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Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.

Cairo Hotels & Accommodations

Quality Inn
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-618-734-0215
13201 Kessler Rd., Cairo, IL 62914
  • Affordable hotel
  • 38 rooms in hotel
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From$80
Very Good 4.0 /5Guest Reviews CallBookMore Details
Super 8
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 1-573-683-2125
310 South Story, Charleston, MO 63834 ~10.14 miles southwest of Cairo
  • Two-star Highway hotel
  • Complimentary breakfast is offered
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From$49
Average 3.5 /5Guest Reviews CallBookMore Details
Quality Inn in Charleston
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 1-573-683-4200
102 Drake St., Charleston, MO 63834 ~11.90 miles southwest of Cairo
  • 2 star Highway property
  • 40 rooms in hotel
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From$67
Average 3.5 /5Latest Reviews CallBookMore Details
Americas Best Value Inn : 128 Cheekwood Lane
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 1-618-845-3700
128 Cheekwood Lane, Ullin, IL 62992 ~17.90 miles north of Cairo
  • Cheap property
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From$60
Very Good 4.0 /5Hotel Reviews CallBookMore Details
Best Western Plus Sikeston : 120 South Interstate Dr.
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863 Front Desk: 1-573-481-9500
120 South Interstate Dr., Sikeston, MO 63801 ~21.04 miles west of Cairo
  • Low-priced Highway property
  • Hotel has a green policy See more
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From$76
Very Good 4.5 /5Reviews CallBookMore Details
Americas Best Value Inn & Suites - Sikeston
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863 Front Desk: 1-573-471-9700
220 South Interstate Dr., Sikeston, MO 63801 ~21.11 miles west of Cairo
  • Low priced hotel
  • Hotel has 60 suites
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From$53
Very Good 4.0 /5Reviews CallBookMore Details
Country Hearth Inn & Suites Sikeston : 100 Matthews Lane
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 1-573-472-4400
100 Matthews Lane, Sikeston, MO 63801 ~21.35 miles west of Cairo
  • 2 star Highway property
  • 40 sleeping rooms in hotel
  • Good parking spaces
  • Breakfast can be improved
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From$60
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Comfort Inn & Suites - Sikeston
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863
109 Matthews Lane, Sikeston, MO 63801 ~21.36 miles west of Cairo
  • Affordable Highway hotel
  • 17 suites in property
  • Location is ok
  • Outlet mall next door
More Photos Image of Comfort Inn & Suites
From$80
Average 3.5 /5Review Score CallBookMore Details
Super 8
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863
2609 East Malone Ave., Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Economy Convention Center property
  • 62 rooms in hotel
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From$44
Average 3.0 /5Recent Reviews CallBookMore Details
Drury Inn & Suites Sikeston in Sikeston
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 1-800-436-1126
2608 East Malone Ave., Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Three Star Highway hotel
  • Hotel has an eco-friendly policy Read more
  • Generally very clean
  • Easy access from highway
More Photos Image of Drury Inn & Suites Sikeston
From$85
Very Good 4.5 /5Latest Reviews CallBookMore Details
Pear Tree Inn Sikeston : 2602 East Malone
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 1-800-325-0720
2602 East Malone, Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Three Star Suburban hotel
  • Gym / Fitness Center Available
  • New rooms
  • Best hotel breakfast
More Photos Image of Pear Tree Inn Sikeston
From$75
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Holiday Inn Express & Suites Sikeston - Sikeston
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863 Front Desk: 1-573-475-9522
115 Hospitality Dr., Sikeston, MO 63801 ~24.54 miles west of Cairo
  • Economy property
  • 73 sleeping rooms in hotel
More Photos Photo of Holiday Inn Express & Suites Sikeston
From$60
Very Good 4.5 /5Review Score CallBookMore Details
Days Inn Sikeston
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863
1330 South Main St., Sikeston, MO 63801 ~24.66 miles west of Cairo
  • Low Cost hotel
  • Check-in: 11:00 AM
More Photos hotel room
From$60
Poor 2.0 /5Guest Reviews CallBookMore Details
Residence Inn in Paducah
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 1-270-444-3966
3900 Coleman Crossing Circle, Paducah, KY 42001 ~25.70 miles east of Cairo
  • 3-star Suburban hotel
  • Check-in: 3:00PM
  • Every guests reviewed said rooms were clean
  • World class service
More Photos Exterior of Residence Inn
From$89
Very Good 4.5 /5Reviews CallBookMore Details
Pear Tree Inn Paducah in Paducah
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-800-436-1126
5006 Hinkleville Rd., Paducah, KY 42001 ~25.80 miles east of Cairo
  • Low-priced Suburban hotel
  • 2 floors in hotel
  • Everything was very enjoyable
  • Best value for money
More Photos Image of Pear Tree Inn Paducah
From$62
Very Good 4.0 /5Recent Reviews CallBookMore Details
Baymont Inn & Suites Metropolis Il : 203 East Front St.
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 1-618-524-5678
203 East Front St., Metropolis, IL 62960 ~26.33 miles east of Cairo
  • Two-star Riverfront hotel
  • Hotel has 120 rooms
  • Dirty coffee cup
  • Bathroom needs cleaning
More Photos Photo of Baymont Inn & Suites Metropolis Il
From$35
Average 3.5 /5Review Score CallBookMore Details
Baymont Inn & Suites Paducah in Paducah
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 1-270-443-4343
5300 Old Cairo Rd., Paducah, KY 42001 ~27.67 miles east of Cairo
  • Affordable hotel
  • 74 rooms in hotel
More Photos Exterior of Baymont Inn & Suites Paducah
From$40
Average 3.5 /5Recent Reviews CallBookMore Details
Drury Suites Paducah : 2930 James Sanders Blvd.
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 1-800-436-1126
2930 James Sanders Blvd., Paducah, KY 42001 ~27.73 miles east of Cairo
  • Midscale Suburban hotel
  • Check in: 3:00 PM
  • Bathroom could be optimized
  • Bar available
More Photos Photo of Drury Suites Paducah
From$90
Very Good 4.5 /5Latest Reviews CallBookMore Details
Quality Suites in Paducah
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863 Front Desk: 1-270-442-2080
2880 James Sanders Blvd., Paducah, KY 42001 ~27.76 miles east of Cairo
  • 3-star Highway property
  • 2 floors in property
More Photos Photo of Quality Suites
From$79
Very Good 4.0 /5Review Score CallBookMore Details
Country Inn & Suites Lithia Springs - Lithia Springs
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863 Front Desk: 1-270-442-2201
960 West Pointe Court, Lithia Springs, GA 30122 ~27.83 miles east of Cairo
  • Affordable Rural hotel
  • Complimentary breakfast is offered
More Photos Photo of Country Inn & Suites Lithia Springs
From$79
Poor 2.5 /5Review Score CallBookMore Details
Country Inn & Suites
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 1-270-442-2201
145 Mcbride Lane, Paducah, KY 42001 ~27.83 miles east of Cairo
  • Mid-scale Highway hotel
  • Comp. Breakfast
More Photos Exterior of Country Inn & Suites
From$65
Very Good 4.0 /5Guest Reviews CallBookMore Details
Super 8 Paducah Ky
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 1-270-442-3334
5001 Hinkleville Rd., Paducah, KY 42001 ~27.85 miles east of Cairo
  • Two-star hotel
  • Check in time: 11:00 AM
More Photos Exterior of Super 8 Paducah Ky
From$60
Average 3.5 /5Review Score CallBookMore Details
Thrifty Inn : 5004 Hinkleville Rd.
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 1-800-445-9410
5004 Hinkleville Rd., Paducah, KY 42001 ~27.85 miles east of Cairo
  • Low Cost property
  • 4 floors in property
  • Bathroom could be optimized
  • Great pool
More Photos Photo of Thrifty Inn
From$60
CallBookMore Details
La Quinta Inn & Suites in Paducah
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 1-270-443-4800
3960 Coleman Crossing Circle, Paducah, KY 42001 ~27.93 miles east of Cairo
  • 3-star Highway property
  • Free complimentary breakfast
More Photos Photo of La Quinta Inn & Suites
From$89
Very Good 4.5 /5Guest Reviews CallBookMore Details
Candlewood Suites - Paducah
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 1-270-442-3969
3940 Coleman Crossing Circle, Paducah, KY 42001 ~27.94 miles east of Cairo
  • Cheap Rural hotel
  • Fitness / Gym is on-site
More Photos Photo of Candlewood Suites
From$60
Very Good 4.0 /5Read Reviews CallBookMore Details
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