Star Rating
Hotel Name
Price Range (USD) to
Amenities
+ More

Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels/Accommodations

Country Hearth Inn & Suites Cayce / Columbia 3020 Charleston Highway, Cayce, SC 29033
Call Us
  • Two star property
More Photos hotel room
From$72 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in Cayce" Get Alexa Skill →
Knights Inn Columbia Airport/Cayce - Cayce 1987 Airport Blvd., Cayce, SC 29033
Call Us
  • Low-priced property
  • 2 floors in property
More Photos hotel room
From$63 total
Poor 2.0 /5 Review Score Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport 1935 Airport Blvd., Cayce, SC 29033
Call Us
  • Cheap Airport property
  • Check in time: 3PM
More Photos Image of Econo Lodge Inn & Suites Cayce I-26 Airport
From$82 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott : 613 Knox Abbott Dr. 613 Knox Abbott Dr., Cayce, NC 29033
Call Us
  • Mid-scale property
  • Check-in: 15:00
More Photos hotel room
From$88 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport in West Columbia 650 Cherokee Lane, West Columbia, SC 29169
Call Us
~1.52 miles west of Cayce
  • Two-star Airport hotel
  • Airport shuttle available
More Photos Exterior of Motel 6 West Columbia Sc Airport
From$72 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 West Columbia Sc in West Columbia 2200 Airport Blvd., West Columbia, SC 29170
Call Us
~1.66 miles west of Cayce
  • Two star property
  • Check in: 3:00 PM
More Photos hotel room
From$72 total
Average 3.0 /5 Review Score Call BookMore Details
Red Roof Inn Columbia, SC Airport in West Columbia 2204 Airport Blvd., West Columbia, SC 29170
Call Us
~1.70 miles west of Cayce
  • Two star Airport property
  • Check-in time: 3:00PM
More Photos Photo of Red Roof Inn Columbia, SC Airport
From$78 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Sleep Inn Airport - West Columbia 2208 Airport Blvd., West Columbia, SC 29170
Call Us
~1.74 miles west of Cayce
  • 2-star Airport property
  • Hotel has 5 floors
More Photos Image of Sleep Inn Airport
From$72 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Country Inn & Suites Columbia Airport 2245 Airport Blvd., Cayce, SC 29033
Call Us
  • Mid-scale Airport hotel
  • Airport shuttle provided
More Photos Image of Country Inn & Suites Columbia Airport
From$78 total
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport 110 Branch Rd., West Columbia, SC 29170
Call Us
~1.82 miles west of Cayce
  • Two star Airport property
  • Shuttle to airport available
More Photos Image of Days Inn & Suites by Wyndham Columbia Airport
From$72 total
Poor 2.0 /5 Recent Reviews Call BookMore Details
Clarion Inn Airport West Columbia : 29169 29169, West Columbia, SC 29169
Call Us
~2.17 miles north of Cayce
  • Mid-scale Airport hotel
  • Fitness + Health Center
More Photos Photo of Clarion Inn Airport West Columbia
From$96 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites 3020 Charleston Highway, West Columbia, SC 29172
Call Us
~2.40 miles south of Cayce
  • Affordable Airport property
  • Hotel has 57 rooms
More Photos Photo of Quality Inn & Suites
From$96 total
Average 3.0 /5 Review Score Call BookMore Details
Courtyard by Marriott Columbia Cayce 1125 Fort Congaree Trail, Cayce, SC 29033
Call Us
  • Three Star Highway property
  • 3 suites in property
More Photos Exterior of Courtyard by Marriott Columbia Cayce
From$118 total
Average 3.0 /5 Latest Reviews Call BookMore Details
More Homes & Apts at Booking.com

Book online or call +1-800-219-2797

Booking for Homes and Apartments
Go to BookingGo to Booking
Quality Inn Columbia Airport in West Columbia 2516 Augusta Rd., West Columbia, SC 29169 Website
Call Us
~2.53 miles northwest of Cayce
  • Economical Airport property
  • 82 rooms in hotel
More Photos Image of Quality Inn Columbia Airport
From$72 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Homewood Suites by Hilton Columbia Downtown in Columbia 400 Gervais St., Columbia, SC 29214
Call Us
~2.67 miles northeast of Cayce
  • Midscale hotel
More Photos hotel room
From$96 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in Cayce" Get Alexa Skill →
TRU by Hilton Columbia Downtown 400a Gervais St., Columbia, SC 29214
Call Us
~2.67 miles northeast of Cayce
  • Affordable property
  • Check-in: 3:00PM
More Photos hotel room
From$96 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Clarion Inn Columbia Airport 500 Chris Dr., West Columbia, SC 29169
Call Us
~2.67 miles northwest of Cayce
  • 3 star Airport hotel
  • 5 meeting rooms in hotel
More Photos Exterior of Clarion Inn Columbia Airport
From$62 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection in Columbia 621 South Assembly St., Columbia, SC 29201
Call Us
~2.80 miles east of Cayce
  • Low Cost Downtown hotel
  • Hotel has 3 floors
More Photos Exterior of Gallus Stadium Park Inn Ascend Hotel Collection
From$72 total
Average 3.0 /5 Latest Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista in Columbia 511 Lady St., Columbia, SC 29201
Call Us
~2.83 miles northeast of Cayce
  • 3-star Downtown hotel
  • 132 suites in property
More Photos Photo of SpringHill Suites by Marriott Columbia Downtown/The Vista
From$118 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC in Columbia 630 Assembly St., Columbia, SC 29201
Call Us
~2.95 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Check in: 4pm
More Photos Exterior of Courtyard by Marriott Columbia Downtown at USC
From$118 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District in Columbia 822 Gervais St., Columbia, SC 29201
Call Us
~3.00 miles northeast of Cayce
  • Affordable Downtown hotel
  • Free comp. breakfast
More Photos Photo of Hampton Inn Columbia-Downtown Historic District
From$150 total
Very Good 4.5 /5 Reviews Call BookMore Details
Hilton Columbia Center - Columbia 924 Senate St., Columbia, SC 29201
Call Us
~3.01 miles northeast of Cayce
  • High-end Downtown property
  • Check-in time: 4:00pm
More Photos Photo of Hilton Columbia Center
From$121 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista - Columbia 819 Gervais St., Columbia, SC 29201
Call Us
~3.02 miles northeast of Cayce
  • Affordable Downtown property
  • Fitness + Health Center
More Photos Photo of Hyatt Place Columbia / Downtown / The Vista
From$96 total
Average 3.0 /5 Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown 501 Taylor St., Columbia, SC 29201
Call Us
~3.05 miles north of Cayce
  • 3 star Downtown property
  • 83 sleeping rooms in hotel
More Photos Image of Fairfield Inn & Suites Columbia Downtown
From$154 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Aloft by Marriott Columbia Downtown 823 Lady St., Columbia, SC 29201
Call Us
~3.06 miles northeast of Cayce
  • 3 star Downtown hotel
  • Hotel has a green policy Read more
More Photos Photo of Aloft by Marriott Columbia Downtown
From$96 total
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih 901 Washington St., Columbia, SC 29201
Call Us
~3.18 miles northeast of Cayce
  • Midscale property
  • 105 rooms in property
More Photos hotel room
From$108 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista 1000 Lady St., Columbia, SC 29201 Website
Call Us
~3.18 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Hotel has 4 floors
More Photos Image of Cambria Hotel Columbia Downtown The Vista
From$118 total
Average 3.0 /5 Review Score Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel - Columbia 1913 Huger St., Columbia, SC 29201
Call Us
~3.26 miles north of Cayce
  • 3-star Downtown property
  • 5 floors in hotel
More Photos Image of Staybridge Suites Columbia An Ihg Hotel
From$130 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Moxy Columbia : 1200 Main St. 1200 Main St., Columbia, SC 29201
Call Us
~3.31 miles northeast of Cayce
  • 3 star Downtown property
  • 128 sleeping rooms in hotel
More Photos Photo of Moxy Columbia
From$96 total
Average 3.0 /5 Review Score Call BookMore Details
Microtel in Columbia 1301 Main St., Columbia, SC 29201
Call Us
~3.33 miles northeast of Cayce
  • 2 star Downtown property
  • 60 rooms in property
More Photos hotel room
From$54 total
Average 3.0 /5 Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel 1400 Main St., Columbia, SC 29201
Call Us
~3.43 miles northeast of Cayce
  • High-end Downtown property
  • Hotel has 17 floors
More Photos Image of Sheraton Columbia Downtown Hotel
From$154 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Columbia Downtown - Columbia 1233 Washington St., Columbia, SC 29201
Call Us
~3.47 miles northeast of Cayce
  • Midscale Downtown hotel
  • Check-in time: 12:00 PM
More Photos Photo of Holiday Inn Columbia Downtown
From$96 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Marriott Columbia 1200 Hampton St., Columbia, SC 29201
Call Us
~3.48 miles northeast of Cayce
  • Four star Downtown property
  • 15 meeting rooms in property
More Photos Exterior of Marriott Columbia
From$112 total
Very Good 4.0 /5 Review Score Call BookMore Details
Masters Inn Columbia I-26 : 2125 Commerce Dr. 2125 Commerce Dr., Cayce, NC 29033
Call Us
  • Two star property
  • Check in: 15:00
More Photos Image of Masters Inn Columbia I-26
From$72 total
Poor 2.0 /5 Latest Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone 180 Stoneridge Dr., Columbia, SC 29210
Call Us
~3.54 miles north of Cayce
  • Cheap Downtown hotel
  • 72 sleeping rooms in hotel
More Photos Exterior of Extended Stay America Suites Columbia Greystone
From$42 total
Average 3.0 /5 Reviews Call BookMore Details
Hotel Trundle : 1224 Taylor St. 1224 Taylor St., Columbia, SC 29201
Call Us
~3.56 miles northeast of Cayce
  • Three Star Downtown hotel
  • Hotel has a green policy See policy
More Photos Photo of Hotel Trundle
From$178 total
Very Good 4.0 /5 Reviews Call BookMore Details
Graduate by Hilton Columbia SC - Columbia 1619 Pendleton St., Columbia, SC 29201
Call Us
~3.57 miles northeast of Cayce
  • High-end Downtown hotel
  • Free complimentary breakfast
More Photos Image of Graduate by Hilton Columbia SC
From$154 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 450 Gracern Rd., Columbia, SC 29210
Call Us
~3.57 miles north of Cayce
  • Low Cost property
  • 120 rooms in hotel
More Photos Image of Extended Stay America Suites Columbia West Interstate 126
From$32 total
Poor 2.0 /5 Review Score Call BookMore Details
Hampton Inn I 26 Airport : 1094 Chris Dr. 1094 Chris Dr., West Columbia, SC 29169
Call Us
~3.61 miles northwest of Cayce
  • Affordable Highway hotel
  • Free breakfast
More Photos Image of Hampton Inn I 26 Airport
From$96 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Embassy Suites Columbia : 200 Stoneridge Dr. 200 Stoneridge Dr., Columbia, SC 29210
Call Us
~3.65 miles north of Cayce
  • Affordable Suburban property
  • Shuttle to airport available
More Photos Exterior of Embassy Suites Columbia
From$141 total
Very Good 4.0 /5 Review Score Call BookMore Details
TRU by Hilton Columbia Greystone - Columbia 185 Stoneridge Dr., Columbia, SC 29210
Call Us
~3.66 miles north of Cayce
  • Three Star Downtown property
  • Check in time: 3:00pm
More Photos Exterior of TRU by Hilton Columbia Greystone
From$96 total
Average 3.0 /5 Reviews Call BookMore Details
Carolina University Inn in Columbia 1615 Gervais St., Columbia, SC 29201
Call Us
~3.66 miles northeast of Cayce
  • 3 star Downtown hotel
  • Check-in time: 3:00 PM
More Photos Photo of Carolina University Inn
From$70 total
Poor 2.5 /5 Hotel Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown 1609 Gervais St., Columbia, SC 29201
Call Us
~3.67 miles northeast of Cayce
  • 3-star hotel
  • Hotel has 100 rooms
More Photos Exterior of Home2 Suites by Hilton Columbia Downtown
From$96 total
Average 3.0 /5 Review Score Call BookMore Details
Hilton Garden Inn Columbia Airport 110 Mcswain Dr., West Columbia, SC 29169
Call Us
~3.76 miles northwest of Cayce
  • Affordable Airport property
  • 122 rooms in property
More Photos Photo of Hilton Garden Inn Columbia Airport
From$114 total
Very Good 4.0 /5 Review Score Call BookMore Details
Oyo Hotel Columbia Sc West 114 Mcswain Dr., Columbia, SC 29169
Call Us
~3.86 miles northwest of Cayce
  • Affordable hotel
  • 40 rooms in property
More Photos Image of Oyo Hotel Columbia Sc West
From$108 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Homewood Suites by Hilton Columbia : 230 Greystone Blvd. 230 Greystone Blvd., Columbia, SC 29210
Call Us
~3.91 miles north of Cayce
  • Midscale Downtown property
  • 6 meeting rooms in property
More Photos Image of Homewood Suites by Hilton Columbia
From$90 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington in West Columbia 122 Mathias Rd., West Columbia, SC 29169
Call Us
~4.07 miles northwest of Cayce
  • Midscale Highway property
  • 108 suites in hotel
More Photos Image of Residence Inn by Marriott Columbia West / Lexington
From$90 total
Average 3.0 /5 Read Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington in West Columbia 2915 Sunset Blvd., West Columbia, SC 29169
Call Us
~4.18 miles northwest of Cayce
  • Midscale property
  • Hotel has 111 suites
More Photos Photo of Towneplace Suites Columbia West / Lexington
From$90 total
Very Good 4.0 /5 Review Score Call BookMore Details
Comfort Inn Columbia 911 Bush River Rd., Columbia, SC 29210
Call Us
~5.07 miles north of Cayce
  • Midscale Highway property
  • Fitness / Gym is on-site
More Photos Image of Comfort Inn Columbia
From$74 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Columbia in Columbia 1144 Bush River Rd., Columbia, SC 29210
Call Us
~5.13 miles northwest of Cayce
  • Cheap hotel
More Photos Exterior of Days Inn by Wyndham Columbia
From$72 total
Not Good 1.0 /5 Hotel Reviews Call BookMore Details

Next: See My Cayce Hotels with Pricing

Graph: Upcoming 20 Days of Cayce Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cayce, SC discounts available. The chart reflects the cheapest Cayce hotel for each day and each star rating category.

FAQs about hotels in Cayce

What are the most favored hotels in Cayce?

Country Inn & Suites Columbia Airport, Hampton Inn Columbia-Downtown Historic District and Econo Lodge Inn & Suites Cayce I-26 Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Cayce?

Hilton Columbia Center, Sheraton Columbia Downtown Hotel and Marriott Columbia are the top 3 luxury hotels near Cayce city center.

What hotels are closest to the city center of Cayce?

Country Hearth Inn & Suites Cayce, Knights Inn Columbia Airport, and Econo Lodge Inn & Suites Cayce I-26 Airport are the properties closest to Cayce city center.

What are the best independent hotels in Cayce?

Hotel Trundle, Oyo Hotel Columbia Sc West and Carolina University Inn are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Cayce?

SpringHill Suites by Marriott Columbia Downtown, Courtyard by Marriott Columbia Downtown at USC and Marriott Columbia are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Cayce?

Econo Lodge Inn & Suites Cayce I-26 Airport, Sleep Inn Airport and Clarion Inn Columbia Airport are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Cayce?

Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih, Staybridge Suites Columbia An Ihg Hotel and Holiday Inn Columbia Downtown are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
The average traveler rating of the city of Cayce, SC shown above is 4.8 out of 5 based on 5 reviews
Back to Top