Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates


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Charleston Hotels/Motels & Accommodations

Photo of Super 8Super 8 - Charleston
+1-800-230-4134Check Rates
310 South Story, Charleston, MO 63834
  • 3.5/5, Average Guest Reviews
  • 2 star Highway hotel
  • Check-in time: 3:00pm
Exterior of Quality InnQuality Inn - Charleston
+1-800-997-5148Check Rates
102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Latest Reviews
  • Two-star Highway hotel
  • Complimentary breakfast is offered
Exterior of Eagle InnEagle Inn
+1-800-997-5149Check Rates
2811 East Marshall St., Charleston, MO 63834
  • 3.5/5, Average Hotel Reviews
  • Low Cost property
  • Access to gym on-site
Photo of Best Western Plus SikestonBest Western Plus Sikeston in Sikeston
+1-800-230-4134Check Rates
120 South Interstate Dr., Sikeston, MO 63801
  • Two-star Highway hotel
  • Hotel has 55 rooms
~11.00 Miles from Charleston
Exterior of Comfort Inn & SuitesComfort Inn & Suites in Sikeston
+1-800-997-5148Check Rates
109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Reviews
  • Three Star Highway property
  • Comp. Breakfast
~11.37 Miles from Charleston
Photo of Drury Inn & Suites SikestonDrury Inn & Suites Sikeston
+1-800-997-5149Check Rates
2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Review Score
  • 3 star Highway property
  • Check-in: 3:00 PM
~11.45 Miles from Charleston
Exterior of Super 8Super 8 in Sikeston
+1-800-230-4134Check Rates
2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Guest Reviews
  • Economical Convention Center property
  • 62 rooms in property
~11.45 Miles from Charleston
Exterior of Pear Tree Inn SikestonPear Tree Inn Sikeston : 2602 East Malone
+1-800-997-5148Check Rates
2602 East Malone, Sikeston, MO 63801
  • Mid-scale Suburban hotel
  • Free comp. breakfast
~11.45 Miles from Charleston
Exterior of Candlewood Suites Cape GirardeauCandlewood Suites Cape Girardeau
+1-800-997-5149Check Rates
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 Website
  • 4.0/5, Very Good Reviews
  • Two star Highway hotel
  • Check in time: 3:00PM
~28.61 Miles from Charleston
Victorian Inn & Suites - Cape Girardeau
+1-800-230-4134Check Rates
3256 William St., Cape Girardeau, MO 63703
  • Mid-scale Golf Course hotel
  • 133 rooms in hotel
~29.40 Miles from Charleston
Auburn Place Hotel & Suites
+1-800-997-5148Check Rates
3265 Williams St., Cape Girardeau, MO 63702~29.41 Miles from Charleston
Holiday Inn Express Hotel & Suites
+1-800-997-5149Check Rates
3253 William St., Cape Girardeau, MO 63701
  • 4.5/5, Very Good Hotel Reviews
  • 3 star property
  • 150 rooms in property
~29.49 Miles from Charleston
Pear Tree Inn Cape Girardeau - Cape Girardeau
+1-800-230-4134Check Rates
3248 William St., Cape Girardeau, MO 63701
  • Economy Highway hotel
  • Hotel has 3 floors
~29.50 Miles from Charleston
Drury Suites Cape Girardeau
+1-800-997-5148Check Rates
3303 Campster Dr., Cape Girardeau, MO 63701
  • 4.5/5, Very Good Hotel Reviews
  • 3 star Highway hotel
  • Check-in: 3:00 PM
~29.60 Miles from Charleston
Drury Lodge Cape Girardeau : 104 South Vantage Dr.
+1-800-997-5149Check Rates
104 South Vantage Dr., Cape Girardeau, MO 63701
  • Three Star Highway property
  • Hotel has 2 floors
~29.76 Miles from Charleston
Comfort Suites Jackson / Cape Girardeau
+1-800-230-4134Check Rates
2904 Old Orchard Rd., Jackson, MO 63755
  • 4.0/5, Very Good Review Score
  • Mid-scale Highway property
  • Hotel has 64 suites
~33.57 Miles from Charleston
Residence Inn
+1-800-997-5148Check Rates
3900 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Latest Reviews
  • 3 star Suburban property
  • Fitness + Health Center
~34.97 Miles from Charleston
Pear Tree Inn Paducah - Paducah
+1-800-997-5149Check Rates
5006 Hinkleville Rd., Paducah, KY 42001
  • 4.0/5, Very Good Recent Reviews
  • Cheap Suburban property
  • 60 rooms in hotel
~35.47 Miles from Charleston
Econo Lodge Dexter : 913 Outer Rd.
+1-800-230-4134Check Rates
913 Outer Rd., Dexter, MO 63841
  • 3.0/5, Average Review Score
  • Low Cost property
  • 6 suites in property
~36.06 Miles from Charleston
Baymont Inn & Suites Metropolis Il
+1-800-997-5148Check Rates
203 East Front St., Metropolis, IL 62960
  • 3.0/5, Average Read Reviews
  • Cheap Riverfront hotel
  • Fitness + Health Center
~36.55 Miles from Charleston

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