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63780 Hotels/Motels & Accommodations

Candlewood Suites Cape Girardeau by IHG
+1-888-389-4121
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~9.94 miles northwest of 63780
  • Economical Highway property
  • 4 floors in property
From$69
Very good 4.0 /5 Reviews Call BookMore Details
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Courtyard by Marriott Cape Girardeau Downtown - Cape Girardeau
+1-888-675-2083
400 Broadway St., Cape Girardeau, MO 63701 ~10.03 miles north of 63780
  • Affordable Downtown property
  • 78 sleeping rooms in hotel
From$80
Very good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East : 207 South Mount Auburn Rd.
+1-800-716-8490
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 ~10.65 miles northwest of 63780
  • 3-star Highway hotel
  • Check-in: 15:00
From$80
Excellent 5.0 /5 Read Reviews Call BookMore Details
Victorian Inn & Suites : 3256 William St.
+1-800-805-5223
3256 William St., Cape Girardeau, MO 63703 ~10.72 miles northwest of 63780
  • 3-star Golf Course hotel
  • 133 sleeping rooms in hotel
From$79
Average 3.0 /5 Recent Reviews Call BookMore Details
Auburn Place Hotel & Suites
+1-888-965-1860
3265 Williams St., Cape Girardeau, MO 63702 ~10.73 miles northwest of 63780
  • 3-star Highway hotel
  • Fitness / Gym is on-site
From$58
Very good 4.5 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 by Ihg
+1-888-788-5576
3253 William St., Cape Girardeau, MO 63701 ~10.75 miles northwest of 63780
  • 3-star hotel
  • Fitness center on property
From$80
Very good 4.5 /5 Review Score Call BookMore Details
Fairfield Inn & Suites Cape Girardeau - Cape Girardeay
+1-888-897-9207
433 Cape West Crossing, Cape Girardeay, MO 63703 ~10.79 miles northwest of 63780
  • 3-star hotel
  • 4 floors in hotel
From$80
Average 3.0 /5 Review Score Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center : 3248 William St.
+1-888-311-4278
3248 William St., Cape Girardeau, MO 63701 ~10.82 miles northwest of 63780
  • Low priced Highway property
  • Check in: 3:00 pm
From$66
Very good 4.0 /5 Recent Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West
+1-888-469-4795
103 Cape West Pkwy., Cape Girardeau, MO 63701 ~10.83 miles northwest of 63780
  • Cheap property
  • Hotel has an eco-friendly policy Read more
From$59
Average 3.0 /5 Guest Reviews Call BookMore Details
Drury Suites Cape Girardeau in Cape Girardeau
+1-888-734-9421
3303 Campster Dr., Cape Girardeau, MO 63701 ~10.94 miles northwest of 63780
  • Affordable Highway hotel
  • 79 suites in hotel
From$85
Very good 4.5 /5 Review Score Call BookMore Details
Drury Lodge : 104 South Vantage Dr.
+1-888-841-5292
104 South Vantage Dr., Cape Girardeau, MO 63701 ~11.10 miles northwest of 63780
  • Affordable Highway hotel
  • Free complimentary breakfast
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn : 2011 North Kingshighway St.
+1-888-455-5160
2011 North Kingshighway St., Cape Girardeau, MO 63701 ~13.04 miles northwest of 63780
  • Two-star property
  • 2 floors in property
From$60
Very good 4.0 /5 Hotel Reviews Call BookMore Details
TRU by Hilton Cape Girardeau
+1-888-965-8297
2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 ~14.23 miles northwest of 63780
  • 3 star Highway hotel
  • 4 floors in property
From$80
Average 3.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau : 3003 South Old Orchard Rd.
+1-888-906-6358
3003 South Old Orchard Rd., Jackson, MO 63755 ~14.79 miles northwest of 63780
  • 3-star Highway property
  • 80 rooms in property
From$85
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Suites
+1-888-749-6785
2904 Old Orchard Rd., Jackson, MO 63755 ~14.89 miles northwest of 63780
  • Mid-scale Highway property
  • Check-in time: 3:00 PM
From$80
Average 3.0 /5 Review Score Call BookMore Details
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Quality Inn Cairo I-57 in Cairo
+1-888-878-9982
13201 Kessler Rd., Cairo, IL 62914 ~17.84 miles east of 63780
  • Midscale Highway hotel
  • Check-in: 3 pm
Super 8 by Wyndham Charleston/Sikeston East MO
+1-888-389-4485
310 South Story, Charleston, MO 63834 ~18.99 miles southeast of 63780
  • Low Cost Highway property
  • Free breakfast
From$42
Average 3.5 /5 Hotel Reviews Call BookMore Details
Motel 6 Sikeston Mo in SIKESTON
+1-888-389-4121
110 South Interstate Dr., SIKESTON, MO 63801 ~19.00 miles south of 63780
  • Two-star property
From$60
Average 3.0 /5 Review Score Call BookMore Details
Best Western Plus Sikeston - Sikeston
+1-888-675-2083
120 South Interstate Dr., Sikeston, MO 63801 ~19.04 miles south of 63780
  • Low Cost Highway hotel
  • Comp. Breakfast
From$43
Very good 4.0 /5 Read Reviews Call BookMore Details
Quality Inn Charleston - Sikeston : 102 Drake St.
+1-800-716-8490
102 Drake St., Charleston, MO 63834 ~19.06 miles south of 63780
  • Economical Highway hotel
  • 40 rooms in hotel
From$59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds
+1-800-805-5223
128 Cheekwood Lane, Ullin, IL 62992 ~19.13 miles east of 63780
  • 2 star hotel
  • 2 floors in hotel
From$60
Average 3.0 /5 Reviews Call BookMore Details
Pear Tree Inn Sikeston in Sikeston
+1-888-965-1860
2602 East Malone, Sikeston, MO 63801 ~19.13 miles south of 63780
  • Affordable Suburban hotel
  • Check-in: 3:00 PM
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
+1-888-788-5576
100 Matthews Lane, Sikeston, MO 63801 ~19.17 miles south of 63780
  • Affordable Highway property
  • 2 floors in hotel
From$80
Very good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn in Sikeston
+1-888-897-9207
109 Matthews Lane, Sikeston, MO 63801 ~19.18 miles south of 63780
  • 3-star Highway property
  • Check-in time: 11:00
From$85
Average 3.0 /5 Latest Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston
+1-888-311-4278
220 South Interstate Dr., Sikeston, MO 63801 ~19.21 miles south of 63780
  • Inexpensive hotel
  • Gym / Fitness Center Available
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Sikeston/Miner Area
+1-888-469-4795
2609 East Malone, Sikeston, MO 63801 ~19.27 miles south of 63780
  • Low-priced Convention Center property
  • Free comp. breakfast
From$60
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn Sikeston : 1240 Commerce Dr.
+1-888-734-9421
1240 Commerce Dr., Sikeston, MO 63801 ~21.87 miles south of 63780
  • Mid-scale Rural property
  • 92 rooms in hotel
From$80
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel - Sikeston
+1-888-841-5292
115 Hospitality Dr., Sikeston, MO 63801 ~21.89 miles south of 63780
  • Affordable Rural hotel
  • Fitness center on property
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Hotel 7 Inn Anna
+1-888-455-5160
100 Richview Dr., Anna, IL 62906 ~25.00 miles northeast of 63780
  • 2-star property
From$60
Very good 4.0 /5 Latest Reviews Call BookMore Details
Econo Lodge Dexter : 913 Outer Rd.
+1-888-965-8297
913 Outer Rd., Dexter, MO 63841 ~36.54 miles southwest of 63780
  • Two-star property
  • Check-in: 11:00
From$60
Average 3.0 /5 Review Score Call BookMore Details
Travelodge by Wyndham Dexter : 1608 West Business U.s. 60
+1-888-906-6358
1608 West Business U.s. 60, Dexter, MO 63841 ~37.23 miles southwest of 63780
  • Midscale hotel
  • Check in: 4
From$67
Very good 4.0 /5 Guest Reviews Call BookMore Details
Train Inn in Carbondale
+1-888-749-6785
406 East Stoker St., Carbondale, IL 62901 ~41.06 miles north of 63780
  • Midscale Suburban hotel
  • Airport shuttle provided
From$50
Very good 4.0 /5 Read Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destinatio in Metropolis
+1-888-878-9982
100 East Front St., Metropolis, IL 62960 ~41.12 miles east of 63780
  • High end property
  • 12 suites in hotel
From$160
Very good 4.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Metropolis - Metropolis
+1-888-389-4485
203 East Front St., Metropolis, IL 62960 ~41.16 miles east of 63780
  • Economical Riverfront hotel
  • 117 rooms in hotel
From$45
Average 3.0 /5 Review Score Call BookMore Details
Home2 Suites by Hilton Carbondale - Carbondale
+1-888-389-4121
200 West Elm St., Carbondale, IL 62901 ~41.25 miles north of 63780
  • 3 star Downtown property
  • Free complimentary breakfast
From$99
Very good 4.0 /5 Guest Reviews Call BookMore Details
University Inn of Carbondale : 2400 West Main St.
+1-888-675-2083
2400 West Main St., Carbondale, IL 62901 ~41.31 miles north of 63780
  • Midscale hotel
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Carbondale Value Inn & Suites : 700 East Main St.
+1-800-716-8490
700 East Main St., Carbondale, IL 62901 ~41.73 miles north of 63780
  • Economy Downtown hotel
  • Check-in: 3:00pm
From$54
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Carbondale : 1180 East Main St.
+1-800-805-5223
1180 East Main St., Carbondale, IL 62901 ~42.04 miles north of 63780
  • Low-priced hotel
  • 63 sleeping rooms in hotel
From$58
Average 3.0 /5 Review Score Call BookMore Details
Econo Lodge - Metropolis
+1-888-965-1860
1415 East 5th St., Metropolis, IL 62960 ~42.21 miles east of 63780
  • 2-star property
  • Check in: 11:00
From$60
Terrible 1.0 /5 Latest Reviews Call BookMore Details
Pear Tree Inn Paducah in Paducah
+1-888-788-5576
5006 Hinkleville Rd., Paducah, KY 42001 ~42.44 miles east of 63780
  • Low-priced Suburban hotel
  • Check-in: 3:00 PM
From$55
Very good 4.0 /5 Guest Reviews Call BookMore Details
Best Western Saluki Inn - Carbondale
+1-888-897-9207
801 North Giant City Rd., Carbondale, IL 62902 ~42.52 miles north of 63780
  • Midscale Downtown property
  • 65 sleeping rooms in hotel
From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale
+1-888-311-4278
128 East Walnut St., Murphysboro, IL 62966 ~42.53 miles north of 63780
  • 2 star property
  • 39 rooms in hotel
Quality Inn Carbondale University Area
+1-888-469-4795
1415 East Main St., Carbondale, IL 62901 ~42.61 miles north of 63780
  • Midscale Suburban property
  • Free comp. breakfast
Residence Inn by Marriott Paducah in Paducah
+1-888-734-9421
3900 Coleman Crossing Circle, Paducah, KY 42001 ~43.10 miles east of 63780
  • Midscale Suburban hotel
  • Access to gym on-site
From$89
Very good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Carbondale
+1-888-841-5292
2175 Reed Station Pkwy., Carbondale, IL 62901 ~43.44 miles northeast of 63780
  • Three Star Rural hotel
  • Free breakfast available
From$80
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Metropolis in Metropolis
+1-888-455-5160
2055 East 5th St., Metropolis, IL 62960 ~43.47 miles east of 63780
  • Economical Highway hotel
  • Free comp. breakfast
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites Metropolis I-24
+1-888-965-8297
2118 East 5th St., Metropolis, IL 62960 ~43.50 miles east of 63780
  • Mid-scale property
From$80
Very good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Carbondale Conference Center An Ihg Hotel
+1-888-906-6358
2300 Reed Station Pkwy., Carbondale, IL 62901 ~43.59 miles northeast of 63780
  • Midscale Rural hotel
  • 5 floors in hotel
From$99
Very good 4.0 /5 Read Reviews Call BookMore Details
Motel 6 Metropolis Il
+1-888-749-6785
2119 East 5th St., Metropolis, IL 62960 ~43.62 miles east of 63780
  • Cheap property
  • Check in time: 11:00 AM
From$60
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Perryville - Perryville
+1-888-878-9982
1119 Vincent Dr., Perryville, MO 63775 ~43.64 miles northwest of 63780
  • Two star Highway property
  • Check in time: 3:00pm
From$59
Very good 4.0 /5 Read Reviews Call BookMore Details

Next: Show All Available 63780 Hotels with Pricing

Graph: Upcoming 20 Days of 63780 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cape Girardeau, MO discounts available. The chart reflects the cheapest Cape Girardeau hotel for each day and each star rating category.

FAQs about hotels near 63780

What are the most favored hotels near 63780?

Hampton Inn Cape Girardeau I 55 East, Auburn Place Hotel & Suites and Holiday Inn Express & Suites Cape Girardeau I 55 by Ihg are the best rated hotels based on customer reviews in the last 365 days.

What hotels are closest to the area of 63780?

Candlewood Suites Cape Girardeau by IHG, Courtyard by Marriott Cape Girardeau Downtown, and Hampton Inn Cape Girardeau I 55 East are the properties closest to 63780.

How much does a cheap hotel near 63780 cost per night?

In the last year, a 2 star hotel near 63780 can be as cheap as $92.07 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 63780 cost per night?

In the last year, the average 3 star hotel near 63780 has been $116.67 per night. (based on HotelPlanner prices)

What are the best independent hotels near 63780?

Auburn Place Hotel & Suites, Drury Suites Cape Girardeau and Travel Inn & Suites - Sikeston are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 63780?

Courtyard by Marriott Cape Girardeau Downtown, Residence Inn by Marriott Paducah and Fairfield Inn & Suites Cape Girardeau are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 63780?

Quality Inn, Quality Inn & Suites Metropolis I-24 and Quality Inn Charleston - Sikeston are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular Best Western hotels near 63780?

Best Western Plus Sikeston and Best Western Saluki Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the best IHG hotels near 63780?

Holiday Inn Express & Suites Cape Girardeau I 55 by Ihg, Candlewood Suites Cape Girardeau by IHG and Holiday Inn Carbondale Conference Center An Ihg Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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