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Sikeston Missouri Accommodations

Find the perfect hotel in Sikeston using our hotel guide provided below. Search for cheap and discounted hotel and motel rates in or near Sikeston, MO for your business or personal leisure travel. We list the best Sikeston Missouri hotel rooms. Review the Sikeston hotel list below to find the perfect lodging. We also have a map of the Sikeston hotels. Coordinating a group? Get Sikeston Group Hotel Discounts

Sikeston Hotels/Accommodations

Holiday Inn Express & Suites Sikeston 115 Hospitality Dr., Sikeston, MO 63801
  • Economical property
  • 73 rooms in hotel
Days Inn Sikeston - Sikeston
+1-888-305-3366
1330 South Main St., Sikeston, MO 63801
  • Low Cost hotel
  • Check-in: 11:00 AM
Pear Tree Inn Sikeston in Sikeston 2602 East Malone, Sikeston, MO 63801
  • Midscale Suburban property
  • Check in time: 3:00 PM
  • Most guests thought the building was wonderful
  • Great pool
Super 8 in Sikeston
+1-888-283-3404
2609 East Malone Ave., Sikeston, MO 63801
  • Two star Convention Center property
  • Check in: 01:00
From$44
Average 3.0 /5Reviews CallBookMore Details
Drury Inn & Suites Sikeston in Sikeston 2608 East Malone Ave., Sikeston, MO 63801
  • Mid-scale Highway hotel
  • Fitness / Gym is on-site
  • Modern Hotel
  • Popular among families
Comfort Inn & Suites
+1-866-429-5787
109 Matthews Lane, Sikeston, MO 63801
  • 3-star Highway hotel
  • Hotel has 64 rooms
  • Average beds
  • Location is ok
From$80
Average 3.5 /5Reviews CallBookMore Details
Country Hearth Inn & Suites Sikeston - Sikeston 100 Matthews Lane, Sikeston, MO 63801
  • Two-star Highway property
  • Check in: 3:00 PM
  • Linens worn out
  • Almost all guests complained about the bathroom
Americas Best Value Inn & Suites 220 South Interstate Dr., Sikeston, MO 63801
  • Two star property
  • Hotel has 60 rooms
From$53
Very Good 4.0 /5Reviews CallBookMore Details
Best Western Plus Sikeston in Sikeston 120 South Interstate Dr., Sikeston, MO 63801
  • 2 star Highway property
  • Check-in: 3:00 PM
From$69
Very Good 4.5 /5Review Score CallBookMore Details
Quality Inn 102 Drake St., Charleston, MO 63834 ~12.72 miles east of Sikeston
  • Cheap Highway property
  • Check-in: 3:00PM
Super 8 : 310 South Story 310 South Story, Charleston, MO 63834 ~14.40 miles east of Sikeston
  • Economy Highway hotel
  • Complimentary breakfast is offered
Econo Lodge 913 Outer Rd., Dexter, MO 63841 ~22.31 miles west of Sikeston
  • 2 star property
  • Hotel has 38 rooms
Hickory House Inn - Dexter
+1-866-429-5787
1802 North Outer Rd., Dexter, MO 63841 ~23.35 miles west of Sikeston
  • Low-priced hotel
  • Comp. Breakfast
Quality Inn : 13201 Kessler Rd. 13201 Kessler Rd., Cairo, IL 62914 ~23.62 miles east of Sikeston
  • Midscale hotel
  • Free complimentary breakfast
Travelodge - Marston 301 Route Ad, Marston, MO 63866 ~25.50 miles south of Sikeston
  • Two-star Highway property
  • 60 sleeping rooms in hotel
From$40
Average 3.5 /5Reviews CallBookMore Details
Candlewood Suites Cape Girardeau 485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~27.56 miles north of Sikeston
  • Economical Highway hotel
  • 85 sleeping rooms in hotel
From$55
Very Good 4.0 /5Reviews CallBookMore Details
Pear Tree Inn Cape Girardeau West : 103 Cape West Pkwy. 103 Cape West Pkwy., Cape Girardeau, MO 63701 ~28.29 miles north of Sikeston
  • Low Cost hotel
  • Free breakfast available
Holiday Inn Express & Suites Cape Girardeau I 55 - Cape Girardeau
+1-888-283-3404
3253 William St., Cape Girardeau, MO 63701 ~28.33 miles north of Sikeston
  • Low-priced property
  • 102 rooms in hotel
From$60
Very Good 4.5 /5Reviews CallBookMore Details
Victorian Inn & Suites - Cape Girardeau
+1-866-221-8581
3256 William St., Cape Girardeau, MO 63703 ~28.38 miles north of Sikeston
  • 3 star Golf Course hotel
  • Check in: 3:00 pm
Auburn Place Hotel & Suites 3265 Williams St., Cape Girardeau, MO 63702 ~28.39 miles north of Sikeston
  • 3-star Highway hotel
  • Gym is available on property
  • Nice rooms
  • Clean
Drury Suites Cape Girardeau 3303 Campster Dr., Cape Girardeau, MO 63701 ~28.41 miles north of Sikeston
  • Affordable Highway property
  • Gym / Fitness Center Available
  • Very clean and comfortable room
  • Terrific location
Pear Tree Inn Cape Girardeau Medical Center : 3248 William St. 3248 William St., Cape Girardeau, MO 63701 ~28.43 miles north of Sikeston
  • 2 star Highway property
  • Check-in time: 3:00 pm
  • Staff was very nice and knowledgeable
  • Most guests complained about the bathroom
Drury Lodge Cape Girardeau - Cape Girardeau 104 South Vantage Dr., Cape Girardeau, MO 63701 ~28.63 miles north of Sikeston
  • 3-star Highway hotel
  • 139 sleeping rooms in hotel
  • Staff were very welcoming
  • About half of guests said rooms were small
Super 8 Cape Girardeau in Cape Girardeau 2011 North Kingshighway, Cape Girardeau, MO 63701 ~30.79 miles north of Sikeston
  • Two-star property
  • Check-in time: 11:00 AM
Comfort Suites Jackson / Cape Girardeau - Jackson 2904 Old Orchard Rd., Jackson, MO 63755 ~32.09 miles north of Sikeston
  • Affordable Highway hotel
  • 64 suites in property
  • Most guests thought the building was wonderful
  • Spacious rooms
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