Find hotels & motels in Murphysboro using the list below. Search for cheap and discounted hotel and motel rates in or near Murphysboro, IL for your upcoming personal or group trip. We provide the best Murphysboro Illinois hotel/motel rooms. Review the Murphysboro hotel list below to find the perfect lodging. We also have a map of the Murphysboro hotels. Need 5+ Rooms? Secure Murphysboro Group Hotel Rates
The Murphysboro center is approximately 6 miles west of Memorial Hospital Carbondale and 6 miles west of Carbondale Amtrak Station.