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Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.

Cairo Hotels & Accommodations

Quality Inn
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-618-734-0215
13201 Kessler Rd., Cairo, IL 62914
  • Affordable hotel
  • Free breakfast available
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From$80
Average 3.5 /5Reviews CallBookMore Details
Super 8 - Charleston
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 1-573-683-2125
310 South Story, Charleston, MO 63834 ~10.14 miles southwest of Cairo
  • Cheap Highway hotel
  • Hotel has 7 suites
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From$45
Average 3.5 /5Recent Reviews CallBookMore Details
Quality Inn - Charleston
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 1-573-683-4200
102 Drake St., Charleston, MO 63834 ~11.90 miles southwest of Cairo
  • Two-star Highway hotel
  • 9 suites in hotel
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From$64
Average 3.5 /5Review Score CallBookMore Details
Americas Best Value Inn
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 1-618-845-3700
128 Cheekwood Lane, Ullin, IL 62992 ~17.90 miles north of Cairo
  • Two star hotel
  • 2 floors in property
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From$60
Very Good 4.0 /5Latest Reviews CallBookMore Details
Best Western Plus Sikeston : 120 South Interstate Dr.
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863 Front Desk: 1-573-481-9500
120 South Interstate Dr., Sikeston, MO 63801 ~21.04 miles west of Cairo
  • Economy Highway hotel
  • Fitness / Gym is on-site
More Photos Photo of Best Western Plus Sikeston
From$74
Very Good 4.5 /5Read Reviews CallBookMore Details
Motel 6 Sikeston Mo : 110 South Interstate Dr.
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863 Front Desk: 1-573-471-7400
110 South Interstate Dr., Sikeston, MO 63801 ~21.05 miles west of Cairo
  • Inexpensive hotel
  • 46 rooms in property
More Photos Image of Motel 6 Sikeston Mo
From$60
Average 3.0 /5Guest Reviews CallBookMore Details
Americas Best Value Inn & Suites : 220 South Interstate Dr.
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 1-573-471-9700
220 South Interstate Dr., Sikeston, MO 63801 ~21.11 miles west of Cairo
  • Cheap hotel
  • 60 rooms in property
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From$55
Average 3.5 /5Recent Reviews CallBookMore Details
Country Hearth Inn & Suites Sikeston in Sikeston
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-573-472-4400
100 Matthews Lane, Sikeston, MO 63801 ~21.35 miles west of Cairo
  • Cheap Highway property
  • 2 floors in property
  • The majority of guests said rooms were dirty
  • Lobby was hot
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From$60
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Comfort Inn & Suites
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863
109 Matthews Lane, Sikeston, MO 63801 ~21.36 miles west of Cairo
  • Three Star Highway hotel
  • 3 floors in hotel
  • Location is ok
  • Clean
More Photos Exterior of Comfort Inn & Suites
From$80
Average 3.5 /5Hotel Reviews CallBookMore Details
Super 8 in Sikeston
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863
2609 East Malone Ave., Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Cheap Convention Center property
  • Free breakfast
More Photos Photo of Super 8
From$44
Average 3.0 /5Recent Reviews CallBookMore Details
Drury Inn & Suites Sikeston - Sikeston
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 1-800-436-1126
2608 East Malone Ave., Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Midscale Highway hotel
  • 154 sleeping rooms in hotel
  • Most guests were happy with the price
  • Clean rooms
More Photos Exterior of Drury Inn & Suites Sikeston
From$85
Very Good 4.5 /5Guest Reviews CallBookMore Details
Pear Tree Inn Sikeston - Sikeston
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863 Front Desk: 1-800-325-0720
2602 East Malone, Sikeston, MO 63801 ~21.42 miles west of Cairo
  • 3-star Suburban property
  • Access to gym on-site
  • Most guests thought it was clean
  • Bar is awesome
More Photos Exterior of Pear Tree Inn Sikeston
From$75
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Holiday Inn Express & Suites Sikeston
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863 Front Desk: 1-573-475-9522
115 Hospitality Dr., Sikeston, MO 63801 ~24.54 miles west of Cairo
  • Low priced hotel
  • Gym is available on property
More Photos Image of Holiday Inn Express & Suites Sikeston
From$60
Very Good 4.5 /5Review Score CallBookMore Details
Days Inn Sikeston
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 1-573-471-3930
1330 South Main St., Sikeston, MO 63801 ~24.66 miles west of Cairo
  • Two star property
  • Check in time: 11:00 AM
More Photos Photo of Days Inn Sikeston
From$60
Poor 2.0 /5Latest Reviews CallBookMore Details
Residence Inn
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-270-444-3966
3900 Coleman Crossing Circle, Paducah, KY 42001 ~25.70 miles east of Cairo
  • Mid-scale Suburban hotel
  • Free breakfast available
  • Popular among families
  • Clean room
More Photos Photo of Residence Inn
From$84
Very Good 4.5 /5Reviews CallBookMore Details
Pear Tree Inn Paducah
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 1-800-436-1126
5006 Hinkleville Rd., Paducah, KY 42001 ~25.80 miles east of Cairo
  • Economical Suburban hotel
  • Hotel has 2 floors
  • World class service
  • Everything was very enjoyable
More Photos Exterior of Pear Tree Inn Paducah
From$62
Very Good 4.0 /5Guest Reviews CallBookMore Details
Baymont Inn & Suites Metropolis Il
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 1-618-524-5678
203 East Front St., Metropolis, IL 62960 ~26.33 miles east of Cairo
  • Low Cost Riverfront property
  • 8 suites in hotel
  • Fab pool and cheerful service
  • Dressing getting ready
More Photos Photo of Baymont Inn & Suites Metropolis Il
From$45
Average 3.5 /5Guest Reviews CallBookMore Details
Baymont Inn & Suites Paducah - Paducah
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 1-270-443-4343
5300 Old Cairo Rd., Paducah, KY 42001 ~27.67 miles east of Cairo
  • 3-star property
  • 4 suites in hotel
More Photos Image of Baymont Inn & Suites Paducah
From$39
Average 3.5 /5Review Score CallBookMore Details
Drury Suites Paducah
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863 Front Desk: 1-800-436-1126
2930 James Sanders Blvd., Paducah, KY 42001 ~27.73 miles east of Cairo
  • Mid-scale Suburban property
  • 6 floors in property
  • Comfortable beds
  • Free hot breakfast complete with waffle maker
More Photos Photo of Drury Suites Paducah
From$99
Very Good 4.5 /5Latest Reviews CallBookMore Details
Quality Suites in Paducah
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863 Front Desk: 1-270-442-2080
2880 James Sanders Blvd., Paducah, KY 42001 ~27.76 miles east of Cairo
  • 3 star Highway hotel
  • Hotel has 59 suites
More Photos Image of Quality Suites
From$65
Very Good 4.0 /5Guest Reviews CallBookMore Details
Country Inn & Suites - Paducah
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 1-270-442-2201
145 Mcbride Lane, Paducah, KY 42001 ~27.83 miles east of Cairo
  • Affordable Highway property
  • 3 floors in property
More Photos Photo of Country Inn & Suites
From$65
Very Good 4.0 /5Recent Reviews CallBookMore Details
Country Inn & Suites Lithia Springs
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-270-442-2201
960 West Pointe Court, Lithia Springs, GA 30122 ~27.83 miles east of Cairo
  • 3-star Rural hotel
  • 55 suites in property
More Photos Image of Country Inn & Suites Lithia Springs
From$70
Poor 2.5 /5Review Score CallBookMore Details
Super 8 Paducah Ky
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 1-270-442-3334
5001 Hinkleville Rd., Paducah, KY 42001 ~27.85 miles east of Cairo
  • Two star property
  • Check-in time: 11:00 AM
More Photos Photo of Super 8 Paducah Ky
From$60
Average 3.5 /5Recent Reviews CallBookMore Details
Thrifty Inn
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 1-800-445-9410
5004 Hinkleville Rd., Paducah, KY 42001 ~27.85 miles east of Cairo
  • Cheap hotel
  • Hotel has 4 floors
  • Great parking, according to 100%
  • Wifi works great
More Photos Image of Thrifty Inn
From$60
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Thrifty Inn Paducah : 5002 Hinkleville Rd.
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 1-270-444-0157
5002 Hinkleville Rd., Paducah, KY 42001 ~27.87 miles east of Cairo
  • Mid-scale property
  • Check in: 15:00
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From$90
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