63781 Hotels/Accommodations

Super 8 by Wyndham Perryville in Perryville 1119 Vincent Dr., Perryville, MO 63775 Call ~11.20 miles north of 63781
  • Low priced Highway property
  • Hotel has 2 meeting rooms
From$59
Very good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Perryville 1500 Liberty St., Perryville, MO 63775 Call ~11.27 miles north of 63781
  • Low Cost Highway hotel
  • Free breakfast
From$60
Average 3.5 /5 Reviews Call BookMore Details
Drury Inn & Suites Jackson Missouri 225 Drury Lane, Jackson, MO 63755 Call ~17.63 miles east of 63781
  • Three Star Suburban property
  • Hotel has 4 floors
From$79
Very good 4.5 /5 Reviews Call BookMore Details
Comfort Suites in Jackson 2904 Old Orchard Rd., Jackson, MO 63755 Call ~21.91 miles southeast of 63781
  • Midscale Highway property
  • 64 rooms in property
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau : 3003 South Old Orchard Rd. 3003 South Old Orchard Rd., Jackson, MO 63755 Call ~21.92 miles southeast of 63781
  • Affordable Highway hotel
  • Fitness / Gym is on-site
From$85
Very good 4.0 /5 Hotel Reviews Call BookMore Details
TRU by Hilton Cape Girardeau 2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 Call ~22.66 miles southeast of 63781
  • 3-star Highway hotel
  • Free breakfast available
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Arrowrock Inn in Ste Genevieve 17030 New Bremen Rd., Ste Genevieve, MO 63670 Call ~23.37 miles north of 63781
  • Cheap Rural property
  • 2 floors in hotel
From$49
Very good 4.0 /5 Recent Reviews Call BookMore Details
Quality Inn Cape Girardeau North : 2011 North Kingshighway St. 2011 North Kingshighway St., Cape Girardeau, MO 63701 Call ~23.93 miles southeast of 63781
  • Cheap property
  • Hotel has 2 suites
From$60
Very good 4.0 /5 Recent Reviews Call BookMore Details
Drury Lodge 104 South Vantage Dr., Cape Girardeau, MO 63701 Call ~25.35 miles southeast of 63781
  • Three Star Highway hotel
  • Fitness + Health Center
From$80
Average 3.0 /5 Reviews Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau 3351 Percy Dr., Cape Girardeau, MO 63701 Call ~25.35 miles southeast of 63781
  • Mid-scale hotel
  • 8 floors in hotel
From$9999999
Average 3.0 /5 Read Reviews Call BookMore Details
Drury Suites Cape Girardeau in Cape Girardeau 3303 Campster Dr., Cape Girardeau, MO 63701 Call ~25.45 miles southeast of 63781
  • Midscale Highway property
  • Hotel has an eco-friendly policy Read more
From$85
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West : 103 Cape West Pkwy. 103 Cape West Pkwy., Cape Girardeau, MO 63701 Call ~25.54 miles southeast of 63781
  • Cheap hotel
  • Complimentary breakfast is offered
From$9999999
Average 3.0 /5 Reviews Call BookMore Details
Fairfield Inn & Suites Cape Girardeau - Cape Girardeay 433 Cape West Crossing, Cape Girardeay, MO 63703 Call ~25.58 miles southeast of 63781
  • Mid-scale property
  • Check in: 3:00PM
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center 3248 William St., Cape Girardeau, MO 63701 Call ~25.64 miles southeast of 63781
  • Economy Highway property
  • Hotel has 3 floors
From$66
Very good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 by Ihg in Cape Girardeau 3253 William St., Cape Girardeau, MO 63701 Call ~25.67 miles southeast of 63781
  • Three Star property
  • Hotel has 102 suites
From$80
Very good 4.5 /5 Review Score Call BookMore Details
Auburn Place Hotel & Suites in Cape Girardeau 3265 Williams St., Cape Girardeau, MO 63702 Call ~25.75 miles southeast of 63781
  • 3 star Highway hotel
  • 133 sleeping rooms in hotel
From$58
Very good 4.5 /5 Guest Reviews Call BookMore Details
Victorian Inn & Suites : 3256 William St. 3256 William St., Cape Girardeau, MO 63703 Call ~25.76 miles southeast of 63781
  • Affordable Golf Course property
  • 2 floors in property
From$79
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East : 207 South Mount Auburn Rd. 207 South Mount Auburn Rd., Cape Girardeau, MO 63703 Call ~25.76 miles southeast of 63781
  • 3-star Highway hotel
  • Hotel has 86 rooms
From$80
Excellent 5.0 /5 Review Score Call BookMore Details
Candlewood Suites Cape Girardeau by IHG - Cape Girardeau 485 South Mount Auburn Rd., Cape Girardeau, MO 65703 Call ~26.41 miles southeast of 63781
  • Economical Highway property
  • Hotel has 85 suites
From$69
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Chester Il 2150 State St., Chester, IL 62233 Call ~26.70 miles north of 63781
  • 3-star Rural hotel
  • Check-in: 1:00 PM
From$69
Very good 4.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown : 400 Broadway St. 400 Broadway St., Cape Girardeau, MO 63701 Call ~27.74 miles southeast of 63781
  • 3-star Downtown property
  • Hotel has 78 rooms
From$80
Very good 4.0 /5 Review Score Call BookMore Details
Microtel Inn & Suites by Wyndham Sainte Genevieve : 21958 State Highway 32 21958 State Highway 32, Ste. Genevieve, MO 63670 Call ~29.79 miles north of 63781
  • Two star Highway hotel
  • 2 floors in hotel
From$50
Average 3.0 /5 Recent Reviews Call BookMore Details
Baymont Inn and Suites by Wyndham Farmington, MO - Farmington 1625 West Columbia St., Farmington, MO 63640 Call ~32.20 miles west of 63781
  • Affordable Highway hotel
  • Free breakfast
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn Farmington in Farmington 1400 West Liberty St., Farmington, MO 63640 Call ~32.47 miles west of 63781
  • Affordable Rural hotel
  • Check in time: 11:00
From$80
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Farmington by IHG 820 Market St., Farmington, MO 63640 Call ~32.61 miles northwest of 63781
  • Affordable Rural property
  • 60 rooms in property
From$99
Very good 4.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Farmington 930 Valley Creek Dr., Farmington, MO 63640 Call ~32.71 miles northwest of 63781
  • Low Cost property
  • Check in: 3:00 pm
From$49
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Farmington 850 Valley Creek Dr., Farmington, MO 63640 Call ~32.78 miles northwest of 63781
  • 3-star Highway hotel
  • Fitness + Health Center
From$80
Average 3.0 /5 Review Score Call BookMore Details
Crown Pointe Lodge, BW Signature Collection - Farmington 4245 Hunt Rd., Farmington, MO 63640 Call ~33.75 miles northwest of 63781
  • Midscale Golf Course property
  • 3 floors in hotel
From$64
Very good 4.0 /5 Read Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale 128 East Walnut St., Murphysboro, IL 62966 Call ~35.80 miles east of 63781
  • 2-star hotel
  • 39 rooms in hotel
Hotel 7 Inn Anna 100 Richview Dr., Anna, IL 62906 Call ~38.74 miles east of 63781
  • Low priced hotel
From$60
Very good 4.0 /5 Review Score Call BookMore Details
University Inn of Carbondale 2400 West Main St., Carbondale, IL 62901 Call ~39.34 miles east of 63781
  • Three Star property
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Home2 Suites by Hilton Carbondale : 200 West Elm St. 200 West Elm St., Carbondale, IL 62901 Call ~40.74 miles east of 63781
  • Affordable Downtown hotel
  • Hotel has 99 suites
From$99
Very good 4.0 /5 Read Reviews Call BookMore Details
Train Inn 406 East Stoker St., Carbondale, IL 62901 Call ~40.99 miles east of 63781
  • Midscale Suburban hotel
  • 7 rooms in property
From$50
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Carbondale Value Inn & Suites 700 East Main St., Carbondale, IL 62901 Call ~41.37 miles east of 63781
  • Low priced Downtown property
  • Free complimentary breakfast
From$54
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Carbondale 1180 East Main St., Carbondale, IL 62901 Call ~41.98 miles east of 63781
  • Low-priced property
  • Hotel has 2 suites
From$58
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Bonne Terre Mo 1017 Highway K, Bonne Terre, MO 63628 Call ~42.04 miles northwest of 63781
  • Low-priced property
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Bonne Terre : 8 Northwood Dr. 8 Northwood Dr., Bonne Terre, MO 63628 Call ~42.16 miles northwest of 63781
  • Economical hotel
  • Check-in time: 11:00 AM
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Best Western Saluki Inn - Carbondale 801 North Giant City Rd., Carbondale, IL 62902 Call ~42.59 miles east of 63781
  • Mid-scale Downtown hotel
  • Check in: 3:00pm
From$79
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Sparta by IHG 1301 North Market St., Sparta, IL 62286 Call ~42.60 miles north of 63781
  • Midscale Rural property
  • Check in time: 3:00pm
From$99
Very good 4.0 /5 Reviews Call BookMore Details
Quality Inn Carbondale University Area in Carbondale 1415 East Main St., Carbondale, IL 62901 Call ~42.65 miles east of 63781
  • Midscale Suburban hotel
  • Hotel has 64 rooms
Hampton Inn Carbondale 2175 Reed Station Pkwy., Carbondale, IL 62901 Call ~43.72 miles east of 63781
  • 3-star Rural hotel
  • Access to gym on-site
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites University Area An Ihg Hotel in Carbondale 2300 Reed Station Pkwy., Carbondale, IL 62901 Call ~43.94 miles east of 63781
  • Mid-scale Rural property
  • Fitness center on property
From$99
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn & Suites Carbondale University Area 2400 Reed Station Pkwy., Carbondale, IL 62901 Website Call ~44.08 miles east of 63781
  • Three Star Suburban property
  • Hotel has 24 suites
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
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