East Commerce, San Antonio, TX 78205
  • 4.5/5, Very Good Latest Reviews
  • Affordable Downtown hotel
  • Check in: 3:00 pm
~10.74 Miles from 78221
Westin Riverwalk : 420 West Market
+1-800-230-4134
$300+

420 West Market, San Antonio, TX 78205
  • High end Downtown hotel
  • Hotel has 10 meeting rooms
~10.74 Miles from 78221
The Westin Riverwalk
+1-800-997-5148
$240+

420 West Market St., San Antonio, TX 78205
  • 4.5/5, Very Good Review Score
  • 4-star Downtown hotel
  • Check in time: 3:00pm
~10.74 Miles from 78221
Motel 6 Market Square
+1-800-997-5149
$39+

211 North Pecos St., San Antonio, TX 78207
  • Cheap property
  • 2 floors in hotel
~10.74 Miles from 78221
Holiday Inn Express Suites Rivercenter
+1-800-230-4134
$85+

1309 East Commerce St., San Antonio, TX 78205
  • 4.0/5, Very Good Hotel Reviews
  • Mid-scale Downtown property
  • Free breakfast
~10.75 Miles from 78221
Drury Plaza River Walk San Antonio - San Antonio
+1-800-997-5148
$134+

105 South St. Mary's St., San Antonio, TX 78205
  • Three Star Downtown hotel
  • Hotel has 23 floors
~10.76 Miles from 78221



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