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78221 Hotels, Motels & Accommodations

Holiday Inn Express & Suites San Antonio South : 11400 SE Loop 410 11400 SE Loop 410, San Antonio, TX 78221
  • 3 star Suburban hotel
  • Hotel has 3 floors
From$57
Average 3.5 /5 Reviews Call BookMore Details
Best Western Plus Palo Alto Inn & Suites 12507 SW Loop 410, San Antonio, TX 78224 ~4.13 miles northwest of 78221
  • Midscale hotel
  • Hotel has 32 suites
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn San Antonio at Palo Alto 9403 Poteet Jourdanton Freeway, San Antonio, TX 78224 ~4.59 miles northwest of 78221
  • Inexpensive Downtown hotel
  • Check-in: 11:00 AM
From$60
Average 3.0 /5 Review Score Call BookMore Details
Woodspring Suites San Antonio South - San Antonio 7958 Interstate 35 Access Rd., San Antonio, TX 78224 ~4.76 miles north of 78221
  • Low Cost property
  • 121 rooms in hotel
Value Place San Antonio Tx (South) : 7958 South Ih 35 7958 South Ih 35, San Antonio, TX 78224 ~5.58 miles north of 78221
  • Cheap Highway property
  • Hotel has 4 floors
  • Rooms are not good
  • Excellent value
La Quinta Inn South Park #0510 - San Antonio 7202 South Pan Am Expressway, San Antonio, TX 78224 ~5.93 miles north of 78221
  • Midscale Highway property
  • Check-in: 3:00 PM
  • Most guests liked the proximity to sightseeing
  • Restroom was filthy
From$51
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 San Antonio South : 7950 South Panam Expy 7950 South Panam Expy, San Antonio, TX 78224 ~6.31 miles north of 78221
  • Economy hotel
  • 3 floors in property
From$60
Average 3.0 /5 Reviews Call BookMore Details
Embassy Suites by Hilton San Antonio Brooks Hotel & Spa : 7610 South New Braunfels 7610 South New Braunfels, San Antonio, TX 78235 ~6.81 miles northeast of 78221
  • Affordable Suburban hotel
  • Check-in: 4:00 PM
From$102
Very Good 4.5 /5 Review Score Call BookMore Details
Best Western Plus Elmendorf Hotel 20015 Eagle Ford Way, Elmendorf, TX 78112 ~6.95 miles east of 78221
  • 3-star Highway hotel
  • Comp. Breakfast
From$80
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites San Antonio Brooks Cb in San Antonio 8222 City Base Lndg, San Antonio, TX 78235 ~7.27 miles northeast of 78221
  • 3-star Suburban hotel
  • 4 floors in hotel
From$57
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn & Suites Braunig Lake 13800 Ih 37 South, Elmendorf, TX 78112 ~7.27 miles east of 78221
  • Affordable property
From$80
Average 3.5 /5 Read Reviews Call BookMore Details
Hampton Inn San Antonio Brooks City Base - San Antonio 8202 City Base Landing, San Antonio, TX 78235 ~7.39 miles northeast of 78221
  • 3 star property
  • 100 rooms in hotel
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
La Quinta Inn 3180 Goliad Rd., San Antonio, TX 78223 ~7.55 miles northeast of 78221
  • 2-star Suburban property
  • Free comp. breakfast
  • Rooms could be larger
  • New Holiday Inn express
From$62
Average 3.5 /5 Hotel Reviews Call BookMore Details
Econo Lodge Downtown South - San Antonio 606 Division Ave., San Antonio, TX 78214 ~7.59 miles north of 78221
  • Two star hotel
  • Check-in: 12:00
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites Brooks City Base 3234 Goliad Rd., San Antonio, TX 78223 ~7.61 miles northeast of 78221
  • Midscale Suburban property
  • Hotel has 3 floors
From$61
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Elmendorf Lodge - San Antonio
+1-888-305-3366
4900 Via La Circula, San Antonio, TX 78223 ~7.74 miles east of 78221
  • Three Star Rural hotel
  • 24 suites in hotel
Motel 6 748 Hot Wells Blvd., San Antonio, TX 78223 ~7.76 miles northeast of 78221
  • Two-star Downtown property
  • 3 floors in hotel
From$30
Poor 2.5 /5 Reviews Call BookMore Details
Super 8 San Antonio Near Alamodome - San Antonio 723 Hotwells Blvd., San Antonio, TX 78223 ~7.78 miles northeast of 78221
  • Low priced Downtown hotel
  • Free comp. breakfast
  • Comfortable bed
  • Clean
From$59
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Suites San Antonio 3602 SE Military Dr., San Antonio, TX 78223 ~7.89 miles northeast of 78221
  • Inexpensive Suburban hotel
  • 25 suites in property
From$49
Average 3.5 /5 Hotel Reviews Call BookMore Details
Roosevelt Inn Motel : 2122 Roosevelt Ave.
+1-866-429-5787
2122 Roosevelt Ave., San Antonio, TX 78210 ~8.01 miles north of 78221
  • Low Cost Highway hotel
  • 62 rooms in property
Travelodge San Antonio Lackland a F B : 120 Rustleaf Dr. 120 Rustleaf Dr., San Antonio, TX 78242 ~8.76 miles northwest of 78221
  • Two-star hotel
  • Check-in: 11:00 AM
From$60
Average 3.0 /5 Review Score Call BookMore Details
The Inn at Market Square Downtown - San Antonio 1500 I 35 South Exit 154b Laredo St., San Antonio, TX 78204 ~9.74 miles north of 78221
  • Low Cost Downtown hotel
  • 90 sleeping rooms in hotel
  • Including the breakfast buffet
  • About half of guests were satisfied with the proximity to sightseeing
Travelodge Downtown San Antonio - San Antonio 1122 South Laredo St., San Antonio, TX 78204 ~10.05 miles north of 78221
  • 2 star Downtown property
  • Complimentary breakfast is offered
Best Western Plus Roland Inn & Suites 333 Roland Ave., San Antonio, TX 78210 ~10.10 miles north of 78221
  • Mid-scale hotel
  • Check in time: 03:00
From$80
Excellent 5.0 /5 Reviews Call BookMore Details
Eva's Escape at the Gardenia Inn - San Antonio 307 Beauregard St., San Antonio, TX 78204 ~10.11 miles north of 78221
  • Midscale Downtown hotel
  • Hotel has 3 floors
  • Hospitality was fantastic
  • Beautiful property
From$95
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Candlewood Suites 1024 South Laredo St., San Antonio, TX 78204 ~10.11 miles north of 78221
  • 2 star Downtown property
  • Hotel has 2 meeting rooms
  • Hotel was very clean
  • Most guests found the kitchenette to be good
From$59
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Knights Inn San Antonio S Frio Street 1025 South Frio St., San Antonio, TX 78207 ~10.12 miles north of 78221
  • Economical Downtown property
  • Free complimentary breakfast
From$40
Not Good 1.5 /5 Guest Reviews Call BookMore Details
Super 8
+1-888-690-5281
302 Roland Ave., San Antonio, TX 78210 ~10.13 miles north of 78221
  • Economical Downtown hotel
  • 55 rooms in property
From$59
Average 3.5 /5 Review Score Call BookMore Details
Best Western Alamo Suites - San Antonio 1002 South Laredo St., San Antonio, TX 78204 ~10.15 miles north of 78221
  • Mid-scale Downtown hotel
  • Gym / Fitness Center Available
From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Rodeway Inn Downtown
+1-888-305-3366
909 South Frio St., San Antonio, TX 78207 ~10.20 miles north of 78221
  • Two star hotel
  • 20 rooms in hotel
Holiday Inn Express & Suites San Antonio Dtwn Market Area 102 El Paso St., San Antonio, TX 78204 ~10.27 miles north of 78221
  • Cheap Downtown hotel
  • 78 rooms in property
From$60
Average 3.5 /5 Review Score Call BookMore Details
Residence Inn San Antonio Market Square : 628 South Santa Rosa Ave. 628 South Santa Rosa Ave., San Antonio, TX 78204 ~10.39 miles north of 78221
  • Mid-scale Downtown hotel
  • Gym / Fitness Center Available
From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites Downtown / Marketsquare 620 South Santa Rosa Ave., San Antonio, TX 78204 ~10.42 miles north of 78221
  • 3-star Downtown hotel
  • 36 suites in hotel
  • Good for sightseeing with nearby parking areas
  • The majority of guests were happy with the price of the breakfast
From$89
Very Good 4.0 /5 Review Score Call BookMore Details
Marriott Plaza San Antonio in San Antonio 555 South Alamo, San Antonio, TX 78205 ~10.44 miles north of 78221
  • Four star Downtown hotel
  • Check in: 4:00 PM
  • Close to River Walk
  • Fantastic service
From$121
Very Good 4.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites San Antonio Downtown : 100 West Cesar Chavez Blvd. 100 West Cesar Chavez Blvd., San Antonio, TX 78204 ~10.44 miles north of 78221
  • 3-star Downtown property
  • 6 floors in property
From$89
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hyatt Place San Antonio Riverwalk
+1-888-690-5247
601 South St. Mary's St., San Antonio, TX 78205 ~10.45 miles north of 78221
  • Affordable Downtown hotel
  • Has environment-friendly policy Read more
  • Elevator was still broken
  • Near wonderful eating establishments
From$119
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites San Antonio Downtown / Market Square in San Antonio 411 South Flores St., San Antonio, TX 78204 ~10.47 miles north of 78221
  • Midscale Downtown hotel
  • Free comp. breakfast
  • Breakfast is good
  • Good location
From$120
Very Good 4.0 /5 Reviews Call BookMore Details
Inn on the Riverwalk in San Antonio 129 Woodward Place, San Antonio, TX 78204 ~10.48 miles north of 78221
  • Mid-scale Downtown property
  • Free breakfast available
Courtyard by Marriott San Antonio Downtown / Market Square - San Antonio
+1-888-283-3404
600 South Santa Rosa Ave., San Antonio, TX 78204 ~10.48 miles north of 78221
  • Affordable Downtown property
  • 3 floors in hotel
From$119
Very Good 4.0 /5 Reviews Call BookMore Details
Springhill Suites by Marriott San Antonio Downtown / Riverwalk Ar : 524 South St. Mary's St. 524 South St. Mary's St., San Antonio, TX 78205 ~10.50 miles north of 78221
  • 3 star Downtown hotel
  • Hotel has an eco-friendly policy See more
From$96
Very Good 4.0 /5 Reviews Call BookMore Details
Holiday Inn San Antonio Dwtn Market Sq : 318 West Cesar East Chavez Blvd. 318 West Cesar East Chavez Blvd., San Antonio, TX 78204 ~10.52 miles north of 78221
  • Midscale Downtown property
  • Check-in time: 3:00
  • Air conditioning was criticized by 78%
  • Terrible amenities
From$77
Average 3.5 /5 Hotel Reviews Call BookMore Details
La Cascada Resort 226 Dwyer Ave., San Antonio, TX 78204 ~10.54 miles north of 78221
  • 4 star Downtown hotel
  • 97 suites in hotel
From$85
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
The Fairmount Hotel
+1-888-690-5247
401 South Alamo, San Antonio, TX 78205 ~10.56 miles north of 78221
  • 4-star Downtown hotel
  • 2 meeting rooms in property
  • Quite clean
  • Great reception
From$149
Average 3.5 /5 Guest Reviews Call BookMore Details
The O'brien Historic Hotel Riverwalk - San Antonio 116 Navarrro St., San Antonio, TX 78205 ~10.59 miles north of 78221
  • 3-star Downtown property
  • Comp. Breakfast
From$77
Very Good 4.0 /5 Reviews Call BookMore Details
Doubletree by Hilton San Antonio Downtown : 502 West Cesar East Chavez 502 West Cesar East Chavez, San Antonio, TX 78207 ~10.60 miles north of 78221
  • Mid-scale Downtown property
  • 20 suites in property
  • Lovely bar service, according to 100%
  • Room cleanliness is acceptable
From$89
Average 3.5 /5 Recent Reviews Call BookMore Details
Stay Express Inn & Suites
+1-888-283-3404
100 Valley Hi Dr., San Antonio, TX 78227 ~10.63 miles northwest of 78221
  • Low-priced Suburban property
  • Free comp. breakfast
  • Almost all guests said rooms were dirty
  • Fantastic staff
Staybridge Suites Downtown Convention Center 123 Hoefgen Ave., San Antonio, TX 78205 ~10.66 miles north of 78221
  • Midscale Downtown property
  • Hotel has 2 meeting rooms
  • Staff was excellent
  • Tasty breakfast
From$105
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Riverwalk Plaza Hotel & Suites in San Antonio 100 Villita St., San Antonio, TX 78205 ~10.67 miles north of 78221
  • Three Star Downtown property
  • 8 suites in property
  • Great desserts & fruits
  • Almost all guests thought the building wasn't nice
From$75
Average 3.5 /5 Read Reviews Call BookMore Details
Hilton Palacio Del Rio : 200 South Alamo 200 South Alamo, San Antonio, TX 78205 ~10.68 miles north of 78221
  • Four star Downtown hotel
  • 10 suites in hotel
From$149
Very Good 4.5 /5 Guest Reviews Call BookMore Details
La Hacienda Inn Alamodome / Riverwalk : 1524 East Commerce St. 1524 East Commerce St., San Antonio, TX 78205 ~10.70 miles north of 78221
  • Low priced Convention Center property
  • 19 sleeping rooms in hotel
From$71
Very Good 4.0 /5 Read Reviews Call BookMore Details

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