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Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels/Motels & Accommodations

Cambria Hotel Columbia Downtown The Vista
+1-888-389-4121

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1000 Lady Street, Columbia, SC 29201 ~3.19 miles northeast of Cayce
  • Mid-scale hotel
  • Pets Allowed
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Excellent 9.2 /10 Recent Reviews Call BookMore Details
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Marriott Columbia
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1200 Hampton St, Columbia, SC 292012826 ~3.46 miles northeast of Cayce
  • 3 star hotel
  • Check in time: 4:00 PM - 4:00 AM
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Excellent 9.5 /10 Hotel Reviews Call BookMore Details
Graduate by Hilton Columbia SC
+1-800-716-8490

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New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1619 Pendleton Street, Columbia, SC 29201 ~3.58 miles northeast of Cayce
  • High end hotel
  • Fitness / Gym is on-site
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Excellent 9.4 /10 Guest Reviews Call BookMore Details
Aloft by Marriott Columbia Downtown
+1-800-805-5223

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New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
823 Lady St, Columbia, SC 29201 ~3.09 miles northeast of Cayce
  • 3-star hotel
  • Pets are Allowed
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Excellent 9.0 /10 Review Score Call BookMore Details
Hilton Columbia Center
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
924 Senate St, Columbia, SC 29201 ~3.02 miles northeast of Cayce
  • Midscale property
  • 13 suites in hotel
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Very Good 8.9 /10 Review Score Call BookMore Details
Sheraton Columbia Downtown Hotel
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1400 Main St, Columbia, SC 292012806 ~3.41 miles northeast of Cayce
  • Three Star property
  • 17 floors in hotel
More Photos Photo of Sheraton Columbia Downtown Hotel
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Very Good 8.4 /10 Recent Reviews Call BookMore Details
Hotel Trundle
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1224 Taylor Street, Columbia, SC 29201 ~3.55 miles northeast of Cayce
  • 3 star property
  • Fitness center on property
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Excellent 9.8 /10 Reviews Call BookMore Details
Hilton Garden Inn Columbia Downtown SC
+1-888-311-4278

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1200 Pickens St., Columbia, SC 29201 ~3.70 miles northeast of Cayce
  • Affordable property
  • 123 rooms in hotel
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Average 7.6 /10 Read Reviews Call BookMore Details
Hyatt Place Columbia / Downtown/The Vista
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
819 Gervais Street, Columbia, SC 29201 ~3.01 miles northeast of Cayce
  • Affordable property
  • Pet-friendly
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Very Good 8.8 /10 Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown / The Vista
+1-888-734-9421

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New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
511 Lady Street, Columbia, SC 292013015 ~2.84 miles northeast of Cayce
  • 3 star property
  • Comp. Breakfast
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Very Good 8.8 /10 Hotel Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC
+1-888-841-5292

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New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
630 Assembly St, Columbia, SC 292014029 ~2.93 miles northeast of Cayce
  • Affordable hotel
  • Hotel has 9 floors
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Very Good 8.8 /10 Latest Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown
+1-888-455-5160

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New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1210 Pickens St, Columbia, SC 29201 ~3.67 miles northeast of Cayce
  • Affordable hotel
  • 5 suites in property
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Average 7.2 /10 Review Score Call BookMore Details
Hampton Inn Columbia-Downtown Historic District
+1-888-965-8297

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New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
822 Gervais St, Columbia, SC 292013126 ~2.99 miles northeast of Cayce
  • Mid-scale property
  • 123 rooms in hotel
More Photos Image of Hampton Inn Columbia-Downtown Historic District
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Very Good 8.8 /10 Recent Reviews Call BookMore Details
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Tru by Hilton Columbia Downtown
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
400 Gervais Street, Columbia, SC 29201 ~2.67 miles northeast of Cayce
  • Mid-scale hotel
  • Pets/Animals Allowed
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Excellent 9.4 /10 Read Reviews Call BookMore Details
Holiday Inn Columbia - Downtown by IHG
+1-888-749-6785

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New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1233 Washington Street, Columbia, SC 29201 ~3.46 miles northeast of Cayce
  • 3 star property
  • Check-in: 3:00 PM - anytime
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Very Good 8.8 /10 Recent Reviews Call BookMore Details
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Holiday Inn Express & Suites Columbia Downtown - The Vista by IHG
+1-888-878-9982

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New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
901 WASHINGTON STREET, Columbia, SC 29229 ~3.20 miles northeast of Cayce
  • Three Star property
  • Check in: 3:00 PM - anytime
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Very Good 8.7 /10 Latest Reviews Call BookMore Details
Hampton Inn & Suites Columbia / Southeast-Ft. Jackson
+1-888-389-4485

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New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
201 East Exchange Boulevard, Columbia, SC 29209 ~6.56 miles east of Cayce
  • Mid-scale property
  • Pets are Allowed
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Very Good 8.4 /10 Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
110 McSwain Drive, West Columbia, SC 291694804 ~3.77 miles northwest of Cayce
  • Midscale property
  • Pets Allowed
More Photos Photo of Hilton Garden Inn Columbia Airport
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Excellent 9.0 /10 Guest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Columbia Downtown
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
501 Taylor Street, Columbia, SC 29201 ~3.05 miles north of Cayce
  • Midscale property
  • 81 rooms in property
More Photos Exterior of Fairfield Inn & Suites by Marriott Columbia Downtown
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Very Good 8.6 /10 Read Reviews Call BookMore Details
Staybridge Suites Columbia by IHG
+1-800-716-8490

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New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1913 Huger Street, Columbia, SC 292012215 ~3.25 miles north of Cayce
  • Affordable property
  • Gym / Fitness Center Available
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Excellent 9.2 /10 Read Reviews Call BookMore Details
Hyatt Place Sumter / Downtown
+1-800-805-5223

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New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
18 North Main St, Sumter, SC 29150 ~41.75 miles east of Cayce
  • 3-star property
  • 93 rooms in property
More Photos Image of Hyatt Place Sumter / Downtown
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Excellent 9.2 /10 Read Reviews Call BookMore Details
Doubletree by Hilton Columbia SC
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
2100 Bush River Road, Columbia, SC 292237612 ~5.78 miles northwest of Cayce
  • 4-star hotel
  • 237 rooms in hotel
More Photos Image of Doubletree by Hilton Columbia SC
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Very Good 8.0 /10 Latest Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1125 Fort Congaree Trail, Cayce, SC 29033
  • 3 star property
  • Pets are OK
More Photos Photo of Courtyard by Marriott Columbia Cayce
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Excellent 9.0 /10 Hotel Reviews Call BookMore Details
Tru by Hilton Columbia Greystone
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
185 Stoneridge Drive, Columbia, SC 29210 ~3.66 miles north of Cayce
  • Three Star property
  • Hotel has 4 floors
More Photos Exterior of Tru by Hilton Columbia Greystone
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Very Good 8.9 /10 Read Reviews Call BookMore Details
Hilton Garden Inn Columbia / Harbison
+1-888-311-4278

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New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
434 Columbiana Dr, Columbia, SC 292121652 ~10.23 miles northwest of Cayce
  • Midscale hotel
  • 6 floors in hotel
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Very Good 8.8 /10 Latest Reviews Call BookMore Details
TownePlace Suites Columbia West / Lexington
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2915 SUNSET BLVD, West Columbia, SC 29169 ~4.19 miles northwest of Cayce
  • Midscale hotel
  • 111 rooms in hotel
More Photos Exterior of TownePlace Suites Columbia West / Lexington
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Excellent 9.2 /10 Recent Reviews Call BookMore Details
Homewood Suites by Hilton Columbia
+1-888-734-9421

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New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
230 Greystone Blvd, Columbia, SC 292108005 ~3.91 miles north of Cayce
  • Three Star property
  • Hotel has 81 suites
More Photos Exterior of Homewood Suites by Hilton Columbia
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Very Good 8.2 /10 Hotel Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Southeast Fort Jackson
+1-888-841-5292

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New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
7340 GARNERS FERRY ROAD, Columbia, SC 29209 ~6.86 miles east of Cayce
  • Three Star property
  • Fitness / Gym is on-site
More Photos Image of Home2 Suites by Hilton Columbia Southeast Fort Jackson
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Excellent 9.4 /10 Read Reviews Call BookMore Details
Aloft by Marriott Columbia Harbison
+1-888-455-5160

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New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
217 Lanneau Court, Columbia, SC 29212 ~9.44 miles northwest of Cayce
  • Mid-scale property
  • Hotel has an eco-friendly policy Read more
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Very Good 8.0 /10 Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia-Fort Jackson by IHG
+1-888-965-8297

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New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
7329 Garners Ferry Rd, Columbia, SC 292092110 ~6.70 miles east of Cayce
  • Affordable property
  • 5 floors in hotel
More Photos Exterior of Holiday Inn Express & Suites Columbia-Fort Jackson by IHG
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Very Good 8.3 /10 Read Reviews Call BookMore Details
Homewood Suites by Hilton Columbia Downtown
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
400 Gervais Street, Columbia, SC 29201 ~2.67 miles northeast of Cayce
  • Three Star hotel
  • 125 rooms in hotel
More Photos Image of Homewood Suites by Hilton Columbia Downtown
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Excellent 9.4 /10 Review Score Call BookMore Details
Hampton Inn & Suites Columbia Killian Road
+1-888-749-6785

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New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1310 Roberts Branch Pkwy, Columbia, SC 29203 ~13.54 miles northeast of Cayce
  • 3-star hotel
  • Free complimentary breakfast
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Excellent 9.2 /10 Reviews Call BookMore Details
Hilton Garden Inn Columbia Northeast
+1-888-878-9982

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New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
8910 Farrow Rd, Columbia, SC 29203 ~11.89 miles northeast of Cayce
  • 3-star property
  • Fitness + Health Center
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Excellent 9.0 /10 Review Score Call BookMore Details
Hyatt Place Columbia / Harbison
+1-888-389-4485

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New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1130 Kinley Road, Irmo, SC 290639633 ~10.47 miles northwest of Cayce
  • Mid-scale property
  • Hotel has 6 floors
More Photos Image of Hyatt Place Columbia / Harbison
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Very Good 8.0 /10 Recent Reviews Call BookMore Details
SpringHill Suites Sumter
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
2645 Broad St, Sumter, SC 29150 ~38.32 miles east of Cayce
  • 3 star property
  • Check-in time: 3:00 PM - anytime
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Excellent 9.4 /10 Reviews Call BookMore Details
Tru by Hilton Harbison Columbia
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
271 Columbiana Drive, Columbia, SC 29212 ~9.72 miles northwest of Cayce
  • Three Star hotel
  • 85 rooms in property
More Photos Image of Tru by Hilton Harbison Columbia
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Average 7.7 /10 Guest Reviews Call BookMore Details
Courtyard by Marriott Columbia Northeast / Fort Jackson Area
+1-800-716-8490

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New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
111 Gateway Corporate Blvd, Columbia, SC 292039612 ~11.65 miles northeast of Cayce
  • Midscale property
  • Gym is available on property
More Photos Exterior of Courtyard by Marriott Columbia Northeast / Fort Jackson Area
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Very Good 8.8 /10 Hotel Reviews Call BookMore Details
Country Inn & Suites by Radisson Columbia Airport, SC
+1-800-805-5223

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New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
2245 Airport Blvd, Cayce, SC 290331403
  • Three Star hotel
  • Shuttle from airport available
More Photos Photo of Country Inn & Suites by Radisson Columbia Airport, SC
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Very Good 8.6 /10 Recent Reviews Call BookMore Details
Hampton Inn Columbia-I-26 Airport
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1094 Chris Dr, West Columbia, SC 291694722 ~3.62 miles northwest of Cayce
  • Three Star hotel
  • Access to gym on-site
More Photos Photo of Hampton Inn Columbia-I-26 Airport
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Very Good 8.2 /10 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia-I-26 at Harbison Blvd by IHG
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
211 Lanneau Ct, Columbia, SC 292122261 ~9.42 miles northwest of Cayce
  • Affordable hotel
  • Check-in: 3:00 PM - midnight
More Photos Exterior of Holiday Inn Express & Suites Columbia-I-26 at Harbison Blvd by IHG
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Excellent 9.0 /10 Read Reviews Call BookMore Details
Residence Inn by Marriott Columbia Northeast / Fort Jackson Area
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2320 Legrand Rd, Columbia, SC 292235702 ~11.50 miles northeast of Cayce
  • 3-star hotel
  • Free complimentary breakfast
More Photos Photo of Residence Inn by Marriott Columbia Northeast / Fort Jackson Area
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Excellent 9.0 /10 Reviews Call BookMore Details
Comfort Suites Columbia at Harbison
+1-888-311-4278

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New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
750 Saturn Pkwy, Columbia, SC 292122265 ~9.16 miles northwest of Cayce
  • 3 star hotel
  • 82 suites in property
More Photos Photo of Comfort Suites Columbia at Harbison
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Very Good 8.0 /10 Review Score Call BookMore Details
Holiday Inn Express Hotel & Suites Blythewood by IHG
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
120 Creech Road, Blythewood, SC 29016 ~17.92 miles north of Cayce
  • Midscale hotel
  • Fitness + Health Center
More Photos Image of Holiday Inn Express Hotel & Suites Blythewood by IHG
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Very Good 8.6 /10 Latest Reviews Call BookMore Details
Fairfield by Marriott Inn & Suites Columbia Harbison
+1-888-734-9421

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New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
320 Columbiana Dr, Columbia, SC 292122252 ~9.82 miles northwest of Cayce
  • Affordable property
  • 84 rooms in hotel
More Photos Image of Fairfield by Marriott Inn & Suites Columbia Harbison
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Very Good 8.4 /10 Review Score Call BookMore Details
TownePlace Suites by Marriott Columbia Southeast / Ft. Jackson
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
250 East Exchange Blvd, Columbia, SC 292092172 ~6.57 miles east of Cayce
  • Affordable property
  • Hotel has 91 suites
More Photos Photo of TownePlace Suites by Marriott Columbia Southeast / Ft. Jackson
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Very Good 8.8 /10 Read Reviews Call BookMore Details
Hampton Inn & Suites Lexington Columbia
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
4751 Sunset Boulevard, Lexington, SC 29072 ~6.98 miles west of Cayce
  • Midscale hotel
  • Pets/Dogs Allowed
More Photos Exterior of Hampton Inn & Suites Lexington Columbia
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Excellent 9.6 /10 Hotel Reviews Call BookMore Details
Lexington Expo Hotel by IHG
+1-888-965-8297

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New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
108 Saluda Pointe Court, Lexington, SC 29072 ~5.90 miles northwest of Cayce
  • Affordable property
  • Hotel has 97 rooms
More Photos Image of Lexington Expo Hotel by IHG
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Excellent 9.0 /10 Review Score Call BookMore Details
Home2 Suites by Hilton Columbia Harbison
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
550 Columbiana Dr, Irmo, SC 29212 ~10.56 miles northwest of Cayce
  • 3-star property
  • Free breakfast
More Photos Photo of Home2 Suites by Hilton Columbia Harbison
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Very Good 8.0 /10 Hotel Reviews Call BookMore Details
Hampton Inn Columbia Northeast - Fort Jackson Area
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1551 Barbara Dr, Columbia, SC 29223 ~10.52 miles northeast of Cayce
  • Three Star property
  • 5 floors in hotel
More Photos Photo of Hampton Inn Columbia Northeast - Fort Jackson Area
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Very Good 8.4 /10 Hotel Reviews Call BookMore Details
Residence Inn by Marriott Columbia Northwest / Harbison
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
944 Lake Murray Blvd, Irmo, SC 29063 ~10.69 miles northwest of Cayce
  • Three Star hotel
  • 4 floors in hotel
More Photos Photo of Residence Inn by Marriott Columbia Northwest / Harbison
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Excellent 9.2 /10 Review Score Call BookMore Details

Next: See My Cayce Hotels with Pricing

FAQs about hotels in Cayce

What are the best rated hotels in Cayce?

Hotel Trundle, Marriott Columbia and Hampton Inn & Suites Lexington Columbia are the best rated hotels based on customer reviews in the last 365 days.

What are the 4-5 star hotels in Cayce?

Graduate by Hilton Columbia SC, Doubletree by Hilton Columbia SC and Cambria Hotel Columbia Downtown The Vista are the top 3 luxury hotels near Cayce city center.

What hotels are closest to the city center of Cayce?

Country Inn & Suites by Radisson Columbia Airport, SC, Courtyard by Marriott Columbia Cayce, and Homewood Suites by Hilton Columbia Downtown are the properties closest to Cayce city center.

What are the most popular independent hotels in Cayce?

The Garnet Goliath, Hotel Trundle and The Lantern Columbia are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels in Cayce?

Springhill Suites by Marriott Camden, Marriott Columbia and TownePlace Suites by Marriott Sumter are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels in Cayce?

Cambria Hotel Columbia Downtown The Vista, Quality Inn & Suites Columbia Harbison and Woodspring Suites Sumter Near Shaw Afb are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best Best Western hotels in Cayce?

Best Western Plus Lexington Inn and Best Western Executive Inn & Suites are the best rated Best Western branded hotels (based on user reviews score).

What are the most popular IHG hotels in Cayce?

Holiday Inn Express & Suites Lexington by IHG, Staybridge Suites Columbia by IHG and Holiday Inn Express & Suites Columbia-I-26 at Harbison Blvd by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
The average traveler rating of the city of Cayce, SC shown above is 4.8 out of 5 based on 5 reviews
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