Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates


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Charleston Hotels/Motels & Accommodations

Photo of Super 8Super 8
+1-800-230-4134
$45+

310 South Story, Charleston, MO 63834
  • 3.5/5, Average Reviews
  • Economical Highway hotel
  • Hotel has 60 rooms
Photo of Quality InnQuality Inn : 102 Drake St.
+1-800-997-5148
$76+

102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Latest Reviews
  • Two-star Highway property
  • Free complimentary breakfast
Photo of Eagle InnEagle Inn : 2811 East Marshall St.
+1-800-997-5149
$44+

2811 East Marshall St., Charleston, MO 63834
  • 3.5/5, Average Review Score
  • Inexpensive hotel
  • Check in: 3:00PM
Image of Best Western Plus SikestonBest Western Plus Sikeston in Sikeston
+1-800-230-4134
$69+

120 South Interstate Dr., Sikeston, MO 63801
  • Inexpensive Highway hotel
  • 2 floors in property
~11.00 Miles from Charleston
Photo of Comfort Inn & SuitesComfort Inn & Suites - Sikeston
+1-800-997-5148
$80+

109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Guest Reviews
  • Midscale Highway property
  • 64 rooms in hotel
~11.37 Miles from Charleston
Exterior of Drury Inn & Suites SikestonDrury Inn & Suites Sikeston
+1-800-997-5149
$99+

2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Read Reviews
  • Midscale Highway hotel
  • 14 suites in hotel
~11.45 Miles from Charleston
Photo of Super 8Super 8 : 2609 East Malone Ave.
+1-800-230-4134
$44+

2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Hotel Reviews
  • Economical Convention Center hotel
  • Check in time: 01:00
~11.45 Miles from Charleston
Exterior of Pear Tree Inn SikestonPear Tree Inn Sikeston in Sikeston
+1-800-997-5148
$69+

2602 East Malone, Sikeston, MO 63801
  • Three Star Suburban property
  • Hotel has 2 suites
~11.45 Miles from Charleston
Exterior of Candlewood Suites Cape GirardeauCandlewood Suites Cape Girardeau : 485 South Mount Auburn Rd.
+1-800-997-5149
$69+

485 South Mount Auburn Rd., Cape Girardeau, MO 65703 Website
  • 4.0/5, Very Good Reviews
  • Economy Highway hotel
  • Hotel has 4 floors
~28.61 Miles from Charleston
Victorian Inn & Suites
+1-800-230-4134
$79+

3256 William St., Cape Girardeau, MO 63703
  • Affordable Golf Course property
  • Free comp. breakfast
~29.40 Miles from Charleston
Auburn Place Hotel & Suites : 3265 Williams St.
+1-800-997-5148
$65+

3265 Williams St., Cape Girardeau, MO 63702
  • 4.0/5, Very Good Hotel Reviews
  • 3-star Highway hotel
  • 5 suites in hotel
~29.41 Miles from Charleston
Holiday Inn Express Hotel & Suites - Cape Girardeau
+1-800-997-5149
$112+

3253 William St., Cape Girardeau, MO 63701
  • 4.5/5, Very Good Read Reviews
  • Three Star property
  • Hotel has 3 meeting rooms
~29.49 Miles from Charleston
Pear Tree Inn Cape Girardeau
+1-800-230-4134
$65+

3248 William St., Cape Girardeau, MO 63701
  • Inexpensive Highway property
  • Hotel has 3 floors
~29.50 Miles from Charleston
Drury Suites Cape Girardeau : 3303 Campster Dr.
+1-800-997-5148
$124+

3303 Campster Dr., Cape Girardeau, MO 63701
  • 4.5/5, Very Good Reviews
  • Affordable Highway property
  • 5 floors in property
~29.60 Miles from Charleston
Drury Lodge Cape Girardeau in Cape Girardeau
+1-800-997-5149
$89+

104 South Vantage Dr., Cape Girardeau, MO 63701
  • Mid-scale Highway hotel
  • 2 floors in property
~29.76 Miles from Charleston
Comfort Suites Jackson / Cape Girardeau in Jackson
+1-800-230-4134
$80+

2904 Old Orchard Rd., Jackson, MO 63755
  • 4.0/5, Very Good Guest Reviews
  • Affordable Highway property
  • Check-in time: 3.00 pm
~33.57 Miles from Charleston
Residence Inn : 3900 Coleman Crossing Circle
+1-800-997-5148
$94+

3900 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Read Reviews
  • Mid-scale Suburban property
  • Free breakfast available
~34.97 Miles from Charleston
Pear Tree Inn Paducah : 5006 Hinkleville Rd.
+1-800-997-5149
$64+

5006 Hinkleville Rd., Paducah, KY 42001
  • 4.0/5, Very Good Read Reviews
  • Cheap Suburban hotel
  • Free breakfast available
~35.47 Miles from Charleston
Econo Lodge Dexter : 913 Outer Rd.
+1-800-230-4134
$49+

913 Outer Rd., Dexter, MO 63841
  • 3.0/5, Average Hotel Reviews
  • Two-star hotel
  • Free complimentary breakfast
~36.06 Miles from Charleston
Baymont Inn & Suites Metropolis Il in Metropolis
+1-800-997-5148
$45+

203 East Front St., Metropolis, IL 62960
  • 3.0/5, Average Read Reviews
  • Cheap Riverfront property
  • 8 suites in property
~36.55 Miles from Charleston

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