63780 Hotels/Accommodations

Candlewood Suites Cape Girardeau, an IHG Hotel
+1-888-389-4121
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 +1-888-389-4121 ~9.95 miles northwest of 63780
  • Low priced Highway hotel
  • 85 rooms in hotel
From$69
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown in Cape Girardeau
+1-888-675-2083
400 Broadway St., Cape Girardeau, MO 63701 +1-888-675-2083 ~10.05 miles north of 63780
  • Mid-scale Downtown hotel
  • Gym is available on property
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East - Cape Girardeau
+1-800-716-8490
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 +1-800-716-8490 ~10.67 miles northwest of 63780
  • Three Star Highway hotel
  • 86 sleeping rooms in hotel
From$80
Excellent 5.0 /5 Hotel Reviews Call BookMore Details
Victorian Inn & Suites in Cape Girardeau
+1-800-805-5223
3256 William St., Cape Girardeau, MO 63703 +1-800-805-5223 ~10.74 miles northwest of 63780
  • 3-star Golf Course property
  • Hotel has 133 rooms
From$79
Average 3.0 /5 Reviews Call BookMore Details
Auburn Place Hotel & Suites - Cape Girardeau
+1-888-965-1860
3265 Williams St., Cape Girardeau, MO 63702 +1-888-965-1860 ~10.74 miles northwest of 63780
  • Midscale Highway property
  • Hotel has 2 floors
From$58
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55
+1-888-788-5576
3253 William St., Cape Girardeau, MO 63701 +1-888-788-5576 ~10.77 miles northwest of 63780
  • Mid-scale hotel
  • Hotel has 102 suites
From$80
Very Good 4.5 /5 Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center - Cape Girardeau
+1-888-897-9207
3248 William St., Cape Girardeau, MO 63701 +1-888-897-9207 ~10.83 miles northwest of 63780
  • 2-star Highway hotel
  • Free comp. breakfast
From$66
Very Good 4.0 /5 Read Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West
+1-888-311-4278
103 Cape West Pkwy., Cape Girardeau, MO 63701 +1-888-311-4278 ~10.84 miles northwest of 63780
  • 2-star hotel
  • Has environment-friendly policy See policy
From$59
Average 3.0 /5 Reviews Call BookMore Details
Drury Suites Cape Girardeau
+1-888-469-4795
3303 Campster Dr., Cape Girardeau, MO 63701 +1-888-469-4795 ~10.95 miles northwest of 63780
  • Affordable Highway property
  • Gym is available on property
From$85
Very Good 4.5 /5 Read Reviews Call BookMore Details
Drury Lodge in Cape Girardeau
+1-888-734-9421
104 South Vantage Dr., Cape Girardeau, MO 63701 +1-888-734-9421 ~11.11 miles northwest of 63780
  • Mid-scale Highway property
  • Free complimentary breakfast
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau - Cape Girardeau
+1-888-841-5292
3351 Percy Dr., Cape Girardeau, MO 63701 +1-888-841-5292 ~11.13 miles northwest of 63780
  • 3 star hotel
  • 168 sleeping rooms in hotel
From$59
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn
+1-888-455-5160
2011 North Kingshighway St., Cape Girardeau, MO 63701 +1-888-455-5160 ~13.06 miles northwest of 63780
  • Two star hotel
  • Free breakfast
From$60
Very Good 4.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau : 3003 South Old Orchard Rd.
+1-888-965-8297
3003 South Old Orchard Rd., Jackson, MO 63755 +1-888-965-8297 ~14.80 miles northwest of 63780
  • Midscale Highway hotel
  • 9 suites in property
From$85
Very Good 4.0 /5 Review Score Call BookMore Details
Comfort Suites Jackson-Cape Girardeau in Jackson
+1-888-906-6358
2904 Old Orchard Rd., Jackson, MO 63755 +1-888-906-6358 ~14.91 miles northwest of 63780
  • Three Star Highway property
  • 64 rooms in hotel
From$65
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn Cairo I-57
+1-888-749-6785
13201 Kessler Rd., Cairo, IL 62914 +1-888-749-6785 ~17.88 miles east of 63780
  • Three Star Highway hotel
  • 38 rooms in hotel
Super 8 by Wyndham Charleston MO : 310 South Story
+1-888-878-9982
310 South Story, Charleston, MO 63834 +1-888-878-9982 ~19.03 miles southeast of 63780
  • Low Cost Highway property
  • 60 rooms in property
From$42
Average 3.5 /5 Guest Reviews Call BookMore Details
Motel 6 Sikeston Mo
+1-888-389-4485
110 South Interstate Dr., SIKESTON, MO 63801 +1-888-389-4485 ~19.03 miles south of 63780
  • Two-star property
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Best Western Plus Sikeston in Sikeston
+1-888-389-4121
120 South Interstate Dr., Sikeston, MO 63801 +1-888-389-4121 ~19.07 miles south of 63780
  • Low priced Highway property
  • Comp. Breakfast
From$43
Very Good 4.0 /5 Review Score Call BookMore Details
Quality Inn - Charleston
+1-888-675-2083
102 Drake St., Charleston, MO 63834 +1-888-675-2083 ~19.09 miles south of 63780
  • 2-star Highway property
  • Hotel has 40 rooms
From$59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds
+1-800-716-8490
128 Cheekwood Lane, Ullin, IL 62992 +1-800-716-8490 ~19.15 miles east of 63780
  • Economy property
  • Check-in: 15:00
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Drury Inn & Suites Sikeston
+1-800-805-5223
2608 East Malone Ave., Sikeston, MO 63801 +1-800-805-5223 ~19.16 miles south of 63780
  • Affordable Highway hotel
  • 14 suites in property
From$104
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Pear Tree Inn Sikeston
+1-888-965-1860
2602 East Malone, Sikeston, MO 63801 +1-888-965-1860 ~19.16 miles south of 63780
  • Mid-scale Suburban hotel
  • 80 rooms in property
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Travel Inn & Suites
+1-888-788-5576
100 Matthews Lane, Sikeston, MO 63801 +1-888-788-5576 ~19.20 miles south of 63780
  • Affordable Highway property
  • 2 floors in hotel
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Inn
+1-888-897-9207
109 Matthews Lane, Sikeston, MO 63801 +1-888-897-9207 ~19.21 miles south of 63780
  • 3-star Highway property
  • 64 sleeping rooms in hotel
From$85
Average 3.0 /5 Read Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston
+1-888-311-4278
220 South Interstate Dr., Sikeston, MO 63801 +1-888-311-4278 ~19.24 miles south of 63780
  • Cheap hotel
  • Gym / Fitness Center Available
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Sikeston/Miner Area - Sikeston
+1-888-469-4795
2609 East Malone, Sikeston, MO 63801 +1-888-469-4795 ~19.30 miles south of 63780
  • Low-priced Convention Center hotel
  • Complimentary breakfast is offered
From$60
Average 3.0 /5 Reviews Call BookMore Details
Drury Inn & Suites Jackson Missouri in Jackson
+1-888-734-9421
225 Drury Lane, Jackson, MO 63755 +1-888-734-9421 ~20.25 miles northwest of 63780
  • Affordable Suburban property
  • Access to gym on-site
From$79
Very Good 4.5 /5 Reviews Call BookMore Details
Hampton Inn Sikeston : 1240 Commerce Dr.
+1-888-841-5292
1240 Commerce Dr., Sikeston, MO 63801 +1-888-841-5292 ~21.91 miles south of 63780
  • Three Star Rural property
  • 4 floors in property
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel - Sikeston
+1-888-455-5160
115 Hospitality Dr., Sikeston, MO 63801 +1-888-455-5160 ~21.92 miles south of 63780
  • 3 star Rural hotel
  • Complimentary breakfast is offered
From$94
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hotel 7 Inn Anna
+1-888-965-8297
100 Richview Dr., Anna, IL 62906 +1-888-965-8297 ~25.02 miles northeast of 63780
  • Two-star hotel
From$60
Very Good 4.0 /5 Read Reviews Call BookMore Details
Econo Lodge Dexter
+1-888-906-6358
913 Outer Rd., Dexter, MO 63841 +1-888-906-6358 ~36.64 miles southwest of 63780
  • Low Cost hotel
  • 38 rooms in property
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Travelodge by Wyndham Dexter in Dexter
+1-888-749-6785
1608 West Business U.s. 60, Dexter, MO 63841 +1-888-749-6785 ~37.34 miles southwest of 63780
  • Midscale hotel
From$67
Very Good 4.0 /5 Read Reviews Call BookMore Details
Train Inn : 406 East Stoker St.
+1-888-878-9982
406 East Stoker St., Carbondale, IL 62901 +1-888-878-9982 ~41.10 miles north of 63780
  • Three Star Suburban property
  • Hotel has a green policy See policy
From$50
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino : 100 East Front St.
+1-888-389-4485
100 East Front St., Metropolis, IL 62960 +1-888-389-4485 ~41.18 miles east of 63780
  • High-end hotel
  • Check in time: 16:00
From$160
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Metropolis in Metropolis
+1-888-389-4121
203 East Front St., Metropolis, IL 62960 +1-888-389-4121 ~41.23 miles east of 63780
  • Cheap Riverfront hotel
  • 117 rooms in hotel
From$45
Average 3.0 /5 Hotel Reviews Call BookMore Details
Home2 Suites by Hilton Carbondale
+1-888-675-2083
200 West Elm St., Carbondale, IL 62901 +1-888-675-2083 ~41.29 miles north of 63780
  • 3-star Downtown property
  • 99 suites in property
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
University Inn of Carbondale in Carbondale
+1-800-716-8490
2400 West Main St., Carbondale, IL 62901 +1-800-716-8490 ~41.35 miles north of 63780
  • Affordable property
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Carbondale Value Inn & Suites : 700 East Main St.
+1-800-805-5223
700 East Main St., Carbondale, IL 62901 +1-800-805-5223 ~41.77 miles north of 63780
  • Two star Downtown hotel
  • 2 floors in hotel
From$54
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Carbondale
+1-888-965-1860
1180 East Main St., Carbondale, IL 62901 +1-888-965-1860 ~42.08 miles north of 63780
  • Low Cost hotel
  • 63 rooms in property
From$58
Average 3.0 /5 Hotel Reviews Call BookMore Details
Econo Lodge
+1-888-788-5576
1415 East 5th St., Metropolis, IL 62960 +1-888-788-5576 ~42.28 miles east of 63780
  • 2 star hotel
  • Check in time: 11:00
From$60
Not Good 1.0 /5 Review Score Call BookMore Details
Pear Tree Inn Paducah
+1-888-897-9207
5006 Hinkleville Rd., Paducah, KY 42001 +1-888-897-9207 ~42.53 miles east of 63780
  • Two-star Suburban property
  • Has environment-friendly policy Learn more
From$55
Very Good 4.0 /5 Review Score Call BookMore Details
Best Western Saluki Inn : 801 North Giant City Rd.
+1-888-311-4278
801 North Giant City Rd., Carbondale, IL 62902 +1-888-311-4278 ~42.55 miles north of 63780
  • Midscale Downtown hotel
  • Check in time: 3:00pm
From$79
Average 3.0 /5 Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale - Murphysboro
+1-888-469-4795
128 East Walnut St., Murphysboro, IL 62966 +1-888-469-4795 ~42.58 miles north of 63780
  • Low priced property
  • Check in time: 14:00
Quality Inn Carbondale University Area
+1-888-734-9421
1415 East Main St., Carbondale, IL 62901 +1-888-734-9421 ~42.65 miles north of 63780
  • Midscale Suburban hotel
  • 2 floors in property
Residence Inn by Marriott Paducah in Paducah
+1-888-841-5292
3900 Coleman Crossing Circle, Paducah, KY 42001 +1-888-841-5292 ~43.20 miles east of 63780
  • Mid-scale Suburban property
  • 74 sleeping rooms in hotel
From$89
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Carbondale : 2175 Reed Station Pkwy.
+1-888-455-5160
2175 Reed Station Pkwy., Carbondale, IL 62901 +1-888-455-5160 ~43.48 miles northeast of 63780
  • 3 star Rural hotel
  • 2 conference rooms in property
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Metropolis : 2055 East 5th St.
+1-888-965-8297
2055 East 5th St., Metropolis, IL 62960 +1-888-965-8297 ~43.53 miles east of 63780
  • Economy Highway hotel
  • Free breakfast
From$60
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites Metropolis I-24 in Metropolis
+1-888-906-6358
2118 East 5th St., Metropolis, IL 62960 +1-888-906-6358 ~43.57 miles east of 63780
  • Affordable hotel
  • 52 sleeping rooms in hotel
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Carbondale-Conference Center, an IHG Hotel in Carbondale
+1-888-749-6785
2300 Reed Station Pkwy., Carbondale, IL 62901 +1-888-749-6785 ~43.63 miles northeast of 63780
  • Affordable Rural hotel
  • Gym / Fitness Center Available
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Perryville
+1-888-878-9982
1119 Vincent Dr., Perryville, MO 63775 +1-888-878-9982 ~43.66 miles northwest of 63780
  • Low priced Highway hotel
  • 64 rooms in hotel
From$59
Very Good 4.0 /5 Latest Reviews Call BookMore Details
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