Star Rating
Hotel Name
Price Range (USD) to
Amenities
+ More

63780 Hotels & Accommodations

Candlewood Suites Cape Girardeau, an IHG Hotel in Cape Girardeau
+1-888-389-4121
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~9.95 miles northwest of 63780
  • Two star Highway property
  • Hotel has 4 floors
From$69
Very Good 4.0 /5 Review Score Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 63780" Get Alexa Skill →
Courtyard by Marriott Cape Girardeau Downtown in Cape Girardeau
+1-888-675-2083
400 Broadway St., Cape Girardeau, MO 63701 ~10.05 miles north of 63780
  • 3-star Downtown hotel
  • Check-in: 3:00 pm
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East
+1-800-716-8490
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 ~10.67 miles northwest of 63780
  • Midscale Highway property
  • 4 floors in hotel
From$80
Excellent 5.0 /5 Read Reviews Call BookMore Details
Victorian Inn & Suites - Cape Girardeau
+1-800-805-5223
3256 William St., Cape Girardeau, MO 63703 ~10.74 miles northwest of 63780
  • Three Star Golf Course hotel
  • Hotel has 2 floors
From$79
Average 3.0 /5 Recent Reviews Call BookMore Details
Auburn Place Hotel & Suites
+1-888-965-1860
3265 Williams St., Cape Girardeau, MO 63702 ~10.74 miles northwest of 63780
  • Affordable Highway property
  • Hotel has 2 floors
From$58
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 - Cape Girardeau
+1-888-788-5576
3253 William St., Cape Girardeau, MO 63701 ~10.77 miles northwest of 63780
  • 3-star property
  • 102 sleeping rooms in hotel
From$80
Very Good 4.5 /5 Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center
+1-888-897-9207
3248 William St., Cape Girardeau, MO 63701 ~10.83 miles northwest of 63780
  • 2-star Highway hotel
  • Check-in time: 3:00 pm
From$66
Very Good 4.0 /5 Review Score Call BookMore Details
Pear Tree Inn Cape Girardeau West in Cape Girardeau
+1-888-311-4278
103 Cape West Pkwy., Cape Girardeau, MO 63701 ~10.84 miles northwest of 63780
  • Two-star property
  • Hotel has 3 floors
From$59
Average 3.0 /5 Reviews Call BookMore Details
Drury Suites Cape Girardeau
+1-888-469-4795
3303 Campster Dr., Cape Girardeau, MO 63701 ~10.95 miles northwest of 63780
  • 3 star Highway hotel
  • Hotel has 79 suites
From$85
Very Good 4.5 /5 Read Reviews Call BookMore Details
Drury Lodge
+1-888-734-9421
104 South Vantage Dr., Cape Girardeau, MO 63701 ~11.11 miles northwest of 63780
  • 3 star Highway property
  • Fitness + Health Center
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau in Cape Girardeau
+1-888-841-5292
3351 Percy Dr., Cape Girardeau, MO 63701 ~11.13 miles northwest of 63780
  • 3-star property
  • Hotel has 168 rooms
From$59
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn in Cape Girardeau
+1-888-455-5160
2011 North Kingshighway St., Cape Girardeau, MO 63701 ~13.06 miles northwest of 63780
  • Economical property
  • Hotel has 2 floors
From$60
Very Good 4.0 /5 Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau - Jackson
+1-888-965-8297
3003 South Old Orchard Rd., Jackson, MO 63755 ~14.80 miles northwest of 63780
  • Three Star Highway hotel
  • Hotel has 80 rooms
From$85
Very Good 4.0 /5 Read Reviews Call BookMore Details
Comfort Suites Jackson-Cape Girardeau : 2904 Old Orchard Rd.
+1-888-906-6358
2904 Old Orchard Rd., Jackson, MO 63755 ~14.91 miles northwest of 63780
  • Midscale Highway property
  • Hotel has 64 rooms
From$65
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn Cairo I-57
+1-888-749-6785
13201 Kessler Rd., Cairo, IL 62914 ~17.88 miles east of 63780
  • Midscale Highway property
  • Check-in time: 3 pm
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 63780" Get Alexa Skill →
Super 8 by Wyndham Charleston MO - Charleston
+1-888-878-9982
310 South Story, Charleston, MO 63834 ~19.03 miles southeast of 63780
  • Two star Highway hotel
  • 60 rooms in hotel
From$42
Average 3.5 /5 Read Reviews Call BookMore Details
Motel 6 Sikeston Mo : 110 South Interstate Dr.
+1-888-389-4485
110 South Interstate Dr., SIKESTON, MO 63801 ~19.03 miles south of 63780
  • Two-star hotel
From$60
Average 3.0 /5 Reviews Call BookMore Details
Best Western Plus Sikeston : 120 South Interstate Dr.
+1-888-389-4121
120 South Interstate Dr., Sikeston, MO 63801 ~19.07 miles south of 63780
  • Low-priced Highway property
  • 55 rooms in property
From$43
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Quality Inn - Charleston
+1-888-675-2083
102 Drake St., Charleston, MO 63834 ~19.09 miles south of 63780
  • Cheap Highway hotel
  • 2 floors in property
From$59
Average 3.0 /5 Guest Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds in Ullin
+1-800-716-8490
128 Cheekwood Lane, Ullin, IL 62992 ~19.15 miles east of 63780
  • Economy property
  • 40 sleeping rooms in hotel
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Drury Inn & Suites Sikeston - Sikeston
+1-800-805-5223
2608 East Malone Ave., Sikeston, MO 63801 ~19.16 miles south of 63780
  • Three Star Highway hotel
  • Check in time: 3:00 PM
From$104
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Pear Tree Inn Sikeston
+1-888-965-1860
2602 East Malone, Sikeston, MO 63801 ~19.16 miles south of 63780
  • 3 star Suburban hotel
  • Hotel has 4 floors
From$80
Average 3.0 /5 Reviews Call BookMore Details
Travel Inn & Suites : 100 Matthews Lane
+1-888-788-5576
100 Matthews Lane, Sikeston, MO 63801 ~19.20 miles south of 63780
  • Three Star Highway hotel
  • Check-in: 3:00 PM
From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Comfort Inn in Sikeston
+1-888-897-9207
109 Matthews Lane, Sikeston, MO 63801 ~19.21 miles south of 63780
  • Three Star Highway property
  • 64 rooms in hotel
From$85
Average 3.0 /5 Hotel Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston : 220 South Interstate Dr.
+1-888-311-4278
220 South Interstate Dr., Sikeston, MO 63801 ~19.24 miles south of 63780
  • Cheap hotel
  • Access to gym on-site
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Sikeston/Miner Area : 2609 East Malone
+1-888-469-4795
2609 East Malone, Sikeston, MO 63801 ~19.30 miles south of 63780
  • Economy Convention Center property
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Drury Inn & Suites Jackson Missouri in Jackson
+1-888-734-9421
225 Drury Lane, Jackson, MO 63755 ~20.25 miles northwest of 63780
  • 3 star Suburban hotel
  • Hotel has 4 floors
From$79
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Hampton Inn Sikeston
+1-888-841-5292
1240 Commerce Dr., Sikeston, MO 63801 ~21.91 miles south of 63780
  • Midscale Rural hotel
  • 92 rooms in property
From$80
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel - Sikeston
+1-888-455-5160
115 Hospitality Dr., Sikeston, MO 63801 ~21.92 miles south of 63780
  • Midscale Rural property
  • 3 floors in hotel
From$94
Very Good 4.0 /5 Review Score Call BookMore Details
Hotel 7 Inn Anna
+1-888-965-8297
100 Richview Dr., Anna, IL 62906 ~25.02 miles northeast of 63780
  • Economical hotel
From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Econo Lodge Dexter - Dexter
+1-888-906-6358
913 Outer Rd., Dexter, MO 63841 ~36.64 miles southwest of 63780
  • Low priced property
  • 38 rooms in hotel
From$60
Average 3.0 /5 Reviews Call BookMore Details
Travelodge by Wyndham Dexter - Dexter
+1-888-749-6785
1608 West Business U.s. 60, Dexter, MO 63841 ~37.34 miles southwest of 63780
  • Midscale hotel
From$67
Very Good 4.0 /5 Read Reviews Call BookMore Details
Train Inn : 406 East Stoker St.
+1-888-878-9982
406 East Stoker St., Carbondale, IL 62901 ~41.10 miles north of 63780
  • Mid-scale Suburban property
  • Airport shuttle available
From$50
Very Good 4.0 /5 Review Score Call BookMore Details
Harrah's Metropolis Hotel & Casino
+1-888-389-4485
100 East Front St., Metropolis, IL 62960 ~41.18 miles east of 63780
  • Four-star hotel
  • Hotel has 12 suites
From$160
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Metropolis in Metropolis
+1-888-389-4121
203 East Front St., Metropolis, IL 62960 ~41.23 miles east of 63780
  • 2-star Riverfront property
  • 8 suites in property
From$45
Average 3.0 /5 Review Score Call BookMore Details
Home2 Suites by Hilton Carbondale - Carbondale
+1-888-675-2083
200 West Elm St., Carbondale, IL 62901 ~41.29 miles north of 63780
  • 3 star Downtown property
  • 4 floors in hotel
From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
University Inn of Carbondale in Carbondale
+1-800-716-8490
2400 West Main St., Carbondale, IL 62901 ~41.35 miles north of 63780
  • Affordable property
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Carbondale Value Inn & Suites : 700 East Main St.
+1-800-805-5223
700 East Main St., Carbondale, IL 62901 ~41.77 miles north of 63780
  • 2 star Downtown hotel
  • Comp. Breakfast
From$54
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Carbondale
+1-888-965-1860
1180 East Main St., Carbondale, IL 62901 ~42.08 miles north of 63780
  • 2 star hotel
  • 63 rooms in hotel
From$58
Average 3.0 /5 Guest Reviews Call BookMore Details
Econo Lodge in Metropolis
+1-888-788-5576
1415 East 5th St., Metropolis, IL 62960 ~42.28 miles east of 63780
  • Economical hotel
  • Check-in: 11:00
From$60
Not Good 1.0 /5 Review Score Call BookMore Details
Pear Tree Inn Paducah - Paducah
+1-888-897-9207
5006 Hinkleville Rd., Paducah, KY 42001 ~42.53 miles east of 63780
  • Low-priced Suburban hotel
  • Comp. Breakfast
From$55
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Best Western Saluki Inn : 801 North Giant City Rd.
+1-888-311-4278
801 North Giant City Rd., Carbondale, IL 62902 ~42.55 miles north of 63780
  • Three Star Downtown hotel
  • 2 suites in hotel
From$79
Average 3.0 /5 Latest Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale in Murphysboro
+1-888-469-4795
128 East Walnut St., Murphysboro, IL 62966 ~42.58 miles north of 63780
  • Low Cost hotel
  • Check-in: 14:00
Quality Inn Carbondale University Area - Carbondale
+1-888-734-9421
1415 East Main St., Carbondale, IL 62901 ~42.65 miles north of 63780
  • Midscale Suburban property
  • 64 rooms in property
Residence Inn by Marriott Paducah
+1-888-841-5292
3900 Coleman Crossing Circle, Paducah, KY 42001 ~43.20 miles east of 63780
  • Midscale Suburban hotel
  • Fitness / Gym is on-site
From$89
Very Good 4.0 /5 Review Score Call BookMore Details
Hampton Inn Carbondale : 2175 Reed Station Pkwy.
+1-888-455-5160
2175 Reed Station Pkwy., Carbondale, IL 62901 ~43.48 miles northeast of 63780
  • Affordable Rural property
  • 3 floors in property
From$80
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Metropolis in Metropolis
+1-888-965-8297
2055 East 5th St., Metropolis, IL 62960 ~43.53 miles east of 63780
  • 2 star Highway property
  • 63 rooms in hotel
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Metropolis I-24 in Metropolis
+1-888-906-6358
2118 East 5th St., Metropolis, IL 62960 ~43.57 miles east of 63780
  • Midscale property
  • Check-in time: 11:00
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Carbondale-Conference Center, an IHG Hotel
+1-888-749-6785
2300 Reed Station Pkwy., Carbondale, IL 62901 ~43.63 miles northeast of 63780
  • Mid-scale Rural hotel
  • 2 suites in property
From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Perryville in Perryville
+1-888-878-9982
1119 Vincent Dr., Perryville, MO 63775 ~43.66 miles northwest of 63780
  • 2 star Highway property
  • 64 rooms in hotel
From$59
Very Good 4.0 /5 Hotel Reviews Call BookMore Details

Next: Show All Available 63780 Hotels with Pricing

Graph: Upcoming 20 Days of 63780 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cape Girardeau, MO discounts available. The chart reflects the cheapest Cape Girardeau hotel for each day and each star rating category.

FAQs about hotels near 63780

What are the most favored hotels near 63780?

Hampton Inn Cape Girardeau I 55 East, Auburn Place Hotel & Suites and Holiday Inn Express & Suites Cape Girardeau I 55 are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels near 63780?

Harrah's Metropolis Hotel & Casino, Courtyard by Marriott Cape Girardeau Downtown and Hampton Inn Cape Girardeau I 55 East are the top 3 luxury hotels near 63780.

What hotels are closest to the area of 63780?

Candlewood Suites Cape Girardeau, an IHG Hotel, Courtyard by Marriott Cape Girardeau Downtown, and Hampton Inn Cape Girardeau I 55 East are the properties closest to 63780.

How much does a cheap hotel near 63780 cost per night?

In the last year, a 2 star hotel near 63780 can be as cheap as $91.66 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 63780 cost per night?

In the last year, the average 3 star hotel near 63780 has been $119.79 per night. (based on HotelPlanner prices)

What are the best independent hotels near 63780?

Auburn Place Hotel & Suites, Drury Suites Cape Girardeau and Travel Inn & Suites are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 63780?

Courtyard by Marriott Cape Girardeau Downtown and Residence Inn by Marriott Paducah are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 63780?

Quality Inn, Quality Inn & Suites Metropolis I-24 and Comfort Suites Jackson-Cape Girardeau are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular Best Western hotels near 63780?

Best Western Plus Sikeston and Best Western Saluki Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the best IHG hotels near 63780?

Holiday Inn Express & Suites Cape Girardeau I 55, Candlewood Suites Cape Girardeau, an IHG Hotel and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Back to Top