Star Rating
Hotel Name
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Cairo Hotels, Motels & Accommodations

Eagle Inn
+1-888-690-5281
2811 East Marshall St., Charleston, MO 63834 ~9.29 miles southwest of Cairo
  • 2 star hotel
  • Check-in: 3:00PM
Super 8 : 310 South Story
+1-800-230-4134
310 South Story, Charleston, MO 63834 ~10.14 miles southwest of Cairo
  • 2 star Highway hotel
  • Free complimentary breakfast
Quality Inn 102 Drake St., Charleston, MO 63834 ~11.82 miles southwest of Cairo
  • Two-star Highway hotel
  • Fitness / Gym is on-site
Best Western Plus Sikeston in Sikeston 120 South Interstate Dr., Sikeston, MO 63801 ~20.97 miles west of Cairo
  • Economy Highway property
  • Access to gym on-site
From$63
Very Good 4.5 /5Review Score Call
Americas Best Value Inn & Suites : 220 South Interstate Dr. 220 South Interstate Dr., Sikeston, MO 63801 ~21.11 miles west of Cairo
  • 2-star hotel
  • Check in time: 03:00 PM
Comfort Inn & Suites - Sikeston
+1-800-997-5149
109 Matthews Lane, Sikeston, MO 63801 ~21.36 miles west of Cairo
  • Affordable Highway property
  • Hotel has 17 suites
Drury Inn & Suites Sikeston in Sikeston
+1-888-690-5281
2608 East Malone Ave., Sikeston, MO 63801 ~21.42 miles west of Cairo
  • 3-star Highway hotel
  • Check in: 3:00 PM
From$107
Very Good 4.5 /5Hotel Reviews Call
Super 8
+1-800-230-4134
2609 East Malone Ave., Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Inexpensive Convention Center hotel
  • 2 floors in hotel
Pear Tree Inn Sikeston : 2602 East Malone
+1-800-997-5148
2602 East Malone, Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Mid-scale Suburban property
  • Hotel has 2 suites
Residence Inn in Paducah 3900 Coleman Crossing Circle, Paducah, KY 42001 ~25.70 miles east of Cairo
  • Three Star Suburban property
  • Comp. Breakfast
Pear Tree Inn Paducah
+1-888-305-3366
5006 Hinkleville Rd., Paducah, KY 42001 ~25.80 miles east of Cairo
  • Inexpensive Suburban property
  • 2 floors in hotel
Baymont Inn & Suites Metropolis Il 203 East Front St., Metropolis, IL 62960 ~26.33 miles east of Cairo
  • Inexpensive Riverfront hotel
  • Fitness / Gym is on-site
Comfort Suites of Paducah - Paducah
+1-888-690-5281
2880 James Sanders Blvd., Paducah, KY 42001 ~27.72 miles east of Cairo
  • Mid-scale property
  • Gym / Fitness Center Available
From$65
Very Good 4.0 /5Reviews Call
Drury Suites Paducah
+1-800-230-4134
2930 James Sanders Blvd., Paducah, KY 42001 ~27.73 miles east of Cairo
  • Midscale Suburban property
  • Comp. Breakfast
From$109
Very Good 4.5 /5Review Score Call
Country Inn & Suites : 145 Mcbride Lane
+1-800-997-5148
145 Mcbride Lane, Paducah, KY 42001 ~27.83 miles east of Cairo
  • 3 star Highway hotel
  • 60 rooms in hotel
From$65
Very Good 4.0 /5Reviews Call
La Quinta Inn & Suites : 3960 Coleman Crossing Circle 3960 Coleman Crossing Circle, Paducah, KY 42001 ~27.93 miles east of Cairo
  • 3 star Highway property
  • 4 floors in property
From$80
Very Good 4.5 /5Review Score Call
Candlewood Suites 3940 Coleman Crossing Circle, Paducah, KY 42001 ~27.94 miles east of Cairo
  • Low Cost Rural property
  • Access to gym on-site
Comfort Inn Paducah 5135 Old Cairo Rd., Paducah, KY 42001 ~28.01 miles east of Cairo
  • Two-star hotel
  • Hotel has 66 rooms
Econo Lodge Paducah in Paducah
+1-888-690-5281
5106 Old Cairo Rd., Paducah, KY 42001 ~28.01 miles east of Cairo
  • 2 star hotel
From$75
Very Good 4.0 /5Review Score Call
Fairfield Inn & Suites in Paducah 3950 Coleman Crossing Circle, Paducah, KY 42001 ~28.03 miles east of Cairo
  • Affordable Rural hotel
  • 32 suites in property
Hampton Inn & Suites in Paducah
+1-800-997-5148
3901 Coleman Crossing Circle, Paducah, KY 42001 ~28.08 miles east of Cairo
  • 3-star Highway hotel
  • 108 rooms in property
From$109
Very Good 4.5 /5Guest Reviews Call
Super 8 Metropolis
+1-888-690-5247
2055 East 5th St., Metropolis, IL 62960 ~28.13 miles east of Cairo
  • Inexpensive Highway hotel
  • 2 floors in hotel
From$42
Very Good 4.0 /5Review Score Call
Holiday Inn Express
+1-888-305-3366
3994 Hinkleville Rd., Paducah, KY 42001 ~28.13 miles east of Cairo
  • Low Cost Highway property
  • 3 floors in hotel
Courtyard Paducah Kentucky
+1-800-997-5149
3835 Technology Dr., Paducah, KY 42001 ~28.32 miles east of Cairo
  • Midscale Suburban property
  • 100 rooms in hotel
From$79
Very Good 4.0 /5Read Reviews Call
Drury Inn Paducah
+1-888-690-5281
3975 Hinkleville Rd., Paducah, KY 42001 ~28.73 miles east of Cairo
  • Midscale Suburban hotel
  • Hotel has 13 suites
From$79
Very Good 4.5 /5Reviews Call
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