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63780 Hotels/Accommodations

Candlewood Suites Cape Girardeau by IHG
+1-888-389-4121
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~9.95 miles northwest of 63780
  • 2-star Highway hotel
  • 85 rooms in hotel
From$69
Very good 4.0 /5 Hotel Reviews Call BookMore Details
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Courtyard by Marriott Cape Girardeau Downtown in Cape Girardeau
+1-888-675-2083
400 Broadway St., Cape Girardeau, MO 63701 ~10.05 miles north of 63780
  • Midscale Downtown property
  • Hotel has 5 floors
From$80
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East : 207 South Mount Auburn Rd.
+1-800-716-8490
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 ~10.67 miles northwest of 63780
  • Midscale Highway property
  • Check in: 15:00
From$80
Excellent 5.0 /5 Review Score Call BookMore Details
Victorian Inn & Suites : 3256 William St.
+1-800-805-5223
3256 William St., Cape Girardeau, MO 63703 ~10.74 miles northwest of 63780
  • Mid-scale Golf Course property
  • Complimentary breakfast is offered
From$79
Average 3.0 /5 Hotel Reviews Call BookMore Details
Auburn Place Hotel & Suites
+1-888-965-1860
3265 Williams St., Cape Girardeau, MO 63702 ~10.74 miles northwest of 63780
  • Three Star Highway hotel
  • 2 meeting rooms in hotel
From$58
Very good 4.5 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 - Cape Girardeau
+1-888-788-5576
3253 William St., Cape Girardeau, MO 63701 ~10.77 miles northwest of 63780
  • Midscale property
  • Access to gym on-site
From$80
Very good 4.5 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites Cape Girardeau - Cape Girardeay
+1-888-897-9207
433 Cape West Crossing, Cape Girardeay, MO 63703 ~10.80 miles northwest of 63780
  • Affordable property
  • Hotel has 4 floors
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center
+1-888-311-4278
3248 William St., Cape Girardeau, MO 63701 ~10.83 miles northwest of 63780
  • Two-star Highway hotel
  • 3 floors in property
From$66
Very good 4.0 /5 Recent Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West in Cape Girardeau
+1-888-469-4795
103 Cape West Pkwy., Cape Girardeau, MO 63701 ~10.84 miles northwest of 63780
  • Inexpensive property
  • 81 rooms in property
From$59
Average 3.0 /5 Guest Reviews Call BookMore Details
Drury Suites Cape Girardeau
+1-888-734-9421
3303 Campster Dr., Cape Girardeau, MO 63701 ~10.95 miles northwest of 63780
  • 3-star Highway hotel
  • Free breakfast available
From$85
Very good 4.5 /5 Guest Reviews Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau
+1-888-841-5292
3351 Percy Dr., Cape Girardeau, MO 63701 ~11.10 miles northwest of 63780
  • 3 star property
  • Complimentary breakfast is offered
From$59
Average 3.0 /5 Read Reviews Call BookMore Details
Drury Lodge - Cape Girardeau
+1-888-455-5160
104 South Vantage Dr., Cape Girardeau, MO 63701 ~11.11 miles northwest of 63780
  • 3-star Highway hotel
  • Free breakfast
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn
+1-888-965-8297
2011 North Kingshighway St., Cape Girardeau, MO 63701 ~13.06 miles northwest of 63780
  • Economy property
  • 2 floors in hotel
From$60
Very good 4.0 /5 Latest Reviews Call BookMore Details
TRU by Hilton Cape Girardeau
+1-888-906-6358
2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 ~14.25 miles northwest of 63780
  • Mid-scale Highway hotel
  • 90 rooms in property
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau - Jackson
+1-888-749-6785
3003 South Old Orchard Rd., Jackson, MO 63755 ~14.80 miles northwest of 63780
  • Affordable Highway property
  • Free complimentary breakfast
From$85
Very good 4.0 /5 Read Reviews Call BookMore Details
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Comfort Suites Jackson-Cape Girardeau : 2904 Old Orchard Rd.
+1-888-878-9982
2904 Old Orchard Rd., Jackson, MO 63755 ~14.91 miles northwest of 63780
  • Affordable Highway property
  • Gym / Fitness Center Available
From$65
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Suites - Jackson
+1-888-389-4485
2904 Old Orchard Rd., Jackson, 63755 United States ~14.91 miles northwest of 63780
  • High-end Highway property
  • Free complimentary breakfast
From$125
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn Cairo I-57
+1-888-389-4121
13201 Kessler Rd., Cairo, IL 62914 ~17.88 miles east of 63780
  • Three Star Highway property
  • 38 rooms in property
Super 8 by Wyndham Charleston/Sikeston East MO - Charleston
+1-888-675-2083
310 South Story, Charleston, MO 63834 ~19.03 miles southeast of 63780
  • Economy Highway property
  • 7 suites in hotel
From$42
Average 3.5 /5 Hotel Reviews Call BookMore Details
Motel 6 Sikeston Mo
+1-800-716-8490
110 South Interstate Dr., SIKESTON, MO 63801 ~19.03 miles south of 63780
  • Two-star hotel
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Best Western Plus Sikeston : 120 South Interstate Dr.
+1-800-805-5223
120 South Interstate Dr., Sikeston, MO 63801 ~19.07 miles south of 63780
  • Low Cost Highway hotel
  • Hotel has 55 rooms
From$43
Very good 4.0 /5 Review Score Call BookMore Details
Quality Inn Charleston - Sikeston - Charleston
+1-888-965-1860
102 Drake St., Charleston, MO 63834 ~19.09 miles south of 63780
  • Cheap Highway hotel
  • Check-in: 3:00PM
From$59
Average 3.0 /5 Guest Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds in Ullin
+1-888-788-5576
128 Cheekwood Lane, Ullin, IL 62992 ~19.15 miles east of 63780
  • 2-star property
  • Complimentary breakfast is offered
From$60
Average 3.0 /5 Reviews Call BookMore Details
Drury Inn & Suites Sikeston in Sikeston
+1-888-897-9207
2608 East Malone Ave., Sikeston, MO 63801 ~19.16 miles south of 63780
  • Affordable Highway property
  • Hotel has 5 floors
From$104
Very good 4.5 /5 Read Reviews Call BookMore Details
Pear Tree Inn Sikeston - Sikeston
+1-888-311-4278
2602 East Malone, Sikeston, MO 63801 ~19.16 miles south of 63780
  • Affordable Suburban property
  • Check in time: 3:00 PM
From$80
Average 3.0 /5 Review Score Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) : 100 Matthews Lane
+1-888-469-4795
100 Matthews Lane, Sikeston, MO 63801 ~19.20 miles south of 63780
  • 3-star Highway property
  • 40 sleeping rooms in hotel
From$80
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn - Sikeston
+1-888-734-9421
109 Matthews Lane, Sikeston, MO 63801 ~19.21 miles south of 63780
  • 3 star Highway property
  • Fitness center on property
From$85
Average 3.0 /5 Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston in Sikeston
+1-888-841-5292
220 South Interstate Dr., Sikeston, MO 63801 ~19.24 miles south of 63780
  • Low priced hotel
  • Gym / Fitness Center Available
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Sikeston/Miner Area : 2609 East Malone
+1-888-455-5160
2609 East Malone, Sikeston, MO 63801 ~19.30 miles south of 63780
  • Two star Convention Center property
  • Free breakfast available
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Drury Inn & Suites Jackson Missouri
+1-888-965-8297
225 Drury Lane, Jackson, MO 63755 ~20.25 miles northwest of 63780
  • Mid-scale Suburban hotel
  • Check in: 3:00 PM
From$79
Very good 4.5 /5 Guest Reviews Call BookMore Details
Hampton Inn Sikeston - Sikeston
+1-888-906-6358
1240 Commerce Dr., Sikeston, MO 63801 ~21.91 miles south of 63780
  • 3 star Rural hotel
  • Fitness center on property
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel : 115 Hospitality Dr.
+1-888-749-6785
115 Hospitality Dr., Sikeston, MO 63801 ~21.92 miles south of 63780
  • Mid-scale Rural property
  • 73 rooms in hotel
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Hotel 7 Inn Anna
+1-888-878-9982
100 Richview Dr., Anna, IL 62906 ~25.02 miles northeast of 63780
  • Low Cost hotel
From$60
Very good 4.0 /5 Read Reviews Call BookMore Details
Econo Lodge Dexter
+1-888-389-4485
913 Outer Rd., Dexter, MO 63841 ~36.64 miles southwest of 63780
  • Cheap property
  • Free comp. breakfast
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Travelodge by Wyndham Dexter
+1-888-389-4121
1608 West Business U.s. 60, Dexter, MO 63841 ~37.34 miles southwest of 63780
  • 3-star property
From$67
Very good 4.0 /5 Reviews Call BookMore Details
Train Inn
+1-888-675-2083
406 East Stoker St., Carbondale, IL 62901 ~41.10 miles north of 63780
  • 3-star Suburban property
  • Hotel has a green policy See policy
From$50
Very good 4.0 /5 Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino
+1-800-716-8490
100 East Front St., Metropolis, IL 62960 ~41.18 miles east of 63780
  • High end property
  • Check-in time: 16:00
From$160
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Metropolis : 203 East Front St.
+1-800-805-5223
203 East Front St., Metropolis, IL 62960 ~41.23 miles east of 63780
  • Low Cost Riverfront hotel
  • Check in time: 3:00PM
From$45
Average 3.0 /5 Guest Reviews Call BookMore Details
Home2 Suites by Hilton Carbondale in Carbondale
+1-888-965-1860
200 West Elm St., Carbondale, IL 62901 ~41.29 miles north of 63780
  • Three Star Downtown property
  • Fitness + Health Center
From$99
Very good 4.0 /5 Latest Reviews Call BookMore Details
University Inn of Carbondale - Carbondale
+1-888-788-5576
2400 West Main St., Carbondale, IL 62901 ~41.35 miles north of 63780
  • Three Star hotel
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Carbondale Value Inn & Suites in Carbondale
+1-888-897-9207
700 East Main St., Carbondale, IL 62901 ~41.77 miles north of 63780
  • Cheap Downtown hotel
  • Hotel has 41 rooms
From$54
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Carbondale in Carbondale
+1-888-311-4278
1180 East Main St., Carbondale, IL 62901 ~42.08 miles north of 63780
  • Inexpensive property
  • 63 sleeping rooms in hotel
From$58
Average 3.0 /5 Hotel Reviews Call BookMore Details
Econo Lodge
+1-888-469-4795
1415 East 5th St., Metropolis, IL 62960 ~42.28 miles east of 63780
  • Economical hotel
From$60
Terrible 1.0 /5 Latest Reviews Call BookMore Details
Pear Tree Inn Paducah
+1-888-734-9421
5006 Hinkleville Rd., Paducah, KY 42001 ~42.53 miles east of 63780
  • 2-star Suburban hotel
  • Free breakfast available
From$55
Very good 4.0 /5 Latest Reviews Call BookMore Details
Best Western Saluki Inn
+1-888-841-5292
801 North Giant City Rd., Carbondale, IL 62902 ~42.55 miles north of 63780
  • Mid-scale Downtown property
  • 65 sleeping rooms in hotel
From$79
Average 3.0 /5 Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale in Murphysboro
+1-888-455-5160
128 East Walnut St., Murphysboro, IL 62966 ~42.58 miles north of 63780
  • Low priced property
Quality Inn Carbondale University Area in Carbondale
+1-888-965-8297
1415 East Main St., Carbondale, IL 62901 ~42.65 miles north of 63780
  • Midscale Suburban hotel
  • Check-in: 3:00pm
Residence Inn by Marriott Paducah
+1-888-906-6358
3900 Coleman Crossing Circle, Paducah, KY 42001 ~43.20 miles east of 63780
  • Three Star Suburban hotel
  • Gym / Fitness Center Available
From$89
Very good 4.0 /5 Reviews Call BookMore Details
Hampton Inn Carbondale
+1-888-749-6785
2175 Reed Station Pkwy., Carbondale, IL 62901 ~43.48 miles northeast of 63780
  • Three Star Rural property
  • 3 floors in hotel
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Metropolis in Metropolis
+1-888-878-9982
2055 East 5th St., Metropolis, IL 62960 ~43.53 miles east of 63780
  • Economy Highway property
  • Complimentary breakfast is offered
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details

Next: Show All Available 63780 Hotels with Pricing

Graph: Upcoming 20 Days of 63780 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cape Girardeau, MO discounts available. The chart reflects the cheapest Cape Girardeau hotel for each day and each star rating category.

FAQs about hotels near 63780

What are the most favored hotels near 63780?

Hampton Inn Cape Girardeau I 55 East, Auburn Place Hotel & Suites and Holiday Inn Express & Suites Cape Girardeau I 55 are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels near 63780?

Comfort Suites, Harrah's Metropolis Hotel & Casino and Courtyard by Marriott Cape Girardeau Downtown are the top 3 luxury hotels near 63780.

What hotels are closest to the area of 63780?

Candlewood Suites Cape Girardeau by IHG, Courtyard by Marriott Cape Girardeau Downtown, and Hampton Inn Cape Girardeau I 55 East are the properties closest to 63780.

How much does a cheap hotel near 63780 cost per night?

In the last year, a 2 star hotel near 63780 can be as cheap as $92.03 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 63780 cost per night?

In the last year, the average 3 star hotel near 63780 has been $115.99 per night. (based on HotelPlanner prices)

How much does a higher-end hotel near 63780 cost?

In the last year, the average 4 star hotel near 63780 has been $132.74 per night. (based on HotelPlanner prices)

What are the best independent hotels near 63780?

Auburn Place Hotel & Suites, Drury Suites Cape Girardeau and Travel Inn & Suites - Sikeston are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 63780?

Courtyard by Marriott Cape Girardeau Downtown, Residence Inn by Marriott Paducah and Fairfield Inn & Suites Cape Girardeau are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 63780?

Quality Inn, Comfort Suites Jackson-Cape Girardeau and Quality Inn Charleston - Sikeston are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular Best Western hotels near 63780?

Best Western Plus Sikeston and Best Western Saluki Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the best IHG hotels near 63780?

Holiday Inn Express & Suites Cape Girardeau I 55, Candlewood Suites Cape Girardeau by IHG and Holiday Inn Express & Suites Sikeston An Ihg Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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