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Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.

Cairo Hotels, Motels & Accommodations

Eagle Inn : 2811 East Marshall St.
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863
2811 East Marshall St., Charleston, MO 63834 ~9.29 miles southwest of Cairo
  • 2-star hotel
  • Check-in: 3:00PM
More PhotosImage of Eagle Inn
From$44
Average 3.5 /5Reviews Call
Super 8
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863 Front Desk: 15736832125
310 South Story, Charleston, MO 63834 ~10.14 miles southwest of Cairo
  • Low-priced Highway property
  • Free breakfast
More Photos Exterior of Super 8
From$49
Average 3.5 /5Latest Reviews Call
Quality Inn : 102 Drake St.
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 15736834200
102 Drake St., Charleston, MO 63834 ~11.82 miles southwest of Cairo
  • Economy Highway property
  • 9 suites in hotel
More Photos Image of Quality Inn
From$59
Average 3.5 /5Latest Reviews Call
Best Western Plus Sikeston
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 15734819500
120 South Interstate Dr., Sikeston, MO 63801 ~20.97 miles west of Cairo
  • Two-star Highway hotel
  • Hotel has a green policy Learn more
More Photos Image of Best Western Plus Sikeston
From$89
Very Good 4.5 /5Read Reviews Call
Americas Best Value Inn & Suites in Sikeston
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 15734719700
220 South Interstate Dr., Sikeston, MO 63801 ~21.11 miles west of Cairo
  • 2 star hotel
  • Hotel has 60 suites
More Photos hotel room
From$64
Average 3.5 /5Reviews Call
Country Hearth Inn & Suites Sikeston in Sikeston
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 15734724400
100 Matthews Lane, Sikeston, MO 63801 ~21.35 miles west of Cairo
  • 2-star Highway property
  • Free complimentary breakfast
More Photos Exterior of Country Hearth Inn & Suites Sikeston
From$50
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Comfort Inn & Suites
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863
109 Matthews Lane, Sikeston, MO 63801 ~21.36 miles west of Cairo
  • Mid-scale Highway property
  • Free complimentary breakfast
More Photos Photo of Comfort Inn & Suites
From$80
Average 3.5 /5Hotel Reviews Call
Drury Inn & Suites Sikeston
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 18004361169
2608 East Malone Ave., Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Mid-scale Highway hotel
  • Hotel has 5 floors
More Photos Image of Drury Inn & Suites Sikeston
From$109
Very Good 4.5 /5Review Score Call
Super 8 in Sikeston
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863
2609 East Malone Ave., Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Two star Convention Center property
  • 62 sleeping rooms in hotel
More Photos Photo of Super 8
From$44
Average 3.0 /5Recent Reviews Call
Pear Tree Inn Sikeston
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 18003250720
2602 East Malone, Sikeston, MO 63801 ~21.42 miles west of Cairo
  • 3 star Suburban property
  • 2 suites in hotel
More Photos Photo of Pear Tree Inn Sikeston
From$69
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Residence Inn in Paducah
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 12704443966
3900 Coleman Crossing Circle, Paducah, KY 42001 ~25.70 miles east of Cairo
  • 3 star Suburban hotel
  • Check-in time: 3:00PM
More Photos Image of Residence Inn
From$90
Very Good 4.5 /5Latest Reviews Call
Pear Tree Inn Paducah : 5006 Hinkleville Rd.
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 18003250720
5006 Hinkleville Rd., Paducah, KY 42001 ~25.80 miles east of Cairo
  • Economical Suburban property
  • Hotel has 2 floors
More Photos Exterior of Pear Tree Inn Paducah
From$62
Very Good 4.0 /5Reviews Call
Baymont Inn & Suites Metropolis Il
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 16185245678
203 East Front St., Metropolis, IL 62960 ~26.33 miles east of Cairo
  • Cheap Riverfront property
  • Gym / Fitness Center Available
More Photos Exterior of Baymont Inn & Suites Metropolis Il
From$35
Average 3.5 /5Read Reviews Call
Drury Suites Paducah in Paducah
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863 Front Desk: 18004361169
2930 James Sanders Blvd., Paducah, KY 42001 ~27.73 miles east of Cairo
  • 3 star Suburban hotel
  • Free complimentary breakfast
More Photos Photo of Drury Suites Paducah
From$114
Very Good 4.5 /5Latest Reviews Call
Quality Suites
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 12704422080
2880 James Sanders Blvd., Paducah, KY 42001 ~27.76 miles east of Cairo
  • 3 star Highway property
  • Hotel has 59 suites
More Photos Photo of Quality Suites
From$60
Very Good 4.0 /5Read Reviews Call
Country Inn & Suites
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863
145 Mcbride Lane, Paducah, KY 42001 ~27.83 miles east of Cairo
  • Midscale Highway property
  • Check in: 4pm
More Photos Image of Country Inn & Suites
From$65
Very Good 4.0 /5Hotel Reviews Call
Thrifty Inn in Paducah
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 18004459410
5004 Hinkleville Rd., Paducah, KY 42001 ~27.85 miles east of Cairo
  • 2-star property
  • 4 floors in hotel
More Photos Image of Thrifty Inn
From$75
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La Quinta Inn & Suites
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 12704434800
3960 Coleman Crossing Circle, Paducah, KY 42001 ~27.93 miles east of Cairo
  • Affordable Highway hotel
  • 77 rooms in property
More Photos Image of La Quinta Inn & Suites
From$85
Excellent 5.0 /5Review Score Call
Candlewood Suites in Paducah
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 12704423969
3940 Coleman Crossing Circle, Paducah, KY 42001 ~27.94 miles east of Cairo
  • Two star Rural property
  • Check in time: 3:00pm
More Photos Image of Candlewood Suites
From$55
Very Good 4.0 /5Reviews Call
Comfort Inn Paducah
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 12704424191
5135 Old Cairo Rd., Paducah, KY 42001 ~28.01 miles east of Cairo
  • Low priced hotel
  • 3 floors in property
More Photos Exterior of Comfort Inn Paducah
From$70
Very Good 4.5 /5Review Score Call
Econo Lodge Paducah in Paducah
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863
5106 Old Cairo Rd., Paducah, KY 42001 ~28.01 miles east of Cairo
  • 2 star hotel
More Photos hotel room
From$75
Very Good 4.0 /5Guest Reviews Call
Fairfield Inn & Suites - Paducah
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 12707098003
3950 Coleman Crossing Circle, Paducah, KY 42001 ~28.03 miles east of Cairo
  • 3 star Rural hotel
  • Access to gym on-site
More Photos Image of Fairfield Inn & Suites
From$80
Very Good 4.5 /5Guest Reviews Call
Hampton Inn & Suites - Paducah
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863
3901 Coleman Crossing Circle, Paducah, KY 42001 ~28.08 miles east of Cairo
  • 3 star Highway property
  • 32 suites in property
More Photos Photo of Hampton Inn & Suites
From$109
Very Good 4.5 /5Recent Reviews Call
Super 8 Metropolis : 2055 East 5th St.
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863
2055 East 5th St., Metropolis, IL 62960 ~28.13 miles east of Cairo
  • Low priced Highway hotel
  • 2 floors in hotel
More Photos Image of Super 8 Metropolis
From$48
Average 3.5 /5Latest Reviews Call
Holiday Inn Express - Paducah
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 12704428874
3994 Hinkleville Rd., Paducah, KY 42001 ~28.13 miles east of Cairo
  • 2 star Highway property
  • Check-in: 3:00 PM
More Photos Photo of Holiday Inn Express
From$95
Very Good 4.5 /5Recent Reviews Call
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