63780 Hotels/Accommodations

Candlewood Suites Cape Girardeau by IHG - Cape Girardeau
+1-888-389-4121
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 +1-888-389-4121 ~9.94 miles northwest of 63780
  • Two star Highway hotel
  • Check-in time: 3:00PM
From$69
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown in Cape Girardeau
+1-888-675-2083
400 Broadway St., Cape Girardeau, MO 63701 +1-888-675-2083 ~10.03 miles north of 63780
  • Mid-scale Downtown property
  • Check in: 3:00 pm
From$80
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East - Cape Girardeau
+1-800-716-8490
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 +1-800-716-8490 ~10.65 miles northwest of 63780
  • Midscale Highway hotel
  • 86 rooms in hotel
From$80
Excellent 5.0 /5 Review Score Call BookMore Details
Victorian Inn & Suites - Cape Girardeau
+1-800-805-5223
3256 William St., Cape Girardeau, MO 63703 +1-800-805-5223 ~10.72 miles northwest of 63780
  • 3-star Golf Course hotel
  • 133 sleeping rooms in hotel
From$79
Average 3.0 /5 Review Score Call BookMore Details
Auburn Place Hotel & Suites : 3265 Williams St.
+1-888-965-1860
3265 Williams St., Cape Girardeau, MO 63702 +1-888-965-1860 ~10.73 miles northwest of 63780
  • 3-star Highway property
  • 5 suites in hotel
From$58
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 by Ihg
+1-888-788-5576
3253 William St., Cape Girardeau, MO 63701 +1-888-788-5576 ~10.75 miles northwest of 63780
  • Affordable hotel
  • Gym / Fitness Center Available
From$80
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites Cape Girardeau - Cape Girardeay
+1-888-897-9207
433 Cape West Crossing, Cape Girardeay, MO 63703 +1-888-897-9207 ~10.79 miles northwest of 63780
  • 3 star property
  • Complimentary breakfast is offered
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center
+1-888-311-4278
3248 William St., Cape Girardeau, MO 63701 +1-888-311-4278 ~10.82 miles northwest of 63780
  • Inexpensive Highway hotel
  • 3 floors in hotel
From$66
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West : 103 Cape West Pkwy.
+1-888-469-4795
103 Cape West Pkwy., Cape Girardeau, MO 63701 +1-888-469-4795 ~10.83 miles northwest of 63780
  • Economy property
  • 81 rooms in hotel
From$59
Average 3.0 /5 Latest Reviews Call BookMore Details
Drury Suites Cape Girardeau
+1-888-734-9421
3303 Campster Dr., Cape Girardeau, MO 63701 +1-888-734-9421 ~10.94 miles northwest of 63780
  • Affordable Highway property
  • Check-in: 3:00 PM
From$85
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Drury Lodge : 104 South Vantage Dr.
+1-888-841-5292
104 South Vantage Dr., Cape Girardeau, MO 63701 +1-888-841-5292 ~11.10 miles northwest of 63780
  • Mid-scale Highway property
  • Gym / Fitness Center Available
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn - Cape Girardeau
+1-888-455-5160
2011 North Kingshighway St., Cape Girardeau, MO 63701 +1-888-455-5160 ~13.04 miles northwest of 63780
  • Cheap hotel
  • 2 floors in property
From$60
Very Good 4.0 /5 Recent Reviews Call BookMore Details
TRU by Hilton Cape Girardeau - Cape Girardeau
+1-888-965-8297
2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 +1-888-965-8297 ~14.23 miles northwest of 63780
  • Three Star Highway hotel
  • 90 sleeping rooms in hotel
From$80
Average 3.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau in Jackson
+1-888-906-6358
3003 South Old Orchard Rd., Jackson, MO 63755 +1-888-906-6358 ~14.79 miles northwest of 63780
  • 3 star Highway hotel
  • Gym / Fitness Center Available
From$85
Very Good 4.0 /5 Review Score Call BookMore Details
Comfort Suites
+1-888-749-6785
2904 Old Orchard Rd., Jackson, MO 63755 +1-888-749-6785 ~14.89 miles northwest of 63780
  • Affordable Highway hotel
  • Hotel has a green policy See more
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn Cairo I-57
+1-888-878-9982
13201 Kessler Rd., Cairo, IL 62914 +1-888-878-9982 ~17.84 miles east of 63780
  • Mid-scale Highway property
  • Check in: 3 pm
Super 8 by Wyndham Charleston/Sikeston East MO in Charleston
+1-888-389-4485
310 South Story, Charleston, MO 63834 +1-888-389-4485 ~18.99 miles southeast of 63780
  • Low-priced Highway hotel
  • 7 suites in hotel
From$42
Average 3.5 /5 Read Reviews Call BookMore Details
Motel 6 Sikeston Mo : 110 South Interstate Dr.
+1-888-389-4121
110 South Interstate Dr., SIKESTON, MO 63801 +1-888-389-4121 ~19.00 miles south of 63780
  • Economy hotel
From$60
Average 3.0 /5 Review Score Call BookMore Details
Best Western Plus Sikeston
+1-888-675-2083
120 South Interstate Dr., Sikeston, MO 63801 +1-888-675-2083 ~19.04 miles south of 63780
  • Two-star Highway hotel
  • Free breakfast available
From$43
Very Good 4.0 /5 Reviews Call BookMore Details
Quality Inn Charleston - Sikeston - Charleston
+1-800-716-8490
102 Drake St., Charleston, MO 63834 +1-800-716-8490 ~19.06 miles south of 63780
  • Two-star Highway hotel
  • Fitness / Gym is on-site
From$59
Average 3.0 /5 Review Score Call BookMore Details
Americas Best Value Inn Ullin Mounds
+1-800-805-5223
128 Cheekwood Lane, Ullin, IL 62992 +1-800-805-5223 ~19.13 miles east of 63780
  • Two star property
  • Comp. Breakfast
From$60
Average 3.0 /5 Review Score Call BookMore Details
Pear Tree Inn Sikeston - Sikeston
+1-888-965-1860
2602 East Malone, Sikeston, MO 63801 +1-888-965-1860 ~19.13 miles south of 63780
  • 3 star Suburban property
  • 2 suites in property
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) in Sikeston
+1-888-788-5576
100 Matthews Lane, Sikeston, MO 63801 +1-888-788-5576 ~19.17 miles south of 63780
  • 3 star Highway hotel
  • Free breakfast available
From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Comfort Inn : 109 Matthews Lane
+1-888-897-9207
109 Matthews Lane, Sikeston, MO 63801 +1-888-897-9207 ~19.18 miles south of 63780
  • Affordable Highway property
  • Hotel has 64 rooms
From$85
Average 3.0 /5 Latest Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston : 220 South Interstate Dr.
+1-888-311-4278
220 South Interstate Dr., Sikeston, MO 63801 +1-888-311-4278 ~19.21 miles south of 63780
  • Low Cost hotel
  • Access to gym on-site
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Sikeston/Miner Area
+1-888-469-4795
2609 East Malone, Sikeston, MO 63801 +1-888-469-4795 ~19.27 miles south of 63780
  • Low Cost Convention Center hotel
  • Check-in: 01:00
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn Sikeston
+1-888-734-9421
1240 Commerce Dr., Sikeston, MO 63801 +1-888-734-9421 ~21.87 miles south of 63780
  • 3-star Rural property
  • Hotel has 8 suites
From$80
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel - Sikeston
+1-888-841-5292
115 Hospitality Dr., Sikeston, MO 63801 +1-888-841-5292 ~21.89 miles south of 63780
  • 3-star Rural property
  • 73 rooms in hotel
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Hotel 7 Inn Anna
+1-888-455-5160
100 Richview Dr., Anna, IL 62906 +1-888-455-5160 ~25.00 miles northeast of 63780
  • Economy hotel
From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Econo Lodge Dexter in Dexter
+1-888-965-8297
913 Outer Rd., Dexter, MO 63841 +1-888-965-8297 ~36.54 miles southwest of 63780
  • Economical property
  • 38 rooms in hotel
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Travelodge by Wyndham Dexter : 1608 West Business U.s. 60
+1-888-906-6358
1608 West Business U.s. 60, Dexter, MO 63841 +1-888-906-6358 ~37.23 miles southwest of 63780
  • Mid-scale hotel
From$67
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Train Inn : 406 East Stoker St.
+1-888-749-6785
406 East Stoker St., Carbondale, IL 62901 +1-888-749-6785 ~41.06 miles north of 63780
  • Mid-scale Suburban hotel
  • 7 rooms in property
From$50
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destinatio
+1-888-878-9982
100 East Front St., Metropolis, IL 62960 +1-888-878-9982 ~41.12 miles east of 63780
  • Expensive property
  • 12 suites in hotel
From$160
Very Good 4.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Metropolis
+1-888-389-4485
203 East Front St., Metropolis, IL 62960 +1-888-389-4485 ~41.16 miles east of 63780
  • Cheap Riverfront property
  • 117 rooms in property
From$45
Average 3.0 /5 Reviews Call BookMore Details
Home2 Suites by Hilton Carbondale
+1-888-389-4121
200 West Elm St., Carbondale, IL 62901 +1-888-389-4121 ~41.25 miles north of 63780
  • Three Star Downtown property
  • Hotel has 99 rooms
From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
University Inn of Carbondale - Carbondale
+1-888-675-2083
2400 West Main St., Carbondale, IL 62901 +1-888-675-2083 ~41.31 miles north of 63780
  • Three Star property
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Carbondale Value Inn & Suites in Carbondale
+1-800-716-8490
700 East Main St., Carbondale, IL 62901 +1-800-716-8490 ~41.73 miles north of 63780
  • Two star Downtown hotel
  • Check in: 3:00pm
From$54
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Carbondale
+1-800-805-5223
1180 East Main St., Carbondale, IL 62901 +1-800-805-5223 ~42.04 miles north of 63780
  • Two-star hotel
  • Check in: 02:00 pm
From$58
Average 3.0 /5 Guest Reviews Call BookMore Details
Econo Lodge in Metropolis
+1-888-965-1860
1415 East 5th St., Metropolis, IL 62960 +1-888-965-1860 ~42.21 miles east of 63780
  • Low-priced hotel
  • 45 rooms in hotel
From$60
Not Good 1.0 /5 Latest Reviews Call BookMore Details
Pear Tree Inn Paducah
+1-888-788-5576
5006 Hinkleville Rd., Paducah, KY 42001 +1-888-788-5576 ~42.44 miles east of 63780
  • Two-star Suburban property
  • Hotel has a green policy Learn more
From$55
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Best Western Saluki Inn - Carbondale
+1-888-897-9207
801 North Giant City Rd., Carbondale, IL 62902 +1-888-897-9207 ~42.52 miles north of 63780
  • Mid-scale Downtown hotel
  • Check-in: 3:00pm
From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale in Murphysboro
+1-888-311-4278
128 East Walnut St., Murphysboro, IL 62966 +1-888-311-4278 ~42.53 miles north of 63780
  • Two star hotel
  • Check-in: 14:00
Quality Inn Carbondale University Area : 1415 East Main St.
+1-888-469-4795
1415 East Main St., Carbondale, IL 62901 +1-888-469-4795 ~42.61 miles north of 63780
  • Affordable Suburban property
  • Comp. Breakfast
Residence Inn by Marriott Paducah
+1-888-734-9421
3900 Coleman Crossing Circle, Paducah, KY 42001 +1-888-734-9421 ~43.10 miles east of 63780
  • 3 star Suburban hotel
  • Hotel has 3 floors
From$89
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Carbondale
+1-888-841-5292
2175 Reed Station Pkwy., Carbondale, IL 62901 +1-888-841-5292 ~43.44 miles northeast of 63780
  • Affordable Rural hotel
  • Fitness center on property
From$80
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Metropolis in Metropolis
+1-888-455-5160
2055 East 5th St., Metropolis, IL 62960 +1-888-455-5160 ~43.47 miles east of 63780
  • 2 star Highway hotel
  • Check-in time: 02:00PM
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites Metropolis I-24 in Metropolis
+1-888-965-8297
2118 East 5th St., Metropolis, IL 62960 +1-888-965-8297 ~43.50 miles east of 63780
  • Three Star property
  • 52 rooms in property
From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Carbondale Conference Center An Ihg Hotel : 2300 Reed Station Pkwy.
+1-888-906-6358
2300 Reed Station Pkwy., Carbondale, IL 62901 +1-888-906-6358 ~43.59 miles northeast of 63780
  • Midscale Rural property
  • Hotel has 100 rooms
From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Metropolis Il : 2119 East 5th St.
+1-888-749-6785
2119 East 5th St., Metropolis, IL 62960 +1-888-749-6785 ~43.62 miles east of 63780
  • Cheap property
From$60
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Perryville
+1-888-878-9982
1119 Vincent Dr., Perryville, MO 63775 +1-888-878-9982 ~43.64 miles northwest of 63780
  • Economy Highway hotel
  • Check-in: 3:00pm
From$59
Very Good 4.0 /5 Reviews Call BookMore Details
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