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Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia 3020 Charleston Highway, Cayce, SC 29033
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  • Two star hotel
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From$60
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Knights Inn Columbia Airport/Cayce in Cayce 1987 Airport Blvd., Cayce, SC 29033
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  • Low priced hotel
  • 2 floors in hotel
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From$53
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Econo Lodge Inn & Suites Cayce I-26 Airport : 1935 Airport Blvd. 1935 Airport Blvd., Cayce, SC 29033
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  • 2-star Airport hotel
  • Hotel has a green policy Read more
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From$69
Very Good 4.0 /5 Review Score Call BookMore Details
Masters Inn Columbia Knox Abbott - Cayce 613 Knox Abbott Dr., Cayce, NC 29033
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  • Three Star hotel
  • Check-in: 15:00
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From$74
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Motel 6 West Columbia Sc Airport in West Columbia 650 Cherokee Lane, West Columbia, SC 29169
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~1.52 miles west of Cayce
  • Two star Airport property
  • Airport shuttle provided
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From$60
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Motel 6 West Columbia Sc - West Columbia 2200 Airport Blvd., West Columbia, SC 29170
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~1.66 miles west of Cayce
  • Two-star hotel
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From$60
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Red Roof Inn Columbia, SC Airport : 2204 Airport Blvd. 2204 Airport Blvd., West Columbia, SC 29170
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~1.70 miles west of Cayce
  • Economy Airport property
  • 64 sleeping rooms in hotel
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From$65
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Sleep Inn Airport - West Columbia 2208 Airport Blvd., West Columbia, SC 29170
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~1.74 miles west of Cayce
  • Inexpensive Airport hotel
  • Comp. Breakfast
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From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Country Inn & Suites Columbia Airport 2245 Airport Blvd., Cayce, SC 29033
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  • Affordable Airport property
  • 3 floors in hotel
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From$65
Very Good 4.5 /5 Review Score Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport - West Columbia 110 Branch Rd., West Columbia, SC 29170
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~1.82 miles west of Cayce
  • Two-star Airport hotel
  • Shuttle from airport available
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From$60
Poor 2.0 /5 Review Score Call BookMore Details
Clarion Inn Airport West Columbia - West Columbia 29169, West Columbia, SC 29169
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~2.17 miles north of Cayce
  • Three Star Airport property
  • 5 meeting rooms in property
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From$80
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Quality Inn & Suites - West Columbia 3020 Charleston Highway, West Columbia, SC 29172
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~2.40 miles south of Cayce
  • 3-star Airport hotel
  • 57 rooms in hotel
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From$80
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Courtyard by Marriott Columbia Cayce 1125 Fort Congaree Trail, Cayce, SC 29033
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  • Midscale Highway hotel
  • Hotel has 3 suites
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From$99
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Quality Inn Columbia Airport in West Columbia 2516 Augusta Rd., West Columbia, SC 29169 Website
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~2.53 miles northwest of Cayce
  • Cheap Airport hotel
  • Hotel has 82 rooms
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From$60
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Clarion Inn Columbia Airport in West Columbia 500 Chris Dr., West Columbia, SC 29169
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~2.67 miles northwest of Cayce
  • Affordable Airport hotel
  • 142 rooms in hotel
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From$52
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Gallus Stadium Park Inn Ascend Hotel Collection 621 South Assembly St., Columbia, SC 29201
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~2.80 miles east of Cayce
  • 2 star Downtown property
  • Free complimentary breakfast
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From$60
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SpringHill Suites by Marriott Columbia Downtown/The Vista 511 Lady St., Columbia, SC 29201
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~2.83 miles northeast of Cayce
  • Mid-scale Downtown property
  • Fitness / Gym is on-site
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From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC : 630 Assembly St. 630 Assembly St., Columbia, SC 29201
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~2.95 miles northeast of Cayce
  • Affordable Downtown hotel
  • Shuttle to airport available
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From$99
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Hampton Inn Columbia-Downtown Historic District : 822 Gervais St. 822 Gervais St., Columbia, SC 29201
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~3.00 miles northeast of Cayce
  • 3 star Downtown property
  • Free comp. breakfast
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From$125
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Hilton Columbia Center 924 Senate St., Columbia, SC 29201
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~3.01 miles northeast of Cayce
  • Four star Downtown property
  • 8 floors in property
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From$101
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Hyatt Place Columbia / Downtown / The Vista in Columbia 819 Gervais St., Columbia, SC 29201
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~3.02 miles northeast of Cayce
  • 3 star Downtown property
  • 6 floors in property
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From$80
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Fairfield Inn & Suites Columbia Downtown : 501 Taylor St. 501 Taylor St., Columbia, SC 29201
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~3.05 miles north of Cayce
  • Three Star Downtown property
  • 4 floors in hotel
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From$129
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Aloft Columbia Downtown 823 Lady St., Columbia, SC 29201
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~3.06 miles northeast of Cayce
  • Midscale Downtown property
  • Hotel has an eco-friendly policy See more
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From$80
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Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih 901 Washington St., Columbia, SC 29201
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~3.18 miles northeast of Cayce
  • Affordable property
  • 105 rooms in hotel
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From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista : 1000 Lady St. 1000 Lady St., Columbia, SC 29201 Website
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~3.18 miles northeast of Cayce
  • 3 star Downtown hotel
  • 4 floors in hotel
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From$99
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Staybridge Suites Columbia An Ihg Hotel : 1913 Huger St. 1913 Huger St., Columbia, SC 29201
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~3.26 miles north of Cayce
  • Mid-scale Downtown property
  • 5 floors in property
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From$109
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Moxy Columbia Downtown : 1200 Main St. 1200 Main St., Columbia, SC 29201
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~3.31 miles northeast of Cayce
  • Expensive hotel
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From$125
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Microtel in Columbia 1301 Main St., Columbia, SC 29201
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~3.33 miles northeast of Cayce
  • Two star Downtown hotel
  • Check in time: 3:00 PM
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From$45
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Sheraton Columbia Downtown Hotel - Columbia 1400 Main St., Columbia, SC 29201
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~3.43 miles northeast of Cayce
  • Four-star Downtown property
  • Check-in time: 3:00pm
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From$129
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Holiday Inn Columbia Downtown in Columbia 1233 Washington St., Columbia, SC 29201
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~3.47 miles northeast of Cayce
  • Affordable Downtown hotel
  • 90 rooms in property
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From$80
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Marriott Columbia 1200 Hampton St., Columbia, SC 29201
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~3.48 miles northeast of Cayce
  • Four star Downtown hotel
  • 300 sleeping rooms in hotel
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From$94
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Masters Inn Columbia I-26 2125 Commerce Dr., Cayce, NC 29033
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  • Inexpensive hotel
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From$60
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Extended Stay America Suites Columbia Greystone : 180 Stoneridge Dr. 180 Stoneridge Dr., Columbia, SC 29210
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~3.54 miles north of Cayce
  • Cheap Downtown hotel
  • 72 sleeping rooms in hotel
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From$35
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Hotel Trundle - Columbia 1224 Taylor St., Columbia, SC 29201
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~3.56 miles northeast of Cayce
  • Midscale Downtown property
  • 41 sleeping rooms in hotel
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From$149
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Graduate by Hilton Columbia SC - Columbia 1619 Pendleton St., Columbia, SC 29201
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~3.57 miles northeast of Cayce
  • Four star Downtown hotel
  • Free complimentary breakfast
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From$129
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Extended Stay America Suites Columbia West Interstate 126 450 Gracern Rd., Columbia, SC 29210
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~3.57 miles north of Cayce
  • 2-star property
  • 120 rooms in property
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From$27
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Hampton Inn I 26 Airport - West Columbia 1094 Chris Dr., West Columbia, SC 29169
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~3.61 miles northwest of Cayce
  • Mid-scale Highway property
  • Check in: 3:00PM
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From$80
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TRU Columbia Greystone - Columbia 183 Stoneridge Dr., Columbia, SC 29210
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~3.64 miles north of Cayce
  • Midscale Downtown property
  • 117 rooms in hotel
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From$90
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Embassy Suites Columbia : 200 Stoneridge Dr. 200 Stoneridge Dr., Columbia, SC 29210
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~3.65 miles north of Cayce
  • 3 star Suburban property
  • Free breakfast available
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From$118
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TRU by Hilton Columbia Greystone 185 Stoneridge Dr., Columbia, SC 29210
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~3.66 miles north of Cayce
  • Affordable Downtown hotel
  • Free complimentary breakfast
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From$80
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Carolina University Inn 1615 Gervais St., Columbia, SC 29201
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~3.66 miles northeast of Cayce
  • 3 star Downtown property
  • 4 conference rooms in property
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From$59
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Home2 Suites by Hilton Columbia Downtown - Columbia 1609 Gervais St., Columbia, SC 29201
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~3.67 miles northeast of Cayce
  • 3 star property
  • Check-in time: 15:00
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From$80
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Hilton Garden Inn Columbia Airport 110 Mcswain Dr., West Columbia, SC 29169
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~3.76 miles northwest of Cayce
  • 3 star Airport hotel
  • Check in: 3:00 PM
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From$95
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Oyo Hotel Columbia Sc West - Columbia 114 Mcswain Dr., Columbia, SC 29169
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~3.86 miles northwest of Cayce
  • Three Star property
  • Check in: 15:00
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From$90
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Homewood Suites by Hilton Columbia : 230 Greystone Blvd. 230 Greystone Blvd., Columbia, SC 29210
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~3.91 miles north of Cayce
  • 3-star Downtown property
  • Access to gym on-site
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From$75
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Residence Inn by Marriott Columbia West / Lexington - West Columbia 122 Mathias Rd., West Columbia, SC 29169
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~4.07 miles northwest of Cayce
  • Affordable Highway property
  • Hotel has 108 suites
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From$75
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Towneplace Suites Columbia West / Lexington : 2915 Sunset Blvd. 2915 Sunset Blvd., West Columbia, SC 29169
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~4.18 miles northwest of Cayce
  • Three Star hotel
  • 111 rooms in hotel
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From$75
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Comfort Inn Columbia - Columbia 911 Bush River Rd., Columbia, SC 29210
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~5.07 miles north of Cayce
  • Mid-scale Highway property
  • Airport shuttle available
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From$62
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Days Inn by Wyndham Columbia : 1144 Bush River Rd. 1144 Bush River Rd., Columbia, SC 29210
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~5.13 miles northwest of Cayce
  • Low Cost property
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From$60
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Hawthorn Suites by Wyndham Columbia 200 Zimalcrest Dr., Columbia, SC 29210
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~5.29 miles northwest of Cayce
  • Affordable Suburban property
  • Fitness + Health Center
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From$49
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Next: See My Cayce Hotels with Pricing

Graph: Upcoming 20 Days of Cayce Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cayce, SC discounts available. The chart reflects the cheapest Cayce hotel for each day and each star rating category.

FAQs about hotels in Cayce

What are the most favored hotels in Cayce?

Country Inn & Suites Columbia Airport, Hampton Inn Columbia-Downtown Historic District and Econo Lodge Inn & Suites Cayce I-26 Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Cayce?

Hilton Columbia Center, Moxy Columbia Downtown and Sheraton Columbia Downtown Hotel are the top 3 luxury hotels near Cayce city center.

What hotels are closest to the city center of Cayce?

Country Hearth Inn & Suites Cayce, Knights Inn Columbia Airport, and Econo Lodge Inn & Suites Cayce I-26 Airport are the properties closest to Cayce city center.

What are the best independent hotels in Cayce?

Hotel Trundle, Oyo Hotel Columbia Sc West and Carolina University Inn are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Cayce?

SpringHill Suites by Marriott Columbia Downtown, Courtyard by Marriott Columbia Downtown at USC and Marriott Columbia are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Cayce?

Econo Lodge Inn & Suites Cayce I-26 Airport, Sleep Inn Airport and Clarion Inn Columbia Airport are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Cayce?

Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih, Staybridge Suites Columbia An Ihg Hotel and Holiday Inn Columbia Downtown are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
The average traveler rating of the city of Cayce, SC shown above is 4.8 out of 5 based on 5 reviews
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