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Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels, Motels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia 3020 Charleston Highway, Cayce, SC 29033
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  • 2 star hotel
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From$72 total
Average 3.0 /5 Review Score Call BookMore Details
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Knights Inn Columbia Airport/Cayce in Cayce 1987 Airport Blvd., Cayce, SC 29033
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  • 2 star hotel
  • 117 sleeping rooms in hotel
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From$63 total
Poor 2.0 /5 Recent Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport 1935 Airport Blvd., Cayce, SC 29033
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  • Cheap Airport property
  • Free comp. breakfast
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From$82 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott : 613 Knox Abbott Dr. 613 Knox Abbott Dr., Cayce, NC 29033
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  • 3 star hotel
  • Check in: 15:00
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From$88 total
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Motel 6 West Columbia Sc Airport 650 Cherokee Lane, West Columbia, SC 29169
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~1.52 miles west of Cayce
  • Cheap Airport hotel
  • Hotel has 4 floors
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From$72 total
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Motel 6 West Columbia Sc 2200 Airport Blvd., West Columbia, SC 29170
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~1.66 miles west of Cayce
  • Economy hotel
  • Hotel has 2 floors
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From$72 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport : 2204 Airport Blvd. 2204 Airport Blvd., West Columbia, SC 29170
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~1.70 miles west of Cayce
  • 2-star Airport property
  • 64 rooms in hotel
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From$78 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Sleep Inn Airport 2208 Airport Blvd., West Columbia, SC 29170
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~1.74 miles west of Cayce
  • 2-star Airport hotel
  • Hotel has 69 rooms
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From$72 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Country Inn & Suites Columbia Airport in Cayce 2245 Airport Blvd., Cayce, SC 29033
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  • Mid-scale Airport hotel
  • 64 sleeping rooms in hotel
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From$78 total
Very Good 4.5 /5 Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport in West Columbia 110 Branch Rd., West Columbia, SC 29170
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~1.82 miles west of Cayce
  • Two star Airport hotel
  • Check in: 11:59 AM
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From$72 total
Poor 2.0 /5 Guest Reviews Call BookMore Details
Clarion Inn Airport West Columbia 29169, West Columbia, SC 29169
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~2.17 miles north of Cayce
  • 3-star Airport hotel
  • Check in time: 3:00pm
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From$96 total
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Quality Inn & Suites 3020 Charleston Highway, West Columbia, SC 29172
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~2.40 miles south of Cayce
  • Affordable Airport property
  • 57 rooms in property
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From$96 total
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Courtyard by Marriott Columbia Cayce 1125 Fort Congaree Trail, Cayce, SC 29033
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  • 3-star Highway hotel
  • 4 floors in hotel
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From$118 total
Average 3.0 /5 Latest Reviews Call BookMore Details
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Quality Inn Columbia Airport - West Columbia 2516 Augusta Rd., West Columbia, SC 29169 Website
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~2.53 miles northwest of Cayce
  • Inexpensive Airport property
  • Complimentary breakfast is offered
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From$72 total
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Homewood Suites by Hilton Columbia Downtown - Columbia 400 Gervais St., Columbia, SC 29214
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~2.67 miles northeast of Cayce
  • 3 star hotel
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From$96 total
Average 3.0 /5 Recent Reviews Call BookMore Details
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TRU by Hilton Columbia Downtown in Columbia 400a Gervais St., Columbia, SC 29214
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~2.67 miles northeast of Cayce
  • Affordable hotel
  • Check in: 3:00PM
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From$96 total
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Clarion Inn Columbia Airport : 500 Chris Dr. 500 Chris Dr., West Columbia, SC 29169
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~2.67 miles northwest of Cayce
  • Mid-scale Airport property
  • Free complimentary breakfast
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From$62 total
Very Good 4.0 /5 Review Score Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection : 621 South Assembly St. 621 South Assembly St., Columbia, SC 29201
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~2.80 miles east of Cayce
  • Cheap Downtown hotel
  • Complimentary breakfast is offered
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From$72 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista 511 Lady St., Columbia, SC 29201
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~2.83 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Hotel has 132 rooms
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From$118 total
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC : 630 Assembly St. 630 Assembly St., Columbia, SC 29201
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~2.95 miles northeast of Cayce
  • Three Star Downtown property
  • Hotel has 16 suites
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From$118 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District : 822 Gervais St. 822 Gervais St., Columbia, SC 29201
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~3.00 miles northeast of Cayce
  • Midscale Downtown property
  • 5 floors in hotel
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From$150 total
Very Good 4.5 /5 Read Reviews Call BookMore Details
Hilton Columbia Center 924 Senate St., Columbia, SC 29201
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~3.01 miles northeast of Cayce
  • Four star Downtown hotel
  • 222 rooms in hotel
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From$121 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista 819 Gervais St., Columbia, SC 29201
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~3.02 miles northeast of Cayce
  • 3-star Downtown hotel
  • Complimentary breakfast is offered
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From$96 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown 501 Taylor St., Columbia, SC 29201
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~3.05 miles north of Cayce
  • Affordable Downtown property
  • Comp. Breakfast
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From$154 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Aloft by Marriott Columbia Downtown 823 Lady St., Columbia, SC 29201
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~3.06 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Hotel has an eco-friendly policy Read more
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From$96 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih 901 Washington St., Columbia, SC 29201
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~3.18 miles northeast of Cayce
  • Three Star hotel
  • Check-in: 15:00
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From$108 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista in Columbia 1000 Lady St., Columbia, SC 29201 Website
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~3.18 miles northeast of Cayce
  • 3-star Downtown property
  • Check in time: 3:00 PM
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From$118 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel : 1913 Huger St. 1913 Huger St., Columbia, SC 29201
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~3.26 miles north of Cayce
  • Mid-scale Downtown hotel
  • 93 rooms in property
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From$130 total
Very Good 4.0 /5 Reviews Call BookMore Details
Moxy Columbia - Columbia 1200 Main St., Columbia, SC 29201
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~3.31 miles northeast of Cayce
  • Mid-scale Downtown property
  • Check-in time: 4:00 PM
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From$96 total
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Microtel 1301 Main St., Columbia, SC 29201
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~3.33 miles northeast of Cayce
  • Low priced Downtown hotel
  • 60 rooms in hotel
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From$54 total
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Sheraton Columbia Downtown Hotel - Columbia 1400 Main St., Columbia, SC 29201
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~3.43 miles northeast of Cayce
  • High-end Downtown property
  • Gym is available on property
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From$154 total
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Holiday Inn Columbia Downtown in Columbia 1233 Washington St., Columbia, SC 29201
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~3.47 miles northeast of Cayce
  • 3 star Downtown hotel
  • 10 floors in property
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From$96 total
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Marriott Columbia 1200 Hampton St., Columbia, SC 29201
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~3.48 miles northeast of Cayce
  • Four-star Downtown property
  • 300 sleeping rooms in hotel
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From$112 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Masters Inn Columbia I-26 in Cayce 2125 Commerce Dr., Cayce, NC 29033
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  • Two star hotel
  • Check-in time: 15:00
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From$72 total
Poor 2.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone 180 Stoneridge Dr., Columbia, SC 29210
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~3.54 miles north of Cayce
  • Low Cost Downtown hotel
  • 3 floors in property
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From$42 total
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Hotel Trundle - Columbia 1224 Taylor St., Columbia, SC 29201
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~3.56 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Has environment-friendly policy Read more
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From$178 total
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Graduate by Hilton Columbia SC 1619 Pendleton St., Columbia, SC 29201
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~3.57 miles northeast of Cayce
  • High end Downtown hotel
  • Hotel has 3 floors
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From$154 total
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Extended Stay America Suites Columbia West Interstate 126 450 Gracern Rd., Columbia, SC 29210
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~3.57 miles north of Cayce
  • 2-star hotel
  • Comp. Breakfast
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From$32 total
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn I 26 Airport : 1094 Chris Dr. 1094 Chris Dr., West Columbia, SC 29169
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~3.61 miles northwest of Cayce
  • Three Star Highway hotel
  • Check-in time: 3:00PM
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From$96 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Embassy Suites Columbia - Columbia 200 Stoneridge Dr., Columbia, SC 29210
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~3.65 miles north of Cayce
  • Three Star Suburban property
  • 7 floors in hotel
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From$141 total
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
TRU by Hilton Columbia Greystone 185 Stoneridge Dr., Columbia, SC 29210
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~3.66 miles north of Cayce
  • 3-star Downtown hotel
  • Check-in time: 3:00pm
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From$96 total
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Carolina University Inn - Columbia 1615 Gervais St., Columbia, SC 29201
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~3.66 miles northeast of Cayce
  • Mid-scale Downtown property
  • Hotel has an eco-friendly policy See policy
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From$70 total
Poor 2.5 /5 Latest Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown in Columbia 1609 Gervais St., Columbia, SC 29201
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~3.67 miles northeast of Cayce
  • Affordable hotel
  • Hotel has 6 floors
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From$96 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport in West Columbia 110 Mcswain Dr., West Columbia, SC 29169
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~3.76 miles northwest of Cayce
  • 3-star Airport hotel
  • 5 floors in property
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From$114 total
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Oyo Hotel Columbia Sc West 114 Mcswain Dr., Columbia, SC 29169
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~3.86 miles northwest of Cayce
  • Affordable hotel
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From$108 total
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Homewood Suites by Hilton Columbia - Columbia 230 Greystone Blvd., Columbia, SC 29210
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~3.91 miles north of Cayce
  • Affordable Downtown property
  • Hotel has 5 floors
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From$90 total
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Residence Inn by Marriott Columbia West / Lexington 122 Mathias Rd., West Columbia, SC 29169
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~4.07 miles northwest of Cayce
  • 3-star Highway property
  • Hotel has 108 rooms
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From$90 total
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Towneplace Suites Columbia West / Lexington in West Columbia 2915 Sunset Blvd., West Columbia, SC 29169
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~4.18 miles northwest of Cayce
  • Affordable property
  • Hotel has 111 suites
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From$90 total
Very Good 4.0 /5 Review Score Call BookMore Details
Comfort Inn Columbia in Columbia 911 Bush River Rd., Columbia, SC 29210
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~5.07 miles north of Cayce
  • Midscale Highway hotel
  • Gym is available on property
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From$74 total
Very Good 4.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Columbia 1144 Bush River Rd., Columbia, SC 29210
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~5.13 miles northwest of Cayce
  • Economy property
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From$72 total
Not Good 1.0 /5 Read Reviews Call BookMore Details

Next: See My Cayce Hotels with Pricing

Graph: Upcoming 20 Days of Cayce Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cayce, SC discounts available. The chart reflects the cheapest Cayce hotel for each day and each star rating category.

FAQs about hotels in Cayce

What are the most favored hotels in Cayce?

Country Inn & Suites Columbia Airport, Hampton Inn Columbia-Downtown Historic District and Econo Lodge Inn & Suites Cayce I-26 Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the upper-end hotels in Cayce?

Hilton Columbia Center, Sheraton Columbia Downtown Hotel and Marriott Columbia are the top 3 luxury hotels near Cayce city center.

What hotels are closest to the city center of Cayce?

Country Hearth Inn & Suites Cayce, Knights Inn Columbia Airport, and Econo Lodge Inn & Suites Cayce I-26 Airport are the properties closest to Cayce city center.

What are the best independent hotels in Cayce?

Hotel Trundle, Oyo Hotel Columbia Sc West and Carolina University Inn are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Cayce?

SpringHill Suites by Marriott Columbia Downtown, Courtyard by Marriott Columbia Downtown at USC and Marriott Columbia are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels in Cayce?

Econo Lodge Inn & Suites Cayce I-26 Airport, Sleep Inn Airport and Clarion Inn Columbia Airport are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Cayce?

Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih, Staybridge Suites Columbia An Ihg Hotel and Holiday Inn Columbia Downtown are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
The average traveler rating of the city of Cayce, SC shown above is 4.8 out of 5 based on 5 reviews
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