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Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.

Cairo Hotels, Motels & Accommodations

Quality Inn - Cairo
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 6187340215
13201 Kessler Rd., Cairo, IL 62914
  • Midscale property
  • Check in: 11:00
More PhotosExterior of Quality Inn
From$80
Very Good 4.0 /5Latest Reviews CallBookMore Details
Super 8 in Charleston
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 15736832125
310 South Story, Charleston, MO 63834 ~10.14 miles southwest of Cairo
  • Two-star Highway property
  • Comp. Breakfast
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From$49
Average 3.5 /5Guest Reviews CallBookMore Details
Quality Inn
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 15736834200
102 Drake St., Charleston, MO 63834 ~11.90 miles southwest of Cairo
  • Cheap Highway property
  • Fitness center on property
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From$67
Average 3.5 /5Hotel Reviews CallBookMore Details
Americas Best Value Inn - Ullin
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 16188453700
128 Cheekwood Lane, Ullin, IL 62992 ~17.90 miles north of Cairo
  • Two star hotel
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From$60
Very Good 4.0 /5Guest Reviews CallBookMore Details
Best Western Plus Sikeston
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863 Front Desk: 15734819500
120 South Interstate Dr., Sikeston, MO 63801 ~21.04 miles west of Cairo
  • Low Cost Highway hotel
  • Hotel has 2 floors
More Photos Exterior of Best Western Plus Sikeston
From$69
Very Good 4.5 /5Read Reviews CallBookMore Details
Americas Best Value Inn & Suites
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863 Front Desk: 15734719700
220 South Interstate Dr., Sikeston, MO 63801 ~21.11 miles west of Cairo
  • Low Cost hotel
  • 60 suites in property
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From$53
Very Good 4.0 /5Recent Reviews CallBookMore Details
Country Hearth Inn & Suites Sikeston
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 15734724400
100 Matthews Lane, Sikeston, MO 63801 ~21.35 miles west of Cairo
  • Two-star Highway hotel
  • 2 floors in property
  • Average amenities
  • The majority of guests said rooms were dirty
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From$60
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Comfort Inn & Suites in Sikeston
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863
109 Matthews Lane, Sikeston, MO 63801 ~21.36 miles west of Cairo
  • Midscale Highway property
  • 17 suites in property
  • Friendly service
  • Clean
More Photos Image of Comfort Inn & Suites
From$80
Average 3.5 /5Latest Reviews CallBookMore Details
Super 8
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863
2609 East Malone Ave., Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Economical Convention Center property
  • Check-in time: 01:00
More Photos Exterior of Super 8
From$44
Average 3.0 /5Guest Reviews CallBookMore Details
Drury Inn & Suites Sikeston
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 18004361126
2608 East Malone Ave., Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Midscale Highway property
  • Hotel has 154 rooms
  • About half of guests complained about the bathroom
  • Most guests thought it was clean
More Photos Photo of Drury Inn & Suites Sikeston
From$85
Very Good 4.5 /5Read Reviews CallBookMore Details
Pear Tree Inn Sikeston in Sikeston
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 18003250720
2602 East Malone, Sikeston, MO 63801 ~21.42 miles west of Cairo
  • Three Star Suburban property
  • Free complimentary breakfast
  • Complimentary beer
  • Comfy beds
More Photos Photo of Pear Tree Inn Sikeston
From$75
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Holiday Inn Express & Suites Sikeston : 115 Hospitality Dr.
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863 Front Desk: 15734759522
115 Hospitality Dr., Sikeston, MO 63801 ~24.54 miles west of Cairo
  • Economical property
More Photos Exterior of Holiday Inn Express & Suites Sikeston
From$60
Very Good 4.5 /5Latest Reviews CallBookMore Details
Days Inn Sikeston
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863
1330 South Main St., Sikeston, MO 63801 ~24.66 miles west of Cairo
  • 2-star hotel
  • Check-in time: 11:00 AM
More Photos Image of Days Inn Sikeston
From$60
Poor 2.0 /5Review Score CallBookMore Details
Residence Inn : 3900 Coleman Crossing Circle
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 12704443966
3900 Coleman Crossing Circle, Paducah, KY 42001 ~25.70 miles east of Cairo
  • Three Star Suburban hotel
  • Free breakfast available
  • World class service
  • Two weeks straight
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From$89
Very Good 4.5 /5Review Score CallBookMore Details
Pear Tree Inn Paducah in Paducah
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 18004361126
5006 Hinkleville Rd., Paducah, KY 42001 ~25.80 miles east of Cairo
  • Cheap Suburban hotel
  • Check-in time: 3:00 PM
  • Pleasant entrance area
  • Excellent value
More Photos Exterior of Pear Tree Inn Paducah
From$62
Very Good 4.0 /5Review Score CallBookMore Details
Baymont Inn & Suites Metropolis Il in Metropolis
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 16185245678
203 East Front St., Metropolis, IL 62960 ~26.33 miles east of Cairo
  • 2-star Riverfront hotel
  • Gym / Fitness Center Available
  • Wifi didn't work
  • Friendly maids
More Photos Exterior of Baymont Inn & Suites Metropolis Il
From$35
Average 3.5 /5Read Reviews CallBookMore Details
Baymont Inn & Suites Paducah in Paducah
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 12704434343
5300 Old Cairo Rd., Paducah, KY 42001 ~27.67 miles east of Cairo
  • Midscale hotel
  • 3 floors in hotel
More Photos Photo of Baymont Inn & Suites Paducah
From$40
Average 3.5 /5Read Reviews CallBookMore Details
Drury Suites Paducah
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 18004361126
2930 James Sanders Blvd., Paducah, KY 42001 ~27.73 miles east of Cairo
  • Affordable Suburban hotel
  • Hotel has 6 floors
  • Included hot breakfast
  • Great shopping
More Photos Image of Drury Suites Paducah
From$90
Very Good 4.5 /5Review Score CallBookMore Details
Quality Suites
+1-866-221-8581

How should we direct your call?

New Reservations: +1-866-221-8581 Group Sales: +1-888-494-8863 Front Desk: 12704422080
2880 James Sanders Blvd., Paducah, KY 42001 ~27.76 miles east of Cairo
  • 3-star Highway property
  • Gym / Fitness Center Available
More Photos Photo of Quality Suites
From$80
Very Good 4.0 /5Read Reviews CallBookMore Details
Country Inn & Suites Lithia Springs - Lithia Springs
+1-866-429-5787

How should we direct your call?

New Reservations: +1-866-429-5787 Group Sales: +1-888-494-8863 Front Desk: 18004564000
960 West Pointe Court, Lithia Springs, GA 30122 ~27.83 miles east of Cairo
  • Mid-scale Rural property
  • Hotel has 55 suites
More Photos Exterior of Country Inn & Suites Lithia Springs
From$70
Poor 2.5 /5Reviews CallBookMore Details
Country Inn & Suites - Paducah
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 12704422201
145 Mcbride Lane, Paducah, KY 42001 ~27.83 miles east of Cairo
  • 3 star Highway hotel
  • Check-in time: 4pm
More Photos Photo of Country Inn & Suites
From$65
Very Good 4.0 /5Guest Reviews CallBookMore Details
Super 8 Paducah Ky
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 2704423334
5001 Hinkleville Rd., Paducah, KY 42001 ~27.85 miles east of Cairo
  • 2 star property
More Photos Photo of Super 8 Paducah Ky
From$60
Average 3.5 /5Review Score CallBookMore Details
Thrifty Inn : 5004 Hinkleville Rd.
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 18004459410
5004 Hinkleville Rd., Paducah, KY 42001 ~27.85 miles east of Cairo
  • Two star hotel
  • 4 floors in hotel
  • Most guests criticized the unstylish hotel
  • Accessible parking
More Photos Image of Thrifty Inn
From$60
CallBookMore Details
La Quinta Inn & Suites : 3960 Coleman Crossing Circle
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 12704434800
3960 Coleman Crossing Circle, Paducah, KY 42001 ~27.93 miles east of Cairo
  • Mid-scale Highway property
  • Hotel has a green policy See policy
More Photos Image of La Quinta Inn & Suites
From$89
Very Good 4.5 /5Hotel Reviews CallBookMore Details
Candlewood Suites
+1-888-283-3404

How should we direct your call?

New Reservations: +1-888-283-3404 Group Sales: +1-888-494-8863 Front Desk: 12704423969
3940 Coleman Crossing Circle, Paducah, KY 42001 ~27.94 miles east of Cairo
  • Inexpensive Rural hotel
  • 85 rooms in hotel
More Photos Image of Candlewood Suites
From$60
Very Good 4.0 /5Reviews CallBookMore Details
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