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Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates

Charleston Hotels & Accommodations

Super 8 in Charleston 310 South Story, Charleston, MO 63834
  • Economical Highway hotel
  • 7 suites in hotel
Quality Inn 102 Drake St., Charleston, MO 63834
  • Two-star Highway hotel
  • 40 sleeping rooms in hotel
From$67
Average 3.5 /5Reviews CallBookMore Details
Best Western Plus Sikeston 120 South Interstate Dr., Sikeston, MO 63801 ~11.05 miles west of Charleston
  • Two star Highway property
  • Check-in time: 3:00 PM
From$69
Very Good 4.5 /5Review Score CallBookMore Details
Americas Best Value Inn & Suites 220 South Interstate Dr., Sikeston, MO 63801 ~11.09 miles west of Charleston
  • Low Cost hotel
  • Hotel has 2 floors
Quality Inn in Cairo 13201 Kessler Rd., Cairo, IL 62914 ~11.20 miles northeast of Charleston
  • Midscale property
  • Check-in: 11:00
Country Hearth Inn & Suites Sikeston - Sikeston 100 Matthews Lane, Sikeston, MO 63801 ~11.36 miles west of Charleston
  • Two-star Highway hotel
  • 2 floors in hotel
Comfort Inn & Suites
+1-888-690-5281
109 Matthews Lane, Sikeston, MO 63801 ~11.37 miles west of Charleston
  • 3-star Highway hotel
  • Hotel has 64 rooms
  • Very good and friendly staff
  • Friendly service
Drury Inn & Suites Sikeston 2608 East Malone Ave., Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Mid-scale Highway hotel
  • Hotel has 14 suites
  • Most guests enjoyed the snacks that were offered
  • Awesome vibe
From$85
Very Good 4.5 /5Reviews CallBookMore Details
Super 8 : 2609 East Malone Ave.
+1-888-305-3366
2609 East Malone Ave., Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Two star Convention Center hotel
  • Check-in time: 01:00
Pear Tree Inn Sikeston 2602 East Malone, Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Midscale Suburban property
  • 4 floors in hotel
  • Most guests thought, the hotel was modern
  • Clean hotel facilities
Holiday Inn Express & Suites Sikeston 115 Hospitality Dr., Sikeston, MO 63801 ~14.33 miles west of Charleston
  • Two star hotel
From$60
Very Good 4.5 /5Reviews CallBookMore Details
Days Inn Sikeston
+1-866-221-8581
1330 South Main St., Sikeston, MO 63801 ~14.44 miles west of Charleston
  • Two star hotel
  • Check-in time: 11:00 AM
Americas Best Value Inn - Ullin 128 Cheekwood Lane, Ullin, IL 62992 ~25.98 miles north of Charleston
  • 2 star property
Candlewood Suites Cape Girardeau in Cape Girardeau 485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~28.61 miles northwest of Charleston
  • 2-star Highway hotel
  • Has environment-friendly policy Read more
From$62
Very Good 4.0 /5Read Reviews CallBookMore Details
Victorian Inn & Suites - Cape Girardeau
+1-888-690-5247
3256 William St., Cape Girardeau, MO 63703 ~29.40 miles northwest of Charleston
  • 3 star Golf Course property
  • 5 suites in property
Auburn Place Hotel & Suites in Cape Girardeau 3265 Williams St., Cape Girardeau, MO 63702 ~29.41 miles northwest of Charleston
  • Three Star Highway hotel
  • Gym / Fitness Center Available
  • Most guests said the reception staff was great
  • Most guests enjoyed the restaurants & bars nearby
From$99
Very Good 4.0 /5Review Score CallBookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55
+1-800-881-1523
3253 William St., Cape Girardeau, MO 63701 ~29.43 miles northwest of Charleston
  • Cheap hotel
  • Gym is available on property
From$60
Very Good 4.5 /5Read Reviews CallBookMore Details
Pear Tree Inn Cape Girardeau West 103 Cape West Pkwy., Cape Girardeau, MO 63701 ~29.49 miles northwest of Charleston
  • Cheap hotel
  • Access to gym on-site
Pear Tree Inn Cape Girardeau Medical Center : 3248 William St. 3248 William St., Cape Girardeau, MO 63701 ~29.50 miles northwest of Charleston
  • 2 star Highway hotel
  • Free complimentary breakfast
  • Clean hotel facilities
  • Good value for the money
Drury Suites Cape Girardeau - Cape Girardeau 3303 Campster Dr., Cape Girardeau, MO 63701 ~29.60 miles northwest of Charleston
  • Mid-scale Highway hotel
  • Hotel has 79 suites
  • Friendly service
  • Tasty breakfast
From$119
Very Good 4.5 /5Hotel Reviews CallBookMore Details
Drury Lodge Cape Girardeau 104 South Vantage Dr., Cape Girardeau, MO 63701 ~29.76 miles northwest of Charleston
  • Mid-scale Highway property
  • Hotel has 2 floors
  • Free alcoholic beverages
  • Close to Walmart
Travelodge in Marston 301 Route Ad, Marston, MO 63866 ~31.28 miles southwest of Charleston
  • Economy Highway property
  • Check-in time: 3:00 PM
Super 8 Cape Girardeau 2011 North Kingshighway, Cape Girardeau, MO 63701 ~31.73 miles northwest of Charleston
  • Low-priced property
Comfort Suites Jackson / Cape Girardeau - Jackson 2904 Old Orchard Rd., Jackson, MO 63755 ~33.57 miles northwest of Charleston
  • 3-star Highway property
  • Hotel has an eco-friendly policy See more
  • Vibe was good
  • Bathroom could be optimized
Residence Inn in Paducah 3900 Coleman Crossing Circle, Paducah, KY 42001 ~34.97 miles east of Charleston
  • Mid-scale Suburban property
  • Hotel has 74 suites
  • Perfectly clean
  • Excellent breakfast
From$89
Very Good 4.5 /5Read Reviews CallBookMore Details
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