Hotels in 78221 - San Antonio TX

Only hotels in 78221 zip code are listed below. Search for cheap and discount hotel rates in San Antonio, TX for your upcoming leisure or conference / group travel. We list the best 78221 hotels and motels so you can review the San Antonio hotel list below to find the perfect lodging. Hotels in Bexar county and area code 210 are also listed.


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78221 Hotels/Motels & Accommodations

Photo of Value Place San Antonio Tx (South) Value Place San Antonio Tx (South)
+1-800-230-4134Check Rates
7958 South Ih 35, San Antonio, TX 78224
  • 2 star Highway hotel
  • Hotel has 4 floors
~5.58 Miles from 78221
Photo of La Quinta Inn South Park #0510 La Quinta Inn South Park #0510 - San Antonio
+1-800-997-5148Check Rates
7202 South Pan Am Expressway, San Antonio, TX 78224
  • 3.0/5, Average Read Reviews
  • 3-star Highway property
  • Free breakfast available
~5.93 Miles from 78221
Holiday Inn Express & Suites San Antonio Se Milita : 8222 City Base Lndg
+1-800-997-5149Check Rates
8222 City Base Lndg, San Antonio, TX 78235
  • 3 star Highway hotel
  • 4 floors in hotel
~7.27 Miles from 78221
Exterior of La Quinta Inn La Quinta Inn
+1-800-230-4134Check Rates
3180 Goliad Rd., San Antonio, TX 78223
  • 3.5/5, Average Guest Reviews
  • Cheap Suburban property
  • 2 floors in property
~7.55 Miles from 78221
Holiday Inn Express South
+1-800-997-5148Check Rates
606 Division Ave., San Antonio, TX 78214
  • 4.0/5, Very Good Reviews
  • Affordable hotel
~7.59 Miles from 78221
Image of Elmendorf Lodge Elmendorf Lodge in San Antonio
+1-800-997-5149Check Rates
4900 Via La Circula, San Antonio, TX 78223
  • Midscale Rural property
  • 24 rooms in property
~7.74 Miles from 78221
Photo of Motel 6 Motel 6
+1-800-230-4134Check Rates
748 Hot Wells Blvd., San Antonio, TX 78223
  • Inexpensive Downtown property
  • Check in time: 2:00 PM
~7.76 Miles from 78221
Photo of Super 8 San Antonio Near Alamodome Super 8 San Antonio Near Alamodome in San Antonio
+1-800-997-5148Check Rates
723 Hotwells Blvd., San Antonio, TX 78223
  • Low Cost Downtown hotel
  • 3 floors in property
~7.78 Miles from 78221
Roosevelt Inn Motel in San Antonio
+1-800-997-5149Check Rates
2122 Roosevelt Ave., San Antonio, TX 78210
  • Economical Highway property
  • 2 floors in property
~8.01 Miles from 78221
Matador Motel : 3800 South Zarzamora
+1-800-230-4134Check Rates
3800 South Zarzamora, San Antonio, TX 78225
  • 4.5/5, Very Good Review Score
  • Two-star Suburban property
  • Hotel has 26 rooms
~8.20 Miles from 78221
Days Inn Downtown Riverwalk Area
+1-800-997-5148Check Rates
1500 I 35 South Exit 154b Laredo St., San Antonio, TX 78204
  • 1.5/5, Terrible Guest Reviews
  • Inexpensive Downtown property
  • Check-in: 3:00 P.M.
~9.79 Miles from 78221
Ramada Limited : 1122 South Laredo St.
+1-800-997-5149Check Rates
1122 South Laredo St., San Antonio, TX 78204
  • 2.5/5, Poor Latest Reviews
  • 2 star Downtown hotel
  • Check-in time: 3:00 pm
~10.06 Miles from 78221
Gardenia Inn in San Antonio
+1-800-230-4134Check Rates
307 Beauregard St., San Antonio, TX 78204
  • 5.0/5, Excellent Hotel Reviews
  • Three Star Downtown hotel
  • Hotel has 6 rooms
~10.11 Miles from 78221
Candlewood Suites in San Antonio
+1-800-997-5148Check Rates
1024 South Laredo St., San Antonio, TX 78204
  • 4.0/5, Very Good Review Score
  • 2 star Downtown hotel
  • Fitness center on property
~10.11 Miles from 78221
Super 8 in San Antonio
+1-800-997-5149Check Rates
302 Roland Ave., San Antonio, TX 78210
  • 4.0/5, Very Good Review Score
  • Inexpensive Downtown property
  • Check in: 2:00pm
~10.13 Miles from 78221
Manguson Hotel - San Antonio
+1-800-230-4134Check Rates
1025 South Frio St., San Antonio, TX 78207
  • 1.5/5, Terrible Review Score
  • Economy Downtown hotel
  • Check in: 02:00 PM
~10.14 Miles from 78221
Best Western Alamo Suites : 1002 South Laredo St.
+1-800-997-5148Check Rates
1002 South Laredo St., San Antonio, TX 78204
  • 4.0/5, Very Good Review Score
  • Affordable Downtown hotel
  • 72 suites in hotel
~10.14 Miles from 78221
Holiday Inn Express Market Area San Antonio - San Antonio
+1-800-997-5149Check Rates
102 El Paso St., San Antonio, TX 78204
  • Three Star Downtown hotel
  • Hotel has 78 meeting rooms
~10.27 Miles from 78221
Fairfield Inn & Suites Downtown Market Square in San Antonio
+1-800-230-4134Check Rates
620 South Santa Rosa, San Antonio, TX 78204
  • 4.0/5, Very Good Hotel Reviews
  • 2 star Downtown hotel
  • 110 sleeping rooms in hotel
~10.40 Miles from 78221
Residence Inn by Marriott Downtown Market Square : 628 South Santa Rosa
+1-800-997-5148Check Rates
628 South Santa Rosa, San Antonio, TX 78204
  • 4.0/5, Very Good Hotel Reviews
  • 3 star Downtown property
  • Free breakfast
~10.42 Miles from 78221
Marriott Plaza San Antonio
+1-800-997-5149Check Rates
555 South Alamo, San Antonio, TX 78205
  • 4.0/5, Very Good Reviews
  • Four-star Downtown hotel
  • Hotel has 5 suites
~10.44 Miles from 78221
Courtyard Downtown Market Square
+1-800-230-4134Check Rates
600 South Santa Rosa, San Antonio, TX 78204
  • 4.0/5, Very Good Read Reviews
  • Affordable Downtown hotel
  • 2 meeting rooms in property
~10.44 Miles from 78221
La Quinta Inn & Suites Downtown in San Antonio
+1-800-997-5148Check Rates
100 West Durango St., San Antonio, TX 78204
  • 4.0/5, Very Good Read Reviews
  • Three Star Downtown property
  • Hotel has 6 floors
~10.45 Miles from 78221
Hyatt Place San Antonio Riverwalk
+1-800-997-5149Check Rates
601 South St. Mary's St., San Antonio, TX 78205
  • Affordable Downtown hotel
  • 131 suites in property
~10.45 Miles from 78221
Hampton Inn & Suites Downtown / Market Square - San Antonio
+1-800-230-4134Check Rates
411 South Flores St., San Antonio, TX 78205
  • Three Star Downtown hotel
  • Free breakfast
~10.48 Miles from 78221
Inn on the Riverwalk in San Antonio
+1-800-997-5148Check Rates
129 Woodward Place, San Antonio, TX 78204
  • 4.0/5, Very Good Hotel Reviews
  • Mid-scale Downtown hotel
  • Hotel has 14 rooms
~10.49 Miles from 78221
Holiday Inn San Antonio Downtown Market Square : 318 West Cesar Chavez Blvd.
+1-800-997-5149Check Rates
318 West Cesar Chavez Blvd., San Antonio, TX 78204
  • 3.5/5, Average Reviews
  • Affordable Downtown property
  • 4 floors in hotel
~10.51 Miles from 78221
Holiday Inn San Antonio Downtown Market Square
+1-800-230-4134Check Rates
318 West Durango Blvd., San Antonio, TX 78204
  • 3 star Downtown hotel
  • 6 meeting rooms in hotel
~10.51 Miles from 78221
La Cascada : 226 Dwyer Ave.
+1-800-997-5148Check Rates
226 Dwyer Ave., San Antonio, TX 78204
  • 3 star Downtown property
  • 97 suites in hotel
~10.54 Miles from 78221
The Fairmount Hotel : 401 South Alamo
+1-800-997-5149Check Rates
401 South Alamo, San Antonio, TX 78205
  • 3.0/5, Average Hotel Reviews
  • 3 star Downtown hotel
  • Check in: 3:00PM
~10.56 Miles from 78221
Doubletree by Hilton San Antonio Downtown
+1-800-230-4134Check Rates
502 West Cesar East Chavez Blvd., San Antonio, TX 78207
  • 3.5/5, Average Recent Reviews
  • Midscale Downtown hotel
  • 22 suites in property
~10.56 Miles from 78221
O'brien Hotel An Ascend Collection Hotel
+1-800-997-5148Check Rates
116 Navarro St., San Antonio, TX 78205
  • 4.0/5, Very Good Guest Reviews
  • Mid-scale Downtown property
  • Hotel has 39 rooms
~10.60 Miles from 78221
Carefree Inn
+1-800-997-5149Check Rates
100 Valley Hi Dr., San Antonio, TX 78227
  • 2.0/5, Poor Guest Reviews
  • Low Cost Suburban property
  • Free breakfast available
~10.63 Miles from 78221
Staybridge Suites Downtown Sunset Station in San Antonio
+1-800-230-4134Check Rates
123 Hoefgen Ave., San Antonio, TX 78205
  • Mid-scale Downtown hotel
  • 138 suites in property
~10.66 Miles from 78221
Riverwalk Plaza Hotel & Suites
+1-800-997-5148Check Rates
100 Villita St., San Antonio, TX 78205
  • 3.5/5, Average Guest Reviews
  • Three Star Downtown property
  • 8 suites in property
~10.67 Miles from 78221
Hilton Palacio Del Rio - San Antonio
+1-800-997-5149Check Rates
200 South Alamo St., San Antonio, TX 78205
  • 4.0/5, Very Good Reviews
  • Four star Downtown property
  • 31 meeting rooms in hotel
~10.68 Miles from 78221
La Hacienda Inn Alamodome / Riverwalk : 1524 East Commerce St.
+1-800-230-4134Check Rates
1524 East Commerce St., San Antonio, TX 78205
  • Economy Convention Center hotel
  • Check-in: 3:00 pm
~10.70 Miles from 78221
Grand Hyatt San Antonio - San Antonio
+1-800-997-5148Check Rates
600 East Market St., San Antonio, TX 78205
  • 4.0/5, Very Good Reviews
  • 4 star Downtown hotel
  • 62 suites in property
~10.70 Miles from 78221
Cityview Inn & Suites Sunset Station - San Antonio
+1-800-997-5149Check Rates
1306 East Commerce, San Antonio, TX 78205
  • 4.0/5, Very Good Latest Reviews
  • Economical Downtown property
  • Hotel has 3 floors
~10.72 Miles from 78221
Hotel Contessa Riverwalk Luxury Suites : 306 West Market St.
+1-800-230-4134Check Rates
306 West Market St., San Antonio, TX 78205
  • 4.5/5, Very Good Review Score
  • High-end Downtown hotel
  • 265 sleeping rooms in hotel
~10.72 Miles from 78221
La Quinta Market Square
+1-800-997-5148Check Rates
900 Dolorosa, San Antonio, TX 78207 ~10.73 Miles from 78221
Homewood Suites by Hilton Riverwalk : 432 West Market St.
+1-800-997-5149Check Rates
432 West Market St., San Antonio, TX 78205
  • 4.0/5, Very Good Read Reviews
  • Midscale Downtown hotel
  • Gym is available on property
~10.73 Miles from 78221
Best Western Plus Sunset Suites Riverwalk
+1-800-230-4134Check Rates
1103 East Commerce, San Antonio, TX 78205
  • 4.5/5, Very Good Recent Reviews
  • Affordable Downtown property
  • 4 floors in hotel
~10.74 Miles from 78221
Westin Riverwalk - San Antonio
+1-800-997-5148Check Rates
420 West Market, San Antonio, TX 78205
  • 4-star Downtown hotel
  • Check in time: 3:00pm
~10.74 Miles from 78221
The Westin Riverwalk
+1-800-997-5149Check Rates
420 West Market St., San Antonio, TX 78205
  • 4.5/5, Very Good Review Score
  • High end Downtown property
  • Hotel has 15 floors
~10.74 Miles from 78221
Motel 6 Market Square in San Antonio
+1-800-230-4134Check Rates
211 North Pecos St., San Antonio, TX 78207
  • 2-star hotel
  • 2 floors in hotel
~10.74 Miles from 78221
Holiday Inn Express Suites Rivercenter - San Antonio
+1-800-997-5148Check Rates
1309 East Commerce St., San Antonio, TX 78205
  • 4.0/5, Very Good Guest Reviews
  • Three Star Downtown property
  • Hotel has 60 suites
~10.75 Miles from 78221
Drury Plaza River Walk San Antonio in San Antonio
+1-800-997-5149Check Rates
105 South St. Mary's St., San Antonio, TX 78205
  • 3-star Downtown property
  • Gym is available on property
~10.76 Miles from 78221
San Antonio Marriott Rivercenter & Riverwalk Hotel in San Antonio
+1-800-230-4134Check Rates
101 Bowie St., San Antonio, TX 78205
  • 4 star Downtown hotel
  • 38 floors in property
~10.78 Miles from 78221
Exterior of Drury Plaza Hotel San Antonio Riverwalk Drury Plaza Hotel San Antonio Riverwalk : 105 South Saint Marys St.
+1-800-997-5148Check Rates
105 South Saint Marys St., San Antonio, TX 78205
  • 4.5/5, Very Good Recent Reviews
  • Midscale Downtown property
  • Fitness / Gym is on-site
~10.79 Miles from 78221



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