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Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates

Charleston Hotels & Accommodations

Super 8 by Wyndham Charleston MO
+1-888-389-4121
310 South Story, Charleston, MO 63834
  • 2 star Highway property
  • Complimentary breakfast is offered
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Quality Inn
+1-888-675-2083
102 Drake St., Charleston, MO 63834
  • Inexpensive Highway hotel
  • 2 floors in hotel
From$59
Average 3.0 /5Reviews CallBookMore Details
Motel 6 Sikeston Mo #4328 in SIKESTON
+1-800-716-8490
110 South Interstate Dr., SIKESTON, MISSOURI 63801 ~11.02 miles west of Charleston
  • Low Cost property
From$60
Average 3.0 /5Reviews CallBookMore Details
Best Western Plus Sikeston
+1-800-805-5223
120 South Interstate Dr., Sikeston, MO 63801 ~11.05 miles west of Charleston
  • Economy Highway hotel
  • Free breakfast
From$42
Very Good 4.5 /5Read Reviews CallBookMore Details
Days Inn and Suites by Wyndham Sikeston
+1-888-965-1860
220 South Interstate Dr., Sikeston, MO 63801 ~11.09 miles west of Charleston
  • Low Cost property
  • Access to gym on-site
Quality Inn Cairo I-57 : 13201 Kessler Rd.
+1-888-788-5576
13201 Kessler Rd., Cairo, IL 62914 ~11.20 miles northeast of Charleston
  • Affordable Highway hotel
  • 2 floors in property
  • Handicap accessible room
  • Beautiful river
Drury Inn & Suites Sikeston
+1-888-897-9207
2608 East Malone Ave., Sikeston, MO 63801 ~11.33 miles west of Charleston
  • Midscale Highway property
  • Check-in time: 3:00 PM
Super 8 by Wyndham Sikeston / Miner Area
+1-888-311-4278
2609 East Malone, Sikeston, MO 63801 ~11.36 miles west of Charleston
  • Cheap Convention Center property
  • Check-in: 01:00
Travel Inn & Suites
+1-888-469-4795
100 Matthews Lane, Sikeston, MO 63801 ~11.37 miles west of Charleston
  • Three Star Highway hotel
  • 2 floors in hotel
  • Ordinary amenities
  • Average comfort
Comfort Inn : 109 Matthews Lane
+1-888-734-9421
109 Matthews Lane, Sikeston, MO 63801 ~11.40 miles west of Charleston
  • Mid-scale Highway property
  • Check-in time: 11:00
Pear Tree Inn Sikeston - Sikeston
+1-888-841-5292
2602 East Malone, Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Midscale Suburban hotel
  • Hotel has 4 floors
  • Nice rooms
  • Hot breakfast included
From$80
Average 3.0 /5Reviews CallBookMore Details
Holiday Inn Express Sikeston : 115 Hospitality Dr.
+1-888-455-5160
115 Hospitality Dr., Sikeston, MO 63801 ~14.33 miles west of Charleston
  • Three Star Rural hotel
  • Gym is available on property
Hampton Inn Sikeston - Sikeston
+1-888-965-8297
1240 Commerce Dr., Sikeston, MO 63801 ~14.72 miles west of Charleston
  • 3-star property
  • Check-in time: 15:00
From$90
Very Good 4.5 /5Reviews CallBookMore Details
Americas Best Value Inn Ullin Mounds
+1-888-906-6358
128 Cheekwood Lane, Ullin, IL 62992 ~25.98 miles north of Charleston
  • Inexpensive hotel
  • Comp. Breakfast
Courtyard by Marriott Cape Girardeau Downtown in Cape Girardeau
+1-888-749-6785
400 Broadway St., Cape Girardeau, MO 63701 ~28.56 miles north of Charleston
  • Midscale Downtown hotel
  • Hotel has 13 suites
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Candlewood Suites Cape Girardeau, an IHG Hotel
+1-888-878-9982
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~28.61 miles northwest of Charleston
  • 2-star Highway property
  • Hotel has 85 suites
Hampton Inn Cape Girardeau I 55 East in Cape Girardeau
+1-888-389-4485
207 South Mt. Auburn Rd., Cape Girardeau, MO 63703 ~29.29 miles northwest of Charleston
  • 3-star hotel
From$69
Excellent 5.0 /5Review Score CallBookMore Details
Victorian Inn & Suites
+1-888-389-4121
3256 William St., Cape Girardeau, MO 63703 ~29.40 miles northwest of Charleston
  • Affordable Golf Course hotel
  • Comp. Breakfast
Auburn Place Hotel & Suites
+1-888-675-2083
3265 Williams St., Cape Girardeau, MO 63702 ~29.41 miles northwest of Charleston
  • Affordable Highway property
  • 2 floors in property
  • Most guests enjoyed the restaurants & bars nearby
  • Clean rooms
From$58
Very Good 4.5 /5Reviews CallBookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55
+1-800-716-8490
3253 William St., Cape Girardeau, MO 63701 ~29.43 miles northwest of Charleston
  • Inexpensive hotel
  • Hotel has 102 rooms
From$60
Very Good 4.5 /5Review Score CallBookMore Details
Pear Tree Inn Cape Girardeau West
+1-800-805-5223
103 Cape West Pkwy., Cape Girardeau, MO 63701 ~29.49 miles northwest of Charleston
  • Two star hotel
  • Has environment-friendly policy Read more
Pear Tree Inn Cape Girardeau Medical Center : 3248 William St.
+1-888-965-1860
3248 William St., Cape Girardeau, MO 63701 ~29.50 miles northwest of Charleston
  • Cheap Highway hotel
  • Free breakfast
  • Most guests said the beds were comfortable
  • Clean establishment
Drury Suites Cape Girardeau
+1-888-788-5576
3303 Campster Dr., Cape Girardeau, MO 63701 ~29.60 miles northwest of Charleston
  • 3-star Highway hotel
  • Fitness center on property
  • Separate rooms
  • Registration desk helped with
From$85
Very Good 4.5 /5Reviews CallBookMore Details
Drury Lodge : 104 South Vantage Dr.
+1-888-897-9207
104 South Vantage Dr., Cape Girardeau, MO 63701 ~29.77 miles northwest of Charleston
  • Midscale Highway property
  • Check-in time: 3:00pm
Drury Plaza Hotel & Conference Center Cape Girardeau
+1-888-311-4278
3351 Percy Dr., Cape Girardeau, MO 63701 ~29.79 miles northwest of Charleston
  • Affordable property
  • Check-in: 3pm
Next 25 Charleston Hotels >  [1 - 25 of 50]    
Next: See My Charleston Hotels with Pricing

Graph of Charleston, MO Hotel Prices for Next 20 Days

Rates shown are nightly rates before taxes and do not necessarily reflect all Charleston, MO discounts available. The chart reflects the cheapest Charleston hotel for each day and each star rating category.

FAQs about hotels in Charleston

What are the top reviewed hotels in Charleston?

Hampton Inn Cape Girardeau I 55 East, Homewood Suites by Hilton Paducah and Best Western Plus Sikeston are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels in Charleston?

Harrah's Metropolis Hotel & Casino, Quality Inn Cairo I-57 and Drury Inn & Suites Sikeston are the top 3 luxury hotels near Charleston city center.

What hotels are closest to the city center of Charleston?

Super 8 by Wyndham Charleston MO, Quality Inn, and Motel 6 Sikeston Mo #4328 are the properties closest to Charleston city center.

How much does a cheap hotel in Charleston cost per night?

In the last year, a 2 star hotel in Charleston can be as cheap as $69.99 per night. (based on HotelPlanner prices)

How much does a 3 star hotel in Charleston cost per night?

In the last year, the average 3 star hotel in Charleston has been $54.99 per night. (based on HotelPlanner prices)

What are the most popular independent hotels in Charleston?

Travel Inn & Suites, Auburn Place Hotel & Suites and Drury Suites Cape Girardeau are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Charleston?

Courtyard by Marriott Cape Girardeau Downtown and Residence Inn are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Charleston?

Sleep Inn Union City, Comfort Suites Jackson-Cape Girardeau and Mainstay Suites are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular Best Western hotels in Charleston?

Best Western Plus Sikeston and Best Western Plus Jackson are the best rated Best Western branded hotels (based on user reviews score).

What are the best IHG hotels in Charleston?

Holiday Inn Express & Suites Cape Girardeau I 55, Holiday Inn Express Sikeston and Candlewood Suites Cape Girardeau, an IHG Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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