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Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates

Charleston Hotels/Motels & Accommodations

Super 8 by Wyndham Charleston/Sikeston East MO
+1-888-389-4121
310 South Story, Charleston, MO 63834
  • Two star Highway hotel
  • 60 sleeping rooms in hotel
From$42
Average 3.5 /5 Recent Reviews Call BookMore Details
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Quality Inn Charleston - Sikeston
+1-888-675-2083
102 Drake St., Charleston, MO 63834
  • Economical Highway property
  • Comp. Breakfast
From$59
Average 3.0 /5 Read Reviews Call BookMore Details
Motel 6 Sikeston Mo : 110 South Interstate Dr.
+1-800-716-8490
110 South Interstate Dr., SIKESTON, MO 63801 ~11.02 miles west of Charleston
  • Economical property
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Best Western Plus Sikeston
+1-800-805-5223
120 South Interstate Dr., Sikeston, MO 63801 ~11.05 miles west of Charleston
  • Two-star Highway property
  • Free complimentary breakfast
From$43
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston in Sikeston
+1-888-965-1860
220 South Interstate Dr., Sikeston, MO 63801 ~11.09 miles west of Charleston
  • Economy hotel
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn Cairo I-57 in Cairo
+1-888-788-5576
13201 Kessler Rd., Cairo, IL 62914 ~11.20 miles northeast of Charleston
  • 3-star Highway hotel
  • 2 floors in hotel
Super 8 by Wyndham Sikeston/Miner Area - Sikeston
+1-888-897-9207
2609 East Malone, Sikeston, MO 63801 ~11.36 miles west of Charleston
  • Cheap Convention Center property
  • Comp. Breakfast
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) : 100 Matthews Lane
+1-888-311-4278
100 Matthews Lane, Sikeston, MO 63801 ~11.37 miles west of Charleston
  • Three Star Highway hotel
  • Free breakfast available
From$80
Very Good 4.0 /5 Read Reviews Call BookMore Details
Comfort Inn - Sikeston
+1-888-469-4795
109 Matthews Lane, Sikeston, MO 63801 ~11.40 miles west of Charleston
  • Midscale Highway hotel
  • Check-in: 11:00
From$85
Average 3.0 /5 Review Score Call BookMore Details
Drury Inn & Suites Sikeston - Sikeston
+1-888-734-9421
2608 East Malone Ave., Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Midscale Highway hotel
  • Fitness + Health Center
From$104
Very Good 4.5 /5 Review Score Call BookMore Details
Pear Tree Inn Sikeston
+1-888-841-5292
2602 East Malone, Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Mid-scale Suburban property
  • 80 sleeping rooms in hotel
From$80
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn Sikeston
+1-888-455-5160
1240 Commerce Dr., Sikeston, MO 63801 ~14.31 miles west of Charleston
  • Three Star Rural property
  • Fitness + Health Center
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel in Sikeston
+1-888-965-8297
115 Hospitality Dr., Sikeston, MO 63801 ~14.33 miles west of Charleston
  • Three Star Rural property
  • Check-in time: 3:00pm
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds : 128 Cheekwood Lane
+1-888-906-6358
128 Cheekwood Lane, Ullin, IL 62992 ~25.98 miles north of Charleston
  • Two-star property
  • Complimentary breakfast is offered
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown in Cape Girardeau
+1-888-749-6785
400 Broadway St., Cape Girardeau, MO 63701 ~28.56 miles north of Charleston
  • Midscale Downtown hotel
  • 78 sleeping rooms in hotel
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
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Candlewood Suites Cape Girardeau by IHG
+1-888-878-9982
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~28.61 miles northwest of Charleston
  • 2 star Highway hotel
  • 85 rooms in hotel
From$69
Very Good 4.0 /5 Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East
+1-888-389-4485
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 ~29.33 miles northwest of Charleston
  • Affordable Highway hotel
  • Free breakfast available
From$80
Excellent 5.0 /5 Reviews Call BookMore Details
Victorian Inn & Suites in Cape Girardeau
+1-888-389-4121
3256 William St., Cape Girardeau, MO 63703 ~29.40 miles northwest of Charleston
  • Affordable Golf Course property
  • Comp. Breakfast
From$79
Average 3.0 /5 Read Reviews Call BookMore Details
Auburn Place Hotel & Suites - Cape Girardeau
+1-888-675-2083
3265 Williams St., Cape Girardeau, MO 63702 ~29.41 miles northwest of Charleston
  • Three Star Highway hotel
  • Comp. Breakfast
From$58
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 - Cape Girardeau
+1-800-716-8490
3253 William St., Cape Girardeau, MO 63701 ~29.43 miles northwest of Charleston
  • Mid-scale property
  • Check-in: 11:00
From$80
Very Good 4.5 /5 Review Score Call BookMore Details
Fairfield Inn & Suites Cape Girardeau
+1-800-805-5223
433 Cape West Crossing, Cape Girardeay, MO 63703 ~29.46 miles northwest of Charleston
  • Mid-scale property
  • Hotel has 22 suites
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West
+1-888-965-1860
103 Cape West Pkwy., Cape Girardeau, MO 63701 ~29.49 miles northwest of Charleston
  • 2 star hotel
  • 2 suites in property
From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center
+1-888-788-5576
3248 William St., Cape Girardeau, MO 63701 ~29.50 miles northwest of Charleston
  • 2-star Highway property
  • Complimentary breakfast is offered
From$66
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Drury Suites Cape Girardeau : 3303 Campster Dr.
+1-888-897-9207
3303 Campster Dr., Cape Girardeau, MO 63701 ~29.60 miles northwest of Charleston
  • 3 star Highway property
  • 86 rooms in property
From$85
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau
+1-888-311-4278
3351 Percy Dr., Cape Girardeau, MO 63701 ~29.76 miles northwest of Charleston
  • Affordable hotel
  • 8 floors in property
From$59
Average 3.0 /5 Reviews Call BookMore Details
Drury Lodge : 104 South Vantage Dr.
+1-888-469-4795
104 South Vantage Dr., Cape Girardeau, MO 63701 ~29.77 miles northwest of Charleston
  • Mid-scale Highway property
  • Free breakfast
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Travel Inn - Marston
+1-888-734-9421
301 Route Ad, Marston, MO 63866 ~31.28 miles southwest of Charleston
  • Inexpensive Highway property
  • Check in time: 3:00 PM
Travel Inn - Martson
+1-888-841-5292
301 State Highway Ad, Martson, MO 63866 ~31.46 miles southwest of Charleston
  • Two star property
Red Roof Inn Marston
+1-888-455-5160
501 South Outer Rd., Marston, MO 63866 ~31.61 miles southwest of Charleston
  • Two-star hotel
  • 2 floors in property
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn in Cape Girardeau
+1-888-965-8297
2011 North Kingshighway St., Cape Girardeau, MO 63701 Website ~31.73 miles northwest of Charleston
  • Two-star property
  • Hotel has an eco-friendly policy Read more
From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
TRU by Hilton Cape Girardeau
+1-888-906-6358
2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 ~32.92 miles northwest of Charleston
  • Affordable Highway property
  • Fitness / Gym is on-site
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau
+1-888-749-6785
3003 South Old Orchard Rd., Jackson, MO 63755 ~33.46 miles northwest of Charleston
  • Three Star Highway hotel
  • 9 suites in hotel
From$85
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Comfort Suites in Jackson
+1-888-878-9982
2904 Old Orchard Rd., Jackson, MO 63755 ~33.57 miles northwest of Charleston
  • 3-star Highway property
  • Check-in: 3:00 PM
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Residence Inn by Marriott Paducah - Paducah
+1-888-389-4485
3900 Coleman Crossing Circle, Paducah, KY 42001 ~34.97 miles east of Charleston
  • Mid-scale Suburban property
  • 2 conference rooms in property
From$89
Very Good 4.0 /5 Reviews Call BookMore Details
Pear Tree Inn Paducah - Paducah
+1-888-389-4121
5006 Hinkleville Rd., Paducah, KY 42001 ~35.47 miles east of Charleston
  • Two-star Suburban hotel
  • Check in: 3:00 PM
From$55
Very Good 4.0 /5 Review Score Call BookMore Details
Econo Lodge Dexter
+1-888-675-2083
913 Outer Rd., Dexter, MO 63841 ~36.12 miles west of Charleston
  • 2-star property
  • Check in: 11:00
From$60
Average 3.0 /5 Review Score Call BookMore Details
Harrah's Metropolis Hotel & Casino - Metropolis
+1-800-716-8490
100 East Front St., Metropolis, IL 62960 ~36.52 miles east of Charleston
  • 4-star property
  • 252 sleeping rooms in hotel
From$160
Very Good 4.0 /5 Read Reviews Call BookMore Details
Baymont by Wyndham Metropolis - Metropolis
+1-800-805-5223
203 East Front St., Metropolis, IL 62960 ~36.55 miles east of Charleston
  • Two-star Riverfront hotel
  • Hotel has 8 suites
From$45
Average 3.0 /5 Recent Reviews Call BookMore Details
Sleep Inn & Mainstay Suites
+1-888-965-1860
1111 Blue Heron Lane, Union City, TN 38261 ~36.64 miles southeast of Charleston
  • Economy Rural property
  • Check-in: 15:00
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Travelodge by Wyndham Dexter in Dexter
+1-888-788-5576
1608 West Business U.s. 60, Dexter, MO 63841 ~36.87 miles west of Charleston
  • 3 star property
From$67
Very Good 4.0 /5 Read Reviews Call BookMore Details
 Econo Lodge Paducah West I-24
+1-888-897-9207
5120 Hinkleville Rd., Paducah, KY 42001 ~37.23 miles east of Charleston
  • 2 star Airport property
  • Check-in time: 15:00pm
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Drury Suites Paducah : 2930 James Sanders Blvd.
+1-888-311-4278
2930 James Sanders Blvd., Paducah, KY 42001 ~37.34 miles east of Charleston
  • Midscale Suburban hotel
  • 6 floors in property
From$99
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Quality Suites Paducah I-24 in Paducah
+1-888-469-4795
2880 James Sanders Blvd., Paducah, KY 42001 Website ~37.41 miles east of Charleston
  • Economical Highway property
  • Hotel has an eco-friendly policy See policy
From$60
Average 3.0 /5 Review Score Call BookMore Details
Sleep Inn Union City
+1-888-734-9421
1111b Blue Heron Lane, Union City, TN 38261 ~37.44 miles southeast of Charleston
  • 2-star Rural hotel
  • Hotel has 9 suites
From$78
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites near Six Flags : 960 West Pointe Court
+1-888-841-5292
960 West Pointe Court, Lithia Springs, GA 30122 Website ~37.46 miles east of Charleston
  • Three Star Downtown property
  • Free breakfast available
From$70
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Country Inn & Suites by Radisson, Paducah, KY : 145 Mcbride Lane
+1-888-455-5160
145 Mcbride Lane, Paducah, KY 42001 ~37.46 miles east of Charleston
  • 3-star Highway property
  • 60 sleeping rooms in hotel
From$49
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Paducah
+1-888-965-8297
5300 Old Cairo Rd., Paducah, KY 42001 ~37.50 miles east of Charleston
  • Three Star property
  • Check-in time: 15:00
Hotel 7 Inn Paducah
+1-888-906-6358
5001 Hinkleville Rd., Paducah, KY 42001 ~37.51 miles east of Charleston
  • 2 star property
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Econo Lodge
+1-888-749-6785
1415 East 5th St., Metropolis, IL 62960 ~37.60 miles east of Charleston
  • Economy property
  • 45 rooms in hotel
From$60
Not Good 1.0 /5 Review Score Call BookMore Details
Mainstay Suites in Union City
+1-888-878-9982
1111a Blue Heron Lane, Union City, TN 38261 ~37.65 miles southeast of Charleston
  • Low-priced Rural property
  • Hotel has 37 suites
From$85
Average 3.0 /5 Review Score Call BookMore Details

Next: See My Charleston Hotels with Pricing

Graph of Charleston, MO Hotel Prices for Next 20 Days

Rates shown are nightly rates before taxes and do not necessarily reflect all Charleston, MO discounts available. The chart reflects the cheapest Charleston hotel for each day and each star rating category.

FAQs about hotels in Charleston

What are the most favored hotels in Charleston?

Hampton Inn Cape Girardeau I 55 East, Drury Inn & Suites Sikeston and Auburn Place Hotel & Suites are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels in Charleston?

Harrah's Metropolis Hotel & Casino, Quality Inn Cairo I-57 and Travel Inn & Suites - Sikeston are the top 3 luxury hotels near Charleston city center.

What hotels are closest to the city center of Charleston?

Super 8 by Wyndham Charleston, Quality Inn Charleston - Sikeston, and Motel 6 Sikeston Mo are the properties closest to Charleston city center.

How much does a cheap hotel in Charleston cost per night?

In the last year, a 2 star hotel in Charleston can be as cheap as $69.99 per night. (based on HotelPlanner prices)

How much does a 3 star hotel in Charleston cost per night?

In the last year, the average 3 star hotel in Charleston has been $54.99 per night. (based on HotelPlanner prices)

What are the best independent hotels in Charleston?

Auburn Place Hotel & Suites, Drury Suites Cape Girardeau and Travel Inn & Suites - Sikeston are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Charleston?

Courtyard by Marriott Cape Girardeau Downtown, Residence Inn by Marriott Paducah and Fairfield Inn & Suites Cape Girardeau are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels in Charleston?

Quality Inn, Sleep Inn Union City and Comfort Inn & Suites near Six Flags are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Charleston?

Holiday Inn Express & Suites Cape Girardeau I 55, Candlewood Suites Cape Girardeau by IHG and Holiday Inn Express & Suites Sikeston An Ihg Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Recent traveler reviews of Charleston, MO

Below are reviews of the city of Charleston, MO from an actual visitor's perspective.

"Easily Accessible"
Score 5.0 / 5

Easily accessible.

Mamon T., from 07-Dec-2023
The average traveler rating of the city of Charleston, MO shown above is 5.0 out of 5 based on 1 reviews
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