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Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.

Cairo Hotels, Motels & Accommodations

Quality Inn
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-618-734-0215
13201 Kessler Rd., Cairo, IL 62914
  • Mid-scale property
  • 38 rooms in property
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From$80
Very Good 4.0 /5Guest Reviews CallBookMore Details
Super 8
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 1-573-683-2125
310 South Story, Charleston, MO 63834 ~10.14 miles southwest of Cairo
  • 2 star Highway property
  • Free breakfast
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From$49
Average 3.5 /5Latest Reviews CallBookMore Details
Quality Inn
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 1-573-683-4200
102 Drake St., Charleston, MO 63834 ~11.90 miles southwest of Cairo
  • 2 star Highway hotel
  • 2 floors in property
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From$67
Average 3.5 /5Hotel Reviews CallBookMore Details
Americas Best Value Inn
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 1-618-845-3700
128 Cheekwood Lane, Ullin, IL 62992 ~17.90 miles north of Cairo
  • Low Cost hotel
More Photos hotel room
From$60
Very Good 4.0 /5Read Reviews CallBookMore Details
Best Western Plus Sikeston
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863 Front Desk: 1-573-481-9500
120 South Interstate Dr., Sikeston, MO 63801 ~21.04 miles west of Cairo
  • Low priced Highway hotel
  • Hotel has 2 floors
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From$69
Very Good 4.5 /5Hotel Reviews CallBookMore Details
Americas Best Value Inn & Suites : 220 South Interstate Dr.
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863 Front Desk: 1-573-471-9700
220 South Interstate Dr., Sikeston, MO 63801 ~21.11 miles west of Cairo
  • Cheap property
  • 60 suites in hotel
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From$49
Average 3.5 /5Reviews CallBookMore Details
Country Hearth Inn & Suites Sikeston : 100 Matthews Lane
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 1-573-472-4400
100 Matthews Lane, Sikeston, MO 63801 ~21.35 miles west of Cairo
  • Low Cost Highway property
  • Comp. Breakfast
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From$50
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Comfort Inn & Suites
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863
109 Matthews Lane, Sikeston, MO 63801 ~21.36 miles west of Cairo
  • 3 star Highway property
  • Gym / Fitness Center Available
  • Nice indoor pool and fitness room
  • Towels available
More Photos Photo of Comfort Inn & Suites
From$80
Average 3.5 /5Latest Reviews CallBookMore Details
Drury Inn & Suites Sikeston in Sikeston
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 1-800-436-1126
2608 East Malone Ave., Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Mid-scale Highway property
  • 154 rooms in property
  • Awesome vibe and great food
  • Easily accessible by car
More Photos Exterior of Drury Inn & Suites Sikeston
From$85
Very Good 4.5 /5Review Score CallBookMore Details
Super 8 - Sikeston
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863
2609 East Malone Ave., Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Low Cost Convention Center property
  • 62 sleeping rooms in hotel
More Photos Image of Super 8
From$44
Average 3.0 /5Read Reviews CallBookMore Details
Pear Tree Inn Sikeston - Sikeston
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 1-800-325-0720
2602 East Malone, Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Three Star Suburban hotel
  • Free comp. breakfast
  • Amenities are good
  • Alcoholic drinks are not the best
More Photos Image of Pear Tree Inn Sikeston
From$75
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Holiday Inn Express & Suites Sikeston in Sikeston
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863 Front Desk: 1-573-475-9522
115 Hospitality Dr., Sikeston, MO 63801 ~24.54 miles west of Cairo
  • Economy hotel
  • 73 rooms in hotel
More Photos Photo of Holiday Inn Express & Suites Sikeston
From$60
Very Good 4.5 /5Recent Reviews CallBookMore Details
Days Inn Sikeston : 1330 South Main St.
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863
1330 South Main St., Sikeston, MO 63801 ~24.66 miles west of Cairo
  • Low Cost hotel
  • Check-in time: 11:00 AM
More Photos Photo of Days Inn Sikeston
From$60
Poor 2.0 /5Recent Reviews CallBookMore Details
Residence Inn
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 1-270-444-3966
3900 Coleman Crossing Circle, Paducah, KY 42001 ~25.70 miles east of Cairo
  • Three Star Suburban hotel
  • Check in: 3:00PM
  • Best hotel breakfast
  • All guests said rooms were clean
More Photos Photo of Residence Inn
From$89
Very Good 4.5 /5Latest Reviews CallBookMore Details
Pear Tree Inn Paducah : 5006 Hinkleville Rd.
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-800-436-1126
5006 Hinkleville Rd., Paducah, KY 42001 ~25.80 miles east of Cairo
  • Cheap Suburban property
  • Free complimentary breakfast
  • Room that included
  • About half of guests thought the building was acceptable
More Photos Exterior of Pear Tree Inn Paducah
From$62
Very Good 4.0 /5Read Reviews CallBookMore Details
Baymont Inn & Suites Metropolis Il
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 1-618-524-5678
203 East Front St., Metropolis, IL 62960 ~26.33 miles east of Cairo
  • Cheap Riverfront hotel
  • Gym is available on property
  • Average beds
  • Inexpensive steak
More Photos Photo of Baymont Inn & Suites Metropolis Il
From$35
Average 3.5 /5Review Score CallBookMore Details
Baymont Inn & Suites Paducah : 5300 Old Cairo Rd.
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 1-270-443-4343
5300 Old Cairo Rd., Paducah, KY 42001 ~27.67 miles east of Cairo
  • 3-star hotel
  • 74 rooms in property
More Photos Image of Baymont Inn & Suites Paducah
From$40
Very Good 4.0 /5Read Reviews CallBookMore Details
Drury Suites Paducah
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 1-800-436-1126
2930 James Sanders Blvd., Paducah, KY 42001 ~27.73 miles east of Cairo
  • Three Star Suburban hotel
  • Hotel has a green policy Learn more
  • Rooms are great
  • Most guests thought the service was very professional
More Photos Image of Drury Suites Paducah
From$90
Very Good 4.5 /5Hotel Reviews CallBookMore Details
Quality Suites
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863 Front Desk: 1-270-442-2080
2880 James Sanders Blvd., Paducah, KY 42001 ~27.76 miles east of Cairo
  • Mid-scale Highway property
  • Gym / Fitness Center Available
More Photos Photo of Quality Suites
From$70
Very Good 4.0 /5Recent Reviews CallBookMore Details
Country Inn & Suites - Paducah
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863 Front Desk: 1-270-442-2201
145 Mcbride Lane, Paducah, KY 42001 ~27.83 miles east of Cairo
  • Mid-scale Highway property
  • Fitness center on property
More Photos Exterior of Country Inn & Suites
From$65
Very Good 4.0 /5Review Score CallBookMore Details
Country Inn & Suites Lithia Springs
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 1-800-456-4000
960 West Pointe Court, Lithia Springs, GA 30122 ~27.83 miles east of Cairo
  • Affordable Rural property
  • Hotel has 55 suites
More Photos Photo of Country Inn & Suites Lithia Springs
From$70
Poor 2.5 /5Review Score CallBookMore Details
Super 8 Paducah Ky in Paducah
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-270-442-3334
5001 Hinkleville Rd., Paducah, KY 42001 ~27.85 miles east of Cairo
  • Cheap property
  • Check in: 11:00 AM
More Photos Exterior of Super 8 Paducah Ky
From$60
Average 3.5 /5Guest Reviews CallBookMore Details
Thrifty Inn
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 1-800-445-9410
5004 Hinkleville Rd., Paducah, KY 42001 ~27.85 miles east of Cairo
  • 2-star property
  • Hotel has 124 rooms
  • Cleaned carpet
  • Furniture needs more attention
More Photos Photo of Thrifty Inn
From$60
CallBookMore Details
La Quinta Inn & Suites
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 1-270-443-4800
3960 Coleman Crossing Circle, Paducah, KY 42001 ~27.93 miles east of Cairo
  • Affordable Highway hotel
  • Hotel has 2 meeting rooms
More Photos Exterior of La Quinta Inn & Suites
From$89
Excellent 5.0 /5Review Score CallBookMore Details
Candlewood Suites - Paducah
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 1-270-442-3969
3940 Coleman Crossing Circle, Paducah, KY 42001 ~27.94 miles east of Cairo
  • Economical Rural hotel
  • Check-in time: 3:00pm
More Photos Photo of Candlewood Suites
From$60
Very Good 4.0 /5Recent Reviews CallBookMore Details
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