63780 Hotels/Accommodations

Candlewood Suites Cape Girardeau by IHG in Cape Girardeau
+1-888-389-4121
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 +1-888-389-4121 ~9.94 miles northwest of 63780
  • Low-priced Highway hotel
  • 85 suites in property
From$69
Very good 4.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown
+1-888-675-2083
400 Broadway St., Cape Girardeau, MO 63701 +1-888-675-2083 ~10.03 miles north of 63780
  • Midscale Downtown hotel
  • 78 rooms in hotel
From$80
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East in Cape Girardeau
+1-800-716-8490
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 +1-800-716-8490 ~10.65 miles northwest of 63780
  • Mid-scale Highway hotel
  • Check-in time: 15:00
From$80
Excellent 5.0 /5 Hotel Reviews Call BookMore Details
Victorian Inn & Suites
+1-800-805-5223
3256 William St., Cape Girardeau, MO 63703 +1-800-805-5223 ~10.72 miles northwest of 63780
  • 3 star Golf Course property
  • 133 rooms in hotel
From$79
Average 3.0 /5 Hotel Reviews Call BookMore Details
Auburn Place Hotel & Suites
+1-888-965-1860
3265 Williams St., Cape Girardeau, MO 63702 +1-888-965-1860 ~10.73 miles northwest of 63780
  • 3 star Highway hotel
  • 2 floors in property
From$58
Very good 4.5 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 by Ihg : 3253 William St.
+1-888-788-5576
3253 William St., Cape Girardeau, MO 63701 +1-888-788-5576 ~10.75 miles northwest of 63780
  • 3 star hotel
  • Fitness / Gym is on-site
From$80
Very good 4.5 /5 Reviews Call BookMore Details
Fairfield Inn & Suites Cape Girardeau - Cape Girardeay
+1-888-897-9207
433 Cape West Crossing, Cape Girardeay, MO 63703 +1-888-897-9207 ~10.79 miles northwest of 63780
  • Affordable property
  • 4 floors in property
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center : 3248 William St.
+1-888-311-4278
3248 William St., Cape Girardeau, MO 63701 +1-888-311-4278 ~10.82 miles northwest of 63780
  • Two star Highway hotel
  • Check-in: 3:00 pm
From$66
Very good 4.0 /5 Review Score Call BookMore Details
Pear Tree Inn Cape Girardeau West - Cape Girardeau
+1-888-469-4795
103 Cape West Pkwy., Cape Girardeau, MO 63701 +1-888-469-4795 ~10.83 miles northwest of 63780
  • 2 star property
  • Free breakfast available
From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
Drury Suites Cape Girardeau - Cape Girardeau
+1-888-734-9421
3303 Campster Dr., Cape Girardeau, MO 63701 +1-888-734-9421 ~10.94 miles northwest of 63780
  • 3-star Highway hotel
  • Hotel has a green policy See policy
From$85
Very good 4.5 /5 Recent Reviews Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau
+1-888-841-5292
3351 Percy Dr., Cape Girardeau, MO 63701 +1-888-841-5292 ~11.09 miles northwest of 63780
  • 3 star hotel
  • 8 floors in hotel
From$59
Average 3.0 /5 Latest Reviews Call BookMore Details
Drury Lodge
+1-888-455-5160
104 South Vantage Dr., Cape Girardeau, MO 63701 +1-888-455-5160 ~11.10 miles northwest of 63780
  • Mid-scale Highway property
  • Free breakfast
From$80
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn
+1-888-965-8297
2011 North Kingshighway St., Cape Girardeau, MO 63701 +1-888-965-8297 ~13.04 miles northwest of 63780
  • Low priced hotel
  • 2 floors in hotel
From$60
Very good 4.0 /5 Read Reviews Call BookMore Details
TRU by Hilton Cape Girardeau : 2520 Veterans Memorial Dr.
+1-888-906-6358
2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 +1-888-906-6358 ~14.23 miles northwest of 63780
  • Three Star Highway property
  • Check in: 3:00 pm
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau - Jackson
+1-888-749-6785
3003 South Old Orchard Rd., Jackson, MO 63755 +1-888-749-6785 ~14.79 miles northwest of 63780
  • 3 star Highway hotel
  • Hotel has 80 rooms
From$85
Very good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Suites - Jackson
+1-888-878-9982
2904 Old Orchard Rd., Jackson, MO 63755 +1-888-878-9982 ~14.89 miles northwest of 63780
  • Midscale Highway property
  • 3 floors in property
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn Cairo I-57
+1-888-389-4485
13201 Kessler Rd., Cairo, IL 62914 +1-888-389-4485 ~17.84 miles east of 63780
  • Three Star Highway hotel
  • Check in time: 3 pm
Super 8 by Wyndham Charleston/Sikeston East MO
+1-888-389-4121
310 South Story, Charleston, MO 63834 +1-888-389-4121 ~18.99 miles southeast of 63780
  • Economical Highway hotel
  • Check in time: 3:00pm
From$42
Average 3.5 /5 Hotel Reviews Call BookMore Details
Motel 6 Sikeston Mo - SIKESTON
+1-888-675-2083
110 South Interstate Dr., SIKESTON, MO 63801 +1-888-675-2083 ~19.00 miles south of 63780
  • 2-star property
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Best Western Plus Sikeston : 120 South Interstate Dr.
+1-800-716-8490
120 South Interstate Dr., Sikeston, MO 63801 +1-800-716-8490 ~19.04 miles south of 63780
  • Low Cost Highway hotel
  • Free breakfast available
From$43
Very good 4.0 /5 Reviews Call BookMore Details
Quality Inn Charleston - Sikeston in Charleston
+1-800-805-5223
102 Drake St., Charleston, MO 63834 +1-800-805-5223 ~19.06 miles south of 63780
  • 2-star Highway property
  • Gym is available on property
From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
Drury Inn & Suites Sikeston : 2608 East Malone Ave.
+1-888-965-1860
2608 East Malone Ave., Sikeston, MO 63801 +1-888-965-1860 ~19.13 miles south of 63780
  • 3 star Highway hotel
  • Check in time: 3:00 PM
From$104
Very good 4.5 /5 Review Score Call BookMore Details
Pear Tree Inn Sikeston in Sikeston
+1-888-788-5576
2602 East Malone, Sikeston, MO 63801 +1-888-788-5576 ~19.13 miles south of 63780
  • Mid-scale Suburban hotel
  • Has environment-friendly policy Read more
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds - Ullin
+1-888-897-9207
128 Cheekwood Lane, Ullin, IL 62992 +1-888-897-9207 ~19.13 miles east of 63780
  • 2-star property
  • 2 floors in property
From$60
Average 3.0 /5 Review Score Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) - Sikeston
+1-888-311-4278
100 Matthews Lane, Sikeston, MO 63801 +1-888-311-4278 ~19.17 miles south of 63780
  • Three Star Highway hotel
  • Hotel has 40 rooms
From$80
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Inn
+1-888-469-4795
109 Matthews Lane, Sikeston, MO 63801 +1-888-469-4795 ~19.18 miles south of 63780
  • 3-star Highway property
  • 64 rooms in property
From$85
Average 3.0 /5 Recent Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston
+1-888-734-9421
220 South Interstate Dr., Sikeston, MO 63801 +1-888-734-9421 ~19.21 miles south of 63780
  • Two-star property
  • Access to gym on-site
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Sikeston/Miner Area : 2609 East Malone
+1-888-841-5292
2609 East Malone, Sikeston, MO 63801 +1-888-841-5292 ~19.27 miles south of 63780
  • 2-star Convention Center property
  • Comp. Breakfast
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Drury Inn & Suites Jackson Missouri in Jackson
+1-888-455-5160
225 Drury Lane, Jackson, MO 63755 +1-888-455-5160 ~20.22 miles northwest of 63780
  • 3 star Suburban hotel
  • 4 floors in property
From$79
Very good 4.5 /5 Review Score Call BookMore Details
Hampton Inn Sikeston
+1-888-965-8297
1240 Commerce Dr., Sikeston, MO 63801 +1-888-965-8297 ~21.87 miles south of 63780
  • Midscale Rural property
  • Hotel has 4 floors
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel in Sikeston
+1-888-906-6358
115 Hospitality Dr., Sikeston, MO 63801 +1-888-906-6358 ~21.89 miles south of 63780
  • Affordable Rural property
  • 3 floors in property
From$80
Average 3.0 /5 Review Score Call BookMore Details
Hotel 7 Inn Anna - Anna
+1-888-749-6785
100 Richview Dr., Anna, IL 62906 +1-888-749-6785 ~25.00 miles northeast of 63780
  • Cheap hotel
From$60
Very good 4.0 /5 Guest Reviews Call BookMore Details
Econo Lodge Dexter
+1-888-878-9982
913 Outer Rd., Dexter, MO 63841 +1-888-878-9982 ~36.54 miles southwest of 63780
  • Economy property
  • 38 sleeping rooms in hotel
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Travelodge by Wyndham Dexter in Dexter
+1-888-389-4485
1608 West Business U.s. 60, Dexter, MO 63841 +1-888-389-4485 ~37.23 miles southwest of 63780
  • Mid-scale hotel
From$67
Very good 4.0 /5 Read Reviews Call BookMore Details
Train Inn : 406 East Stoker St.
+1-888-389-4121
406 East Stoker St., Carbondale, IL 62901 +1-888-389-4121 ~41.06 miles north of 63780
  • 3-star Suburban property
  • Hotel has an eco-friendly policy Learn more
From$50
Very good 4.0 /5 Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino
+1-888-675-2083
100 East Front St., Metropolis, IL 62960 +1-888-675-2083 ~41.12 miles east of 63780
  • Four-star property
  • Check in time: 16:00
From$160
Very good 4.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Metropolis : 203 East Front St.
+1-800-716-8490
203 East Front St., Metropolis, IL 62960 +1-800-716-8490 ~41.16 miles east of 63780
  • Economical Riverfront property
  • Hotel has 8 suites
From$45
Average 3.0 /5 Guest Reviews Call BookMore Details
Home2 Suites by Hilton Carbondale - Carbondale
+1-800-805-5223
200 West Elm St., Carbondale, IL 62901 +1-800-805-5223 ~41.25 miles north of 63780
  • Affordable Downtown property
  • Check in: 3:00 pm
From$99
Very good 4.0 /5 Review Score Call BookMore Details
University Inn of Carbondale : 2400 West Main St.
+1-888-965-1860
2400 West Main St., Carbondale, IL 62901 +1-888-965-1860 ~41.31 miles north of 63780
  • 3-star property
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Carbondale Value Inn & Suites in Carbondale
+1-888-788-5576
700 East Main St., Carbondale, IL 62901 +1-888-788-5576 ~41.73 miles north of 63780
  • 2 star Downtown hotel
  • 2 floors in hotel
From$54
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Carbondale : 1180 East Main St.
+1-888-897-9207
1180 East Main St., Carbondale, IL 62901 +1-888-897-9207 ~42.04 miles north of 63780
  • Economy property
  • 3 floors in property
From$58
Average 3.0 /5 Latest Reviews Call BookMore Details
Econo Lodge
+1-888-311-4278
1415 East 5th St., Metropolis, IL 62960 +1-888-311-4278 ~42.21 miles east of 63780
  • 2-star property
  • 45 sleeping rooms in hotel
From$60
Terrible 1.0 /5 Reviews Call BookMore Details
Pear Tree Inn Paducah in Paducah
+1-888-469-4795
5006 Hinkleville Rd., Paducah, KY 42001 +1-888-469-4795 ~42.44 miles east of 63780
  • Economical Suburban hotel
  • 2 floors in hotel
From$55
Very good 4.0 /5 Latest Reviews Call BookMore Details
Best Western Saluki Inn : 801 North Giant City Rd.
+1-888-734-9421
801 North Giant City Rd., Carbondale, IL 62902 +1-888-734-9421 ~42.52 miles north of 63780
  • Affordable Downtown hotel
  • Complimentary breakfast is offered
From$79
Average 3.0 /5 Read Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale - Murphysboro
+1-888-841-5292
128 East Walnut St., Murphysboro, IL 62966 +1-888-841-5292 ~42.53 miles north of 63780
  • Cheap hotel
  • 39 rooms in hotel
Quality Inn Carbondale University Area
+1-888-455-5160
1415 East Main St., Carbondale, IL 62901 +1-888-455-5160 ~42.61 miles north of 63780
  • 3-star Suburban property
  • 2 floors in hotel
From$30
Poor 2.0 /5 Reviews Call BookMore Details
Residence Inn by Marriott Paducah : 3900 Coleman Crossing Circle
+1-888-965-8297
3900 Coleman Crossing Circle, Paducah, KY 42001 +1-888-965-8297 ~43.10 miles east of 63780
  • Mid-scale Suburban property
  • 3 floors in hotel
From$89
Very good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Carbondale in Carbondale
+1-888-906-6358
2175 Reed Station Pkwy., Carbondale, IL 62901 +1-888-906-6358 ~43.44 miles northeast of 63780
  • 3 star Rural hotel
  • 80 rooms in hotel
From$80
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Metropolis
+1-888-749-6785
2055 East 5th St., Metropolis, IL 62960 +1-888-749-6785 ~43.47 miles east of 63780
  • Two-star Highway property
  • 63 rooms in property
From$60
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites Metropolis I-24 : 2118 East 5th St.
+1-888-878-9982
2118 East 5th St., Metropolis, IL 62960 +1-888-878-9982 ~43.50 miles east of 63780
  • Three Star hotel
  • 52 rooms in hotel
From$80
Very good 4.0 /5 Recent Reviews Call BookMore Details
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