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Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.

Cairo Hotels, Motels & Accommodations

Eagle Inn : 2811 East Marshall St.
+1-888-690-5281
2811 East Marshall St., Charleston, MO 63834 ~9.29 miles southwest of Cairo
  • 2-star hotel
  • Check-in: 3:00PM
From$44
Average 3.5 /5Reviews Call
Super 8 310 South Story, Charleston, MO 63834 ~10.14 miles southwest of Cairo
  • Low-priced Highway property
  • Free breakfast
Quality Inn : 102 Drake St. 102 Drake St., Charleston, MO 63834 ~11.82 miles southwest of Cairo
  • Economy Highway property
  • 9 suites in hotel
Best Western Plus Sikeston 120 South Interstate Dr., Sikeston, MO 63801 ~20.97 miles west of Cairo
  • Two-star Highway hotel
  • Hotel has a green policy Learn more
From$89
Very Good 4.5 /5Read Reviews Call
Americas Best Value Inn & Suites in Sikeston 220 South Interstate Dr., Sikeston, MO 63801 ~21.11 miles west of Cairo
  • 2 star hotel
  • Hotel has 60 suites
From$64
Average 3.5 /5Reviews Call
Country Hearth Inn & Suites Sikeston in Sikeston 100 Matthews Lane, Sikeston, MO 63801 ~21.35 miles west of Cairo
  • 2-star Highway property
  • Free complimentary breakfast
Comfort Inn & Suites
+1-800-997-5149
109 Matthews Lane, Sikeston, MO 63801 ~21.36 miles west of Cairo
  • Mid-scale Highway property
  • Free complimentary breakfast
Drury Inn & Suites Sikeston 2608 East Malone Ave., Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Mid-scale Highway hotel
  • Hotel has 5 floors
From$109
Very Good 4.5 /5Review Score Call
Super 8 in Sikeston
+1-800-230-4134
2609 East Malone Ave., Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Two star Convention Center property
  • 62 sleeping rooms in hotel
Pear Tree Inn Sikeston 2602 East Malone, Sikeston, MO 63801 ~21.42 miles west of Cairo
  • 3 star Suburban property
  • 2 suites in hotel
Residence Inn in Paducah 3900 Coleman Crossing Circle, Paducah, KY 42001 ~25.70 miles east of Cairo
  • 3 star Suburban hotel
  • Check-in time: 3:00PM
Pear Tree Inn Paducah : 5006 Hinkleville Rd. 5006 Hinkleville Rd., Paducah, KY 42001 ~25.80 miles east of Cairo
  • Economical Suburban property
  • Hotel has 2 floors
From$62
Very Good 4.0 /5Reviews Call
Baymont Inn & Suites Metropolis Il 203 East Front St., Metropolis, IL 62960 ~26.33 miles east of Cairo
  • Cheap Riverfront property
  • Gym / Fitness Center Available
Drury Suites Paducah in Paducah 2930 James Sanders Blvd., Paducah, KY 42001 ~27.73 miles east of Cairo
  • 3 star Suburban hotel
  • Free complimentary breakfast
From$114
Very Good 4.5 /5Latest Reviews Call
Quality Suites 2880 James Sanders Blvd., Paducah, KY 42001 ~27.76 miles east of Cairo
  • 3 star Highway property
  • Hotel has 59 suites
From$60
Very Good 4.0 /5Read Reviews Call
Country Inn & Suites
+1-800-230-4134
145 Mcbride Lane, Paducah, KY 42001 ~27.83 miles east of Cairo
  • Midscale Highway property
  • Check in: 4pm
Thrifty Inn in Paducah 5004 Hinkleville Rd., Paducah, KY 42001 ~27.85 miles east of Cairo
  • 2-star property
  • 4 floors in hotel
La Quinta Inn & Suites 3960 Coleman Crossing Circle, Paducah, KY 42001 ~27.93 miles east of Cairo
  • Affordable Highway hotel
  • 77 rooms in property
From$85
Excellent 5.0 /5Review Score Call
Candlewood Suites in Paducah 3940 Coleman Crossing Circle, Paducah, KY 42001 ~27.94 miles east of Cairo
  • Two star Rural property
  • Check in time: 3:00pm
From$55
Very Good 4.0 /5Reviews Call
Comfort Inn Paducah 5135 Old Cairo Rd., Paducah, KY 42001 ~28.01 miles east of Cairo
  • Low priced hotel
  • 3 floors in property
From$70
Very Good 4.5 /5Review Score Call
Econo Lodge Paducah in Paducah
+1-800-997-5149
5106 Old Cairo Rd., Paducah, KY 42001 ~28.01 miles east of Cairo
  • 2 star hotel
Fairfield Inn & Suites - Paducah 3950 Coleman Crossing Circle, Paducah, KY 42001 ~28.03 miles east of Cairo
  • 3 star Rural hotel
  • Access to gym on-site
Hampton Inn & Suites - Paducah
+1-800-230-4134
3901 Coleman Crossing Circle, Paducah, KY 42001 ~28.08 miles east of Cairo
  • 3 star Highway property
  • 32 suites in property
From$109
Very Good 4.5 /5Recent Reviews Call
Super 8 Metropolis : 2055 East 5th St.
+1-800-997-5148
2055 East 5th St., Metropolis, IL 62960 ~28.13 miles east of Cairo
  • Low priced Highway hotel
  • 2 floors in hotel
Holiday Inn Express - Paducah 3994 Hinkleville Rd., Paducah, KY 42001 ~28.13 miles east of Cairo
  • 2 star Highway property
  • Check-in: 3:00 PM
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