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Sikeston Missouri Accommodations

Find the perfect hotel in Sikeston using our hotel guide provided below. Search for cheap and discounted hotel and motel rates in or near Sikeston, MO for your business or personal leisure travel. We list the best Sikeston Missouri hotel rooms. Review the Sikeston hotel list below to find the perfect lodging. We also have a map of the Sikeston hotels. Coordinating a group? Get Sikeston Group Hotel Discounts

Sikeston Hotels, Motels & Accommodations

Holiday Inn Express & Suites Sikeston : 115 Hospitality Dr. 115 Hospitality Dr., Sikeston, MO 63801
  • Economical property
  • Hotel has 73 rooms
Days Inn Sikeston : 1330 South Main St. 1330 South Main St., Sikeston, MO 63801
  • Two star property
  • Check in time: 11:00 AM
Pear Tree Inn Sikeston 2602 East Malone, Sikeston, MO 63801
  • Mid-scale Suburban hotel
  • Hotel has 4 floors
  • Excellent value
  • Vibe was good
Super 8
+1-888-283-3404
2609 East Malone Ave., Sikeston, MO 63801
  • Low priced Convention Center property
  • 62 rooms in hotel
Drury Inn & Suites Sikeston : 2608 East Malone Ave. 2608 East Malone Ave., Sikeston, MO 63801
  • Three Star Highway property
  • 5 floors in property
  • Excellent breakfast
  • Clean hotel facilities
Comfort Inn & Suites in Sikeston
+1-866-429-5787
109 Matthews Lane, Sikeston, MO 63801
  • Three Star Highway property
  • 64 rooms in hotel
  • Very good and friendly staff
  • Pool is mediocre
Country Hearth Inn & Suites Sikeston 100 Matthews Lane, Sikeston, MO 63801
  • Low Cost Highway hotel
  • Check-in: 3:00 PM
  • Service could be friendlier
  • Driveway damaged
Americas Best Value Inn & Suites : 220 South Interstate Dr. 220 South Interstate Dr., Sikeston, MO 63801
  • 2 star property
  • Check-in: 03:00 PM
Best Western Plus Sikeston : 120 South Interstate Dr. 120 South Interstate Dr., Sikeston, MO 63801
  • Economical Highway hotel
  • Gym is available on property
From$75
Very Good 4.5 /5Reviews CallBookMore Details
Quality Inn - Charleston 102 Drake St., Charleston, MO 63834 ~12.72 miles east of Sikeston
  • 2-star Highway hotel
  • 40 rooms in property
From$67
Average 3.5 /5Reviews CallBookMore Details
Super 8 310 South Story, Charleston, MO 63834 ~14.40 miles east of Sikeston
  • Low Cost Highway hotel
  • Check in: 3:00pm
Econo Lodge - Dexter 913 Outer Rd., Dexter, MO 63841 ~22.31 miles west of Sikeston
  • Two star property
  • 38 sleeping rooms in hotel
Hickory House Inn
+1-866-429-5787
1802 North Outer Rd., Dexter, MO 63841 ~23.35 miles west of Sikeston
  • Two star hotel
  • Free breakfast
Quality Inn in Cairo 13201 Kessler Rd., Cairo, IL 62914 ~23.62 miles east of Sikeston
  • 3-star hotel
  • 38 sleeping rooms in hotel
Travelodge 301 Route Ad, Marston, MO 63866 ~25.50 miles south of Sikeston
  • Inexpensive Highway property
  • 60 rooms in hotel
Candlewood Suites Cape Girardeau 485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~27.56 miles north of Sikeston
  • Low Cost Highway hotel
  • 85 rooms in property
From$55
Very Good 4.0 /5Reviews CallBookMore Details
Pear Tree Inn Cape Girardeau West : 103 Cape West Pkwy. 103 Cape West Pkwy., Cape Girardeau, MO 63701 ~28.29 miles north of Sikeston
  • Cheap property
  • 2 suites in hotel
Holiday Inn Express & Suites Cape Girardeau I 55 - Cape Girardeau
+1-888-283-3404
3253 William St., Cape Girardeau, MO 63701 ~28.33 miles north of Sikeston
  • Low Cost property
  • 102 suites in hotel
Victorian Inn & Suites
+1-866-221-8581
3256 William St., Cape Girardeau, MO 63703 ~28.38 miles north of Sikeston
  • 3 star Golf Course property
  • Hotel has 2 floors
Auburn Place Hotel & Suites in Cape Girardeau 3265 Williams St., Cape Girardeau, MO 63702 ~28.39 miles north of Sikeston
  • Mid-scale Highway hotel
  • Check-in time: 0300 pm
  • Excellent wellness & sports facilities
  • Most guests said the beds were comfortable
Drury Suites Cape Girardeau : 3303 Campster Dr. 3303 Campster Dr., Cape Girardeau, MO 63701 ~28.41 miles north of Sikeston
  • 3-star Highway property
  • 79 suites in property
  • Free breakfast
  • Free dinner
Pear Tree Inn Cape Girardeau Medical Center - Cape Girardeau 3248 William St., Cape Girardeau, MO 63701 ~28.43 miles north of Sikeston
  • Inexpensive Highway hotel
  • Hotel has an eco-friendly policy Learn more
  • Scary noises
  • Marvelous sunset
Drury Lodge Cape Girardeau 104 South Vantage Dr., Cape Girardeau, MO 63701 ~28.63 miles north of Sikeston
  • Mid-scale Highway property
  • 139 rooms in property
  • Delicious free breakfast
  • Close to Walmart
Drury Plaza Hotel & Conference Center Cape Girardeau - Cape Girardeau 3351 Percy Dr., Cape Girardeau, MO 63701 ~28.65 miles north of Sikeston
  • Mid-scale hotel
Super 8 Cape Girardeau 2011 North Kingshighway, Cape Girardeau, MO 63701 ~30.79 miles north of Sikeston
  • 2 star hotel
  • Check-in time: 11:00 AM
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