63781 Hotels, Motels & Accommodations

Super 8 by Wyndham Perryville - Perryville 1119 Vincent Dr., Perryville, MO 63775 Call ~11.20 miles north of 63781
  • Economy Highway hotel
  • 5 suites in property
From$59
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Perryville - Perryville 1500 Liberty St., Perryville, MO 63775 Call ~11.27 miles north of 63781
  • Cheap Highway hotel
  • Comp. Breakfast
From$60
Average 3.5 /5 Guest Reviews Call BookMore Details
Comfort Suites 2904 Old Orchard Rd., Jackson, MO 63755 Call ~21.91 miles southeast of 63781
  • Affordable Highway hotel
  • Fitness + Health Center
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau 3003 South Old Orchard Rd., Jackson, MO 63755 Call ~21.92 miles southeast of 63781
  • Three Star Highway hotel
  • Free breakfast
From$85
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
TRU by Hilton Cape Girardeau in Cape Girardeau 2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 Call ~22.66 miles southeast of 63781
  • 3-star Highway property
  • 4 floors in property
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Arrowrock Inn 17030 New Bremen Rd., Ste Genevieve, MO 63670 Call ~23.37 miles north of 63781
  • Cheap Rural property
  • 4 suites in property
From$49
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn Cape Girardeau North - Cape Girardeau 2011 North Kingshighway St., Cape Girardeau, MO 63701 Call ~23.93 miles southeast of 63781
  • 2-star property
  • Check in: 3:00 PM
From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Drury Lodge - Cape Girardeau 104 South Vantage Dr., Cape Girardeau, MO 63701 Call ~25.35 miles southeast of 63781
  • 3 star Highway property
  • Check in: 3:00pm
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Drury Suites Cape Girardeau 3303 Campster Dr., Cape Girardeau, MO 63701 Call ~25.45 miles southeast of 63781
  • 3-star Highway property
  • 79 suites in hotel
From$85
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites Cape Girardeau : 433 Cape West Crossing 433 Cape West Crossing, Cape Girardeay, MO 63703 Call ~25.58 miles southeast of 63781
  • 3-star property
  • Comp. Breakfast
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 by Ihg in Cape Girardeau 3253 William St., Cape Girardeau, MO 63701 Call ~25.67 miles southeast of 63781
  • 3-star hotel
  • Gym is available on property
From$80
Very Good 4.5 /5 Reviews Call BookMore Details
Auburn Place Hotel & Suites in Cape Girardeau 3265 Williams St., Cape Girardeau, MO 63702 Call ~25.75 miles southeast of 63781
  • 3-star Highway property
  • 2 floors in property
From$58
Very Good 4.5 /5 Review Score Call BookMore Details
Victorian Inn & Suites in Cape Girardeau 3256 William St., Cape Girardeau, MO 63703 Call ~25.76 miles southeast of 63781
  • Affordable Golf Course hotel
  • Check in: 3:00 pm
From$79
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn Cape Girardeau I 55 East in Cape Girardeau 207 South Mount Auburn Rd., Cape Girardeau, MO 63703 Call ~25.76 miles southeast of 63781
  • Midscale Highway property
  • Free breakfast
From$80
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Candlewood Suites Cape Girardeau by IHG in Cape Girardeau 485 South Mount Auburn Rd., Cape Girardeau, MO 65703 Call ~26.41 miles southeast of 63781
  • Cheap Highway property
  • Check in: 3:00PM
From$69
Very Good 4.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Chester Il in Chester 2150 State St., Chester, IL 62233 Call ~26.70 miles north of 63781
  • Affordable Rural property
  • Fitness / Gym is on-site
From$69
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown in Cape Girardeau 400 Broadway St., Cape Girardeau, MO 63701 Call ~27.74 miles southeast of 63781
  • Mid-scale Downtown property
  • Check in time: 3:00 pm
From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Microtel Inn & Suites by Wyndham Sainte Genevieve in Ste. Genevieve 21958 State Highway 32, Ste. Genevieve, MO 63670 Call ~29.79 miles north of 63781
  • Inexpensive Highway property
  • Check-in time: 3:00 pm
From$50
Average 3.0 /5 Latest Reviews Call BookMore Details
Baymont Inn and Suites by Wyndham Farmington, MO 1625 West Columbia St., Farmington, MO 63640 Call ~32.20 miles west of 63781
  • Midscale Highway hotel
  • 3 meeting rooms in property
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn Farmington 1400 West Liberty St., Farmington, MO 63640 Call ~32.47 miles west of 63781
  • Midscale Rural hotel
  • Check in: 11:00
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Farmington by IHG 820 Market St., Farmington, MO 63640 Call ~32.61 miles northwest of 63781
  • Midscale Rural hotel
  • Check in: 3:00pm
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Farmington : 930 Valley Creek Dr. 930 Valley Creek Dr., Farmington, MO 63640 Call ~32.71 miles northwest of 63781
  • Low-priced hotel
  • Hotel has 60 rooms
From$49
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Hampton Inn Farmington 850 Valley Creek Dr., Farmington, MO 63640 Call ~32.78 miles northwest of 63781
  • Mid-scale Highway hotel
  • Free breakfast available
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Crown Pointe Lodge, BW Signature Collection in Farmington 4245 Hunt Rd., Farmington, MO 63640 Call ~33.75 miles northwest of 63781
  • 3-star Golf Course property
  • Hotel has 17 suites
From$61
Very Good 4.0 /5 Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale 128 East Walnut St., Murphysboro, IL 62966 Call ~35.80 miles east of 63781
  • Low Cost property
  • 39 sleeping rooms in hotel
Hotel 7 Inn Anna - Anna 100 Richview Dr., Anna, IL 62906 Call ~38.74 miles east of 63781
  • Low Cost hotel
From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
University Inn of Carbondale 2400 West Main St., Carbondale, IL 62901 Call ~39.34 miles east of 63781
  • 3 star property
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Home2 Suites by Hilton Carbondale 200 West Elm St., Carbondale, IL 62901 Call ~40.74 miles east of 63781
  • Three Star Downtown hotel
  • Check-in time: 3:00 pm
From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Train Inn - Carbondale 406 East Stoker St., Carbondale, IL 62901 Call ~40.99 miles east of 63781
  • 3-star Suburban hotel
  • Hotel has 2 suites
From$50
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Carbondale Value Inn & Suites in Carbondale 700 East Main St., Carbondale, IL 62901 Call ~41.37 miles east of 63781
  • Low priced Downtown property
  • Hotel has 2 floors
From$54
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Super 8 by Wyndham Carbondale - Carbondale 1180 East Main St., Carbondale, IL 62901 Call ~41.98 miles east of 63781
  • Inexpensive property
  • Hotel has 63 rooms
From$58
Average 3.0 /5 Reviews Call BookMore Details
Motel 6 Bonne Terre Mo 1017 Highway K, Bonne Terre, MO 63628 Call ~42.04 miles northwest of 63781
  • Low priced hotel
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Bonne Terre in Bonne Terre 8 Northwood Dr., Bonne Terre, MO 63628 Call ~42.16 miles northwest of 63781
  • Economical hotel
From$60
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Best Western Saluki Inn : 801 North Giant City Rd. 801 North Giant City Rd., Carbondale, IL 62902 Call ~42.59 miles east of 63781
  • Midscale Downtown hotel
  • 3 floors in property
From$79
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express Hotel & Suites Sparta by IHG in Sparta 1301 North Market St., Sparta, IL 62286 Call ~42.60 miles north of 63781
  • Midscale Rural hotel
  • Hotel has 3 floors
From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Quality Inn Carbondale University Area - Carbondale 1415 East Main St., Carbondale, IL 62901 Call ~42.65 miles east of 63781
  • Three Star Suburban hotel
  • Comp. Breakfast
Hampton Inn Carbondale : 2175 Reed Station Pkwy. 2175 Reed Station Pkwy., Carbondale, IL 62901 Call ~43.72 miles east of 63781
  • Mid-scale Rural hotel
  • Check in: 3:00pm
From$80
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Carbondale Conference Center An Ihg Hotel - Carbondale 2300 Reed Station Pkwy., Carbondale, IL 62901 Call ~43.94 miles east of 63781
  • 3 star Rural hotel
  • Fitness center on property
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Comfort Inn & Suites Carbondale University Area : 2400 Reed Station Pkwy. 2400 Reed Station Pkwy., Carbondale, IL 62901 Call ~44.08 miles east of 63781
  • 3-star Suburban property
  • Hotel has 3 floors
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
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