Hotels in 29221 - Columbia SC

Only hotels in 29221 zip code are listed below. Search for cheap and discount hotel rates in Columbia, SC for your upcoming leisure or conference / group travel. We list the best 29221 hotels and motels so you can review the Columbia hotel list below to find the perfect lodging. Hotels in Richland county and area code 803 are also listed.

Star Rating
Hotel Name
Price Range (USD)to
Amenities

29221 Hotels/Motels & Accommodations

Econo Lodge & Conference Center
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863
773 St.andrews Rd., Columbia, SC 29210 ~0.46 miles west of 29221
  • 2 star Highway property
  • 64 rooms in property
More Photoshotel room
From$39
Poor 2.0 /5Read Reviews Call
Motel 6 in Columbia
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863 Front Desk: 18037989210
1776 Burning Tree Rd., Columbia, SC 29210 ~0.52 miles west of 29221
  • Cheap Highway property
  • Check in time: 7:00 am
More Photos Image of Motel 6
From$75
Poor 2.0 /5Recent Reviews Call
Red Roof Inn
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 18037989220
10 Berryhill Rd., Columbia, SC 29210 ~0.68 miles southwest of 29221
  • Inexpensive Suburban hotel
  • Check in: 3:00 PM
More Photos Photo of Red Roof Inn
From$55
Poor 2.5 /5Reviews Call
Baymont Inn & Suites Columbia Northwest in Columbia
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 18037312300
347 Zimalcrest Dr., Columbia, SC 29210 ~1.03 miles south of 29221
  • Affordable Highway property
  • Free complimentary breakfast
More Photos Photo of Baymont Inn & Suites Columbia Northwest
From$59
Very Good 4.0 /5Recent Reviews Call
Sleep Inn Columbia Northwest - Columbia
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 18037319999
1901 Rockland Rd., Columbia, SC 29210 ~1.13 miles south of 29221
  • 3 star property
  • 4 floors in hotel
More Photos Image of Sleep Inn Columbia Northwest
From$59
Very Good 4.0 /5Review Score Call
Quality Inn
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863
1335 Garner Lane, Columbia, SC 29210 ~1.17 miles east of 29221
  • Midscale Highway property
  • 88 rooms in hotel
More Photos Image of Quality Inn
From$59
Poor 2.5 /5Hotel Reviews Call
Hawthorn Suites by Wyndham Columbia in Columbia
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863 Front Desk: 18037727200
200 Zimalcrest Dr., Columbia, SC 29210 ~1.18 miles south of 29221
  • Midscale Suburban property
  • Free complimentary breakfast
More Photos Photo of Hawthorn Suites by Wyndham Columbia
From$55
Poor 2.5 /5Recent Reviews Call
Ramada Limited
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 18037319997
1315 Garner Lane, Columbia, SC 29210 ~1.21 miles southeast of 29221
  • 2 star Highway property
  • Comp. Breakfast
More Photos Photo of Ramada Limited
From$59
Average 3.5 /5Review Score Call
Knights Inn Columbia Sc : 1803 Bush River Rd.
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863
1803 Bush River Rd., Columbia, SC 29210 ~1.26 miles south of 29221
  • Two star Downtown hotel
More Photos Photo of Knights Inn Columbia Sc
From$25
Poor 2.0 /5Latest Reviews Call
Comfort Inn Columbia
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 18037985101
911 Bush River Rd., Columbia, SC 29210 ~1.31 miles south of 29221
  • Three Star Highway property
  • Hotel has 6 suites
More Photos Photo of Comfort Inn Columbia
From$69
Very Good 4.5 /5Hotel Reviews Call
Best Western Executive Inn & Suites - Columbia
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863
1720 Bush River Rd., Columbia, SC 29210 ~1.32 miles south of 29221
  • Affordable Suburban property
  • Hotel has 23 suites
More Photos Image of Best Western Executive Inn & Suites
From$70
Very Good 4.0 /5Recent Reviews Call
Doubletree by Hilton Columbia Sc in Columbia
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 18037440142
2100 Bush River Rd., Columbia, SC 29223 ~1.39 miles southwest of 29221
  • Midscale Suburban property
  • Fitness / Gym is on-site
More Photos Image of Doubletree by Hilton Columbia Sc
From$79
Very Good 4.0 /5Recent Reviews Call
Quality Inn & Suites
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 18037989665
2210 Bush River Rd., Columbia, SC 29210 ~1.47 miles southwest of 29221
  • Economy Suburban property
  • Free breakfast available
More Photos Photo of Quality Inn & Suites
From$59
Average 3.0 /5Reviews Call
Quality Inn Harbison Area
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863
499 Piney Grove Rd., Columbia, SC 29210 ~2.23 miles northwest of 29221
  • Low-priced Highway property
  • 5 suites in hotel
More Photos Exterior of Quality Inn Harbison Area
From$49
Poor 2.5 /5Reviews Call
Country Inn & Suites Columbia at Harbison Sc in Columbia
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 18033914100
414 Piney Grove Rd., Columbia, SC 29210 ~2.50 miles west of 29221
  • Mid-scale Lake hotel
  • Access to gym on-site
More Photos Image of Country Inn & Suites Columbia at Harbison Sc
From$59
Average 3.5 /5Read Reviews Call
Microtel Inn & Suites
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863
411 Piney Grove Rd., Columbia, SC 29210 ~2.54 miles northwest of 29221
  • Low Cost Suburban hotel
  • Free breakfast available
More Photos Image of Microtel Inn & Suites
From$52
Poor 2.5 /5Review Score Call
Homewood Suites by Hilton of Columbia - Columbia
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863
230 Greystone Blvd., Columbia, SC 29210 ~2.69 miles southeast of 29221
  • 3-star Downtown property
  • 3 meeting rooms in hotel
More Photos Image of Homewood Suites by Hilton of Columbia
From$89
Very Good 4.5 /5Reviews Call
Embassy Suites Columbia Greystone - Columbia
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 18032528700
200 Stoneridge Dr., Columbia, SC 29210 ~2.94 miles southeast of 29221
  • 3 star Suburban property
  • Has environment-friendly policy See policy
More Photos Exterior of Embassy Suites Columbia Greystone
From$119
Very Good 4.0 /5Hotel Reviews Call
Hampton Inn Harbison - Columbia
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 18037496999
101 Woodcross Dr., Columbia, SC 29212 ~2.96 miles northwest of 29221
  • 3 star Highway hotel
  • Free comp. breakfast
More Photos Exterior of Hampton Inn Harbison
From$95
Very Good 4.5 /5Hotel Reviews Call
Extended Stay America Columbia West
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863
450 Gracern Rd., Columbia, SC 29210 ~2.98 miles southeast of 29221
  • Economical property
  • Check-in time: 3:00pm
More Photos Exterior of Extended Stay America Columbia West
From$27
Poor 2.5 /5Reviews Call
Holiday Inn & Suites Columbia Airport
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863 Front Desk: 18033914000
110 Mcswain Dr., West Columbia, SC 29169 ~3.05 miles south of 29221
  • 3-star Airport property
  • 7 conference rooms in property
More Photos Photo of Holiday Inn & Suites Columbia Airport
From$93
Very Good 4.0 /5Review Score Call
Comfort Suites Harbison
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 18034074444
750 Saturn Pkwy., Columbia, SC 29212 ~3.10 miles northwest of 29221
  • Three Star Highway property
  • Free breakfast
More Photos Photo of Comfort Suites Harbison
From$75
Very Good 4.0 /5Review Score Call
Studio Plus Columbia West in Columbia
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863
180 Stoneridge Dr., Columbia, SC 29210 ~3.14 miles southeast of 29221
  • 2 star Downtown property
  • Hotel has 72 rooms
More Photos hotel room
From$35
Poor 2.5 /5Review Score Call
Hampton Inn
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 18037918940
1094 Chris Dr., West Columbia, SC 29169 ~3.21 miles south of 29221
  • 3-star Highway property
  • Shuttle from airport available
More Photos Exterior of Hampton Inn
From$79
Very Good 4.0 /5Guest Reviews Call
Suburban Extended Stay Hotel - Columbia
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 18037797000
150 Stoneridge Dr., Columbia, SC 29210 ~3.24 miles southeast of 29221
  • 2-star Downtown property
  • Gym is available on property
More Photos Photo of Suburban Extended Stay Hotel
From$45
Average 3.0 /5Guest Reviews Call
Lexington Wingate by Wyndham in Lexington
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 8039575000
108 Saluda Pointe Court, Lexington, SC 29072 ~3.45 miles southwest of 29221
  • Affordable Suburban hotel
  • Hotel has 9 suites
More Photos Photo of Lexington Wingate by Wyndham
From$89
Very Good 4.5 /5Read Reviews Call
Wingate by Wyndham Harbison
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 18034076166
217 Lanneau Court, Columbia, SC 29212 ~3.47 miles northwest of 29221
  • Midscale Suburban property
  • Free complimentary breakfast
More Photos Exterior of Wingate by Wyndham Harbison
From$65
Very Good 4.0 /5Guest Reviews Call
Holiday Inn Express Harbison in Columbia
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863 Front Desk: 18037322229
211 Lanneau Court, Columbia, SC 29212 ~3.53 miles northwest of 29221
  • 3 star hotel
  • 82 rooms in property
More Photos Photo of Holiday Inn Express Harbison
From$74
Very Good 4.0 /5Read Reviews Call
Hilton Garden Inn Columbia / Harbison - Columbia
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 18034076640
434 Columbiana Dr., Columbia, SC 29212 ~3.72 miles northwest of 29221
  • 3 star Suburban hotel
  • Check in time: 12:00pm
More Photos Photo of Hilton Garden Inn Columbia / Harbison
From$89
Very Good 4.5 /5Latest Reviews Call
Fairfield Inn Columbia Northwest / Harbison - Columbia
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863 Front Desk: 18037324436
320 Columbiana Dr., Columbia, SC 29212 ~3.74 miles northwest of 29221
  • Economical Suburban hotel
  • 84 rooms in hotel
More Photos Exterior of Fairfield Inn Columbia Northwest / Harbison
From$60
Very Good 4.0 /5Recent Reviews Call
Intown Suites Columbia Northwest (Xcs) : 330 Columbiana Dr.
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 17707995090
330 Columbiana Dr., Columbia, SC 29212 ~3.80 miles northwest of 29221
  • 2 star hotel
More Photos Photo of Intown Suites Columbia Northwest (Xcs)
From$41
Call
Home Towne Suites - Columbia
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 18037819391
350 Columbiana Dr., Columbia, SC 29212 ~3.86 miles northwest of 29221
  • Three Star Suburban hotel
  • Hotel has 88 suites
More PhotosImage of Home Towne Suites
From$39
Average 3.0 /5Recent Reviews Call
Towneplace Suites Columbia Northwest / Harbison
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 18037497552
438 Columbiana Dr., Columbia, SC 29212 ~4.20 miles northwest of 29221
  • 3-star property
  • Free comp. breakfast
More Photos Image of Towneplace Suites Columbia Northwest / Harbison
From$99
Call
Extended Stay America Columbia Harbison in Irmo
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863
1170 Kinley Rd., Irmo, SC 29063 ~4.21 miles northwest of 29221
  • 3-star property
More Photos Image of Extended Stay America Columbia Harbison
From$69
Average 3.0 /5Latest Reviews Call
Hyatt Place Columbia / Harbison in Irmo
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863 Front Desk: 18034071560
1130 Kinley Rd., Irmo, SC 29063 ~4.33 miles northwest of 29221
  • 3-star Suburban hotel
  • 127 sleeping rooms in hotel
More Photos Image of Hyatt Place Columbia / Harbison
From$79
Very Good 4.0 /5Reviews Call
Staybridge Suites : 1913 Huger St.
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 18034515900
1913 Huger St., Columbia, SC 29201 ~4.37 miles southeast of 29221
  • 3 star Downtown hotel
  • Check-in time: 3:00PM
More Photos Image of Staybridge Suites
From$99
Very Good 4.5 /5Guest Reviews Call
Quality Inn in West Columbia
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863 Front Desk: 17324250239
2516 Augusta Rd., West Columbia, SC 29169 ~4.54 miles south of 29221
  • Low Cost Airport hotel
  • Free complimentary breakfast
More Photos Image of Quality Inn
From$44
Average 3.0 /5Hotel Reviews Call
Clarion Inn Airport : 500 Chris Dr.
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863
500 Chris Dr., Columbia, SC 29169 ~4.62 miles south of 29221
  • Three Star Airport property
  • 142 rooms in property
More Photos Image of Clarion Inn Airport
From$37
Average 3.5 /5Read Reviews Call
Residence Inn by Marriott Columbia Nw in Irmo
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 18037497575
944 Lake Murray Vblvd, Irmo, SC 29063 ~4.70 miles northwest of 29221
  • 3 star property
  • Free complimentary breakfast
More Photos Image of Residence Inn by Marriott Columbia Nw
From$99
Very Good 4.5 /5Recent Reviews Call
Holiday Inn Express Hotel & Suites Columbia in Columbia
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 18037444000
501 Taylor St., Columbia, SC 29201 ~4.70 miles southeast of 29221
  • 3-star Downtown property
  • Complimentary breakfast is offered
More Photos Exterior of Holiday Inn Express Hotel & Suites Columbia
From$97
Very Good 4.0 /5Read Reviews Call
Springhill Suites Columbia Downtown
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 8039782333
511 Lady St., Columbia, SC 29201 ~4.97 miles southeast of 29221
  • Affordable Downtown hotel
  • Complimentary breakfast is offered
More Photos Exterior of Springhill Suites Columbia Downtown
From$114
Very Good 4.5 /5Review Score Call
Aloft Columbia Downtown in Columbia
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863 Front Desk: 18038082150
823 Lady St., Columbia, SC 29201 ~5.12 miles southeast of 29221
  • High-end property
More Photos hotel room
From$75
Call
Columbia Marriott
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 8037446906
1200 Hampton St., Columbia, SC 29201 ~5.17 miles southeast of 29221
  • Expensive Downtown hotel
  • Check-in: 4:00pm
More Photoshotel room
From$94
Very Good 4.0 /5Latest Reviews Call
Hyatt Place Columbia Downtown Historic District : 819 Gervais St.
+1-800-230-4134

How should we direct your call?

New Reservations: +1-800-230-4134 Group Sales: +1-888-494-8863 Front Desk: 18039782013
819 Gervais St., Columbia, SC 29201 ~5.18 miles southeast of 29221
  • Mid-scale Downtown property
  • Check in: 3:00 PM
More Photos Photo of Hyatt Place Columbia Downtown Historic District
From$109
Very Good 4.5 /5Read Reviews Call
Hampton Inn Columbia Downtown Historic District
+1-800-997-5148

How should we direct your call?

New Reservations: +1-800-997-5148 Group Sales: +1-888-494-8863 Front Desk: 18032312000
822 Gervais St., Columbia, SC 29201 ~5.20 miles southeast of 29221
  • 3-star Downtown property
  • Hotel has 5 floors
More Photos Image of Hampton Inn Columbia Downtown Historic District
From$125
Very Good 4.5 /5Recent Reviews Call
Sheraton Columbia Downtown Hotel
+1-888-690-5247

How should we direct your call?

New Reservations: +1-888-690-5247 Group Sales: +1-888-494-8863 Front Desk: 18039881400
1400 Main St., Columbia, SC 29201 ~5.21 miles southeast of 29221
  • High end Downtown property
  • Check in time: 3:00pm
More Photos Exterior of Sheraton Columbia Downtown Hotel
From$98
Very Good 4.0 /5Hotel Reviews Call
Hilton Columbia Center
+1-888-305-3366

How should we direct your call?

New Reservations: +1-888-305-3366 Group Sales: +1-888-494-8863 Front Desk: 18037447800
924 Senate St., Columbia, SC 29201 ~5.33 miles southeast of 29221
  • Expensive Downtown hotel
  • 8 floors in hotel
More Photos Photo of Hilton Columbia Center
From$101
Very Good 4.5 /5Review Score Call
Carolina University Inn
+1-800-881-1523

How should we direct your call?

New Reservations: +1-800-881-1523 Group Sales: +1-888-494-8863 Front Desk: 18037718711
1615 Gervais St., Columbia, SC 29201 ~5.62 miles southeast of 29221
  • Midscale Downtown hotel
  • Hotel has 6 floors
More Photos Image of Carolina University Inn
From$59
Average 3.0 /5Review Score Call
Inn at Usc Wyndham Garden
+1-800-997-5149

How should we direct your call?

New Reservations: +1-800-997-5149 Group Sales: +1-888-494-8863
1619 Pendleton St., Columbia, SC 29201 ~5.76 miles southeast of 29221
  • Mid-scale Downtown hotel
  • Check in: 3:00pm
More Photos Image of Inn at Usc Wyndham Garden
From$109
Very Good 4.5 /5Latest Reviews Call
Courtyard Columbia Downtown at Usc
+1-888-690-5281

How should we direct your call?

New Reservations: +1-888-690-5281 Group Sales: +1-888-494-8863 Front Desk: 18037997800
630 Assembly St., Columbia, SC 29201 ~5.79 miles southeast of 29221
  • Midscale Downtown property
  • Check in: 4pm
More Photos Exterior of Courtyard Columbia Downtown at Usc
From$99
Very Good 4.0 /5Reviews Call

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