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Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.

Cairo Hotels/Accommodations

Quality Inn Cairo I-57 in Cairo
+1-888-389-4121
13201 Kessler Rd., Cairo, IL 62914
  • Mid-scale Highway property
  • Check-in time: 3 pm
  • Bed was comfortable
  • Disappointing food
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Super 8 by Wyndham Charleston MO in Charleston
+1-888-675-2083
310 South Story, Charleston, MO 63834 ~10.14 miles southwest of Cairo
  • 2-star Highway hotel
  • Hotel has 60 rooms
Quality Inn : 102 Drake St.
+1-800-716-8490
102 Drake St., Charleston, MO 63834 ~11.90 miles southwest of Cairo
  • Cheap Highway property
  • Check in time: 3:00PM
From$59
Average 3.0 /5Reviews CallBookMore Details
Americas Best Value Inn Ullin Mounds
+1-800-805-5223
128 Cheekwood Lane, Ullin, IL 62992 ~17.90 miles north of Cairo
  • Cheap hotel
  • Check-in: 15:00
From$60
Very Good 4.0 /5Reviews CallBookMore Details
Motel 6 Sikeston Mo #4328 in SIKESTON
+1-888-965-1860
110 South Interstate Dr., SIKESTON, MISSOURI 63801 ~21.01 miles west of Cairo
  • Low priced property
Best Western Plus Sikeston : 120 South Interstate Dr.
+1-888-788-5576
120 South Interstate Dr., Sikeston, MO 63801 ~21.04 miles west of Cairo
  • Cheap Highway property
  • Hotel has an eco-friendly policy Learn more
Days Inn and Suites by Wyndham Sikeston
+1-888-897-9207
220 South Interstate Dr., Sikeston, MO 63801 ~21.11 miles west of Cairo
  • Two-star hotel
  • Check-in time: 03:00 PM
Drury Inn & Suites Sikeston - Sikeston
+1-888-311-4278
2608 East Malone Ave., Sikeston, MO 63801 ~21.28 miles west of Cairo
  • Three Star Highway hotel
  • Gym is available on property
From$80
Average 3.0 /5Reviews CallBookMore Details
Travel Inn & Suites
+1-888-469-4795
100 Matthews Lane, Sikeston, MO 63801 ~21.35 miles west of Cairo
  • Affordable Highway property
  • 40 rooms in hotel
  • Average hotel building
  • Breakfast can be improved
Super 8 by Wyndham Sikeston / Miner Area - Sikeston
+1-888-734-9421
2609 East Malone, Sikeston, MO 63801 ~21.37 miles west of Cairo
  • Economical Convention Center hotel
  • Check-in time: 01:00
Comfort Inn : 109 Matthews Lane
+1-888-841-5292
109 Matthews Lane, Sikeston, MO 63801 ~21.39 miles west of Cairo
  • Three Star Highway property
  • Check-in time: 11:00
Pear Tree Inn Sikeston
+1-888-455-5160
2602 East Malone, Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Midscale Suburban hotel
  • 4 floors in hotel
  • Desk clerk was very friendly and courteous
  • Best value for money
Holiday Inn Express Sikeston in Sikeston
+1-888-965-8297
115 Hospitality Dr., Sikeston, MO 63801 ~24.55 miles west of Cairo
  • Mid-scale Rural property
  • Check-in: 15:00
From$94
Very Good 4.0 /5Reviews CallBookMore Details
Hampton Inn Sikeston - Sikeston
+1-888-906-6358
1240 Commerce Dr., Sikeston, MO 63801 ~24.92 miles west of Cairo
  • Three Star property
  • Gym is available on property
Residence Inn
+1-888-749-6785
3900 Coleman Crossing Circle, Paducah, KY 42001 ~25.70 miles east of Cairo
  • Three Star Suburban property
  • 74 suites in property
  • Excellent amenities
  • Clean rooms
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Pear Tree Inn Paducah : 5006 Hinkleville Rd.
+1-888-878-9982
5006 Hinkleville Rd., Paducah, KY 42001 ~25.80 miles east of Cairo
  • Economical Suburban hotel
  • Has environment-friendly policy Learn more
  • Rooms in need of an update
  • Hotel staff were very accommodating and friendly
Harrah's Metropolis Hotel & Casino in Metropolis
+1-888-389-4485
100 East Front St., Metropolis, IL 62960 ~26.30 miles east of Cairo
  • High end property
  • Check-in: 16:00
From$160
Very Good 4.0 /5Recent Reviews CallBookMore Details
Baymont by Wyndham Metropolis in Metropolis
+1-888-389-4121
203 East Front St., Metropolis, IL 62960 ~26.33 miles east of Cairo
  • Economical Riverfront hotel
  • Comp. Breakfast
  • Bathroom needs cleaning
  • Most guests found the staff to be very friendly
Econo Lodge : 1415 East 5th St.
+1-888-675-2083
1415 East 5th St., Metropolis, IL 62960 ~27.39 miles east of Cairo
  • Low priced property
  • 45 sleeping rooms in hotel
Econo Lodge
+1-800-716-8490
5120 Hinkleville Rd., Paducah, KY 42001 ~27.58 miles east of Cairo
  • Economical Airport hotel
  • Hotel has 2 floors
Courtyard by Marriott Cape Girardeau Downtown : 400 Broadway St.
+1-800-805-5223
400 Broadway St., Cape Girardeau, MO 63701 ~27.66 miles northwest of Cairo
  • Affordable Downtown hotel
  • Check in time: 3:00 pm
Baymont Inn & Suites Paducah - Paducah
+1-888-965-1860
5300 Old Cairo Rd., Paducah, KY 42001 ~27.67 miles east of Cairo
  • Three Star property
  • 3 floors in hotel
Drury Suites Paducah
+1-888-788-5576
2930 James Sanders Blvd., Paducah, KY 42001 ~27.73 miles east of Cairo
  • 3 star Suburban property
  • Check-in: 3:00 PM
  • Affordable food
  • Suite was spacious
From$99
Very Good 4.5 /5Review Score CallBookMore Details
Quality Suites
+1-888-897-9207
2880 James Sanders Blvd., Paducah, KY 42001 ~27.76 miles east of Cairo
  • Low-priced Highway property
  • Hotel has 59 suites
Country Inn & Suites in Paducah
+1-888-311-4278
145 Mcbride Lane, Paducah, KY 42001 ~27.83 miles east of Cairo
  • Affordable Highway hotel
  • 17 suites in property
From$49
Very Good 4.0 /5Reviews CallBookMore Details
Next 25 Cairo Hotels >  [1 - 25 of 50]    
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Graph: Upcoming 20 Days of Cairo Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cairo, IL discounts available. The chart reflects the cheapest Cairo hotel for each day and each star rating category.

FAQs about hotels in Cairo

What are the best rated hotels in Cairo?

Auburn Place Suites, Hampton Inn Cape Girardeau I 55 East and Travel Inn & Suites are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels in Cairo?

Harrah's Metropolis Hotel & Casino, Quality Inn Cairo I-57 and Drury Inn & Suites Sikeston are the top 3 luxury hotels near Cairo city center.

What hotels are closest to the city center of Cairo?

Quality Inn Cairo I-57, Super 8 by Wyndham Charleston MO, and Quality Inn are the properties closest to Cairo city center.

What are the best independent hotels in Cairo?

Auburn Place Suites, Travel Inn & Suites and Drury Suites Paducah are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Cairo?

Fairfield Inn & Suites by Marriott Paducah, Residence Inn and Courtyard by Marriott Cape Girardeau Downtown are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Cairo?

Quality Inn & Suites Metropolis I-24, Comfort Inn Paducah and Quality Inn Cairo I-57 are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Cairo?

Holiday Inn Express Hotel & Suites Paducah West An Ihg Hotel, Holiday Inn Express & Suites Cape Girardeau I 55 and Holiday Inn Express Sikeston are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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