Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.


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Cairo Hotels & Accommodations

Photo of Eagle InnEagle Inn
+1-800-230-4134
$44+

2811 East Marshall St., Charleston, MO 63834~9.29 Miles from Cairo
Exterior of Super 8Super 8
+1-800-997-5148
$45+

310 South Story, Charleston, MO 63834
  • 3.5/5, Average Reviews
  • Economical Highway property
  • Check-in: 3:00pm
~10.14 Miles from Cairo
Image of Quality InnQuality Inn
+1-800-997-5149
$76+

102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Latest Reviews
  • Low Cost Highway property
  • 2 floors in hotel
~11.82 Miles from Cairo
Exterior of Best Western Plus SikestonBest Western Plus Sikeston in Sikeston
+1-800-230-4134
$69+

120 South Interstate Dr., Sikeston, MO 63801
  • Two-star Highway property
  • Hotel has an eco-friendly policy See more
~20.97 Miles from Cairo
Photo of Comfort Inn & SuitesComfort Inn & Suites
+1-800-997-5148
$80+

109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Reviews
  • Midscale Highway hotel
  • Hotel has 17 suites
~21.36 Miles from Cairo
Photo of Drury Inn & Suites SikestonDrury Inn & Suites Sikeston
+1-800-997-5149
$99+

2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Review Score
  • Midscale Highway hotel
  • Hotel has 5 floors
~21.42 Miles from Cairo
Exterior of Super 8Super 8 in Sikeston
+1-800-230-4134
$44+

2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Guest Reviews
  • Economical Convention Center property
  • Hotel has 2 floors
~21.42 Miles from Cairo
Image of Pear Tree Inn SikestonPear Tree Inn Sikeston - Sikeston
+1-800-997-5148
$69+

2602 East Malone, Sikeston, MO 63801
  • Affordable Suburban property
  • Free breakfast available
~21.42 Miles from Cairo
Residence Inn
+1-800-997-5149
$94+

3900 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Hotel Reviews
  • Three Star Suburban property
  • Fitness + Health Center
~25.70 Miles from Cairo
Pear Tree Inn Paducah - Paducah
+1-800-230-4134
$64+

5006 Hinkleville Rd., Paducah, KY 42001
  • 4.0/5, Very Good Review Score
  • Low priced Suburban hotel
  • Hotel has 60 rooms
~25.80 Miles from Cairo
Baymont Inn & Suites Metropolis Il
+1-800-997-5148
$41+

203 East Front St., Metropolis, IL 62960
  • 3.0/5, Average Recent Reviews
  • Cheap Riverfront property
  • 120 rooms in hotel
~26.33 Miles from Cairo
Comfort Suites of Paducah
+1-800-997-5149
$65+

2880 James Sanders Blvd., Paducah, KY 42001
  • 4.0/5, Very Good Reviews
  • 3 star property
  • Hotel has 2 floors
~27.72 Miles from Cairo
Drury Suites Paducah
+1-800-230-4134
$104+

2930 James Sanders Blvd., Paducah, KY 42001
  • 4.5/5, Very Good Guest Reviews
  • Mid-scale Suburban property
  • Gym / Fitness Center Available
~27.73 Miles from Cairo
Country Inn & Suites : 145 Mcbride Lane
+1-800-997-5148
$65+

145 Mcbride Lane, Paducah, KY 42001
  • 4.0/5, Very Good Recent Reviews
  • 3 star Highway property
  • 3 floors in hotel
~27.83 Miles from Cairo
La Quinta Inn & Suites - Paducah
+1-800-997-5149
$83+

3960 Coleman Crossing Circle, Paducah, KY 42001
  • Midscale Highway hotel
  • Hotel has 77 rooms
~27.93 Miles from Cairo
Candlewood Suites
+1-800-230-4134
$65+

3940 Coleman Crossing Circle, Paducah, KY 42001
  • 4.0/5, Very Good Hotel Reviews
  • Two-star Rural hotel
  • Hotel has 4 floors
~27.94 Miles from Cairo
Photo of Comfort Inn PaducahComfort Inn Paducah
+1-800-997-5148
$70+

5135 Old Cairo Rd., Paducah, KY 42001
  • 4.5/5, Very Good Hotel Reviews
  • Inexpensive property
  • Hotel has 3 floors
~28.01 Miles from Cairo
Econo Lodge Paducah
+1-800-997-5149
$75+

5106 Old Cairo Rd., Paducah, KY 42001~28.01 Miles from Cairo
Fairfield Inn & Suites in Paducah
+1-800-230-4134
$77+

3950 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Review Score
  • 3 star Rural hotel
  • Gym is available on property
~28.03 Miles from Cairo
Hampton Inn & Suites : 3901 Coleman Crossing Circle
+1-800-997-5148
$109+

3901 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Hotel Reviews
  • Affordable Highway hotel
  • Check-in time: 3:00 pm
~28.08 Miles from Cairo

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