63780 Hotels/Motels & Accommodations

Candlewood Suites Cape Girardeau by IHG : 485 South Mount Auburn Rd. 485 South Mount Auburn Rd., Cape Girardeau, MO 65703 Call ~9.94 miles northwest of 63780
  • Low priced Highway hotel
  • Gym is available on property
From$69
Very good 4.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown - Cape Girardeau 400 Broadway St., Cape Girardeau, MO 63701 Call ~10.03 miles north of 63780
  • Mid-scale Downtown hotel
  • Fitness / Gym is on-site
From$80
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East in Cape Girardeau 207 South Mount Auburn Rd., Cape Girardeau, MO 63703 Call ~10.65 miles northwest of 63780
  • 3-star Highway property
  • Free complimentary breakfast
From$80
Excellent 5.0 /5 Read Reviews Call BookMore Details
Victorian Inn & Suites : 3256 William St. 3256 William St., Cape Girardeau, MO 63703 Call ~10.72 miles northwest of 63780
  • Affordable Golf Course property
  • 5 suites in property
From$79
Average 3.0 /5 Reviews Call BookMore Details
Auburn Place Hotel & Suites - Cape Girardeau 3265 Williams St., Cape Girardeau, MO 63702 Call ~10.73 miles northwest of 63780
  • Affordable Highway property
  • Hotel has 2 floors
From$58
Very good 4.5 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 by Ihg in Cape Girardeau 3253 William St., Cape Girardeau, MO 63701 Call ~10.75 miles northwest of 63780
  • 3-star hotel
  • 2 meeting rooms in property
From$80
Very good 4.5 /5 Reviews Call BookMore Details
Fairfield Inn & Suites Cape Girardeau 433 Cape West Crossing, Cape Girardeay, MO 63703 Call ~10.79 miles northwest of 63780
  • 3 star property
  • Free breakfast
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center 3248 William St., Cape Girardeau, MO 63701 Call ~10.82 miles northwest of 63780
  • Economy Highway property
  • Has environment-friendly policy See more
From$66
Very good 4.0 /5 Latest Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West - Cape Girardeau 103 Cape West Pkwy., Cape Girardeau, MO 63701 Call ~10.83 miles northwest of 63780
  • Cheap hotel
  • 2 suites in property
From$9999999
Average 3.0 /5 Review Score Call BookMore Details
Drury Suites Cape Girardeau : 3303 Campster Dr. 3303 Campster Dr., Cape Girardeau, MO 63701 Call ~10.94 miles northwest of 63780
  • Affordable Highway property
  • Free breakfast available
From$85
Very good 4.5 /5 Guest Reviews Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau in Cape Girardeau 3351 Percy Dr., Cape Girardeau, MO 63701 Call ~11.09 miles northwest of 63780
  • 3-star property
  • Complimentary breakfast is offered
From$9999999
Average 3.0 /5 Recent Reviews Call BookMore Details
Drury Lodge - Cape Girardeau 104 South Vantage Dr., Cape Girardeau, MO 63701 Call ~11.10 miles northwest of 63780
  • Midscale Highway property
  • Fitness center on property
From$80
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn Cape Girardeau North : 2011 North Kingshighway St. 2011 North Kingshighway St., Cape Girardeau, MO 63701 Call ~13.04 miles northwest of 63780
  • Two star hotel
  • Hotel has an eco-friendly policy Read more
From$60
Very good 4.0 /5 Reviews Call BookMore Details
TRU by Hilton Cape Girardeau 2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 Call ~14.23 miles northwest of 63780
  • Three Star Highway property
  • Free breakfast
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau : 3003 South Old Orchard Rd. 3003 South Old Orchard Rd., Jackson, MO 63755 Call ~14.79 miles northwest of 63780
  • Midscale Highway property
  • 80 sleeping rooms in hotel
From$85
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Comfort Suites 2904 Old Orchard Rd., Jackson, MO 63755 Call ~14.89 miles northwest of 63780
  • Mid-scale Highway hotel
  • Has environment-friendly policy See policy
From$80
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn Cairo I-57 : 13201 Kessler Rd. 13201 Kessler Rd., Cairo, IL 62914 Call ~17.84 miles east of 63780
  • Three Star Highway property
  • Check in: 3 pm
From$60
Poor 2.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Charleston/Sikeston East MO in Charleston 310 South Story, Charleston, MO 63834 Call ~18.99 miles southeast of 63780
  • Low priced Highway property
  • 60 rooms in hotel
From$42
Average 3.5 /5 Recent Reviews Call BookMore Details
Motel 6 Sikeston Mo - SIKESTON 110 South Interstate Dr., SIKESTON, MO 63801 Call ~19.00 miles south of 63780
  • Economy property
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Best Western Plus Sikeston I-55 : 120 South Interstate Dr. 120 South Interstate Dr., Sikeston, MO 63801 Call ~19.04 miles south of 63780
  • Economy Highway property
  • Hotel has a green policy Learn more
From$43
Very good 4.0 /5 Guest Reviews Call BookMore Details
The Riverstone Hotel Charleston-Sikeston in Charleston 102 Drake St., Charleston, MO 63834 Call ~19.06 miles south of 63780
  • Cheap Highway hotel
  • Check-in time: 3:00PM
From$59
Average 3.0 /5 Reviews Call BookMore Details
Drury Inn & Suites Sikeston in Sikeston 2608 East Malone Ave., Sikeston, MO 63801 Call ~19.13 miles south of 63780
  • Mid-scale Highway property
  • Fitness + Health Center
From$104
Very good 4.5 /5 Read Reviews Call BookMore Details
Pear Tree Inn Sikeston : 2602 East Malone 2602 East Malone, Sikeston, MO 63801 Call ~19.13 miles south of 63780
  • Affordable Suburban hotel
  • Hotel has 4 floors
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds in Ullin 128 Cheekwood Lane, Ullin, IL 62992 Call ~19.13 miles east of 63780
  • Economical property
  • Check in time: 15:00
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) in Sikeston 100 Matthews Lane, Sikeston, MO 63801 Call ~19.17 miles south of 63780
  • 3-star Highway hotel
  • Free breakfast available
From$80
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Inn 109 Matthews Lane, Sikeston, MO 63801 Call ~19.18 miles south of 63780
  • 3 star Highway hotel
  • 64 sleeping rooms in hotel
From$85
Average 3.0 /5 Guest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Sikeston 220 South Interstate Dr., Sikeston, MO 63801 Call ~19.21 miles south of 63780
  • Low Cost property
  • Check-in time: 03:00 PM
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Sikeston/Miner Area - Sikeston 2609 East Malone, Sikeston, MO 63801 Call ~19.27 miles south of 63780
  • Low-priced Convention Center hotel
  • Check-in: 01:00
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Drury Inn & Suites Jackson Missouri in Jackson 225 Drury Lane, Jackson, MO 63755 Call ~20.22 miles northwest of 63780
  • Three Star Suburban property
  • Complimentary breakfast is offered
From$79
Very good 4.5 /5 Read Reviews Call BookMore Details
Hampton Inn Sikeston 1240 Commerce Dr., Sikeston, MO 63801 Call ~21.87 miles south of 63780
  • Mid-scale Rural hotel
  • Hotel has 92 rooms
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel - Sikeston 115 Hospitality Dr., Sikeston, MO 63801 Call ~21.89 miles south of 63780
  • Midscale Rural hotel
  • Check in time: 3:00pm
From$80
Average 3.0 /5 Review Score Call BookMore Details
Hotel 7 Inn Anna in Anna 100 Richview Dr., Anna, IL 62906 Call ~25.00 miles northeast of 63780
  • Cheap hotel
From$60
Very good 4.0 /5 Review Score Call BookMore Details
Econo Lodge Dexter : 913 Outer Rd. 913 Outer Rd., Dexter, MO 63841 Call ~36.54 miles southwest of 63780
  • Low Cost property
  • 38 rooms in property
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Travelodge by Wyndham Dexter in Dexter 1608 West Business U.s. 60, Dexter, MO 63841 Call ~37.23 miles southwest of 63780
  • Midscale Suburban property
  • Gym is available on property
From$67
Very good 4.0 /5 Recent Reviews Call BookMore Details
Train Inn in Carbondale 406 East Stoker St., Carbondale, IL 62901 Call ~41.06 miles north of 63780
  • 3-star Suburban property
  • 7 rooms in hotel
From$50
Very good 4.0 /5 Guest Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destinatio - Metropolis 100 East Front St., Metropolis, IL 62960 Call ~41.12 miles east of 63780
  • Four star property
  • Check in: 16:00
From$160
Very good 4.0 /5 Recent Reviews Call BookMore Details
Baymont by Wyndham Metropolis 203 East Front St., Metropolis, IL 62960 Call ~41.16 miles east of 63780
  • Economy Riverfront property
  • Check-in: 3:00PM
From$45
Average 3.0 /5 Guest Reviews Call BookMore Details
Home2 Suites by Hilton Carbondale : 200 West Elm St. 200 West Elm St., Carbondale, IL 62901 Call ~41.25 miles north of 63780
  • Three Star Downtown property
  • Gym is available on property
From$99
Very good 4.0 /5 Reviews Call BookMore Details
University Inn of Carbondale in Carbondale 2400 West Main St., Carbondale, IL 62901 Call ~41.31 miles north of 63780
  • Mid-scale property
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Carbondale Value Inn & Suites 700 East Main St., Carbondale, IL 62901 Call ~41.73 miles north of 63780
  • 2 star Downtown property
  • Check in: 3:00pm
From$54
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Carbondale 1180 East Main St., Carbondale, IL 62901 Call ~42.04 miles north of 63780
  • Two star hotel
  • 63 sleeping rooms in hotel
From$58
Average 3.0 /5 Review Score Call BookMore Details
Econo Lodge : 1415 East 5th St. 1415 East 5th St., Metropolis, IL 62960 Call ~42.21 miles east of 63780
  • Low-priced property
  • Check in time: 11:00
From$60
Terrible 1.0 /5 Reviews Call BookMore Details
Pear Tree Inn Paducah - Paducah 5006 Hinkleville Rd., Paducah, KY 42001 Call ~42.44 miles east of 63780
  • Cheap Suburban property
  • Access to gym on-site
From$55
Very good 4.0 /5 Recent Reviews Call BookMore Details
Best Western Saluki Inn 801 North Giant City Rd., Carbondale, IL 62902 Call ~42.52 miles north of 63780
  • Three Star Downtown property
  • Check in time: 3:00pm
From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale 128 East Walnut St., Murphysboro, IL 62966 Call ~42.53 miles north of 63780
  • Low priced hotel
  • Check in time: 14:00
Quality Inn Carbondale University Area 1415 East Main St., Carbondale, IL 62901 Call ~42.61 miles north of 63780
  • Three Star Suburban hotel
  • Hotel has 2 suites
Residence Inn by Marriott Paducah 3900 Coleman Crossing Circle, Paducah, KY 42001 Call ~43.10 miles east of 63780
  • Midscale Suburban hotel
  • 74 suites in property
From$89
Very good 4.0 /5 Reviews Call BookMore Details
Hampton Inn Carbondale in Carbondale 2175 Reed Station Pkwy., Carbondale, IL 62901 Call ~43.44 miles northeast of 63780
  • Mid-scale Rural hotel
  • Check-in time: 3:00pm
From$80
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Metropolis - Metropolis 2055 East 5th St., Metropolis, IL 62960 Call ~43.47 miles east of 63780
  • Two star Highway hotel
  • Check in time: 02:00PM
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Metropolis I-24 - Metropolis 2118 East 5th St., Metropolis, IL 62960 Call ~43.50 miles east of 63780
  • Three Star property
  • Check in: 11:00
From$80
Very good 4.0 /5 Recent Reviews Call BookMore Details
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