Hotels in 78221 - San Antonio TX

Only hotels in 78221 zip code are listed below. Search for cheap and discount hotel rates in San Antonio, TX for your upcoming leisure or conference / group travel. We list the best 78221 hotels and motels so you can review the San Antonio hotel list below to find the perfect lodging. Hotels in Bexar county and area code 210 are also listed.


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78221 Hotels/Motels & Accommodations

Image of Value Place San Antonio Tx (South)Value Place San Antonio Tx (South) : 7958 South Ih 35
+1-800-230-4134Check Rates
7958 South Ih 35, San Antonio, TX 78224
  • Economy Highway hotel
  • Check in time: 3:00 PM
~5.58 Miles from 78221
Photo of La Quinta Inn South Park #0510La Quinta Inn South Park #0510
+1-800-997-5148Check Rates
7202 South Pan Am Expressway, San Antonio, TX 78224
  • 3.0/5, Average Review Score
  • Mid-scale Highway hotel
  • Hotel has 2 floors
~5.93 Miles from 78221
Holiday Inn Express & Suites San Antonio Se Milita
+1-800-997-5149Check Rates
8222 City Base Lndg, San Antonio, TX 78235
  • 3-star Highway hotel
  • Hotel has 4 floors
~7.27 Miles from 78221
Image of La Quinta InnLa Quinta Inn
+1-800-230-4134Check Rates
3180 Goliad Rd., San Antonio, TX 78223
  • 3.5/5, Average Reviews
  • Low priced Suburban hotel
  • Check-in: 2:00 am
~7.55 Miles from 78221
Holiday Inn Express South : 606 Division Ave.
+1-800-997-5148Check Rates
606 Division Ave., San Antonio, TX 78214~7.59 Miles from 78221
Photo of Elmendorf LodgeElmendorf Lodge in San Antonio
+1-800-997-5149Check Rates
4900 Via La Circula, San Antonio, TX 78223
  • Three Star Rural hotel
  • 24 sleeping rooms in hotel
~7.74 Miles from 78221
Image of Motel 6Motel 6
+1-800-230-4134Check Rates
748 Hot Wells Blvd., San Antonio, TX 78223
  • Cheap Downtown hotel
  • Hotel has 74 rooms
~7.76 Miles from 78221
Exterior of Super 8 San Antonio Near AlamodomeSuper 8 San Antonio Near Alamodome - San Antonio
+1-800-997-5148Check Rates
723 Hotwells Blvd., San Antonio, TX 78223
  • Inexpensive Downtown hotel
  • Complimentary breakfast is offered
~7.78 Miles from 78221
Roosevelt Inn Motel - San Antonio
+1-800-997-5149Check Rates
2122 Roosevelt Ave., San Antonio, TX 78210
  • Low priced Highway hotel
  • 10 suites in hotel
~8.01 Miles from 78221
Matador Motel - San Antonio
+1-800-230-4134Check Rates
3800 South Zarzamora, San Antonio, TX 78225
  • 4.5/5, Very Good Hotel Reviews
  • Two star Suburban property
  • 26 rooms in property
~8.20 Miles from 78221
Days Inn Downtown Riverwalk Area in San Antonio
+1-800-997-5148Check Rates
1500 I 35 South Exit 154b Laredo St., San Antonio, TX 78204
  • 1.5/5, Terrible Reviews
  • Cheap Downtown hotel
  • 90 rooms in property
~9.79 Miles from 78221
Ramada Limited - San Antonio
+1-800-997-5149Check Rates
1122 South Laredo St., San Antonio, TX 78204
  • 2.5/5, Poor Review Score
  • Low-priced Downtown hotel
  • Fitness center on property
~10.06 Miles from 78221
Gardenia Inn : 307 Beauregard St.
+1-800-230-4134Check Rates
307 Beauregard St., San Antonio, TX 78204
  • 5.0/5, Excellent Guest Reviews
  • Midscale Downtown property
  • Hotel has 3 floors
~10.11 Miles from 78221
Candlewood Suites - San Antonio
+1-800-997-5148Check Rates
1024 South Laredo St., San Antonio, TX 78204
  • 4.0/5, Very Good Review Score
  • Cheap Downtown hotel
  • Check-in: 3:00 pm
~10.11 Miles from 78221
Super 8 - San Antonio
+1-800-997-5149Check Rates
302 Roland Ave., San Antonio, TX 78210
  • 4.0/5, Very Good Review Score
  • Low-priced Downtown property
  • 2 floors in property
~10.13 Miles from 78221
Manguson Hotel
+1-800-230-4134Check Rates
1025 South Frio St., San Antonio, TX 78207
  • 1.5/5, Terrible Reviews
  • Cheap Downtown property
  • Hotel has 3 floors
~10.14 Miles from 78221
Best Western Alamo Suites - San Antonio
+1-800-997-5148Check Rates
1002 South Laredo St., San Antonio, TX 78204
  • 4.0/5, Very Good Latest Reviews
  • 3 star Downtown hotel
  • Hotel has 72 suites
~10.14 Miles from 78221
Holiday Inn Express Market Area San Antonio
+1-800-997-5149Check Rates
102 El Paso St., San Antonio, TX 78204
  • Midscale Downtown property
  • Hotel has 78 suites
~10.27 Miles from 78221
Fairfield Inn & Suites Downtown Market Square
+1-800-230-4134Check Rates
620 South Santa Rosa, San Antonio, TX 78204
  • 4.0/5, Very Good Latest Reviews
  • Inexpensive Downtown hotel
  • Free breakfast
~10.40 Miles from 78221
Residence Inn by Marriott Downtown Market Square : 628 South Santa Rosa
+1-800-997-5148Check Rates
628 South Santa Rosa, San Antonio, TX 78204
  • 4.0/5, Very Good Read Reviews
  • Midscale Downtown property
  • 95 suites in property
~10.42 Miles from 78221
Marriott Plaza San Antonio in San Antonio
+1-800-997-5149Check Rates
555 South Alamo, San Antonio, TX 78205
  • 4.0/5, Very Good Read Reviews
  • Four star Downtown property
  • 15 meeting rooms in property
~10.44 Miles from 78221
Courtyard Downtown Market Square : 600 South Santa Rosa
+1-800-230-4134Check Rates
600 South Santa Rosa, San Antonio, TX 78204
  • 4.0/5, Very Good Reviews
  • Midscale Downtown hotel
  • 3 floors in property
~10.44 Miles from 78221
La Quinta Inn & Suites Downtown
+1-800-997-5148Check Rates
100 West Durango St., San Antonio, TX 78204
  • 4.0/5, Very Good Recent Reviews
  • 3 star Downtown hotel
  • 6 floors in property
~10.45 Miles from 78221
Hyatt Place San Antonio Riverwalk : 601 South St. Mary's St.
+1-800-997-5149Check Rates
601 South St. Mary's St., San Antonio, TX 78205
  • Affordable Downtown property
  • Check in time: 3:00PM
~10.45 Miles from 78221
Hampton Inn & Suites Downtown / Market Square : 411 South Flores St.
+1-800-230-4134Check Rates
411 South Flores St., San Antonio, TX 78205
  • Mid-scale Downtown property
  • Free comp. breakfast
~10.48 Miles from 78221
Inn on the Riverwalk
+1-800-997-5148Check Rates
129 Woodward Place, San Antonio, TX 78204
  • 4.0/5, Very Good Recent Reviews
  • Affordable Downtown property
  • 3 suites in property
~10.49 Miles from 78221
Holiday Inn San Antonio Downtown Market Square
+1-800-997-5149Check Rates
318 West Cesar Chavez Blvd., San Antonio, TX 78204
  • 3.5/5, Average Reviews
  • Affordable Downtown property
  • 4 floors in hotel
~10.51 Miles from 78221
Holiday Inn San Antonio Downtown Market Square
+1-800-230-4134Check Rates
318 West Durango Blvd., San Antonio, TX 78204
  • Mid-scale Downtown property
  • 2 suites in property
~10.51 Miles from 78221
La Cascada : 226 Dwyer Ave.
+1-800-997-5148Check Rates
226 Dwyer Ave., San Antonio, TX 78204
  • Three Star Downtown hotel
  • 97 suites in property
~10.54 Miles from 78221
The Fairmount Hotel - San Antonio
+1-800-997-5149Check Rates
401 South Alamo, San Antonio, TX 78205
  • 3.0/5, Average Recent Reviews
  • 3-star Downtown property
  • 14 suites in hotel
~10.56 Miles from 78221
O'brien Hotel An Ascend Collection Hotel - San Antonio
+1-800-230-4134Check Rates
116 Navarro St., San Antonio, TX 78205
  • 4.0/5, Very Good Review Score
  • Mid-scale Downtown hotel
  • Free comp. breakfast
~10.60 Miles from 78221
Stay Express Inn & Suites in San Antonio
+1-800-997-5148Check Rates
100 Valley Hi Dr., San Antonio, TX 78227~10.63 Miles from 78221
Staybridge Suites Downtown Sunset Station
+1-800-997-5149Check Rates
123 Hoefgen Ave., San Antonio, TX 78205
  • Affordable Downtown property
  • 138 sleeping rooms in hotel
~10.66 Miles from 78221
Riverwalk Plaza Hotel & Suites
+1-800-230-4134Check Rates
100 Villita St., San Antonio, TX 78205
  • 3.5/5, Average Read Reviews
  • 3 star Downtown hotel
  • Gym is available on property
~10.67 Miles from 78221
Hilton Palacio Del Rio : 200 South Alamo St.
+1-800-997-5148Check Rates
200 South Alamo St., San Antonio, TX 78205
  • 4.0/5, Very Good Guest Reviews
  • Four star Downtown hotel
  • Check in: 3:00 pm
~10.68 Miles from 78221
La Hacienda Inn Alamodome / Riverwalk
+1-800-997-5149Check Rates
1524 East Commerce St., San Antonio, TX 78205
  • Low-priced Convention Center property
  • 2 floors in hotel
~10.70 Miles from 78221
Grand Hyatt San Antonio in San Antonio
+1-800-230-4134Check Rates
600 East Market St., San Antonio, TX 78205
  • 4.0/5, Very Good Reviews
  • Expensive Downtown hotel
  • 63 conference rooms in property
~10.70 Miles from 78221
Cityview Inn & Suites Sunset Station - San Antonio
+1-800-997-5148Check Rates
1306 East Commerce, San Antonio, TX 78205
  • 4.0/5, Very Good Review Score
  • Inexpensive Downtown hotel
  • 3 floors in property
~10.72 Miles from 78221
Hotel Contessa Riverwalk Luxury Suites : 306 West Market St.
+1-800-997-5149Check Rates
306 West Market St., San Antonio, TX 78205
  • 4.5/5, Very Good Hotel Reviews
  • High-end Downtown hotel
  • 10 conference rooms in property
~10.72 Miles from 78221
La Quinta Market Square - San Antonio
+1-800-230-4134Check Rates
900 Dolorosa, San Antonio, TX 78207~10.73 Miles from 78221
Homewood Suites by Hilton Riverwalk
+1-800-997-5148Check Rates
432 West Market St., San Antonio, TX 78205
  • 4.0/5, Very Good Recent Reviews
  • 3 star Downtown hotel
  • 3 meeting rooms in hotel
~10.73 Miles from 78221
Best Western Plus Sunset Suites Riverwalk - San Antonio
+1-800-997-5149Check Rates
1103 East Commerce, San Antonio, TX 78205
  • 4.5/5, Very Good Hotel Reviews
  • Midscale Downtown hotel
  • Hotel has 4 floors
~10.74 Miles from 78221
Westin Riverwalk
+1-800-230-4134Check Rates
420 West Market, San Antonio, TX 78205
  • High end Downtown property
  • Hotel has 10 meeting rooms
~10.74 Miles from 78221
The Westin Riverwalk : 420 West Market St.
+1-800-997-5148Check Rates
420 West Market St., San Antonio, TX 78205
  • 4.5/5, Very Good Review Score
  • 4 star Downtown hotel
  • Check-in time: 3:00pm
~10.74 Miles from 78221
Motel 6 Market Square in San Antonio
+1-800-997-5149Check Rates
211 North Pecos St., San Antonio, TX 78207
  • Two-star hotel
  • Hotel has 119 rooms
~10.74 Miles from 78221
Holiday Inn Express Suites Rivercenter - San Antonio
+1-800-230-4134Check Rates
1309 East Commerce St., San Antonio, TX 78205
  • 4.0/5, Very Good Review Score
  • Midscale Downtown property
  • Hotel has 4 floors
~10.75 Miles from 78221
Drury Plaza River Walk San Antonio : 105 South St. Mary's St.
+1-800-997-5148Check Rates
105 South St. Mary's St., San Antonio, TX 78205
  • Affordable Downtown property
  • Hotel has 368 rooms
~10.76 Miles from 78221
San Antonio Marriott Rivercenter & Riverwalk Hotel in San Antonio
+1-800-997-5149Check Rates
101 Bowie St., San Antonio, TX 78205
  • Expensive Downtown hotel
  • Fitness center on property
~10.78 Miles from 78221
Exterior of Drury Plaza Hotel San Antonio RiverwalkDrury Plaza Hotel San Antonio Riverwalk in San Antonio
+1-800-230-4134Check Rates
105 South Saint Marys St., San Antonio, TX 78205
  • 4.5/5, Very Good Hotel Reviews
  • Mid-scale Downtown hotel
  • 368 rooms in hotel
~10.79 Miles from 78221
Watermark Hotel & Spa
+1-800-997-5148Check Rates
212 West Crockett St., San Antonio, TX 78205~10.83 Miles from 78221



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