Hotels in 78221 - San Antonio TX

Only hotels in 78221 zip code are listed below. Search for cheap and discount hotel rates in San Antonio, TX for your upcoming leisure or conference / group travel. We list the best 78221 hotels and motels so you can review the San Antonio hotel list below to find the perfect lodging. Hotels in Bexar county and area code 210 are also listed.


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78221 Hotels/Motels & Accommodations

Image of Value PlaceValue Place
+1-800-230-4134Check Rates
7958 South Ih 35, San Antonio, TX 78224
  • Inexpensive Highway property
  • Hotel has a green policy Learn more
~5.58 Miles from 78221
Photo of La Quinta Inn South Park #0510La Quinta Inn South Park #0510 - San Antonio
+1-800-997-5148Check Rates
7202 South Pan Am Expressway, San Antonio, TX 78224
  • 3.0/5, Average Review Score
  • Three Star Highway hotel
  • 2 floors in hotel
~5.93 Miles from 78221
Holiday Inn Express & Suites San Antonio Se Milita : 8222 City Base Lndg
+1-800-997-5149Check Rates
8222 City Base Lndg, San Antonio, TX 78235
  • 3-star hotel
~7.27 Miles from 78221
Image of La Quinta InnLa Quinta Inn in San Antonio
+1-800-230-4134Check Rates
3180 Goliad Rd., San Antonio, TX 78223
  • 4.0/5, Very Good Review Score
  • Two star Suburban hotel
  • 2 floors in hotel
~7.55 Miles from 78221
Holiday Inn Express South - San Antonio
+1-800-997-5148Check Rates
606 Division Ave., San Antonio, TX 78214~7.59 Miles from 78221
Photo of Elmendorf LodgeElmendorf Lodge
+1-800-997-5149Check Rates
4900 Via La Circula, San Antonio, TX 78223
  • 3 star Rural property
  • Check-in time: 3:00 pm
~7.74 Miles from 78221
Photo of Motel 6Motel 6 - San Antonio
+1-800-230-4134Check Rates
748 Hot Wells Blvd., San Antonio, TX 78223
  • 2 star Downtown property
  • Hotel has 74 rooms
~7.76 Miles from 78221
Image of Super 8 San Antonio Near AlamodomeSuper 8 San Antonio Near Alamodome in San Antonio
+1-800-997-5148Check Rates
723 Hotwells Blvd., San Antonio, TX 78223
  • Low priced Downtown property
  • Fitness / Gym is on-site
~7.78 Miles from 78221
Roosevelt Inn Motel
+1-800-997-5149Check Rates
2122 Roosevelt Ave., San Antonio, TX 78210
  • Economical Highway property
  • Hotel has 10 suites
~8.01 Miles from 78221
Matador Motel - San Antonio
+1-800-230-4134Check Rates
3800 South Zarzamora, San Antonio, TX 78225
  • 4.5/5, Very Good Read Reviews
  • Inexpensive Suburban property
  • Check in: 2:00 PM
~8.20 Miles from 78221
Days Inn Downtown Riverwalk Area - San Antonio
+1-800-997-5148Check Rates
1500 I 35 South Exit 154b Laredo St., San Antonio, TX 78204
  • 1.5/5, Terrible Reviews
  • Economy Downtown hotel
  • Comp. Breakfast
~9.79 Miles from 78221
Days Inn Splashtown / Att Center
+1-800-997-5149Check Rates
3443 Pan Am Expressway, San Antonio, TX 78219
  • Economy Highway hotel
  • Check-in time: 3:00pm
~9.95 Miles from 78221
Ramada Limited - San Antonio
+1-800-230-4134Check Rates
1122 South Laredo St., San Antonio, TX 78204
  • 1.5/5, Terrible Read Reviews
  • 2 star Downtown property
  • 2 floors in hotel
~10.06 Miles from 78221
Gardenia Inn
+1-800-997-5148Check Rates
307 Beauregard St., San Antonio, TX 78204
  • 5.0/5, Excellent Hotel Reviews
  • Affordable Downtown hotel
  • Hotel has 3 floors
~10.11 Miles from 78221
Candlewood Suites : 1024 South Laredo St.
+1-800-997-5149Check Rates
1024 South Laredo St., San Antonio, TX 78204
  • 4.5/5, Very Good Latest Reviews
  • 2-star Downtown hotel
  • Access to gym on-site
~10.11 Miles from 78221
Super 8 - San Antonio
+1-800-230-4134Check Rates
302 Roland Ave., San Antonio, TX 78210
  • 4.0/5, Very Good Guest Reviews
  • Low-priced Downtown property
  • Hotel has 24 suites
~10.13 Miles from 78221
Manguson Hotel
+1-800-997-5148Check Rates
1025 South Frio St., San Antonio, TX 78207
  • 1.5/5, Terrible Hotel Reviews
  • Economical Downtown hotel
  • Free comp. breakfast
~10.14 Miles from 78221
Best Western Alamo Suites
+1-800-997-5149Check Rates
1002 South Laredo St., San Antonio, TX 78204
  • 4.0/5, Very Good Reviews
  • 3 star Downtown hotel
  • 72 sleeping rooms in hotel
~10.14 Miles from 78221
Holiday Inn Express Downtown Market Area
+1-800-230-4134Check Rates
102 El Paso St., San Antonio, TX 78204
  • 3.5/5, Average Read Reviews
  • Affordable Downtown property
  • Check-in: 3:00 PM
~10.27 Miles from 78221
Fairfield Inn & Suites Downtown Market Square
+1-800-997-5148Check Rates
620 South Santa Rosa, San Antonio, TX 78204
  • 4.0/5, Very Good Read Reviews
  • Economy Downtown property
  • Free complimentary breakfast
~10.40 Miles from 78221
Residence Inn by Marriott Downtown Market Square
+1-800-997-5149Check Rates
628 South Santa Rosa, San Antonio, TX 78204
  • 4.0/5, Very Good Guest Reviews
  • Three Star Downtown hotel
  • 95 sleeping rooms in hotel
~10.42 Miles from 78221
Marriott Plaza San Antonio : 555 South Alamo
+1-800-230-4134Check Rates
555 South Alamo, San Antonio, TX 78205
  • 4.0/5, Very Good Review Score
  • Expensive Downtown property
  • Fitness / Gym is on-site
~10.44 Miles from 78221
Courtyard Downtown Market Square
+1-800-997-5148Check Rates
600 South Santa Rosa, San Antonio, TX 78204
  • 4.0/5, Very Good Hotel Reviews
  • Three Star Downtown hotel
  • Hotel has 2 meeting rooms
~10.44 Miles from 78221
La Quinta Inn & Suites Downtown : 100 West Durango St.
+1-800-997-5149Check Rates
100 West Durango St., San Antonio, TX 78204
  • 4.0/5, Very Good Reviews
  • Midscale Downtown property
  • Hotel has 11 suites
~10.45 Miles from 78221
Hyatt Place San Antonio Riverwalk : 601 South St. Mary's St.
+1-800-230-4134Check Rates
601 South St. Mary's St., San Antonio, TX 78205
  • Three Star Downtown property
  • 131 suites in hotel
~10.45 Miles from 78221
Hampton Inn & Suites Downtown / Market Square in San Antonio
+1-800-997-5148Check Rates
411 South Flores St., San Antonio, TX 78205
  • Mid-scale Downtown property
  • Free breakfast
~10.48 Miles from 78221
Inn on the Riverwalk : 129 Woodward Place
+1-800-997-5149Check Rates
129 Woodward Place, San Antonio, TX 78204~10.49 Miles from 78221
Holiday Inn San Antonio Downtown Market Square
+1-800-230-4134Check Rates
318 West Cesar Chavez Blvd., San Antonio, TX 78204
  • 3.5/5, Average Reviews
  • 3 star Downtown property
  • 310 rooms in property
~10.51 Miles from 78221
Holiday Inn San Antonio Downtown Market Square : 318 West Durango Blvd.
+1-800-997-5148Check Rates
318 West Durango Blvd., San Antonio, TX 78204
  • Mid-scale Downtown hotel
  • Hotel has 6 meeting rooms
~10.51 Miles from 78221
La Cascada - San Antonio
+1-800-997-5149Check Rates
226 Dwyer Ave., San Antonio, TX 78204
  • 3 star Downtown hotel
  • Gym / Fitness Center Available
~10.54 Miles from 78221
The Fairmount Hotel in San Antonio
+1-800-230-4134Check Rates
401 South Alamo, San Antonio, TX 78205
  • 3.0/5, Average Review Score
  • 3-star Downtown hotel
  • 37 rooms in hotel
~10.56 Miles from 78221
Doubletree by Hilton San Antonio Downtown : 502 West Cesar East Chavez Blvd.
+1-800-997-5148Check Rates
502 West Cesar East Chavez Blvd., San Antonio, TX 78207
  • 3.5/5, Average Reviews
  • Affordable Downtown hotel
  • 11 conference rooms in property
~10.56 Miles from 78221
O'brien Hotel An Ascend Collection Hotel
+1-800-997-5149Check Rates
116 Navarro St., San Antonio, TX 78205
  • 4.0/5, Very Good Read Reviews
  • Three Star Downtown property
  • 3 floors in hotel
~10.60 Miles from 78221
Carefree Inn in San Antonio
+1-800-230-4134Check Rates
100 Valley Hi Dr., San Antonio, TX 78227
  • 2.5/5, Poor Read Reviews
  • Two star Suburban property
  • Comp. Breakfast
~10.63 Miles from 78221
Staybridge Suites Downtown Sunset Station
+1-800-997-5148Check Rates
123 Hoefgen Ave., San Antonio, TX 78205
  • Three Star Downtown property
  • Check in time: 3:00pm
~10.66 Miles from 78221
Riverwalk Plaza Hotel & Suites
+1-800-997-5149Check Rates
100 Villita St., San Antonio, TX 78205
  • 3.5/5, Average Guest Reviews
  • Affordable Downtown property
  • Fitness / Gym is on-site
~10.67 Miles from 78221
Hilton Palacio Del Rio in San Antonio
+1-800-230-4134Check Rates
200 South Alamo St., San Antonio, TX 78205
  • 4.0/5, Very Good Guest Reviews
  • 4 star Downtown property
  • Hotel has 10 suites
~10.68 Miles from 78221
Grand Hyatt San Antonio - San Antonio
+1-800-997-5148Check Rates
600 East Market St., San Antonio, TX 78205
  • 4.0/5, Very Good Review Score
  • 4-star Downtown hotel
  • Hotel has 24 floors
~10.70 Miles from 78221
La Hacienda Inn by Knights Inn in San Antonio
+1-800-997-5149Check Rates
1524 East Commerce St., San Antonio, TX 78205
  • 4.0/5, Very Good Recent Reviews
  • 2-star Convention Center property
  • Check-in time: 3:00 pm
~10.71 Miles from 78221
Cityview Inn & Suites Sunset Station
+1-800-230-4134Check Rates
1306 East Commerce, San Antonio, TX 78205
  • 4.0/5, Very Good Hotel Reviews
  • 2 star Downtown hotel
  • 3 floors in property
~10.72 Miles from 78221
Hotel Contessa Riverwalk Luxury Suites in San Antonio
+1-800-997-5148Check Rates
306 West Market St., San Antonio, TX 78205
  • 4.5/5, Very Good Review Score
  • High-end Downtown hotel
  • Hotel has 10 meeting rooms
~10.72 Miles from 78221
La Quinta Market Square : 900 Dolorosa
+1-800-997-5149Check Rates
900 Dolorosa, San Antonio, TX 78207~10.73 Miles from 78221
Homewood Suites by Hilton Riverwalk
+1-800-230-4134Check Rates
432 West Market St., San Antonio, TX 78205
  • 4.0/5, Very Good Guest Reviews
  • 3-star Downtown hotel
  • 146 sleeping rooms in hotel
~10.73 Miles from 78221
Best Western Plus Sunset Suites Riverwalk
+1-800-997-5148Check Rates
1103 East Commerce, San Antonio, TX 78205
  • 4.5/5, Very Good Read Reviews
  • Mid-scale Downtown property
  • 64 sleeping rooms in hotel
~10.74 Miles from 78221
Westin Riverwalk
+1-800-997-5149Check Rates
420 West Market, San Antonio, TX 78205
  • Expensive Downtown property
  • 473 rooms in property
~10.74 Miles from 78221
The Westin Riverwalk
+1-800-230-4134Check Rates
420 West Market St., San Antonio, TX 78205
  • 4.5/5, Very Good Read Reviews
  • Expensive Downtown property
  • 10 meeting rooms in hotel
~10.74 Miles from 78221
Motel 6 Market Square
+1-800-997-5148Check Rates
211 North Pecos St., San Antonio, TX 78207
  • Economy hotel
  • 119 sleeping rooms in hotel
~10.74 Miles from 78221
Holiday Inn Express Suites Rivercenter
+1-800-997-5149Check Rates
1309 East Commerce St., San Antonio, TX 78205
  • 4.0/5, Very Good Reviews
  • 3 star Downtown hotel
  • Gym is available on property
~10.75 Miles from 78221
Drury Plaza River Walk San Antonio
+1-800-230-4134Check Rates
105 South St. Mary's St., San Antonio, TX 78205
  • Affordable Downtown hotel
  • 23 floors in hotel
~10.76 Miles from 78221
San Antonio Marriott Rivercenter & Riverwalk Hotel - San Antonio
+1-800-997-5148Check Rates
101 Bowie St., San Antonio, TX 78205
  • 4 star Downtown hotel
  • Hotel has 38 floors
~10.78 Miles from 78221



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