Hotels in 78221 - San Antonio TX

Only hotels in 78221 zip code are listed below. Search for cheap and discount hotel rates in San Antonio, TX for your upcoming leisure or conference / group travel. We list the best 78221 hotels and motels so you can review the San Antonio hotel list below to find the perfect lodging. Hotels in Bexar county and area code 210 are also listed.


Find availability nearby Rooms Check-In Check-Out  
Show Calendar Show Calendar Start My Search >
(select the discounts you qualify for)
Star Rating




Hotel Name

Price Range (USD)
to
Amenities







Set My Filter

78221 Hotels/Motels & Accommodations

Photo of Value Place San Antonio Tx (South)Value Place San Antonio Tx (South)
+1-800-230-4134Check Rates
7958 South Ih 35, San Antonio, TX 78224
  • Cheap Highway property
  • Hotel has 4 floors
~5.58 Miles from 78221
Photo of La Quinta Inn South Park #0510La Quinta Inn South Park #0510
+1-800-997-5148Check Rates
7202 South Pan Am Expressway, San Antonio, TX 78224
  • 2.5/5, Poor Review Score
  • Three Star Highway hotel
  • Check in: 3:00 PM
~5.93 Miles from 78221
Holiday Inn Express & Suites San Antonio Se Milita
+1-800-997-5149Check Rates
8222 City Base Lndg, San Antonio, TX 78235
  • 3 star Highway property
  • Gym / Fitness Center Available
~7.27 Miles from 78221
Image of La Quinta InnLa Quinta Inn
+1-800-230-4134Check Rates
3180 Goliad Rd., San Antonio, TX 78223
  • 3.5/5, Average Guest Reviews
  • Cheap Suburban property
  • Hotel has 115 rooms
~7.55 Miles from 78221
Holiday Inn Express South
+1-800-997-5148Check Rates
606 Division Ave., San Antonio, TX 78214~7.59 Miles from 78221
Exterior of Elmendorf LodgeElmendorf Lodge
+1-800-997-5149Check Rates
4900 Via La Circula, San Antonio, TX 78223
  • 3 star Rural hotel
  • 24 sleeping rooms in hotel
~7.74 Miles from 78221
Exterior of Motel 6Motel 6 in San Antonio
+1-800-230-4134Check Rates
748 Hot Wells Blvd., San Antonio, TX 78223
  • Cheap Downtown hotel
  • Hotel has 74 rooms
~7.76 Miles from 78221
Exterior of Super 8 San Antonio Near AlamodomeSuper 8 San Antonio Near Alamodome in San Antonio
+1-800-997-5148Check Rates
723 Hotwells Blvd., San Antonio, TX 78223
  • Cheap Downtown property
  • Complimentary breakfast is offered
~7.78 Miles from 78221
Roosevelt Inn Motel in San Antonio
+1-800-997-5149Check Rates
2122 Roosevelt Ave., San Antonio, TX 78210
  • Economical Highway hotel
  • Free breakfast available
~8.01 Miles from 78221
Matador Motel - San Antonio
+1-800-230-4134Check Rates
3800 South Zarzamora, San Antonio, TX 78225
  • 4.5/5, Very Good Guest Reviews
  • Low-priced Suburban hotel
  • Hotel has 26 rooms
~8.20 Miles from 78221
Days Inn Downtown Riverwalk Area
+1-800-997-5148Check Rates
1500 I 35 South Exit 154b Laredo St., San Antonio, TX 78204
  • 1.5/5, Terrible Reviews
  • 2-star Downtown property
  • 90 rooms in hotel
~9.79 Miles from 78221
Days Inn Splashtown / Att Center : 3443 Pan Am Expressway
+1-800-997-5149Check Rates
3443 Pan Am Expressway, San Antonio, TX 78219
  • Economy Highway property
  • Hotel has 2 floors
~9.95 Miles from 78221
Ramada Limited - San Antonio
+1-800-230-4134Check Rates
1122 South Laredo St., San Antonio, TX 78204~10.06 Miles from 78221
Gardenia Inn : 307 Beauregard St.
+1-800-997-5148Check Rates
307 Beauregard St., San Antonio, TX 78204
  • 5.0/5, Excellent Reviews
  • Midscale Downtown property
  • Comp. Breakfast
~10.11 Miles from 78221
Candlewood Suites : 1024 South Laredo St.
+1-800-997-5149Check Rates
1024 South Laredo St., San Antonio, TX 78204
  • 4.0/5, Very Good Reviews
  • Two-star Downtown hotel
  • Gym / Fitness Center Available
~10.11 Miles from 78221
Super 8
+1-800-230-4134Check Rates
302 Roland Ave., San Antonio, TX 78210
  • 4.0/5, Very Good Read Reviews
  • 2 star Downtown property
  • Free breakfast
~10.13 Miles from 78221
Manguson Hotel - San Antonio
+1-800-997-5148Check Rates
1025 South Frio St., San Antonio, TX 78207
  • 1.5/5, Terrible Hotel Reviews
  • Inexpensive Downtown hotel
  • 85 sleeping rooms in hotel
~10.14 Miles from 78221
Best Western Alamo Suites - San Antonio
+1-800-997-5149Check Rates
1002 South Laredo St., San Antonio, TX 78204
  • 4.0/5, Very Good Guest Reviews
  • Midscale Downtown hotel
  • Hotel has 72 suites
~10.14 Miles from 78221
Holiday Inn Express Downtown Market Area : 102 El Paso St.
+1-800-230-4134Check Rates
102 El Paso St., San Antonio, TX 78204
  • 3.5/5, Average Review Score
  • Midscale Downtown hotel
  • 78 rooms in property
~10.27 Miles from 78221
Fairfield Inn & Suites Downtown Market Square : 620 South Santa Rosa
+1-800-997-5148Check Rates
620 South Santa Rosa, San Antonio, TX 78204
  • 4.0/5, Very Good Review Score
  • Low priced Downtown hotel
  • 4 floors in hotel
~10.40 Miles from 78221
Residence Inn by Marriott Downtown Market Square in San Antonio
+1-800-997-5149Check Rates
628 South Santa Rosa, San Antonio, TX 78204
  • 4.0/5, Very Good Guest Reviews
  • Affordable Downtown hotel
  • Fitness + Health Center
~10.42 Miles from 78221
Marriott Plaza San Antonio
+1-800-230-4134Check Rates
555 South Alamo, San Antonio, TX 78205
  • 4.0/5, Very Good Guest Reviews
  • Four star Downtown property
  • Hotel has 15 meeting rooms
~10.44 Miles from 78221
Courtyard Downtown Market Square in San Antonio
+1-800-997-5148Check Rates
600 South Santa Rosa, San Antonio, TX 78204
  • 4.0/5, Very Good Latest Reviews
  • Three Star Downtown property
  • Hotel has 2 meeting rooms
~10.44 Miles from 78221
La Quinta Inn & Suites Downtown
+1-800-997-5149Check Rates
100 West Durango St., San Antonio, TX 78204
  • 4.0/5, Very Good Reviews
  • Mid-scale Downtown property
  • Hotel has 6 floors
~10.45 Miles from 78221
Hyatt Place San Antonio Riverwalk
+1-800-230-4134Check Rates
601 South St. Mary's St., San Antonio, TX 78205
  • 3-star Downtown hotel
  • 132 rooms in hotel
~10.45 Miles from 78221
Hampton Inn & Suites Downtown / Market Square in San Antonio
+1-800-997-5148Check Rates
411 South Flores St., San Antonio, TX 78205
  • Three Star Downtown hotel
  • Hotel has 4 floors
~10.48 Miles from 78221
Inn on the Riverwalk : 129 Woodward Place
+1-800-997-5149Check Rates
129 Woodward Place, San Antonio, TX 78204
  • 4.0/5, Very Good Guest Reviews
  • Affordable Downtown property
  • Check-in: 3:00 pm
~10.49 Miles from 78221
Holiday Inn San Antonio Downtown Market Square - San Antonio
+1-800-230-4134Check Rates
318 West Cesar Chavez Blvd., San Antonio, TX 78204
  • 3.5/5, Average Recent Reviews
  • Midscale Downtown hotel
  • Hotel has 8 meeting rooms
~10.51 Miles from 78221
Holiday Inn San Antonio Downtown Market Square
+1-800-997-5148Check Rates
318 West Durango Blvd., San Antonio, TX 78204
  • Mid-scale Downtown hotel
  • 6 meeting rooms in hotel
~10.51 Miles from 78221
La Cascada - San Antonio
+1-800-997-5149Check Rates
226 Dwyer Ave., San Antonio, TX 78204
  • Mid-scale Downtown hotel
  • Hotel has 10 floors
~10.54 Miles from 78221
The Fairmount Hotel in San Antonio
+1-800-230-4134Check Rates
401 South Alamo, San Antonio, TX 78205
  • 3.0/5, Average Recent Reviews
  • Midscale Downtown property
  • 37 rooms in hotel
~10.56 Miles from 78221
Doubletree by Hilton San Antonio Downtown : 502 West Cesar East Chavez Blvd.
+1-800-997-5148Check Rates
502 West Cesar East Chavez Blvd., San Antonio, TX 78207
  • 3.5/5, Average Guest Reviews
  • 3-star Downtown property
  • 11 meeting rooms in hotel
~10.56 Miles from 78221
O'brien Hotel An Ascend Collection Hotel - San Antonio
+1-800-997-5149Check Rates
116 Navarro St., San Antonio, TX 78205
  • 4.0/5, Very Good Review Score
  • 3-star Downtown hotel
  • Fitness center on property
~10.60 Miles from 78221
Carefree Inn
+1-800-230-4134Check Rates
100 Valley Hi Dr., San Antonio, TX 78227
  • 2.0/5, Poor Latest Reviews
  • Two star Suburban property
  • 2 floors in property
~10.63 Miles from 78221
Staybridge Suites Downtown Sunset Station : 123 Hoefgen Ave.
+1-800-997-5148Check Rates
123 Hoefgen Ave., San Antonio, TX 78205
  • Mid-scale Downtown hotel
  • Check-in time: 3:00pm
~10.66 Miles from 78221
Riverwalk Plaza Hotel & Suites : 100 Villita St.
+1-800-997-5149Check Rates
100 Villita St., San Antonio, TX 78205
  • 3.5/5, Average Hotel Reviews
  • Affordable Downtown hotel
  • 7 meeting rooms in hotel
~10.67 Miles from 78221
Hilton Palacio Del Rio in San Antonio
+1-800-230-4134Check Rates
200 South Alamo St., San Antonio, TX 78205
  • 4.0/5, Very Good Review Score
  • Four star Downtown hotel
  • Gym is available on property
~10.68 Miles from 78221
La Hacienda Inn Alamodome / Riverwalk
+1-800-997-5148Check Rates
1524 East Commerce St., San Antonio, TX 78205
  • Economy Convention Center property
  • Free comp. breakfast
~10.70 Miles from 78221
Grand Hyatt San Antonio : 600 East Market St.
+1-800-997-5149Check Rates
600 East Market St., San Antonio, TX 78205
  • 4.0/5, Very Good Guest Reviews
  • 4 star Downtown property
  • 63 meeting rooms in hotel
~10.70 Miles from 78221
Cityview Inn & Suites Sunset Station in San Antonio
+1-800-230-4134Check Rates
1306 East Commerce, San Antonio, TX 78205
  • 4.0/5, Very Good Review Score
  • Cheap Downtown property
  • Check-in time: 1400
~10.72 Miles from 78221
Hotel Contessa Riverwalk Luxury Suites
+1-800-997-5148Check Rates
306 West Market St., San Antonio, TX 78205
  • 4.5/5, Very Good Latest Reviews
  • 4 star Downtown hotel
  • 10 meeting rooms in hotel
~10.72 Miles from 78221
La Quinta Market Square : 900 Dolorosa
+1-800-997-5149Check Rates
900 Dolorosa, San Antonio, TX 78207
  • 4.0/5, Very Good Reviews
  • Mid-scale property
~10.73 Miles from 78221
Homewood Suites by Hilton Riverwalk : 432 West Market St.
+1-800-230-4134Check Rates
432 West Market St., San Antonio, TX 78205
  • 4.0/5, Very Good Guest Reviews
  • Affordable Downtown hotel
  • 3 meeting rooms in property
~10.73 Miles from 78221
Best Western Plus Sunset Suites Riverwalk in San Antonio
+1-800-997-5148Check Rates
1103 East Commerce, San Antonio, TX 78205
  • 4.5/5, Very Good Hotel Reviews
  • Three Star Downtown property
  • 3 meeting rooms in property
~10.74 Miles from 78221
Westin Riverwalk in San Antonio
+1-800-997-5149Check Rates
420 West Market, San Antonio, TX 78205
  • High end Downtown property
  • 15 floors in property
~10.74 Miles from 78221
The Westin Riverwalk in San Antonio
+1-800-230-4134Check Rates
420 West Market St., San Antonio, TX 78205
  • 4.5/5, Very Good Review Score
  • Four star Downtown property
  • Check-in: 3:00pm
~10.74 Miles from 78221
Motel 6 Market Square - San Antonio
+1-800-997-5148Check Rates
211 North Pecos St., San Antonio, TX 78207
  • Two-star hotel
  • 2 floors in property
~10.74 Miles from 78221
Holiday Inn Express Suites Rivercenter - San Antonio
+1-800-997-5149Check Rates
1309 East Commerce St., San Antonio, TX 78205
  • 4.0/5, Very Good Guest Reviews
  • Mid-scale Downtown property
  • Check-in: 4:00 PM
~10.75 Miles from 78221
Drury Plaza River Walk San Antonio : 105 South St. Mary's St.
+1-800-230-4134Check Rates
105 South St. Mary's St., San Antonio, TX 78205
  • 3 star Downtown property
  • Free comp. breakfast
~10.76 Miles from 78221
San Antonio Marriott Rivercenter & Riverwalk Hotel
+1-800-997-5148Check Rates
101 Bowie St., San Antonio, TX 78205
  • Four star Downtown hotel
  • Shuttle to airport available
~10.78 Miles from 78221



Next: Show All Available 78221 Hotels with Pricing >