63780 Hotels/Accommodations

Candlewood Suites Cape Girardeau by IHG : 485 South Mount Auburn Rd.
+1-888-389-4121
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 +1-888-389-4121 ~9.95 miles northwest of 63780
  • Low priced Highway property
  • Has environment-friendly policy See more
From$69
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown in Cape Girardeau
+1-888-675-2083
400 Broadway St., Cape Girardeau, MO 63701 +1-888-675-2083 ~10.05 miles north of 63780
  • 3 star Downtown property
  • 78 rooms in property
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East
+1-800-716-8490
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 +1-800-716-8490 ~10.67 miles northwest of 63780
  • Three Star Highway hotel
  • 86 rooms in hotel
From$80
Excellent 5.0 /5 Guest Reviews Call BookMore Details
Victorian Inn & Suites
+1-800-805-5223
3256 William St., Cape Girardeau, MO 63703 +1-800-805-5223 ~10.74 miles northwest of 63780
  • 3-star Golf Course property
  • Free breakfast
From$79
Average 3.0 /5 Read Reviews Call BookMore Details
Auburn Place Hotel & Suites : 3265 Williams St.
+1-888-965-1860
3265 Williams St., Cape Girardeau, MO 63702 +1-888-965-1860 ~10.74 miles northwest of 63780
  • Three Star Highway hotel
  • Free comp. breakfast
From$58
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55
+1-888-788-5576
3253 William St., Cape Girardeau, MO 63701 +1-888-788-5576 ~10.77 miles northwest of 63780
  • 3-star hotel
  • Fitness center on property
From$80
Very Good 4.5 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites Cape Girardeau
+1-888-897-9207
433 Cape West Crossing, Cape Girardeay, MO 63703 +1-888-897-9207 ~10.80 miles northwest of 63780
  • Mid-scale hotel
  • 4 floors in property
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center - Cape Girardeau
+1-888-311-4278
3248 William St., Cape Girardeau, MO 63701 +1-888-311-4278 ~10.83 miles northwest of 63780
  • Inexpensive Highway property
  • Comp. Breakfast
From$66
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West - Cape Girardeau
+1-888-469-4795
103 Cape West Pkwy., Cape Girardeau, MO 63701 +1-888-469-4795 ~10.84 miles northwest of 63780
  • Economy hotel
  • 2 suites in property
From$59
Average 3.0 /5 Latest Reviews Call BookMore Details
Drury Suites Cape Girardeau
+1-888-734-9421
3303 Campster Dr., Cape Girardeau, MO 63701 +1-888-734-9421 ~10.95 miles northwest of 63780
  • Midscale Highway property
  • Hotel has 5 floors
From$85
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau
+1-888-841-5292
3351 Percy Dr., Cape Girardeau, MO 63701 +1-888-841-5292 ~11.10 miles northwest of 63780
  • 3 star property
  • Fitness center on property
From$59
Average 3.0 /5 Latest Reviews Call BookMore Details
Drury Lodge : 104 South Vantage Dr.
+1-888-455-5160
104 South Vantage Dr., Cape Girardeau, MO 63701 +1-888-455-5160 ~11.11 miles northwest of 63780
  • 3 star Highway hotel
  • Check in time: 3:00pm
From$80
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn
+1-888-965-8297
2011 North Kingshighway St., Cape Girardeau, MO 63701 +1-888-965-8297 ~13.06 miles northwest of 63780
  • Cheap property
  • Hotel has 2 floors
From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
TRU by Hilton Cape Girardeau
+1-888-906-6358
2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 +1-888-906-6358 ~14.25 miles northwest of 63780
  • Mid-scale Highway hotel
  • Check-in: 3:00 pm
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau in Jackson
+1-888-749-6785
3003 South Old Orchard Rd., Jackson, MO 63755 +1-888-749-6785 ~14.80 miles northwest of 63780
  • Affordable Highway hotel
  • Gym is available on property
From$85
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Suites Jackson-Cape Girardeau
+1-888-878-9982
2904 Old Orchard Rd., Jackson, MO 63755 +1-888-878-9982 ~14.91 miles northwest of 63780
  • Affordable Highway hotel
  • Comp. Breakfast
From$65
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Suites in Jackson
+1-888-389-4485
2904 Old Orchard Rd., Jackson, 63755 United States +1-888-389-4485 ~14.91 miles northwest of 63780
  • High-end Highway property
  • Hotel has 64 rooms
From$125
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn Cairo I-57 in Cairo
+1-888-389-4121
13201 Kessler Rd., Cairo, IL 62914 +1-888-389-4121 ~17.88 miles east of 63780
  • Midscale Highway property
  • Hotel has 2 floors
Super 8 by Wyndham Charleston/Sikeston East MO in Charleston
+1-888-675-2083
310 South Story, Charleston, MO 63834 +1-888-675-2083 ~19.03 miles southeast of 63780
  • 2 star Highway hotel
  • 60 rooms in property
From$42
Average 3.5 /5 Recent Reviews Call BookMore Details
Motel 6 Sikeston Mo : 110 South Interstate Dr.
+1-800-716-8490
110 South Interstate Dr., SIKESTON, MO 63801 +1-800-716-8490 ~19.03 miles south of 63780
  • Low-priced hotel
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Best Western Plus Sikeston in Sikeston
+1-800-805-5223
120 South Interstate Dr., Sikeston, MO 63801 +1-800-805-5223 ~19.07 miles south of 63780
  • Cheap Highway property
  • Hotel has an eco-friendly policy See more
From$43
Very Good 4.0 /5 Review Score Call BookMore Details
Quality Inn Charleston - Sikeston
+1-888-965-1860
102 Drake St., Charleston, MO 63834 +1-888-965-1860 ~19.09 miles south of 63780
  • Cheap Highway hotel
  • Fitness + Health Center
From$59
Average 3.0 /5 Guest Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds : 128 Cheekwood Lane
+1-888-788-5576
128 Cheekwood Lane, Ullin, IL 62992 +1-888-788-5576 ~19.15 miles east of 63780
  • 2-star hotel
  • 40 rooms in property
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Drury Inn & Suites Sikeston - Sikeston
+1-888-897-9207
2608 East Malone Ave., Sikeston, MO 63801 +1-888-897-9207 ~19.16 miles south of 63780
  • Midscale Highway hotel
  • Fitness / Gym is on-site
From$104
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Pear Tree Inn Sikeston : 2602 East Malone
+1-888-311-4278
2602 East Malone, Sikeston, MO 63801 +1-888-311-4278 ~19.16 miles south of 63780
  • Mid-scale Suburban property
  • Fitness / Gym is on-site
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
+1-888-469-4795
100 Matthews Lane, Sikeston, MO 63801 +1-888-469-4795 ~19.20 miles south of 63780
  • Three Star Highway hotel
  • Comp. Breakfast
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Inn : 109 Matthews Lane
+1-888-734-9421
109 Matthews Lane, Sikeston, MO 63801 +1-888-734-9421 ~19.21 miles south of 63780
  • Affordable Highway property
  • Check in time: 11:00
From$85
Average 3.0 /5 Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston in Sikeston
+1-888-841-5292
220 South Interstate Dr., Sikeston, MO 63801 +1-888-841-5292 ~19.24 miles south of 63780
  • Two star hotel
  • Check-in time: 03:00 PM
From$60
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Sikeston/Miner Area
+1-888-455-5160
2609 East Malone, Sikeston, MO 63801 +1-888-455-5160 ~19.30 miles south of 63780
  • Two star Convention Center hotel
  • Check in: 01:00
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Drury Inn & Suites Jackson Missouri : 225 Drury Lane
+1-888-965-8297
225 Drury Lane, Jackson, MO 63755 +1-888-965-8297 ~20.25 miles northwest of 63780
  • Three Star Suburban property
  • 24 suites in property
From$79
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Hampton Inn Sikeston in Sikeston
+1-888-906-6358
1240 Commerce Dr., Sikeston, MO 63801 +1-888-906-6358 ~21.91 miles south of 63780
  • 3 star Rural property
  • Free complimentary breakfast
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel - Sikeston
+1-888-749-6785
115 Hospitality Dr., Sikeston, MO 63801 +1-888-749-6785 ~21.92 miles south of 63780
  • Three Star Rural property
  • Check-in: 3:00pm
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Hotel 7 Inn Anna
+1-888-878-9982
100 Richview Dr., Anna, IL 62906 +1-888-878-9982 ~25.02 miles northeast of 63780
  • Cheap property
From$60
Very Good 4.0 /5 Read Reviews Call BookMore Details
Econo Lodge Dexter - Dexter
+1-888-389-4485
913 Outer Rd., Dexter, MO 63841 +1-888-389-4485 ~36.64 miles southwest of 63780
  • Two star hotel
  • Check-in time: 11:00
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Travelodge by Wyndham Dexter in Dexter
+1-888-389-4121
1608 West Business U.s. 60, Dexter, MO 63841 +1-888-389-4121 ~37.34 miles southwest of 63780
  • 3 star hotel
From$67
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Train Inn : 406 East Stoker St.
+1-888-675-2083
406 East Stoker St., Carbondale, IL 62901 +1-888-675-2083 ~41.10 miles north of 63780
  • 3 star Suburban property
  • Check-in time: 2pm
From$50
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino - Metropolis
+1-800-716-8490
100 East Front St., Metropolis, IL 62960 +1-800-716-8490 ~41.18 miles east of 63780
  • 4-star hotel
  • 7 floors in hotel
From$160
Very Good 4.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Metropolis : 203 East Front St.
+1-800-805-5223
203 East Front St., Metropolis, IL 62960 +1-800-805-5223 ~41.23 miles east of 63780
  • Two-star Riverfront property
  • Check in time: 3:00PM
From$45
Average 3.0 /5 Hotel Reviews Call BookMore Details
Home2 Suites by Hilton Carbondale - Carbondale
+1-888-965-1860
200 West Elm St., Carbondale, IL 62901 +1-888-965-1860 ~41.29 miles north of 63780
  • Three Star Downtown property
  • 99 suites in property
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
University Inn of Carbondale
+1-888-788-5576
2400 West Main St., Carbondale, IL 62901 +1-888-788-5576 ~41.35 miles north of 63780
  • 3-star property
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Carbondale Value Inn & Suites in Carbondale
+1-888-897-9207
700 East Main St., Carbondale, IL 62901 +1-888-897-9207 ~41.77 miles north of 63780
  • Two star Downtown hotel
  • 41 rooms in hotel
From$54
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Carbondale in Carbondale
+1-888-311-4278
1180 East Main St., Carbondale, IL 62901 +1-888-311-4278 ~42.08 miles north of 63780
  • Two star property
  • Check-in time: 02:00 pm
From$58
Average 3.0 /5 Recent Reviews Call BookMore Details
Econo Lodge
+1-888-469-4795
1415 East 5th St., Metropolis, IL 62960 +1-888-469-4795 ~42.28 miles east of 63780
  • Low-priced hotel
  • 45 rooms in property
From$60
Not Good 1.0 /5 Guest Reviews Call BookMore Details
Pear Tree Inn Paducah in Paducah
+1-888-734-9421
5006 Hinkleville Rd., Paducah, KY 42001 +1-888-734-9421 ~42.53 miles east of 63780
  • Two-star Suburban property
  • Free breakfast available
From$55
Very Good 4.0 /5 Review Score Call BookMore Details
Best Western Saluki Inn : 801 North Giant City Rd.
+1-888-841-5292
801 North Giant City Rd., Carbondale, IL 62902 +1-888-841-5292 ~42.55 miles north of 63780
  • Three Star Downtown hotel
  • 3 floors in hotel
From$79
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale in Murphysboro
+1-888-455-5160
128 East Walnut St., Murphysboro, IL 62966 +1-888-455-5160 ~42.58 miles north of 63780
  • Low-priced property
  • 39 rooms in hotel
Quality Inn Carbondale University Area
+1-888-965-8297
1415 East Main St., Carbondale, IL 62901 +1-888-965-8297 ~42.65 miles north of 63780
  • 3-star Suburban property
  • Complimentary breakfast is offered
Residence Inn by Marriott Paducah
+1-888-906-6358
3900 Coleman Crossing Circle, Paducah, KY 42001 +1-888-906-6358 ~43.20 miles east of 63780
  • Three Star Suburban property
  • Comp. Breakfast
From$89
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Carbondale
+1-888-749-6785
2175 Reed Station Pkwy., Carbondale, IL 62901 +1-888-749-6785 ~43.48 miles northeast of 63780
  • 3 star Rural hotel
  • Hotel has 3 floors
From$80
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Metropolis - Metropolis
+1-888-878-9982
2055 East 5th St., Metropolis, IL 62960 +1-888-878-9982 ~43.53 miles east of 63780
  • Economical Highway hotel
  • Complimentary breakfast is offered
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
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