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Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.

Cairo Hotels/Accommodations

Quality Inn
+1-888-389-4121
13201 Kessler Rd., Cairo, IL 62914
  • Three Star Highway hotel
  • Hotel has 2 floors
  • Friendly service
  • Staff nice
Super 8 in Charleston
+1-888-675-2083
310 South Story, Charleston, MO 63834 ~10.14 miles southwest of Cairo
  • Economy Highway hotel
  • Complimentary breakfast is offered
Quality Inn
+1-800-716-8490
102 Drake St., Charleston, MO 63834 ~11.90 miles southwest of Cairo
  • Two star Highway property
  • Hotel has 9 suites
Americas Best Value Inn in Ullin
+1-800-805-5223
128 Cheekwood Lane, Ullin, IL 62992 ~17.90 miles north of Cairo
  • Two star hotel
  • 2 floors in hotel
Motel 6 Sikeston Mo #4328
+1-888-965-1860
110 South Interstate Dr., SIKESTON, MISSOURI 63801 ~21.01 miles west of Cairo
  • Inexpensive hotel
Best Western Plus Sikeston
+1-888-788-5576
120 South Interstate Dr., Sikeston, MO 63801 ~21.04 miles west of Cairo
  • Cheap Highway property
  • Free breakfast
Days Inn & Suites by Wyndham Sikeston : 220 South Interstate Dr.
+1-888-897-9207
220 South Interstate Dr., Sikeston, MO 63801 ~21.11 miles west of Cairo
  • Cheap property
  • Check-in: 03:00 PM
Country Hearth Inn & Suites Sikeston in Sikeston
+1-888-311-4278
100 Matthews Lane, Sikeston, MO 63801 ~21.35 miles west of Cairo
  • Affordable Highway property
  • Hotel has 2 floors
  • Horrible vibe
  • Average hotel building
From$80
Very Good 4.5 /5Read Reviews CallBookMore Details
Super 8 by Wyndham Sikeston / Miner Area
+1-888-469-4795
2609 East Malone, Sikeston, MO 63801 ~21.37 miles west of Cairo
  • Low Cost Convention Center hotel
  • Complimentary breakfast is offered
Comfort Inn : 109 Matthews Lane
+1-888-734-9421
109 Matthews Lane, Sikeston, MO 63801 ~21.39 miles west of Cairo
  • Mid-scale Highway property
  • Access to gym on-site
Drury Inn & Suites Sikeston in Sikeston
+1-888-841-5292
2608 East Malone Ave., Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Three Star Highway hotel
  • Check in: 3:00 PM
  • Generally very clean
  • Internet is average
From$104
Very Good 4.5 /5Read Reviews CallBookMore Details
Pear Tree Inn Sikeston - Sikeston
+1-888-455-5160
2602 East Malone, Sikeston, MO 63801 ~21.42 miles west of Cairo
  • 3-star Suburban hotel
  • Check-in: 3:00 PM
  • Beautiful lobby
  • Clean rooms
Holiday Inn Express Sikeston
+1-888-965-8297
115 Hospitality Dr., Sikeston, MO 63801 ~24.55 miles west of Cairo
  • Mid-scale hotel
  • 73 sleeping rooms in hotel
Hampton Inn Sikeston Mo : 1240 Commerce Dr.
+1-888-906-6358
1240 Commerce Dr., Sikeston, MO 63801 ~24.92 miles west of Cairo
  • Affordable hotel
  • Hotel has 4 floors
From$90
Very Good 4.5 /5Review Score CallBookMore Details
Residence Inn : 3900 Coleman Crossing Circle
+1-888-749-6785
3900 Coleman Crossing Circle, Paducah, KY 42001 ~25.70 miles east of Cairo
  • Mid-scale Suburban property
  • 3 floors in property
  • Clean rooms
  • Clean Rooms
Pear Tree Inn Paducah in Paducah
+1-888-878-9982
5006 Hinkleville Rd., Paducah, KY 42001 ~25.80 miles east of Cairo
  • 2-star Suburban hotel
  • Free comp. breakfast
  • Clean ,and very pleasant overall
  • Old style TVs
From$55
Very Good 4.0 /5Review Score CallBookMore Details
Harrah's Metropolis Hotel & Casino in Metropolis
+1-888-389-4485
100 East Front St., Metropolis, IL 62960 ~26.30 miles east of Cairo
  • Expensive property
  • Hotel has 252 rooms
From$160
Very Good 4.0 /5Guest Reviews CallBookMore Details
Baymont Inn & Suites Metropolis Il
+1-888-389-4121
203 East Front St., Metropolis, IL 62960 ~26.33 miles east of Cairo
  • Two-star Riverfront property
  • Access to gym on-site
  • Food is delicious
  • Bathroom needs cleaning
Econo Lodge
+1-888-675-2083
1415 East 5th St., Metropolis, IL 62960 ~27.39 miles east of Cairo
  • 2 star hotel
  • Check-in time: 11:00
Econo Lodge - Paducah
+1-800-716-8490
5120 Hinkleville Rd., Paducah, KY 42001 ~27.58 miles east of Cairo
  • Economy Airport hotel
  • 75 rooms in property
Courtyard Cape Girardeau Downtown in Cape Girardeau
+1-800-805-5223
400 Broadway St., Cape Girardeau, MO 63701 ~27.66 miles northwest of Cairo
  • Midscale Downtown hotel
  • 78 rooms in hotel
From$80
Very Good 4.5 /5Review Score CallBookMore Details
Baymont Inn & Suites Paducah
+1-888-965-1860
5300 Old Cairo Rd., Paducah, KY 42001 ~27.67 miles east of Cairo
  • 3 star hotel
  • Hotel has 3 floors
Drury Suites Paducah - Paducah
+1-888-788-5576
2930 James Sanders Blvd., Paducah, KY 42001 ~27.73 miles east of Cairo
  • 3 star Suburban property
  • Hotel has a green policy See policy
  • Spacious rooms
  • Tasty breakfast
From$99
Very Good 4.5 /5Reviews CallBookMore Details
Quality Suites - Paducah
+1-888-897-9207
2880 James Sanders Blvd., Paducah, KY 42001 ~27.76 miles east of Cairo
  • Inexpensive Highway hotel
  • Free complimentary breakfast
Country Inn & Suites
+1-888-311-4278
145 Mcbride Lane, Paducah, KY 42001 ~27.83 miles east of Cairo
  • Midscale Highway property
  • Check in time: 4pm
Next 25 Cairo Hotels >  [1 - 25 of 50]    
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Graph: Upcoming 20 Days of Cairo Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cairo, IL discounts available. The chart reflects the cheapest Cairo hotel for each day and each star rating category.

FAQs about hotels in Cairo

What are the most favored hotels in Cairo?

Homewood Suites by Hilton Paducah, Auburn Place Suites and Hampton Inn Cape Girardeau I 55 East are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels in Cairo?

Harrah's Metropolis Hotel & Casino, Quality Inn and Country Hearth Inn & Suites Sikeston are the top 3 luxury hotels near Cairo city center.

What hotels are closest to the city center of Cairo?

Quality Inn, Super 8, and Quality Inn are the properties closest to Cairo city center.

What are the best independent hotels in Cairo?

Auburn Place Suites, Drury Suites Paducah and Auburn Place Hotel & Suites are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Cairo?

Residence Inn, Courtyard Cape Girardeau Downtown and Fairfield Inn & Suites Paducah are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Cairo?

Quality Inn, Quality Suites and Comfort Inn Paducah are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Cairo?

Holiday Inn Express & Suites Paducah West, Holiday Inn Express & Suites Cape Girardeau I 55 and Holiday Inn Express Sikeston are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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