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Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates

Charleston Hotels & Accommodations

Super 8 - Charleston 310 South Story, Charleston, MO 63834
  • 2 star Highway property
  • Check in: 3:00pm
From$49
Average 3.5 /5Reviews CallBookMore Details
Quality Inn 102 Drake St., Charleston, MO 63834
  • 2-star Highway property
  • Check in: 3:00PM
Best Western Plus Sikeston : 120 South Interstate Dr. 120 South Interstate Dr., Sikeston, MO 63801 ~11.05 miles west of Charleston
  • Low-priced Highway property
  • Free complimentary breakfast
From$74
Very Good 4.5 /5Read Reviews CallBookMore Details
Motel 6 Sikeston Mo 110 South Interstate Dr., Sikeston, MO 63801 ~11.07 miles west of Charleston
  • Two star hotel
  • 2 floors in hotel
From$60
Average 3.0 /5Reviews CallBookMore Details
Americas Best Value Inn & Suites in Sikeston 220 South Interstate Dr., Sikeston, MO 63801 ~11.09 miles west of Charleston
  • Low-priced hotel
  • 60 suites in hotel
Quality Inn in Cairo 13201 Kessler Rd., Cairo, IL 62914 ~11.20 miles northeast of Charleston
  • 3 star property
  • Check in time: 11:00
Country Hearth Inn & Suites Sikeston - Sikeston 100 Matthews Lane, Sikeston, MO 63801 ~11.37 miles west of Charleston
  • Two star Highway hotel
  • Hotel has 2 floors
  • Not very clean
  • Average beds
Comfort Inn & Suites - Sikeston
+1-888-690-5247
109 Matthews Lane, Sikeston, MO 63801 ~11.37 miles west of Charleston
  • Affordable Highway property
  • 3 floors in property
  • Very good and friendly staff
  • Pool is mediocre
Drury Inn & Suites Sikeston : 2608 East Malone Ave. 2608 East Malone Ave., Sikeston, MO 63801 ~11.45 miles west of Charleston
  • 3-star Highway property
  • 5 floors in property
  • Terrific location
  • Strong WIFI
Super 8 in Sikeston
+1-800-881-1523
2609 East Malone Ave., Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Inexpensive Convention Center property
  • Free breakfast
Pear Tree Inn Sikeston - Sikeston 2602 East Malone, Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Midscale Suburban property
  • 80 sleeping rooms in hotel
  • Modern Hotel
  • New towels
Holiday Inn Express & Suites Sikeston 115 Hospitality Dr., Sikeston, MO 63801 ~14.33 miles west of Charleston
  • Economy property
  • Gym / Fitness Center Available
Days Inn Sikeston in Sikeston 1330 South Main St., Sikeston, MO 63801 ~14.44 miles west of Charleston
  • 2-star hotel
  • Check in time: 11:00 AM
Americas Best Value Inn : 128 Cheekwood Lane 128 Cheekwood Lane, Ullin, IL 62992 ~25.98 miles north of Charleston
  • Low-priced property
Candlewood Suites Cape Girardeau : 485 South Mount Auburn Rd. 485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~28.61 miles northwest of Charleston
  • Two-star Highway hotel
  • 4 floors in property
Hampton Inn Cape Girardeau I 55 East 207 South Mount Auburn Rd., Cape Girardeau, MO 63703 ~29.33 miles northwest of Charleston
  • Mid-scale hotel
  • 4 floors in hotel
From$80
Excellent 5.0 /5Reviews CallBookMore Details
Victorian Inn & Suites - Cape Girardeau
+1-800-881-1523
3256 William St., Cape Girardeau, MO 63703 ~29.40 miles northwest of Charleston
  • Midscale Golf Course hotel
  • Hotel has 133 rooms
Auburn Place Hotel & Suites - Cape Girardeau 3265 Williams St., Cape Girardeau, MO 63702 ~29.41 miles northwest of Charleston
  • Affordable Highway hotel
  • Fitness center on property
  • Room was clean
  • Great amenities
From$99
Very Good 4.0 /5Read Reviews CallBookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 in Cape Girardeau
+1-866-221-8581
3253 William St., Cape Girardeau, MO 63701 ~29.43 miles northwest of Charleston
  • Cheap hotel
  • Fitness / Gym is on-site
Pear Tree Inn Cape Girardeau West 103 Cape West Pkwy., Cape Girardeau, MO 63701 ~29.49 miles northwest of Charleston
  • Low-priced hotel
  • Hotel has an eco-friendly policy Learn more
Pear Tree Inn Cape Girardeau Medical Center : 3248 William St. 3248 William St., Cape Girardeau, MO 63701 ~29.50 miles northwest of Charleston
  • Economical Highway property
  • Free breakfast
  • Easily accessible by car, said 95%
  • Most guests enjoyed the restaurants & bars nearby
Drury Suites Cape Girardeau - Cape Girardeau 3303 Campster Dr., Cape Girardeau, MO 63701 ~29.60 miles northwest of Charleston
  • 3 star Highway property
  • 79 suites in hotel
  • Spacious rooms
  • Excellent family hotel
From$94
Very Good 4.5 /5Reviews CallBookMore Details
Drury Lodge Cape Girardeau in Cape Girardeau 104 South Vantage Dr., Cape Girardeau, MO 63701 ~29.76 miles northwest of Charleston
  • Midscale Highway property
  • Access to gym on-site
  • Fair breakfast prices
  • Good alcoholic drinks
Drury Plaza Hotel & Conference Center Cape Girardeau in Cape Girardeau 3351 Percy Dr., Cape Girardeau, MO 63701 ~29.79 miles northwest of Charleston
  • Mid-scale property
  • 8 floors in hotel
Travelodge 301 Route Ad, Marston, MO 63866 ~31.28 miles southwest of Charleston
  • Economical Highway hotel
  • Check in: 3:00 PM
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