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Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates

Charleston Hotels/Accommodations

Super 8 : 310 South Story 310 South Story, Charleston, MO 63834
  • Low Cost Highway hotel
  • 60 sleeping rooms in hotel
Quality Inn - Charleston 102 Drake St., Charleston, MO 63834
  • Low-priced Highway hotel
  • 2 floors in property
From$67
Average 3.5 /5Reviews CallBookMore Details
Best Western Plus Sikeston - Sikeston 120 South Interstate Dr., Sikeston, MO 63801 ~11.05 miles west of Charleston
  • 2 star Highway hotel
  • Free comp. breakfast
Motel 6 Sikeston Mo : 110 South Interstate Dr. 110 South Interstate Dr., Sikeston, MO 63801 ~11.07 miles west of Charleston
  • Economical property
  • Hotel has 2 floors
Americas Best Value Inn & Suites : 220 South Interstate Dr. 220 South Interstate Dr., Sikeston, MO 63801 ~11.09 miles west of Charleston
  • Two-star property
  • Check-in: 03:00 PM
Quality Inn in Cairo 13201 Kessler Rd., Cairo, IL 62914 ~11.20 miles northeast of Charleston
  • Three Star property
  • Check in: 11:00
Country Hearth Inn & Suites Sikeston 100 Matthews Lane, Sikeston, MO 63801 ~11.37 miles west of Charleston
  • Two-star Highway hotel
  • Check in time: 3:00 PM
  • Average amenities
  • Almost all guests complained about the bathroom
Comfort Inn & Suites - Sikeston
+1-888-690-5247
109 Matthews Lane, Sikeston, MO 63801 ~11.37 miles west of Charleston
  • 3-star Highway hotel
  • Check in time: 02:00 PM
  • Bathroom could be optimized
  • Popular among families
Drury Inn & Suites Sikeston in Sikeston 2608 East Malone Ave., Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Mid-scale Highway property
  • Gym is available on property
  • Rooms need regular maintenance
  • Beautiful breakfast cocktail
Super 8
+1-800-881-1523
2609 East Malone Ave., Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Cheap Convention Center hotel
  • 2 floors in property
Pear Tree Inn Sikeston : 2602 East Malone 2602 East Malone, Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Midscale Suburban hotel
  • Check in: 3:00 PM
  • Great location
  • Fantastic service
Holiday Inn Express & Suites Sikeston 115 Hospitality Dr., Sikeston, MO 63801 ~14.33 miles west of Charleston
  • Economical property
Days Inn Sikeston - Sikeston 1330 South Main St., Sikeston, MO 63801 ~14.44 miles west of Charleston
  • Two-star property
Americas Best Value Inn - Ullin 128 Cheekwood Lane, Ullin, IL 62992 ~25.98 miles north of Charleston
  • Low priced property
Candlewood Suites Cape Girardeau 485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~28.61 miles northwest of Charleston
  • 2 star Highway hotel
  • Fitness center on property
Hampton Inn Cape Girardeau I 55 East in Cape Girardeau 207 South Mount Auburn Rd., Cape Girardeau, MO 63703 ~29.33 miles northwest of Charleston
  • 3-star property
  • Check in time: 15:00
From$80
Excellent 5.0 /5Reviews CallBookMore Details
Auburn Place Hotel & Suites : 3265 Williams St. 3265 Williams St., Cape Girardeau, MO 63702 ~29.41 miles northwest of Charleston
  • Three Star Highway property
  • 5 suites in hotel
  • Nice rooms
  • About half of guests complained about the bathroom
Holiday Inn Express & Suites Cape Girardeau I 55 : 3253 William St.
+1-888-283-3404
3253 William St., Cape Girardeau, MO 63701 ~29.43 miles northwest of Charleston
  • 2 star hotel
  • 102 suites in property
Pear Tree Inn Cape Girardeau West : 103 Cape West Pkwy. 103 Cape West Pkwy., Cape Girardeau, MO 63701 ~29.49 miles northwest of Charleston
  • Inexpensive property
  • 2 suites in property
Pear Tree Inn Cape Girardeau Medical Center in Cape Girardeau 3248 William St., Cape Girardeau, MO 63701 ~29.50 miles northwest of Charleston
  • Low priced Highway hotel
  • 3 floors in hotel
  • Good continental breakfast
  • Great location
Drury Suites Cape Girardeau 3303 Campster Dr., Cape Girardeau, MO 63701 ~29.60 miles northwest of Charleston
  • Midscale Highway property
  • 86 sleeping rooms in hotel
  • Friendly service
  • Separate rooms
Drury Lodge Cape Girardeau 104 South Vantage Dr., Cape Girardeau, MO 63701 ~29.76 miles northwest of Charleston
  • 3-star Highway hotel
  • 139 rooms in hotel
  • Excellent value
  • Very cordial and welcoming front desk person
Drury Plaza Hotel & Conference Center Cape Girardeau - Cape Girardeau 3351 Percy Dr., Cape Girardeau, MO 63701 ~29.79 miles northwest of Charleston
  • 3-star property
  • Check in time: 3pm
Travelodge : 301 Route Ad 301 Route Ad, Marston, MO 63866 ~31.28 miles southwest of Charleston
  • Economy Highway property
  • Free complimentary breakfast
Super 8 Cape Girardeau : 2011 North Kingshighway 2011 North Kingshighway, Cape Girardeau, MO 63701 ~31.73 miles northwest of Charleston
  • Two star hotel
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