Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.


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Cairo Hotels/Accommodations

Image of Eagle InnEagle Inn
+1-800-230-4134
$44+

2811 East Marshall St., Charleston, MO 63834~9.29 Miles from Cairo
Image of Super 8Super 8
+1-800-997-5148
$45+

310 South Story, Charleston, MO 63834
  • 3.5/5, Average Review Score
  • 2-star Highway property
  • Hotel has 60 rooms
~10.14 Miles from Cairo
Exterior of Quality InnQuality Inn in Charleston
+1-800-997-5149
$76+

102 Drake St., Charleston, MO 63834
  • 3.0/5, Average Read Reviews
  • Two-star Highway property
  • 2 floors in property
~11.82 Miles from Cairo
Photo of Best Western Plus SikestonBest Western Plus Sikeston - Sikeston
+1-800-230-4134
$69+

120 South Interstate Dr., Sikeston, MO 63801
  • Economy Highway hotel
  • Free breakfast available
~20.97 Miles from Cairo
Image of Comfort Inn & SuitesComfort Inn & Suites
+1-800-997-5148
$80+

109 Matthews Lane, Sikeston, MO 63801
  • 3.5/5, Average Read Reviews
  • 3-star Highway property
  • Hotel has 17 suites
~21.36 Miles from Cairo
Exterior of Super 8Super 8 : 2609 East Malone Ave.
+1-800-997-5149
$44+

2609 East Malone Ave., Sikeston, MO 63801
  • 3.0/5, Average Reviews
  • Economical Convention Center hotel
  • Hotel has 62 rooms
~21.42 Miles from Cairo
Exterior of Drury Inn & Suites SikestonDrury Inn & Suites Sikeston in Sikeston
+1-800-230-4134
$99+

2608 East Malone Ave., Sikeston, MO 63801
  • 4.5/5, Very Good Reviews
  • 3-star Highway property
  • 4 meeting rooms in property
~21.42 Miles from Cairo
Exterior of Pear Tree Inn SikestonPear Tree Inn Sikeston
+1-800-997-5148
$69+

2602 East Malone, Sikeston, MO 63801
  • 3 star Suburban property
  • 2 suites in property
~21.42 Miles from Cairo
Residence Inn - Paducah
+1-800-997-5149
$94+

3900 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Hotel Reviews
  • Affordable Suburban hotel
  • Access to gym on-site
~25.70 Miles from Cairo
Pear Tree Inn Paducah in Paducah
+1-800-230-4134
$64+

5006 Hinkleville Rd., Paducah, KY 42001
  • 4.0/5, Very Good Guest Reviews
  • Low Cost Suburban hotel
  • 2 floors in hotel
~25.80 Miles from Cairo
Baymont Inn & Suites Metropolis Il - Metropolis
+1-800-997-5148
$41+

203 East Front St., Metropolis, IL 62960
  • 3.0/5, Average Reviews
  • Two star Riverfront hotel
  • Hotel has 2 meeting rooms
~26.33 Miles from Cairo
Comfort Suites of Paducah - Paducah
+1-800-997-5149
$65+

2880 James Sanders Blvd., Paducah, KY 42001
  • 4.0/5, Very Good Guest Reviews
  • Three Star hotel
  • Check in time: 3:00 pm
~27.72 Miles from Cairo
Drury Suites Paducah - Paducah
+1-800-230-4134
$104+

2930 James Sanders Blvd., Paducah, KY 42001
  • 4.5/5, Very Good Latest Reviews
  • Mid-scale Suburban hotel
  • 2 meeting rooms in hotel
~27.73 Miles from Cairo
Country Inn & Suites : 145 Mcbride Lane
+1-800-997-5148
$65+

145 Mcbride Lane, Paducah, KY 42001
  • 4.0/5, Very Good Hotel Reviews
  • 3-star Highway property
  • 60 rooms in property
~27.83 Miles from Cairo
La Quinta Inn & Suites : 3960 Coleman Crossing Circle
+1-800-997-5149
$83+

3960 Coleman Crossing Circle, Paducah, KY 42001
  • 3 star Highway hotel
  • 77 rooms in hotel
~27.93 Miles from Cairo
Candlewood Suites : 3940 Coleman Crossing Circle
+1-800-230-4134
$65+

3940 Coleman Crossing Circle, Paducah, KY 42001
  • 4.0/5, Very Good Read Reviews
  • Two star Rural hotel
  • Check-in: 3:00pm
~27.94 Miles from Cairo
Exterior of Comfort Inn PaducahComfort Inn Paducah : 5135 Old Cairo Rd.
+1-800-997-5148
$70+

5135 Old Cairo Rd., Paducah, KY 42001
  • 4.5/5, Very Good Guest Reviews
  • 2 star property
  • Complimentary breakfast is offered
~28.01 Miles from Cairo
Econo Lodge Paducah : 5106 Old Cairo Rd.
+1-800-997-5149
$75+

5106 Old Cairo Rd., Paducah, KY 42001~28.01 Miles from Cairo
Fairfield Inn & Suites
+1-800-230-4134
$77+

3950 Coleman Crossing Circle, Paducah, KY 42001~28.03 Miles from Cairo
Hampton Inn & Suites
+1-800-997-5148
$109+

3901 Coleman Crossing Circle, Paducah, KY 42001
  • 4.5/5, Very Good Latest Reviews
  • 3-star Highway property
  • Fitness + Health Center
~28.08 Miles from Cairo

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