Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Overview
4250 Midamerica Lane, St. Louis, MO 63129 United States
near Exit 195 on I-55 (~0.1mi)
Near Barnes Jewish South Campus
Call to book 1-800-219-2797 by Res.ai
Group Sales: 1-800-906-2871
AI Insight

The hotel offers amenities such as parking, an elevator, a gym, a pool, a restaurant, WiFi/internet, laundry facilities, non-smoking rooms, breakfast, air conditioning, a 24/7 front desk, a kitchen, a business center, and meeting rooms.

Trusted

We are a part of Reservations Group, a trusted independent travel company since 2003. More Info

Highlights
Free WiFi
Free buffet breakfast
Wheelchair-accessible van parking
Wheelchair-accessible fitness center
Select your room
5.0
31-Jul-2026
"Great lobby and awesome breakfast area"

Great hotel! Super clean and modern attributes, like computer and work spaces. Friendly and helpful staff! Clean rooms! Love the built in luggage rack! Breakfast area was well stocked and clean! My compliments to the kitchen staff! Great job! Thank you! I would definitely stay here again!

(Individual traveler, booked 1 room)
Verified Review, stayed from Sat Jul 25 to Sun Jul 26 2026 at a $202.57 average nightly rate.
5.0
19-Jul-2026
"Excellent Stay"

Over night stay, room very clean and well appointed. Staff very helpful.

(Individual traveler, booked 1 room)
Verified Review, stayed from Sun Jul 19 to Mon Jul 20 2026 at a $135.99 average nightly rate.
5.0
16-May-2026
"Tailor at the front desk is great"

Clean room Great staff.

(Individual traveler, booked 1 room)
Verified Review, stayed from Thu May 14 to Sun May 17 2026 at a $183.00 average nightly rate.
5.0
01-Apr-2026
"Very clean room respectful friendly staff and better than than the usual hotel breakfast"

Excellant

(Individual traveler, booked 1 room)
Verified Review, stayed from Tue Mar 31 to Wed Apr 01 2026 at a $183.33 average nightly rate.
5.0
11-Jan-2026
"Great place"

We stayed for one night. Had warm cookies when we arrived. Rooms were clean and big. Breakfast was good.

(Group coordinator, booked 2 rooms)
Verified Review, stayed from Sat Jan 10 to Sun Jan 11 2026 at a $109.99 average nightly rate.
5.0
23-Nov-2025
"Very clean very hospitable people that worked there overall great experience"

I would recommend anybody who wants to go to a very nice clean good hotel with a great breakfast to Holiday Inn express.

(Individual traveler, booked 1 room)
Verified Review, stayed from Sat Nov 22 to Sun Nov 23 2025 at a $141.99 average nightly rate.
5.0
30-Sep-2025
"Great place to stay."

We arrived late and Hailey was at the front desk. She was so nice and helpful. Very personable. The bed was very comfortable and our room was very clean.

(Individual traveler, booked 1 room)
Verified Review, stayed from Sat Sep 27 to Sun Sep 28 2025 at a $181.46 average nightly rate.
View all reviews

Check-In 3:00 PM - 2:30 AM

Check-Out 11:00 AM

Year of Last Renovation: 2017

Floors: 4

Rooms: 99

Corridors: All Rooms Have Interior Hallways

Non Smoking Rooms: 99

Suites: 17

Room Windows: Windows Don't Open

Cleaning Frequency: Daily

Meeting Rooms: 2

Dist. to Food/Bars: 0.3 Mi

Dist. to 24hr Restaurant: 0.3 Mi

Dist. to Nearest Gym: On-site

Ownership: Midamerica Hotels Corp

Nightly Parking: $0

Total Taxes: 14.99%

Total Misc Fees: $0.00 USD

Cancellation: 6p day of arrival

Check-In Instructions:

  • Extra-person charges may apply and vary depending on property policy
  • Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
  • Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
  • This property accepts credit cards; cash is not accepted
  • Safety features at this property include a fire extinguisher
  • This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
  • 24-hour fitness facilities
  • 24-hour front desk
  • Banquet hall
  • Business center
  • Change of bed sheets (on request)
  • Change of towels (on request)
  • Check In: 3:00 PM - 2:30 AM
  • Check Out: 11:00 AM
  • Daily
  • Elevator
  • Free WiFi
  • Free breakfast
  • Free buffet breakfast
  • Free self parking
  • Housekeeping on request
  • LGBTQIA+ friendly
  • Meeting rooms
  • No single-use plastic straws
  • Number of indoor pools - 1
  • Pets not allowed
  • Pool sun loungers
  • Professional property host/manager
  • Safe-deposit box at front desk
  • Service animals are allowed
  • Service animals are exempt from fees/restrictions
  • Smoke-free property
  • Stair-free path to entrance
  • Vending machine
  • Visual alarms in hallways
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair accessible parking
  • Wheelchair accessible path of travel
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible fitness center
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible van parking

Yes, ask the front desk about our Greener Stay program

Express Start Breakfast is a full, hot buffet, included in all room rates. Make-your-own pancakes, serve up some eggs, meats, biscuits & gravy, oatmeal, cold cereal, yogurt, and much more!

Free, self-parking, on our surface lot, with plenty of room for buses, trucks, and trailers.

FREE WiFi, wired & wireless, throughout the building

Contactless check-out is available

Property follows a brand or regulatory agency's sanitization guidelines Clean Promise (IHG)

Essential workers only - NO

Free Express Start Breakfast

Have their own 100% Arabica Smart Roast Coffee

Free high-speed internet service in every room

eHost Online Concierge Service where guests can learn about hotel amenities, major airlines nearby, up-to-date local weather and even car rental services

Perfect for the business traveler on the go, Holiday Inn Express offers 24/7 hours & photocopy services

The Holiday Inn Express highlights above are subject to change without notice.

Day 1

Breakfast Rooster - Start your day with a tasty breakfast at Rooster, known for their crepes and located 3 miles from the hotel.
Lunch Pappy's Smokehouse - Indulge in mouthwatering smoked meats at Pappy's Smokehouse, just 4 miles away from the hotel.
Dinner Sugarfire Smoke House - Enjoy delicious BBQ dishes at Sugarfire Smoke House, located 2.5 miles from the hotel.
Activity Gateway Arch - Visit the iconic Gateway Arch, a symbol of St. Louis, located 15 miles from the hotel.

Day 2

Breakfast Southwest Diner - Enjoy a hearty breakfast at Southwest Diner, known for their Southwest-inspired dishes, located 3.5 miles from the hotel.
Lunch Bogart's Smokehouse - Delight in mouthwatering BBQ at Bogart's Smokehouse, just 4.5 miles away from the hotel.
Dinner The Shaved Duck - Savor delicious smoked meats and craft beers at The Shaved Duck, situated 5 miles from the hotel.
Activity Forest Park - Explore the beautiful Forest Park, home to various attractions including the St. Louis Zoo and Art Museum, located 10 miles from the hotel.

Day 3

Breakfast The Mud House - Start your day with a tasty breakfast at The Mud House, known for their coffee and breakfast dishes, located 4 miles from the hotel.
Lunch Bella's Frozen Yogurt - Enjoy a refreshing lunch at Bella's Frozen Yogurt, offering a variety of frozen yogurt flavors, just 3.5 miles away from the hotel.
Dinner Salt + Smoke - Indulge in delicious BBQ and comfort food at Salt + Smoke, situated 6 miles from the hotel.
Activity City Museum - Have a fun-filled day at the City Museum, an interactive museum with unique exhibits, located 12 miles from the hotel.

FAQs about Holiday Inn Express & Suites St. Louis South - I-55 by IHG

What time is check in?

Check in time is 3:00 PM - 2:30 AM based on the hotel's local time. Early check in may be available if requested at the front desk on the day of check-in.

What time is check out?

Check out time is 11:00 AM based on the hotel's local time. Late check out may be available if requested at the front desk during your stay.

How many rooms does Holiday Inn Express & Suites St. Louis South - I-55 by IHG have?

There are 99 rooms in the property.

Is there any meeting space at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Yes, they have 2 meeting rooms that can support various table layouts.

What kind of breakfast is at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Express Start Breakfast is a full, hot buffet, included in all room rates. Make-your-own pancakes, serve up some eggs, meats, biscuits & gravy, oatmeal, cold cereal, yogurt, and much more!

What parking is available at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Free, self-parking, on our surface lot, with plenty of room for buses, trucks, and trailers.

How much does internet cost?

FREE WiFi, wired & wireless, throughout the building

Is there a gym at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Yes, there is a gym/fitness area available on-site at the property.

Is there a pool at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Yes, there is a pool on-site at the property. 8a - 10p

Is there shuttle service at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Lambert International Airport, 22 miles, $40 taxi

Meeting Rooms and Banquet Rooms at Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Below are the meeting, banquet, conference and event spaces at Holiday Inn Express & Suites St. Louis South - I-55 by IHG.

Feel free to use the Holiday Inn Express & Suites St. Louis South - I-55 by IHG meeting space capacities chart below to help in your event planning. Hotel Planner specializes in St. Louis event planning for sleeping rooms and meeting space for corporate events, weddings, parties, conventions, negotiated rates and trade shows.

Jefferson Room
27 x 13 x 10 • 351 sqft.
Classroom
12
Classroom Meeting Layout
Boardroom
12
Boardroom Meeting Space
Room Details
Perfect space for a smaller meeting, interviews, reviews, presentation, etc. Small counter & wet sink, in room. 80" flat panel, wall-mounted TV, with presentation table. Electric at classroom tables, for laptop use.
Room Type:General Meeting Room
Floor Level:1
Natural Light?:No
Obstructions?No
Built In Screens?No
Built In Stage?No
Built In A/V?No
Mississippi Room
27 x 13 x 10 • 351 sqft.
Boardroom
18
Boardroom Meeting Space
Room Details
This room sets off of the breakfast area and has large sliding barn doors, which block out sound. There is a small counter and 80" flat panel, wall-mounted TV, for presentation. Great for a board meeting, small training, interviews, reviews, etc.
Room Type:Boardroom
Floor Level:1
Windows:1
Natural Light?:Yes
Obstructions?No
Built In Screens?No
Built In Stage?No
Built In A/V?No
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