Residence Inn Jacksonville East

4905 San Pablo Rd. South, Jacksonville, FL 32224 United States (USA)
View map Reservations: 1-800-219-2797
3.0 Star property
30.255148 -81.436060
+1-800-219-2797
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Check current prices






Standard prices by room type for the next 60 days

Rates shown are nightly rates before taxes and do not necessarily reflect all discounts available. The chart provides the cheapest public rates available by room type.

Room types

Check rates 1 Bedroom 2 Rooms Suite 2 Queen Beds Sofa
Non-smoking
Check rates 1 Bedroom Studio Suite
Non-smoking
Check rates 1 Bedroom Studio Suite 2 Queen Beds Sofa
Non-smoking
Check rates 1 Bedroom Studio Suite 2 Queen Beds Sofa Accessible
Non-smoking
Check rates 1 Bedroom Studio Suite Accessible
Non-smoking
Check rates 1 Bedroom Suite 2 Queen Sofa Bed Full Kitchen Microwave 560sqft 50sqm
Non-smoking
Check rates Discover Jacksonville Includes Buffet Breakfast Parking 1 Bedroom Suite 2 Queen Sofa Bed Full Kitche
Non-smoking
Check rates Discover Jacksonville Includes Buffet Breakfast Parking King Suite 1 King Sofa Bed Full Kitchen Micr
Non-smoking
Check rates Escape! Dining Package Includes Breakfast For 2 Guests 1 Bedroom Suite 2 Queen Sofa Bed Full Kitchen
Non-smoking
Check rates Escape! Dining Package Includes Breakfast For 2 Guests King Corner Studio 1 King Sofa Bed Full Kitch
Non-smoking
Check rates Escape! Dining Package Includes Breakfast For 2 Guests King Suite 1 King Sofa Bed Full Kitchen Micro
Non-smoking
Check rates Grand Getaways King Corner Studio 1 King Sofa Bed Full Kitchen Microwave 533sqft 48sqm
Non-smoking
Check rates International Package Breakfast For Up To 2 Guests Per Night 1 Bedroom Suite 2 Queen Sofa Bed Full K
Non-smoking
Check rates International Package Breakfast For Up To 2 Guests Per Night King Suite 1 King Sofa Bed Full Kitchen
Non-smoking
Check rates King Corner Studio 1 King Sofa Bed Full Kitchen Microwave 533sqft 48sqm
Non-smoking
Check rates King Suite 1 King Sofa Bed Full Kitchen Microwave 407sqft 37sqm Living Sitting
Non-smoking
Check rates Studio King Bed Sofa Corner
Non-smoking
Check rates Studio King Bed Sofa Corner Accessible
Non-smoking
Check rates Studio King Bed Sofa Large Corner
Non-smoking
Check rates Studio Suite King Bed Sofa
Non-smoking
Check rates Studio Suite King Bed Sofa Accessible
Non-smoking
Check rates in Suite Care Mayo Patient Package 1 Bedroom Suite 2 Queen Sofa Bed Full Kitchen Microwave 560sqft 5
Non-smoking
Check rates in Suite Care Mayo Patient Package King Corner Studio 1 King Sofa Bed Full Kitchen Microwave 533sqft
Non-smoking
Check rates in Suite Care Mayo Patient Package King Suite 1 King Sofa Bed Full Kitchen Microwave 407sqft 37sqm L
Non-smoking

Verified reviews of Residence Inn by Marriott Jacksonville Mayo Clinic Area

Below are the verified reviews from guests that we have booked in recently:
"Clean great people convenient"
Overall score5.0/ 5
We will be repeat customers.
(Individual traveller, booked 1 room), from US flag
12-Oct-2025 Verified review, stayed from Sun Oct 12 to Mon Oct 13 2025 at a $229.99 average nightly rate.
"Perfect and beautiful."
Overall score5.0/ 5
We had an excellent stay at this hotel while going to Mayo. They simply are the best. Everyone from the front desk personnel to the meal servers and the housekeepers were perfect and provided excellent quality services. We would go back to this facility in the future if needed.
(Individual traveller, booked 1 room), from US flag
01-Jul-2025 Verified review, stayed from Sun Jun 29 to Tue Jul 01 2025 at a $190.50 average nightly rate.
"Our room was very clean."
Overall score5.0/ 5
Our room was very clean and the staff and front desk was very accommodating and friendly….
(Individual traveller, booked 1 room), from US flag
17-Jun-2025 Verified review, stayed from Tue Jun 17 to Wed Jun 18 2025 at a $216.99 average nightly rate.
"Comfortable Stay!"
Overall score4.0/ 5
This was a nice place to stay, even with our dog. Everyone was very cordial.
(Individual traveller, booked 1 room), from US flag
17-May-2025 Verified review, stayed from Wed May 14 to Fri May 16 2025 at a $234.99 average nightly rate.
"Superb!"
Overall score5.0/ 5
Superb! The lady that checked me in was a star! Everything was excellent!
(Individual traveller, booked 1 room), from JM flag
02-Apr-2025 Verified review, stayed from Mon Mar 31 to Thu Apr 03 2025 at a $270.99 average nightly rate.
"Very clean but over priced."
Overall score4.0/ 5
The room was very clean and comfortable but not worth almost $300. Yes it is near Mayo Clinic so they “got you” there. They provide a shuttle to the hospital it not before 7 am. The highlight of the hotel is Mark in the bar/restaurant area. He is amazing.
(Individual traveller, booked 1 room), from US flag
04-Mar-2025 Verified review, stayed from Mon Mar 03 to Tue Mar 04 2025 at a $237.99 average nightly rate.
"Best hotel stay ever!"
Overall score5.0/ 5
The rooms are clean and spacious. The employees are very hospitable. Delicious meals.
(Individual traveller, booked 1 room), from US flag
18-Jan-2025 Verified review, stayed from Mon Jan 13 to Thu Jan 16 2025 at a $276.94 average nightly rate.
"Bathroom Problems"
Overall score3.0/ 5
No water pressure from bathroom sink. Sink stopper did not hold water.
(Individual traveller, booked 1 room), from US flag
15-Jan-2025 Verified review, stayed from Tue Jan 14 to Wed Jan 15 2025 at a $328.02 average nightly rate.
"Excellent"
Overall score5.0/ 5
Could have not been better.
(Individual traveller, booked 1 room), from US flag
27-Dec-2024 Verified review, stayed from Wed Dec 18 to Thu Dec 19 2024 at a $225.99 average nightly rate.
"MAYO Clinic Location is PERFECT; Very Quiet, Comfortable, Slept Well."
Overall score5.0/ 5
We wanted a Marriott property to use points and stay near the Mayo Clinic. This Residence Inn was perfect! So quiet which gave us a wonderful environment for a goodnight's sleep. Loved the mini kitchen to keep chilled food items. Enjoyed the large flat screen TV that swiveled around to watch in either of the two rooms. Excellent Marriott linens; awesome shower. Superb breakfast included. Too cold to go swim outside, but hopefully will someday. We'll return for our annual Mayo visits.
(Individual traveller, booked 1 room), from US flag
23-Oct-2024 Verified review, stayed from Thu Oct 17 to Sat Oct 19 2024 at a $213.01 average nightly rate.
4.0 out of 5. Based on 6 guest reviews

Details / Other expenses

Check-in: 15:00
Floors: 0
Rooms: 0
Non-smoking rooms: 0
Rooms with disabled access: 0
Suites: 0
Meeting rooms: 0
Policies / Expenses

Amenities / Features


  • Elevator

Pet friendly?

Service animals complying with ADA Title lll regulations are allowed.

Sorry but pets are not allowed.

About Residence Inn by Marriott

  • Extended stay hotel offering large 1- and 2- bedroom suites and studio suites
  • Full kitchens with refrigerators, microwaves, stoves, and coffee makers
  • Free hot breakfast and free Wi-Fi everywhere
  • Complimentary evening socials offering food and drinks for guests
  • Fitness center with modern equipment and TVs
  • Great outdoor space with barbeque and fire pits
  • Private meeting spaces perfect for events and family gatherings
  • Free grocery delivery service available
  • Dry cleaning and on-site laundry services
  • Pet friendly

The Residence Inn by Marriott highlights above are subject to change without notice.

FAQs about Residence Inn by Marriott Jacksonville Mayo Clinic Area

What time is check in?

Check in time is 15:00 based on the hotel's local time. Early check in may be available if requested at the front desk on the day of check-in.

Can I get a AAA rate at Residence Inn by Marriott Jacksonville Mayo Clinic Area?

Yes, they have stay dates that support AAA hotel discounts. Example room type: AAA CAA Hot Deals Membership Card Required 1 Bedroom Suite 2 Queen Sofa Bed Full Kitchen Microwave 5

Can I get a Senior or AARP rate at Residence Inn by Marriott Jacksonville Mayo Clinic Area?

Sorry, this hotel does not offer senior hotel discounts at this time.

Testimonials:

Testimonials icon
"This is a wonderful service when you're planning such a huge event. It really puts the mind at ease!! I just want to say Thank You!! One more thing that I can knock off my never ending list of things to do!! " S.T. - Reno, NV

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