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Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates

Charleston Hotels/Motels & Accommodations

Super 8 - Charleston 310 South Story, Charleston, MO 63834
  • Low Cost Highway hotel
  • 7 suites in property
From$49
Average 3.5 /5Reviews Call
Quality Inn 102 Drake St., Charleston, MO 63834
  • Inexpensive Highway property
  • 2 floors in property
  • Every guests reviewed said the beds were comfortable
  • Friendly staff
Best Western Plus Sikeston in Sikeston 120 South Interstate Dr., Sikeston, MO 63801 ~11.00 miles west of Charleston
  • Cheap Highway property
  • 55 sleeping rooms in hotel
Americas Best Value Inn & Suites 220 South Interstate Dr., Sikeston, MO 63801 ~11.09 miles west of Charleston
  • Low-priced property
  • 60 rooms in property
From$49
Very Good 4.0 /5Review Score Call
Quality Inn : 13201 Kessler Rd. 13201 Kessler Rd., Cairo, IL 62914 ~11.20 miles northeast of Charleston
  • Midscale hotel
  • Check-in time: 11:00
From$75
Very Good 4.0 /5Review Score Call
Country Hearth Inn & Suites Sikeston : 100 Matthews Lane 100 Matthews Lane, Sikeston, MO 63801 ~11.36 miles west of Charleston
  • Low Cost Highway property
  • Free complimentary breakfast
Comfort Inn & Suites - Sikeston
+1-888-283-3404
109 Matthews Lane, Sikeston, MO 63801 ~11.37 miles west of Charleston
  • Affordable Highway hotel
  • Check-in: 02:00 PM
  • Ordinary pool
  • Beds were acceptable for 67%
Drury Inn & Suites Sikeston - Sikeston 2608 East Malone Ave., Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Three Star Highway property
  • 154 rooms in property
  • Beautiful reception area
  • Great location
From$101
Very Good 4.5 /5Latest Reviews Call
Super 8
+1-888-690-5281
2609 East Malone Ave., Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Two star Convention Center property
  • Hotel has 2 floors
Pear Tree Inn Sikeston in Sikeston 2602 East Malone, Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Mid-scale Suburban property
  • Free complimentary breakfast
  • Clean hotel facilities
  • Hotel was clean and was great
Holiday Inn Express & Suites Sikeston - Sikeston
+1-800-997-5148
115 Hospitality Dr., Sikeston, MO 63801 ~14.33 miles west of Charleston
  • Two-star hotel
  • 73 rooms in property
Days Inn Sikeston in Sikeston
+1-888-690-5247
1330 South Main St., Sikeston, MO 63801 ~14.44 miles west of Charleston
  • Low Cost property
Candlewood Suites Cape Girardeau in Cape Girardeau
+1-888-305-3366
485 South Mt. Auburn Rd., Cape Girardeau, MO 63703 ~28.56 miles northwest of Charleston
  • Economy hotel
  • 85 rooms in hotel
Candlewood Suites Cape Girardeau - Cape Girardeau 485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~28.61 miles northwest of Charleston
  • Low-priced Highway hotel
  • Fitness center on property
Victorian Inn & Suites
+1-888-283-3404
3256 William St., Cape Girardeau, MO 63703 ~29.40 miles northwest of Charleston
  • Midscale Golf Course property
  • 133 sleeping rooms in hotel
Auburn Place Hotel & Suites 3265 Williams St., Cape Girardeau, MO 63702 ~29.41 miles northwest of Charleston
  • Mid-scale Highway hotel
  • Hotel has 2 floors
  • Most guests said the reception staff was great
  • Clean hotel facilities
Holiday Inn Express & Suites Cape Girardeau I 55 in Cape Girardeau
+1-888-690-5281
3253 William St., Cape Girardeau, MO 63701 ~29.43 miles northwest of Charleston
  • Cheap hotel
  • Check in time: 11:00
From$75
Very Good 4.5 /5Read Reviews Call
Pear Tree Inn Cape Girardeau Medical Center 3248 William St., Cape Girardeau, MO 63701 ~29.50 miles northwest of Charleston
  • Cheap Highway hotel
  • Check in: 3:00 pm
  • Clean establishment
  • Rooms could be larger
Drury Suites Cape Girardeau - Cape Girardeau 3303 Campster Dr., Cape Girardeau, MO 63701 ~29.60 miles northwest of Charleston
  • Affordable Highway hotel
  • 5 floors in hotel
  • Separate rooms
  • Pool should be renewed
From$119
Very Good 4.5 /5Hotel Reviews Call
Drury Lodge Cape Girardeau - Cape Girardeau 104 South Vantage Dr., Cape Girardeau, MO 63701 ~29.76 miles northwest of Charleston
  • Mid-scale Highway property
  • 139 sleeping rooms in hotel
  • Most guests thought the service was very professional
  • Average hotel building
Travelodge in Marston 301 Route Ad, Marston, MO 63866 ~31.28 miles southwest of Charleston
  • Low-priced Highway property
  • Free complimentary breakfast
Super 8 Cape Girardeau in Cape Girardeau 2011 North Kingshighway, Cape Girardeau, MO 63701 ~31.73 miles northwest of Charleston
  • Inexpensive hotel
  • Check-in time: 11:00 AM
Comfort Suites Jackson / Cape Girardeau 2904 Old Orchard Rd., Jackson, MO 63755 ~33.57 miles northwest of Charleston
  • 3 star Highway property
  • Fitness / Gym is on-site
  • Easily accessible by car
  • Fantastic service
Residence Inn : 3900 Coleman Crossing Circle 3900 Coleman Crossing Circle, Paducah, KY 42001 ~34.97 miles east of Charleston
  • Affordable Suburban property
  • Fitness center on property
  • Clean
  • Clean hotel with fantastic service
From$91
Very Good 4.5 /5Reviews Call
Pear Tree Inn Paducah - Paducah 5006 Hinkleville Rd., Paducah, KY 42001 ~35.47 miles east of Charleston
  • Low priced Suburban property
  • Has environment-friendly policy See policy
  • Hotel staff were very accommodating and friendly
  • For 89%, the rooms looked old
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