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Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates

Charleston Hotels, Motels & Accommodations

Super 8 310 South Story, Charleston, MO 63834
  • Two star Highway hotel
  • 7 suites in hotel
From$49
Average 3.5 /5Reviews CallBookMore Details
Quality Inn : 102 Drake St. 102 Drake St., Charleston, MO 63834
  • Two-star Highway property
  • Hotel has 40 rooms
Best Western Plus Sikeston in Sikeston 120 South Interstate Dr., Sikeston, MO 63801 ~11.05 miles west of Charleston
  • Economy Highway property
  • Check in: 3:00 PM
From$69
Very Good 4.5 /5Reviews CallBookMore Details
Americas Best Value Inn & Suites 220 South Interstate Dr., Sikeston, MO 63801 ~11.09 miles west of Charleston
  • Low Cost hotel
  • Hotel has 60 rooms
From$53
Very Good 4.0 /5Reviews CallBookMore Details
Quality Inn 13201 Kessler Rd., Cairo, IL 62914 ~11.20 miles northeast of Charleston
  • Three Star hotel
  • Check in: 11:00
Country Hearth Inn & Suites Sikeston 100 Matthews Lane, Sikeston, MO 63801 ~11.37 miles west of Charleston
  • Low-priced Highway property
  • Check in: 3:00 PM
  • Service is unsatisfactory
  • Average amenities
Comfort Inn & Suites : 109 Matthews Lane
+1-888-690-5281
109 Matthews Lane, Sikeston, MO 63801 ~11.37 miles west of Charleston
  • 3 star Highway property
  • Fitness center on property
  • Location is ok
  • Staff friendly
Drury Inn & Suites Sikeston : 2608 East Malone Ave. 2608 East Malone Ave., Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Midscale Highway hotel
  • 5 floors in hotel
  • Nice rooms
  • Great location
From$85
Very Good 4.5 /5Read Reviews CallBookMore Details
Super 8 : 2609 East Malone Ave.
+1-888-305-3366
2609 East Malone Ave., Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Low Cost Convention Center hotel
  • Check-in time: 01:00
Pear Tree Inn Sikeston 2602 East Malone, Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Affordable Suburban property
  • Hotel has 2 suites
  • Staff was very helpful and accommodating
  • Most guests appreciated the modern rooms
Holiday Inn Express & Suites Sikeston : 115 Hospitality Dr. 115 Hospitality Dr., Sikeston, MO 63801 ~14.33 miles west of Charleston
  • Economical property
  • Fitness center on property
From$60
Very Good 4.5 /5Review Score CallBookMore Details
Days Inn Sikeston : 1330 South Main St.
+1-866-221-8581
1330 South Main St., Sikeston, MO 63801 ~14.44 miles west of Charleston
  • 2 star hotel
  • Check-in time: 11:00 AM
Americas Best Value Inn 128 Cheekwood Lane, Ullin, IL 62992 ~25.98 miles north of Charleston
  • 2 star hotel
From$60
Very Good 4.0 /5Read Reviews CallBookMore Details
Candlewood Suites Cape Girardeau - Cape Girardeau 485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~28.61 miles northwest of Charleston
  • Two-star Highway property
  • Has environment-friendly policy See more
From$55
Very Good 4.0 /5Read Reviews CallBookMore Details
Victorian Inn & Suites : 3256 William St.
+1-888-690-5247
3256 William St., Cape Girardeau, MO 63703 ~29.40 miles northwest of Charleston
  • 3 star Golf Course property
  • 2 floors in hotel
Auburn Place Hotel & Suites 3265 Williams St., Cape Girardeau, MO 63702 ~29.41 miles northwest of Charleston
  • Affordable Highway hotel
  • Access to gym on-site
  • Most guests enjoyed the restaurants & bars nearby
  • Easily accessible by car, said 100%
Holiday Inn Express & Suites Cape Girardeau I 55 in Cape Girardeau
+1-800-881-1523
3253 William St., Cape Girardeau, MO 63701 ~29.43 miles northwest of Charleston
  • 2-star property
  • Hotel has 102 rooms
Pear Tree Inn Cape Girardeau West 103 Cape West Pkwy., Cape Girardeau, MO 63701 ~29.49 miles northwest of Charleston
  • Two star hotel
  • 81 rooms in hotel
Pear Tree Inn Cape Girardeau Medical Center in Cape Girardeau 3248 William St., Cape Girardeau, MO 63701 ~29.50 miles northwest of Charleston
  • Cheap Highway property
  • Check-in: 3:00 pm
  • Clean pool
  • TV needs to be updated
Drury Suites Cape Girardeau in Cape Girardeau 3303 Campster Dr., Cape Girardeau, MO 63701 ~29.60 miles northwest of Charleston
  • Three Star Highway property
  • Check in time: 3:00 PM
  • Fantastic service
  • Most guests thought it was clean
From$99
Very Good 4.5 /5Review Score CallBookMore Details
Drury Lodge Cape Girardeau 104 South Vantage Dr., Cape Girardeau, MO 63701 ~29.76 miles northwest of Charleston
  • 3 star Highway hotel
  • Check-in: 3:00pm
  • Rooms could be larger
  • Delicious food
Travelodge in Marston 301 Route Ad, Marston, MO 63866 ~31.28 miles southwest of Charleston
  • Two-star Highway property
  • Check in: 3:00 PM
From$40
Average 3.0 /5Reviews CallBookMore Details
Super 8 Cape Girardeau 2011 North Kingshighway, Cape Girardeau, MO 63701 ~31.73 miles northwest of Charleston
  • Cheap hotel
  • Check in: 11:00 AM
Comfort Suites Jackson / Cape Girardeau in Jackson 2904 Old Orchard Rd., Jackson, MO 63755 ~33.57 miles northwest of Charleston
  • Midscale Highway hotel
  • Hotel has an eco-friendly policy See policy
  • Mirror was dirty
  • Made our stay enjoyable
Residence Inn 3900 Coleman Crossing Circle, Paducah, KY 42001 ~34.97 miles east of Charleston
  • Affordable Suburban property
  • Free complimentary breakfast
  • Every guests reviewed said rooms were clean
  • Decent breakfast
From$89
Very Good 4.5 /5Read Reviews CallBookMore Details
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