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Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates

Charleston Hotels/Accommodations

Super 8 310 South Story, Charleston, MO 63834
  • 2-star Highway hotel
Quality Inn - Charleston 102 Drake St., Charleston, MO 63834
  • 2-star Highway hotel
  • 2 floors in property
  • Vibe is not too good
  • Tasty breakfast
Best Western Plus Sikeston 120 South Interstate Dr., Sikeston, MO 63801 ~11.00 miles west of Charleston
  • Two star Highway hotel
  • 55 rooms in hotel
Americas Best Value Inn & Suites : 220 South Interstate Dr. 220 South Interstate Dr., Sikeston, MO 63801 ~11.09 miles west of Charleston
  • Economy hotel
  • 60 rooms in hotel
From$49
Very Good 4.0 /5Read Reviews CallBookMore Details
Quality Inn - Cairo 13201 Kessler Rd., Cairo, IL 62914 ~11.20 miles northeast of Charleston
  • Three Star hotel
  • Hotel has 38 rooms
Country Hearth Inn & Suites Sikeston 100 Matthews Lane, Sikeston, MO 63801 ~11.36 miles west of Charleston
  • 2-star Highway hotel
  • 40 sleeping rooms in hotel
Comfort Inn & Suites - Sikeston
+1-888-283-3404
109 Matthews Lane, Sikeston, MO 63801 ~11.37 miles west of Charleston
  • Three Star Highway hotel
  • 17 suites in property
  • Good Hotel
  • Breakfast can be improved
Super 8 - Sikeston
+1-800-997-5149
2609 East Malone Ave., Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Two-star Convention Center hotel
  • 62 rooms in hotel
Drury Inn & Suites Sikeston in Sikeston 2608 East Malone Ave., Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Midscale Highway property
  • Hotel has 14 suites
  • Most guests were happy with the price
  • Night stay for free
From$85
Very Good 4.5 /5Review Score CallBookMore Details
Pear Tree Inn Sikeston 2602 East Malone, Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Mid-scale Suburban hotel
  • Hotel has an eco-friendly policy Learn more
  • Great location
  • Food is to die for
Holiday Inn Express & Suites Sikeston in Sikeston 115 Hospitality Dr., Sikeston, MO 63801 ~14.33 miles west of Charleston
  • Cheap property
  • Gym / Fitness Center Available
From$75
Very Good 4.5 /5Read Reviews CallBookMore Details
Days Inn Sikeston : 1330 South Main St.
+1-888-690-5247
1330 South Main St., Sikeston, MO 63801 ~14.44 miles west of Charleston
  • Two star hotel
  • Check in time: 11:00 AM
Candlewood Suites Cape Girardeau
+1-888-305-3366
485 South Mt. Auburn Rd., Cape Girardeau, MO 63703 ~28.56 miles northwest of Charleston
  • Low-priced hotel
  • 85 sleeping rooms in hotel
Candlewood Suites Cape Girardeau 485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~28.61 miles northwest of Charleston
  • Cheap Highway property
  • Hotel has 85 rooms
Victorian Inn & Suites in Cape Girardeau
+1-888-283-3404
3256 William St., Cape Girardeau, MO 63703 ~29.40 miles northwest of Charleston
  • Mid-scale Golf Course property
  • 2 floors in hotel
Auburn Place Hotel & Suites - Cape Girardeau 3265 Williams St., Cape Girardeau, MO 63702 ~29.41 miles northwest of Charleston
  • 3 star Highway hotel
  • 5 suites in hotel
  • Good fitness area
  • Common areas wonderful
Holiday Inn Express & Suites Cape Girardeau I 55
+1-888-690-5281
3253 William St., Cape Girardeau, MO 63701 ~29.43 miles northwest of Charleston
  • Low-priced hotel
  • Check in time: 11:00
Pear Tree Inn Cape Girardeau Medical Center - Cape Girardeau 3248 William St., Cape Girardeau, MO 63701 ~29.50 miles northwest of Charleston
  • 2 star Highway property
  • 78 sleeping rooms in hotel
  • Staff was very nice and knowledgeable
  • Good accessibility by car
Drury Suites Cape Girardeau 3303 Campster Dr., Cape Girardeau, MO 63701 ~29.60 miles northwest of Charleston
  • Midscale Highway property
  • 86 sleeping rooms in hotel
  • Delicious food
  • Tasty breakfast
From$119
Very Good 4.5 /5Recent Reviews CallBookMore Details
Drury Lodge Cape Girardeau : 104 South Vantage Dr. 104 South Vantage Dr., Cape Girardeau, MO 63701 ~29.76 miles northwest of Charleston
  • Mid-scale Highway property
  • 139 rooms in property
  • Most guests were happy with the price of the breakfast
  • Plenty of square footage
Travelodge 301 Route Ad, Marston, MO 63866 ~31.28 miles southwest of Charleston
  • Economical Highway hotel
  • Free breakfast
Super 8 Cape Girardeau in Cape Girardeau 2011 North Kingshighway, Cape Girardeau, MO 63701 ~31.73 miles northwest of Charleston
  • 2-star property
Comfort Suites Jackson / Cape Girardeau - Jackson 2904 Old Orchard Rd., Jackson, MO 63755 ~33.57 miles northwest of Charleston
  • Affordable Highway hotel
  • 3 floors in hotel
  • Tasty breakfast
  • New hair dryer
From$65
Very Good 4.0 /5Review Score CallBookMore Details
Residence Inn - Paducah 3900 Coleman Crossing Circle, Paducah, KY 42001 ~34.97 miles east of Charleston
  • 3-star Suburban hotel
  • Fitness center on property
  • World class service
  • Decent breakfast
Pear Tree Inn Paducah : 5006 Hinkleville Rd. 5006 Hinkleville Rd., Paducah, KY 42001 ~35.47 miles east of Charleston
  • Two-star Suburban property
  • Check-in: 3:00 PM
  • Rooms in need of an update
  • Plenty of parking
From$62
Very Good 4.0 /5Reviews CallBookMore Details
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